Academic literature on the topic 'Hemoglobin percentage'
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Journal articles on the topic "Hemoglobin percentage"
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Rutherford-Parker, Nicola J., Sean T. Campbell, Jennifer M. Colby, and Zahra Shajani-Yi. "Voxelotor Treatment Interferes With Quantitative and Qualitative Hemoglobin Variant Analysis in Multiple Sickle Cell Disease Genotypes." American Journal of Clinical Pathology 154, no. 5 (2020): 627–34. http://dx.doi.org/10.1093/ajcp/aqaa067.
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Abstract Objectives Voxelotor was recently approved for use in the United States as a treatment for sickle cell disease (SCD) and has been shown to interfere with the quantitation of hemoglobin (Hb) S percentage. This study aimed to determine the effect of voxelotor on the quantitation of hemoglobin variant levels in patients with multiple SCD genotypes. Methods In vitro experiments were performed to assess the impact of voxelotor treatment on hemoglobin variant testing. Whole blood samples were incubated with voxelotor and then analyzed by routinely used quantitative and qualitative clinical laboratory methods (high-performance liquid chromatography [HPLC], capillary zone electrophoresis [CZE], and acid and alkaline electrophoresis). Results Voxelotor modified the α-globin chain of multiple hemoglobins, including HbA, HbS, HbC, HbD-Punjab, HbE, HbA2, and HbF. These voxelotor-hemoglobin complexes prevented accurate quantitation of multiple hemoglobin species, including HbS, by HPLC and CZE. Conclusions Technical limitations in quantifying HbS percentage may preclude the use of HPLC or CZE for monitoring patients treated with voxelotor. Furthermore, it is unclear whether HbS-voxelotor complexes are clinically equivalent to HbS. Consensus guidelines for reporting hemoglobin variant percentages for patients taking voxelotor are needed, as these values are necessary for determining the number of RBC units to exchange in acute situations.
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Bimantara, Gama, Angga Hardiansyah, and Darmu’in. "Hubungan Status Gizi, Persen Lemak Tubuh, dan Kadar Hemoglobin Terhadap Kualitas VO2 Maks Siswa Sekolah Sepak Bola Sport Supaya Sehat Semarang." Jurnal Gizi 12, no. 1 (2023): 20. http://dx.doi.org/10.26714/jg.12.1.2023.20-26.
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Background: Have a good nutritional status, ideal body fat percentage and normal hemoglobin levels are needed for maintain physical endurance, physical fitness and help to improve the performance of football athletes. When the nutritional status and body fat levels are not ideal, it will interfere athlete mobility. Low hemoglobin levels could disrupt the metabolism of energy that can make an athlete have downgrade quality. Purpose: Know the relationship of nutritional status, body fat percentage, and hemoglobinlevels on the quality of VO2 max student levels from Sport Supaya Sehat (SSS) football school Semarang. Methods: This research was conducted with a cross sectional design at Sport Supaya Sehat (SSS) football school Semarang. All population is a sample which is has 56 respondent. Themeasured data are nutritional status was assessed with body mass index by age, body fat percentage was assessed using Bioelectrical Impedance Analysis, hemoglobin levels was measured using Easytouch GCHb tools and cardiorespiratory endurance was assessed using Yo-Yo test method. Bivariate analysis used Gamma test. Result: The majority characteristics of respondents are have a good nutritional status(69,6%), moderate fat percentages(62,5%), normal hemoglobin levels(71,4%), and good quality of VO2 max levels(55,4%). Bivariate analitical result are nutritional status and body fat percentage has no significant relationship with VO2 max quality levels (p>0,05). Hemoglobin level has significant relationship with VO2 max quality levels (p<0,05). Conclusion: There is a significant relationship between hemoglobin levels with VO2 max quality levels.Key words: Nutritional status; body fat percentage; hemoglobin; VO2 max
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Moscoso, H., C. R. Kiefer, A. Kutlar, and F. A. Garver. "Quantification of hemoglobins S, C, and F by a magnetic affinity immunoassay." Clinical Chemistry 34, no. 5 (1988): 902–5. http://dx.doi.org/10.1093/clinchem/34.5.902.
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Abstract This magnetic affinity immunoassay (MAIA) quantifies hemoglobins (Hb) S, C, and F in hemolysates from adults or newborns. Monospecific antisera to the hemoglobins are covalently conjugated to magnetic beads and reacted with the corresponding 125I-labeled hemoglobin. After centrifugation to separate the free and antibody-bound 125I-labeled hemoglobin, the amount of radioactive hemoglobin in the pellet is measured. To determine the concentration of the Hb under study, the percent inhibition of the reaction is quantified. The standard curve is established by adding known quantities of unlabeled hemoglobin before adding 125I-labeled hemoglobin. The amount of Hb S, Hb C, or Hb F present in hemolysates is determined by measuring the percentage of inhibition and extrapolating the concentration from the standard curve. Results agree well with values for Hb S and Hb C obtained by "high-performance" liquid chromatography and RIA and for Hb F as measured by alkali denaturation and RIA. This assay can be completed in 1 h and is more sensitive than enzyme immunoassay or RIA: we can detect proportions of Hb S and Hb C as low as 1% of total Hb, and Hb F as low as 0.05%.
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LOTTRUP, M. C., and H. LEBEL. "On Determination of the Hemoglobin Percentage from the Sedimentation Rate1." Acta Medica Scandinavica 82, no. 1-2 (2009): 170–72. http://dx.doi.org/10.1111/j.0954-6820.1934.tb09397.x.
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Scabet, Michael, Cheryl J. Mcroyan, J. Grace Liu, Richard C. Morris, and Paul I. Liu. "A Rapid Assessment of Percentage Hemoglobin-S in Whole Blood." American Journal of Clinical Pathology 86, no. 6 (1986): 759–61. http://dx.doi.org/10.1093/ajcp/86.6.759.
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Purvis, Taylor E., C. Rory Goodwin, Camilo A. Molina, Steven M. Frank, and Daniel M. Sciubba. "Percentage change in hemoglobin level and morbidity in spine surgery patients." Journal of Neurosurgery: Spine 28, no. 3 (2018): 345–51. http://dx.doi.org/10.3171/2017.7.spine17301.
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OBJECTIVEThe aim of this study was to characterize the association between percentage change in hemoglobin (ΔHb)—i.e., the difference between preoperative Hb and in-hospital nadir Hb concentration—and perioperative adverse events among spine surgery patients.METHODSPatients who underwent spine surgery at the authors’ institution between December 4, 2008, and June 26, 2015, were eligible for this retrospective study. Patients who underwent the following procedures were included: atlantoaxial fusion, subaxial anterior cervical fusion, subaxial posterior cervical fusion, anterior lumbar fusion, posterior lumbar fusion, lateral lumbar fusion, excision of intervertebral disc, and excision of spinal cord lesion. Data on intraoperative transfusion were obtained from an automated, prospectively collected, anesthesia data management system. Data on postoperative hospital transfusions were obtained through an Internet-based intelligence portal. Percentage ΔHb was defined as: ([preoperative Hb − nadir Hb]/preoperative Hb) × 100. Clinical outcomes included in-hospital morbidity and length of stay associated with percentage ΔHb.RESULTSA total of 3949 patients who underwent spine surgery were identified. Of these, 1204 patients (30.5%) received at least 1 unit of packed red blood cells. The median nadir Hb level was 10.6 g/dl (interquartile range 8.7–12.4 g/dl), yielding a mean percentage ΔHb of 23.6% (SD 15.4%). Perioperative complications occurred in 234 patients (5.9%) and were more common in patients with a larger percentage ΔHb (p = 0.017). Hospital-related infection, which occurred in 60 patients (1.5%), was also more common in patients with greater percentage ΔHb (p = 0.001).CONCLUSIONSPercentage ΔHb is independently associated with a higher risk of developing any perioperative complication and hospital-related infection. The authors’ results suggest that percentage ΔHb may be a useful measure for identifying patients at risk for adverse perioperative events.
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Nakazawa, M., MT Mitjavila, N. Debili, et al. "KU 812: a pluripotent human cell line with spontaneous erythroid terminal maturation." Blood 73, no. 7 (1989): 2003–13. http://dx.doi.org/10.1182/blood.v73.7.2003.2003.
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Abstract A human leukemic cell line KU 812 was recently established and described as a basophilic cell line. In the present study we show that KU 812 and two of its clones are at least bipotent: in addition to a minor component of basophils, the majority of KU 812 cells belongs to the erythroid cell lineage with a significant percentage (about 15%) of mature hemoglobinized erythroblasts. This terminal differentiation is associated with the synchronized synthesis of the main erythroid proteins, including glycophorins, spectrin beta chain, band 3, and hemoglobin. The predominant hemoglobins are adult, fetal, and Bart's hemoglobin. Adult hemoglobin represented up to 75% of all hemoglobins in the KU 812 F clone in passages containing a high number of mature erythroblasts. Transcripts of all human globin chains were present with ten times less embryonic chain messenger RNA (mRNA) than alpha-, beta- or gamma-chain mRNA. Hemin slightly increased the total hemoglobin production of the cell line, especially gamma-globin chain synthesis, but did not modify the percentage of hemoglobinized cells. Phorbol myristate acetate (PMA) had a complex effect, inducing a proportion of KU 812 cells to adhere to the plastic culture flask. The adherent cell fraction expressed a very low level of specific erythroid proteins, but their ultrastructure was consistent with immature erythroid cells. In contrast, approximately 40% of the nonadherent cells were mature erythroid cells. Cell-sorting experiments showed that this paradoxic effect of PMA is mostly due to cell selection, the more mature cells being unable to adhere. In addition, KU 812 F was found to be sensitive to erythropoietin, which slightly increased its plating efficiency range (from 0% to 50%) in semisolid medium and enhanced hemoglobin accumulation twofold. In binding experiments using 125I erythropoietin, a single class of high-affinity Epo receptors (Kd: 250 pM) was detected by binding with a density of 205 receptors per cell. The KU 812 cell line is therefore a unique model for studying cell commitment toward different hematopoietic lineages and erythroid differentiation.
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Nakazawa, M., MT Mitjavila, N. Debili, et al. "KU 812: a pluripotent human cell line with spontaneous erythroid terminal maturation." Blood 73, no. 7 (1989): 2003–13. http://dx.doi.org/10.1182/blood.v73.7.2003.bloodjournal7372003.
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A human leukemic cell line KU 812 was recently established and described as a basophilic cell line. In the present study we show that KU 812 and two of its clones are at least bipotent: in addition to a minor component of basophils, the majority of KU 812 cells belongs to the erythroid cell lineage with a significant percentage (about 15%) of mature hemoglobinized erythroblasts. This terminal differentiation is associated with the synchronized synthesis of the main erythroid proteins, including glycophorins, spectrin beta chain, band 3, and hemoglobin. The predominant hemoglobins are adult, fetal, and Bart's hemoglobin. Adult hemoglobin represented up to 75% of all hemoglobins in the KU 812 F clone in passages containing a high number of mature erythroblasts. Transcripts of all human globin chains were present with ten times less embryonic chain messenger RNA (mRNA) than alpha-, beta- or gamma-chain mRNA. Hemin slightly increased the total hemoglobin production of the cell line, especially gamma-globin chain synthesis, but did not modify the percentage of hemoglobinized cells. Phorbol myristate acetate (PMA) had a complex effect, inducing a proportion of KU 812 cells to adhere to the plastic culture flask. The adherent cell fraction expressed a very low level of specific erythroid proteins, but their ultrastructure was consistent with immature erythroid cells. In contrast, approximately 40% of the nonadherent cells were mature erythroid cells. Cell-sorting experiments showed that this paradoxic effect of PMA is mostly due to cell selection, the more mature cells being unable to adhere. In addition, KU 812 F was found to be sensitive to erythropoietin, which slightly increased its plating efficiency range (from 0% to 50%) in semisolid medium and enhanced hemoglobin accumulation twofold. In binding experiments using 125I erythropoietin, a single class of high-affinity Epo receptors (Kd: 250 pM) was detected by binding with a density of 205 receptors per cell. The KU 812 cell line is therefore a unique model for studying cell commitment toward different hematopoietic lineages and erythroid differentiation.
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., Sambedna, Amit Kumar, and Rita Chakore. "Study of relationship between umbilical cord blood hemoglobin percentage and perinatal asphyxia." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 10 (2020): 4114. http://dx.doi.org/10.18203/2320-1770.ijrcog20204297.
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Background: Perinatal asphyxia may be caused by perinatal anemia. The pathophysiology and neurodevelopment effects are theoretically different from other causes of fetal asphyxia. Severe asphyxia can occur in infants around the time of birth by various reasons. The aim of this study to find the relationship between cord blood hemoglobin and perinatal asphyxia.Methods: This was a retrospective comparative study in department of OBG In tertiary care health centre. Umbilical cord blood samples were collected from 100 newborns with asphyxia at birth as study group and 100 newborns with non asphyxia as control group. Hemoglobin was measured colorimetrically.Results: This study finds that maximum number of patients in both the control and study group had hemoglobin in the range of 16.3-17.3 gm/dl. The difference was not statistically significant. P value>0.05.Conclusions: Hematological changes observed early after delivery can determine the duration of hypoxemia (acute versus chronic) Perinatal anemia causing moderate to severe perinatal asphyxia is associated with a higher risk for neonatal mortality. All survivors with perinatal anemia, however, showed no abnormalities in neurodevelopment in contrast to children who were born asphyxiated due to various another causes. The underlying pathophysiological mechanism for the favorable NDO in the perinatal anemia group needs further elucidation.
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Alkattan, Abdullah N., Ahmed S. Alkhalifah, and Eman A. Alsalameen. "The Effect of Glycated Hemoglobin on the Prognosis of Diabetic Patients: A Cross-Sectional Observational Study." Saudi Journal of Internal Medicine 9, no. 1 (2019): 5–11. http://dx.doi.org/10.32790/sjim.2019.9.1.2.
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Objectives: Diabetes mellitus is a chronic metabolic disorder characterized by elevation of blood glucose and a high percentage of glycated hemoglobin A1c. Elevated hemoglobin A1c percentage of more than 7% will result in high production of advanced glycation end-products. Th e elevated level of advanced glycation end-products in diabetic patients means a high risk for diabetic complications. Th e primary endpoint was to evaluate the hemoglobin A1c levels among diabetic patients and its effect on the prognosis of this metabolic disease in all regions inside Saudi Arabia.
 Methods: Th is was a cross-sectional observational study conducted between March and August 2018. Th e study was done by using a questionnaire containing nine questions which planned to involve at least 390 diabetic patients.
 Results: Six hundred and ninety-four diabetic patients from Saudi Arabia had answered the nine-question questionnaire about hemoglobin A1c percentage and prognosis of diabetes. Th e mean age of these patients is 43.4 years old and most of those patients (75.5%) were visiting governmental hospitals. Th e number of diabetic patients having hemoglobin A1c less than 7% are 259 patients with hemoglobin A1c mean 6.66% + 3.33%, however, there are 435 patients having hemoglobin A1c more than 7% with mean equals 7.75% + 1.2%, the difference between them is statistically significant (P value < 0.0001).
 Conclusion: Th e glycated hemoglobin of diabetic patients in all regions of Saudi Arabia was significantly elevated and uncontrolled based on most diabetic guidelines and significantly affects the prognosis by causing diabetic complications especially cardiovascular diseases.
Dissertations / Theses on the topic "Hemoglobin percentage"
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Brachmann, Steffi. "Wertigkeit ausgewählter Eisenstoffwechselparameter im Ausdauersport." Doctoral thesis, Humboldt-Universität zu Berlin, Philosophische Fakultät IV, 2011. http://dx.doi.org/10.18452/16304.
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Einleitung: Eisenmangel ist ein häufiges Problem bei Ausdauersportlern, da dieser die Leistungsfähigkeit einschränken und zu einer Blutanämie führen kann. Von den klassischen Eisenstoffwechselparametern sind nur wenige geeignet, den tatsächlichen Eisenstatus anzuzeigen, da sie durch sportliche Aktivität per se beeinflusst werden können. In der Studie wird die Wertigkeit moderner Eisenstoffwechselparameter im Ausdauersport untersucht. Ergebnisse und Diskussion: Der Hämoglobingehalt der Retikulozyten (CHr) und der prozentuale Anteil der hypochromen Erythrozyten (% HYPO) bleiben als moderne Parameter der Eisenstoffwechseldiagnostik auch nach regenerativen, extensiven sowie intensiven Ausdauerbelastungen konstant. Sie zeigen somit unbeeinflusst von der (Ausdauer-)Sportart als auch von der Belastungsdauer und –intensität die aktuelle Eisenversorgung der Erythropoese im Knochenmark an. Als Monitoringparameter im Rahmen einer Eisensubstitution sind der CHr sowie der prozentuale Anteil hypochromer Retikulozyten sensible Parameter, mit denen sich schnell und zuverlässig die Effektivität einer oralen Eisensubstitution nachweisen lässt. Der Eisenstatus kann durch die alleinige Bestimmung des CHr bzw. des % HYPO nicht exakt ermittelt werden. Im Gegensatz zum Einsatz bei klinischen Fragestellungen können sie zu diesem Zeitpunkt in der Sportmedizin allenfalls nur ein ergänzender Parameter in der Differentialdiagnostik eines Eisenmangels sein. Die für Ausdauersportler ermittelten Referenzwerte liegen bei 28,8-35,9 pg für den CHr und bei 0-0,5 % für die hypochromen Erythrozyten. Ein belastungsbedingter Anstieg des Eisen-regulierenden Hormons Hepcidin könnte auf Grund seiner inhibitorischen Wirkung auf die intestinale Eisenabsorption sowie auf die Freisetzung von Eisen aus den Makrophagen zur Entwicklung von Eisenmangel-zuständen führen. Die Entwicklung von Hepcidin-Antagonisten könnte in Zukunft therapeutische Anwendungen finden.<br>Introduction: Athletes are commonly diagnosed with iron deficiency, particularly those involved in endurance sports. It often not only decreases athletic performance but also contributes to the development of anaemia. Many biochemical markers are used to evaluate body iron stores but some of them are affected by physical exercises. This study was designed to investigate new haematological parameters in endurance athletes. Results and discussion: Reticulocyte hemoglobin content (CHr) and percentage of hypochromic red cells (% HYPO) were highly stable in athletes subjected to varying physical loads. Furthermore, they were neither affected by different forms of endurance sports nor by their duration and intensity. These modern indices are able to reflect the availability of iron during erythropoiesis at all times. In the early prediction of response to oral iron supplementation, the reticulocyte indices CHr and % HYPOr (percentage of hypochromic reticulocytes) are the most sensitive parameters. However, it is not possible to assess the iron status in athletes by CHr and % HYPO alone. In contrast to other clinical cases they can only be an additional parameter in the differential diagnosis of iron deficiency. The calculated reference range for endurance athletes are 28,8 - 35,9 pg for CHr and 0-0,5 % for % HYPO. As the iron-regulating hormone hepcidin is inhibiting the absorption of iron from the diet at the site of the duodenal enterocytes and blocking the release of iron from macrophages that have collected senescent erythrocytes, an exercise induced up-regulation of hepcidin activity might potentially be a new mechanism causing iron deficiency in athletes. Therefore, the development of hepcidin antagonists could prove to be helpful with regard to therapeutic utilization.
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Siva, Rama Krishna V. "Towards Development Of Low Cost Electrochemical Biosensor For Detecting Percentage Glycated Hemoglobin." Thesis, 2012. https://etd.iisc.ac.in/handle/2005/2340.
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There is an ever growing demand for low cost biosensors in medical diagnostics. A well known commercially successful example is glucose biosensors which are used to diagonize and monitor diabetes. These biosensors use electrochemical analysis (electro analysis) as transduction mechanism. Electro analytical techniques involve application of electrical stimulus to the chemical/biochemical system under consideration and measurement of electrical response due to the oxidation and reduction reactions that occur because of the stimulus. They offer a lot of advantages in terms of sensitivity, selectivity, cost effectiveness and compatibility towards integration with electronics. Besides glucose, there are several biomolecules of significance for which electro analysis can potentially be used to develop low cost, rapid, easy to use biosensors. One such biomolecule is Glycated Hemoglobin (GHb). It is a post translational, non-enzymatic modification of hemoglobin with glucose and is a very good biomarker that indicates the average value of blood glucose over the past 120 days. It is always expresses as a percentage of total hemoglobin present in blood. Monitoring diabetes based on the value of percentage Glycated hemoglobin is advantageous as it gives an average value of glucose unlike plasma glucose values which vary a lot on a day to day basis depending on the dietary habits and the stress levels of the individual. This thesis is focused on the development of a low coat, easy to use, disposable sensor for measuring percentage Glycated hemoglobin.
The first challenge in developing such a sensor is isolation of hemoglobin. Unlike glucose which is present in blood plasma (liquid content of blood), hemoglobin resides inside red blood cells also known as erythrocytes. O isolate hemoglobin, these cells have to be broken or lysed. All the existing approaches rely on mixing blood with lysing reagents to lyse erythrocytes. Ideal biosensors should be devoid of liquid reagents. Keeping this in perspective, in this thesis, this challenge is addressed by developing two entirely buffer/reagentless techniques to lyse erythrocytes and isolate hemoglobin. In the first technique, cellulose acetate membranes are embedded with lysing reagents and are used for lysing reagents and are used for lysing application. In the second techniques, commercially available nylon mesh nets are modified with lysing reagents to lyse and isolate hemoglobin. These membranes or mesh nets can be easily integrated on top of a disposable strip.
After isolating hemoglobin, the next challenge is to selectively detect Glycated hemoglobin. Boronic acid conjugates are known to bind Glycated hemoglobin. Using this principle, a new composite is sysnthesized to specifically detect glc\ycated hemoglobin. The composite (GO-APBA) is a result of functionalization of Graphene Oxide (GO) with 3-aminophenylboronic acide (APBA). Detection of Glycated hemoglobin is achieved by modifying screen printed electrode strips with the synthesized compound, thus taking a step forwards achieving the objective.
Since Glycated hemoglobin is always expressed as a percentage of hemoglobin, the next challenge is to detect total hemoglobin. In this thesis a low cost way of detecting hemoglobin is achieved by using GO modified or surfactant modified screen printed electrode strips. Furthermore, the potential interferences that blood plasma can cause in these measurements are eliminated with the help of permselective coatings.
Thus using the technologies developed in this thesis, measurements of percentage Glycated hemoglobin can be potentially made on handheld electronic devices akin to glucose meters by using just a drop of blood.
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Siva, Rama Krishna V. "Towards Development Of Low Cost Electrochemical Biosensor For Detecting Percentage Glycated Hemoglobin." Thesis, 2012. http://etd.iisc.ernet.in/handle/2005/2340.
Full textAbstract:
There is an ever growing demand for low cost biosensors in medical diagnostics. A well known commercially successful example is glucose biosensors which are used to diagonize and monitor diabetes. These biosensors use electrochemical analysis (electro analysis) as transduction mechanism. Electro analytical techniques involve application of electrical stimulus to the chemical/biochemical system under consideration and measurement of electrical response due to the oxidation and reduction reactions that occur because of the stimulus. They offer a lot of advantages in terms of sensitivity, selectivity, cost effectiveness and compatibility towards integration with electronics. Besides glucose, there are several biomolecules of significance for which electro analysis can potentially be used to develop low cost, rapid, easy to use biosensors. One such biomolecule is Glycated Hemoglobin (GHb). It is a post translational, non-enzymatic modification of hemoglobin with glucose and is a very good biomarker that indicates the average value of blood glucose over the past 120 days. It is always expresses as a percentage of total hemoglobin present in blood. Monitoring diabetes based on the value of percentage Glycated hemoglobin is advantageous as it gives an average value of glucose unlike plasma glucose values which vary a lot on a day to day basis depending on the dietary habits and the stress levels of the individual. This thesis is focused on the development of a low coat, easy to use, disposable sensor for measuring percentage Glycated hemoglobin.
The first challenge in developing such a sensor is isolation of hemoglobin. Unlike glucose which is present in blood plasma (liquid content of blood), hemoglobin resides inside red blood cells also known as erythrocytes. O isolate hemoglobin, these cells have to be broken or lysed. All the existing approaches rely on mixing blood with lysing reagents to lyse erythrocytes. Ideal biosensors should be devoid of liquid reagents. Keeping this in perspective, in this thesis, this challenge is addressed by developing two entirely buffer/reagentless techniques to lyse erythrocytes and isolate hemoglobin. In the first technique, cellulose acetate membranes are embedded with lysing reagents and are used for lysing reagents and are used for lysing application. In the second techniques, commercially available nylon mesh nets are modified with lysing reagents to lyse and isolate hemoglobin. These membranes or mesh nets can be easily integrated on top of a disposable strip.
After isolating hemoglobin, the next challenge is to selectively detect Glycated hemoglobin. Boronic acid conjugates are known to bind Glycated hemoglobin. Using this principle, a new composite is sysnthesized to specifically detect glc\ycated hemoglobin. The composite (GO-APBA) is a result of functionalization of Graphene Oxide (GO) with 3-aminophenylboronic acide (APBA). Detection of Glycated hemoglobin is achieved by modifying screen printed electrode strips with the synthesized compound, thus taking a step forwards achieving the objective.
Since Glycated hemoglobin is always expressed as a percentage of hemoglobin, the next challenge is to detect total hemoglobin. In this thesis a low cost way of detecting hemoglobin is achieved by using GO modified or surfactant modified screen printed electrode strips. Furthermore, the potential interferences that blood plasma can cause in these measurements are eliminated with the help of permselective coatings.
Thus using the technologies developed in this thesis, measurements of percentage Glycated hemoglobin can be potentially made on handheld electronic devices akin to glucose meters by using just a drop of blood.
Book chapters on the topic "Hemoglobin percentage"
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Febriani, Wiwi, Ramadhana Komala, Dian Isti Angraini, Sofyan Musyabiq Wijaya, and Eka Putri Rahmadhani. "Body Mass Index, Waist Circumference, and Body Fat Percentage as Predictors of Hemoglobin Status in Adolescents Girl." In Advances in Health Sciences Research. Atlantis Press International BV, 2024. https://doi.org/10.2991/978-94-6463-604-8_12.
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Christopherson, Heather, and Ettore Crimi. "Mixed Venous Oxygen Saturation." In Advanced Anesthesia Review, edited by Alaa Abd-Elsayed. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197584521.003.0003.
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Abstract Mixed venous oxygen saturation (SvO2) is the percentage of oxygenated hemoglobin in the blood returning to the right side of the heart. SvO2 reflects the balance between oxygen delivery and oxygen consumed by tissues. Normally, SvO2 is 65%–75%. SvO2 can be measured with intermittent blood samples from the pulmonary artery or continuously with the use of oximetric catheters. Determinants of SvO2 are cardiac output, hemoglobin concentration, arterial oxygen saturation, and oxygen consumption. A decrease in oxygen delivery (e.g., cardiogenic shock, anemia, hypoxemia) or increase in oxygen demand (e.g., hyperthermia, shivering, malignant hyperthermia) causes a drop in SvO2. An increase in oxygen delivery (e.g., increased cardiac output, hyperoxia) and decrease in oxygen demand (e.g., hypothermia, anesthesia) cause high SvO2 values. SvO2 in combination with other clinical information can help to identify global tissue hypoxia during the perioperative period and in critically ill patients.
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Biswas, Dr Amit Kumar. "AN EFFECTIVE AUTOMATIC RECOGNITION METHOD OF SICKLE CELLS IDENTIFICATION IN THE BLOOD SMEAR." In Futuristic Trends in Computing Technologies and Data Sciences Volume 3 Book 8. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bkct8p2ch1.
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Red blood cells carry oxygen and transport it to all body parts through a connective tissue known as blood. One of the abnormalities of RBC is anemia, known as sickle cell, and it is one kind of blood disorder. An RBC usually is in a disk shape, but it changes its disk shape due to improper hemoglobin protein content to form a sickle cell structure, and it is a disease.In this disease, the red blood cell shape is changed to crescent-shaped, called sickle-shaped. In India, specifically in Chhattisgarh, it is a deliberate problem of disorder very much common among backward classes, including scheduled tribes and scheduled castes.This disease is the highest percentage in the surname Sahu, Dewangan, Gond, Mahar, Halba, and Kurmi. Among various methods of blood cell count, manual counting is the most commonly used method. But manual counting mainly depends on the technical person. Therefore, an image processing-based effective object detection method to automatically detect and count the sickle-shaped cells present in the blood smear is proposed in this paper. The proposed method gives 99.96% accuracy for sickle cell counting compared to manual and other existing counting methods.
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Segal, Sheldon J., and Luigi Mastroianni. "Can men safely use AST?" In Hormone Use in Menopause & Male Andropause. Oxford University PressNew York, NY, 2003. http://dx.doi.org/10.1093/oso/9780195159745.003.0017.
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Abstract An accurate term to describe the hormonal changes of older men is “partial androgen deficiency.” Androgens stimulate male anatomical structures such as the prostate gland and also effect other masculine characteristics. These hormones also influence many general metabolic functions, including bone mineral density, maintenance of muscle cells, and the hemoglobin content of blood. Strictly speaking, androgens cannot be called “male hormones” because the ovaries and adrenal glands of women also produce them. There are several androgenic hormones produced by the body or that chemists can synthesize in the test tube, but the obvious androgen to use for male replacement therapy is testosterone, the principal hormone produced by the testis. The level of testosterone production decreases in men as they age. By the time a man reaches 70 years of age, his level of biologically active testosterone has fallen to half its level at age 20. Whether this is the defining cause of aging changes, however, remains controversial. Although studies of large numbers of men show that in the general population, free testosterone (the component of the circulating hormone that is biologically active) concentrations decline by up to 1% per year, some doctors believe that a falling testosterone level is a measure of ill health in aging men. This point of view suggests that the percentage of healthy older men who need testosterone therapy is low.
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Swain, Nicole F., and Scott W. Powers. "Pain Management of Sickle Cell Disease." In Comprehensive Handbook of Childhood Cancer and Sickle Cell Disease. Oxford University Press, 2006. http://dx.doi.org/10.1093/oso/9780195169850.003.0036.
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Acute and chronic pain episodes are common experiences for many individuals living with sickle cell disease (SCD). The management of pain related to SCD is primary palliative and includes pharmacological, nonpharmacological, and preventive therapies (Ballas, 2002). This chapter focuses on issues relevant to the assessment and treatment of sickle cell pain in primarily pediatric populations, although some of the adult literature is reviewed, particularly as it relates to children and adolescents. SCD is a hereditary disorder. The disorder primarily affects people of Caribbean and African origin in addition to a small percentage of people of Indian, Mediterranean and Middle Eastern descent (National Association of Health Authorities and Trusts–NAHAT, 1991). SCD is also prevalent in Hispanic and Latino populations. Red blood cells containing sickle hemoglobin become rigid. These cells then become elongated and “sickled” in shape, which makes it very difficult for the sickle cells to move smoothly and flow through microcirculation (Morrison & Vedro, 1989). Symptoms of SCD include chronic anemia, susceptibility to infection, and vaso-occlusive crises or vaso-occlusive episodes (VOEs), resulting in severe pain that can last hours to weeks (Wang, George, & Wilimas, 1988). This vaso-occlusion is caused when sickle cells are unable to flow through arteries, capillaries, arterioles, and other blood vessels and as a result obstruct blood flow. This sickling can occur anywhere in the body, including fingers, arms, ribs, abdomen, and organs such as the brain and eyes (Morrison & Vedro, 1989), but it most commonly occurs in the spleen, bones, and joints (Elander & Midence, 1996). These restrictions in blood flow result in severe pain. In addition, other major clinical problems arise from SCD, including stroke, acute chest syndrome, aseptic necrosis of the hips and shoulders, infections, anemia, leg ulcers, and priapism (Serjeant, 1992). Acute chest syndrome is a significant concern and is the leading cause of mortality in both children and adults with SCD (Platt et al., 1994). Stroke tends to be the most disabling condition and is also a significant cause of death. Stroke in SCD patients accounts for approximately 6% of deaths related to sickle cell disease (Platt et al., 1994).
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Demirci, Cami, Vered Lewy-Weiss, and Mark Sperling. "Case 38: Challenging Insights from Albuminuria Early in the Course of Disease." In Diabetes Case Studies: Real Problems, Practical Solutions. American Diabetes Association, 2015. http://dx.doi.org/10.2337/9781580405713.38.
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The patient was a Caucasian woman diagnosed with type 1 diabetes (TID) at the age 11 years when she presented in mild DKA, pH of 7.20, and hemoglobin A1c (HbA1c) 11.5%. Testing for the presence of islet cell antibodies was not performed. She responded well to treatment, initially consisting of basal and bolus injections, and after 2 years, using insulin pump therapy, she maintained excellent metabolic control with all HbA1c values <6.5% after stabilization (Fig. 38.1). Her HbA1c values were still in the near normal range at 5.8% (N = 4.3–6.1%) several years after diagnosis, and total daily insulin varied from 0.5 to 0.7 units/kg/day. Her general health was excellent with normal systolic and diastolic blood pressures; height was at the 50th percentile, weight was at the 90th percentile with BMI in 95–97th percentile. Annual tests of thyroid function and lipid profile were normal. Because “dipstick” urine for protein was positive 3 years after diagnosis, she provided an overnight urine collection for measurement of albumin excretion rate, which was 156.8 μg/min (normal = <21 μg/min). A split day-night urine collection showed that albumin excretion was 143 mg/dL during the day and 10.6 mg/dL at night. Normal nocturnal albumin excretion is up to 1.9 mg/dL, so the nocturnal albumin excretion was increased. Her albumin-to-creatinine ratio was 1,254.4 mg/g during the day and 87.6 mg/g at night, with a normal range being 15–37 mg/g. These findings were consistent with both daytime macroalbuminuria and nighttime microalbuminuria.
Conference papers on the topic "Hemoglobin percentage"
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Yushkov, Boris Germanovich, and Svetlana Alexandrovna Brilliant. "HEMOGLOBIN ISOFORMS AND ERYTHROCYTE HETEROGENEITY." In NEW TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. Institute of information technology, 2021. http://dx.doi.org/10.47501/978-5-6044060-1-4.46.
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The work shows changes in the ratio of blood hemoglobin isoforms and of bone marrow their distribution by types of erythrocytes. One erythrocytes carries two isoforms of hemoglobin. Erythrocytes with a lower molecular weight contain a lower percentage of acid- and alkali-resistant properties.
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Dewi, Ratna Candra, Nanda Rimawati, and Lutfhi Abdil Khuddus. "Nutritional Status, Body Fat Percentage, Hemoglobin Level and Physical Fitness in A Football Athlete." In The 2nd International Symposium of Public Health. SCITEPRESS - Science and Technology Publications, 2017. http://dx.doi.org/10.5220/0007515204190424.
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S, Renukalatha, J. Senthil Kumar, A. Sangeetha, M. Hema, Ashok Kumar, and Ramesh Singh Rawat. "Determination of Hemoglobin Percentage Through K-Means Algorithm and Image Processing for White Blood Cell Diagnosis." In 2023 4th International Conference on Smart Electronics and Communication (ICOSEC). IEEE, 2023. http://dx.doi.org/10.1109/icosec58147.2023.10275883.
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Cincović, Marko, Jože Starič, Jožica Ježek, et al. "Complete blood count in cows in the peripartal period and the relationship to the indicators of metabolic stress." In Zbornik radova 26. medunarodni kongres Mediteranske federacije za zdravlje i produkciju preživara - FeMeSPRum. Poljoprivredni fakultet Novi Sad, 2024. http://dx.doi.org/10.5937/femesprumns24006c.
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Lactation and metabolic rearrangement significantly influence hematological parameters. The red bloodline of early lactation cows is characterized by hypochromic changes in erythrocytes and a reduced number of erythrocytes. The reduced concentration of hemoglobin is linked to milk production, since a higher hemoglobin concentration was found in heifers (which are not naturally lactating). The number of neutrophils was the highest in the first week after parturition, while the number of lymphocytes was the lowest in the same period, so the neutrophil:lymphocyte index was the highest in this period. The number of eosinophils increased slightly during the experimental period, while the number of monocytes was the highest in the first week and then decreased. Such changes in the differential white line occur as a consequence of the action of acute stress and a sudden jump in the concentration of cortisol, which has shown its effect on immune cells. In white cattle, NEFA as an indicator of metabolic stress leads to a drop in the total number of leukocytes, and cows classified according to the NEFA and cortisol criteria show an increased percentage of neutrophils, a decreased percentage of lymphocytes, an increased N:L ratio, a decreased percentage of eosinophils and an increased percentage of monocytes. The influence of cortisol on the parameters of the blood count only exists in the first week because the concentration of cortisol rises sharply and then sharply decreases in the first few days after calving, while the concentration of NEFA rises slightly and is often persistent in the first weeks of lactation, which indicates a negative energy balance . In the study of the influence of metabolic stress indicators on the value of the parameters of the blood count, it was found that the classification of cows according to the values of NEFA and cortisol gives significant differences in the red and white bloodlines, which confirms the importance of peripartum metabolic stress caused by parturition and lactation in the response of the blood count in cows.
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Saed Doosh, Kifah, Hind K. Ali, Baidaa Hatem Kadhem, and Wurood Fawzi Ahmed. "Manufacture of Therapeutic Yogurt Enriched with Iron and Study Its Role in Some Health Indicators of White Mice." In I. International Rimar Congress of Pure, Applied Sciences. Rimar Academy, 2024. http://dx.doi.org/10.47832/rimarcongresspas01-2.
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The present investigation was carried out with the intention of examining the effects of treating anemia by supplementing milk used for producing yogurt with both encapsulated and non-encapsulated iron. The current study included preparing three different yoghurt treatments: the first was produced as a positive control treatment (C+) with no additions, the second consisted of the addition of non-encapsulated iron to milk that was prepared for the manufacturing process with a concentration of 4 mg/100 ml (T1 treatment), and the third was added to the milk prepared for its manufacture encapsulated iron with sodium alginate at a concentration of 4 mg/100 ml to represent T2 treatment. Three groups of experimental mice in which induced anemia were induced, each group was fed on one of the three types of yogurt mentioned above in addition to a fourth group of mice they were left to feed on the standard diet to represent the negative control C -, The effect of iron fortification yogurt on health indicators related to anemia was studied, in addition to the effect on the rate of weight gain. The results showed that feeding on the standard diet and yogurt fortified with encapsulated iron significantly affected the rate of weight gain of laboratory animals more than yogurt fortified with non-encapsulated iron. Additionally, as compared to the control group C+ fed non-ironfortified yogurt, C-, and T1, there was an increase in the concentration of transferrin and ferretin compounds, a percentage of iron in the serum, the average volume of red blood cells, the average amount of hemoglobin present in them, an analysis of the mean concentration of hemoglobin per globular, and platelet examination.
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Hashim Oubid, Sarah. "Evaluation of Serum level of Ghrelin, Adiponectin and Cholecystokinin and some Hematological variables in Giardia lamblia Infected Patients in Kirkuk city." In II. International Rimar Congress of Pure and Applied Sciences. Rimar Academy, 2024. https://doi.org/10.47832/rimarcongresspas02-04.
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Background: The parasite G . lamblia is one of the most widespread intestinal parasites that infect humans throughout the world, causing giardiasis. It is a single-celled parasite that has attracted scientific interest not only for its spread throughout the world, but for its internal membrane system as well. Therefore, the research aimed to evaluate the levels of Ghrelin, adiponectin and Cholecystokinin and some hematological variables in patients infected with the G. lamblia . Objective: The current study was designed to evaluation of G. lamblia infection effects on some biomarkers such as ghrelin , adiponectin and Cholecystokinin . Methods: The study was conducted on 80 patients infected with G. lamblia and 300 healthy people (control group), who attended the Al-Jumhuri general hospital of Kirkuk city from 1/4/2024-15/6/2024. The results : The results showed a significant (P<0.05) elevated in serum concentration of (Adiponectin , Cholecystokinin , White blood cellWBC , Erythrocyte sedimentation rate -ESR , C-Reactive protein- CRP , IgM ) and a significant decrease in concentration of ( Ghrelin , Packed cell volume-PCV , Hemoglobin-Hb , IgA, Ig G ) in G. lamblia infected patients compered healthy people. Prevalence rate :- The result showed that the infection rate with the G . lamblia parasite was 80 samples (26.6%), while 220 samples (73.4%) were uninfected. In terms of gender, the results showed that the highest percentage was for females, at 62.5%, compared to males, which recorded the lowest percentage, as It was 37.5%. Conclusion: Ghrelin , adiponectin and cholecystokinin and some variables are important physiological and hematological biomarkers that can support the diagnosis of G. lamblia parasite.
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Tahseen Taha AL-TAEE, Nidhal. "EFFECT OF FATTY EXTRACT OF AZOLLA PLANT WITH DIFFERENT SOLVENTS ON HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS OF COMMON CARP CYPRINUS CARPIO L." In VI.International Scientific Congress of Pure,Applied and Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress6-51.
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The study was conducted in the fish laboratory of the Department of Animal Production in the College of Agriculture and Forestry / the University of Mosul. The experiment included feeding common carp fish using ten experimental diets containing Azolla plant extract at percentages (0.5%, 1%, 1.5%) of each solvent, ether, acetone, and ethanol, and the control was free of additives. Glass tanks were used in the growth experiment of carp fish for a period of 49 days. The results of the statistical analysis showed that the average hemoglobin concentration and the percentage of the volume of compacted blood cells were significantly (P≤ 0.05) higher in the two treatments of fish with fatty extract (petroleum ether 0.5% and acetone 0.5%) than the control treatment and the treatment of fish with fatty extract Acetone for the two concentrations (1 and 1.5) %, noting the arithmetic differences between the other treatments. Best results were found for adding the fatty extract with different solvents to fish diets on total protein, albumin, and globulin in the acetone treatment (05%) and also significantly (P≤ 0.05) the total protein in the ethanol treatment (1.5%) and the albumin increased in the ether treatment. Petroleum (0.5%), acetone 1%, and ethanol (0.5% and 1.5%). A significant decrease was observed in the average concentration of glucose, cholesterol, and triglycerides in the blood serum of fish treated with fatty extract and according to solvents (ethanol 0.5% and 1%) for the average concentration of glucose, and acetone (0.5% and 1.5%) for the average of cholesterol and triglycerides, respectively. A significant decrease was observed in the average concentration of the aspartate transporter enzyme and the amino acid Lanin transferase enzyme in the serum of fish treated with the fatty extract (petroleum ether 0.5% and acetone 1%), respectively.
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Saed DOOSH, Kifah, Shaymaa saady LAFTA, Raed Mohammed Khalaf AL-ZAIDI, and Sharaf Ali ALSHAIKH. "STUDY OF SOME HEALTH INDICATORS OF FEEDING ON WHITHE SOFT CHEESE FORTIFIED WITH SELENIUM IN LABORATORY WHITH MICE." In VII. INTERNATIONAL SCIENTIFIC CONGRESSOF PURE,APPLIEDANDTECHNOLOGICAL SCIENCES. Rimar Academy, 2023. http://dx.doi.org/10.47832/minarcongress7-12.
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Selenium (Se) is one of the rare and necessary elements with multiple and important biological applications, especially its effective role in the treatment of many chronic diseases and cancers, and that its deficiency causes health problems, and for this the current study was conducted and aimed to manufacture Iraqi soft cheese supported with two levels of Se, which are 100 and 200 μg / 1 kg of coagulame. represented by T1 and T2 treatments respectively, which used in a feeding of laboratory mice Which caused an artificial rise in the level of blood fats (Hyperlipidemia) in order to evaluate the feeding of selenium-fortified cheese on some nutritional and health indicators ,the most important results that were obtained: Se limited the daily weight gain and final weight gain of experimental animals fed a diet rich in fat with daily oral doses of selenium-fortified cheese treatment T1 and T2, respectively, compared with C+ positive control group mice fed a diet rich in fat without se and very close to C-negative control mice fed a standard diet only. Se also reduced the levels of total cholesterol TC, triglycerides TG, bad fats Low-Density Lipoprotein LDL and Very-LowDensity Lipoprotein VLDL, and raised the values of good fats High-Density Lipoprotein HDL significantly at (P≤0.05). The two groups T1 and T2 outperformed in some indicators even on the C- . Se reduced the glucose content in the blood and the levels of liver enzymes GOT, GPT and ALP. And improved the activity and effectiveness of the enzyme glutathione peroxidase and the efficiency of the immune system by increasing the total numbers of white blood cells and increasing the level of hemoglobin and the percentage of the volume of compressed cells.
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Sugimoto a, Junya, and Hiroshi Hagiwara b. "Effect of fNIRS on Physiological Index and Performance Under Vibratory Stimulus." In Applied Human Factors and Ergonomics Conference. AHFE International, 2019. http://dx.doi.org/10.54941/ahfe100217.
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Many traffic accidents are caused by human error. In order to help prevent human such error, we investigated brain hemodynamics in both the frontal and the somatosensory areas by functional near-infrared spectroscopy (fNIRS), electrocardiogram (ECG), and the following two types of task performance with vibratory stimulation: a Tracking task and the Stroop test. To evaluate changes in oxygenated hemoglobin concentration (oxyHb), we used δoxyHb as previously defined (H. Iwasaki: Availability and future prospects of functional near-infrared spectroscopy in usability evaluation, Human Factors and Ergonomics). Briefly, the waveform data of oxyHb are passed through a differential filter. A sum of more than zero is defined as a positive component, whereas a sum of less than zero is defined as a negative component. δoxyHb is defined as a positive component minus a negative component. δoxyHb > 0 indicates an increasing trend of oxyHb and δoxyHb < 0 indicates a decreasing trend of oxyHb. Our results show that tracking error and the variance of tracking error were reduced when vibratory stimulation was present. Marginally statistically significant (p < 0.1) differences for both tracking and Stroop indices were observed when comparing measures with and without vibratory stimulation. These results suggest that subjects were able to track targets more stably with than without vibratory stimulation. On the other hand, performance on the Stroop test (reaction time, variance of Stroop test, and percentage of correct answers) was not affected by vibratory stimulation. ECG HF (high frequency) in both tasks was lower with than without vibratory stimuli. ECG LF (low frequency)/HF in both tasks was higher with than without vibratory stimuli. The results of HF and LF/HF stimulation imply the predominance of both the sympathetic nervous system during vibratory stimulation and the parasympathetic nervous system with no stimulus. δoxyHb showed differences in the somatosensory area during the Tracking task between vibratory stimulation and no stimulation. In summary, presentation of vibratory stimuli improved performance in the Tracking task. Therefore, use of vibratory stimulation during driving may decrease traffic accidents caused by human error.
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Lacerenza, M., V. Rossi, S. Zanelli, et al. "Cerebral and peripheral tissue oximetry in pediatric population: establishing expected values in TD-NIRS measurements." In Optics and the Brain. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/brain.2024.bw3c.1.
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A large cohort of pediatric subjects has been studied to define percentile distribution of oxygen saturation and hemoglobin concentration in prefrontal cortex and upper arm via time-domain near-infrared spectroscopy. Results on the first 240 subjects are presented.
Reports on the topic "Hemoglobin percentage"
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Viksna, Ludmila, Oksana Kolesova, Aleksandrs Kolesovs, Ieva Vanaga, and Seda Arutjunana. Clinical characteristics of COVID-19 patients (Latvia, Spring 2020). Rīga Stradiņš University, 2020. http://dx.doi.org/10.25143/fk2/hnmlhh.
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Data include following variables: Demographics, epidemiological history, comorbidities, diagnosis, complications, and symptoms on admission to the hospital. Also, body’s temperature and SpO2. Blood cells: white cells count (WBC), neutrophils (Neu), lymphocytes (Ly), eosinophils (Eo) and monocytes (Mo), percentages of segmented and banded neutrophils, erythrocytes (RBC), platelet count (PLT), hemoglobin (Hb), and hematocrit (HCT); Inflammatory indicators: erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP); Tissue damage indicators: alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and troponin T (TnT); Electrolytes: potassium and sodium concentration; Renal function indicators: creatinine and glomerular filtration rate (GFR); Coagulation tests: D-dimer, prothrombin time, and prothrombin index on admission to the hospital.