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Journal articles on the topic 'Hemorrhagic fever with kidney syndrome'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Zivkovic, Milovan, Zoran Todorovic, Oligica Gajovic, Ljiljana Nesic, and Zeljko Mihailovic. "Parameters for assessing the severity of clinical presentation of hemorrhagic fever with kindey syndrome." Medical review 63, no. 5-6 (2010): 361–65. http://dx.doi.org/10.2298/mpns1006361z.

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Introduction. Hemorrhagic fever with kidney syndrome is an acute infectious disease of the zoonotic character, which is characterized by the sudden beginning, high temperature, distinct hemorrhagic syndrome and symptoms and signs of the acute kidney insufficiency. Hemorrhagic fever with kidney syndrome can have mild, moderate and severe clinical picture and the mortality ranges from 5%-15% in our area. The pupose of this study was to try to present criteria on the basis of which it would be possible to forsee, on time, the severity of the clinical picture and to recognize the patient with the

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Khasanova, G. M., K. M. Manakhov, E. Yu Benderskaya, et al. "Features of renal blood supply in patients with severe course of hemorrhagic fever with renal syndrome." Infekcionnye bolezni 22, no. 4 (2024): 26–31. https://doi.org/10.20953/1729-9225-2024-4-26-31.

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Objective. Evaluation of ischemic kidney damage in hemorrhagic fever with renal syndrome of severe severity using ultrasound techniques and urine gas analysis. Patients and methods. Fifty patients at the Republican Clinical Infectious Diseases Hospital, Izhevsk, aged 40.5[33.0;46.0] years in 2022–2023 with a diagnosis of HFRS and 42 patients with HFRS at the Republican Clinical Infectious Diseases Hospital, Ufa, aged 41.2[33.0;49.0] years in 2024 were examined. The diagnosis of hemorrhagic fever with renal syndrome, severity and complications were made in accordance with current clinical recom

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Popov, A. F., V. A. Ivanis, L. Y. Pereverten, and L. F. Sklyar. "Severe case of hemorrhagic fever with renal syndrome." Pacific Medical Journal, no. 2 (June 23, 2022): 94–96. http://dx.doi.org/10.34215/1609-1175-2022-2-94-96.

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Primorsky Region is an epidemic focus of hemorrhagic fever with renal syndrome , where the morbidity is caused by two orthohunts of the Hantaan virus (including its variant Amur) and Seoul. The average long-term morbidity rate in Primorsky Region for 10 years (2011-2020) accounted for 2.7 per 100 thousand people, (in some years up to 4.4 per 100 thousand people). The mortality rate made 3.2% (in 2018 – 9.1%). Distribution of the clinical forms of the disease for the last 10 years showed that moderate form of the disease is prevalent (66%), severe forms accounted for about 30% of all regional c

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Starostina, V. I., A. Zh Gilmanov, and G. R. Latypova. "Hemorrhagic fever with renal syndrome and leptospirosis: Differential diagnosis." Medical alphabet, no. 23 (November 7, 2023): 46–52. http://dx.doi.org/10.33667/2078-5631-2023-23-46-52.

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Hemorrhagic fever with renal syndrome and leptospirosis have similarities and differences in the clinical picture. Fever, intoxication, pronounced kidney damage and hemorrhagic syndrome are observed in both infections. The course of these diseases may be complicated by the development of infectious-toxic shock, acute renal failure, disseminated intravascular coagulation. Clinical manifestations of the syndrome of jaundice and meningitis may be observed in leptospirosis, but are not characteristic of hemorrhagic fever with renal syndrome. In leptospirosis, in contrast to hemorrhagic fever with

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R Gomes, Richmond. "Expanded Dengue Syndrome Presenting as Acute Pancreatitis." Clinical Medical Reviews and Reports 3, no. 9 (2021): 01–06. http://dx.doi.org/10.31579/2690-8794/098.

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Dengue is a painful, debilitating mosquito-borne disease(female mosquitoes of the Aedes genus, principally Aedes aegypti)caused by any one of four closely related dengue viruses.It is endemic in tropical and subtropical continent. World health organization (WHO) currently estimates there may be 50 -100 million dengue infections worldwide every year with over 2.5 billion people at risk of dengue. Symptomatic dengue virus infection may manifests as undifferentiated fever, classical dengue fever (with or without unusual hemorrhages), and dengue hemorrhagic fever(with or without shock). Expanded d

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GALIMOVA, SAIDA SH, NURIYA I. ABDRAKHMANOVA, IRINA D. SEBYAKINA, et al. "THROMBOCYTOPENIA AND C-REACTIVE PROTEIN AS MARKERS OF HEMORRHAGIC FEVER WITH RENAL SYNDROME, COMPLICATED BY ACUTE KIDNEY FAILURE." Bulletin of Contemporary Clinical Medicine 17, no. 6 (2024): 13–18. https://doi.org/10.20969/vskm.2024.17(6).13-18.

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Introduction. Hemorrhagic fever with renal syndrome is a common zoonotic disease that can lead to acute kidney failure in severe cases. Although there has been a lot of research on clinical and laboratory indicators, there are no specific markers to identify cases of hemorrhagic fever with renal syndrome, complicated by acute kidney failure. This study aims to examine platelet production and inflammatory factors in laboratory tests as potential markers for identifying this complication. Materials and Methods. 135 patients were examined. The group with mild to moderate disease consisted of 62 i

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Анисимова, T. Anisimova, Ефимова, and E. Efimova. "Residual syndrome in convalescents of hemorrhagic fever with renal syndrome." Journal of New Medical Technologies. eJournal 8, no. 1 (2014): 1–4. http://dx.doi.org/10.12737/6012.

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The outcomes of hemorrhagic fever with renal syndrome (HFRS) were analyzed in 55 patients who were under the supervision of a physician – infectious within one year after the disease. This issue has been studied in more detail by the example of Hantaan virus infection in the Far East, the effects of Puumala infection aren’t well understood, vigilance among physicians concerning the formation of chronic kidney disease in patients is lacking. However, it is proved that the peculiarities of the clinical course of HFRS are caused by a specific serotype of the virus. It is revealed that the leading

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Vincent, Agustinus, Bramantono -, Usman Hadi, and Muhammad Vitanata Arifijanto. "EXPANDED DENGUE SYNDROME." Current Internal Medicine Research and Practice Surabaya Journal 3, no. 1 (2022): 26. http://dx.doi.org/10.20473/cimrj.v3i1.32536.

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ABSTRACTDengue viral infection (DVI) is a debilitating arthropod-borne disease that has been rapidly spread in several regions of the world in recent years. The spectrum of disease varies from mild self-limiting illness to dengue fever (DF) to more severe and fulminating forms, i.e., dengue hemorrhagic fever (DHF), dengue shock syndrome (DSS),and expanded dengue syndrome (EDS). The pathogenesis of EDS is not clear amid lack of studies on animal models. In the absence of in vitro experiments, disease spectrum is difficult to be elucidated and mimicked for humans.Recent advances on research on a

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Kim, S. H., S. Kim, J. S. Lee, et al. "Hemorrhagic fever with renal syndrome: MR imaging of the kidney." Radiology 175, no. 3 (1990): 823–25. http://dx.doi.org/10.1148/radiology.175.3.1971450.

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Hautala, Nina, Terhi Partanen, Anna-Maria Kubin, Heikki Kauma, and Timo Hautala. "Central Nervous System and Ocular Manifestations in Puumala Hantavirus Infection." Viruses 13, no. 6 (2021): 1040. http://dx.doi.org/10.3390/v13061040.

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Puumala hantavirus (PUUV), carried and spread by the bank vole (Myodes glareolus), causes a mild form of hemorrhagic fever with renal syndrome (HFRS) called nephropathia epidemica (NE). Acute high fever, acute kidney injury (AKI), thrombocytopenia, and hematuria are typical features of this syndrome. In addition, headache, blurred vision, insomnia, vertigo, and nausea are commonly associated with the disease. This review explores the mechanisms and presentations of ocular and central nervous system involvement in acute NE.

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Geraskin, M. Y., R. Y. Gorfinkel, L. V. Ivanova, and L. V. Chernyavskaya. "The state of the microflora of the colon in persons who have had hemorrhagic fever with renal syndrome." Kazan medical journal 72, no. 6 (1991): 470–71. http://dx.doi.org/10.17816/kazmj89552.

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In persons who have had hemorrhagic fever with renal syndrome (HFRS), destructive and functional disorders of the tubular apparatus of the kidneys persist for a long time, which can create prerequisites for the addition of a secondary infection and the development of pyelonephritis. Separately, the authors consider the intestinal microflora one of the possible sources of kidney infection, which is confirmed by the frequent detection of bactercuria in intestinal dysbiosis and the presence of dysbiosis in patients with pyelonephritis.

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Han, Yeon-Hee, and Chang-Seop Lee. "FDG PET/CT in Hantavirus Hemorrhagic Fever With Renal Syndrome." Clinical Nuclear Medicine 48, no. 12 (2023): 1073–75. http://dx.doi.org/10.1097/rlu.0000000000004915.

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Abstract A 58-year-old man with fever, myalgia, and dysuria was admitted to the hospital. Because of prolonged fever, FDG PET/CT was performed. Surprisingly, bilateral kidneys were rapidly enlarged for 5 days with the renal parenchyma showing intense hypermetabolism. FDG PET/CT demonstrated physiology of Hantavirus invading kidneys and causing nephritis. This case illustrates that FDG PET/CT could be the choice of image modality for diagnosis and treatment evaluation of patients suspected of hemorrhagic fever with renal syndrome. To the best of our knowledge, this is the first report of FDG PE

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BULATOVA, A. KH, I. M. KHAERTYNOVA, and V. G. SHAKIROVA. "Features of the course of hemorrhagic fever with renal syndrome in children of various ages." Practical medicine 20, no. 7 (2022): 57–60. http://dx.doi.org/10.32000/2072-1757-2022-7-57-60.

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Hemorrhagic fever with renal syndrome (HFRS) is the most common natural focal infection registered in the Republic of Tatarstan. Basically, HFRS affects people of working age, the proportion of children is 2.4%. The purpose was to study the clinical features of the HFRS course in children. Material and methods. We examined 40 children aged 1 to 17 years with HFRS hospitalized at the Republic Clinical Hospital in 2017–2021. All children were divided into 2 groups according to pubertal age: group 1 consisted of 12 children aged 0 to 8 years, group 2 consisted of 28 children aged 9 to 17 years. R

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Mocanu, Adriana, Ana-Maria Cajvan, Tudor Ilie Lazaruc, et al. "Hantavirus Infection in Children—A Pilot Study of Single Regional Center." Viruses 15, no. 4 (2023): 872. http://dx.doi.org/10.3390/v15040872.

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Background: Hantaviruses are infectious etiological agents of a group of rodent-borne hemorrhagic fevers, with two types of clinical manifestations in humans: hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). According to available statistics, the disease occurs mainly in adults, but the lower incidence in the pediatric population might also be related to a lack of diagnosis possibilities or even unsatisfactory knowledge about the disease. Materials and Methods: The purpose of this study was to evaluate the cases of hemorrhagic fever with renal syndrome diag

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Ivanov, Mikhail F. "The role of immune mechanisms in the pathogenesis of hemorrhagic fever with renal syndrome." Aspirantskiy Vestnik Povolzhiya 23, no. 3 (2023): 4–12. http://dx.doi.org/10.55531/2072-2354.2023.23.3.4-12.

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Hemorrhagic fever with renal syndrome (HFRS) is an acute natural focal disease of a viral nature. Its severity is determined by hemorrhagic phenomena, cytokine storm, kidney damage with the development of acute renal failure, and the possibility of death. HFRS is caused by viruses from the family Hantaviridae. Hantaviruses are characterized by the ability to infect endothelial and epithelial cells of the renal tubules, as well as innate immunity cells (neutrophils, monocytes, dendritic cells), which leads to both direct damage to the immune system and indirect through a violation of their func

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Noack, Danny, Maja Travar, Visnja Mrdjen, et al. "Serum Markers Associated with Disease Severity in a Bosnian Hemorrhagic Fever with Renal Syndrome Cohort." Viruses 14, no. 7 (2022): 1377. http://dx.doi.org/10.3390/v14071377.

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Puumala orthohantavirus (PUUV) is endemic in Europe and can cause hemorrhagic fever with renal syndrome (nephropathia epidemica). Disease features include fever, thrombocytopenia, and acute kidney injury (AKI). This retrospective cohort study of forty PUUV patients aims to characterize associations of serum immunological, hemostatic or kidney injury markers to disease severity. While interleukin-18 (IL-18) was significantly increased in severely thrombocytopenic patients (<100 × 109 platelets/L) compared to patients with higher platelet counts, RANTES was significantly decreased in these pa

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Khen Mikhael, Dominicus Husada, and Pudji Lestari. "Profile of Dengue Fever Complication in Infant at Tertiary Referral Hospital in East Java, Indonesia." Biomolecular and Health Science Journal 5, no. 1 (2022): 11–15. http://dx.doi.org/10.20473/bhsj.v5i1.34827.

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Introduction: Dengue virus infection is caused by the dengue virus and transmitted through the bites of infected Aedes aegypti or Aedes albopictus mosquitoes. The spectrum of clinical manifestations is varied from asymptomatic, undifferentiated fever, dengue fever, dengue hemorrhagic fever, dengue shock syndrome, to expanded dengue syndrome. Data from 2016 in Indonesia revealed that dengue virus infection is common in the population, with a total of 333.821 cases of dengue hemorrhagic fever. Methods: This was a descriptive study with a cross-sectional design. The subjects in this study were ch

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Islam, Quazi Tarikul, Homayra Tahseen Hossain, Md Abulkashem Khandaker, HAM Nazmul Ahasan, Maksudul Majumder, and Tajnuva Jabeen. "Dengue Expanded Syndrome: An unusual presentation." Bangladesh Journal of Medicine 29, no. 1 (2018): 45–47. http://dx.doi.org/10.3329/bjmed.v29i1.35408.

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Dengue fever is a mosquito borne viral infection found in tropic & sub-tropic regions. The symptomatic dengue infection follows an uncomplicated course; however, unusual manifestations of this disease are now being increasingly reported as expanded dengue syndrome which incorporates wide spectrum of uncommon presentation of this common disease which does not fall into either dengue shock syndrome or dengue hemorrhagic fever. We report a case of a 30 year old lady who presented with high grade fever, rash, diffuse abdominal pain & vomiting, who ultimately developed shock and features of

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Stulova, Mariуa V., Dmitrii Yu Konstantinov, Larisa L. Popova, Anna V. Lyubushkina, and German V. Nedugov. "Prediction of chronic kidney disease in patients with hemorrhagic fever with renal syndrome." Science and Innovations in Medicine 7, no. 1 (2021): 35–38. http://dx.doi.org/10.35693/2500-1388-2022-7-1-35-38.

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Aim to develop, using mathematical and statistical analysis of clinical, laboratory and instrumental data, a method for predicting the development of chronic kidney disease (CKD) in patients with hemorrhagic fever with renal syndrome (HFRS). Material and methods. 244 patients at the age from 18 to 50 years with a confirmed diagnosis of HFRS were examined. Patients were observed in the following periods: oliguric, polyuric, early (30th day of illness) and late (90th and 180th day of illness) convalescence. Clinical, laboratory and instrumental data, including computer photoplethysmography

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Manakhov, K. M., T. M. Kamenshchikova, O. E. Tsarenko, et al. "Features of hemorrhagic fever with renal syndrome with diabetes mellitus." Terapevticheskii arkhiv 91, no. 11 (2019): 10–15. http://dx.doi.org/10.26442/00403660.2019.11.000359.

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Aim. Diabetes mellitus (DM) is known to be a risk factor in adverse outcomes and complications in many infectious diseases. In the combination of hemorrhagic fever with renal syndrome (HFRS) and DM there are mutually exclusive pathogenetic States - hyperosmolarity, characteristic of DM is layered on the reduction of osmotic blood pressure in HFRS. Under these conditions, the effect of one disease (DM) on the clinical manifestations of another (HFRS) is not obvious. The aim of the work is to find out the clinical features during hfps in patients with DM. Materials and methods. The study is base

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Sehgal, Ayushi, Sanya Mehta, Kritika Sahay, et al. "Hemorrhagic Fever with Renal Syndrome in Asia: History, Pathogenesis, Diagnosis, Treatment, and Prevention." Viruses 15, no. 2 (2023): 561. http://dx.doi.org/10.3390/v15020561.

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Hemorrhagic Fever with Renal Syndrome (HFRS) is the most frequently diagnosed zoonosis in Asia. This zoonotic infection is the result of exposure to the virus-contaminated aerosols. Orthohantavirus infection may cause Hemorrhagic Fever with Renal Syndrome (HRFS), a disease that is characterized by acute kidney injury and increased vascular permeability. Several species of orthohantaviruses were identified as causing infection, where Hantaan, Puumala, and Seoul viruses are most common. Orthohantaviruses are endemic to several Asian countries, such as China, South Korea, and Japan. Along with th

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Manakhov, K. M., E. V. Povysheva, A. R. Gilyazova, and D. S. Sarksyan. "Features of the course of hemorrhagic fever with renal syndrome in HIV-infected patients." Russian Journal of Infection and Immunity 11, no. 5 (2020): 951–57. http://dx.doi.org/10.15789/2220-7619-fot-1395.

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Human immunodeficiency virus (HIV) is a significant medical and social problem for many developed countries. HIV infection is featured with developing chronic kidney pathology as well as acute renal damage. In some regions, hemorrhagic fever with renal syndrome (HFRS) can contribute somehow to developing renal pathology in HIVinfected subjects. The aim of the study was to identify clinical and laboratory features of HFRS course during HIV infection. A retrospective study was conducted by forming two groups: group 1 consisted of 9 patients suffered from HFRS together with verified HIV infection

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Corinaldesi, Giorgio, and Christian Corinaldesi. "Hemorrhagic Fever in Schoenlein Henoch Purpura." Blood 110, no. 11 (2007): 3941. http://dx.doi.org/10.1182/blood.v110.11.3941.3941.

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Abstract Schoenlein Henoch Purpura (SHP) may show a cohort of symptoms such as: a palpable purpuric rash where lesions may be prominent mostly on lower extremities, abdominal pain, arthritis and nephritis. It is an inflammatory disorder characterized by an IgA-mediated vasculitis with immune complexes deposition in smaller veins, capillaries and arterioles which often occur as a response to infections (mycoplasma, streptococcus group A, Campylobacter enteritis, Helycobacter, Herpes virus, Parvovirus B19, Epstein-Barr virus), or to an exposure to allergens, drugs, some particular food, cold, or

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Mukhetdinova, G. A., G. D. Boris, R. M. Fazlyeva, G. Kh Mirsaeva, E. R. Kamaeva, and A. A. Talkhina. "Cardiovascular risk and chronic kidney disease in convalescents of hemorrhagic fever with renal syndrome." Practical medicine 17, no. 2 (2019): 94–98. http://dx.doi.org/10.32000/2072-1757-2019-2-94-98.

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Manakhov, K. M., D. S. Sarksyan, M. V. Dudarev, T. O. Tolstoluckaya, N. S. Ponomarenko, and V. V. Maleev. "Molecular genetic characteristics of hemostasis in hemorrhagic fever with renal syndrome." Kazan medical journal 101, no. 6 (2020): 812–19. http://dx.doi.org/10.17816/kmj2020-812.

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Aim. To assess the predictive value of single-nucleotide polymorphisms of hemostasis and folate cycle genes in hemorrhagic fever with renal syndrome (HFRS). Methods. 43 patients undergoing HFRS were examined based on the Republican clinical infectious diseases hospital in Izhevsk. Toxic shock syndrome (TSS) in the decompensated phase, pulmonary edema in the alveolar phase, and acute kidney injury (AKI) at stage F [RIFLE criteria (risk, injury, failure, loss, end-stage renal disease)] were registered as complications. Molecular analysis of patients genomic DNA was performed after its isol

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Hansson, Magnus, Rasmus Gustafsson, Chloé Jacquet та ін. "Cystatin C and α-1-Microglobulin Predict Severe Acute Kidney Injury in Patients with Hemorrhagic Fever with Renal Syndrome". Pathogens 9, № 8 (2020): 666. http://dx.doi.org/10.3390/pathogens9080666.

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Puumala orthohantavirus causes hemorrhagic fever with renal syndrome (HFRS) characterized by acute kidney injury (AKI), an abrupt decrease in renal function. Creatinine is routinely used to detect and quantify AKI; however, early AKI may not be reflected in increased creatinine levels. Therefore, kidney injury markers that can predict AKI are needed. The potential of the kidney injury markers urea, cystatin C, α1-microglobulin (A1M) and neutrophil gelatinase-associated lipocalin (NGAL) to detect early AKI during HFRS was studied by quantifying the levels of these markers in consecutively obtai

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Koskela, Sirpa, Satu Mäkelä, Tomas Strandin, et al. "Coagulopathy in Acute Puumala Hantavirus Infection." Viruses 13, no. 8 (2021): 1553. http://dx.doi.org/10.3390/v13081553.

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Puumala hantavirus (PUUV) causes a hemorrhagic fever with renal syndrome (HFRS), also called nephropathia epidemica (NE), which is mainly endemic in Europe and Russia. The clinical features include a low platelet count, altered coagulation, endothelial activation, and acute kidney injury (AKI). Multiple connections between coagulation pathways and inflammatory mediators, as well as complement and kallikrein–kinin systems, have been reported. The bleeding symptoms are usually mild. PUUV-infected patients also have an increased risk for disseminated intravascular coagulation (DIC) and thrombosis

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Kim, Yon Su, Jung Sang Lee, Curie Ahn, et al. "Magnetic Resonance Imaging of the Kidney in Hemorrhagic Fever with Renal Syndrome: Its Histopathologic Correlation." Nephron 76, no. 4 (1997): 477–80. http://dx.doi.org/10.1159/000190240.

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Kan, Elena A., Vladimir V. Salukhov, Yury V. Rudakov, Alexander N. Kovalenko, and Oleg Y. Golubtsov. "Features of clinical and laboratory diagnostics of hantavirus infection at a prehospital stage." Bulletin of the Russian Military Medical Academy 23, no. 4 (2021): 19–24. http://dx.doi.org/10.17816/brmma63707.

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The features of clinical and laboratory diagnostics of hantavirus infection at the prehospital stage in the regions of the Northwestern Federal District is considered. The analysis of the terms of patients treatment from the moment of the appearance of the first symptoms of the disease was carried out. It was found that more than half of the patients sought a medical help during the height of the disease. The structure of hospitalizations of the patients with a hemorrhagic fever with renal syndrome who were admitted to inpatient treatment was studied; most patients were hospitalized by the amb

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Cvetko Krajinović, Lidija, Kristian Bodulić, Renata Laškaj, et al. "Hemorrhagic Fever with Renal Syndrome Patients Exhibit Increased Levels of Lipocalin-2, Endothelin-1 and NT-proBNP." Life 13, no. 11 (2023): 2189. http://dx.doi.org/10.3390/life13112189.

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Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease caused by viruses of the Orthohantavirus genus. This syndrome is characterized by renal and cardiopulmonary implications detectable with different biomarkers. Here, we explored the role of serum and urine levels of lipocalin-2, endothelin-1 and N-terminal pro-brain natriuretic peptide (NT-proBNP) in HFRS pathology. A total of twenty-eight patients hospitalized due to a Puumala orthohantavirus infection were included, with serum and urine samples collected on patient admission (acute phase) and discharge (convalescent pha

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Rista, Elvana, Arben Pilaca, Ilir Akshija, et al. "Hemorrhagic fever with renal syndrome in Albania. Focus on predictors of acute kidney injury in HFRS." Journal of Clinical Virology 91 (June 2017): 25–30. http://dx.doi.org/10.1016/j.jcv.2017.03.021.

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Malkin, G. A., T. K. Dzagurova, N. A. Korotina, et al. "Features of the replication of hantaviruses - pathogens of hemorrhagic fever with renal syndrome in cell cultures of different origin." Epidemiology and Infectious Diseases 19, no. 4 (2014): 18–24. http://dx.doi.org/10.17816/eid40808.

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There are presented results of the adaptation ofpathogens of hemorrhagic fever with renal syndrome (HFRS) virus Puumala and Dobrava strains, to the reproduction in cell cultures of the simian origin - Green monkey kidney (Vero, 4647), Green monkey spleen (455), calf kidney (PT-1) and sheep kidney (4184). Hantaviruses were shown to be able to adapt to the replication in the new cellular system differing in species origin from the culture of Vero E6 origin in which the strains were isolated. This fact demonstrates the heterogeneity of hantavirus population, with the existence of «quasispecies» w

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Humayoun Kabir, Muhammad, Abdullah Al Faruk, Sheikh Hasibur Rahman, Md Nazmul Haque Sarker, Sarder Raihan Sadique, and Kartick Chanda Shaha. "Respiratory Manifestation of Dengue Fever in a Tertiary Care Hospital in Bangladesh." International Journal of Advanced Multidisciplinary Research and Studies 5, no. 1 (2025): 881–84. https://doi.org/10.62225/2583049x.2025.5.1.3737.

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Objective To investigate the respiratory signs observed in individuals hospitalized due to dengue infection. Methods This observational study encompassed a cohort of 50 individuals diagnosed with dengue fever, as confirmed by the presence of NS1 antigen, who were hospitalized to Shaheed Captain Mansur Ali Medical College Hospital in Uttara, Dhaka, Bangladesh. Participants were enrolled from the Intensive Care Unit (ICU) and respiratory medicine ward over the period of June 2022 to October 2022. The screening process involved doing a physical examination and obtaining a comprehensive clinical h

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Lebecque, Olivier, and Michaël Dupont. "Puumala hantavirus: an imaging review." Acta Radiologica 61, no. 8 (2019): 1072–79. http://dx.doi.org/10.1177/0284185119889564.

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Puumala virus (PUUV) is the most common hantavirus in Europe. It is known to cause nephropathia epidemica, which is considered a mild type of hemorrhagic fever with renal syndrome. However, it does not only involve the kidneys and is rarely accompanied by symptomatic hemorrhage. We review the imaging abnormalities caused by PUUV infection, from head to pelvis, emphasizing the broad spectrum of possible findings and bringing further support to a previously suggested denomination “Hantavirus disease” that would encompass all clinical manifestations. Although non-specific, knowledge of radiologic

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Khoroshun, E. M., K. I. Bodnia, L. V. Zavgorodnia, et al. "Cases of hemorrhagic fever with renal syndrome caused by hantavirus in the Kharkiv region among military personnel." EMERGENCY MEDICINE 21, no. 3 (2025): 258–62. https://doi.org/10.22141/2224-0586.21.3.2025.1867.

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The military personnel’s stay in the field, in places of natural hantavirus foci in the Kharkiv region, and contact with rodents led to the development of hemorrhagic fever with renal syndrome. Serologic testing for IgM and IgG to hantaviruses revealed the Puumala serotype in all 11 patients. The main complaints were fever, general weakness, headache, low back pain, muscle pain, decreased urine output and quantity. An objective examination revealed an enlarged liver and a positive Pasternacki’s symptom. All participants had erythrocytosis and thrombocytopenia. Patients also had increased level

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Yadav, Dr Srikant, Dr Dnyanesh N Morkar, Dr Akashdeep Singh, and Dr Hima morkar. "Acute Kidney Injury In Dengue Fever, One Year Hospital Based Cross Sectional Study." Journal of Infectious Diseases 10, no. 1 (2025): 1–14. https://doi.org/10.52338/joid.2025.4625.

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Arboviruses pose a significant public health challenge, particularly in tropical and subtropical regions, where they contribute to frequent epidemics with substantial economic and social impacts. Among them, the dengue virus (DENV), transmitted by Aedes mosquitoes, is the most prevalent arthropod-borne viral infection in humans. Dengue fever (DF) has a vast global footprint, with an estimated 2.5 billion people at risk, and outbreaks reported in over 100 countries, primarily in Southeast Asia, the Pacific, and the Americas. While traditionally considered an urban disease, dengue is increasingl

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Ramindla, Sruthi, Saif Quaiser, Anjum Parvez, Shan Ullah Khan, and Ruhi Khan. "Rare presentations of a common infection." Annals of Medical Science & Research 4, no. 1 (2025): 27–34. https://doi.org/10.4103/amsr.amsr_28_24.

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Abstract Dengue infection can present as dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS). The World Health Organization (WHO) has coined the term "expanded dengue syndrome" (EDS) for cases that do not fit into either DHF or DSS. These cases showcase unusual symptoms in various organs such as the cardiovascular system, nervous system, kidneys, gut, and hematological system, and are increasingly being reported as EDS. EDS is globally on the rise with unusual characteristics and greater severity. There are escalating reports of rare manifestations involving seve

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Islamov, T.Sh, Ismoil Аxmedjanovich Аxmedjanov, Nargiza Ismailovna Аxmedjanova, and M.F. Xamidova. "CLINICAL AND LABORATORY CHARACTERISTICS OF VARIOUS FORMS OF ACUTE GLOMERULONEPHRITIS IN CHILDREN." Journal of reproductive health and uro-nephrology research 3, no. 2 (2022): 6. https://doi.org/10.5281/zenodo.6677878.

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 In the structure of renal pathology in childhood, a special place is occupied by glomerulonephritis. The aim of this work was to study the clinical features and evaluate laboratory parameters in children with primary and secondary acute GN. Material and research methods. Only 70 sick children were under observation. Of these, 25 had capillary toxic nephritis (CN), 20 had primary glomerulonephritis (PGN) with a leading hematuric syndrome, and 25 had hemorrhagic vasculitis (HV b/pp) without subsequent kidney damage. Results. When comparing patients with capillary toxic nephritis and hemorr

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Dzagurova, T. K., A. A. Ishmukhametov, V. A. Bakhtina, et al. "HEMORRHAGIC FEVER WITH RENAL SYNDROME GROUP OUTBREAK CAUSED BY SOCHI VIRUS." Problems of Virology, Russian journal 64, no. 1 (2019): 36–41. http://dx.doi.org/10.18821/0507-4088-2019-64-1-36-41.

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Introduction. Hemorrhagic fever with renal syndrome (HFRS) occupies a leading place among natural focal human diseases in the Russian Federation. Sporadic incidence of HFRS-Sochi has been annually recorded in the Krasnodar Territory since 2000. The group outbreak of the HFRS-Sochi was first registered in Gelendzhik in the fall of 2013. Material and methods. Serological methods were used: indirect immunofluorescence, enzyme immunoassay, FRNT in Vero cells, and methods for the viral RNA detection: PCR and RT-PCR. Results. Data of clinical, epidemiological, immunological and molecular studies of

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Mačak Šafranko, Željka, Lana Jakopec, Karla Svaguša, et al. "Serum Concentrations of TIM-3, LAG-3, and PD-1 in Patients with Hemorrhagic Fever with Renal Syndrome." Life 14, no. 5 (2024): 551. http://dx.doi.org/10.3390/life14050551.

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Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease widespread in Europe and Asia. HFRS is caused by negative-sensed single-stranded RNA orthohantaviruses transmitted to humans through inhaling aerosolized excreta of infected rodents. Symptoms of HFRS include acute kidney injury, thrombocytopenia, hemorrhages, and hypotension. The immune response raised against viral antigens plays an important role in the pathogenesis of HFRS. Inhibitory co-receptors are essential in regulating immune responses, mitigating immunopathogenesis, and reducing tissue damage. Our research showed

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Krivoruchko, I. V., S. A. Pshenichnaya, and S. P. Kokoreva. "Epidemiological and clinical aspects of HFRS in the territory of the Voronezh region." Sanitarnyj vrač (Sanitary Doctor), no. 4 (April 19, 2024): 246–54. http://dx.doi.org/10.33920/med-08-2404-01.

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At this time, hemorrhagic fever with renal syndrome remains one of the most common infectious diseases in the Russian Federation. An active natural focus of HFRS is the Voronezh region, where the natural reservoir of hantaviruses and the source of infection for people are wild rodents — bank vole, field mouse, and gray vole. The highest incidence rates of HFRS in the Voronezh region were recorded in 2019, significantly exceeding the rates of other years. The article presents data on the features of the epidemiology of HFRS and analyzes in detail the characteristic clinical manifestations of th

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Shakirova, Venera, Maria Markelova, Yuriy Davidyuk, et al. "Rosuvastatin as a Supplemental Treatment for the Clinical Symptoms of Nephropathia Epidemica: A Pilot Clinical Study." Viruses 16, no. 2 (2024): 306. http://dx.doi.org/10.3390/v16020306.

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Nephropathis epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS), is an acute zoonotic disease endemic in the Republic of Tatarstan. This study aimed to assess the impact of rosuvastatin on the clinical and laboratory results of NE. A total of 61 NE patients and 30 controls were included in this study; 22 NE patients and 7 controls received a daily dose of rosuvastatin (10 mg) for ten consecutive days. Serum samples were collected on days 1, 5, and 10 after admission to the hospital. These samples were analyzed to determine the levels of lipids, cytokines, and kidney to

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Mitra, Manu. "Complexity of Hantavirus, its Traits and Treatment." American Journal of Biomedical Science & Research 2, no. 6 (2019): 265–68. https://doi.org/10.34297/AJBSR.2019.02.000620.

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Hantavirus is also called as orthohantavirus and are singlestranded, enveloped, negative RNA virus [(-) ss RNA viruses]. It was named after Hantan River area in South Korea where its occurrence was observed and was isolated in 1976 by Karl M. Johnson and Ho-Wang Lee. There are many strains of Hantavirus; normally rodents are the carrier of these virus. Various strains carried by different rodent species are familiar to cause various types of illness in human, most remarkably, Hemorrhagic Fever with Renal Syndrome (HFRS) which was identified during the Korean War – and Hantavirus Pulmonar

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Outinen, Tuula K., Satu Mäkelä, Jan Clement, Antti Paakkala, Ilkka Pörsti, and Jukka Mustonen. "Community Acquired Severe Acute Kidney Injury Caused by Hantavirus-Induced Hemorrhagic Fever with Renal Syndrome Has a Favorable Outcome." Nephron 130, no. 3 (2015): 182–90. http://dx.doi.org/10.1159/000433563.

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Duangmala, Tanaporn, Pagakrong Lumbiganon, and Pope Kosalaraksa. "Unusual clinical manifestations of dengue infection in children in a tertiary care hospital in northeast Thailand." Asian Biomedicine 8, no. 1 (2014): 97–103. http://dx.doi.org/10.5372/1905-7415.0801.267.

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AbstractBackground: Dengue virus infection has been a public health concern in Thailand. In the past decades, there has been recent interest concerning unusual clinical manifestations in both dengue fever (DF) and dengue hemorrhagic fever (DHF).Objective: We described the unusual clinical manifestations and outcomes of children with dengue admitted to a tertiary care hospital in northeast Thailand.Materials and Methods: A study was conducted on the 73 patients with serologically confirmed dengue infection admitted to Srinagarind Hospital, a tertiary care facility in northeast Thailand between

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Soegijanto, Soegeng. "UPDATE MANAGEMENT OF DENGUE COMPLICATION IN PEDIATRIC." Indonesian Journal of Tropical and Infectious Disease 2, no. 1 (2015): 1. http://dx.doi.org/10.20473/ijtid.v2i1.91.

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Dengue virus infection is one of the important health problems in Indonesia, although the mortality rate has been decreased but many dengue shock syndrome cases is very difficult to be solving handled. It might be due to nature course of dengue virus infection is very difficult to predict of the earlier time of severity occur. THE AIM To get idea to make update management of dengue complication in pediatric. MATERIAL AND METHOD Data were compiled from Dr. Soetomo Hospital Surabaya in 2009. The diagnosis of all cases was based on criteria WHO 1997 and PCR examination in Institute Tropical Disea

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Tietäväinen, Johanna, Satu Mäkelä, Heini Huhtala, et al. "The Clinical Presentation of Puumala Hantavirus Induced Hemorrhagic Fever with Renal Syndrome Is Related to Plasma Glucose Concentration." Viruses 13, no. 6 (2021): 1177. http://dx.doi.org/10.3390/v13061177.

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Puumala hantavirus (PUUV) causes a hemorrhagic fever with renal syndrome characterized by thrombocytopenia, increased capillary leakage, and acute kidney injury (AKI). As glucosuria at hospital admission predicts the severity of PUUV infection, we explored how plasma glucose concentration associates with disease severity. Plasma glucose values were measured during hospital care in 185 patients with PUUV infection. They were divided into two groups according to maximum plasma glucose concentration: P-Gluc < 7.8 mmol/L (n = 134) and P-Gluc ≥ 7.8 mmol/L (n = 51). The determinants of disease se

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Nusshag, Christian, Josephine Uhrig, Gefion Gruber, Pamela Schreiber, Martin Zeier, and Ellen Krautkrämer. "Glomerular Injury Is Associated with Severe Courses of Orthohantavirus Infection." Pathogens 13, no. 8 (2024): 693. http://dx.doi.org/10.3390/pathogens13080693.

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Hemorrhagic fever with renal syndrome (HFRS) induced by Eurasian pathogenic orthohantaviruses is characterized by acute kidney injury (AKI) with often massive proteinuria. The mechanisms of the organ-specific manifestation are not completely understood. To analyze the role of glomerular and tubular damage in kidney injury induced by HFRS, we measured specific markers in urine samples of patients with acute Puumala virus (PUUV) infection and determined their correlation with disease severity. Levels of α1-microglobulin (α1-MG) and kidney injury molecule 1 (KIM-1), which is expressed by injured

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Krautkrämer, Ellen, and Martin Zeier. "Hantavirus Causing Hemorrhagic Fever with Renal Syndrome Enters from the Apical Surface and Requires Decay-Accelerating Factor (DAF/CD55)." Journal of Virology 82, no. 9 (2008): 4257–64. http://dx.doi.org/10.1128/jvi.02210-07.

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ABSTRACT The Old World hantaviruses, members of the family Bunyaviridae, cause hemorrhagic fever with renal syndrome (HFRS). Transmission to humans occurs via inhalation of aerosols contaminated with the excreta of infected rodents. The viral antigen is detectable in dendritic cells, macrophages, lymphocytes, and, most importantly, microvascular endothelial cells. However, the site and detailed mechanism of entry of HFRS-causing hantaviruses in polarized epithelial cells have not yet been defined. Therefore, this study focused on the entry of the pathogenic hantaviruses Hantaan and Puumala int

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Latypova, G. R., R. T. Murzabaeva, D. A. Valishin, A. Zh Gilmanov, and A. Kh Lukmanova. "Use of the drug angiovit in hemorrhagic fever with renal syndrome: evaluation of markers of vascular endothelial damage and kidney disfunction." Infectious diseases: News, Opinions, Training 11, no. 4 (2022): 99–105. http://dx.doi.org/10.33029/2305-3496-2022-11-4-99-105.

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