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Journal articles on the topic 'Hemothorax and malignant effusions'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Olsen, Diana, Charlene Molloy, and P. S. Sriram. "Rapidly Progressive Lung Cysts and Pleural Effusion: A Case Report." Case Reports in Pulmonology 2011 (2011): 1–3. http://dx.doi.org/10.1155/2011/790274.

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Angiosarcoma is a rare but highly malignant tumor arising from vascular endothelial cells. Angiosarcoma commonly arises from the heart, liver, breast, and skin including the scalp. Angiosarcoma metastasizing to the lungs can present as either pneumothorax, hemothorax, or pleural effusions. They can rarely present as rapidly enlarging thin-walled pulmonary cysts. A review of the literature is included.

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2

Argento, Angela Christine, and Colin T. Gillespie. "Pleural Disease in Women." Seminars in Respiratory and Critical Care Medicine 40, no. 03 (2019): 402–9. http://dx.doi.org/10.1055/s-0039-1695050.

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AbstractThere are several pleural diseases that occur either predominantly or exclusively in females. Most of these entities are related to obstetric or gynecological conditions. In this article, we will provide an overview of Meigs' syndrome, ovarian hyperstimulation syndrome, endometriosis, catamenial pneumothorax, catamenial hemothorax, pleural effusions that occur in the peripartum period, lymphangioleiomyomatosis, and malignant pleural effusions related to breast cancer. As most of these diagnoses are rare, considerable expertise is required to identify, diagnose, and manage these patient

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3

Tajarernmuang, Pattraporn, Anne V. Gonzalez, David Valenti, and Stéphane Beaudoin. "Overuse of small chest drains for pleural effusions: a retrospective practice review." International Journal of Health Care Quality Assurance 34, no. 2 (2021): 73–82. http://dx.doi.org/10.1108/ijhcqa-11-2020-0231.

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PurposeSmall-bore drains (≤ 16 Fr) are used in many centers to manage all pleural effusions. The goal of this study was to determine the proportion of avoidable chest drains and associated complications when a strategy of routine chest drain insertion is in place.Design/methodology/approachWe retrospectively reviewed consecutive pleural procedures performed in the Radiology Department of the McGill University Health Centre over one year (August 2015–July 2016). Drain insertion was the default drainage strategy. An interdisciplinary workgroup established criteria for drain insertion, namely: pn

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4

George, Rhea Sarah, and Manna Liz George. "A rare case report of a young female patient with thymoma presenting as hemothorax and hemopericardium." International Journal of Research in Medical Sciences 13, no. 6 (2025): 2634–36. https://doi.org/10.18203/2320-6012.ijrms20251659.

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Thymoma is a rare neoplasm affecting adults between the fourth and sixth decades of life. Although its mostly diagnosed incidentally, there has been rare cases presenting with hemothorax or hemopericardium. We describe the case history of a 31-year-old Asian female presenting with sudden onset breathlessness and sharp chest pain with chest X-ray and ECHO consistent of massive pericardial effusion and bilateral pleural effusion. Fluid analysis showed plenty of RBC without any evidence of malignant cells. CECT Thorax showed an anterior mediastinal mass whose histopathology confirmed a type AB Th

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5

AlShati, Mohammed H., Ramesh Kumar, and Shreeram Kannan. "Dyspnea, Massive Effusion and Lytic Rib Lesion as Initial Presentation of Multiple Myeloma in a Young Man." Canadian Respiratory Journal 20, no. 4 (2013): 253–55. http://dx.doi.org/10.1155/2013/242045.

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Multiple myeloma, a disorder commonly encountered in elderly patients, represents a malignant proliferation of plasma cells that primarily affects bone marrow. Pleural effusion as the presenting manifestation of the disease is uncommon. The authors report a case of multiple myeloma with unusual features presenting at a relatively young age with massive spontaneous hemothorax and multiple thoracic masses completely obscuring rib shadow on plain chest imaging. The patient demonstrated a good response to melphalan chemotherapy without recurrence of effusion or the need for additional chemical or

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6

Zeeshan Ashraf and Muhammad Ashraf. "Short comparison of talc poudrage and tetracycline pleurodesis within patients suffering from malignant pleural effusion." Professional Medical Journal 30, no. 12 (2023): 1561–66. http://dx.doi.org/10.29309/tpmj/2023.30.12.7846.

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Objective: To compare talc poudrage and tetracycline pleurodesis within patients suffering from malignant pleural effusion. Study Design: Controlled Clinical Trial. Setting: Division of Pulmonology, Jinnah Hospital Lahore. Period: September, 2022 up until May, 2023. Material & Methods: 100 individuals, both male and female, ranging in age from 20 to 80 years, diagnosed with malignant pleural effusion confirmed on biopsy were included by nonprobability consecutive sampling. Patients with active pleural infection, hemodynamic instability, systemic infection, serum hematocrit < 25%, hemoth

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7

International, Journal of Medical Science and Innovative Research (IJMSIR). "A Comparative Study To Assess The Knowledge Among Final Year B. Se Nursing and Final Year G.N.M Students on Care of Chest Tube Drainage in Selected Institutions at Bangalore." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 4 (2024): 118–33. https://doi.org/10.5281/zenodo.15423194.

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<strong>Abstract</strong> <strong>Introduction and Objectives: </strong>Ventilation is the flow of gas in and out of the lungs. Adequate gas exchange depends on a effective ventilation. The normal breathing mechanism operates on the principle of negative pressure; that is, the pressure in the chest cavity normally is lower than the pressure of the atmosphere, causing air to move into the lung. The collection of air, fluid, or other substances in the chest can compromise cardiopulmonary function and can also cause the lung to collapse. Pathologic substances that collect in the pleural space inc

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8

Devraj, Mayur, Chaitanya Kappagantu, Sushma Dugad, Ravidra Shinde, and Komal Shah. "An aberrant presentation of non-hodgkin’s lymphoma as pus: A curious journey." IP Indian Journal of Immunology and Respiratory Medicine 7, no. 4 (2023): 173–75. http://dx.doi.org/10.18231/j.ijirm.2022.039.

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T-lymphoblastic lymphoma (T-LBL) is most commonly found in younger age group and rare. It is most aggressive form ofnon-Hodgkin’s lymphoma. T-lymphoblastic lymphoma (T-LBL) response rate to chemotherapy is very good although relapse is common with poor survival rates.A 25 years old female presented to emergency department of a tertiary care centre with dyspnoea and chest tube in left Hemothorax in situ. She had earlier history of pulmonary tuberculosis 3 years back and took anti tubercular treatment for 6 months. On general examination we found left supraclavicular lymphadenopathy of size 2 ×

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9

Salehiazar, S., K. Mirzaei Baboli, R. Chiu, and C. G. Yap. "Case Report: Aspirated Airway Foreign Body Mimicking Endobronchial Mass: A Diagnostic Challenge." American Journal of Clinical Pathology 162, Supplement_1 (2024): S27—S28. http://dx.doi.org/10.1093/ajcp/aqae129.060.

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Abstract Introduction/Objective Despite advancements in imaging modalities, identifying retained foreign bodies within the lung remains arduous. Detecting small foreign bodies is crucial as they can serve as a focal point for subsequent infections. Initial assessments may mimic malignancy. Herein, we present a case of a retained foreign body masquerading as an endobronchial mass, accompanied by unilateral pleural effusion and persistent hypoxia. Subsequent bronchoscopy showed a pearly white endobronchial mass partially obstructing the segmental bronchus at the posterior basal segment of the ri

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10

AlQatari, Abdullah, Ayesha Ahmed, Fatima AlHije, Mohammed Sabry, and Hatem Elbawab. "Primary Pulmonary Synovial Sarcoma with Hemothorax: a Case Report." Medical Archives 77, no. 6 (2023): 496. http://dx.doi.org/10.5455/medarh.2023.77.496-499.

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Background: Synovial sarcoma is a rare and aggressive soft tissue malignancy most commonly arises from periarticular tissue of the extremities. Although several cases in the literature have reported different origins, primary pulmonary synovial sarcoma (PPSS) is an exceedingly rare and underrecognized entity, accounting for 0.5% of all lung malignancies. Clinical presentation includes chest pain, dyspnea, cough, and hemoptysis. The finding of hemothorax is a rare presentation and was barely reported in the literature. Due to its rarity and aggressive nature, the optimal treatment is unclear, w

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11

Olopade, O. I., and J. E. Ultmann. "Malignant effusions." CA: A Cancer Journal for Clinicians 41, no. 3 (1991): 166–79. http://dx.doi.org/10.3322/canjclin.41.3.166.

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12

Oommen, R. "Malignant Effusions." Journal of Clinical Pathology 49, no. 10 (1996): 865. http://dx.doi.org/10.1136/jcp.49.10.865-b.

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13

Bedrossian, E. W. M., and Suzanne M. Selvaggi. "Malignant Effusions." American Journal of Surgical Pathology 19, no. 2 (1995): 243. http://dx.doi.org/10.1097/00000478-199502000-00023.

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14

Divisi, Duilio, and Roberto Crisci. "Malignant pleural effusions." Journal of Xiangya Medicine 6 (March 2021): 1. http://dx.doi.org/10.21037/jxym-20-121.

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15

Sahn, Steven A. "Malignant Pleural Effusions." Clinics in Chest Medicine 6, no. 1 (1985): 113–25. http://dx.doi.org/10.1016/s0272-5231(21)00343-9.

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16

Kapp, Christopher M., and Hans J. Lee. "Malignant Pleural Effusions." Clinics in Chest Medicine 42, no. 4 (2021): 687–96. http://dx.doi.org/10.1016/j.ccm.2021.08.004.

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17

Lee, Y. C. Gary, and Sylwia Wilkosz. "Malignant Pleural Effusions." American Journal of Respiratory and Critical Care Medicine 178, no. 1 (2008): 3–5. http://dx.doi.org/10.1164/rccm.200804-616ed.

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18

Hott, Jeffrey. "Malignant Pleural Effusions." Seminars in Respiratory and Critical Care Medicine 16, no. 04 (1995): 333–39. http://dx.doi.org/10.1055/s-2007-1009844.

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19

Frankel, Kenneth M. "Malignant Pericardial Effusions." Chest 126, no. 5 (2004): 1713. http://dx.doi.org/10.1378/chest.126.5.1713.

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20

Sahn, Steven A. "Malignant Pleural Effusions." Seminars in Respiratory and Critical Care Medicine 22, no. 06 (2001): 607–16. http://dx.doi.org/10.1055/s-2001-18796.

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21

Prakash, Udaya B. S. "Malignant pleural effusions." Postgraduate Medicine 80, no. 5 (1986): 201–9. http://dx.doi.org/10.1080/00325481.1986.11699569.

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22

WALSH, FRANK W., W. MICHAEL ALBERTS, DAVID A. SOLOMON, and ALLAN L. GOLDMAN. "Malignant Pleural Effusions." Southern Medical Journal 82, no. 8 (1989): 963–65. http://dx.doi.org/10.1097/00007611-198908000-00008.

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23

Patz, Edward F. "Malignant Pleural Effusions." Chest 113, no. 1 (1998): 74S—77S. http://dx.doi.org/10.1378/chest.113.1_supplement.74s.

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24

Sahn, Steven. "Malignant Pleural Effusions." Seminars in Respiratory and Critical Care Medicine 9, no. 01 (1987): 43–53. http://dx.doi.org/10.1055/s-2007-1012687.

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25

Putnam, Joe B. "Malignant pleural effusions." Surgical Clinics of North America 82, no. 4 (2002): 867–83. http://dx.doi.org/10.1016/s0039-6109(02)00036-1.

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26

Grannis, Frederic W., Carey A. Cullinane, and I. Benjamin Paz. "Malignant Pericardial Effusions." Chest 126, no. 5 (2004): 1713. http://dx.doi.org/10.1016/s0012-3692(15)31405-7.

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27

Haas, Andrew R., Daniel H. Sterman, and Ali I. Musani. "Malignant Pleural Effusions." Chest 132, no. 3 (2007): 1036–41. http://dx.doi.org/10.1378/chest.06-1757.

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28

Reeder, Laurie B. "Malignant pleural effusions." Current Treatment Options in Oncology 2, no. 1 (2001): 93–96. http://dx.doi.org/10.1007/s11864-001-0020-x.

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29

Thomas, Justin M., and Ali I. Musani. "Malignant Pleural Effusions." Clinics in Chest Medicine 34, no. 3 (2013): 459–71. http://dx.doi.org/10.1016/j.ccm.2013.05.004.

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30

West, Howard (Jack). "Malignant Pleural Effusions." JAMA Oncology 1, no. 2 (2015): 260. http://dx.doi.org/10.1001/jamaoncol.2015.0671.

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31

Irani, Dina R. "Malignant Pleural Effusions." Archives of Internal Medicine 147, no. 6 (1987): 1133. http://dx.doi.org/10.1001/archinte.1987.00370060129021.

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32

Wang, Li-feng, Hai-tao Yin, Xiao-ping Qian, et al. "Beta-Tubulin III mRNA expression and docetaxel sensitivity in non-small cell lung cancer." Clinical & Investigative Medicine 32, no. 6 (2009): 278. http://dx.doi.org/10.25011/cim.v32i6.10663.

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Purpose: Despite the success of docetaxel as an anti-tumour agent, the inter-individual variability in drug response still poses a major impediment to further use of this agent in the treatment of cancer. Current knowledge about predictive biomarkers of docetaxel sensitivity in malignant effusions is poor. The aim of this study was to investigate the association between ?-tubulin III mRNA expression and chemosensitivity to docetaxel in metastatic malignant effusions. Methods: Real-time quantitative PCR was used for analysis of ?-tubulin III mRNA expression in 37 malignant effusions collected p

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33

Ganguli, Amitava, Lauren Walker, Richard Joaquim FitzGerald, and Munir Pirmohamed. "Spontaneous Hemothorax Following Anticoagulation with Low-Molecular-Weight Heparin." Annals of Pharmacotherapy 43, no. 9 (2009): 1528–31. http://dx.doi.org/10.1345/aph.1l542.

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Objective: To report a case of spontaneous hemothorax following anticoagulation with low-molecular-weight heparin (LMWH) for the management of suspected pulmonary embolism. Case Summary: A 66-year-old man with a background history of breast carcinoma was admitted with pleuritic chest pain. He was initially managed as a suspected case of pulmonary embolism. Dalteparin, an LMWH, was started at a maximum dose of 18,000 units subcutaneously once daily, according to British national prescribing guidelines. On day 4, following 3 doses of dalteparin, the patient developed acute respiratory distress a

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34

West, Pamela J., and Melodie Cannon. "Heartaches: Malignant Pericardial Effusions." Oncology Nursing Forum 40, no. 4 (2013): 315–17. http://dx.doi.org/10.1188/13.onf.315-317.

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35

Lui, Macy M. S., Deirdre B. Fitzgerald, and Y. C. Gary Lee. "Phenotyping malignant pleural effusions." Current Opinion in Pulmonary Medicine 22, no. 4 (2016): 350–55. http://dx.doi.org/10.1097/mcp.0000000000000267.

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36

Thai, Vincent. "Malignant Pericardial Effusions #209." Journal of Palliative Medicine 12, no. 11 (2009): 1052–53. http://dx.doi.org/10.1089/jpm.2009.9937.

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37

Mansi, J. L., and G. W. Hanks. "DRAINAGE OF MALIGNANT EFFUSIONS." Lancet 334, no. 8653 (1989): 43. http://dx.doi.org/10.1016/s0140-6736(89)90279-1.

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38

Dresler, Carolyn M. "6. Malignant pleural effusions." Current Problems in Cancer 20, no. 3 (1996): 213–16. http://dx.doi.org/10.1016/s0147-0272(96)80309-6.

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39

Yellin, Alon. "Doxycycline for malignant effusions." Annals of Thoracic Surgery 57, no. 4 (1994): 1053. http://dx.doi.org/10.1016/0003-4975(94)90246-1.

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40

Chandra, Mithilesh. "Immunocytochemistry of malignant effusions." Journal of Cytology 12, no. 1 (1995): 9. http://dx.doi.org/10.4103/0970-9371.237240.

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41

Berger, Eric G., E. F. Holdener, K. L. Hoyt, and A. J. Gehler. "Galactosyltransferase in malignant effusions." European Journal of Cancer and Clinical Oncology 21, no. 3 (1985): 402. http://dx.doi.org/10.1016/0277-5379(85)90146-4.

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42

Xie, L., X. Chen, X. Qian, et al. "Cell-free miR-10b and miR-21 as diagnostic biomarkers for malignant effusions." Journal of Clinical Oncology 27, no. 15_suppl (2009): 11035. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.11035.

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11035 Background: Numerous studies have proved the roles of tissue microRNAs (miRNAs) as biomarkers in cancer diagnosis. Cell-free miRNAs from plasma or serum have been shown to be good biomarkers in the diagnosis of cancers. Here we tried to explore the potential application of cell-free miRNAs as diagnostic biomarkers to discriminate malignant effusions from benign. Methods: To obtain a molecular signature for malignant effusions, a stem-loop real-time PCR was adopted to measure the expression of 23 tumor-related miRNAs. After a pre-screening for discarding low amount miRNAs in 10 samples (5

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43

Karki, S., A. Jha, and G. Sayami. "The Role of Argyrophilic Nucleolar Organizer Region (AgNOR) Study in Cytological Evaluation of Fluids, Especially for Detection of Malignancy." Kathmandu University Medical Journal 10, no. 1 (2012): 34–39. http://dx.doi.org/10.3126/kumj.v10i1.6913.

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Background Serous effusion smears reported as “suspicious for malignancy” pose problems in clinical management. Silver staining for argyrophilic nucleolar organizer regions (AgNOR) has proved useful in making a cytopathologic differential diagnosis between benign and malignant cells. Nucleolar organizer regions(NORs) are loops of DNA located in acrocentric chromosomes. These NORs are visualized by silver staining technique that recognizes these argyrophilia associated proteins which are increased in malignancy. Objective This study aimed to distinguish reactive mesothelial cells from malignant

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44

Oh, Scott, Reza Ronaghi, and Guoping Cai. "Molecular Testing on Pleural Fluid Samples." Seminars in Respiratory and Critical Care Medicine 40, no. 03 (2019): 340–46. http://dx.doi.org/10.1055/s-0039-1695702.

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AbstractPleural effusions are a common manifestation of both malignant and nonmalignant diseases. The sampling of pleural fluid helps categorize effusions as transudative or exudative and helps differentiate paramalignant from malignant disease. Accurate pleural fluid analysis is critical to the appropriate staging of cancers with significant prognostic and treatment implications. However, the etiology of pleural effusions remains unclear in a significant number of cases after routine thoracentesis and pleural fluid analysis. For malignant pleural effusions, cytologic evaluation of pleural flu

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45

Zamora-Molina, Lucía, Eduardo García-Pachon, Marta Amorós, et al. "Transcriptomic Profiling of Pleural Effusions: Differences in Malignant and Infectious Fluids." Medicina 60, no. 3 (2024): 424. http://dx.doi.org/10.3390/medicina60030424.

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Background and Objectives: Different cellular and molecular processes are involved in the production of malignant and infectious pleural effusions. However, the underlying mechanisms responsible for these differences or their consequences remain incompletely understood. The objective of this study was to identify differences in gene expression in pleural exudates of malignant and infectious aetiology and establish the possible different biological processes involved in both situations. Materials and Methods: RNA transcriptomic analysis was performed on 46 pleural fluid samples obtained during

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46

Kenia, Hernández Mejía, Antonio Calixto Estanislao, Díaz Aguilar Leopoldo, Sandoval Sánchez David, de Jesús Aguirre Linares Mariely, and José Santana Cano María. "Hemothorax Due to Aneurysm of the Left Pulmonary Vein in a Pregnant Patient. Case Report." International Journal Of Medical Science And Clinical Research Studies 02, no. 12 (2022): 1482–83. https://doi.org/10.5281/zenodo.7427296.

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  Pulmonary venous aneurysm often presents as a mediastinal mass, in most cases patients are asymptomatic and surgical treatment is not required unless there are complications. We present the case of a 34-year-old woman, with a normal evolutionary pregnancy of 36 weeks of gestation, with dyspnea on small to medium efforts, to which was added pleuritic pain in the left hemithorax, evidence of left pleural effusion greater than 80%, with drainage of 700 ml of hematic fluid. The gynecology and obstetrics service identified anhydramnios, deciding to terminate the pregnancy through the abdomen

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47

Gonlugur, Tanseli E., and Ugur Gonlugur. "Transudates in Malignancy: Still a Role for Pleural Fluid." Annals of the Academy of Medicine, Singapore 37, no. 9 (2008): 760–63. http://dx.doi.org/10.47102/annals-acadmedsg.v37n9p760.

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Introduction: The aims of this study were to determine the distribution of transudates and exudates among pathologically proven malignant pleural effusions, and to demonstrate the necessity for cytologic studies in patients with a transudative effusion. Materials and Methods: This study is a retrospective review of all subjects diagnosed with malignant or paramalignant pleural effusion over a 10-year period at a tertiary hospital. The study included 67 subjects with malignant mesothelioma, 45 subjects with metastatic disease, and 36 subjects with paramalignant effusions. Results: There were 55

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48

Cakir, Ebru, Funda Demirag, Mehtap Aydin, and Yurdanur Erdogan. "A review of uncommon cytopathologic diagnoses of pleural effusions from a chest diseases center in Turkey." CytoJournal 8 (July 16, 2011): 13. http://dx.doi.org/10.4103/1742-6413.83026.

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Background: After pneumonia, cancer involving the pleura is the leading cause of exudative pleural effusion. Cytologic examination of pleural effusions is an important initial step in management of malignant effusions. The aim of this study is to evaluate the spectrum of uncommon malignant pleural effusions in a chest disease center in Turkey. Materials and Methods: A retrospective study of samples of pleural effusions submitted to Ataturk Chest Diseases and Chest Surgery Education and Research Hospital Department of Pathology between March 2005 and November 2008 was performed. Results: Out of

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49

Aujayeb, Avinash, and Donna Wakefield. "Fatigue and malignant pleural effusions." BMJ Supportive & Palliative Care 11, no. 3 (2021): 305. http://dx.doi.org/10.1136/bmjspcare-2021-002955.

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50

Grossi, Francesco, Maria Cristina Pennucci, Lucia Tixi, Mara A. Cafferata, and Andrea Ardizzoni. "Management of Malignant Pleural Effusions." Drugs 55, no. 1 (1998): 47–58. http://dx.doi.org/10.2165/00003495-199855010-00004.

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