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1

Taylor, K. J. W. "Hepatobiliary system." Ultrasound in Medicine & Biology 26 (May 2000): S71—S72. http://dx.doi.org/10.1016/s0301-5629(00)00169-1.

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2

GONZALEZ-BROWN, VERONICA, and HEATHER A. FREY. "The Hepatobiliary System." Clinical Obstetrics and Gynecology 63, no. 1 (March 2020): 122–33. http://dx.doi.org/10.1097/grf.0000000000000504.

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3

Hynes, Daniel, Christina Duffin, and Tara Catanzano. "Infections of the Hepatobiliary System." Seminars in Ultrasound, CT and MRI 41, no. 1 (February 2020): 46–62. http://dx.doi.org/10.1053/j.sult.2019.10.003.

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4

Farrell, Frank J., and Emmet B. Keeffe. "DIABETES AND THE HEPATOBILIARY SYSTEM." Clinics in Liver Disease 2, no. 1 (February 1998): 119–31. http://dx.doi.org/10.1016/s1089-3261(05)70367-6.

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Masyuk, Anatoliy I., and Nicholas F. LaRusso. "Aquaporins in the hepatobiliary system." Hepatology 43, S1 (2006): S75—S81. http://dx.doi.org/10.1002/hep.20996.

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6

Maksimak, Martin, Elaine Wilt, A. Thompson Colley, and Archimedes Garbes. "Hemangioendothelioma of the Hepatobiliary System." Journal of Pediatric Gastroenterology and Nutrition 10, no. 1 (January 1990): 131–37. http://dx.doi.org/10.1097/00005176-199001000-00026.

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7

Brown, Rachel M., and Stefan G. Hübscher. "Infectious diseases of the hepatobiliary system." Diagnostic Histopathology 19, no. 3 (March 2013): 80–88. http://dx.doi.org/10.1016/j.mpdhp.2013.01.013.

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Brown, Rachel M. "Infectious diseases of the hepatobiliary system." Diagnostic Histopathology 23, no. 9 (September 2017): 405–13. http://dx.doi.org/10.1016/j.mpdhp.2017.07.001.

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Brown, Rachel Mary. "Infectious diseases of the hepatobiliary system." Diagnostic Histopathology 26, no. 12 (December 2020): 566–74. http://dx.doi.org/10.1016/j.mpdhp.2020.10.004.

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10

Benson, Mark D., and Mitesh R. Gandhi. "Ultrasound of the Hepatobiliary-pancreatic System." World Journal of Surgery 24, no. 2 (February 2000): 166–70. http://dx.doi.org/10.1007/s002689910029.

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11

Schubert, Timothy T. "Hepatobiliary system in sickle cell disease." Gastroenterology 90, no. 6 (June 1986): 2013–21. http://dx.doi.org/10.1016/0016-5085(86)90276-3.

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12

Marolf, Angela J. "Diagnostic Imaging of the Hepatobiliary System." Veterinary Clinics of North America: Small Animal Practice 47, no. 3 (May 2017): 555–68. http://dx.doi.org/10.1016/j.cvsm.2016.11.006.

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13

Pang, Zengfen, Xingli Wang, Yanfang Wu, Huan Zhang, Amei Huang, and Xianghong Li. "Construction and Empirical Study of Nursing Quality Evaluation Index System of Hepatobiliary Surgery Based on ERAS Concept." Computational and Mathematical Methods in Medicine 2022 (April 14, 2022): 1–7. http://dx.doi.org/10.1155/2022/1117880.

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Objective. To study the index system of enhanced recovery after surgery (ERAS) nursing evaluation, as a basis for the quality evaluation of hepatobiliary care, continue to improve the quality of hepatobiliary care. Methods. The 300 cases of hepatobiliary surgical diseases treated in our hospital from January 2019 to December 2020 were randomly selected as the subjects of this study. Through clinical trials, two groups of subjects were used, one for the ERAS care group and the traditional care group. Through the questionnaire survey and access to the relevant research data, statistical data analysis was performed using the SPSS 22.0 software. Metrics were analyzed as descriptive by mean, standard deviation, and coefficient of variation. The Visual Analogue Score (VAS) Hepatobiliary Surgery Nursing Service evaluation form, service evaluation form, postoperative incidence of adverse reaction rate, patient satisfaction, and readmission rate questionnaire were established from the aspects of structural quality and process quality. An index system of hepatobiliary surgery nursing quality evaluation based on the ERAS concept was constructed. Results. This study compared the degree of VAS pain through postoperative care. The ERAS care group scored significantly lower than in the traditional care group. Nursing patients based on ERAS are very satisfied with the quality of care services. By comparing patient postoperative adverse reactions, satisfaction, and readmission rates, the ERAS care group was significantly better than the traditional care group. It can be seen that a good nursing quality evaluation index system can truly and objectively reflect the level of nursing quality and promote the hospital to further improve the medical quality. Conclusion. The research on the construction of nursing quality evaluation index system of hepatobiliary surgery based on ERAS concept provides a more scientific evaluation standard for nursing quality evaluation of hepatobiliary surgery ERAS, creates conditions for digital and intelligent management of nursing quality, and provides a basis for formulating a unified nursing quality evaluation index system of hepatobiliary surgery. It is of practical significance to improve the nursing quality of ERAS in hepatobiliary surgery.
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Khatiwada, Sushma, Budhi Nath Adhikari, and Iju Shrestha. "Anatomical variation of intrahepatic biliary duct in cadaveric liver." Journal of Chitwan Medical College 9, no. 4 (December 27, 2019): 11–14. http://dx.doi.org/10.3126/jcmc.v9i4.26892.

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Background: Hepatobiliary system has many variations. Use of cadavers, intraoperative data and various imaging modalities are the commonly employed techniques for determining the anatomy of intrahepatic bile ducts. The vivid picture of hepatobiliary system is a must for hepatobiliary surgery and identification of frequency distribution of typical and atypical pattern and different types of atypical pattern are vital. This study aimed to uncover its frequency distribution and also to recognize the variations therein. Methods: An observational study was conducted in the Department of Anatomy, Kathmandu Medical College Teaching Hospital from July 2013 to June 2014 by taking 50 complete human cadaveric livers without evidence of injuries or previous operations. Livers were dissected, duct traced, colored, photographed and the findings were entered in a proforma. Results: Out of 50 dissected livers, 32 showed typical pattern (Type A, 64%) whereas 18 liver showed atypical pattern of confluence (36%). The type B pattern was seen in 6 (12%) and type C was seen in 8 of them (16%). Of these 8 cases, subtype C1 was observed in 6 livers (12%) and subtype C2 was found in 2 livers (4%). Type D was seen in 3 livers (6%). and all of them were of the subtype D1. There were no cases of subtype D2 and of type E. Type F was observed in a single case (2%). Conclusions: An accurate knowledge of the anatomical variations of the intrahepatic biliary tree is important for a successful hepatobiliay surgery.
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Khatiwada, Sushma, Budhi Nath Adhikari, and Iju Shrestha. "ANATOMICAL VARIATION OF INTRAHEPATIC BILIARY DUCT IN CADAVERIC LIVER." Journal of Chitwan Medical College 9, no. 4 (December 27, 2019): 11–14. http://dx.doi.org/10.54530/jcmc.82.

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Background: Hepatobiliary system has many variations. Use of cadavers, intraoperative data and various imaging modalities are the commonly employed techniques for determining the anatomy of intrahepatic bile ducts. The vivid picture of hepatobiliary system is a must for hepatobiliary surgery and identification of frequency distribution of typical and atypical pattern and different types of atypical pattern are vital. This study aimed to uncover its frequency distribution and also to recognize the variations therein. Methods: An observational study was conducted in the Department of Anatomy, Kathmandu Medical College Teaching Hospital from July 2013 to June 2014 by taking 50 complete human cadaveric livers without evidence of injuries or previous operations. Livers were dissected, duct traced, colored, photographed and the findings were entered in a proforma. Results: Out of 50 dissected livers, 32 showed typical pattern (Type A, 64%) whereas 18 liver showed atypical pattern of confluence (36%). The type B pattern was seen in 6 (12%) and type C was seen in 8 of them (16%). Of these 8 cases, subtype C1 was observed in 6 livers (12%) and subtype C2 was found in 2 livers (4%). Type D was seen in 3 livers (6%). and all of them were of the subtype D1. There were no cases of subtype D2 and of type E. Type F was observed in a single case (2%). Conclusions: An accurate knowledge of the anatomical variations of the intrahepatic biliary tree is important for a successful hepatobiliay surgery.
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16

Kulkarni, Dr Vishwanath S., and Dr Veeresh Hanchinal. "CT finding in neoplasms of Hepatobiliary system." International Journal of Radiology and Diagnostic Imaging 2, no. 2 (July 1, 2019): 04–06. http://dx.doi.org/10.33545/26644436.2019.v2.i2a.29.

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Marzoqi, Galal AL, Marco Alfonse, Ibrahim F. Moawad, and Mohamed Roushdy. "Ontology-based Approach for Hepatobiliary System Diseases." International Journal of e-Healthcare Information Systems 3, no. 1 (June 30, 2016): 80–89. http://dx.doi.org/10.20533/ijehis.2046.3332.2016.0012.

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Thappa, DevinderM, ShashiK Godara, Biju Pottakkatt, Abdoul Hamide, Jagadisan Barath, Malathi Munisamy, and MinuJ Chiramel. "Cutaneous manifestations in disorders of hepatobiliary system." Indian Dermatology Online Journal 8, no. 1 (2017): 9. http://dx.doi.org/10.4103/2229-5178.198760.

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19

Sauerland, Carmel, Constance Engelking, Rita Wickham, and David B. Pearlstone. "Cancers of the Pancreas and Hepatobiliary System." Seminars in Oncology Nursing 25, no. 1 (February 2009): 76–92. http://dx.doi.org/10.1016/j.soncn.2008.10.006.

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20

Mowat, Alex P. "Disorders of the hepatobiliary system in children." Current Opinion in Pediatrics 3, no. 6 (December 1991): 1009–14. http://dx.doi.org/10.1097/00008480-199112000-00013.

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21

Hadchouel, Michelle, and Olivier Bernard. "Disorders of the hepatobiliary system in children." Current Opinion in Pediatrics 4, no. 5 (October 1992): 792–97. http://dx.doi.org/10.1097/00008480-199210000-00011.

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22

Fuchs, Renate, and Theresia Thalhammer. "Editorial: Cell Biology of the Hepatobiliary System." Wiener Medizinische Wochenschrift 158, no. 19-20 (October 2008): 531–33. http://dx.doi.org/10.1007/s10354-008-0602-3.

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23

Astudillo, J. Andrés, Emanuel Sporn, Bolívar Serrano, and Rubén Astudillo. "Ascariasis in the Hepatobiliary System: Laparoscopic Management." Journal of the American College of Surgeons 207, no. 4 (October 2008): 527–32. http://dx.doi.org/10.1016/j.jamcollsurg.2008.05.020.

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24

Kravets, Ye B., M. A. Medvedev, I. A. Kolmatsuj, and Ye A. Birjulina. "State of hepatobiliary system at endocrinous pathology." Bulletin of Siberian Medicine 4 (December 30, 2005): 22–25. http://dx.doi.org/10.20538/1682-0363-2005-0-22-25.

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25

Smirnova, Svetlana Vital'evna, Anna Aleksandrovna Barilo, and Marina Viktorovna Smol'nikova. "Hepatobiliary system diseases as the predictors of psoriasis progression." Annals of the Russian academy of medical sciences 71, no. 2 (February 16, 2016): 102–8. http://dx.doi.org/10.15690/vramn636.

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Purpose of the study. To assess the state of the hepatobiliary system in psoriasis and psoriatic arthritis in order to establish a causal relationship and to identify clinical and functional predictors of psoriatic disease progression.Methods. The study included patients with extensive psoriasis vulgaris (n = 175) from the age of 18 to 66. Divided into 3 groups: 1 – psoriasis patients with isolated skin lesions (n = 77), 2 – patients with psoriatic arthritis (n = 98), 3 – apparently healthy blood donors (n = 30), matched by sex and age. The evaluation of functional state of the hepatobiliary system was performed by analysis of the clinical and anamnestic data and by the laboratory- instrumental methods.Results. Identified predictors psoriasis: triggers (stress and nutritional factor), increased total bilirubin, aspartate aminotransferase, alkaline phosphatase, gamma glutamyl transferase, eosinophilia, giardiasis, carriers of hepatitis C virus, and changes focal ductal formation in the liver , thickening of the walls of the gallbladder by ultrasound. Predictors of psoriatic arthritis: age over 50 years, dyspeptic complaints, the presence of hepatobiliary system diseases, the positive right hypochondrium syndrome, the clinical symptoms of chronic cholecystitis, excess body weight, high levels of bilirubin, cholesterol and low density lipoprotein, hepatomegaly, non-alcoholic fatty liver disease.Conclusion. High activity of hepatocytes cytolysis, cholestasis, inflammation, metabolic disorders can be considered psoriatic arthritis as a severe clinical stage psoriatic disease where the hepatobiliary system, in turn, is one of the main target organs in systemic psoriatic process. Non-alcoholic fatty liver disease and chronic cholecystitis are predictors of psoriatic disease progression.
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26

M. V. Luchak, O. Z. Hnateiko, N. S. Lukianenko, and S. O. Pechenyk. "Clinical and paraclinical characteristics of the hepatobiliary system among children who live in an ecologically unfavourable district." Bukovinian Medical Herald 17, no. 2 (66) (May 2, 2013): 80–82. http://dx.doi.org/10.24061/2413-0737.xvii.2.66.2013.70.

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A comparative analysis of the clinicoparaclinical manifestations of hepatobiliary pathology in 66 children, living under different ecological conditions has been carried out. It has been found out that ecologically conditioned pathology is of a nonspecific, polysystemic character in examined children. A high rate of early manifestations of hepatobiliary pathology has been diagnosed in the patients due to their living in the region contaminated by oil-processing products. The findings of the research have shown that a possible manifestation of a dysfunction of the hepatobiliary system in children from an ecologically unfavourable region is the onset of the biochemical signs of the syndrome of cholestasis.
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Winaya, Ida Bagus Oka, Anak Agung Ayu Mirah Adi, I. Ketut Berata, I. Made Kardena, Ida Bagus Windia Adnyana, and Ida Bagus Kade Suardana. "PATHOLOGICAL ALTERATION OF BALI CATTLE HEPATOBILIARY SYSTEM INFECTED WITH FASCIOLA GIGANTICA." Jurnal Veteriner 21, no. 4 (December 30, 2020): 654–61. http://dx.doi.org/10.19087/jveteriner.2020.21.4.654.

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Liver fluke infections is an important parasitic disease that common attack cattle, buffalo and others ruminant. The disease in the tropics is caused by Fasciola gigantica trematodes. Fasciolosis found in Bali cattle besides causing high economic loss also has the opportunity infect humans. This study aims to determine the pathology changes of Bali cattle hepatobiliary system infected by F. gigantica. In January 2019 were examined a hundred of liver tissue Bali cattle. Based on the sex as many as 75 bali cattle are cows and 25 are bulls. On macroscopic examination was found fifteen bali cattles in gallbladder containing of F. gigantica. In positive Fasciolosis the surface of liver look uneven with enlargement of lymph nodes. The tissue of Bali cattle liver infected with F. gigantica is cut into 1x1x1 cm and put in a pot that has been filled with 10% neutral buffered formaline. The fixed tissue then processed in a tissue processor and stained with hematoxylin-eosin (HE). Microscopic examination was found bile ducts proliferation and blocked of the lumen accompanied by cholangio cirrhosis. Found longitudinal pieces of Fasciola gigantica liver fluke surrounded by fibrous connective tissue and multifocal coagulative necrosis with fibroblast proliferation. In some location the infiltration of neutrophil cells around the bile ducts can also be seen. Congestion, bleeding, and neutrophil infiltration are also seen in areas of necrosis. In the bile duct wall bleeding, adenomatus hyperplasia, infiltration of mononuclear cells with mild intensity and foci of calcification are found. It can be concluded that there was a change with severe intensity accompanied by chronic inflammation in the hepatobiliary system of Bali cattle with Fasciolosis.
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Zhuntova, G. V., T. V. Azizova, M. V. Bannikova, and G. V. Sychugov. "Characteristics of malignant neoplasms of the hepatobiliary system in the cohort of occupationally-exposed workers." Ural Medical Journal 21, no. 1 (March 22, 2022): 4–12. http://dx.doi.org/10.52420/2071-5943-2022-21-1-4-12.

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Introduction. The etiology of malignant neoplasms (MN) of the hepatobiliary system is multifarious, so when assessing the impact of ionizing radiation on the occurrence of tumors of this localization, non-radiation factors should be considered. The aim of the study was to describe cases of hepatobiliary system disease in the cohort of employees hired at the main plants of FSUE Mayak Production Association (PA «Mayak») in 1948-1982, who were exposed to occupational chronic radiation. Materials and Methods. The cohort under study included 22,377 persons (25% were women). The frequency of individual risk factors was compared among morphologically confirmed cases of hepatobiliary cancer and among workers who had not been ill with tumors of the indicated localization. Results. Up to December 31, 2018, the cohort had 59 cases of liver MCC (59% hepatocellular carcinoma, 17% cholangiocarcinoma, 25% hemangiosarcoma, and 2% anaplastic cancer) and 34 cases of gallbladder and biliary tract MCC (100% adenocarcinoma). The incidence of chronic diseases of gallbladder and biliary tract, cholelithiasis was statistically significantly higher among cases of hepatobiliary MNS in comparison with uninfected workers. In addition, there was a higher share of persons who had contact with harmful industrial factors before employment at PA «Mayak», as well as those with chronic liver diseases, excessive body weight and obesity among liver cancer patients. Doses of occupational exposure were highest in workers with liver hemangiosarcomas. Discussion. The data were obtained testifying to a possible role of non-radiation factors and ionizing radiation in the development of hepatobiliary cancer in the workers of the cohort under study. A peculiarity of the cohort is a high proportion of hemangiosarcomas in the structure of hepatic cancer. Conclusion. The non-radiational factors that, along with occupational exposure, could influence the incidence of hepatobiliary cancer among PA «Mayak» workers have been singled out. An analysis of risk caused by radiation and non-radiation factors is required to clarify the results of the study.
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Doush, Wael, Mohammed A/Galil, and Shakir Ibrahim. "Anatomical variations of the hepatobiliary system in Sudanese patients undergoing endoscopic retrograde cholangiopancreatography (ERCP)." International Journal of Medicine 5, no. 1 (April 2, 2017): 105. http://dx.doi.org/10.14419/ijm.v5i1.7394.

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Background: The meticulous identification of the hepatobiliary tree system normal anatomy during surgical operations is crucial in iatrogenic injury prevention. Equally important, an understanding of the congenital variations of biliary and vascular anatomy, as the literature abounds with reports of specific anatomical variations, and their surgical implications.Aim: This study aimed to study the presence of anatomical variations within the hepatobiliary system in Sudanese population undergoing endoscopic retrograde cholangiopancreatography (ERCP).Patients and methods: The records of patients undergoing ERCP in Soba University Hospital during 2004 to 2008 were analyzed. There were 277 Sudanese patients who had complained of right hypochondrial abdominal pain & history of jaundice (obstructive jaundice) that underwent ERCP were included within this study. The exclusion criteria included the following: Sudanese patients in whom ERCP failed or patients who had advanced hepatobiliary disease like cancers, strictures either cancerous or iatrogenic, fistula and iatrogenic biliary leak.Results: The analysis of 277 Sudanese patients undergoing ERCP of the hepatobiliary system showed the following results regarding the variations: The choledochal cyst type one (fusiform type) was present in 3 (1.08%) patients; very low cystic duct insertion (parallel) was present in 1 (0.36%) patient and long cystic duct was present in 3 (1.08%) patients. The ampulla of Vater size variations occurred as A) Normal in 158 (57%) patient, B) Small in 56 (20.2%) patients, C) Large in 29 (10.5%) patients, D) Periampullary diverticula in 4 (1.4%) patients and E) unclassified in 30 (10.8%) patients. Other forms of congenital anomalies were not found.Conclusion: The using of endoscopic retrograde cholangiopancreatography (ERCP) is a reliable radiological method for depicting congenital anomalies of the hepatobiliary system, but it is an invasive procedure.
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Furdychko, Anastasia I., Marta P. Ilchyshyn, Irena R. Fedun, Adriana Ya Barylyak, Oksana M. Slaba, and Lesya M. Khoroz. "PERIODONTAL STATUS IN PATIENTS WITH DISEASES OF HEPATOBILIARY SYSTEM, BURDENED WITH TOBACCO AND DRUG ADDICTION." Wiadomości Lekarskie 73, no. 3 (2020): 517–20. http://dx.doi.org/10.36740/wlek202003121.

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The aim: To study the effect of drug addiction and smoking on the status of periodontal tissues in patients with hepatobiliary pathology. Materials and methods: 58 smokers, 63 drug addicts with hepatobiliary pathology were examined and 92 persons of comparison group (with inflammatory periodontal diseases affected by hepatobiliary pathology, without addiction). Examination of patients included determination of iodine number by Svrakov, S-L and Stallard hygiene indices, PMA index and index PBI. Results: The results of examination of smokers are worse in patients with cirrhosis than in patients with chronic toxic hepatitis and non-alcoholic steatohepatitis and also the results of these two groups was significantly worse than that of the comparison group (iodine number by Svrakov – 1,4 times and 1,3 times higher, PMA index – 1,7 times and 1,4 times worse, in accordance). The results of the study showed that drug addicts patients are worse values in patients with cirrhosis than in patients with chronic toxic hepatitis and non-alcoholic steatohepatitis and also the results of these two groups was significantly worse than that of the comparison group (iodine number by Svrakov – 1,5 times and 1,4 times higher, PMA index – 1,7 times and 1,5 times worse, in accordance). Conclusions: Presence of hepatobiliary pathology in smokers and drug addicts increases the risk of periodontal diseases.
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Aoki, Takeshi, Tomokazu Kusano, Kazuhiko Saito, Tatuya Yamazaki, Takahito Hirai, Koudai Tomioka, Hidetaka Shibata, et al. "Simulation and Navigation System for Hepatobiliary-Pancrearic Surgery." Journal of Japan Society of Computer Aided Surgery 22, no. 2 (2020): 111–19. http://dx.doi.org/10.5759/jscas.22.111.

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Shadrin, O. H., and O. V. Shutova. "Therapy optimization of hepatobiliary system pathology in children." SOVREMENNAYA PEDIATRIYA, no. 3(91) (April 29, 2018): 112–18. http://dx.doi.org/10.15574/sp.2018.91.112.

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Anjamrooz, Seyed Hadi, and Hassan Azari. "Coexistence of multiple anomalies in the hepatobiliary system." Anatomy & Cell Biology 45, no. 1 (2012): 62. http://dx.doi.org/10.5115/acb.2012.45.1.62.

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34

Davis, Lawrence P., and Kathleen McCarroll. "Correlative imaging of the liver and hepatobiliary system." Seminars in Nuclear Medicine 24, no. 3 (July 1994): 208–18. http://dx.doi.org/10.1016/s0001-2998(05)80011-x.

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35

BLENDIS, L. "What are helicobacter doing in the hepatobiliary system?" Gastroenterology 129, no. 2 (August 2005): 761–63. http://dx.doi.org/10.1016/j.gastro.2005.05.068.

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36

Whitcomb, David. "The Gastrointestinal System: Gastrointestinal, Nutritional and Hepatobiliary Physiology." Gastroenterology 148, no. 3 (March 2015): 659–60. http://dx.doi.org/10.1053/j.gastro.2015.01.022.

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37

Gupta, Mahesh, Manoj Gupta, and Pooja Gupta. "STUDY OF HEPATOBILIARY DUCTAL SYSTEM BY LAPAROSCOPIC CHOLANGIOGRAPHY." Journal of Evolution of Medical and Dental Sciences 4, no. 99 (December 10, 2015): 16447–50. http://dx.doi.org/10.14260/jemds/2015/2440.

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Blendis, Laurie. "What are helicobacter doing in the hepatobiliary system?" Gastroenterology 129, no. 2 (August 2005): 761–63. http://dx.doi.org/10.1053/j.gastro.2005.05.068.

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Okamoto, Tomoyoshi, Shinji Onda, Michinori Matsumoto, Takeshi Gocho, Yasuro Futagawa, Shuichi Fujioka, Katsuhiko Yanaga, Naoki Suzuki, and Asaki Hattori. "Utility of augmented reality system in hepatobiliary surgery." Journal of Hepato-Biliary-Pancreatic Sciences 20, no. 2 (March 8, 2012): 249–53. http://dx.doi.org/10.1007/s00534-012-0504-z.

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40

Larson, Martha Moon. "Ultrasound Imaging of the Hepatobiliary System and Pancreas." Veterinary Clinics of North America: Small Animal Practice 46, no. 3 (May 2016): 453–80. http://dx.doi.org/10.1016/j.cvsm.2015.12.004.

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41

Abaturov, A. E., and V. L. Babуch. "The world of microRNAs of the hepatobiliary system." CHILD`S HEALTH 16, no. 1 (April 6, 2021): 84–93. http://dx.doi.org/10.22141/2224-0551.16.1.2021.226462.

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The scientific review presents the significance of the world of microRNAs of the hepatobiliary system. For writing the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library, CyberLeninka databases. It is emphasized that microRNAs in cells play an important role in regulating the activity of gene expression and control numerous physiological processes, such as metabolism, proliferation, differentiation, apoptosis of cells. The association of some diseases with changes in the content of microRNAs in the peripheral bloodstream is shown. The article presents a brief description of the group of non-coding RNAs. The characteristic of the basic microRNA databases with display of electronic addresses is given. Both traditional methods based on amplification technology and new detection methods (next-generation sequencing, electrochemical detection based on enzyme signal amplification, identification by ligation and application of gold nanoparticles) are used to determine microRNAs. The authors compare different methods of microRNA detection. It is noted that overexpression or inhibition of the generation of specific microRNAs is accompanied by impaired liver function and the development of diseases of the hepatobiliary system. Changes in some microRNAs in serum or liver tissue have been shown to be highly diagnostic markers of some liver diseases. Thus, the identification of changes in the level of representativeness of certain microRNAs may have valuable diagnostic information to the practitioner, and the impact on the processes of formation and maturation of microRNAs by drugs is a new direction in the treatment of a wide range of diseases. The modern idea of the diagnostic value of microRNAs in di­seases of the biliary tract in children and the possibilities of drug management of the activity of the process of their generation are of particular interest.
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Crawford, Laura Wilding, Julie F. Foley, and Susan A. Elmore. "Histology Atlas of the Developing Mouse Hepatobiliary System with Emphasis on Embryonic Days 9.5-18.5." Toxicologic Pathology 38, no. 6 (August 30, 2010): 872–906. http://dx.doi.org/10.1177/0192623310374329.

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Animal model phenotyping, in utero exposure toxicity studies, and investigation into causes of embryonic, fetal, or perinatal deaths have required pathologists to recognize and diagnose developmental disorders in spontaneous and engineered mouse models of disease. In mammals, the liver is the main site of hematopoiesis during fetal development, has endocrine and exocrine functions important for maintaining homeostasis in fetal and adult life; and performs other functions including waste detoxification, production and removal of glucose, glycogen storage, triglyceride and fatty acid processing, and serum protein production. Due to its role in many critical functions, alterations in the size, morphology, or function(s) of the liver often lead to embryonic lethality. Many publications and websites describe individual aspects of hepatobiliary development at defined stages. However, no single resource provides a detailed histological evaluation of H&E-stained sections of the developing murine liver and biliary systems using high-magnification and high-resolution color images. The work herein provides a histology atlas of hepatobiliary development between embryonic days 9.5-18.5. Although the focus of this work is normal hepatobiliary development, common defects in liver development are also described as a reference for pathologists who may be asked to phenotype mice with congenital, inherited, or treatment-related hepatobiliary defects. Authors’ note: All digital images can be viewed online at https://niehsimagesepl-inc.com with the username “ToxPathLiver” and the password “embryolivers.”
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43

Pletnev, V. V. "EVALUATING THE EFFECTIVENESS OF PLETNEV DROPS NO. 5 IN THE TREATMENT OF DISEASES OF THE HEPATOBILIARY SYSTEM IN ADULTS PATIENTS." EurasianUnionScientists 3, no. 3(72) (April 15, 2020): 32–35. http://dx.doi.org/10.31618/esu.2413-9335.2020.3.72.632.

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Taking Pletnev drops No. 5 inside in the treatment of diseases of the hepatobiliary system in adults patients, helps restore of peripheral blood (platelets) and biochemical parameters of blood (aminotransferases, alkaline phosphatase, glutamate transpeptidase, bilirubin) in adult patients with diseases of the hepatobiliary system. Pletnev drops No. 5 do not cause undesirable side effects, are well tolerated, do not cause addiction and have the possibility of long-term use.
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Chan, Kun-Ming, Chih-Hsien Cheng, Tsung-Han Wu, Chen-Fang Lee, Ting-Jung Wu, Hong-Shiue Chou, and Wei-Chen Lee. "De Novo Endotoxin-Induced Production of Antibodies against the Bile Salt Export Pump Associated with Bacterial Infection following Major Hepatectomy." BioMed Research International 2018 (2018): 1–9. http://dx.doi.org/10.1155/2018/6197152.

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Background. Clinically severe infection-related inflammation after major liver resection may cause hyperbilirubinemia. This study aims to clarify the impact of bacterial infection and endotoxins on the hepatobiliary transporter system and to explore possible mechanisms of endotoxin-related postoperative hyperbilirubinemia.Method. Mice that underwent major hepatectomy with removal of at least 70% of liver volume were exposed to lipopolysaccharide (LPS) at different dosages. Subsequently, hepatobiliary transporter compounds related to bile salt excretion were further investigated.Results. The expression of genes related to hepatobiliary transporter compounds was not significantly different in the liver tissue of mice after major hepatectomy and LPS exposure. However, bile salt export pump (BSEP) protein expression within the liver tissue of mice treated with LPS after major hepatectomy was relatively weaker and was even further reduced in the high-dose LPS group. The formation of antibodies against the BSEP in response to endotoxin exposure was also detected.Conclusion. This study illustrates a possible mechanism whereby the dysfunction of hepatobiliary transporter systems caused by endotoxin-induced autoantibodies may be involved in the development of postoperative jaundice associated with bacterial infection after major hepatectomy.
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Konnov, Pavel E., and E. V. Orlov. "CHRONIC ACTINIC DERMATITIS AND PATHOLOGY OF THE DIGESTIVE TRACT." Russian Journal of Skin and Venereal Diseases 20, no. 5 (December 15, 2017): 293–96. http://dx.doi.org/10.18821/1560-9588-2017-20-5-293-296.

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Chronic actinic dermatitis (CAD) is characterized by itchy eczematous lesions on areas of skin exposed to sunlight. The disease affects men middle-aged and elderly. Three criteria was taken into account to diagnose CAD: the effects of the minimum erythemal doses of UVA and UVB, a persistent eczematous lesions in areas exposed to radiation and sometimes non-irradiated sites, and histopathological changes resembling chronic eczema. The eczematous process of the skin develops as a result of a number of factors that lead to sensitization of the organism, including in the pathology of the digestive tract and the hepatobiliary system. A correlation was found between the severity of eczematous skin lesions and the severity of the digestive tract disease. Material and methods. Under the care of the Department of dermatology and venereology Clinics of the Samara state medical University of Minzdrav of Russia were 65 men with CAD, among them 61 (93.9%) patients are over 40 years old. The pathology of the digestive tract and the hepatobiliary system was detected in 51 (78.6%) patients. Concomitant diseases of the digestive tract and the hepatobiliary system had a latent period and were identified for the first time due to a comprehensive survey in 37 (57%) patients. Results. In most cases, CAD on the background of the digestive system disease, there was a moderate and severe course of the eczematous process. The frequency of occurrence of reflux esophagitis, superficial and atrophic gastritis, duodenogastric reflux, as well as the combined pathology of the hepatobiliary system was maximal in patients with the most severe course of the eczematous process. The majority of patients without pathology of the digestive tract and hepatobiliary system had minimal skin manifestations of eczema.
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46

Kravets, Ye B., Ye A. Biryulina, and Z. G. Mironova. "Hepatobiliary function in children with insulin-dependent diabetes mellitus." Problems of Endocrinology 41, no. 4 (August 15, 1995): 15–17. http://dx.doi.org/10.14341/probl11453.

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The hepatobiliary system plays the crucial role in the development of metabolic disorders in diabetics. Involvement of the hepatobiliary system may develop at the early stages of diabetes mellitus. The present study was aimed at elucidation of the specific features of bile excretion and production in children with type I diabetes making use of present-day diagnostic methods. Fifty-two patients with type 1 diabetes aged 6 to 15 and 20 healthy controls were examined. Besides common clinical studies, fractionated duodenal probing followed by biochemical analysis of the bile, ultrasonic examination of the hepatobiliary system, and dynamic hepatobiliscintigraphy were carried out. Typical changes in liver parenchyma developing after fatty hepatosis type were found to play the main role in the structure of hepatobiliary involvement occurring in insulin-dependent diabetes. Disorders of bile excretion are caused by dyskinetic disorders of extrahepatic bile duct and choleresis changes. Bile excretion arrhythmia manifests most frequently as hypertensive dyskinesia. In patients with a longstanding disease bile excretion changes are mainly due to increased tone of the sphincter of Oddi and decelerated contractility of the gallbladder. Biochemical composition of the bile was characterized by decreased concentration of bile acids, phospholipids, and bilirubin, by a lower cholate-cholesterol coefficient, and increased levels of cholesterol and total lipids.
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47

Matveev, A. V. "Pharmacokinetic modeling in dynamic scintigraphy of the hepatobiliary system." Problems of Biological Medical and Pharmaceutical Chemistry 23, no. 9 (2020): 32–41. http://dx.doi.org/10.29296/25877313-2020-09-05.

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48

Kharchenko, V. V., and H. A. Anokhina. "Selection of hepatoprotector in multimorbid diseases of hepatobiliary system." Modern Gastroenterology, no. 4 (September 28, 2018): 36–42. http://dx.doi.org/10.30978/mg-2018-3-36.

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Parkhomenko, L. K., O. A. Budreiko, L. A. Strashok, G. V. Kosovtsova, E. M. Zavelya, M. Yu Isakova, and A. V. Yeshchenko. "State of the hepatobiliary system in boys with hypoandrogenism." Modern Gastroenterology, no. 5 (October 31, 2018): 19–24. http://dx.doi.org/10.30978/mg-2018-5-19.

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Tyshchenko, O. M., E. V. Mushenko, R. M. Smachylo, A. L. Sochneva, and I. B. Babinkina. "Hepatobiliary system surgery after operations on stomach and duodenum." Surgery of Ukraine, no. 3 (September 19, 2018): 17–24. http://dx.doi.org/10.30978/su2018-3-17.

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