Relevant bibliographies by topics / Hendra

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Hendra'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 February 2022

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Journal articles on the topic "Hendra"

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Young, Jeannette R., Christine E. Selvey, and Rick Symons. "Hendra virus." Medical Journal of Australia 195, no. 5 (September 2011): 250–51. http://dx.doi.org/10.5694/mja11.10967.

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Middleton, Deborah. "Hendra Virus." Veterinary Clinics of North America: Equine Practice 30, no. 3 (December 2014): 579–89. http://dx.doi.org/10.1016/j.cveq.2014.08.004.

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BARCLAY, A. J., and D. J. PATON. "Hendra (Equine Morbillivirus)." Veterinary Journal 160, no. 3 (November 2000): 169–76. http://dx.doi.org/10.1053/tvjl.2000.0508.

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Meulendyke, Kelly Ann, Mark Allen Wurth, Richard O. McCann, and Rebecca Ellis Dutch. "Endocytosis Plays a Critical Role in Proteolytic Processing of the Hendra Virus Fusion Protein." Journal of Virology 79, no. 20 (October 15, 2005): 12643–49. http://dx.doi.org/10.1128/jvi.79.20.12643-12649.2005.

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ABSTRACT The Hendra virus fusion (F) protein is synthesized as a precursor protein, F0, which is proteolytically processed to the mature form, F1+F2. Unlike the case for the majority of paramyxovirus F proteins, the processing event is furin independent, does not require the addition of exogenous proteases, is not affected by reductions in intracellular Ca2+, and is strongly affected by conditions that raise the intracellular pH (C. T. Pager, M. A. Wurth, and R. E. Dutch, J. Virol. 78:9154-9163, 2004). The Hendra virus F protein cytoplasmic tail contains a consensus motif for endocytosis, YXXΦ. To analyze the potential role of endocytosis in the processing and membrane fusion promotion of the Hendra virus F protein, mutation of tyrosine 525 to alanine (Hendra virus F Y525A) or phenylalanine (Hendra virus F Y525F) was performed. The rate of endocytosis of Hendra virus F Y525A was significantly reduced compared to that of the wild-type (wt) F protein, confirming the functional importance of the endocytosis motif. An intermediate level of endocytosis was observed for Hendra virus F Y525F. Surprisingly, dramatic reductions in the rate of proteolytic processing were observed for Hendra virus F Y525A, although initial transport to the cell surface was not affected. The levels of surface expression for both Hendra virus F Y525A and Hendra virus F Y525F were higher than that of the wt protein, and these mutants displayed enhanced syncytium formation. These results suggest that endocytosis is critically important for Hendra virus F protein cleavage, representing a new paradigm for proteolytic processing of paramyxovirus F proteins.
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Pager, Cara Theresia, Mark Allen Wurth, and Rebecca Ellis Dutch. "Subcellular Localization and Calcium and pH Requirements for Proteolytic Processing of the Hendra Virus Fusion Protein." Journal of Virology 78, no. 17 (September 1, 2004): 9154–63. http://dx.doi.org/10.1128/jvi.78.17.9154-9163.2004.

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ABSTRACT Proteolytic cleavage of the Hendra virus fusion (F) protein results in the formation of disulfide-linked F1 and F2 subunits, with cleavage occurring after residue K109 in the sequence GDVK↓L. This unusual cleavage site and efficient propagation of Hendra virus in a furin-deficient cell line indicate that the Hendra F protein is not cleaved by furin, the protease responsible for proteolytic activation of many viral fusion proteins. To identify the subcellular site of Hendra F processing, Vero cells transfected with pCAGGS-Hendra F or pCAGGS-SV5 F were metabolically labeled and chased in the absence and presence of inhibitors of exocytosis. The addition of carbonyl-cyanide-3-chlorophenylhydrazone, monensin, brefeldin A, or NaF-AlCl3 or incubation of cells at 20°C all inhibited processing of the Hendra F protein, suggesting that cleavage of Hendra F occurs either in secretory vesicles budding from the trans-Golgi network or at the cell surface. In contrast to proteolytic cleavage of the simian virus 5 (SV5) F protein by the Ca2+-dependent protease furin, proteolytic cleavage of the Hendra F protein was not significantly inhibited by decreases in Ca2+ levels following incubation with EGTA or A23187. However, in the presence of weak amines and H+ V-ATPase inhibitors, known to raise intracellular pH, cleavage of Hendra F protein was inhibited while processing of the SV5 F protein was not significantly affected. The subcellular location, sensitivity to pH changes, and decreased Ca2+ requirement suggest that the protease responsible for cleavage of Hendra F protein differs from proteases previously shown to be involved in the processing of other viral glycoproteins.
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Field, Hume. "Hendra virus re-visited." Virologica Sinica 24, no. 2 (April 2009): 105–9. http://dx.doi.org/10.1007/s12250-009-3034-3.

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Quealy-Gainer, Kate. "Cake by Sue Hendra." Bulletin of the Center for Children's Books 72, no. 6 (2019): 256–57. http://dx.doi.org/10.1353/bcc.2019.0101.

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Berglind, Natalie. "Supertato by Sue Hendra." Bulletin of the Center for Children's Books 73, no. 11 (2020): 477. http://dx.doi.org/10.1353/bcc.2020.0463.

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PÁEZ, D. J., J. GILES, H. MCCALLUM, H. FIELD, D. JORDAN, A. J. PEEL, and R. K. PLOWRIGHT. "Conditions affecting the timing and magnitude of Hendra virus shedding across pteropodid bat populations in Australia." Epidemiology and Infection 145, no. 15 (September 25, 2017): 3143–53. http://dx.doi.org/10.1017/s0950268817002138.

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SUMMARYUnderstanding infection dynamics in animal hosts is fundamental to managing spillover and emergence of zoonotic infections. Hendra virus is endemic in Australian pteropodid bat populations and can be lethal to horses and humans. However, we know little about the factors driving Hendra virus prevalence in resevoir bat populations, making spillover difficult to predict. We use Hendra virus prevalence data collected from 13 000 pooled bat urine samples across space and time to determine if pulses of prevalence are periodic and synchronized across sites. We also test whether site-specific precipitation and temperature affect the amplitude of the largest annual prevalence pulses. We found little evidence for a periodic signal in Hendra virus prevalence. Although the largest amplitude pulses tended to occur over winter, pulses could also occur in other seasons. We found that Hendra virus prevalence was weakly synchronized across sites over short distances, suggesting that prevalence is driven by local-scale effects. Finally, we found that drier conditions in previous seasons and the abundance of Pteropus alecto were positively correlated with the peak annual values of Hendra virus prevalence. Our results suggest that in addition to seasonal effects, bat density and local climatic conditions interact to drive Hendra virus infection dynamics.
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M. Rafiek, M. Rafiek. "PEMASYARAKATAN BAHASA INDONESIA MELALUI MADIHIN BANJAR JHON TRALALA DAN HENDRA SEBAGAI UPAYA MEMPERERAT PERSATUAN BANGSA INDONESIA (THE SOCIALIZATION OF INDONESIAN LANGUAGE THROUGH MADIHIN BANJAR BY JHON TRALALA AND HENDRA AS EFFORTS TO STRENGTHEN NATIONAL UNITY OF INDONESIA)." JURNAL BAHASA, SASTRA DAN PEMBELAJARANNYA 3, no. 2 (March 1, 2018): 184. http://dx.doi.org/10.20527/jbsp.v3i2.4552.

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AbstractThe Socialization of Indonesian Language through Madihin Banjar by Jhon Tralalaand Hendra as Efforts to Strengthen National Unity of Indonesia.Madihin Banjar hostedby Jhon Tralala quite known in Indonesia. Jhon Tralala and Hendra, his son is able toadjust the language of poetry or rhyme madihin that brought the audience in attendancein front of him. When many people Banjar, of language poetry or rhymes that broughtmadihin Banjar language. However, when appearing before the lot is not the Banjar,Jhon Tralala and Hendra, Indonesian children will use in its presentation. Things likethis that make madihin Banjar Jhon Tralala and Hendra, his son is able to be acceptedby the people of Indonesia. Through poems or rhymes that speak Indonesian madihinJhon Tralala and Hendra, his son is able to disseminate ideas, ideas, and messages tostrengthen national unity of Indonesia.Keywords: madihin, indonesian, unifyingAbstrakPemasyarakatan Bahasa Indonesia melalui Madihin Banjar Jhon Tralala dan Hendrasebagai Upaya Mempererat Persatuan Bangsa Indonesia. Madihin Banjar yangdibawakan oleh Jhon Tralala cukup dikenal di Indonesia. Jhon Tralala dan Hendra,anaknya mampu menyesuaikan bahasa syair atau pantun madihin yang dibawakannyadengan khalayak yang hadir di hadapannya. Bila banyak orang Banjar, tentu bahasasyair atau pantun madihin yang dibawakannya menggunakan bahasa Banjar. Akantetapi bila yang hadir di hadapan lebih banyak bukan orang Banjar, Jhon Tralala danHendra, anaknya akan menggunakan bahasa Indonesia dalam penyajiannya. Halseperti inilah yang membuat madihin Banjar Jhon Tralala dan Hendra, anaknya mampuditerima oleh masyarakat Indonesia. Melalui syair atau pantun madihin berbahasaIndonesia itulah Jhon Tralala dan Hendra, anaknya mampu menyebarluaskan ide,gagasan, dan pesan-pesannya untuk mempererat persatuan dan kesatuan bangsaIndonesia.Kata-kata kunci: madihin, bahasa indonesia, pemersatu bangsa
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Dissertations / Theses on the topic "Hendra"

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Field, Hume. "The ecology of Hendra virus and Australian bat lyssavirus /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18575.pdf.

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Kairytė, Ieva. "Monokloninių antikūnų prieš Hendra ir Nipah virusų nukleokapsidės baltymus gavimas ir charakterizavimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2008. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2008~D_20080625_122938-82635.

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Šio darbo tikslas buvo gauti monokloninius antikūnus prieš Hendra ir Nipah virusų nukleokapsidės baltymus. Dėl didelės Henipavirus genties virusų nukleokapsidės baltym�� homologijos sunku gauti monokloninius antikūnus, specifiškus konkretaus viruso nukleokapsidės baltymui. Siekiant išspręsti šią problemą, buvo panaudoti chimeriniai rekombinantiniai baltymai, sukonstruoti pelės poliomos viruso pagrindinio kapsidės baltymo VP1 pagrindu, į kurį buvo įterptos nehomologiškos Nipah ir Hendra virusų nukleokapsidės baltymų sekos. Imunizacijoms panaudojus tokius chimerinius baltymus, buvo nustatyta, kad jie sukelia stiprų imuninį atsaką. Buvo sukurti nauji monokloniniai antikūnai, specifiški tik Nipah viruso nukleokapsidės baltymui ir nereaguojantys su Hendra viruso nukleokapsidės baltymu. Taip pat buvo sukurti monokloniniai antikūnai prieš baltymą-nešiklį – pelės poliomos viruso pagrindinį kapsidės baltymą VP1. Naujai sukurtų antikūnų specifiškumas buvo patvirtintas imunofermentinės analizės ir imunoblotingo metodais. Monokloninių antikūnų prieš Hendra viruso nukleokapsidės baltymą gauti nepavyko.
The aim of this study was to generate monoclonal antibodies against Hendra and Nipah virus nucleocapsid proteins. There is high homology between nucleocapsid proteins of Henipavirus genus members, therefore it is difficult to generate monoclonal antibodies that do not show any cross-reactivity with both antigens. This problem was solved by using recombinant chimeric proteins designed by insertion of non-homological segments of Hendra and Nipah virus nucleocapsid proteins into the mouse polyomavirus capsid protein VP1. Mice were immunized with these chimeric proteins and it was determined that they induce a strong immune response. Monoclonal antibodies against Nipah virus nucleocapsid protein as well as carrier protein – mouse polyomavirus capsid protein VP1 – were generated. The specificities of newly developed monoclonal antibodies were confirmed by ELISA and immunoblot. The generation of specific monoclonal antibodies against Hendra virus nucleocapsid protein failed.
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Resch, Martina [Verfasser], and Gerd [Akademischer Betreuer] Sutter. "Untersuchung rekombinanter Modifizierter Vacciniaviren Ankara hinsichtlich ihrer Eignung als Hendra-Virus-spezifische Impfstoffkandidaten / Martina Resch ; Betreuer: Gerd Sutter." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1168590973/34.

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Habchi, Johnny. "Flexibilité au sein de la nucléoprotéine et de la phosphoprotéine des Paramyxovirus : prédiction, caractérisation expérimentale et repliement induit." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM4091.

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Les virus Nipah (NiV) et Hendra (HeV) appartiennent au genre Henipavirus au sein de la famille des Paramyxoviridae. Cette famille comporte de nombreux pathogènes tel que le virus de la rougeole (MeV). Les paramyxovirus possèdent un génome de type ARN simple brin encapsidé par la nucléoprotéine (N) au sein d'une nucléocapside hélicoïdale. N interagit avec la phosphoprotéine (P) et cette dernière recrute la polymérase (L) qui assure la transcription et la réplication du génome viral. L'objectif de mon projet de thèse était de caractériser les protéines N et P ainsi que les interactions qui existent entre elles chez les trois virus, NiV, HeV et MeV. A la différence du MeV, qui a été intensivement étudié au cours des dernières années, les données moléculaires et structurales sur les Henipavirus étaient très limitées. A l'aide d'analyses computationnelles, nous avons pu déchiffrer l'organisation modulaire de N et de P, et nous avons montré que les régions, C-terminale de N (NTAIL) et N-terminale de P (PNT), sont prédites comme intrinsèquement désordonnées (RIDs). Les RIDs sont des régions fonctionnelles dépourvues de structures secondaires et tertiaires stables dans des conditions physiologiques. En utilisant des approches biochimiques et biophysiques, nous avons confirmé que NTAIL et PNT sont désordonnées. Elles conservent toutefois des structures secondaires transitoires qui pourraient correspondre à des éléments de reconnaissance moléculaire (ou MoREs) impliqués dans de transitions structurales en présence d'un partenaire
The Paramyxoviridae family includes many important human and animal pathogens, such as measles virus (MeV), a morbillivirus, and the emerging Nipah (NiV) and Hendra (HeV) viruses, members of the Henipavirus genus. Paramyxoviruses possess a negative-strand RNA genome that is encapsidated by the nucleoprotein (N) into a helical nucleocapsid. N interacts with the phosphoprotein (P), and this latter recruits the polymerase that ensures genome replication and transcription. My PhD project has mainly focused on the characterization of the N and P proteins and on the interactions between these two proteins from the three cognate viruses, namely NiV, HeV and MeV. While MeV has been extensively studied through the past years, structural and molecular information on Henipavirus N and P proteins were rather scarce. Using computational analyses, we deciphered the modular organization of Henipavirus N and P. Intrinsically disordered regions (IDRs) were predicted within these proteins, notably at the C-terminus of N (referred to as NTAIL), and at the N-terminus of P (referred to as PNT). IDRs are functional despite they lack of a well-defined 3-D structure under physiological conditions. Biochemical and biophysical approaches pointed out a mostly disordered state for both NTAIL and PNT, although they were shown to contain short-order prone segments (i.e. molecular recognition elements, MoREs). These latter are involved in partner recognition and in disorder-to-order transitions. The C-terminal domains of the P proteins (referred to as PXD) were found to bind to NTAIL and to induce an α-helical transition thereof
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Aurine, Noémie. "Etude de l'interaction entre le virus Nipah et son hôte réservoir la chauve-souris frugivore : établissement du modèle expérimental." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSEN019.

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Le virus Nipah (NiV) est un virus hautement pathogène responsable d’encéphalites et de syndromes respiratoires sévères chez l’humain. Les chauves-souris appartenant au genre Pteropus sont le réservoir naturel du NiV et ne développent pas de symptômes cliniques d’infection. Comprendre les relations entre l’hôte réservoir et le pathogène requiert la disponibilité de modèles pertinents pour l’étude des interactions. Les études portent à la fois sur le virus et son hôte. Ainsi, nous avons caractérisé phylogénétiquement la souche cambodgienne du NiV isolée de chauves-souris Pteropus et nous l’avons comparée avec les souches isolées chez l’homme. De plus, en absence du génome de référence pour l’espèce de chauve-souris Pteropus giganteus, nous avons séquencé et assemblé le génome de cette espèce, hôte réservoir de la souche NiV-Bangladesh, qui est en circulation actuellement. Enfin, afin d’obtenir des phénotypes cellulaires plus pertinents que des cellules immortalisées pour l’étude des interactions entre le NiV et les chauves-souris du genre Pteropus – les seules disponibles actuellement - nous avons utilisé la reprogrammation somatique sur des cellules primaires de chauve-souris Pteropus. Cette technique permet d’obtenir des cellules souches présentant la capacité d’autorenouvellement et de différenciation. En utilisant une combinaison originale de trois facteurs de transcription, nous avons généré les premières cellules reprogrammées de chauves-souris Pteropus exprimant des caractéristiques de cellules souches. Nous avons démontré que ces cellules sont très susceptibles à l’infection par le NiV mais incapables de produire de l’interféron et d’activer les cascades de signalisations antivirales en réponse à une stimulation avec de l’ARN double brin, contrairement aux cellules primaires. Le développement de ce modèle original ouvre de nouvelles perspectives pour l’étude des interactions entre l’hôte réservoir et le pathogène et pour l’identification de facteurs contrôlant la susceptibilité à l’infection par le NiV, et potentiellement par d’autres virus hébergés par des chauves-souris
Nipah virus (NiV) is a highly pathogenic virus that causes encephalitis and severe respiratory syndromes in humans. Pteropus bats are the reservoir of NiV and do not show any clinical symptoms. In order to understand the host reservoir - pathogen interactions, the relevant models are needed. Such studies focus on both the virus and its host. A phylogenetically characterization of the NiV Cambodian strain obtained from Pteropus bats was performed and this virus was compared with human ones. In addition, we sequenced and assembled the genome of Pteropus giganteus bat, the natural host of the NiV-Bangladesh strain, which is currently circulating. Up to date, most studies have used immortalized primary cells that are not natural target of the virus. In order to get reprogrammed stem cells, a somatic reprogramming approach was applied to various Pteropus primary cells. The reprogrammed cells are capable of self-renew and differente in different cell lineages. Using an original mix of transcription factors, we derived reprogrammed cells exhibiting stem cells features. We demonstrated the high susceptibly of these cells to henipavirus infections compared with the very low level of infection of the initial primary cells. Generated bat reprogrammed cells do not induce interferon production and signalisation in response to dsRNA. The development of this original model opens new perspectives on virus-host interaction studies, especially that of cellular anti-viral response by identifying factors controlling either susceptibility or restriction to the NiV infection, and possibly other viruses hosted by bats
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Hendra, Steve [Verfasser], and Carlos Ulises [Akademischer Betreuer] Moulines. "An analysis of intertheoretical connections in the interdisciplinary field : some cases of cognitive science / Steve Hendra ; Betreuer: Carlos Ulises Moulines." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1214593399/34.

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Magoffin, Danielle E. "Molecular analysis of J-virus and Beilong virus using reverse genetics." Curtin University of Technology. Division of Health Sciences, 2006. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=17641.

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The emergence of viruses in the family Paramyxoviridae, especially those such as Hendra virus and Nipah virus (NiV) that are zoonotic, highlighted the severity of disease that could be caused by infection with viruses belonging to this family. In addition to causing disease outbreaks, several newly discovered paramyxoviruses were found to have unique genetic features, which provoked renewed interest in the study of previously unclassified or uncharacterised viruses in this family. J-virus (JPV) was isolated from wild mice, in Queensland, Australia, in 1972, and has been suggested to be a natural respiratory pathogen of mice. Beilong virus (BeiPV), another paramyxovirus, was first isolated from human mesangial cells in Beijing, China, in 2003, and was subsequently detected in rat mesangial cells. Following initial characterisation, the genomes of JPV and BeiPV were found to contain two genes, SH and TM, not common to other paramyxoviruses, as well as an extended attachment protein gene. BeiPV has the largest genome in the family Paramyxoviridae, which is, in fact, larger than that of any other virus within the order Mononegavirales. The genetic material of paramyxoviruses is not amenable to manipulation via classical genetics; a reverse genetics approach was therefore employed to study the evolution and classification of JPV and BeiPV. Minireplicon systems utilising green fluorescent protein as a reporter were established for JPV, BeiPV and NiV, and were used to better assess the taxonomic status of JPV and BeiPV, and to determine the relationship between these viruses and henipaviruses, which also have exceptionally large genomes. These studies indicate that JPV and BeiPV are closely related and should be classified in the same genus and their replication and transcription machinery is different from that of the henipaviruses.
To gain an understanding of the biology of JPV and BeiPV, viral surface proteins from JPV were expressed and evaluated. Chimeric JPV virions containing recombinant surface proteins were generated and electron microscopy was used to determine the localisation of the proteins encoded by those JPV genes which are uncommon in other paramyxoviruses. Analysis of the attachment protein gene of JPV indicated that the virus was able to assemble an exceptionally large protein (156 kDa) into the virion structure, providing evidence in support of the hypothesis that JPV and BeiPV may represent an ancient lineage of viruses within the family Paramyxoviridae. In order to determine tissue tropism of JPV during experimental infection and to aid future work with a full-length JPV infectious clone, a real-time PCR assay for JPV was developed and assessed on tissues collected from mice infected with JPV. A multiplex microsphere assay for JPV and BeiPV was developed and used to analyse the seroprevalence of these viruses in Australian and Malaysian rodents. Although there is currently no evidence for disease caused by JPV or BeiPV, this does not preclude the emergence of a zoonotic rodent paramyxovirus related to these viruses. If this were to occur, the tools for virus detection and serological monitoring are now established.
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Kesuma, Hendra [Verfasser], Steffen [Akademischer Betreuer] Paul, Steffen [Gutachter] Paul, and Alberto [Gutachter] Garcia-Ortiz. "Low power design of a versatile analog mixed Signal sensor module / Hendra Kesuma ; Gutachter: Steffen Paul, Alberto Garcia-Ortiz ; Betreuer: Steffen Paul." Bremen : Staats- und Universitätsbibliothek Bremen, 2018. http://d-nb.info/1155300564/34.

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Pernet, Olivier. "Mise en évidence de l'entrée cellulaire du virus Nipah par macropinocytose : bases moléculaires et inhibition." Phd thesis, Ecole normale supérieure de lyon - ENS LYON, 2009. http://tel.archives-ouvertes.fr/tel-00448339.

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Les virus Nipah et Hendra sont deux Paramyxovirus émergents zoonotique apparu ces 15 dernières années en Asie du Sud-Est et en Australie. Ils sont responsables chez l'homme d'encéphalites dont le taux de mortalité peut dépasser les 90%. Il n'existe ni traitements, ni vaccins commercialisés. Ces virus sont donc classé P4. En étudiant la régulation négative de leur récepteur éphrineB2, j'ai pu mettre en évidence un mécanisme d'entrée endocytique pour le virus Nipah : la macropinocytose. Les Henipavirus sont les seuls Paramyxovirus connus dont on a pu démontré un tel mode d'entrée. En mimant le ligand naturel d'éphrineB2 (EphB4), les glycoprotéines virales G provoquent la rétractation des filopodes qui forment autour du virus des macropinosomes. De plus, l'entrée de ces virus peut-être bloquée in vitro par des inhibiteur de macropinocytose. Certain de ces inhibiteurs sont déjà utilisé en médecine humaine, ce qui ouvre la voie à un traitement peu onéreux contre ces dangereux pathogènes.
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Fouret, Julien. "Apport de la phylogénomique pour l’étude des interactions moléculaires entre Henipavirus et leurs réservoirs : les chauves-souris du genre Pteropus." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEN087.

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Les chauve-souris représentant un réservoir important pour de nombreux virus pathogènes pour l’homme, un ensemble d’études en évolution moléculaire converge vers l’évidence d’une forte pression de sélection au niveau de gènes impliqués dans l’immunité dans l’ordre Chiroptera. En particulier, les chauves-souris du genre Pteropus hébergent des virus de la famille Henipavirus: Nipah et Hendra. Ces virus sont responsables d'épidémies en Asie du sud-est, et bien qu'ayant un taux d'incidence bas, les maladies résultantes de l'infection ont un taux de létalité allant de 40% à 90% chez l'homme. L’infection atteint aussi la plupart des mammifères avec des symptômes clinique graves, (e.g. porc ou cheval : espèces d’intérêt agronomique). La particularité du genre Pteropus est de ne pas développer ces symptômes cliniques graves d’infection. Afin d'en identifier les bases génétiques, nous avons utilisé l'analyse de sélection positive sur l’ensemble du génome codant sans restreindre notre analyse aux gènes de l’immunité. Nous avons mis en place les outils informatiques innovants et nécessaires au déploiement de cette démarche. Ces analyses, reposent sur des séquences de références pour les génomes de différentes espèces, et en absence du génome de référence pour P. giganteus, nous l’avons préalablement séquencé et assemblé. Or, tous les gènes sous sélection ne sont pas forcément liés à notre phénotype d’intérêt mais possiblement à d’autres (e.g. capacité de vol). Nous avons mis en place un algorithme afin d’établir un lien fonctionnel potentiel entre ces gènes identifiés sous sélection positive et un phénotype d’intérêt
Bats represent a considerable reservoir for an extensive group of human pathogenic viruses. A number of molecular evolution studies points toward the evidence of a strong selection pressure in Chiroptera immune-related genes. Notably, Pteropus bats host viruses from Henipavirus genus: Nipah and Hendra. These viruses are responsible for epidemics in South-Est Asia, and, while the incidence is low, the resulting diseases are highly lethal, ranging between 40 to 90% in humans. Most of mammals are susceptible to the infection (including pigs and horses, animals valued in agronomy), and develop severe clinical symptoms. Specificity of Pteropus genus lies in the absence of clinical symptoms following the infection. In order to identify the genetic basis of this interesting phenomenon, we applied positive selection analysis to the entire coding genome, without bounding our analysis to immune-regulating genes. We have set breakthrough computational tools, without which our analysis would not have been possible. Reference sequences from genome of several species are the groundwork for our analysis. As P. giganteus reference genome has not yet been resolved, we sequenced and assembled it. However, not all genes under positive selection are necessarily linked to a phenotype of interest, but may be linked to other phenotypes (such as the flying ability). We have thus developed an algorithm to establish a possible functional link between the genes identified under positive selection and a phenotype of interest, which allows new perspectives in phylogenomic research
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Books on the topic "Hendra"

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Wisetrotomo, Suwarno. Hendra Gunawan, sang pelukis rakyat: Hendra Gunawan, the people's painter. Jakarta]: Agung Tobing, 2013.

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Jones, Geraint V. Band yr Hendra: Wmpa-wmpa! Llanrwst: Gwasg Carreg Gwalch, 2004.

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Parri, Ieuan. Teulu Hendra Doman: Deg o sgetsus. Capel Garmon: Gwasg Carreg Gwalch, 1985.

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Rahardja, Hendra. Cross examination: The case of Hendra Rahardja. Edited by Kaligis O. C, New South Wales. Supreme Court., and Indonesia Mahkamah Agung. Bandung: Alumni, 2000.

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Loemau, Alfons. Penegakan hukum oleh Polri: Studi kasus Hendra Rahardja. Jakarta: Restu Agung, 2005.

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Ekawaty, Kristianingsih, Siahaan Aron, and PTIK Press, eds. Penegakan hukum oleh Polri: Studi kasus Hendra Rahardja. Jakarta: Restu Agung, 2005.

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Wirata, Putu. Nyoman Gunarsa: Jalan panjang martir hak cipta & eksaminasi atas putusan bebas terdakwa Ir. Hendra Dinata. Malang: Bayumedia Pub., 2009.

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Oei, Hong Djien. The five maestros of modern Indonesian art: Affandi, S. Sudjojono, Hendra Gunawan, H. Widayat, Soedibio. Magelang, Jawa Tengah, Indonesia]: OHD Museum, 2012.

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Hamilton, Alan. A childhood: Stephen Hendry. London: Times Newspapers, 1991.

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Hendana. Leuven: Davidsfonds/Clauwaert, 1995.

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Book chapters on the topic "Hendra"

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Springfeld, Christoph. "Hendra-Virus." In Lexikon der Infektionskrankheiten des Menschen, 366–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-39026-8_443.

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Goh, Khean Jin, Kum Thong Wong, and Chong Tin Tan. "Nipah and Hendra Viruses Encephalitis." In New and Evolving Infections of the 21st Century, 279–93. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-32830-0_7.

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Field, Hume, Gary Crameri, Nina Yu-Hsin Kung, and Lin-Fa Wang. "Ecological Aspects of Hendra Virus." In Current Topics in Microbiology and Immunology, 11–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/82_2012_214.

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Georgiev, Vassil St. "Paramyxoviridae: Nipah Virus and Hendra Virus." In National Institute of Allergy and Infectious Diseases, NIH, 143–50. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-297-1_18.

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Bishop, Kimberly A., and Christopher C. Broder. "Hendra and Nipah Viruses: Lethal Zoonotic Paramyxoviruses." In Emerging Infections 8, 155–87. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555815592.ch9.

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Broder, C. C. "Passive Immunization and Active Vaccination against Hendra and Nipah Viruses." In Vaccines and Diagnostics for Transboundary Animal Diseases, 125–38. Basel: S. KARGER AG, 2013. http://dx.doi.org/10.1159/000171017.

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Basler, Christopher F. "Nipah and Hendra Virus Interactions with the Innate Immune System." In Current Topics in Microbiology and Immunology, 123–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/82_2012_209.

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Habchi, Johnny, Laurent Mamelli, and Sonia Longhi. "Structural Disorder within the Nucleoprotein and Phosphoprotein from Measles, Nipah, and Hendra Viruses." In Flexible Viruses, 47–94. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118135570.ch3.

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Halpin, Kim, and Paul Rota. "A Review of Hendra Virus and Nipah Virus Infections in Man and Other Animals." In Zoonoses - Infections Affecting Humans and Animals, 997–1012. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9457-2_40.

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Field, Hume. "The role of Grey-headed Flying-foxes in the ecology of Hendra virus, Menangle virus and Australian bat lyssavirus." In Managing the Grey-headed Flying-fox, 139–41. P.O. Box 20, Mosman NSW 2088, Australia: Royal Zoological Society of New South Wales, 2002. http://dx.doi.org/10.7882/fs.2002.047.

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Conference papers on the topic "Hendra"

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Sitanggang, Hendra Dhermawan, and Ummi Kalsum. "The Pattern of Snack And Beverage Concumption for Suku Anak Dalam (Sad) Children in The Trans Social Area of Nyogan Village, Muaro Jambi, Jambi Province." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.02.21.

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Background: Consumption of street food in school has an impact on children’s health, especially their nutritional status. Children in the Anak Dalam Tribe (SAD) are mostly malnourished and short. The remote indigenous community (Suku Anak Dalam) in Nyogan Village has undergone a social transition for 15 years since being granted permanent settlement by the Government. Many changes have occurred as well as consumption patterns. This study aims to determine the pattern of consumption of street food and beverages in schools for SAD children in Nyogan Village. Subjects and Method: This was a qualitative study with a phenomenological design conducted in Nyogan Village, Muaro Jambi Regency. Several information was selected for this study included: children, parents, community leaders or traditional leaders, school principals, teachers, neighbourhood leader, village heads, village midwives and public health center officer. The inclusion criteria were consumption pattern of food and drink snacks for SAD children at school. The data were collected by in-depth interview and analyzed using Miles and Hubberman’s model. Results: Children with SAD who go to elementary school in trans social areas in Nyogan Village like food and drink snacks. The most commonly consumed snack foods are sausages, sticky and grilled meatballs, thousand fried rice, candy, rice cake. At the same time, the most widely consumed snack drinks are present ice, juice jacket, glass tea, okky jelly drink, and ice cream. The reason is that only these types of food and beverages are available and cheap. SAD children in Nyogan Village rarely eat local snacks, such as fried sweet potatoes, that used to be consumed. There are concerns regarding the safety of snack foods and drinks suspected of having “chemical content” that is harmful to children health in these snacks. The cleanliness of the place of snacks and personal hygiene of food handlers are factors related to food and beverage snacks’ health. The Health Officer or public health center never conducts counseling on snack foods’ safety and is not regularly supervised. Conclusion: The consumption pattern of food and drink snacks for children with SAD in trans-social areas has changed. They consume snacks that are sold around the school. However, these foods and drinks are not guaranteed safety. Education and supervision are needed for food vendors or handlers in schools so that SAD children improve their health. Keywords: Consumption patterns, school snacks, children’s health, Suku Anak Dalam, qualitative Correspondence: Hendra Dhermawan Sitanggang. Program Studi Ilmu Kesehatan Masyarakat, Universitas Jambi. Jalan Tri Brata, Km 11 Kampus Unja Pondok Meja Mestong, Kab. Muaro Jambi. Email: hendrasitanggang@unja.ac.id. Mobile: 081361918000. DOI: https://doi.org/10.26911/the7thicph.02.21
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Wang, Shiyuan, Divyakant Agrawal, and Amr El Abbadi. "HengHa." In the 2010 ACM workshop. New York, New York, USA: ACM Press, 2010. http://dx.doi.org/10.1145/1866835.1866847.

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Deochake, Saurabh, Suresh Sarode, Shashank Kanth, Vidyasagar Potdar, Subhadip Chakraborty, and Debajyoti Mukhopadhyay. "HENRI." In the CUBE International Information Technology Conference. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2381716.2381840.

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Waintraub, Sarah. "Being henry." In SIGGRAPH '19: Special Interest Group on Computer Graphics and Interactive Techniques Conference. New York, NY, USA: ACM, 2019. http://dx.doi.org/10.1145/3306449.3328802.

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Ugorowski, P., S. Bellinger, L. Crow, C. Henderson, W. L. Dunn, W. J. McNeil, R. D. Taylor, and D. S. McGregor. "Characterization of the High-Efficiency Neutron Detector Array (HENDA)." In 2008 IEEE Nuclear Science Symposium and Medical Imaging conference (2008 NSS/MIC). IEEE, 2008. http://dx.doi.org/10.1109/nssmic.2008.4774760.

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Hager, Willi H., and Corrado Gisonni. "Henry Bazin: Hydraulician." In Symposium to Honor Henry Philibert Caspard Darcy. Reston, VA: American Society of Civil Engineers, 2003. http://dx.doi.org/10.1061/40683(2003)9.

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Emel'yanov, I. K. "The image of Henry V in Shakespeare's play Henry V." In Scientific dialogue: Questions of philosophy, sociology, history, political science. ЦНК МОАН, 2019. http://dx.doi.org/10.18411/spc-01-11-2019-02.

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Bennaceur, Said, Lyes Bennamoun, Antonio Mulet, Belkacem Draoui, and Juan A. Cárcel. "Effect of ultrasound on drying kinetics of El Henna leaves (Lawsonia inermis)." In 21st International Drying Symposium. Valencia: Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/ids2018.2018.7530.

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In this work the influence of some process variable on drying rate of henna leaves was studied. For this reason, henna leaves were dried (1 m/s) with and without ultrasound application at three temperatures, 40, 50 and 60 °C. As can be expected, the higher the temperature the faster the drying process. Ultrasound application increase drying rate at every temperature tested. Drying kinetics were modeled by using different experimental models. Weibull model provided the best fit for henna leaves drying kinetics. Keywords:Ultrasonic; Weibull model; henna leave;, temperature.
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Chen, Chong, Jun Zou, Dezheng Xu, Qin Zeng, and Minghuang Wang. "The Testing and Application of Continuous-Energy Neutron Cross Section Library HENDL-ADS/MC." In 2013 21st International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icone21-16514.

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A point-wise cross-section data library HENDL-ADS/MC (Hybrid Evaluated Nuclear Data Library) has been produced by FDS team to do the nuclear analysis for the ADS system. The HENDL-ADS/MC library contained 408 nuclide cross-section files including actinides, fission products and structural materials for neutron energy up to 150 MeV. The nuclear library also contained several sub-libraries with different temperatures. A series of neutron integral experiments and critical safety benchmarks have been performed to test the availability and reliability of the HENDL-ADS/MC data library. To validate and qualify the reliability of the high neutron energy cross section for HENDL-ADS/MC library further, a series of high neutron shielding experiments have been performed using MCNP. The testing results indicated the accuracy and reliability of HENDL-ADS/MC library.
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Zhijiang Fang, Ronghong Jin, and Junping Geng. "Reconfigurable hendeca-band antenna for wireless communication." In 2009 IEEE International Workshop on Antenna Technology "Small Antennas and Novel Metamaterials" (iWAT). IEEE, 2009. http://dx.doi.org/10.1109/iwat.2009.4906907.

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Reports on the topic "Hendra"

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Fusco, Deborah L. The Role of the Hendra Virus and Nipah Virus Attachment Glycoproteins in Receptor Binding and Antibody Neutralization. Fort Belvoir, VA: Defense Technical Information Center, January 2014. http://dx.doi.org/10.21236/ad1012829.

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Swetz, Frank J. Mathematical Treasure:Arithmetica Logarithmicaof Henry Briggs. Washington, DC: The MAA Mathematical Sciences Digital Library, March 2013. http://dx.doi.org/10.4169/loci003959.

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Henry, Charles. SafePort Proposal - Henry Laboratory 2010. Fort Belvoir, VA: Defense Technical Information Center, November 2013. http://dx.doi.org/10.21236/ada600049.

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Raff, Daniel M. G., and Lawrence Summers. Did Henry Ford Pay Efficiency Wages? Cambridge, MA: National Bureau of Economic Research, December 1986. http://dx.doi.org/10.3386/w2101.

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Dixon, Kafi, Jinghua Chen, and Steve Shannon. Henry County Affordable Housing Evaluation and Implementation. University of Iowa, May 2001. http://dx.doi.org/10.17077/ci55-duim.

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Schmidt, Barbara. Engineering soils map of Henry County, Indiana. West Lafayette, IN: Purdue University, 1990. http://dx.doi.org/10.5703/1288284313437.

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Amble, Nina, and Elisabeth Gjerberg. Hjerte, hode, hender : et refleksjonsverktøy for mestring i pleie- og omsorgstjenesten. Oslo: Arbeidsforskningsinstituttet og Sosial- og helsedirektoratet (distributør), 2007. http://dx.doi.org/10.7577/afi/fou/2007/1.

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Henderson, J. R. Geology, McBeth Fiord-Cape Henry Kater, District of Franklin. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1985. http://dx.doi.org/10.4095/120467.

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Buiter, Willem. Debt Neutrality, Professor Vickrey and Henry George's "Single Tax". Cambridge, MA: National Bureau of Economic Research, August 1988. http://dx.doi.org/10.3386/w2673.

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Jones, Patricia. Environmental Programs at Los Alamos National Laboratory - Paul Henry. Office of Scientific and Technical Information (OSTI), October 2012. http://dx.doi.org/10.2172/1053546.

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