Academic literature on the topic 'Hematopoietic stem cell niche'

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Journal articles on the topic "Hematopoietic stem cell niche"

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Wattrus, Samuel J., and Leonard I. Zon. "Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish." Blood Advances 2, no. 21 (2018): 3063–69. http://dx.doi.org/10.1182/bloodadvances.2018021725.

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Abstract Each stem cell resides in a highly specialized anatomic location known as the niche that protects and regulates stem cell function. The importance of the niche in hematopoiesis has long been appreciated in transplantation, but without methods to observe activity in vivo, the components and mechanisms of the hematopoietic niche have remained incompletely understood. Zebrafish have emerged over the past few decades as an answer to this. Use of zebrafish to study the hematopoietic niche has enabled discovery of novel cell–cell interactions, as well as chemical and genetic regulators of h
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Ribeiro-Filho, Antonio Carlos, Débora Levy, Jorge Luis Maria Ruiz, Marluce da Cunha Mantovani, and Sérgio Paulo Bydlowski. "Traditional and Advanced Cell Cultures in Hematopoietic Stem Cell Studies." Cells 8, no. 12 (2019): 1628. http://dx.doi.org/10.3390/cells8121628.

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Hematopoiesis is the main function of bone marrow. Human hematopoietic stem and progenitor cells reside in the bone marrow microenvironment, making it a hotspot for the development of hematopoietic diseases. Numerous alterations that correspond to disease progression have been identified in the bone marrow stem cell niche. Complex interactions between the bone marrow microenvironment and hematopoietic stem cells determine the balance between the proliferation, differentiation and homeostasis of the stem cell compartment. Changes in this tightly regulated network can provoke malignant transform
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Kandarakov, Oleg, Alexander Belyavsky, and Ekaterina Semenova. "Bone Marrow Niches of Hematopoietic Stem and Progenitor Cells." International Journal of Molecular Sciences 23, no. 8 (2022): 4462. http://dx.doi.org/10.3390/ijms23084462.

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The mammalian hematopoietic system is remarkably efficient in meeting an organism’s vital needs, yet is highly sensitive and exquisitely regulated. Much of the organismal control over hematopoiesis comes from the regulation of hematopoietic stem cells (HSCs) by specific microenvironments called niches in bone marrow (BM), where HSCs reside. The experimental studies of the last two decades using the most sophisticated and advanced techniques have provided important data on the identity of the niche cells controlling HSCs functions and some mechanisms underlying niche-HSC interactions. In this r
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Goldman, Devorah C., Alexis S. Bailey, Dana L. Pfaffle, Azzah Al Masri, Jan L. Christian, and William H. Fleming. "BMP4 regulates the hematopoietic stem cell niche." Blood 114, no. 20 (2009): 4393–401. http://dx.doi.org/10.1182/blood-2009-02-206433.

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Abstract Bone morphogenetic protein 4 (BMP4) is required for mesoderm commitment to the hematopoietic lineage during early embryogenesis. However, deletion of BMP4 is early embryonically lethal and its functional role in definitive hematopoiesis is unknown. Consequently, we used a BMP4 hypomorph to investigate the role of BMP4 in regulating hematopoietic stem cell (HSC) function and maintaining steady-state hematopoiesis in the adult. Reporter gene expression shows that Bmp4 is expressed in cells associated with the hematopoietic microenvironment including osteoblasts, endothelial cells, and m
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Fielding, Claire, and Simón Méndez-Ferrer. "Neuronal regulation of bone marrow stem cell niches." F1000Research 9 (June 16, 2020): 614. http://dx.doi.org/10.12688/f1000research.22554.1.

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The bone marrow (BM) is the primary site of postnatal hematopoiesis and hematopoietic stem cell (HSC) maintenance. The BM HSC niche is an essential microenvironment which evolves and responds to the physiological demands of HSCs. It is responsible for orchestrating the fate of HSCs and tightly regulates the processes that occur in the BM, including self-renewal, quiescence, engraftment, and lineage differentiation. However, the BM HSC niche is disturbed following hematological stress such as hematological malignancies, ionizing radiation, and chemotherapy, causing the cellular composition to a
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Esmaeli-Azad, Babak, Anand S. Srivastava, Cybele Frederico, Geraldo Martinez, Satoshi Yasukawa, and Ewa Carrier. "Artificial Hematopoietic Stem Cell Niche Sustains Growth and Differentiation of Human ES-Derived Early Hematopoietic Progenitors." Blood 110, no. 11 (2007): 1415. http://dx.doi.org/10.1182/blood.v110.11.1415.1415.

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Abstract Using a novel Microplate Biomaterial Microarray (MBM™) technology, we have created an artificial hematopoietic stem cell niche that can sustain growth and differentiation of human embryonic stem cells-derived (hES) early hematopoietic progenitors. This hydrogel based ex-vivo niche allows uploading of human embryonal stem cells, human mesenchymal stem cells (MSC), genes (bcl-2 preventing apoptosis and HoxB4 enhancing hematopoiesis) and extracellular matrices to support growth and differentiation of human ES cells. These experiments were done using NIH-approved hES cell lines H1 and H9.
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Chan, Charles, Ching-Cheng Chen, Daniel L. Kraft, et al. "Identification and Isolation of the Hematopoietic Stem Cell Niche Initiating Cell Population." Blood 112, no. 11 (2008): 3574. http://dx.doi.org/10.1182/blood.v112.11.3574.3574.

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Abstract Introduction: Identification and understanding of the cells and processes that can generate, sustain and influence the HSC niche and hematopoiesis are critical for the development of a more comprehensive knowledge of normal hematopoiesis, stem cell homing, trafficking, differentiation and hematopoietic pathology. Growth and renewal in many tissues are initiated by stem cells, supported by the microenvironment (niche) in which they reside. While recent work has begun to describe functional interactions between stem cells and their niches, little is known about the formation of stem cel
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Nishida, Chiemi, Kaori Sato-Kusubata, Yoshihiko Tashiro, et al. "MT1-MMP Plays a Critical Role in Hematopoiesis by Regulating HIF-Mediated Chemo-/Cytokine Gene Transcription within Niche Cells." Blood 120, no. 21 (2012): 2351. http://dx.doi.org/10.1182/blood.v120.21.2351.2351.

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Abstract Abstract 2351 Stem cells reside in a physical niche. The organization of cellular niches has been shown to play a key role in regulating normal stem cell differentiation, stem cell maintenance and regeneration. Various stem cell niches have been shown to be hypoxic, thereby maintaining the stem cell phenotype of e.g. hematopoietic stem cells (HSCs) or cancer stem cells. The bone marrow (BM) niche is a rich reservoir of tissue-specific pluripotent HSCs. Proteases such as matrix metalloproteinases (MMPs) have been implicated in cell movement, partly due to their proteolytic function, an
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Boulais, Philip E., and Paul S. Frenette. "Making sense of hematopoietic stem cell niches." Blood 125, no. 17 (2015): 2621–29. http://dx.doi.org/10.1182/blood-2014-09-570192.

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Abstract The hematopoietic stem cell (HSC) niche commonly refers to the pairing of hematopoietic and mesenchymal cell populations that regulate HSC self-renewal, differentiation, and proliferation. Anatomic localization of the niche is a dynamic unit from the developmental stage that allows proliferating HSCs to expand before they reach the bone marrow where they adopt a quiescent phenotype that protects their integrity and functions. Recent studies have sought to clarify the complexity behind the HSC niche by assessing the contributions of specific cell populations to HSC maintenance. In part
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Park, Dongsu. "The hematopoietic stem cell niche." Frontiers in Bioscience 17, no. 1 (2012): 30. http://dx.doi.org/10.2741/3913.

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Dissertations / Theses on the topic "Hematopoietic stem cell niche"

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Miladinović, Olivera. "Molecular profiling of the embryonic hematopoietic stem cell niche." Electronic Thesis or Diss., Sorbonne université, 2023. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2023SORUS025.pdf.

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Les cellules souches hématopoïétiques (CSH) constituent une population rare de cellules à la base du système hématopoïétique chez l’adulte. Au cours de l'ontogenèse, les premières CSH de type adulte sont générées de manière autonome dans la région Aorte-Gonades-Mésonephros (AGM) chez l’embryon de souris à la moitié de la gestation. Plus précisément, les CSH naissent à partir de cellules endothéliales aortiques au cours d’une transition cellule endothéliale-cellule hématopoïétique. Le microenvironnement hématopoïétique de l’AGM comprend divers types cellulaires incluant des cellules stromales m
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Franke, Katja. "Adhesion and Single Cell Tracking of Hematopoietic Stem Cells on Extracellular Matrices." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-77290.

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The local microenvironment of hematopoietic stem cells (HSCs) in the bone marrow -referred to as stem cell niche- is thought to regulate the balance of stem cell maintenance and differentiation by a complex interplay of extrinsic signals including spatial constraints, extracellular matrix (ECM) components and cell-cell interactions. To dissect the role of niche ECM components, a set of well-defined matrix biomolecular coatings including fibronectin, laminin, collagen IV, tropocollagen I, heparin, heparan sulphate, hyaluronic acid and co-fibrils of collagen I with heparin or hyaluronic acid wer
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Liu, Wei. "Rational targeting of Cdc42 in hematopoietic stem cell mobilization and engraftment." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1303845649.

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Kräter, Martin. "Bone marrow niche-mimetics modulate hematopoietic stem cell function via adhesion signaling in vitro." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-230268.

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As graft source for lymphoma or leukemia treatment, hematopoietic stem and progenitor cells (HSPCs) have been the focus of translational medicine for decades. HSPCs are defined by their self-renewing capacity and their ability to give rise to all mature blood cells. They are found anchored to a specialized microenvironment in the bone marrow (BM) called the hematopoietic niche. HSPCs can be enriched by sorting them based on the presence of the surface antigen CD34 before clinical or tissue engineering use. As these cells represent a minority in most graft sources and the amount of applicable c
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Kokkaliaris, Konstantinos [Verfasser], and Heinrich [Akademischer Betreuer] Leonhardt. "Identification of novel niche molecules controlling hematopoietic stem cell behavior / Konstantinos Kokkaliaris ; Betreuer: Heinrich Leonhardt." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1115144944/34.

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Shimoto, Manabu. "Numerous niches for hematopoietic stem cells remain empty during homeostasis." Kyoto University, 2017. http://hdl.handle.net/2433/226772.

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Sugimura, Ryohichi. "Non-canonical Wnt signaling maintains hematopoietic stem cell through Flamingo and Frizzled8 interaction in the niche." Thesis, Open University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580673.

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Wnt signaling is involved in self-renewal and maintenance ofhematopoietic stem cells (HSCs); however, the particular role of non-canonical Wnt signaling in regulating HSCs in vivo is largely unknown. Here I show Flamingo and Frizzled8, members of non-canonical Wnt signaling, both express in and functionally maintain quiescent long-term HSCs. Flamingo regulates Frizzled8 distribution at the interface between HSCs and N-cadherin + osteoblasts (N-cad+OBs that enrich osteoprogenitors) in the niche. I further show that N-cad+OBs predominantly express non-canonical Wnt ligands and inhibitors of cano
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Hazen, Amy L. "Inositol phospholipid and tyrosine phosphorylation signaling in the biology of hematopoietic stem cells." [Tampa, Fla] : University of South Florida, 2009. http://digital.lib.usf.edu/?e14.2829.

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Ordemann, Rainer, Duohui Jing, Ana-Violeta Fonseca, et al. "Hematopoietic stem cells in co-culture with mesenchymal stromal cells - modeling the niche compartments in vitro." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-177403.

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Background Hematopoietic stem cells located in the bone marrow interact with a specific microenvironment referred to as the stem cell niche. Data derived from ex vivo co-culture systems using mesenchymal stromal cells as a feeder cell layer suggest that cell-to-cell contact has a significant impact on the expansion, migratory potential and ‘stemness’ of hematopoietic stem cells. Here we investigated in detail the spatial relationship between hematopoietic stem cells and mesenchymal stromal cells during ex vivo expansion. Design and Methods In the co-culture system, we defined three distinct l
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Ordemann, Rainer, Duohui Jing, Ana-Violeta Fonseca, et al. "Hematopoietic stem cells in co-culture with mesenchymal stromal cells - modeling the niche compartments in vitro." Ferrata Storti Foundation, 2010. https://tud.qucosa.de/id/qucosa%3A28891.

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Background Hematopoietic stem cells located in the bone marrow interact with a specific microenvironment referred to as the stem cell niche. Data derived from ex vivo co-culture systems using mesenchymal stromal cells as a feeder cell layer suggest that cell-to-cell contact has a significant impact on the expansion, migratory potential and ‘stemness’ of hematopoietic stem cells. Here we investigated in detail the spatial relationship between hematopoietic stem cells and mesenchymal stromal cells during ex vivo expansion. Design and Methods In the co-culture system, we defined three distinct l
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Books on the topic "Hematopoietic stem cell niche"

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Turksen, Kursad, ed. Stem Cell Niche. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-508-8.

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Turksen, Kursad, ed. Stem Cell Niche. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9508-0.

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J, Forman Stephen, Blume Karl G, and Thomas E. Donnall, eds. Hematopoietic cell transplantation. 2nd ed. Blackwell Science, 1999.

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Klug, Christopher A., and Craig T. Jordan. Hematopoietic Stem Cell Protocols. Humana Press, 2001. http://dx.doi.org/10.1385/159259140x.

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Soiffer, Robert J., ed. Hematopoietic Stem Cell Transplantation. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-438-4.

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Bishop, Michael R., ed. Hematopoietic Stem Cell Transplantation. Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-78580-6.

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Bunting, Kevin D., ed. Hematopoietic Stem Cell Protocols. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-182-6.

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Bunting, Kevin D., and Cheng-Kui Qu, eds. Hematopoietic Stem Cell Protocols. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1133-2.

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Godin, Isabelle, and Ana Cumano. Hematopoietic Stem Cell Development. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-33535-3.

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Kondo, Motonari, ed. Hematopoietic Stem Cell Biology. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60327-347-3.

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Book chapters on the topic "Hematopoietic stem cell niche"

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Tan, Keai Sinn, Nathalie Brouard, and Daisuke Sugiyama. "Analysis of Hematopoietic Niche in the Mouse Embryo." In Stem Cell Niche. Springer New York, 2018. http://dx.doi.org/10.1007/7651_2018_176.

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Costa, Marta H. G., Tiago S. Monteiro, Susana Cardoso, Joaquim M. S. Cabral, Frederico Castelo Ferreira, and Cláudia L. da Silva. "Three-Dimensional Co-culture of Human Hematopoietic Stem/Progenitor Cells and Mesenchymal Stem/Stromal Cells in a Biomimetic Hematopoietic Niche Microenvironment." In Stem Cell Niche. Springer New York, 2018. http://dx.doi.org/10.1007/7651_2018_181.

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Iwasaki, Hiroko, and Toshio Suda. "Hematopoietic Stem Cells and Their Niche." In Hematopoietic Stem Cell Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-347-3_2.

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Chitteti, Brahmananda Reddy, Monique Bethel, Sherry L. Voytik-Harbin, Melissa A. Kacena, and Edward F. Srour. "In Vitro Construction of 2D and 3D Simulations of the Murine Hematopoietic Niche." In Stem Cell Niche. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-508-8_5.

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Sugiyama, Daisuke, and Tatsuya Sasaki. "Isolation of Embryonic Hematopoietic Niche Cells by Flow Cytometry and Laser Capture Microdissection." In Stem Cell Niche. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-508-8_6.

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Park, Sun H., Matthew R. Eber, Russell S. Taichman, and Yusuke Shiozawa. "Determining Competitive Potential of Bone Metastatic Cancer Cells in the Murine Hematopoietic Stem Cell Niche." In Stem Cell Niche. Springer New York, 2018. http://dx.doi.org/10.1007/7651_2018_178.

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Hoang, Van T., Isabel Hoffmann, Karina Borowski, et al. "Identification and Separation of Normal Hematopoietic Stem Cells and Leukemia Stem Cells from Patients with Acute Myeloid Leukemia." In Stem Cell Niche. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-508-8_19.

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Mise-Omata, Setsuko, Takahiro S. Doi, Kazuhiro Aoki, and Yuichi Obata. "Impact of Radiation on Hematopoietic Niche." In Stem Cell Biology and Regenerative Medicine. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21702-4_6.

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Childress, Paul J., Marta B. Alvarez, Brahmananda R. Chitteti, Melissa A. Kacena, and Edward F. Srour. "The Hematopoietic Stem Cell Niche: Cell-Cell Interactions and Quiescence." In Stem Cell Biology and Regenerative Medicine. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21702-4_1.

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Gottwald, Eric, Cordula Nies, Patrick Wuchter, Rainer Saffrich, Roman Truckenmüller, and Stefan Giselbrecht. "A Microcavity Array-Based 3D Model System of the Hematopoietic Stem Cell Niche." In Stem Cell Mobilization. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9574-5_7.

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Conference papers on the topic "Hematopoietic stem cell niche"

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Gee, A. P. "Hematopoietic Stem Cell Engineering: The Magic Bullet of the Next Millenium?" In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1317.

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Abstract Hematopoietic stem cell [HSC] therapy has its origins as hematological rescue following marrow ablative high-dose therapy for refractory cancers and myelodysplastic syndromes. In its simplest form, bone marrow is collected from a tissue-matched related normal donor and intravenously infused into the patient who has usually received high-dose chemo/radiotherapy for his or her disease. The stem cells migrate to the marrow spaces, where they multiply and differentiate to restore blood cell-forming activity and immune defenses in the recipient Restrictions in the availability of tissue-ma
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Giles, Amber J., Meera Murgai, Yorleny Vicioso, et al. "Abstract 3058: Bone marrow hematopoietic stem cell niche activation and mobilization fosters the metastatic niche." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3058.

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Giles, Amber J., Meera Murgai, Yorleny Vicioso, et al. "Abstract 4725: Hematopoietic stem cell niche activation and progenitor mobilization mediate cancer-associated immunosuppression and metastasis." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4725.

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Alonso, Salvador, Meng Su, Richard Jones, and Gabriel Ghiaur. "Abstract 4842: The stem cell niche detoxifies chemotherapy and protects malignant hematopoietic cells via expression of cytochrome P450 enzymes." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4842.

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Grubač, Siniša, Marko Cincović, Jože Starič, Marinković Došenović, Biljana Delić-Vujanović, and Jasna Prodanov-Radulović. "The relationship of the metabolism of iron, organic matter and phlebotomy with the erythropoiesis of ruminants." In Zbornik radova 26. medunarodni kongres Mediteranske federacije za zdravlje i produkciju preživara - FeMeSPRum. Poljoprivredni fakultet Novi Sad, 2024. http://dx.doi.org/10.5937/femesprumns24012g.

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Erythropesis is the process of making red blood cells and it is related to numerous factors in the body. Iron is important because of its role in the process of making hemoglobin. In addition to the mentioned iron, it is an indirect indicator of inflammation and is regulated at the systemic and cellular level, so its lack speaks of the overall health status of individuals. Fe deficiency in the body takes place through three phases. In the first phase, there is emptying of tissue depots, but its total amount in the circulation increases, then follows the second phase or the phase of real defici
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Park, ES, YJ Chung, and PD Aplan. "PO-020 Discrepancy in efficacy of disulfiram between NUP98-PHF23 fusion acute myelogenous leukaemia cell line andin vivomouse model: sharing normal hematopoietic stem cells niche." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.555.

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Luo, Biquan, Ben S. Lam, Sung Hyung Lee, et al. "Abstract LB-49: The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-49.

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"Dormancy regulation of hematopoietic stem cell." In Биоинформатика регуляции и структуры геномов / системная биология. ИЦиГ СО РАН, 2024. http://dx.doi.org/10.18699/bgrs2024-1.2-12.

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Ohsuga, Mieko, Yuma Tada, and Jun Ishikawa. "Interactive environment for hematopoietic stem-cell transplant patients." In 2017 International Conference on Virtual Rehabilitation (ICVR). IEEE, 2017. http://dx.doi.org/10.1109/icvr.2017.8007469.

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Bergeron, Anne, Cendrine Godet, Sylvie Chevret, et al. "Bronchial Disorders After Allogeneic Hematopoietic Stem Cell Transplantation." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4666.

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Reports on the topic "Hematopoietic stem cell niche"

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Dorshkind, Kenneth. Effects of Hematopoietic Stem Cell Age on CML Disease Progression. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada451341.

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Chapin, Kyle. The Role of Cyfip1 in Hematopoietic Stem Cell Specification in Zebrafish (Danio rerio). Iowa State University, 2024. https://doi.org/10.31274/cc-20250502-40.

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Chepko, Gloria, and Leena Hilakivi-Clarke. Role of the Stem Cell Niche in Hormone-induced Tumorigenesis in Fetal Mouse Mammary Epithelium. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada471087.

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Liu, Huan, Hui Huang, Jia Guo, et al. Effects of aerobic exercise on fatigue in patients with hematopoietic stem cell transplantation: a meta analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.5.0110.

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Wu, Xiaojin, Xiao Ma, Tiemei Song, Jie Liu, Yi Sun, and Depei Wu. Evidence Map for the Indirect Effects of CMV Infection on Patients with Allogeneic Hematopoietic Stem Cell transplantation. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0032.

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Wang, Xiaoyue, Hui Lu, Zhihao Liang, Liang Wang, and Ji Ma. Ixazomib combined with autologous stem cell transplantation for POEMS syndrome: a case report and meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.7.0061.

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Review question / Objective: POEMS syndrome is a rare monoclonal plasma cell proliferation disorder. At present, there is no unified treatment for POEMS syndrome. Here, we describe one case with POEMS syndrome. And we made a meta­analysis to assess the efficacy of treatment strategies in recent ten years. Search strategy: We searched relevant articles in PubMed, Embase and MEDLINE database for the period up to July 2021.The search strategy included the keywords: POEMS, Therapy, Drug Therapy, Biological Therapy, Combined Modality Therapy, Hematopoietic Stem Cell Transplantation, Immunotherapy,
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Ji, Conghua, Rongchen Dai, Hanting Wu, et al. Efficacy and safety of hematopoietic stem cell transplantation for hematologic malignancies: A protocol for an overview of systematic reviews and meta-analyses. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.5.0064.

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Yin, Xuewei, Liming Yu, Lingling Yin, et al. Efficacy and safety of tandem autologous hematopoietic stem cell transplantation in the treatment of multiple myeloma: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0007.

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Wang, Yan, Zhenzhen Wang, Jie Xu, et al. Efficacy and safety of haploidentical hematopoietic stem cell transplantation on severe aplastic anemia using busulfan-based myeloablative regimenA protocol for a Bayesian network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.1.0116.

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Yin, Xuewei, Liming Yu, Lingling Yin, et al. Efficacy and safety of tandem versus single autologous hematopoietic stem cell transplantation for the treatment of multiple myeloma: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.6.0112.

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