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Dissertations / Theses on the topic 'Hemostasis'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Keebaugh, Audrey Elizabeth. "Evaluation of hemostasis in hyperthyroid cats." Thesis, Virginia Tech, 2020. http://hdl.handle.net/10919/99376.

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Background: Hyperthyroid cats are predisposed to thrombus formation. The mechanism for thrombogenesis is currently unknown, but could be associated with altered hemostasis as seen in hyperthyroid humans. Objective: The purpose of this study was to evaluate markers of hemostasis in hyperthyroid cats compared to healthy cats, and in hyperthyroid cats before and after treatments with radioactive iodine (RIT). Methods: Twenty-five cats with hyperthyroidism and 13 healthy euthyroid cats > 8 years of age were studied. Prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen,

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2

Hormiga, Hernando Gonzalez [UNESP]. "Aplicação de diferentes pinças hemostáticas em veias de equinos: estudo morfológico." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/144581.

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3

Gonçalves, Daniele Silvano. "Avaliação das alterações hemorrágicas e tromboembólicas em cães com doença renal crônica." Botucatu, 2016. http://hdl.handle.net/11449/134372.

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Orientador: Regina Kiomi Takahira<br>Resumo: A doença renal crônica (DRC) acomete principalmente cães idosos e tem como característica principal a perda irreversível da função renal. A DRC em cães promove alterações metabólicas graves, caracterizadas frequentemente pela azotemia, hipoalbuminemia e anemia não regenerativa. Tanto a azotemia quanto a uremia predispõem a alterações hemostáticas que podem levar a quadros hemorrágicos. Além das disfunções plaquetárias, deficiência de anticoagulantes naturais e redução da fibrinólise são fatores que predispõem ao tromboembolismo. Este trabalho tem co

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4

Joesph, Wiencek R. "Regulating Hemostasis: The Factor Va Cofactor Effect." Cleveland State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=csu1431514489.

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5

Lindfelt, Jan O. W. "Hepatic nerves in hemostasis and glucose metabolism :." Lund : Dept. of Surgery, Lund University, 1993. http://catalog.hathitrust.org/api/volumes/oclc/39654187.html.

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6

Peterle, Daniele. "Molecular Mechanism in the Alteration of Hemostasis." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3426350.

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Hemostasis is a finely tuned physiological process that, through the concerted action of several blood cells and proteins, maintains the integrity of the vascular system. This stepwise process begins after a vessel wall injury and includes: an initial vasospasm, a platelet plug formation (primary hemostasis), an assembly and activation of the coagulation factors that results in fibrin deposition at the site of injury (secondary hemostasis), and a final dissolution of the fibrin clot that restores the blood vessel patency (fibrinolysis) (Chapter 1). Alterations affecting one or more of these de

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7

Teixeira, Bruno Costa. "Efeito de diferentes intensidades de exercício aeróbio prévio, sobre a curva lipêmica, inflamação e hemostasia de sujeitos submetidos à refeição hiperlipídica." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/142537.

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Introdução: O consumo habitual de refeições ricas em gordura tem se mostrado indutor de doenças cardiovasculares (DCV), afetando o equilíbrio entre os sistemas de coagulação e fibrinólise e também induzindo o aumento de marcadores inflamatórios. Por outro lado, o exercício físico tem sido indicado como intervenção por atenuar o incremento da inflamação e equilibrar os sistemas hemostáticos em indivíduos que consomem uma refeição hiperlipídica (RH). Objetivo: Verificar o efeito subagudo de duas sessões com intensidades diferentes de exercício aeróbio na curva lipêmica, inflamação, hemostasia em

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8

Boknäs, Niklas. "Studies on interfaces between primary and secondary hemostasis." Doctoral thesis, Linköpings universitet, Avdelningen för mikrobiologi och molekylär medicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132413.

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Our conceptual understanding of hemostasis is still heavily influenced by outdated experimental models wherein the hemostatic activity of platelets and coagulation factors are understood and studied in isolation. Although perhaps convenient for researchers and clinicians, this reductionist view is negated by an ever increasing body of evidence pointing towards an intimate relationship between the two phases of hemostasis, marked by strong interdependence. In this thesis, I have focused on factual and proposed interfaces between primary and secondary hemostasis, and on how these interfaces can

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9

Kurdi, Mohamad. "Study of the clearance of proteins of hemostasis." Paris 7, 2011. http://www.theses.fr/2012PA077071.

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Le but de ce projet de thèse a été d'étudier la clairance de glycoprotéines jouant un rôle clé dans l'hémostase, le facteur X (FX) et le couple facteur Willebrand (FW)/facteur VIII (FVIII) qui circule dans le plasma sous forme de complexe non covalent. Dans la première partie de nos travaux, nous avons étudié l'implication des N-glycosylations du FX sur sa clairance. Il avait été préalablement établi par l'équipe que ces N-glycans influençaient la cinétique d'élimination du FX. Nous avons désormais établi qu'ils influencent également la biodistribution et les interactions cellulaires de la pro

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10

Shoffstall, Andrew J. "The Use of Synthetic Platelets to Augment Hemostasis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1363775111.

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11

Joshi, Smita. "CONTROLLING PLATELET SECRETION TO MODULATE HEMOSTASIS AND THROMBOSIS." UKnowledge, 2018. https://uknowledge.uky.edu/biochem_etds/37.

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Upon vascular injury, activated blood platelets fuse their granules to the plasma membrane and release cargo to regulate the vascular microenvironment, a dynamic process central to platelet function in many critical processes including hemostasis, thrombosis, immunity, wound healing, angiogenesis etc. This granule- plasma membrane fusion is mediated by a family of membrane proteins- Soluble N-ethyl maleimide Attachment Receptor Proteins(SNAREs). SNAREs that reside on vesicle (v-SNAREs) /Vesicle-Associated Membrane Proteins(VAMPs) interact with target/t-SNAREs forming a trans-bilayer complex th

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12

Assunção, Pedrita Carvalho Ferreira. "Tromboelastometria (ROTEM) em gatos da raça Maine Coon portadores e não portadores da mutação (A31P) no gene MYBPC3 para miocardiopatia hipertrófica." Botucatu, 2019. http://hdl.handle.net/11449/180649.

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Orientador: Regina Kiomi Takahira<br>Resumo: A miocardiopatia hipertrófica é a doença cardíaca mais observada em gatos da raça Maine Coon e está diretamente relacionada à presença de uma mutação (A31P) que ocorre no gene da proteína C miosina ligante (MYBPC3). A doença pode provocar em determinados pacientes quadros secundários graves como o tromboembolismo arterial (TEA). O objetivo do presente trabalho foi avaliar gatos da raça Maine Coon não portadores da mutação A31P no gene MYBPC3 (G1) e portadores da mutação A31P no gene MYBPC3 (G2), por meio do perfil tromboelastométrico. Foram selecion

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13

Hormiga, Hernando Gonzalez. "Aplicação de diferentes pinças hemostáticas em veias de equinos estudo morfológico /." Botucatu, 2016. http://hdl.handle.net/11449/144581.

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Orientador: Carlos Alberto Hussni<br>Banca: Marcos Jun Watanabe<br>Banca: Cláudia Helena Pellizzon<br>Resumo: Foi realizada a avaliação morfológica e morfométrica da veia cefálica submetida à pinçamento de cinco equinos hígidos. Foram testadas as pinças hemostáticas: Diffenbach bulldog, De Bakey bulldog, Rochester reta e De Bakey com cremalheira. Após 15 minutos da aplicação das referidas pinças, foi realizada a flebectomia parcial e coletadas as amostras referentes a cada segmento do vaso pinçado e do segmento controle sem pinçamento. Das peças procedeu-se as preparações histológicas dos segm

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14

Hwang, Joo Ha. "Ultrasound-mediated vascular bioeffects : applications for hemostasis and sclerotherapy /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/7992.

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15

Eriksson-Berg, Margita. "Hemostasis in middle-aged women with coronary heart disease /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-978-1/.

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16

Maji, Debnath. "A Microfluidic Dielectric Sensor for Comprehensive Assessment of Hemostasis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1579798937224898.

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17

PAVANI, Giulia. "The Endothelial Protein C Receptor enhances FVIIa mediated hemostasis." Doctoral thesis, Università degli studi di Ferrara, 2014. http://hdl.handle.net/11392/2388933.

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Recombinant activated human Factor VII (rFVIIa) is an established hemostatic agent in hemophilia but its mechanism of action remains unclear. Although tissue factor (TF) is its natural receptor, rFVIIa also interacts with the endothelial protein C receptor (EPCR) through its g-carboxyglutamic acid (Gla) domain with unknown hemostatic consequences in vivo. Here, we study whether EPCR facilitates rFVIIa hemostasis in hemophilia using a mouse model system. Murine activated FVII (mFVIIa) is functionally homologous to rFVIIa, but binds poorly to murine EPCR (mEPCR). We modified mFVIIa to gain

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18

Сабадаш, В. Є., Є. Є. Сабадаш, Т. В. Сисойкіна та ін. "Стан тромбоцитарного гемостазу у хворих на хозл з хронічним легеневим серцем в динаміці лікування антиагрегантам". Thesis, Видавництво СумДУ, 2009. http://essuir.sumdu.edu.ua/handle/123456789/11106.

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19

Hoore, Masoud [Verfasser], Gerhard [Gutachter] Gompper, and Krug [Gutachter] Joachim. "Modeling Primary Hemostasis / Masoud Hoore ; Gutachter: Gerhard Gompper, Krug Joachim." Köln : Universitäts- und Stadtbibliothek Köln, 2018. http://d-nb.info/1161223282/34.

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20

Batista, Saulo Hilton Botelho. "Evaluation of the use of different local hemostatics procedures to manage post extraction bleeding in patients under anticoagulation treatment." Universidade Federal do CearÃ, 2010. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=6328.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>The therapeutic use of Varfarin, the most common oral anticoagulant it is indicated in many cases, including the atrial fibrillation, cardiac valvular prostheses and venous trombolic disease. Many discussions still exist related to the suspension or not before tooth extraction. People who are for itâs suspension agree that it may increase the risk of hemorrhage, however the ones who prefer to maintain itâs use refer the high risk of tromboembolism. Due to the controversy related to the cronic use of oral anticoagulant before tooth

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21

Espinosa, Sánchez Sebastián Antonio. "Evaluación de medidas hemostáticas locales postexodoncia bajo terapia anticoagulante oral mantenida en pacientes con INR bajo 4.0." Tesis, Universidad de Chile, 2004. http://www.repositorio.uchile.cl/handle/2250/110709.

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El manejo quirúrgico de pacientes bajo tratamiento anticoagulante oral ha estado por mucho tiempo determinado por la suspensión del fármaco 2 días antes del acto quirúrgico. La intención de este trabajo fue la de dejar en el pasado dicha metodología, manteniendo la terapia anticoagulante, realizando un examen de laboratorio previo para obtener el nivel de anticoagulación en que se encuentra el paciente y una vez realizada la exodoncia (no complicada), otorgar hemostasia con medios locales mecánicos. Según los resultados obtenidos, aparentemente sería un procedimiento seguro, tomando en cuenta

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22

Labuda, Cecille Pemberton. "Enhanced high intensity focused ultrasound heat deposition for more efficient hemostasis /." Full text available from ProQuest UM Digital Dissertations, 2008. http://0-proquest.umi.com.umiss.lib.olemiss.edu/pqdweb?index=0&did=1905744431&SrchMode=1&sid=8&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1279568381&clientId=22256.

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Thesis (Ph.D.)--University of Mississippi, 2008.<br>Typescript. Vita. "May 2008." Major professor: Charles C. Church Includes bibliographical references (leaves 95-102). Also available online via ProQuest to authorized users.

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23

Druga, David A. "Feasibility of combat hemostasis methods in civilian prehospital emergency medical care." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12353.

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Thesis (M.A.)--Boston University<br>Uncontrolled hemorrhage is the leading cause of preventable traumatic death in both military and civilian populations. Hemorrhage often causes coagulopathy, which intensifies hemorrhage and complicates its treatment. The armed conflicts in Afghanistan and Iraq have allowed the military to test new hemostatic products and procedures in an effort to better control hemorrhage and reduce its associated morbidity and mortality rates. These methods were analyzed for efficacy and suitability in the civilian prehospital setting. Several invasive and non-invasive int

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24

Riescher-Tuczkiewicz, Alix. "Study of complex hemostasis in patients with cirrhosis : pathophysiology and management." Electronic Thesis or Diss., Université Paris Cité, 2024. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=7690&f=75939.

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La cirrhose est une maladie chronique du foie associée à des perturbations complexes de l'hémostase. Les patients atteints de cirrhose peuvent présenter des saignements, notamment après des gestes invasifs, qui sont associés à une morbi-mortalité élevée. Une meilleure compréhension de l'hémostase complexe des patients atteints de cirrhose et une meilleure prédiction des saignements post-procéduraux sont donc nécessaires pour améliorer la prise en charge de ces patients. L'objectif de mon travail était : (a) d'étudier deux acteurs de l'hémostase, la protéase nexine 1 (PN-1) et les vésicules ext

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Volpato, Julieta. "Efeitos da contenção física e química sobre as variáveis hematológicas e hemostáticas em gatos." Universidade do Estado de Santa Catarina, 2013. http://tede.udesc.br/handle/handle/896.

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Made available in DSpace on 2016-12-08T16:24:16Z (GMT). No. of bitstreams: 1 PGCA13MA119.pdf: 243424 bytes, checksum: 0b630548fe7f6b8f2081e1a779e8edd2 (MD5) Previous issue date: 2013-02-27<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The blood sampling should not be influenced by factors that interfere in the results, but this is not always possible, especially in cats. The use of sedation protocols can assist in obtaining samples, but it is not known whether there are changes in haematological values and hemostasis. The aim of this study was to evaluate the parameters o

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Dalmolin, Magnus Larruscaim. "Avaliação da hemostasia em cães: fator de Von Willebrand e tempo de protrombina e tromboplastina parcial ativada." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/115192.

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A doença de von Willebrand (DvW) é um defeito qualitativo/quantitativo do fator de von Willebrand (FvW), uma glicoproteína que desempenha um papel essencial na adesão e agregação plaquetária. Cães acometidos por esta diátese hemorrágica hereditária podem ser assintomáticos, ou apresentar sinais clínicos de um problema hemostático primário, especialmente hemorragias em superfícies mucosas. O diagnóstico da DvW baseia-se na quantificação do FvW plasmático, este sendo atualmente realizado por ELISA – antígeno FvW (Ag:FvW). O presente trabalho desenvolveu um ensaio para quantificação do Ag:FvW em

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Oliveira, Jéssica Rodrigues de. "Perfis hemostático e hematológico de cadelas acometidas por carcinoma mamário /." Jaboticabal, 2016. http://hdl.handle.net/11449/141990.

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Orientador: Márcia Ferreira da Rosa Sobreira<br>Coorientador: Annelise Carla Camplesi<br>Banca: Fábio Nelson Gava<br>Banca: Sabryna Gouveia Calazans<br>Resumo: Tumores mamários são frequentes em cadelas e apresenta comportamento biológico semelhante aos que ocorrem nas mulheres, tornando a cadela um excelente modelo de estudo comparativo. Os distúrbios hemostáticos são achados comuns em pacientes humanos com câncer, e os mecanismos que conduzem a ativação da coagulação no câncer envolvem o fator tissular, o fator procoagulante do câncer e as citocinas inflamatórias. E já está bem estabelecido

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28

Albert, Johanna. "Effects of nitric oxide on hemostasis with special attention to platelet function /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3783-4/.

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29

Sundström, Johanna. "Nanoparticle size-dependent activation of the hemostasis and the innate immune system." Thesis, Uppsala universitet, Institutionen för immunologi, genetik och patologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-298888.

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Nanoparticles are small particles with a size range of 10-1000 nm. They exist all around us, in make-up, dust and even food. They can enter our bloodstream through different pathways such as inhalation and cause thrombosis and multiple organ failure. They can be modified to act as drug deliverers and can treat even hard to reach places because of their small size. Studies have shown that the activation of the coagulation system and complement system is dependent on the size of the nanoparticle. This study’s main focus was to determine if there was a difference in the degree of activation on he

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Souza, Evandro de Oliveira. "Avaliação funcional das plaquetas em pacientes com cirrose e sua relação com o risco de sangramento após ligadura elástica de varizes esofagianas." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5168/tde-16112017-081301/.

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Introdução: O sangramento por queda de escara é uma complicação potencialmente letal da ligadura elástica (LE) de varizes de esôfago. Os fatores relacionados a esse evento são pouco explorados na literatura, porém a coagulopatia, principalmente a plaquetopenia, do paciente com cirrose poderia estar implicada. O número e a função plaquetária têm particular relevância na manutenção da hemostasia, uma vez que a geração de trombina depende fortemente desses parâmetros. Entretanto, dados demonstram a preservação da função plaquetária como consequência de mecanismos compensatórios representados, pri

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Souza, Maria Claudia de Campos Mello Inglez de. "Desenvolvimento e avaliação de método substitutivo para a prática da hemostasia em cadáveres quimicamente preservados." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-07062013-102925/.

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O aprendizado e o ensino da cirurgia veterinária envolvem o desenvolvimento de habilidades que podem ser obtidas em laboratórios, por meio de vários modelos já disponíveis, incluindo o treinamento em cadáveres. Nestes, quando comparados aos procedimentos em animais vivos, duas limitações são notadas e frequentemente mencionadas, e referem-se às alterações de consistência dos tecidos e à ausência de sangramento durante o treinamento cirúrgico. Este trabalho foi focado na superação destas questões, por meio da realização da simulação de circulação sanguínea em cadáveres adequadamente preservados

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Vieira, Carolina Okamoto. "Mecanismo hemostático da serpente Crotalus durissus terrificus (Ophidia: Viperidae, Crotalinae)." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/41/41135/tde-26012015-141001/.

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A hemostasia previne a perda de sangue após uma lesão vascular e garante a fluidez sanguínea. Para isso há a participação de células carreadoras de fator tissular e também de plaquetas, além de fatores plasmáticos, cofatores, fosfolipídios e íons cálcio que resultam na liberação dos fibrinopeptídios do fibrinogênio e polimerização dos monômeros de fibrina, transformando-os em fibrina estável. Os polifosfatos também participam da ativação da via intrínseca da cascata de coagulação ativando o fator XII e a pré-calicreína plasmática. Os répteis possuem peculiaridades quanto ao mecanismo de coagul

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33

Aguiar, Juliana. "Eletrocoagulação bipolar e monopolar na ovariosalpingohisterectomia videocirurgica híbrida utilizando dois portais em felinos hígidos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/32624.

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Neste trabalho foi realizado um estudo comparativo entre duas técnicas de oclusão do Complexo Artério Venoso Ovariano (CAVO), por meio da eletrocoagulação monopolar e bipolar, na ovariosalpingohisterectomia (OSH) de felinos hígidos, realizada a partir da técnica com dois portais na linha média ventral. A OSH é um dos procedimentos laparoscópicos mais realizados na casuística da Medicina Veterinária. Diferentes técnicas tem sido realizadas para a execução deste procedimento, dentre as variações incluem-se o número e a disposição dos trocartes, sendo recente a execução da técnica com dois portai

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Fall, Lewis. "Redox regulation of haemostasis : modulation by inspiratory hypoxia and physical exercise." Thesis, University of South Wales, 2012. https://pure.southwales.ac.uk/en/studentthesis/redox-regulation-of-haemostasis-modulation-by-inspiratory-hypoxia-and-physical-exercise(712686ec-639c-4d2f-b779-47e1b3b21da1).html.

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Introduction: Haemostasis is the arrest of bleeding. In recent years, in-vitro studies have suggested that secondary haemostasis (blood coagulation) is subject to activation by reactive oxygen species (ROS). It is known that patients who suffer from vascular disease are typically hypoxaemic and in the case of peripheral occlusive artery disease (POAD), physical exercise is used to improve symptom free mobility in the affected limbs. Hypoxia and physical exercise are two potent independent and synergistic initiators of ROS. We identified a clear need for in-vivo analysis of this novel area of r

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Obinwa, Pia. "Stabilitet och hållbarhet av reagens efter nedfrysning och frystorkning för användning vid analys av trombocytfunktion med flödescytometri." Thesis, Linköpings universitet, Institutionen för medicin och hälsa, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130030.

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Introduction: Hemostasis is a complex system in the body that maintains blood flow and prevents bleeding. Patients with platelet disorders are at the risk of mucocutaneous bleedings and at Clinical chemistry in Linköping platelet function is measured with flow cytometry. The platelet response to various agonists is measured with fluorescently labeled platelet antibodies. The aim of this study was to evaluate the stability of the frozen reagents used for platelet function testing. Further the durability of platelet antibodies after freezing and freeze-drying was tested. Method: Platelet antib

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Pripp, Ulla. "The effect of sex hormones on hemostasis and cardiovascular riskfactors in postmenopausal women /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-982-X/.

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Buzała, Mateusz. "Variability of secondary hemostasis in broiler chickens administered in ovo with selected prebiotics." Rozprawa doktorska, Uniwersytet Technologiczno-Przyrodniczy w Bydgoszczy, 2015. http://dlibra.utp.edu.pl/Content/842.

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Celem badań było określenie parametrów krzepnięcia krwi (stężenia całkowitego TF i TFPI oraz aPTT i stężenia fibrynogenu) u kurcząt brojlerów w zależności od ich wieku oraz ocena wpływu podania w wyniku iniekcji in ovo wybranych prebiotyków na zmienność mechanizmów układu hemostazy podczas odchowu kurcząt brojlerów

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Kauhanen, Petteri. "Vascular regulation of hemostasis and fibrinolysis : with special focus on vein graft disease." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/kauhanen/.

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Dore, Celina Maria Pinto Guerra. "Aspectos estruturais, farmacol?gicos e biol?gicos de fucanas da alga marrom sargassum vulgare." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12570.

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Made available in DSpace on 2014-12-17T14:03:35Z (GMT). No. of bitstreams: 1 CelinaMPGD_TESE.pdf: 1816885 bytes, checksum: 1e39ca48cae61af571d696fef8f71be4 (MD5) Previous issue date: 2012-10-15<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>The present study examines the chemical composition and their effects on free radicals, inflammation, angiogenesis, coagulation, VEGF effects and cellular proliferation of a polysaccharides from alga Sargassum vulgare. The sulfated polysaccharide was extracted from brown seaweed by proteolysis with enzymes maxataze. The presence of pr

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Rieger, Alexandre. "Variabilidade genética da hemostasia como fator de risco para as complicações micro e macrovasculares do diabetes mellitus tipo 2." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/28433.

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Introdução: O diabetes mellitus tipo 2 (DM2) representa cerca de 90% dos tipos de diabetes e vem atingindo de forma cada vez mais intensa a população adulta e atualmente também jovens e até crianças. Uma dieta hipercalórica, aliada ao sedentarismo tem sido junto com a predisposição genética os principais desencadeantes das complicações crônicas associadas com o DM2. Infelizmente, são essas complicações que levam ao grande aumento da morbidade e mortalidade que pode chegar até 80% nesta doença, sendo que as principais são as de natureza micro e macrovascular. Complicações microvasculares compre

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Khandekar, Gauri. "Origin and Role of Factor Viia." Thesis, University of North Texas, 2013. https://digital.library.unt.edu/ark:/67531/metadc407814/.

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Factor VII, the initiator of the extrinsic coagulation cascade, circulates in human plasma mainly in its zymogen form, Factor VII and in small amounts in its activated form, Factor VIIa. However, the mechanism of initial generation of Factor VIIa is not known despite intensive research using currently available model systems. Earlier findings suggested serine proteases Factor VII activating protease, and hepsin play a role in activating Factor VII, however, it has remained controversial. In this work I estimated the levels of Factor VIIa and Factor VII for the first time in adult zebrafish pla

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Poliachik, Sandra Louise. "An investigaton of the mechanisms of high intensity focused ultrasound induced platelet activity /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/8011.

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Dudka, I. V. "Condition of hemostasis system in patients with chronic obstructive pulmonary disease and chronic pancreatitis." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18585.

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Baracat, Felipe Iankelevich. "Hemostasia endoscópica para o sangramento da úlcera péptica: revisão sistemática e meta-análises." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5168/tde-28072017-092110/.

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Contexto: A hemorragia digestiva alta (HDA) resulta em 200 a 300 mil internações por ano nos Estados Unidos, com uma mortalidade de 2,5% a 10%. A úlcera péptica representa a causa mais comum de HDA, correspondendo por um terço a metade de todos os casos. Apesar das melhorias na compreensão de sua etiologia, a incidência de sangramento da úlcera péptica, sua complicação mais comum, não se alterou nas últimas décadas. A terapia endoscópica para HDA pode reduzir drasticamente o risco de ressangramento ou sangramento contínuo, a necessidade de cirurgia de urgência, o número de unidades de concentr

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Lino, Ciro Novaes Rosa. "Caracterização da atividade biológica da serpina salivar AET-7393 de Aedes aegypti." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-18032014-181542/.

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Para conseguirem se alimentar com sucesso, os mosquitos hematófagos possuem componentes em sua saliva capazes de regular a hemostasia e modular a imunidade dos hospedeiros. Entretanto, a avaliação das atividades biológicas dessas moléculas no hospedeiro ainda carece de estudos mais aprofundados. No presente projeto, propomos caracterizar as atividades biológicas do produto do transcrito AET-7393, uma serpina presente nas glândulas salivares de fêmeas do mosquito Aedes aegypti. Nossos dados mostram que a serpina AET-7393 recombinante provoca um aumento no sangramento quando inoculada em camundo

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Jones, Tina. "Interventional cardiology: a portfolio of research pertaining to femoral sheath removal practices and patient education." Title page, table of contents and portfolio structure and overview only, 2003. http://web4.library.adelaide.edu.au/theses/09DNS/09dnsj798.pdf.

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"March 2003" Includes bibliographical references (leaves 61-68). Appendices: Publications arising from the research portfolio. 1. Conducting a systematic review -- 2. The effectiveness of mechanical compression devices in attaining hemostasis after removal of a femoral sheath following femoral artery cannulation for cardiac interventional procedures : a systematic review -- 3. Effectiveness of mechanical compression devices in attaining hemostasis after femoral sheath removal Contains three separate research projects, presented as separate reports, but all related to one area of interest - int

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Raghu, Harini. "Mechanisms Coupling Hemostatic Factors to Inflammatory Arthritis." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900762.

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Leme, Junior Paulo de Tarso de Oliveira. "MÚSCULO AUTÓGENO NA HEMOSTASIA TEMPORÁRIA DO PLEXO VENOSO VERTEBRAL VENTRAL DE COELHOS SUBMETIDOS Á HEMILAMINECTOMIA TORACOLOMBAR." Universidade Federal de Santa Maria, 2012. http://repositorio.ufsm.br/handle/1/10145.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The objective of this experiment was to document the postoperative evolution of New Zealand rabbits that underwent a hemi laminectomy surgery (T13-L1) and received a graft of autogenous muscle as an hemostatic agent into the spinal canal. These animals were followed for a period of 14 and 28 days with daily neurological assessments and, at the end of their follow-up period, were euthanized in order to remove the graft site to be examined microscopically. The animals were divided into 6 groups such as the control group A and B, C

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Morrow, Gael Beverley. "Platelets harbour pro- and anti-fibrinolytic proteins on their activated membrane surface that regulate fibrinolysis of thrombi formed under flow." Thesis, University of Aberdeen, 2018. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=237022.

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Platelets play an essential role in haemostasis by adhering to the damaged vessel wall and forming a platelet plug to arrest bleeding. Although platelets are traditionally thought of as pro-coagulant, they possess the ability to harbour functional proteins that are key to fibrinolysis, the breakdown of the blood clot, on their surface. They are therefore substantially well equipped to regulate local fibrinolysis. This thesis aims to further define the role of platelets in fibrinolysis, in particular platelet-derived plasminogen activator inhibitor 1 (PAI-1) and plasminogen. PAI-1 is the princi

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Carter, Tiffany. "Hemostatic efficiency of amphiphilic peptide solution in Wistar Rat model." Thesis, Kansas State University, 2014. http://hdl.handle.net/2097/35239.

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Master of Science<br>Department of Grain Science and Industry<br>X. Susan Sun<br>One of the leading causes of death following traumatic injury is exsanguination. The body addresses bleeding through the process of hemostasis which includes the formation of a fibrin mesh structure that holds a blood clot together. During traumatic injury, hemostasis may be unable to stop excess bleeding. Fibrin based hemostatic agents have been developed, however, these studies often use fibrin obtained from biological sources, which poses risk of infection. A novel amphiphilic peptide (h9e) has been studied to

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