Academic literature on the topic 'Hepatocyte growth facter'

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Journal articles on the topic "Hepatocyte growth facter"

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FURUKAWA, M., Y. MAGAMI, D. NAKAYAMA, F. MORIYASU, T. NIKAIDO, and T. SAKAI. "Possible involvement of p21/waf1 in the growth of hepatocellular carcinoma cells by hepatocyte growth facter (HGF)." Gastroenterology 120, no. 5 (2001): A360. http://dx.doi.org/10.1016/s0016-5085(01)81791-1.

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Furukawa, Masaya, Yasushi Magami, Daiju Nakayama, Fuminori Moriyasu, Toshio Nikaido, and Toshiyuki Sakai. "Possible involvement of p21/waf1 in the growth of hepatocellular carcinoma cells by hepatocyte growth facter (HGF)." Gastroenterology 120, no. 5 (2001): A360. http://dx.doi.org/10.1016/s0016-5085(08)81791-x.

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Nagoshi, Sumiko, Shinichi Ota, and Kenji Fujiwara. "Polyamines may be involved in hepatocyte growth facter-stimulated restitution of rabbit gastric epithelial cells in primary culture." Gastroenterology 118, no. 4 (2000): A1281. http://dx.doi.org/10.1016/s0016-5085(00)80974-9.

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Gupta, Sanjeev, Pankaj Rajvanshi, Emma Aragona, Chang-Don Lee, Purnachandra R. Yerneni, and Robert D. Burk. "Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion." American Journal of Physiology-Gastrointestinal and Liver Physiology 276, no. 3 (1999): G629—G638. http://dx.doi.org/10.1152/ajpgi.1999.276.3.g629.

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To understand regulation of transplanted hepatocyte proliferation in the normal liver, we used genetically marked rat or mouse cells. Hosts were subjected to liver injury by carbon tetrachloride (CCl4), to liver regeneration by a two-thirds partial hepatectomy, and to hepatocellular DNA synthesis by infusion of hepatocyte growth factor for comparative analysis. Transplanted hepatocytes were documented to integrate in periportal areas of the liver. In response to CCl4 treatments after cell transplantation, the transplanted hepatocyte mass increased incrementally, with the kinetics and magnitude
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Lilja, Helene, Pierre Blanc, Achilles A. Demetriou, and Jacek Rozga. "Response of Cultured Fetal and Adult Rat Hepatocytes to Growth Factors and Cyclosporine." Cell Transplantation 7, no. 3 (1998): 257–66. http://dx.doi.org/10.1177/096368979800700304.

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Hepatocyte transplantation is a promising alternative to orthotopic liver transplantation in experimental animal models with genetic disorders of liver metabolism and liver failure. Fetal hepatocytes have several characteristics that make them potentially suitable as donor cells. In contrast to adult hepatocytes, fetal hepatocytes are thought to be highly proliferative, which may facilitate engraftment, expansion of transplanted cell population, and gene transfer requiring active DNA synthesis. The present study was undertaken to evaluate the proliferative capacity of fetal and adult rat hepat
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Watanabe, Y., H. Osaki, and T. Akaike. "TNF-alpha bifunctionally induces proliferation in primary hepatocytes: role of cell anchorage and spreading." Journal of Immunology 159, no. 10 (1997): 4840–47. http://dx.doi.org/10.4049/jimmunol.159.10.4840.

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Abstract In the absence of a growth factor or an appropriate extracellular matrix (ECM), cells are arrested in the G0/G1 phase. In this report, we demonstrate the evidence that TNF-alpha induced DNA synthesis of primary mouse hepatocytes in vitro by activating two distinct pathways. TNF-alpha induced drastic spreading of hepatocytes on hydrophobic plastic, while the adhesion was not influenced. The effect was time and dose dependent. The cell spreading was accompanied by the phosphorylation of paxillin, indicating the stimulation of focal adhesion molecules. TNF-alpha-induced spreading of hepa
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Block, G. D., J. Locker, W. C. Bowen, et al. "Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium." Journal of Cell Biology 132, no. 6 (1996): 1133–49. http://dx.doi.org/10.1083/jcb.132.6.1133.

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Mature adult parenchymal hepatocytes, typically of restricted capacity to proliferate in culture, can now enter into clonal growth under the influence of hepatocyte growth factor (scatter factor) (HGF/SF), epidermal growth factor (EGF), and transforming growth factor alpha (TGFalpha) in the presence of a new chemically defined medium (HGM). The expanding populations of hepatocytes lose expression of hepatocyte specific genes (albumin, cytochrome P450 IIB1), acquire expression of markers expressed by bile duct epithelium (cytokeratin 19), produce TGFalpha and acidic FGF and assume a very simpli
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Wei, Miaomiao, Xinlong Yan, Xin Xin, Haiqiang Chen, Lingling Hou, and Jinhua Zhang. "Hepatocyte-Specific Smad4 Deficiency Alleviates Liver Fibrosis via the p38/p65 Pathway." International Journal of Molecular Sciences 23, no. 19 (2022): 11696. http://dx.doi.org/10.3390/ijms231911696.

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Liver fibrosis is a wound-healing response caused by the abnormal accumulation of extracellular matrix, which is produced by activated hepatic stellate cells (HSCs). Most studies have focused on the activated HSCs themselves in liver fibrosis, and whether hepatocytes can modulate the process of fibrosis is still unclear. Sma mothers against decapentaplegic homologue 4 (Smad4) is a key intracellular transcription mediator of transforming growth factor-β (TGF-β) during the development and progression of liver fibrosis. However, the role of hepatocyte Smad4 in the development of fibrosis is poorl
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Bilezikçi, Banu, Asuman Nihan Haberal, and Beyhan Demirhan. "Hepatocyte Growth Factor in Patients with Three Different Stages of Chronic Liver Disease including Hepatocellular Carcinoma, Cirrhosis and Chronic Hepatitis: An Immunohistochemical Study." Canadian Journal of Gastroenterology 15, no. 3 (2001): 159–65. http://dx.doi.org/10.1155/2001/930629.

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BACKGROUND AND AIMS: The specific role of hepatocyte growth factor in liver disease is unknown. The presence and density of this factor in patients with three different stages of liver disease were investigated, with the aim of assessing its prognostic significance.PATIENTS AND METHODS: Liver specimens from patients with chronic hepatitis (n=20), cirrhosis (n=20), hepatocellular carcinoma (n=30) and normal livers (n=20) were immunohistochemically stained to determine the presence and density of hepatocyte growth factor.RESULTS: There were significantly more hepatocyte growth factor-positive Ku
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Liu, Ke-Xin, Yukio Kato, Tai-Ichi Kaku, Kunio Matsumoto, Toshikazu Nakamura, and Yuichi Sugiyama. "Protamine enhances the proliferative activity of hepatocyte growth factor in rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 274, no. 1 (1998): G21—G28. http://dx.doi.org/10.1152/ajpgi.1998.274.1.g21.

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The effect of protamine on the proliferative activity of hepatocyte growth factor (HGF) was examined in α-naphthyl isothiocyanate-intoxicated rats. Protamine preinjection increased the hepatocyte labeling index induced by HGF four- to fivefold. A similar effect was also observed in partially hepatectomized rats. Because a cell surface heparin-like substance can bind to HGF and protamine has an affinity for heparin, protamine may affect HGF pharmacokinetics. In fact, protamine injection caused a transient increase in plasma HGF concentrations after administration of HGF and, in vitro, protamine
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Dissertations / Theses on the topic "Hepatocyte growth facter"

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Kolatsi, Maria. "Hepatocyte growth factor and renal morphogenesis." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243452.

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Sigurđardóttir, Anna Guđný. "Targeting hepatocyte growth factor/scatter factor for drug discovery using a fragment-based approach." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610356.

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Wan, Kai-fung. "Hepatocyte growth factor and met receptor signaling in nasopharyngeal carcinoma cell migration and invasion." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39557029.

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Cook, Nathan Luke Meredith. "Immunoregulation by hepatocyte growth factor in malignant mesothelioma." Thesis, Cardiff University, 2008. http://orca.cf.ac.uk/54490/.

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This thesis is an investigation into effect of elevated levels of hepatocyte growth factor (HGF) on immune responses. High levels of HGF are found in cancer such as in MPM patient serum and pleural fluid. However, little is known about the consequence of high HGF levels on the development and function of dendritic cells and contribution of these effects to tumour immune evasion. A pre-treatment in vitro model system was applied to study the effects of high HGF concentrations on the development of dendritic cells (DC) from monocytes. The effects of HGF on the phenotype of dendritic cell, functi
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Vasiliauskas, Juozas. "Hepatocyte Growth Factor-Like protein In prostate tumorigenesis." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1428070127.

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Zhou, Hongyan. "Hepatocyte growth factor-met signaling in ovarian cancer progression." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B36845346.

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Johansson, Conny M. "Biophysical characterisation of the hepatocyte growth factor-glycosaminoglycan interaction." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/9904.

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Glycosaminoglycans (GAGs) such as heparin, heparan sulfate (HS), chondroitin sulfate (CS) and dermatan sulfate (DS) are sulfated polysaccharides that exist on animal cell surfaces and in the extracellular matrix. GAGs are important in providing structural and hydrating support and interaction points for proteins of varied functions, for example growth factors and homeostasis regulatory proteins. Hepatocyte Growth Factor (HGF) is a protein growth factor that regulates cell growth, survival, proliferation, chemotaxis, cell morphology, tissue regeneration and angiogenesis. It is involved in embry
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Xu, Jianyu. "Mutations in the hepatocyte nuclear factor 1 and glucokinase genes in Southern Chinese patients with early-onset type 2 diabetes." Click to view the E-thesis via HKUTO, 2002. http://sunzi.lib.hku.hk/hkuto/record/B42576854.

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Holmes, Oliver. "Functional studies and protein engineering of hepatocyte growth factor/scatter factor." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604185.

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Signalling <i>via </i>the receptor Met, HGF/SF has multiple essential roles in development and the wound response of vertebrate organisms and can activate several pathways, leading to cell survival, cell proliferation, increased motility and invasion. The aim of my research was to investigate the function of individual domains of HGF/SF and to find protein fragments with good affinity for Met. Some of these fragments were then engineered based on structural information in order to produce an antagonist of HGF/SF-Met signalling. As this antagonist could be easily produced in protein form it cou
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McKinnon, Heather Joanne. "The role of hepatocyte growth factor/scatter factor in vascular remodelling." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625061.

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Books on the topic "Hepatocyte growth facter"

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Boros, Peter. Hepatocyte growth factor: The basic principles. R.G. Landes, 1999.

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1948-, Goldberg I. D., and Rosen E. M, eds. Hepatocyte growth factor-scatter factor (HGF-SF) and the C-met receptor. Birkhäuser, 1992.

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Deakin, Jonathan Andrew. The binding and regulation of hepatocyte growth factor by heparan sulphite. University of Manchester, 1994.

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Fletcher, Karin. Modulation of growth factor responses in hepatocytes isolated from phenobarbitone treated mice. University of Birmingham, 1996.

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Somerset, David Alan. Hepatocyte growth factor (HGF) and its receptor c-met, in healthy and pathological human placentae. University of Birmingham, 2001.

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Hodges, Nikolas John. Potentiation of epidermal growth factor mitogenicity by phenobarbitone in primary cultures of rat hepatocytes. University of Birmingham, 1999.

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To, Christine Ting Ting. Overexpression of hepatocyte growth factor receptor/Met suppresses tumorigenecity of NCI-H1264 lung squamous carcimona cells. National Library of Canada, 1998.

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Harding, Helen Louise. The regulation of PEPCK gene expression by insulin and epidermal growth factor in rat hepatocytes. University of Manchester, 1995.

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Boros, Peter. Hepatocyte Growth Factor: The Basic Principles. Landes Bioscience, 2002.

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Boros, Peter. Hepatocyte Growth Factor: The Basic Principles (Medical Intelligence Unit). R. G. Landes, 2000.

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Book chapters on the topic "Hepatocyte growth facter"

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Bottaro, Donald P., Vittoria Cioce, Andrew M. L. Chan, David H. Adams, and Jeffrey S. Rubin. "Hepatocyte Growth Factor." In Growth Factors and Wound Healing. Springer New York, 1997. http://dx.doi.org/10.1007/978-1-4612-1876-0_18.

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Holdenrieder, S., and P. Stieber. "Hepatocyte growth factor." In Lexikon der Medizinischen Laboratoriumsdiagnostik. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_1435-1.

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Holdenrieder, S., and P. Stieber. "Hepatocyte growth factor." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_1435.

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Salajegheh, Ali. "Hepatocyte Growth Factor." In Angiogenesis in Health, Disease and Malignancy. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-28140-7_23.

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Christoffersen, Thoralf, G. Hege Thoresen, Olav F. Dajani, et al. "Mechanisms of hepatocyte growth regulation by hormones and growth factors." In The Hepatocyte Review. Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-3345-8_15.

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Gallo, Simona, Paolo Maria Comoglio, and Tiziana Crepaldi. "Hepatocyte Growth Factor Receptor." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101684.

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Sato, Hiroki, Shunsuke Aoki, Takashi Kato, and Kunio Matsumoto. "HGF (Hepatocyte Growth Factor)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101701.

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Gallo, Simona, Paolo Maria Comoglio, and Tiziana Crepaldi. "Hepatocyte Growth Factor Receptor." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101684-1.

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Sato, Hiroki, Shunsuke Aoki, Takashi Kato, and Kunio Matsumoto. "HGF (Hepatocyte Growth Factor)." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101701-1.

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Gómez-Lechón, María José, Isabel Guillén, M. J. Teresa Donato, Xavier Ponsoda, Ramiro Jover, and José V. Castell. "Proliferative response and metabolic effects of growth factors in human hepatocytes." In The Hepatocyte Review. Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-3345-8_16.

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Conference papers on the topic "Hepatocyte growth facter"

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Kawas, Leen H., Joseph W. Harding, Brent J. Yamamoto, and John W. Wright. "Abstract 1356: The Hinge (linker) region of the Hepatocyte Growth Factor (HGF) peptide sequence can act as Hepatocyte Growth Factor/c-Met inhibitor." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1356.

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Nanjo, Shigeki, Tadaaki Yamada, Shinji Takeuchi, and Seiji Yano. "Abstract 1896: Hepatocyte growth factor induces resistance to anti-epidermal growth factor receptor antibody in lung cancer." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1896.

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Krishnaveni, MS, B. Zhou, BC Willis, ED Crandall та Z. Borok. "Hepatocyte Growth Factor (HGF) Attenuates Transforming Growth Factor-β-Induced Epithelial Mesenchymal Transition in Alveolar Epithelial Cells." У American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5293.

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Guyette, Jacques P., and Glenn R. Gaudette. "Treating mesenchymal stem cells with hepatocyte growth factor enhances cardiac markers." In 2009 IEEE 35th Annual Northeast Bioengineering Conference. IEEE, 2009. http://dx.doi.org/10.1109/nebc.2009.4967625.

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Grasman, Jonathan M., Raymond L. Page, Tanja Dominko, and George D. Pins. "Enhancing cell recruitment onto crosslinked fibrin microthreads with hepatocyte growth factor." In 2014 40th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2014. http://dx.doi.org/10.1109/nebec.2014.6972802.

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Day, RM, O. Mungunsukh, and YH Lee. "A Modified L. Monocytogenes Internalin B Peptide Is a Hepatocyte Growth Factor Mimetic." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5365.

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Park, Joo Hun, Shunichiro Iwasawa, Jun Ikari, et al. "Prostaglandin E Stimulates Lung Fibroblasts Hepatocyte Growth Factor Release Through The EP2 Receptor." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1924.

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SJ, Arun, Xu Z, E. Fiala-Beer, et al. "Abstract LB-395: Hepatocyte growth factor: a potential therapeutic target in pancreatic cancer." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-395.

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Lee, Young H., Ognoon Mungunsukh, and Regina M. Day. "Hepatocyte Growth Factor Abrogates Angiotensin II-induced Apoptosis In Primary Lung Endothelial Cells." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4927.

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Sommer, Philip, Michael Schreinlechner, Maria Noflatscher, et al. "Hepatocyte growth factor as indicator for sublcinical atherosclerosis as measured by 3D-Ultrasound." In 46. Dreiländertreffen der DEGUM in Zusammenarbeit mit ÖGUM & SGUM. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1772450.

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Reports on the topic "Hepatocyte growth facter"

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Knudsen, Beatrice S. Hepatocyte Growth Factor and Interleukin-6 in Prostate Cancer Bone Metastasis. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada435856.

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Knudsen, Beatrice S. Hepatocyte Growth Factor and Interleukin-6 in Prostate Cancer Bone Metastasis. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada428439.

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Knudesen, Beatrice S. Hepatocyte Growth Factor and Interleukin-6 in Prostate Cancer Bone Metastasis. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada416620.

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Knudsen, Beatrice S. Hepatocyte Growth Factor and Interleukin-6 in Prostate Cancer Bone Metastasis. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada467982.

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Siegfried, Jill. Targeting the Hepatocyte Growth Factor Pathway for the Treatment of Breast Cancer. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada383623.

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Ross, Bernard A. Adjuvant Action of Hepatocyte Growth Factor in Vitamin D Therapy of Androgen-Unresponsive Prostate Cancer. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada401687.

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Lee, Young H. Mechanism of Hepatocyte Growth Factor Inhibition of Angiotensin II-induced Apoptosis in Primary Lung Cells. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ad1013415.

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Smith, Kyle T. Analysis of Progestin Effects on Hepatocyte Growth Factor Signaling Pathways in Relation to Proliferation and Alveolar Morphogenesis of Normal Mammary Epithelial Cells in Vitro. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada416749.

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