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Dissertations / Theses on the topic 'Hepatocyte growth facter'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Kolatsi, Maria. "Hepatocyte growth factor and renal morphogenesis." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243452.

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2

Sigurđardóttir, Anna Guđný. "Targeting hepatocyte growth factor/scatter factor for drug discovery using a fragment-based approach." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610356.

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3

Wan, Kai-fung. "Hepatocyte growth factor and met receptor signaling in nasopharyngeal carcinoma cell migration and invasion." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39557029.

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4

Cook, Nathan Luke Meredith. "Immunoregulation by hepatocyte growth factor in malignant mesothelioma." Thesis, Cardiff University, 2008. http://orca.cf.ac.uk/54490/.

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This thesis is an investigation into effect of elevated levels of hepatocyte growth factor (HGF) on immune responses. High levels of HGF are found in cancer such as in MPM patient serum and pleural fluid. However, little is known about the consequence of high HGF levels on the development and function of dendritic cells and contribution of these effects to tumour immune evasion. A pre-treatment in vitro model system was applied to study the effects of high HGF concentrations on the development of dendritic cells (DC) from monocytes. The effects of HGF on the phenotype of dendritic cell, functi

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5

Vasiliauskas, Juozas. "Hepatocyte Growth Factor-Like protein In prostate tumorigenesis." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1428070127.

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6

Zhou, Hongyan. "Hepatocyte growth factor-met signaling in ovarian cancer progression." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B36845346.

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7

Johansson, Conny M. "Biophysical characterisation of the hepatocyte growth factor-glycosaminoglycan interaction." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/9904.

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Glycosaminoglycans (GAGs) such as heparin, heparan sulfate (HS), chondroitin sulfate (CS) and dermatan sulfate (DS) are sulfated polysaccharides that exist on animal cell surfaces and in the extracellular matrix. GAGs are important in providing structural and hydrating support and interaction points for proteins of varied functions, for example growth factors and homeostasis regulatory proteins. Hepatocyte Growth Factor (HGF) is a protein growth factor that regulates cell growth, survival, proliferation, chemotaxis, cell morphology, tissue regeneration and angiogenesis. It is involved in embry

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8

Xu, Jianyu. "Mutations in the hepatocyte nuclear factor 1 and glucokinase genes in Southern Chinese patients with early-onset type 2 diabetes." Click to view the E-thesis via HKUTO, 2002. http://sunzi.lib.hku.hk/hkuto/record/B42576854.

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9

Holmes, Oliver. "Functional studies and protein engineering of hepatocyte growth factor/scatter factor." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604185.

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Signalling <i>via </i>the receptor Met, HGF/SF has multiple essential roles in development and the wound response of vertebrate organisms and can activate several pathways, leading to cell survival, cell proliferation, increased motility and invasion. The aim of my research was to investigate the function of individual domains of HGF/SF and to find protein fragments with good affinity for Met. Some of these fragments were then engineered based on structural information in order to produce an antagonist of HGF/SF-Met signalling. As this antagonist could be easily produced in protein form it cou

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10

McKinnon, Heather Joanne. "The role of hepatocyte growth factor/scatter factor in vascular remodelling." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625061.

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11

McCullough, Peter W. "Hepatocyte growth factor : Molecular Mechanisms of Colorectal Cancer Metastasis." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508939.

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12

Zhou, Hongyan, and 周紅艷. "Hepatocyte growth factor-met signaling in ovarian cancer progression." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B37937984.

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13

Dixon, Mark. "Signal transduction mechanisms involved in hepatocyte proliferation." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245710.

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14

Takeda, Yoshihisa. "Morphologic alteration of hepatocytes and sinusoidal endothelial cells in rat fatty liver during cold preservation and the protective effect of hepatocyte growth factor." Kyoto University, 1999. http://hdl.handle.net/2433/181710.

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15

Anilkumar, Thapasimuthu Vijayamma. "The pathobiology of hepatic stem cells (oval cells)." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244072.

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16

溫啟峰 and Kai-fung Wan. "Hepatocyte growth factor and met receptor signaling in nasopharyngeal carcinoma cell migration and invasion." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39557029.

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17

Bassett, David Ian. "Early patterning of the central nervous system in the zebrafish (Danio rerio)." Thesis, King's College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391709.

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18

Shen, Zan. "The kringle 1 domain of hepatocyte growth factor exerts both anti-angiogenic and anti-tumor cell effects on hepatocellular carcinoma." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40687661.

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19

Kishimoto, Yo. "Chronic vocal fold scar restoration with hepatocyte growth factor hydrogel." Kyoto University, 2011. http://hdl.handle.net/2433/142062.

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20

Marui, Akira. "Simultaneous application of basic fibroblast growth factor and hepatocyte growth factor to enhance the blood vessels formation." Kyoto University, 2005. http://hdl.handle.net/2433/144737.

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21

Spindler, Mark-Peter. "Transkriptionseinfluss einer Multiconsensusregion im 5'-flankierenden Genbereich des hepatocyte growth factor." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=968310206.

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22

Harrison, Phillip MacDonald. "Analysis of hepatocyte growth factor gene expression in fulminant hepatic failure." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266640.

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23

Xu, Jianyu, and 許健瑜. "Mutations in the hepatocyte nuclear factor 1 and glucokinase genes in Southern Chinese patients with early-onset type 2 diabetes." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B42576854.

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24

Hetzel, Simone Kerstin [Verfasser]. "Signaltransduktion der Wachstumsfaktoren Hepatocyte Growth Factor, Epidermal Growth Factor und Insulin-like Growth Factor-I in renalen proximalen Tubuluszellen des Kaninchens / Simone Hetzel." Ulm : Universität Ulm. Medizinische Fakultät, 2004. http://d-nb.info/1015438342/34.

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25

Naim, Ramin. "Koexpression von VEGF (Vascular endothelial growth factor), c-Met-Rezeptor und HGF/SF (Hepatocyte growth factor, scatter factor) in Pleurametastasen." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=962323403.

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26

Yant, Jeffrey James. "In vivo effects of hepatocyte growth factor/scatter factor on mouse mammary gland development." Thesis, Institute of Cancer Research (University Of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313536.

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27

Nagy, Janos. "Hepatocyte growth factor/scatter factor and C-met ligand-receptor in human breast cancer." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366258.

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28

Luo, Yi. "Mechanisms of epidermal growth factor receptor signalling in primary rat hepatocytes." Thesis, De Montfort University, 2009. http://hdl.handle.net/2086/2413.

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In the U.K. deaths due to liver diseases, especially alcohol related diseases, have risen considerably over the last 20 years. In 2005 up to 13,000 people died from liver related diseases within the U.K., including alcohol and viral liver failure and liver cancers. Worldwide hepatitis B affects about 2 billion people, killing 500,000 to 1 million per year. An effective way to treat liver disease is often liver surgery, such as liver resection for cancers and liver transplant for failure. However, the failure of liver regeneration by hepatocyte proliferation after resection surgery leads to a h

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29

Bradley, Lara. "Characterisation of the promoter region of the human gene for hepatocyte growth factor." Thesis, King's College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391770.

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30

Chen, Ketian. "Regulation of Human Bone Marrow-Derived Stem Cells by Hepatocyte Growth Factor." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/334.

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Bone formation and remodeling require continuous generation of osteoprogenitors from bone marrow stromal cells (MSC), which are regulated by local growth factors and hormones with putative roles in mesenchymal proliferation and differentiation. Hepatocyte growth factor (HGF) and its receptor c-Met are widely expressed in MSC and are thought to play a key role in the interactions between cells. 1,25-dihydroxyvitamin D (1,25OHD) is the most active metabolite of vitamin D. 1,25OHD binds to its nuclear/membrane vitamin D receptor (VDR) and generates appropriate biological responses. The purpose of

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31

Wheelhouse, Nicholas Mark. "The effect of amino acids on growth hormone action in ovine hepatocytes." Thesis, University of Aberdeen, 1999. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=185765.

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Many of the anabolic effects of growth hormone (GH) are indirect, occurring through GH-stimulated production of insulin-like growth factor-I (IGF-I) by the liver. As well as being GH regulated, plasma IGF-I concentrations have been demonstrated to be dependent upon protein nutrition, with low protein diets being associated with reduced plasma IGF-I concentrations. This effect cannot be reversed by GH, suggesting that liver sensitivity to GH is impaired. To investigate the mechanisms through which protein supply affects GH sensitivity, primary cultures of ovine hepatocytes were grown in defined

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32

Cheung, Man-ting, and 張敏婷. "Expression of met receptor tyrosine kinase in hepatocellularcarcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B4669965X.

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33

Naim, Ramin [Verfasser]. "Koexpression von VEGF (Vascular Endothelial Growth Factor), c-Met - Rezeptor und HGF/SF (Hepatocyte Growth Factor/ Scatter Factor) in Pleurametastasen / Ramin Naim." München : GRIN Verlag, 2007. http://d-nb.info/1181005078/34.

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34

Chellappa, Karthikeyani. "Functional analysis of Tyrosine residues in human hepatocyte nuclear factor 4alpha." Diss., UC access only, 2009. http://proquest.umi.com/pqdweb?index=72&did=1790348311&SrchMode=1&sid=1&Fmt=7&retrieveGroup=0&VType=PQD&VInst=PROD&RQT=309&VName=PQD&TS=1270229827&clientId=48051.

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Thesis (Ph. D.)--University of California, Riverside, 2009.<br>Includes abstract. Includes bibliographical references (leaves 293-348). Issued in print and online. Available via ProQuest Digital Dissertations.

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35

Voort, Robbert van der. "Hepatocyte growth factor, Met, and CD44 a ménage à trois in B cells /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/55874.

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36

Nagano, Tomokazu. "Beneficial effects of hepatocyte growth factor on animal models of acute renal failure." Kyoto University, 2003. http://hdl.handle.net/2433/148338.

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37

Ozeki, Makoto. "Preparation and evaluation of biodegradable hydrogel for controlled release of hepatocyte growth factor." 京都大学 (Kyoto University), 2005. http://hdl.handle.net/2433/144935.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(工学)<br>甲第11591号<br>工博第2537号<br>新制||工||1345(附属図書館)<br>23234<br>UT51-2005-D340<br>京都大学大学院工学研究科高分子化学専攻<br>(主査)教授田畑泰彦, 教授岩田博夫, 教授瀧川敏算<br>学位規則第4条第1項該当

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38

Bardelli, Alberto. "Identification of the transduction pathways mediating the cellular responses to the hepatocyte growth factor/scatter factor." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244059.

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39

Wang, Ye 1975. "The trafficking and signaling of EGF receptors in hepatocyte rafts /." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112318.

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Membrane rafts are small plasma membrane domains that contain high levels of cholesterol and sphingolipids. They have been implicated in processes as diverse as signal transduction, endocytosis and cholesterol trafficking. Traditional methods for the biochemical preparation of lipid rafts involve the extraction of membranes with nonionic detergents followed by the separation of a low-density, detergent-resistant membrane fraction on density gradients. Because of concerns regarding the possible introduction of artifacts through the use of detergents, several methods were developed for the isola

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40

Schwenger, Martin [Verfasser]. "Expression von Hepatocyte Growth Factor, Keratinocyte Growth Factor und der zugehörigen Rezeptoren im Verlauf der experimentellen chronischen Pankreatitis / Martin Stephan Schwenger." Kiel : Universitätsbibliothek Kiel, 2009. http://d-nb.info/1019868554/34.

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41

Peak, Matthew. "Control of glycogen synthesis by insulin and epidermal growth factor in hepatocytes." Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357813.

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42

Yang, Sin-Yu. "Prevascularization-free Primary Subcutaneous Transplantation of Xenogeneic Islets Co-encapsulated with Hepatocyte Growth Factor." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/264649.

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43

Williams, Matthew John. "Analysis of cellular mechanisms involved in scatter factor/hepatocyte growth factor-induced changes in cultured epithelial cells." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270439.

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44

Eleswarapu, Satyanarayana. "Mechanisms of Growth Hormone Regulation of Insulin-Like Growth Factor-I Gene Expression in Liver." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/37373.

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The overall objective of this research was to understand the mechanims by which growth hormone (GH) regulates insulin-like growth factor-I (IGF-I) gene expression in liver. Previous studies have suggested that GH regulation of IGF-I gene expression in liver is mediated by binding of the transcription factor signal transducer and activator of transcription (STAT) 5 to four binding sites located distantly from the IGF-I promoter. The first specific objective of this research was to determine whether additional STAT5 binding sites were involved in GH stimulation of IGF-I gene expression in liver.

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45

Nakano, Jota. "Effects of hepatocyte growth factor in myocarditis rats induced by immunization with porcine cardiac myosin." Kyoto University, 2014. http://hdl.handle.net/2433/193568.

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46

Ogino, Shuichi. "Efficacy of the dual controlled release of HGF and bFGF impregnated with a collagen/gelatin scaffold." Kyoto University, 2018. http://hdl.handle.net/2433/231010.

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47

Monvoisin, Arnaud. "Rôle du système urokinase/plasminogène et des métalloprotéases matricielles dans l'invasion des cellules du carcinome hépatocellulaire." Paris 7, 2001. http://www.theses.fr/2001PA077221.

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48

Aparicio, Thomas. "Carcinogenèse colorectale : implication des métalloprotéases matricielles, de l'hepatocyte growth factor et de la leptine." Paris 7, 2005. http://www.theses.fr/2005PA077125.

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49

Stubbs, Adam K. "Amino acid and growth hormone dependent regulation of insulin-like growth factor-I gene expression in ovine hepatocytes." Thesis, University of Aberdeen, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369135.

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This study was designed to assess the effects of amino acid supply and growth hormone (GH) treatment on IGF-I gene expression of ovine hepatocytes and to determine the possible mechanism(s) involved. Using a riboprobe that detect both type 1 and type 2 mRNA transcripts, GH and amino acid were shown to have separate and interactive effects on the regulation of IGF-I gene expression and these effects were similar for both transcripts. The stimulatory effects of GH and amino acid supply were shown to depend at least in part on transcriptional control, since transcription blockade resulted in the

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50

Ayubi, Nawid. "mRNA-Expression vom connective tissue growth factor (CTGF) und hepatocyt growth factor (HGF) nach laserinduzierter Thermotherapie (LITT) und chirurgischer Resektion experimenteller Lebermetastasen." [S.l.] : [s.n.], 2004. http://www.diss.fu-berlin.de/2004/183/index.html.

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