Relevant bibliographies by topics / Hemoglobin F

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Hemoglobin F'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Hemoglobin F"

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Olufemi, Akanni E., Oseni B. Sola, Bamisaye E. Oluwaseyi, Raji A. Ajani, Mewoyeka O. Olusoji, and Hassan R. Olubunmi. "Hemoglobin F level in different hemoglobin variants." Korean Journal of Hematology 46, no. 2 (2011): 118. http://dx.doi.org/10.5045/kjh.2011.46.2.118.

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Rees, D. C. "Hemoglobin F and Hemoglobin E/β-Thalassemia". Journal of Pediatric Hematology/Oncology 22, № 6 (2000): 567–72. http://dx.doi.org/10.1097/00043426-200011000-00025.

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Moscoso, H., C. R. Kiefer, A. Kutlar, and F. A. Garver. "Quantification of hemoglobins S, C, and F by a magnetic affinity immunoassay." Clinical Chemistry 34, no. 5 (1988): 902–5. http://dx.doi.org/10.1093/clinchem/34.5.902.

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Abstract This magnetic affinity immunoassay (MAIA) quantifies hemoglobins (Hb) S, C, and F in hemolysates from adults or newborns. Monospecific antisera to the hemoglobins are covalently conjugated to magnetic beads and reacted with the corresponding 125I-labeled hemoglobin. After centrifugation to separate the free and antibody-bound 125I-labeled hemoglobin, the amount of radioactive hemoglobin in the pellet is measured. To determine the concentration of the Hb under study, the percent inhibition of the reaction is quantified. The standard curve is established by adding known quantities of un
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Hirsch, R. E., M. J. Lin, and R. L. Nagel. "The inhibition of hemoglobin C crystallization by hemoglobin F." Journal of Biological Chemistry 263, no. 12 (1988): 5936–39. http://dx.doi.org/10.1016/s0021-9258(18)60656-8.

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Uygun, Vedat, and Gülsün Tezcan Karasu. "Hemoglobin F and Related Conditions." Van Medical Journal 23, no. 2 (2016): 229–34. http://dx.doi.org/10.5505/vtd.2016.96268.

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Reinhardt, D., D. Haase, C. Schoch, et al. "Hemoglobin F in myelodysplastic syndrome." Annals of Hematology 76, no. 3-4 (1998): 135–38. http://dx.doi.org/10.1007/s002770050377.

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Adachi, K., J. Pang, P. Konitzer, and S. Surrey. "Polymerization of recombinant hemoglobin F gamma E6V and hemoglobin F gamma E6V, gamma Q87T alone, and in mixtures with hemoglobin S." Blood 87, no. 4 (1996): 1617–24. http://dx.doi.org/10.1182/blood.v87.4.1617.bloodjournal8741617.

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To further understand determinants for Hemoglobin (Hb) S polymerization, as well as the inhibitory mechanism of Hb F on Hb S polymerization, Hb F variants containing Val-gamma 6 (Hb F gamma E6V) or Val-gamma 6, Thr-gamma 87 (Hb F gamma E6V, gamma Q87T) were expressed in yeast. The oxy form of Hb F gamma E6V was about 10-fold less stable to mechanical agitation than native oxy Hb F, which is similar to stability differences comparing oxy Hb S and oxy Hb A. Deoxy Hb F gamma E6V showed approximately 20-fold decreased solubility compared with native deoxy Hb F in high phosphate buffer and formed g
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Mosca, Andrea, Cristian Arsene, Renata Paleari, et al. "Standardization of hemoglobin A2 and hemoglobin F: Achievements and perspectives." Clinica Chimica Acta 567 (February 2025): 120087. https://doi.org/10.1016/j.cca.2024.120087.

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Gordeuk, Victor R., Andrew Campbell, Sohail Rana, et al. "Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease." Blood 114, no. 21 (2009): 4639–44. http://dx.doi.org/10.1182/blood-2009-04-218040.

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AbstractHydroxyurea and higher hemoglobin F improve the clinical course and survival in sickle cell disease, but their roles in protecting from pulmonary hypertension are not clear. We studied 399 children and adolescents with sickle cell disease at steady state; 38% were being treated with hydroxyurea. Patients on hydroxyurea had higher hemoglobin concentration and lower values for a hemolytic component derived from 4 markers of hemolysis (P ≤ .002) but no difference in tricuspid regurgitation velocity compared with those not receiving hydroxyurea; they also had higher hemoglobin F (P < .0
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Whitham, Megan, Jayson Pagaduan, Steven L. Clark, et al. "Validation of the Siggaard–Andersen Acid–Base Nomogram for Hemoglobin F: Implications for Fetal Cord Blood Gas Analysis." American Journal of Perinatology 36, no. 14 (2019): 1481–84. http://dx.doi.org/10.1055/s-0039-1677800.

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Objective The calculation of HCO3 and base excess in current blood gas analysis is based on the Siggaard–Andersen equation. One of the constants in this equation is dependent on the known buffering capacity of hemoglobin A. We sought to investigate differences in buffering capacity between adult hemoglobin A and fetal hemoglobin F as a potential explanation for the observed poor correlation between calculated base excess in umbilical cord blood and newborn outcomes. Such differences would influence a key constant in the Van Slyke/Siggaard–Andersen equation used to calculate HCO3 and base exces
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Dissertations / Theses on the topic "Hemoglobin F"

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Schneidereith, Tonya A. "The pharmacogenetics of fetal hemoglobin and f-cell variation." Available to US Hopkins community, 2003. http://wwwlib.umi.com/dissertations/dlnow/308076.

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Tsang, Tsui-ying Stella, and 曾璀瑩. "Role of chromosomal 6q23 intergenic region in the modulation of haemoglobin F production." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B50162652.

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The HBS1L-MYBintergenic region on chromosome 6q23 is a quantitative trait locus (QTL) of haemoglobin F (Hb F) expression. It shows characteristics of a distal regulatory regionwhich may affect expression of neighbouring genes including MYB. However, the exact functional role of this region on Hb F level is still unclear. Recently, a 3-bp deletion site in this intergenic region was found to be linked with high Hb F level and possess motifs for gene regulation, making it a candidate functional site of this QTL. Here we further investigate this region for its functional role in Hb F modulation.
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Hedblom, Sofia. "Detection and quantification of fetal hemoglobin in blood using flow cytometry." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176636.

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Analytical methods used clinically in Sweden for detection and quantification of fetal hemoglobin (HbF) in maternal blood are either the microscopic method Kleinhauer Betkes test (KBT) or high performance liquid chromatography. A more modern alternative to detect and quantify HbF+ erythrocytes is flow cytometry. The aim of this project was therefore to evaluate the commercial kit "Fetal Cell Count kit" using flow cytometry. The kit used two antibodies; one directed against the specific γ-chain of HbF protein and the other directed against the intracellular enzyme carbanhydrase (CA), which is f
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Carrocini, Gisele Cristine de Souza [UNESP]. "Influência da δβ-Talassemia ou de elementos de regulação em indivíduos com hemoglobina fetal aumentada na população da região Noroeste do Estado de São Paulo". Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/92516.

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Made available in DSpace on 2014-06-11T19:26:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-02-25Bitstream added on 2014-06-13T19:12:53Z : No. of bitstreams: 1 carrocini_gcs_me_sjrp.pdf: 1450758 bytes, checksum: 22d1c253bc1aae8bf01a4211133799fb (MD5)<br>A hemoglobina Fetal (Hb F), formada por duas cadeias globínicas alfa (α) e duas gama (γ) (α2 γ2), apresenta expressão reduzida em indivíduos adultos, variando de 0% a 1% do total de hemoglobinas. Os níveis aumentados de Hb F são decorrentes de mutações na família β- globina, que originam a Persistência Hereditária de Hemoglobina Fe
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Zhang, Jie. "Hemoglobin and dendrimer conjugates." 2005. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=232724&T=F.

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Alagic, Amer. "Conjugation of proteins to hemoglobin." 2004. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=80261&T=F.

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Wang, Cha-Jen, and 王家仁. "Evaluation of a Dual Program Hemoglobin A2/F/A1c Kit on the Bio-Rad D-10 Automated Hemoglobin Analysis." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/26393285894962580070.

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碩士<br>臺北醫學大學<br>醫學科學研究所<br>97<br>Detection and quantitation of hemoglobin (Hb) fractions is required for clinically relevant in two situations. First, the quantitation of HbA1c, the major glycated form of HbA, is an useful biomarker in the clinical management of diabetes. Second, the detection and quantitation of HbA1c, HbA2, HbF and various Hb variants is an essential method in the diagnosis of hemoglobinopathies (eg, thalassemia syndromes or sickle cell syndromes). On the analyzing HbA1c, we compared the performance of Dual program with current kit (HbA1c program) on Bio-Rad D-10 HPLC analyz
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Hu, Dongxin. "A new cross-linked dendrido hemoglobin." 2005. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=788955&T=F.

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Ship, Noam. "Multidisciplinary studies of the properties of chemically modified hemoglobin." 2005. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=232720&T=F.

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Hu, Dongxin. "The effects of inter-tetrameric link structure on cooperativity in novel hemoglobin bis-tetramers." 2009. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=968430&T=F.

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Book chapters on the topic "Hemoglobin F"

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Winterbourn, Christine C. "[26] Oxidative reactions of hemoglobin." In Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants. Elsevier, 1990. http://dx.doi.org/10.1016/0076-6879(90)86118-f.

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Quirolo, Keith. "Sickle Cell Anemia." In Clinical Studies in Medical Biochemistry. Oxford University PressNew York, NY, 2006. http://dx.doi.org/10.1093/oso/9780195176872.003.0002.

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Abstract The patient was an 11-year-old girl diagnosed at birth by newborn screening as having hemoglobin F and hemoglobin S.She was subsequently determined to be hemoglobin SS. She had a long history of complications of her sickle cell disease, beginning with splenic sequestration at 6 months of age.At that time, she was treated with transfusions and eventually required a partial splenectomy. She was admitted to the hospital at 19 months of age with acute chest syndrome as a complication of respiratory syncytial viral infection.
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Nigam, Nitu, Prithvi Kumar Singh, Suhasini Bhatnagar, Sanjay Kumar Nigam, and Anil Kumar Tripathi. "An Early Diagnosis of Thalassemia: A Boon to a Healthy Society." In Blood - Updates on Hemodynamics and Thalassemia. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.100357.

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The β-thalassemia is a hereditary blood disorders, characterized by reduced or absent synthesis of the hemoglobin beta chain that cause microcytic hypochromic anemia. An early diagnosis, economical test, awareness programs and prenatal screening will be a milestone for the eradication of this genetic disorder and to reduce burden of the health sector of a country subsequently the economics. Initially, the diagnosis of β-thalassemia depends on the hematological tests with red cell indices that disclosed the microcytic hypochromic anemia. Hemoglobin analysis shows the abnormal peripheral blood s
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Perutz, Max F. "The Second Secret of Life." In I Wish I’d Made You Angry Earlier. Oxford University PressOxford, 1994. http://dx.doi.org/10.1093/oso/9780198505310.003.0024.

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Abstract In 1937,1 chose hemoglobin as the protein whose structure I wanted to solve, but it proved so much more complex than any solved before that it eluded me for more than 20 years. First success came in 1959, when Ann F. Cullis, Hilary Muirhead, Michael G. Rossmann, Tony C.T. North, and I first unraveled the architecture of the hemoglobin molecule in outline. We felt like explorers who have discovered a new continent, but it was not the end of the voyage, because our much-admired model did not reveal its inner workings —it provided no hint about the molecular mechanism of respiratory tran
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Quirolo, Keith. "Sickle Cell Anemia." In Clinical Studies In Medical Biochemistry. Oxford University PressNew York, NY, 2006. http://dx.doi.org/10.1093/oso/9780195147322.003.0002.

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Abstract The patient was an 11-year-old girl diagnosed at birth by newborn screening as having hemoglobin F and hemoglobin S. She was subsequently determined to be hemoglobin SS. She had a long history of complications of her sickle cell disease, beginning with splenic sequestration at 6 months of age. At that time, she was treated with transfusions and eventually required a partial splenectomy. She was admitted to the hospital at 19 months of age with acute chest syndrome as a complication of respiratory syncytial viral infection. Over the next several years, she had recurrent episodes of rea
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Patel, Simran, Armaan Shah, Ryan Kaiser, and Raj Wadgaonkar. "Effects of Beta-Thalassemia on COVID-19 Outcomes." In Thalassemia Syndromes - New Insights and Transfusion Modalities. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.110000.

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Beta-thalassemia is a hemoglobinopathy caused by mutations in the beta-globin chain. This disrupts hemoglobin production and can potentially result in severe anemia. There has been a rise in COVID-19 cases over the last 2 years, with a predominant effect on the respiratory and vascular systems of the body. Since beta-thalassemia is the most common inherited single-gene disorder in the world, investigating the impact of COVID-19 on these patients is important. Some theories suggest that patients with beta-thalassemia will be more susceptible to COVID-19 and have worse outcomes due to their unde
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Herman, Elizabeth, and Marie McDonnell. "Case 12: The Worst Case Scenario: Severe HHS in a Relatively Young Man." In Diabetes Case Studies: Real Problems, Practical Solutions. American Diabetes Association, 2015. http://dx.doi.org/10.2337/9781580405713.12.

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A 48-year-old man was brought to the emergency department (ED) after being found in his bed unresponsive. The patient’s medical history was notable for remote alcohol abuse, hypertension, and hyperlipidemia. He weighed 103 kg. In the ED, the patient was febrile at 101.1°F, BP 151/79 mmHg, HR 80 bpm, and O2 saturation 99%. Because of the altered mental status, he was intubated for airway protection. On arrival, the fingerstick glucose read “HI” (≥600 mg/dL). The patient had no history of diabetes and a hemoglobin A1c (HbA1c) was 5.1% 1 year prior.
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Conference papers on the topic "Hemoglobin F"

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"Hemoglobin-binding 2'-F-modified RNA aptamers: structure studies and analytical application." In Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) :. Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences, 2022. http://dx.doi.org/10.18699/sbb-2022-447.

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Worden, Katherine L., Yulin Song, Xin Jiang, Anca Constantinescu, Ralph P. Mason, and Hanli Liu. "Tumor oximetry: a comparison between near-infrared frequency-domain spectroscopy of hemoglobin saturation and 19F MRI of hexafluorobenzene." In BiOS '99 International Biomedical Optics Symposium, edited by Britton Chance, Robert R. Alfano, and Bruce J. Tromberg. SPIE, 1999. http://dx.doi.org/10.1117/12.356786.

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Silva, Lorena Késsia de Figueiredo, Mariane dos Santos Duarte Spinelli, Edis Belini Junior, et al. "Importância da associação de métodos cromatográficos e moleculares na confirmação da Hemoglobina Deer Lodge." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.10142.

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Objetivo: Demonstrar a importância da associação de metodologias laboratoriais para confirmação diagnóstica de hemoglobina (Hb) rara. Método: Relato de caso de criança de 2 anos, sexo masculino, encaminhado para realização de cirurgia por motivo de extirpação e supressão de lesão de pele, por interferência do frênulo lingual. Chegou à unidade de referência com resultado de triagem neonatal compatível com doença falciforme (S/b+ talassemia com Hb fetal elevada), sem histórico familiar da doença e nascido por parto normal sem icterícia. Posteriormente, foi solicitada investigação de hemoglobinop
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Gragnato, T., SBMC Rodrigues, EY Marcelino, and E. Souza. "A IMPORTÂNCIA DA DEFINIÇÃO E DA COMUNICAÇÃO DE VALORES CRÍTICOS NO LABORATÓRIO CLÍNICO." In Resumos do 55º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s2.8223.

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Objetivo: A maioria dos exames realizados em laboratórios considerados “ambulatoriais” não possuem implicações diagnósticas e terapêuticas que necessitem de ações imediatas, entretanto, alguns exames podem apresentar resultados que indiquem situações de risco a quem está realizado. Cerca de 70% das decisões médicas são tomadas tendo, como base, os exames laboratoriais. O objetivo deste trabalho é demonstrar a importância da definição e da comunicação dos resultados críticos para os pacientes atendidos e como esse apoio diagnóstico e terapêutico impacta positivamente nas decisões por parte dos
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Ou, Junjie, Shuwen Wang, Carolyn L. Ren, and Janusz Pawliszyn. "Preparation of Poly(Dimethylsiloxane) Chip-Based Cartridge for Isoelectric Focusing and Whole-Channel Imaging Detection." In 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2008. http://dx.doi.org/10.1115/micronano2008-70303.

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A poly(dimethylsiloxane) (PDMS) microfluidic chip-based cartridge was fabricated by sandwiching commercial dialysis membrane and inserting fused-silica capillary into the end of channel according to the principle and structure of a commercial fused-silicon capillary-based cartridge, which can adapt to an IEF analyzer for isoelectric focusing with whole channel imaging detection (IEF-WCID). The novel design of sandwiching membrane in this chip not only eliminated the unfavorable hydrodynamic pressure, leading to poor IEF reproducibility, but made the sample injection much easy. Thus the reprodu
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Vihar, Jangala Sai, and Deepak Mulajker. "A Descriptive Study to Assess the Association of Geriatric Score with Observed Chemo Toxicity in Cancer Patients Older than 60 Years." In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735373.

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Abstract Introduction Cancer is the leading cause of death worldwide with elderly patients being predominantly affected. There seems to be a bias against administering chemotherapy to elderly patients with fewer elderly patients receiving chemotherapy as compared with their stagematched younger patients because of concerns about their capacity to endure treatment. To make personalized treatment decisions and to anticipate serious adverse effects, a toxicity prediction tool that can be computed at the bedside is the need of the hour. This well-validated score has not been tested in the Indian p
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Gonçalves, LF, FRO Silva, BC Dal Pont, ACS Padilha, P. Haas, and SL Blatt. "RUNNING HEAD: AVALIAÇÃO DA ANEMIA NAS DISFUNÇÕES TIROIDEANAS." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.6856.

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Objetivo: O objetivo deste estudo foi avaliar as alterações hematológicas e a frequência da anemia em pacientes diagnosticados com disfunções tireoidianas. Método: Foram analisados 145 prontuários de pacientes com relato de diagnóstico disfunção tireoidiana; 102 eram do sexo feminino e 43 do masculino, atendidos no período de 1º de janeiro de 2011 a 28 de fevereiro de 2018. Todos foram selecionados de acordo com as diversas CIDs de disfunção tireoidiana. Conclusão: Entre as comorbidades encontradas, destaca-se a relação estatística de diabetes, hipertensão arterial sistêmica e doenças cardiova
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Reports on the topic "Hemoglobin F"

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พงษ์สามารถ, สุนันท์, สุกัญญา เจษฎานนท์ та นรานินทร์ มารคแมน. การศึกษาความปลอดภัยและความเป็นพิษของการบริโภค สารสกัดคล้ายเพคตินจากเปลือกทุเรียน : รายงานวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 1989. https://doi.org/10.58837/chula.res.1989.9.

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การศึกษาความปลอดภัยของการบริโภคสารคล้ายเพคตินสกัดจากเปลือกทุเรียนในสัตว์ทดลองหนู (mice) โดยการป้อนให้สัตว์ทดลองกินสารสกัดเปลือกทุเรียนในรูปของสารสกัด crude fraction (F I) และสารสกัด partially purify fraction (F II) และให้กินอาหารและน้ำตลอดเวลาตามปกติ ผลการทดสอบความปลอดภัยเบื้องต้นโดยป้อนสารสกัดให้กลุ่มสัตว์ทดลองกินทุกวันในขนาดสูงมากติดต่อกันเป็นเวลานาน 10 วัน พบว่าอัตราการเพิ่มน้ำหนักของสัตว์ทดลองในกลุ่มที่ป้อน F I ขนาด 0.125 g/kg/d กลุ่มที่ป้อน F III ขนาด 0.125 g/kg/d 0.25 g/kg/d และ 0.5 g/kg/d กับกลุ่มที่ป้อน pectin ขนาด 0.125 g/kg/d และ 0.5 g/kg/d ตลอดเวลา 10 วัน มีการเพิ่มของน้ำหนักตัวได้ด
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