Relevant bibliographies by topics / Hepatocyte nuclear factor

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'Hepatocyte nuclear factor'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Hepatocyte nuclear factor"

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Eeckhoute, J. "Hepatocyte Nuclear Factor 4 enhances the Hepatocyte Nuclear Factor 1 -mediated activation of transcription." Nucleic Acids Research 32, no. 8 (April 28, 2004): 2586–93. http://dx.doi.org/10.1093/nar/gkh581.

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Sund, Newman J., Siew-Lan Ang, Sara Dutton Sackett, Wei Shen, Nathalie Daigle, Mark A. Magnuson та Klaus H. Kaestner. "Hepatocyte Nuclear Factor 3β (Foxa2) Is Dispensable for Maintaining the Differentiated State of the Adult Hepatocyte". Molecular and Cellular Biology 20, № 14 (15 липня 2000): 5175–83. http://dx.doi.org/10.1128/mcb.20.14.5175-5183.2000.

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ABSTRACT Liver-specific gene expression is controlled by a heterogeneous group of hepatocyte-enriched transcription factors. One of these, the winged helix transcription factor hepatocyte nuclear factor 3β (HNF3β or Foxa2) is essential for multiple stages of embryonic development. Recently, HNF3β has been shown to be an important regulator of other hepatocyte-enriched transcription factors as well as the expression of liver-specific structural genes. We have addressed the role of HNF3β in maintenance of the hepatocyte phenotype by inactivation ofHNF3β in the liver. Remarkably, adult mice lacki
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ULVILA, Johanna, Satu ARPIAINEN, Olavi PELKONEN, Kaoru AIDA, Tatsuya SUEYOSHI, Masahiko NEGISHI, and Jukka HAKKOLA. "Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I." Biochemical Journal 381, no. 3 (July 27, 2004): 887–94. http://dx.doi.org/10.1042/bj20040387.

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The cytochrome P4502a5 (Cyp2a5) gene is expressed principally in liver and olfactory mucosa. In the present study, the transcriptional mechanisms of hepatocyte-specific expression of Cyp2a5 were studied in mouse primary hepatocytes. The Cyp2a5 5′-flanking region −3033 to +10 was cloned in front of a luciferase reporter gene and transfected into hepatocytes. Deletion analysis revealed two major activating promoter regions localized at proximal 271 bp and at a more distal area from −3033 to −2014 bp. The proximal activation region was characterized further by DNase I footprinting, and a single c
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Wang, Zhongyan, та Peter A. Burke. "Hepatocyte nuclear factor-4α interacts with other hepatocyte nuclear factors in regulating transthyretin gene expression". FEBS Journal 277, № 19 (23 серпня 2010): 4066–75. http://dx.doi.org/10.1111/j.1742-4658.2010.07802.x.

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Gardner-Stephen, Dione A., та Peter I. Mackenzie. "Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4α". Pharmacogenetics and Genomics 17, № 1 (січень 2007): 25–36. http://dx.doi.org/10.1097/fpc.0b013e32801112b5.

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Khurana, Satish, Amit K. Jaiswal та Asok Mukhopadhyay. "Hepatocyte Nuclear Factor-4α Induces Transdifferentiation of Hematopoietic Cells into Hepatocytes". Journal of Biological Chemistry 285, № 7 (16 грудня 2009): 4725–31. http://dx.doi.org/10.1074/jbc.m109.058198.

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Tian, J. M., and U. Schibler. "Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4." Genes & Development 5, no. 12a (December 1, 1991): 2225–34. http://dx.doi.org/10.1101/gad.5.12a.2225.

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Aboudehen, Karam, Min Soo Kim, Matthew Mitsche, Kristina Garland, Norma Anderson, Lama Noureddine, Marco Pontoglio та ін. "Transcription Factor Hepatocyte Nuclear Factor–1βRegulates Renal Cholesterol Metabolism". Journal of the American Society of Nephrology 27, № 8 (28 грудня 2015): 2408–21. http://dx.doi.org/10.1681/asn.2015060607.

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Freedman, A. R., R. J. Sharma, G. J. Nabel, S. G. Emerson та G. E. Griffin. "Cellular distribution of nuclear factor κB binding activity in rat liver". Biochemical Journal 287, № 2 (15 жовтня 1992): 645–49. http://dx.doi.org/10.1042/bj2870645.

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The cellular localization of nuclear factor kappa B (NF-kappa B) binding activity in rat liver has been investigated using electrophoretic mobility shift assay on extracts of highly purified hepatocytes and Kupffer cells obtained from liver perfused in vivo with collagenase. Constitutive NF-kappa B binding activity was demonstrated in nuclear extracts of control Kupffer cells, and this was not apparently influenced by injection of lipopolysaccharide (LPS) into rats 24 h before perfusion. In contrast, little nuclear NF-kappa B binding activity was present in hepatocytes from control animals, al
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Tang, Hong, and Alan McLachlan. "Avian and Mammalian Hepadnaviruses Have Distinct Transcription Factor Requirements for Viral Replication." Journal of Virology 76, no. 15 (August 1, 2002): 7468–72. http://dx.doi.org/10.1128/jvi.76.15.7468-7472.2002.

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ABSTRACT Hepadnavirus replication occurs in hepatocytes in vivo and in hepatoma cell lines in cell culture. Hepatitis B virus (HBV) replication can occur in nonhepatoma cells when pregenomic RNA synthesis from viral DNA is activated by the expression of the nuclear hormone receptors hepatocyte nuclear factor 4 (HNF4) and the retinoid X receptor α (RXRα) plus peroxisome proliferator-activated receptor α (PPARα) heterodimer. Nuclear hormone receptor-dependent HBV replication is inhibited by hepatocyte nuclear factor 3 (HNF3). In contrast, HNF3 and HNF4 support duck hepatitis B virus (DHBV) repli
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Dissertations / Theses on the topic "Hepatocyte nuclear factor"

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Clissold, Rhian. "Identification of hepatocyte nuclear factor 1β-associated disease". Thesis, University of Exeter, 2017. http://hdl.handle.net/10871/31132.

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Heterozygous mutations and deletions of the gene that encodes the transcription factor hepatocyte nuclear factor 1β (HNF1B) are the commonest known monogenic cause of developmental kidney disease. However, diagnosis remains challenging due to phenotypic variability and frequent absence of a family history. There is also no consensus as to when HNF1B genetic testing should be performed. This thesis includes work looking at the identification of HNF1B-associated disease. An HNF1B score was developed in 2014 to help select appropriate patients for genetic testing. The aim in chapter 2 was to test
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Bingham, Coralie. "The renal manifestations of hepatocyte nuclear factor mutations." Thesis, University of Exeter, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269720.

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Hannoun, Zara. "Role of SUMO modification in hepatocyte differentiation." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5917.

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Primary human hepatocytes are a scarce resource with variable function, which diminishes with time in culture. As a consequence their use in tissue modelling and therapy is restricted. Human embryonic stem cells (hESCs) could provide a stable source of human tissue due to their properties of self-renewal and their ability to give rise to all three germ layers. hESCs have the potential to provide an unlimited supply of hepatic endoderm (HE) which could offer efficient tools for drug discovery, disease modelling and therapeutic applications. In order to create a suitable environment to enhance H
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Chéret, Claire. "Spécificité et redondance des facteurs de transcription HNF1α (Hepatocyte Nuclear Factor-1α) et HNF1β/vHNF1 (Hepatocyte Nuclear Factor-1β/variant HNF1) chez la souris". Paris 6, 2002. http://www.theses.fr/2002PA066076.

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Gresh, Lionel. "Rôles du facteur de transcription hepatocyte nuclear factor 1beta au cours de l'organogenèse." Paris 6, 2004. http://www.theses.fr/2004PA066143.

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Chellappa, Karthikeyani. "Functional analysis of Tyrosine residues in human hepatocyte nuclear factor 4alpha." Diss., UC access only, 2009. http://proquest.umi.com/pqdweb?index=72&did=1790348311&SrchMode=1&sid=1&Fmt=7&retrieveGroup=0&VType=PQD&VInst=PROD&RQT=309&VName=PQD&TS=1270229827&clientId=48051.

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Thesis (Ph. D.)--University of California, Riverside, 2009.<br>Includes abstract. Includes bibliographical references (leaves 293-348). Issued in print and online. Available via ProQuest Digital Dissertations.
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Marable, Sierra S. "The Role of Hepatocyte Nuclear Factor 4a in Renal Proximal Tubule Development." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595849621045508.

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Papachristodoulou, Maria. "A study of the ligand-binding properties of hepatocyte nuclear factor 4α (HNF4α)." Thesis, University of Surrey, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429895.

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Xu, Jianyu. "Mutations in the hepatocyte nuclear factor 1 and glucokinase genes in Southern Chinese patients with early-onset type 2 diabetes." Click to view the E-thesis via HKUTO, 2002. http://sunzi.lib.hku.hk/hkuto/record/B42576854.

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Karatza, Panagiota. "Characterization and functional analysis of the hepatocyte nuclear factor 1 alpha 5'-flanking region." Thesis, University of Leeds, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423198.

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Books on the topic "Hepatocyte nuclear factor"

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Bingham, Coralie. Hepatocyte nuclear factor-1B. Edited by Neil Turner. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0315_update_001.

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Hepatocyte nuclear factor-1B (HNF1B, also known as TCF2) is a transcription factor that is involved in renal development, and in the transcription of several genes implicated in other genetic renal diseases. Mutations in HNF1B cause maturity onset diabetes of the young, renal cysts and diabetes syndrome, and some cases of familial juvenile hyperuricaemic nephropathy. They also account for a large proportion of developmental renal disorders included abnormalities detected antenatally. The various abnormalities associated with the gene may occur in isolation or together in the same patient.
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Differential Induction of Nuclear Factor-κB and Activator Protein-1 Activity after CD40 Ligation Is Associated with Primary Human Hepatocyte Apoptosis or Intrahepatic Endothelial Cell Proliferation. Molecular Biology of the Cell, 2003.

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Book chapters on the topic "Hepatocyte nuclear factor"

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Stoffel, Markus. "The Role of the Hepatocyte Nuclear Factor Network in Glucose Homeostasis." In Molecular Basis of Pancreas Development and Function, 255–74. Boston, MA: Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1669-9_15.

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Shiota, Goshi, and Yoko Yoshida. "“Tet-On” System Toward Hepatic Differentiation of Human Mesenchymal Stem Cells by Hepatocyte Nuclear Factor." In Methods in Molecular Biology, 125–32. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-61779-468-1_11.

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Stoffel, M. "Role of the Hepatocyte Nuclear Factor Network in Maturity-Onset Diabetes of the Young (MODY)." In Frontiers in Diabetes, 251–64. Basel: KARGER, 2000. http://dx.doi.org/10.1159/000060928.

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Pinaire, Jane, Wan-Yin Chou, Mark Stewart, Katrina Dipple, and David Crabb. "Activity of the Human Aldehyde Dehydrogenase 2 Promoter Is Influenced by the Balance between Activation by Hepatocyte Nuclear Factor 4 and Repression by Perosixome Proliferator Activated Receptor δ, Chicken Ovalbumin Upstream Promoter-Transcription Factor, and Apolipoprotein Regulatory Protein-1." In Advances in Experimental Medicine and Biology, 115–21. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4735-8_14.

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Sladek, Frances M., and Shawn D. Seidel. "Hepatocyte Nuclear Factor 4α." In Nuclear Receptors and Genetic Disease, 309–61. Elsevier, 2001. http://dx.doi.org/10.1016/b978-012146160-7/50010-x.

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Bingham, Coralie. "Hepatocyte nuclear factor-1B." In Oxford Textbook of Clinical Nephrology, 2671–73. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0315.

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"HNF (hepatocyte nuclear factor)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics, 888. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_7711.

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"Hepatocyte nuclear factor-2." In Springer Reference Medizin, 1103. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_311774.

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Owen, K., G. Thanabalasingham, and AJ Juszczak. "MODY due to hepatocyte nuclear factor 4-alpha mutations (revision number 10)." In Diapedia. Diapedia.org, 2012. http://dx.doi.org/10.14496/dia.41040851228.10.

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Owen, K., G. Thanabalasingham, and AJ Juszczak. "MODY due to hepatocyte nuclear factor 4-alpha mutations (revision number 11)." In Diapedia. Diapedia.org, 2014. http://dx.doi.org/10.14496/dia.41040851228.11.

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Conference papers on the topic "Hepatocyte nuclear factor"

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Ning, Bei-Fang, Xin Zhang та Wei-Fen Xie. "Abstract 2463: Suppression of hepatocyte nuclear factor 4α by nuclear factor κB in hepatoma cells". У Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2463.

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Yamashita, Taro, Hikari Okada, Masao Honda, and Shuichi Kaneko. "Abstract 1904: Polyprenoic acid, the first-discovered hepatocyte nuclear factor 4 alpha agonist, inhibits multistep liver carcinogenesis." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1904.

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WANG, Zhu, and Franky Leung Chan. "Abstract 4576: Hepatocyte nuclear factor 4 alpha suppresses cell proliferation and induces cellular senescence and apoptosis in prostate cancer cells." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4576.

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Harrison, R. "HUMAN HEPATIC ENDOTHELIAL CELLS AND HEPATOCYTES IN CULTURE: MORPHOLOGICAL FEATURES, AND PRODUCTION OF VON WILLEBRAND FACTOR AND FIBRINOGEN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643350.

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Liver cells were derived from cadaveric organ donors. Pieces of human liver 5 to 50 grams were minced, washed, and incubated in collagenase at 37 degrees C. After washing, the cell suspension was plated into culture vessels that had been briefly pre-treated with an extract derived from human liver. A mixed population of liver cells, including endothelial cells, hepatocytes, and Kupffer cells, attached within hours. At the end of 2 to 3 weeks there developed clusters of densely packed cells of two types. The most numerous cells were initially fusiform but grew as a monolayer even when densely p
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Reports on the topic "Hepatocyte nuclear factor"

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Mirosevich, Janni. Investigating the Role of Hepatocyte Nuclear Factor-3 (HNF-3) Alpha and Beta in Prostate Cancer and Cellular Differentiation. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada455964.

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Mirosevich, Janni. Investigating the Role of Hepatocyte Nuclear Factor-3 (HNF-3) Alpha and Beta in Prostate Cancer and Cellular Differentiation. Fort Belvoir, VA: Defense Technical Information Center, January 2005. http://dx.doi.org/10.21236/ada431320.

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