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Dissertations / Theses on the topic 'Hepatitis treatment'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Williams, Stephen John. "Chronic hepatitis B virus infection : prevention and treatment." Thesis, The University of Sydney, 1989. https://hdl.handle.net/2123/26390.

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Hepatitis B virus (HBV) infection is an increasing public health problem in Australia particularly in certain 'high-risk' subgroups of the population. In order to establish cost-effective screening and vaccination programs directed towards the control and possible eradication of HBV infection, accurate information is needed about the modes of spread and the numbers of "at risk" individuals in particular community subgroups. In addition, treatment strategies must be developed for established HBV carriers since at least 35% of such individuals will die directly related to complications of the di

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2

Carlsson, Tony. "Hepatitis C virus kinetics during antiviral treatment /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-588-3/.

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3

Bangera, Sudhakar Sheena. "Review of hepatitis B treatment : in practice and in development /." Thesis, Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B24873147.

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4

Sangfelt, Per. "Prevention and treatment of hepatitis B virus infection /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-301-9/.

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5

Watson, Henry G. "Viral hepatitis as a complication of haemophilia treatment." Thesis, University of Aberdeen, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337399.

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Post transfusion hepatitis is seen in all haemophiliacs treated with non-virus inactivated (NVI) concentrates. First generation anti-HCV ELISA produced false negative results in 10/78, with four individuals ELISA negative, HCV RNA positive. Using second generation assays incorporating c22, C1-4 and c33c peptides, HCV infection was demonstrated in all recipients of NVI concentrates and 0/7 PUPS treated with heat treated concentrates. Phylogenetic analysis of HCV sequences outlined the demographic of HCV infection in Edinburgh and suggested that recent post-transfusion HCV infection is due to tr

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6

Seto, Wai-kay Walter, and 司徒偉基. "Virologic and serologic kinetics in the natural history and treatment of chronic hepatitis B." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48671071.

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This thesis investigated how virologic and serologic kinetics of the hepatitis B virus (HBV) could influence the natural history and treatment of chronic hepatitis B (CHB). Virologic kinetics were described in the first five studies, with serologic kinetics being described in the next five. The first study delineated the HBV DNA profiles of 1,400 treatment-naive Asian CHB patients. Increasing viremia was noted with increasing age, highlighting the large therapeutic demand in Asian patients with hepatitis B e antigen (HBeAg)-negative CHB. The second study analyzed the association between vira

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7

Weegink, Christine Joanne. "Hepatitis C infection the quest for new treatment strategies /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2004. http://dare.uva.nl/document/74129.

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8

Lewis, Heather Ilona. "Improving ascertainment and treatment rates of chronic viral hepatitis." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/30632.

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Introduction and aims: In the United Kingdom hepatitis B virus (HBV) and hepatitis C virus (HCV) disproportionately affect migrants and people who inject drugs (PWID). Ascertainment rates of HBV and HCV are 10-40% and screening is recommended in at risk groups. Treatment uptake for HCV in PWID is low at 2-18%, and the most effective way to increase uptake is not known. This research aims to evaluate methods to address the low ascertainment and treatment rates of HBV and HCV in these populations. Methods: A pilot observational cohort study of screening for chronic viral hepatitis in primary car

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9

Yuen, King-tai, and 袁敬弟. "A study of pharmacogenomics for therapeutic and prognostic guidance towards hepatitis C virus (HCV) for patients co-infected with HIV." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193555.

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The cost effectiveness of using novel HCV treatment option, telaprevir and boceprevir, should depend on patients’ respond to conventional PEG-INFα and ribavirin therapy. The study of pharmacogenomics, interleukin-28B (IL-28B) polymorphisms, accompanied with the information of HCV genotypes are suggested to have the strongest predictive value of treatment outcomes and prognosis of disease in individuals infected with HCV who are undergoing conventional PEG-INFα and ribavirin therapy. It is extremely valuable in HCV/HIV co-infected patients as these groups of patients require a complex treatment

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10

Christou, Marie-Grace. "Conditionally activated therapeutics for the treatment of hepatitis C." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/26609.

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Hepatitis C virus (HCV) is the etiologic agent responsible for the majority of cases of non-A, non-B hepatitis. It is estimated that 2% of the world's population is infected with hepatitis C with roughly 75% of infections progressing into a chronic state. Current interferon therapy is largely ineffective against chronic Hepatitis C due to the induction of interferon-resistance by HCV. The underlying mechanisms for resistance to interferon therapy have been widely studied and documented and as is the case in interferon resistant malignancies, there is some evidence that HCV infected cells are m

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11

Smith, Jennifer. "Viral diversity and dynamics of hepatitis C virus." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.559853.

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Complex patterns of HCV infection are increasingly reported, particularly in highly exposed individuals, with multiple and variable subtype profiles seen in many chronic patients. This study aims to address some of the questions arising from this increasingly diverse and dynamic picture, both within hosts and at a population level. In Chapter 2 I find evidence for a highly dynamic infection profile in acute HCV, both in terms of viral load and the dominant subtype. I extrapolate these observations from individual patients to formulate a model of HCV transmission across a high-risk population i

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12

Veldt, Bartholomeus Johannes. "Long-term clinical outcome of treatment for chronic hepatitis C." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/12624.

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13

Prysyazhnyuk, V. P. "Сomplex treatment with quercetin inclusion in chronic nonviral hepatitis patients". Thesis, БДМУ, 2022. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19576.

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14

Whiteley, David James. "Recontextualising the lived experience of hepatitis C and its treatment." Thesis, Edinburgh Napier University, 2016. http://researchrepository.napier.ac.uk/Output/979740.

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BACKGROUND: Rapid advances in the treatment of the hepatitis C virus (HCV) have been witnessed in clinical practice over the last five years. Pharmacological developments have ended the reliance on the drug interferon-α as a component of successful therapy, heralding the dawn of a new era in the fight against the disease. How this new era is being understood and experienced by those individuals living with the virus is currently unknown. METHODS: A purposive sample of 20 individuals participated in face-to-face semi-structured interviews exploring their experience of living with HCV. Eight of

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15

Fetherston, James Andrew. "Hepatitis C, Treatment and Drug Use in Australian Prison Settings." Thesis, Curtin University, 2021. http://hdl.handle.net/20.500.11937/83447.

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This thesis examined issues surrounding the hepatitis C virus (HCV), its treatment, and injecting drug use as the principal risk factor for infections in Australian prison environments. Quantitative and qualitative data was collected from both former and current prisoners to explore knowledge and attitudes towards treatment. Additional data concerning drug use was collected via existing national surveys. Epidemic modelling was used to determine the potential of increased prisoner engagement in treatment.

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16

Laestadius, Hanna, and Berfin Güven. "Hur patienter med hepatit B och hepatit C upplever bemötandet av omvårdnadspersonal." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397661.

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Background: In 2019, hepatitis is seen as one of the deadliest virus infections in the world and is seen as a global health problem. Hepatitis is a DNA-virus that can lead to chronic hepatitis and liver cirrhosis. Both hepatitis B and C are blood infections which means that they are transmitted through contact with damaged skin, mucus membrane or the eyes. Aim: The aim of this study was to describe how patients with hepatitis B and C experience the treatment from healthcare professionals. Method: The method used in this study was a review of literature research. The study was conducted through

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17

Lau, Ka-kit George, and 廖家傑. "Hepatitis B infection and hematopoietic stem cell transplantation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31981756.

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18

Yuen, Man-fung, and 袁孟峰. "Chronic hepatitis B virus infection in the Chinese: natural history, sequelae, treatment and prevention." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B2333177X.

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19

Fialho, Renata. "Neuropsychiatric manifestations of hepatitis C treatment in HIV/HCV co-infection." Thesis, University of Sussex, 2017. http://sro.sussex.ac.uk/id/eprint/71260/.

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Hepatitis C (HCV) infection is associated with high rates of mortality and morbidity. Interferon alpha based treatment for HCV offers a good rate of viral clearance, however the associated neuropsychiatric side effects increase the risk of treatment interruption and disease progression. The HIV/HCV coinfection is of particular interest due to association with higher rates of HCV treatment side effects and earlier treatment discontinuation when compared with HCV mono-infection. Therefore, the aim of the thesis was to further explore the effect of coinfection on mood and cognition and how HCV in

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20

Sgorbini, Myra. "Living with Hepatitis C and treatment a phenomenological study of the experience of patients and their partners /." View thesis, 2007. http://handle.uws.edu.au:8081/1959.7/19046.

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Thesis (M.Sc. (Hons.)) -- University of Western Sydney, 2007.<br>A thesis submitted towards the degree of Master of Nursing (Honours) in the University of Western Sydney, College of Health and Science, School of Nursing. Includes bibliographical references.

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21

Cornacini, Milena Costa Menezes [UNESP]. "Efeito do uso do cogumelo Agaricus brasiliensis no estado nutricional, na frequência e intensidade dos efeitos adversos da terapia medicamentosa e na resposta bioquímica hepática em indivíduos com hepatite crônica pelo vírus C: estudo prospectivo, randomizado, duplo cego, placebo controlado." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/102636.

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Made available in DSpace on 2014-06-11T19:32:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-07-23Bitstream added on 2014-06-13T18:43:14Z : No. of bitstreams: 1 cornacini_mcm_dr_botfm.pdf: 480494 bytes, checksum: b0bc2df21341fdbd2b117efc1905a4b8 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Diversos estudos, indicam que o cogumelo Agaricus brasiliensis é benéfico em várias condições clínicas, como na hepatite C. Várias espécies de cogumelos comestíveis têm sido exploradas quanto ao seu potencial medicinal e muitos pacientes passam a buscar a soluç

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Sgorbini, Myra. "Living with Hepatitis C and treatment : a phenomenological study of the experience of patients and their partners." Thesis, View thesis, 2007. http://handle.uws.edu.au:8081/1959.7/19046.

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Among the estimated 210,000 Australians living with the hepatitis C virus, over 80% will go on to live with chronic hepatitis C and its debilitating effects. Patients with chronic hepatitis C who have active inflammatory changes on liver biopsy may undergo combination therapy with interferon and ribavirin. Adverse effects of combination therapy can be variable in their nature, intensity and severity. They may be mild, reversible, moderate, or serious and life threatening. For some patients the adverse effects are so severe that it places enormous stress on partner relationships. Through a phen

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23

Lindahl, Karin. "Ribavirin - dose and concentration in treatment of chronic hepatitis C infected patients /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-348-5/.

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24

Gill, Upkar S. "Harnessing the immune response to optimise treatment strategies in chronic hepatitis B." Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/53580.

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Chronic Hepatitis B (CHB) related cirrhosis and hepatocellular carcinoma (HCC) account for more than 750,000 deaths per year. Current therapies for CHB are limited in achieving HBsAg decline/loss and thus there remains a pressing need for curative treatment strategies. Although, Pegylated Interferon-α (Peg-IFNα) may be used, the majority of patients progress to nucleos(t)ide analogue (NUC) therapy due to treatment failure. Peg-IFNα and NUCs used in isolation act differentially on the immune response; Peg-IFNα induces NK cell activation and NUC therapy may partially restore T cell function. NK

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25

Carracedo, Rodriguez Andrea. "Mathematical Models of Hepatitis B Virus Dynamics during Antiviral Therapy." Thesis, Virginia Tech, 2016. http://hdl.handle.net/10919/70759.

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Antiviral therapy for patients infected with hepatitis B virus is only partially efficient. The field is in high demand for understanding the connections between the virus, immune responses, short-term and long-term drug efficacy and the overall health of the liver. A mathematical model was introduced in 2009 to help elucidate the host-virus dynamics after the start of therapy. The model allows the study of complicated viral patterns observed in HBV patients. In our research, we will analyze this model to determine the biological markers (e.g. liver proliferation, immune responses, and drug ef

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NASCIMENTO, Wheverton Ricardo Correia do. "Estudo a ação imunorregulatória do extrato solúvel de Ascaris Suum sobre a injúria hepática experimental mediada por células imunes." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/18506.

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Submitted by Caroline Falcao (caroline.rfalcao@ufpe.br) on 2017-04-06T17:10:41Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) 2012-dissertação-WhevertonRicardoCorreiaNascimento.pdf: 4035736 bytes, checksum: f33cf235cb56b67d16c3e819dbebb2a1 (MD5)<br>Made available in DSpace on 2017-04-06T17:10:41Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) 2012-dissertação-WhevertonRicardoCorreiaNascimento.pdf: 4035736 bytes, checksum: f33cf235cb56b67d16c3e819dbebb2a1 (MD5) Previous issue date: 2012-03-

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TEIXEIRA, Fábio Gomes. "AVALIAÇÃO DA EFETIVIDADE DO PROGRAMA DE TRATAMENTO DA HEPATITE C CRÔNICA EM USUÁRIOS DA FARMÁCIA ESTADUAL DE MEDICAMENTOS EXCEPCIONAIS DO MARANHÃO (FEME)." Universidade Federal do Maranhão, 2011. https://tedebc.ufma.br/jspui/handle/tede/tede/1989.

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Submitted by Maria Aparecida (cidazen@gmail.com) on 2017-11-13T14:21:15Z No. of bitstreams: 1 Fábio Gomes Teixeira.pdf: 415617 bytes, checksum: 372db933a02a007f513b9a2d77a17362 (MD5)<br>Made available in DSpace on 2017-11-13T14:21:15Z (GMT). No. of bitstreams: 1 Fábio Gomes Teixeira.pdf: 415617 bytes, checksum: 372db933a02a007f513b9a2d77a17362 (MD5) Previous issue date: 2011-10-18<br>Cohort study using retrospective data to evaluate the effectiveness of the treatment program for chronic hepatitis C in users of Farmácia Estadual de Medicamentos Excepcionais do Maranhão (FEME) to determine t

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Thorburn, Douglas. "Hepatitis C infection in the west of Scotland : epidemiology, treatment and disease progression." Thesis, University of Glasgow, 2001. http://theses.gla.ac.uk/5374/.

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After the discovery of and development of diagnostic tests for hepatitis A and B it became apparent that a parenterally transmissible agent was responsible for cases of non-A non-B hepatitis. It was not until 1989, a further fifteen years later, that the agent responsible for most cases, the hepatitis C virus (HCV), was identified. This virus was initially thought to cause a mild self-limiting hepatitis. With the introduction of serological screening tests for HCV, it was soon apparent that it caused a chronic asymptomatic hepatitis which could be accompanied by significant fibrosis and someti

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Ranson, Carly Anne. "CLINICAL FACTORS ASSOCIATED WITH HEPATITIS C TREATMENT SELECTION IN A VETERANS AFFAIRS POPULATION." Scholarly Commons, 2017. https://scholarlycommons.pacific.edu/uop_etds/2986.

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Background: Hepatitis C virus is currently the most common chronic blood borne pathogen in the United States, with only half of those infected aware of their condition. The cost for treatment is higher with Harvoni® (ledipasvir/sofosbuvir) than Viekira Pak® (ombitasvir/paritaprevir/ritonavir and dasabuvir). With finite resources available to treat patients, it is important to understand which clinical factors may influence treatment selection decisions. Methods: The study is a 12-month medical record review within the Veterans Affairs (VA) system to evaluate significant relationships betwe

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Bourdin, Claire. "Antiviral drug design, synthesis and biological evaluation for treatment of Hepatitis C virus." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/45541/.

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Hepatitis C virus is an infectious disease affecting millions of people worldwide and causing chronic liver disease. The current standard of care is not only long but causes numerous side effects. Due to incomplete virological response and poor tolerability, only 50% of the patients are cured, with variability by genotype. Despite the development of non-enzymatic viral protein inhibitors, new therapies target mainly enzymes responsible for viral replication or translation. Being commonly used for antiviral and anticancer therapy, nucleosides analogues have played an important role as anti-HCV

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31

Rashidi, Amineh. "Treatment of hepatitis C in injecting drug users in the Perth metropolitan area." Thesis, Curtin University, 2016. http://hdl.handle.net/20.500.11937/2207.

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This study used a sequential exploratory mixed methods research to develop a better understanding of the context of treatment intentions of IDUs living with HCV in Perth Metropolitan area. Sixty three percent of participants expressed that they had intention to uptake HCV treatment. Characteristics of treatment, stigma and lack of support emerged as factors influencing intention to uptake HCV treatment. The findings will help to make the world a better place by scaling up HCV treatment for IDUs in the community setting.

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Poon, Hung-wai Philip. "Hepatitis B carrier state and its implications in the dental treatment of handicapped patients." Hong Kong : Faculty of Dentistry, The University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19902207.

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33

Lukashevych, I. V. "Dynamics of indicators antioxidant protection in patients with chronic hepatitis during the comprehensive treatment with inclusion “Heptral” belongs to disease with chronic hepatitis." Thesis, БДМУ, 2022. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19572.

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Kubota, Kaori. "Analise do tratamento das hepatites virais B e C nos usuários atendidos pelo Sistema Único de Saúde no estado do Amapá." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-19012011-130832/.

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As hepatites são as causas mais comuns de cirrose hepática e carcinoma hepatocelular (HCC) no mundo, sendo as infecções por Vírus da Hepatite B (HBV) e Vírus da Hepatite C (HCV) consideradas aquelas de maior importância como problemas de saúde pública, devido ao grande número de indivíduos atingidos (cerca de 350 milhões com hepatite B crônica e 170 milhões com HCV). No Brasil, avaliações realizadas nas últimas décadas sugerem que a endemicidade da hepatite B na região amazônica não tem decaído, com o agravante da precariedade do acesso aos cuidados de saúde nessa região. Assim, este estudo te

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35

Delahooke, Toby Edward Stuart. "The natural history and treatment of hepatitis C in the South-East of Scotland." Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/27891.

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Background: Since the discovery of Hepatitis C there have been studies of the natural history of the infection. The outcome is dependent on whether the research is performed in the community or in hospital and where the patients are drawn from. Scotland is a country with a low prevalence of Hepatitis C infection but Edinburgh has a large intravenous drug using population in whom the prevalence is high. The Royal Infirmary of Edinburgh is the main tertiary centre for the assessment and treatment of these patients. Aim: Describe the characteristics of those patients that have ongoing Hepatitis C

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36

Zaman, Muhammad Haidar. "Improvement in Hepatitis “C” viral infection with advanced antiviral therapy,treatment – a meta-analysis." Thesis, Södertörns högskola, Institutionen för naturvetenskap, miljö och teknik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-27817.

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Background: Hepatitis is the inflammation of liver and there are many reasons of hepatitis. Among these reasons the viral hepatitis due to hepatitis B virus (HBV) and hepatitis C Virus (HCV) are the common hepatic infections and the major causes of liver cancer and liver cirrhosis in the world especially in Asia and Medal east. HBV and HCV infections are having very high mortality ratio in Europe and every year millions of people become infected and die due to HBV or HCV in Europe and Worldwide. That’s why viral hepatitis needs a serious consideration and perfect treatment. Objective: Objectiv

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Joshi, Deepak. "Recurrent hepatitis C virus infection post liver transplantation : predictors of fibrosis and treatment response." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/recurrent-hepatitis-c-virus-infection-post-liver-transplantation(e916f7ed-9931-4f3b-8555-4833f90a3586).html.

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Infection with chronic hepatitis C virus (HCV) is the leading indication for liver transplantation. Recurrence, however of HCV is universal after liver transplantation and subsequent fibrosis rates after transplantation are accelerated leading to significant morbidity and mortality. In addition, treatment of recurrent HCV after transplantation with pegylated-interferon (PEG) and ribavirin (RBV) are poorly tolerated and are associated with inferior treatment outcomes. The ability to therefore understand the mechanisms that relate to disease recurrence and therefore develop markers of fast fibro

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Mouton, Marlize National Centre in HIV Social Research Faculty of Arts &amp Social Sciences UNSW. ""More than a liver" - the role of the social work practitioner in hepatitis C treatment centres." Publisher:University of New South Wales. National Centre in HIV Social Research, 2008. http://handle.unsw.edu.au/1959.4/41466.

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Hepatitis C is a fast growing infectious disease in Australia and is often associated with related psycho-social and mental health problems. The conventional treatment process for hepatitis C is challenging due to a number of reasons. This study explored social workers perceptions of the contribution of their role in hepatitis C treatment centres in relation to the treatment experience of patients. The roles that social workers fulfill, their contribution to the multidisciplinary team and towards a culturally competent service, were explored. Furthermore the knowledge, skills and values r

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Machado, Danusa de Almeida [UNESP]. "Qualidade de vida e morbidade psicológica de pacientes portadores de hepatite C em tratamento com interferon peguilado e ribavirina." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/98430.

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Made available in DSpace on 2014-06-11T19:29:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-08-18Bitstream added on 2014-06-13T20:59:47Z : No. of bitstreams: 1 machado_da_me_botfm.pdf: 1394729 bytes, checksum: cf122227c1c036a13854129f11cd25e1 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O presente estudo teve por objetivo descrever características sóciodemográficas, psicossociais, clínicas, índices de qualidade de vida, ocorrência de transtorno mental comum, de sintomas depressivos de pacientes portadores de Hepatite C crônica, em tratamento no Ambulat

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Astell-Burt, Thomas. "Geographies of hepatitis C : exploring the extent to which geographic accessibility to healthcare influences outcomes amongst individuals infected with Hepatitis C in NHS Tayside, Scotland." Thesis, University of St Andrews, 2010. http://hdl.handle.net/10023/2135.

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Millions of people are infected with the Hepatitis C Virus (HCV) worldwide. In the UK, many individuals continue to live with undiagnosed HCV infection and are increasingly at risk of developing life-threatening cirrhosis and liver cancer. Of those that are diagnosed, only some are referred to an HCV specialist centre where vital treatment could cure their infection. Of those that are referred, only a proportion have actually attended and stayed in follow-up with a specialist centre. Geographic access to healthcare may be an important factor in these trends, but has so far received little atte

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Ali, Rahma, Sylvia Trinh, Jared Turley, Dan Malone, and Marcella Honkonen. "Comparing the Efficacy of Direct Acting Antiviral Agents for the Treatment of Hepatitis C Virus Genotype 1." The University of Arizona, 2016. http://hdl.handle.net/10150/613948.

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Class of 2016 Abstract<br>Objectives: To compare the efficacy of direct acting antiviral agents for the treatment of hepatitis C virus genotype 1. Our primary null hypothesis is there will be no significant difference in efficacy among the treatment regimens for hepatitis C virus, genotype 1. Methods: This meta-analysis study will use published literature identified from Embase and PubMed for phase II or III clinical trials evaluating direct acting antiviral drug regimens to treat adults with hepatitis C virus (HCV) genotype 1 infection. The primary outcome of interest is SVR at 12 weeks afte

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Baloch, Baby Kanwal. "Development of a targeted drug delivery system for the treatment of hepatitis C virus infection." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/14295/.

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Background: Hepatitis C virus infection affects more than 170 million people worldwide and is frequently associated with chronic liver disease and hepatocellular carcinoma. No protective vaccine is yet available and the current standard of care, consisting of pegylated interferon alpha and ribavirin, has limited efficacy. Ribavirin is a key component of any effective anti-HCV regimen. However, accumulation of ribavirin in the red cell compartment not only reduces drug efficacy as a result of diversion to extra-hepatic sites but also produces haemolytic anaemia which can lead to dose reduction

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Serag, Hani. "Barriers to accessibility to antiviral treatment for patients with Chronic Viral Hepatitis C in Egypt." University of Western Cape, 2014. http://hdl.handle.net/11394/6070.

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Magister Public Health - MPH (Public Health)<br>Egypt has the highest burden of Hepatitis C Viral infection (HCV) in the world with 10% between 15- 60 years old having HCV antibodies and 7% having chronic HCV infection. HCV is more concentrated among rural, aged, less educated, and poor population groups in addition to patients who require frequent blood transfusion or on renal dialysis, and injection drug users. Despite advancement in antiviral treatments with higher than 90% sustained virologic response (efficacy), access remains limited. The government strategy tied expanding the acce

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Coxe, Paul Cameron. "An Examination of Hepatitis A Virus on Working Surfaces in a Waste Water Treatment Plant." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533208035412584.

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Barcos, Iara Pinheiro. "Análise da prevalência e de fatores de risco para as hepatites virais crônicas B e C em idosos residentes no município de Botucatu-SP /." Botucatu, 2013. http://hdl.handle.net/11449/108650.

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Orientador: Giovanni Faria Silva<br>Banca: Cássio Vieira de Oliveira<br>Banca: Neiva Sellan Lopes Gonçales<br>Resumo: A Organização Mundial de Saúde (OMS) define como idoso todo indivíduo com mais de 60 anos de idade. Atualmente no Brasil os idosos são aproximadamente 15 milhões de pessoas e apesar de viverem mais, apresentam maiores condições crônicas devido ao declínio da maioria das funções orgânicas, inclusive do sistema imunológico, aumentando a susceptibilidade e a maior incidência de doenças infecciosas. As hepatites virais tem distribuição mundial e são doenças infecciosas que apresent

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Sinclair, Michael. "A qualitative exploration of coping and adhering with hepatitis C treatment amongst a cohort of gay men in London co-infected with HIV and hepatitis C." Thesis, University of Essex, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435559.

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Silva, Ágabo Macêdo da Costa e. "Genotipagem do vírus da hepatite C e avaliação da resposta ao tratamento em Goiânia-Goiás, com ênfase no polimorfismo relacionado ao gene IL28B." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/3710.

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Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2014-11-27T19:29:54Z No. of bitstreams: 2 Dissertação - Ágabo Macêdo da Costa e Silva- 2014.pdf: 1890977 bytes, checksum: 8a4d7bcee9ab084556c93c3c72e6a9f8 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Cláudia Bueno (claudiamoura18@gmail.com) on 2014-12-01T14:46:26Z (GMT) No. of bitstreams: 2 Dissertação - Ágabo Macêdo da Costa e Silva- 2014.pdf: 1890977 bytes, checksum: 8a4d7bcee9ab084556c93c3c72e6a9f8 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a77

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Ouno, Daniela Donha. "Hepatite autoimune tipo 1 em crianças: fatores laboratoriais associados com a resposta histológica e evolução da doença." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-10102012-102213/.

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INTRODUÇÃO: A pesquisa de fatores que possam reconhecer precocemente quais serão os pacientes portadores de HAI com boa evolução ou aqueles que serão resistentes ao tratamento, levaria a um melhor planejamento da terapia. OBJETIVOS: Determinar se fatores laboratoriais pré-tratamento, e o tempo necessário para atingir remissão clínico-laboratorial são preditivos de remissão histológica ou melhora do grau arquitetural na HAI tipo1 em crianças. MÉTODOS: Estudo retrospectivo com 50 crianças portadoras de hepatite autoimune tipo 1 acompanhadas na Unidade de Hepatologia Pediátrica do Instituto da Cr

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Cornacini, Milena Costa Menezes. "Efeito do uso do cogumelo Agaricus brasiliensis no estado nutricional, na frequência e intensidade dos efeitos adversos da terapia medicamentosa e na resposta bioquímica hepática em indivíduos com hepatite crônica pelo vírus C : estudo prospectivo, randomizado, duplo cego, placebo controlado /." Botucatu : [s.n.], 2009. http://hdl.handle.net/11449/102636.

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Resumo: Diversos estudos, indicam que o cogumelo Agaricus brasiliensis é benéfico em várias condições clínicas, como na hepatite C. Várias espécies de cogumelos comestíveis têm sido exploradas quanto ao seu potencial medicinal e muitos pacientes passam a buscar a solução para suas patologias nas terapias complementares. Avaliar os efeitos da suplementação do Agaricus brasiliensis sobre o estado nutricional, a frequência e a intensidade dos efeitos adversos da terapia antiviral e a resposta bioquímica hepática em indivíduos com hepatite C em tratamento com Interferon peguilado e Ribavirina. Foi

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Xiao, Fei. "Hepatitis C virus entry and cell-cell transmission : implication for viral life cycle and antiviral treatment." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAJ124/document.

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Le virus de l'hépatite C (HCV) représente un problème de santé publique à l'échelle mondiale. Les thérapies actuelles ne permettent pas de guérir tous les patients infectés par le HCV et certains antiviraux ont des effets secondaires importants. Dans la première partie de ma thèse, nous avons identifié des combinaisons d'antiviraux à action directe (DAA) et d'inhibiteurs d'entrée caractérisés par un effet synergique dans la prévention et le traitement du HCV dans des modèles de culture cellulaire et les souris uPA-SCID avec un foie chimérique. Ceci représente une nouvelle stratégies de lutte c

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