Academic literature on the topic 'Hepatoprotective agent'

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Journal articles on the topic "Hepatoprotective agent"

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Meshack, Sanjana, and Suchita Gupta. "A Review of Plants with Remarkable Hepatoprotective Activity." Journal of Drug Delivery and Therapeutics 12, no. 1 (2022): 194–202. http://dx.doi.org/10.22270/jddt.v12i1.5283.

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Liver being vulnerable to exogenous substances makes disease associated with it a matter of worldwide concern. Several research thus focus on hepatoprotection .Preventive and therapeutic activity of plants as a hepatoprotective agent is a topic of interest for researchers. Hepatotoxic agents like carbon tetrachloride, paracetamol, isoniazide etc. increase the serum biomarkers of liver where ALT is more specific than AST in detecting liver injury. Drug-induced liver injury (DILI) wherein more than 900 drugs have been implicated in causing liver injury. Plant phenolics include simple phenols, ph
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Rizky, Muthiana, Herri S. Sastramihardja, and Ismet Muchtar Nur. "Solanumnigrum L. as a Hepatoprotective Agent." Althea Medical Journal 2, no. 1 (2015): 63–67. http://dx.doi.org/10.15850/amj.v2n1.433.

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Tanaka, Yoshitaka. "A new hepatoprotective agent, SY-640." Japanese Journal of Pharmacology 67 (1995): 46. http://dx.doi.org/10.1016/s0021-5198(19)46154-4.

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Vadivu, Rajendran, A. Jerad Suresh, K. Girinath, P. Boopathi Kannan, R. Vimala, and N. M. Satish Kumar. "Evaluation of Hepatoprotective and In-vitro Cytotoxic Activity of Leaves of Premna serratifolia Linn." Journal of Scientific Research 1, no. 1 (2008): 145–52. http://dx.doi.org/10.3329/jsr.v1i1.1046.

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Premna serratifolia is used by the traditional practitioners as cardiotonic, antibiotic, anti-coagulant, stomachic, carminative, hepatoprotective, antitumor etc. The present study aims in the evaluation of hepatoprotective and in-vitro cytotoxic activity of alcoholic extract of leaves of Premna serratifolia Linn. Hepatoprotective activity is studied by carbon tetrachloride induced hepato-toxicity in rats and the in-vitro cytotoxic activity is carried out by tryphane blue exclusion method using EAC cell lines. The degree of protection in hepatoprotective activity has been measured by using bioc
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ZHAO, X., A. MONTET та J. MONTET. "β muricholic acid: a new hepatoprotective agent☆". Journal of Nutritional Biochemistry 4, № 2 (1993): 105–12. http://dx.doi.org/10.1016/0955-2863(93)90008-k.

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Anand, K., B. Singh, D. Chand, and B. Chandan. "An Evaluation ofLawsonia albaExtract as Hepatoprotective Agent." Planta Medica 58, no. 01 (1992): 22–25. http://dx.doi.org/10.1055/s-2006-961382.

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Gomes, A., M. Das, P. Sur, et al. "Glycosmis arborea extract as a hepatoprotective agent." Phytotherapy Research 17, no. 5 (2003): 571–74. http://dx.doi.org/10.1002/ptr.1191.

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Heidari, Reza, Mohammad Reza Arabnezhad, Mohammad Mehdi Ommati, Negar Azarpira, Elham Ghodsimanesh, and Hossein Niknahad. "Boldine Supplementation Regulates Mitochondrial Function and Oxidative Stress in a Rat Model of Hepatotoxicity." Pharmaceutical Sciences 25, no. 1 (2019): 1–10. http://dx.doi.org/10.15171/ps.2019.1.

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Background: The xenobiotics-induced liver injury is a clinical complication. Hence, finding new hepatoprotective strategies has clinical value. Oxidative stress and its subsequent complications are major mechanisms involved in xenobiotics-induced hepatotoxicity. Boldine is one of the most potent antioxidant molecules widely investigated for its protective properties in different experimental models. In the current study, the hepatoprotective properties of boldine and its potential mechanisms of hepatoprotection have been investigated. Methods: Rats received thioacetamide (TAA; 200 mg/kg, i.p)
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Damle, Mrinalini C., Sachin V. Tembhurne, and Swapnil R. Todkar. "Evaluation of Hepatoprotective Activity of Hydroalcoholic Extract of Onion Peels Containing Protocatechuic Acid." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 82–88. http://dx.doi.org/10.22270/jddt.v9i4.2982.

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India is the second largest country for cultivation of onion. 19.90% of onion is cultivated in India. Onion that is Allium cepa family Amaryllidaceae used in daily diet for taste. Onions also have number of medicinal properties, such as hepatoprotection, anticancer, antifungal, antioxidant, antiulcer, anti-agging, anti-inflammatory, anticancer etc.[1-2] The dried scales or peels of onion also have the same medicinal constituents with same activity as raw onions. The onion peels contains flavonoids, such as anthocyanins, flavones (qurcertin and its derivatives), ferulic, Gallic, protocatechuic
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Lubis, Meiva Amelia, Aminah Dalimunthe, Panal Sitorus, and Denny Satria. "Hepatoprotective effects of ethanol extract of mobe leaves/eeml (artocarpus lacucha buch-ham.) against carbon tetrachloride induced hepatotoxicity in rats." International Journal of Ecophysiology 6, no. 2 (2024): 42–48. http://dx.doi.org/10.32734/ijoep.v6i2.17505.

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This study evaluates the protective effects of ethanol extract of mobe leaves (Artocarpus lacucha Buch-Ham.) on ALT, AST, and bilirubin levels in rats induced with carbon tetrachloride (CCl4) on Liver. The ethanol extract was prepared by maceration using 96% ethanol. Results showed that administering 400 mg/kg BW of the extract significantly reduced total bilirubin, ALT, and AST levels in CCl4-induced rats. Phytochemical screening revealed bioactive compounds like flavonoids, alkaloids, tannins, saponins, triterpenoids, and glycosides, which are potential antioxidants and hepatoprotective agen
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Books on the topic "Hepatoprotective agent"

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Malviya, Mr Rishabha, and Prof Pramod Kumar Sharma. Hepatoprotective Models and Natural Hepatoprotective Agent. Createspace Independent Publishing Platform, 2016.

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Book chapters on the topic "Hepatoprotective agent"

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Balamurugan, Jayapriya, and Lourdu Jafrin. "Screening Methods for the Evaluation of Hepatoprotective Agents." In Introduction to Basics of Pharmacology and Toxicology. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-5343-9_31.

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Chagoya de Sánchez, V., M. del Pilar Cabrales-Romero, and G. Velasco-Loyden. "An Adenosine Derivative Compound as a Hepatoprotective Agent." In Liver Pathophysiology. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-804274-8.00057-6.

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Shivashankara, Arnadi Ramachandrayya, Suresh Rao, Thomas George, et al. "Tea (Camellia sinensis L. Kuntze) as Hepatoprotective Agent." In Dietary Interventions in Liver Disease. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-814466-4.00015-x.

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Pandi, Vignesh, and Sam Johnson Udhayachandar. "Hepatoprotective Activity of Proline Derivatives." In Understanding Hepatotoxicity - Causes, Symptoms and Prevention [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1010711.

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The liver plays a dynamic role in detoxification, metabolic regulation, and maintaining physiological balance, yet it is highly prone to damage from drugs and toxic substances. Paracetamol overdose is a well-known cause of drug-induced liver injury (DILI), emphasizing the importance of finding effective protective compounds. Proline has shown promise in protecting the liver due to its antioxidant properties and ability to preserve mitochondrial function. This study inspects the liver-protective potential of a synthetic proline-based compound, 1-[(2-hydroxyanilino) acetyl] pyrrolidine-2-carboxy
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Siddiqui, Mohd Aftab, Mohammad Saidur Rahman, Anas Islam, Afreen Usmani, and Usama Ahmad. "Emodin: Anticancer Agent." In Frontiers in Clinical Drug Research - Anti-Cancer Agents. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815223910124090007.

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Cancer is a serious health issue that remains a significant cause of mortality around the world. Psychosocial support, surgery, radiation, and chemotherapy are common cancer treatments. However, because of the rising rate of cancer-related mortality and the adverse or toxic side effects of cancer chemotherapy and radiation therapy, new anticancer compounds obtained from nature, particularly plants, are currently being researched. Phytochemicals, which are naturally occurring plant substances, are important sources for new drugs and cancer treatment. Phytochemicals are selective in their action
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Anitha, S. "Micropropagation protocols for Phyllanthus amarus Schum. & Thonn." In Micropropagation of Medicinal Plants. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815196146124010007.

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Phyllanthus amarus Schum. & Thonn. is a medicinal plant belonging to the family Phyllanthaceae. It is used in Siddha, Homeopathy, Unani and Ayurvedic medicines. This plant is used for treating skin diseases, diabetes, fever, diarrhea, gastric problems and migraine. It also acts as an anticonvulsant, anti-inflammatory, analgesic, antiamnesic, antimicrobial, nephroprotective, antiviral, hepatoprotective, anticancer, and anti-atherosclerotic agent. It grows as a weed, but because of its high medicinal value, this plant was propagated in vitro, so as to meet the market demands and for rapid pr
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Shivashankara, Arnadi Ramachandrayya, Ashish Kumar, Rithin Ravi, et al. "Use of Tea (Camellia sinensis [L.] Kuntze) as a Hepatoprotective Agent in Geriatric Conditions." In Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-418680-4.00010-5.

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Singh, Nidhi, Veer Singh, and Mohan Prasad Singh. "In silico Interactions of the Biomolecules of Edible Mushrooms Against Lifestyle Diseases." In Mushrooms: A Wealth of Nutraceuticals and An Agent of Bioremediation. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080568123010009.

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Mushrooms are fungi that are consumed all over the world and contain bioactive nutritive components with nutritional and therapeutic qualities. Protein, minerals, vitamins and antioxidants are all found in edible mushrooms. Selenium, vitamin C, and choline are antioxidants that help the human body remove free radicals. Antimicrobial, antiviral, anticancer, anti-allergic, immunomodulation, anti-inflam.matory, anti-atherogenic, hypoglycemic, hepatoprotective, and antioxidant properties of mushrooms. Primary and secondary metabolites can be found in mushrooms. The primary metabolites are energy-p
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"Hepatoprotective Agents." In Ayurvedic Herbs. Routledge, 2012. http://dx.doi.org/10.4324/9780203049204-10.

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Singh, Priyanka. "Pharmacological Applications of Saffron (Crocus sativus)." In Ethnopharmacological Investigation of Indian Spices. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-2524-1.ch006.

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Saffron spice also known as Crocus sativus (Saffron crocus) belongs to the family of iridaceae. Many studies have proved its potential role in disease eradication. It has been reported to possess the attributes of a sedative, an anti-asthma, an emmenagogue, an expectorant, and an adaptogenic agent. Crocin, crocetin, and safranal are the most important biochemically active ingredients that were found in different parts of the plants in varying proportions like the peels, fruits, seeds, and rind of Crocus sativus. The in vitro and in vivo studies showed that saffron has got its therapeutic impli
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Conference papers on the topic "Hepatoprotective agent"

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El-Hennamy, Rehab E., Ayatollah A. El-Shorbagy, Rasha Salah Albeltagy, Medhat W. Shafaa, and Soad Nady. "THE IMMUNOTHERAPEUTIC EFFECT OF IL-22 VERSUS PRAZIQUANTEL TREATMENT AGAINST S.MANSONI –INDUCED LIVER FIBROSIS IN MICE." In Dubai International Conference on Research in Life-Science & Healthcare, 22-23 February 2024. Global Research & Development Services, 2024. http://dx.doi.org/10.20319/icrlsh.2024.2627.

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Background/Aim: Praziquantel (PZQ), the primary medication for schistosomiasis treatment, exhibits a potential resistance by the parasite. Therefore, the development of a new effective treatment is obligated. Interleukin-22 (IL-22) has been reported to have a hepatoprotective effect. The current study aimed to compare the effectiveness of IL-22 treatment versus PZQ against S. mansoni - induced liver fibrosis in mice. Materials and Methods: Forty male albino mice were divided into control, infected, IL-22 (0.36 µg/kg), and PZQ (a single dose of 600 mg/kg) groups. PZQ was administered alone or i
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Pogodaeva, P. S. "Changes in the biochemical parameters of the blood of rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-11-35-40.

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An interesting and unexplored to date is the hepatoprotective effect of hypoglycemic drugs, analogues of glucagon-like peptide-1, which include liraglutide. Knowing the positive effect of liraglutide on plasma lipid fractions and a general decrease in adipose tissue, a decrease in glucagon production and an increase in insulin synthesis, a beneficial effect on the cardiovascular system and an anti-inflammatory effect, there is reason to believe that this drug may be useful in the complex therapy of liver diseases, such as fatty hepatosis, cirrhosis and non-infectious hepatitis, as its action a
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Pogodaeva, P. S. "Changes in the parameters of a clinical blood test in rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-11-28-34.

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Glucagon-like peptide-1 is an isulin-like peptide hormone from the incretin family. The most popular pharmaceutical analogue of GLP-1 at the moment is liraglutide. GLP-1 receptors are localized in many areas of the brain responsible for the regulation of metabolic processes and eating behavior and in specific areas of the pancreas, heart, blood vessels, immune system, skin and adipose tissue, gastrointestinal tract and kidneys. We can definitely say that the effect of liraglutide extends to all tissues equipped with GLP-1 receptors, while the effect of the drug on the cardiovascular system, im
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Reports on the topic "Hepatoprotective agent"

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Zhu, Baoqiang, Xue Tao, Yuankui Wei, et al. The efficacy and safety of oral hepatoprotective agents combined with entecavir in the treatment of chronic hepatitis B: a network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.11.0024.

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