Log in

Relevant bibliographies by topics / Hepatoprotective properties / Journal articles

To see the other types of publications on this topic, follow the link: Hepatoprotective properties.

Journal articles on the topic 'Hepatoprotective properties'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Hepatoprotective properties.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Heidari, Reza, Mohammad Reza Arabnezhad, Mohammad Mehdi Ommati, Negar Azarpira, Elham Ghodsimanesh, and Hossein Niknahad. "Boldine Supplementation Regulates Mitochondrial Function and Oxidative Stress in a Rat Model of Hepatotoxicity." Pharmaceutical Sciences 25, no. 1 (2019): 1–10. http://dx.doi.org/10.15171/ps.2019.1.

Full text

Abstract:

Background: The xenobiotics-induced liver injury is a clinical complication. Hence, finding new hepatoprotective strategies has clinical value. Oxidative stress and its subsequent complications are major mechanisms involved in xenobiotics-induced hepatotoxicity. Boldine is one of the most potent antioxidant molecules widely investigated for its protective properties in different experimental models. In the current study, the hepatoprotective properties of boldine and its potential mechanisms of hepatoprotection have been investigated. Methods: Rats received thioacetamide (TAA; 200 mg/kg, i.p)

APA, Harvard, Vancouver, ISO, and other styles

2

Okovity, S. V., K. L. Raikhelson, A. V. Volnukhin, and D. A. Kudlai. "Hepatoprotective properties of glycyrrhizic acid." Experimental and Clinical Gastroenterology, no. 12 (December 23, 2020): 96–108. http://dx.doi.org/10.31146/1682-8658-ecg-184-12-96-108.

Full text

Abstract:

The review is devoted to the problem of treatment of non-alcoholic fatty liver disease, which is the most common pathology of the hepato-biliary system worldwide and is characterized by an increasing frequency, including of more severe forms. A wide range of pathogenetic relationships of non-alcoholic fatty liver disease with diseases of other organ systems, primarily with diseases of the cardiovascular system, type 2 diabetes mellitus, chronic kidney disease and diseases of the biliary tract, is presented. The main mechanisms of comorbidity are insulin resistance, oxidative stress, inflammati

APA, Harvard, Vancouver, ISO, and other styles

3

Heuman, Douglas M. "Hepatoprotective properties of ursodeoxycholic acid." Gastroenterology 104, no. 6 (1993): 1865–69. http://dx.doi.org/10.1016/0016-5085(93)90672-y.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Delgado-Montemayor, Cecilia, Paula Cordero-Pérez, Liliana Torres-González, et al. "Development of a Hepatoprotective Herbal Drug from Turnera diffusa." Evidence-Based Complementary and Alternative Medicine 2022 (January 10, 2022): 1–10. http://dx.doi.org/10.1155/2022/5114948.

Full text

Abstract:

The incidence of liver diseases, such as nonalcoholic fatty liver disease and drug-induced liver injury, continues to rise and is one of the leading causes of acute hepatitis. Current trends suggest that these types of conditions will increase in the coming years. There are few drugs available for the prevention or treatment of hepatic diseases, and there is a growing need for the development of safe hepatoprotective agents. The medicinal plant, Turnera diffusa, has many ethnopharmacological uses, one of which is the production of a flavonoid named hepatodamianol, which is the principal compon

APA, Harvard, Vancouver, ISO, and other styles

5

Damle, Mrinalini C., Sachin V. Tembhurne, and Swapnil R. Todkar. "Evaluation of Hepatoprotective Activity of Hydroalcoholic Extract of Onion Peels Containing Protocatechuic Acid." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 82–88. http://dx.doi.org/10.22270/jddt.v9i4.2982.

Full text

Abstract:

India is the second largest country for cultivation of onion. 19.90% of onion is cultivated in India. Onion that is Allium cepa family Amaryllidaceae used in daily diet for taste. Onions also have number of medicinal properties, such as hepatoprotection, anticancer, antifungal, antioxidant, antiulcer, anti-agging, anti-inflammatory, anticancer etc.[1-2] The dried scales or peels of onion also have the same medicinal constituents with same activity as raw onions. The onion peels contains flavonoids, such as anthocyanins, flavones (qurcertin and its derivatives), ferulic, Gallic, protocatechuic

APA, Harvard, Vancouver, ISO, and other styles

6

Lee, Ji-Eun, Da-Eun Jo, An-Jung Lee, et al. "Hepatoprotective and antineoplastic properties ofProtaetia brevitarsislarvae." Entomological Research 44, no. 6 (2014): 244–53. http://dx.doi.org/10.1111/1748-5967.12075.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Al-Tameemi, Zahraa Salam, Hany A. Al-Hussaniy, Ali Mahmoud Al-Samydai, Meena Akeel Naji, Fuaad I. Iraqi, and Fatima A. Naji. "A detailed analysis of Spirulina's therapeutic properties in liver protection, oxidative stress reduction, and cancer management." Current Issues in Pharmacy and Medical Sciences 38, no. 1 (2025): 27–30. https://doi.org/10.12923/cipms-2025-0004.

Full text

Abstract:

Spirulina, a cyanobacterium recognized for its nutritional benefits, has recently garnered attention for its potential therapeutic properties. This review aims to comprehensively consolidate current knowledge on the pharmacological attributes of Spirulina species, focusing on their hepatoprotective, antioxidant and anticancer effects. An exhaustive literature search was conducted, collating data from empirical studies, clinical trials and reviews pertaining to the pharmacological effects of Spirulina. Spirulina exhibits significant hepatoprotective activities, evidenced by its ability to mitig

APA, Harvard, Vancouver, ISO, and other styles

8

Tan, Shancai, Qiuxia Lu, Yueyue Shu, Yiran Sun, Fang Chen, and Lin Tang. "Iridoid Glycosides Fraction Isolated fromVeronica ciliataFisch. Protects against Acetaminophen-Induced Liver Injury in Mice." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/6106572.

Full text

Abstract:

Veronica ciliataFisch. has traditionally been used in Tibetan medicine for the treatment of hepatitis, cholecystitis, rheumatism, and urticaria. We analyzed the chemical composition of the iridoid glycosides fraction (IGF) isolated fromV. ciliataand evaluated the antioxidant and hepatoprotective properties. The IGF was separated by high-speed countercurrent chromatography (HSCCC) and the main compounds were identified by ultra-performance liquid chromatography coupled to a photodiode array. We determined the in vitro antioxidant ability of the IGF through radical scavenging assays and assessed

APA, Harvard, Vancouver, ISO, and other styles

9

Suponko, J. V., та N. I. Shtemenko. "Вплив нанопрепаратів кластерних сполук ренію на активність ферментів печінки в моделі пухлинного росту". Visnyk of Dnipropetrovsk University. Biology, medicine 1, № 2 (2010): 76–80. http://dx.doi.org/10.15421/021030.

Full text

Abstract:

Enzymes’ level in rat’s hepatocytes under Guerin's carcinoma T8 development as well as after injection of rhenium compounds and cis-platin has been studied. It has been determined that the decrease of enzymatic activity to the level of the animals of control group was observed at the simultaneous injection of cis-platin and cluster rhenium compounds in nanoliposomal and water-soluble forms. That confirms possible hepatoprotective properties of the rhenium compounds. It has been shown that hepatoprotective properties of rhenium cluster compounds mostly don’t depend on the form of their injectio

APA, Harvard, Vancouver, ISO, and other styles

10

Akhilesh, Singhai* Rajesh Gour** &. Sagar Singh Jough***. "HEPATOPROTECTIVE PROPERTIES OF HERBAL PLANTS: A REVIEW." International Journal of Scientific Research and Modern Education (IJSRME) 8, no. 1 (2023): 82–86. https://doi.org/10.5281/zenodo.8077164.

Full text

Abstract:

The body's many physiological functions depend on the liver, which is the most significant organ in this regard. The presence of inflammatory cells in the liver's tissue distinguishes hepatitis, an inflammation of the organ. kinds A, B, C, D, and E relate to the five basic kinds of viruses. The weight of disease and mortality is particularly concerning for these five categories. A serious health issue that affects the pharmaceutical business, drug regulatory organisations, and health care providers is liver damage or malfunction. For a very long time, liver illness has been treated usi

APA, Harvard, Vancouver, ISO, and other styles

11

Chakrabarty, Nishan, Hea-Jong Chung, Rashedul Alam, et al. "Chemico-Pharmacological Screening of the Methanol Extract of Gynura nepalensis D.C. Deciphered Promising Antioxidant and Hepatoprotective Potentials: Evidenced from in vitro, in vivo, and Computer-Aided Studies." Molecules 27, no. 11 (2022): 3474. http://dx.doi.org/10.3390/molecules27113474.

Full text

Abstract:

Gynura nepalensis D.C. (family: Asteraceae) has abundant uses in the alternative medicinal practice, and this species is commonly used in the treatment of diabetes, rheumatism, cuts or wounds, asthma, kidney stones, cough, urinary tract bleeding, gall bladder stones, hepatitis, diarrhea, hemorrhoids, constipation, vomiting, fertility problems, blood poisoning, septicemia, skin allergy, indigestion, high cholesterol levels, and so on. This study aims to investigate the hepatoprotective and antioxidant potential of the methanol extract of the Gynura nepalensis D.C. (GNME) along with chemical pro

APA, Harvard, Vancouver, ISO, and other styles

12

Bahmani, Mahmood, Hedayatollah Shirzad, Samira Rafieian, and Mahmoud Rafieian-Kopaei. "Silybum marianum: Beyond Hepatoprotection." Journal of Evidence-Based Complementary & Alternative Medicine 20, no. 4 (2015): 292–301. http://dx.doi.org/10.1177/2156587215571116.

Full text

Abstract:

Silybum marianum is a medicinal plant that has long been used as hepatoprotective remedy. It has been used for the treatment of numerous liver disorders characterized by functional impairment or degenerative necrosis. Its hepatoprotective activity is unique and acts in different ways, including antioxidant and anti-inflammatory activities, cell permeability regulator and membrane stabilizer, stimulation of liver regeneration and inhibition of deposition in collagen fibers, which may lead to cirrhosis. Most of documented data with Silybum marianum are about liver disorders; however, recently se

APA, Harvard, Vancouver, ISO, and other styles

13

Aslanian, Milena A., Larisa A. Bobrytska, Natalya L. Bereznyakova, et al. "Biochemical research of hepatoprotective activity of Lavaflam tablets in rats with subchronic hepatitis." Current Issues in Pharmacy and Medical Sciences 33, no. 1 (2020): 10–13. http://dx.doi.org/10.2478/cipms-2020-0003.

Full text

Abstract:

AbstractLiver damage is a common problem all over the world. To optimize the drug provision in the limited financing of the Health Care System, it is necessary to develop new drugs with hepatoprotective properties that are highly effective and of low cost. That is why we developed the original drug Lavaflam. Lavaflam is a combination of the following substances: dry concentrate of Helichrysum arenarium and Lavender oil. The purpose of the research was to assess the biochemical evidence of the hepatoprotective properties of the drug Lavaflam on the experimental model of subchronic hepatitis in

APA, Harvard, Vancouver, ISO, and other styles

14

Ratkin, Ye V., V. V. Ivanov, A. V. Ratkin, and V. S. Chuchalin. "Antioxidant and antiradical properties of polyphenols in the mechanism hepatoprotective actions of preparations Maackia amurensis." Bulletin of Siberian Medicine 10, no. 5 (2011): 91–94. http://dx.doi.org/10.20538/1682-0363-2011-5-91-94.

Full text

Abstract:

For finding-out of a role antioxidant and antiradical properties of poly-phenols in mechanisms hepatoprotective actions of preparations from Maackia amurensis activity of preparations from ядровой wood (Macsar), an extract of cellular culture Maackia amurensis, stilbens. Antiradical properties of preparations measured on ability to cooperate with difenilpikrilgidrazilom (DPPH). It is established, that for Macsar, PKMA, monomeasured and dimeric Stilbenes is absent correlations between antiradical activity of the given preparations from a polyphenolic complex Mauck Amur in modelling system with

APA, Harvard, Vancouver, ISO, and other styles

15

Mosa, O. F. "Embelin mitigates hepatotoxicity induced by isoniazid and rifampicin in rats." Ukrainian Biochemical Journal 96, no. 3 (2024): 48–56. http://dx.doi.org/10.15407/ubj96.03.048.

Full text

Abstract:

Isoniazid and rifampicin are reliable drugs against tuberculosis, but while effective, their use is associated with the risk of drug-induced liver damage. Embelin, a natural parabenzoquinone derived from the Embelia ribes plant, has gained attention for its potential therapeutic properties, antioxidant and organ-protective effects. The study aimed to assess the hepatoprotective properties of embelin against liver damage induced by isoniazid and rifampicin in rats. Wistar rats were used, and liver damage was induced by administration of isoniazid (100 mg/kg) and rifampicin (100 mg/kg). Embelin

APA, Harvard, Vancouver, ISO, and other styles

16

Indrajaya, Putra, Mudawamah Mudawamah, Umi Kalsum, Adinda Rizky Trisakti, and Aldin Akbar Rahmatullah. "Amelioration of Cigarette Smoke-Induced Hepatic Injury by Green Tea (Camellia sinensis) Extract: Evidence from SGOT and SGPT Biomarkers in a Murine Model." Journal of Basic Medical Veterinary 14, no. 1 (2025): 79–88. https://doi.org/10.20473/jbmv.v14i1.72636.

Full text

Abstract:

This study investigated the hepatoprotective effects of green tea extract (GTE) against cigarette smoke-induced liver damage in mice. Twenty-five male mice (Mus musculus) were divided into five groups: negative control (C-), positive control exposed to cigarette smoke (C+), and three experimental groups exposed to cigarette smoke and treated with different doses of GTE: 20 mg/kg BW (T1), 40 mg/kg BW (T2), and 60 mg/kg BW (T3). Following 36 days of treatment, serum SGOT and SGPT levels were measured as biomarkers of hepatocellular injury. Results showed significant elevation of both enzymes in

APA, Harvard, Vancouver, ISO, and other styles

17

Gyawali, Rajendra, Amita Shrestha, Ashma Khanal, et al. "HEPATOPROTECTIVE PROPERTIES OF SELECTED PLANTS AGAINST PARACETAMOL-INDUCED HEPATOTOXICITY IN MICE." Journal of Institute of Science and Technology 22, no. 1 (2017): 147–51. http://dx.doi.org/10.3126/jist.v22i1.17766.

Full text

Abstract:

The hepatoprotective properties of the ethanolic extracts of Punica granatum peels, Crataeva religiosa leaves and Jasminum polyanthrum leaves were evaluated for the paracetamol induced liver toxicity in mice. Antioxidant, cytotoxicity and phytochemical screening were carried out to assure the therapeutic efficacy of these plants. Oral administration of plant extracts for 7 days in mice significantly reduced the impact of paracetamol toxicity on the serum markers of liver damage, aspartate transaminase (AST), alanine transaminase (ALT) and total protein. The extract showed significant hepatopro

APA, Harvard, Vancouver, ISO, and other styles

18

Torshin, Ivan Yu, Olga A. Gromova, Olga V. Tikhonova, and Viktor G. Zgoda. "Hepatoprotective peptides of the drug Laennec." Experimental and Clinical Gastroenterology, no. 7 (October 7, 2022): 21–30. http://dx.doi.org/10.31146/1682-8658-ecg-203-7-21-30.

Full text

Abstract:

Human placenta hydrolysates (HPH) have a pronounced hepatoprotective effect, the molecular mechanisms of which are not well understood. As a result of de novo mass spectrometric sequencing and bioinformatics analysis of peptides, 27 peptides were found in the Laennec HPP preparation, which (1) support inositol phosphate-dependent signaling pathways of hepatocytes, (2) activate the target proteins RARA, AMPK, and (3) inhibit target proteins Notch1, GSK-3, PAK1 and TLR4. By exhibiting anti-inflammatory, antifibrotic, vasodilatory, antiatherosclerotic, and antidiabetic properties, these peptides

APA, Harvard, Vancouver, ISO, and other styles

19

Gupta, Purnendra Kumar, and Vivek Chourasia. "Pharmacological Investigations of Corchorus trilocularis and Cressa cretica Medicinal Plant for Hepatoprotective Activity." International Journal of Drug Delivery Technology 15, no. 02 (2025): 01–04. https://doi.org/10.25258/ijddt.15.2.43.

Full text

Abstract:

In albino rats that had been exposed to carbon tetrachloride-induced hepatotoxicity, the antioxidantand hepatoprotective properties of the ethanolic extract of Corchorus trilocularis and Cressa Cretica leaves were investigated. Biochemical markers such total protein (TP), total albumin (TA), serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphate enzyme (ALKP), whole blood levels, and bilirubin were estimated in order to determine the level of resistance. In vitro and in vivo lipid peroxidation generated by CCl4 was also inhibited by t

APA, Harvard, Vancouver, ISO, and other styles

20

Mihaylova, Rositsa, Reneta Gevrenova, Alexandra Stefanova, et al. "The Phytochemical Profiling, In Vitro Antioxidant, and Hepatoprotective Activity of Prenanthes purpurea L. and Caffeoylquinic Acids in Diclofenac-Induced Hepatotoxicity on HEP-G2 Cells." International Journal of Molecular Sciences 24, no. 18 (2023): 14148. http://dx.doi.org/10.3390/ijms241814148.

Full text

Abstract:

Oxidative stress is a common phenomenon of many liver disorders; it both affects patient survival and directly influences the applicability, effectiveness, and toxicity of drugs. In the pursuit of reliable natural remedies for hepatoprotection, this study reports on the complete phytochemical characterization, antioxidant, and hepatoprotective activities of the Prenanthes purpurea methanol-aqueous extract in an in vitro model of diclofenac-induced liver injury (DILI). An ultra high-performance liquid chromatography–high-resolution mass spectrometry analysis (UHPLC-HRMS) was conducted, delineat

APA, Harvard, Vancouver, ISO, and other styles

21

Khantal, Anjali, and Nidhi Bais. "In Vitro and In Vivo Studies on the extracts of Vitex Negundo and Hygrophilla Auriculata for their Hepatoprotective activity." Journal of Neonatal Surgery 14, no. 24S (2025): 221–30. https://doi.org/10.63682/jns.v14i24s.5927.

Full text

Abstract:

This study aimed to evaluate the hepatoprotective potential of aqueous and methanolic extracts of Vitex negundo and Hygrophila auriculata using in-vitro and in-vivo models. Phytochemical analysis revealed that V. negundo contains carbohydrates, glycosides, tannins, and saponins, while H. auriculata contains carbohydrates, alkaloids, glycosides, and proteins—compounds known for their therapeutic properties. Antioxidant activity was assessed using DPPH and Nitric Oxide radical inhibition assays. The methanolic extract of V. negundo demonstrated the strongest DPPH radical scavenging activity with

APA, Harvard, Vancouver, ISO, and other styles

22

MS, Mahesh, Santhosha DU, Manasa R, Vishwanath S, and Shekhara Naik R. "Hepatoprotective activity of Boerhaavia diffusa L." IP Journal of Nutrition, Metabolism and Health Science 3, no. 4 (2021): 109–13. http://dx.doi.org/10.18231/j.ijnmhs.2020.022.

Full text

Abstract:

is also known as Punarnava in Ayurveda, which is widely spread during warmer climate throughout the India and other countries. 6 species are available in India of which B. diffusa is one among them. In Ayurveda this plant is used for so many diseases like liver, kidney, heart, diseases. Also it cures different types of cancers caused by different mechanisms. It is also used as antimicrobial, it also deals with other properties. All these properties are due to different essential phytochemical components. Here in this review we have discussed, hepatoprotective activity property of developing pr

APA, Harvard, Vancouver, ISO, and other styles

23

K, Priyanka, Shankar Priyanka, Daniel Madhvi, and Deupa Hema. "A Review on the Nutritional and Hepatoprotective Properties of Madhuca indica Flower Extracts." International Journal of Environmental and Agriculture Research 11, no. 5 (2025): 64–71. https://doi.org/10.5281/zenodo.15552203.

Full text

Abstract:

<strong>Abstract</strong><strong>—</strong> Mahua (Madhuca indica), a member of the Sapotaceae family, is an important economic tree from India. Mahua flowers were rich in bioactive compounds such as carbohydrates, minerals- calcium,iron, antioxidants, flavonoids, and phenolic acids. Mahua flowers are nutritional and have medicinal properties. The paper reviews the Mahua flower's nutritional qualities and health-protective functions in the paracetamol-induced liver damage in the Wistar rat models. Traditional application records indicated that Mahua flowers have anti-inflammatory, antica

APA, Harvard, Vancouver, ISO, and other styles

24

Haretskaya, M. V., and V. M. Sheibak. "Hepatoprotective properties of taurine during carbon tetrachloride intoxication." Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 8, no. 4 (2014): 286–92. http://dx.doi.org/10.1134/s1990750814040039.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

GERMANÒ, M. P., R. SANOGO, C. COSTA, et al. "Hepatoprotective Properties in the Rat ofMitracarpus scaber(Rubiaceae)." Journal of Pharmacy and Pharmacology 51, no. 6 (1999): 729–34. http://dx.doi.org/10.1211/0022357991772871.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Lexa, Annette, Jacques Fleurentin, Paul Lehr, François Mortier, Marc Pruvost, and Jean-Marie Pelt. "Choleretic and Hepatoprotective Properties ofEupatorium cannabinumin the Rat." Planta Medica 55, no. 02 (1989): 127–32. http://dx.doi.org/10.1055/s-2006-961904.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Vafina, G. F., A. R. Uzbekov, T. A. Sapozhnikova, et al. "Hepatoprotective and Choleretic Properties of Levopimaric Acid Derivatives." Pharmaceutical Chemistry Journal 51, no. 5 (2017): 348–50. http://dx.doi.org/10.1007/s11094-017-1612-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Oshaghi, Ebrahim Abbasi, Iraj Khodadadi, Fatemeh Mirzaei, Mozafar Khazaei, Heidar Tavilani, and Mohammad Taghi Goodarzi. "Methanolic Extract of Dill Leaves Inhibits AGEs Formation and Shows Potential Hepatoprotective Effects in CCl4 Induced Liver Toxicity in Rat." Journal of Pharmaceutics 2017 (January 15, 2017): 1–9. http://dx.doi.org/10.1155/2017/6081374.

Full text

Abstract:

The research was aimed at evaluating the antiglycation, antioxidant, and hepatoprotective properties of methanolic extract of Anethum graveolens (dill). The antioxidant properties, photochemical characteristics, and antiglycation effects of dill extract were measured. Carbon tetrachloride-induced hepatotoxic rats were used to show the hepatoprotective activity of dill leaves. Different concentration of dill extract (0.032, 0.065, 0.125, 0.25, 0.5, and 1 mg/mL) showed potential antioxidant ability. The extract of dill leaves significantly reduced AGEs formation and also fructosamine and protein

APA, Harvard, Vancouver, ISO, and other styles

29

Odeyemi, Samuel, and John Dewar. "Repression of Acetaminophen-Induced Hepatotoxicity in HepG2 Cells by Polyphenolic Compounds from Lauridia tetragona (L.f.) R.H. Archer." Molecules 24, no. 11 (2019): 2118. http://dx.doi.org/10.3390/molecules24112118.

Full text

Abstract:

Lauridia tetragona (L.f) R.H. Archer is routinely used in traditional medicine; however, its hepatoprotective property is yet to be scientifically proven. To this effect, the hepatoprotective activity of the polyphenolic-rich fractions (PPRFs) was investigated against acetaminophen (APAP) injured HepG2 cells. The ability of the PPRF to scavenge free radicals was tested against 2,2-diphenyl-1-picrylhydrazyl (DPPH), and [2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonicacid)] (ABTS). The ferric ion reducing power (FRAP) was also evaluated as a cell-free antioxidant assay. The hepatoprotective ac

APA, Harvard, Vancouver, ISO, and other styles

30

Alam, Md Anzar, Barkati Md Tarique, Arvind Kumar, Raghavendara Kumar Sharma, Mohd Aleemuddin Quamri, and Khalid Eqbal. "Therapeutic Evaluation of Syrup Nexoliv™ for Liver Health Support." Journal of Drug Delivery and Therapeutics 15, no. 5 (2025): 123–31. https://doi.org/10.22270/jddt.v15i5.7121.

Full text

Abstract:

Background: Liver disorders, ranging from hepatitis to cirrhosis, are prevalent globally due to infections, toxins, and metabolic imbalances. Traditional medicine offers numerous herbal formulations known for their hepatoprotective properties. Syrup NexolivTM is a polyherbal formulation composed of 23 medicinal plants traditionally recognized for liver protection, detoxification, and overall hepatobiliary support. This study evaluates the hepatoprotective potential of Syrup Nexoliv (SN) based on its rich phytoconstituents. Objective: To assess the hepatoprotective effect of Syrup Nexoliv throu

APA, Harvard, Vancouver, ISO, and other styles

31

Singh, Upma, Pankaj Singh, Pradeep Kumar Singh, Shikha Shukla, Ram Lakhan Singh, and Sukanta Mondal. "Evaluation of antioxidant potential, DNA damage and hepatoprotective properties of Lagenaria siceraria plant against acetaminophen induced hepatotoxicity." Functional Foods in Health and Disease 13, no. 3 (2023): 117. http://dx.doi.org/10.31989/ffhd.v13i3.1072.

Full text

Abstract:

Introduction: Lagenaria siceraria has various pharmacological effects like antioxidant, anti-hyperglycemic, anti-ulcer, anti-cancer, hepatoprotective, antimicrobial, anti-hyperlipidemic, anti-inflammatory and cardioprotective activities and is used to treat various diseases like diabetes, jaundice, piles, ulcers, hypertension, colitis, insanity, and skin diseases.Context and purpose of the study: The aim of the present study was to evaluate the phytochemical content, antioxidant activity, DNA damage and hepatoprotective activities of Lagenaria siceraria (LS)plant’s parts to explore their nutra

APA, Harvard, Vancouver, ISO, and other styles

32

Chuchalin, V. S., A. V. Ratkin, Ye V. Ratkin, S. A. Fedoreyev та V. P. Bulgakov. "Effect of polyphenolic complexes wood and cellular culture Maackia amurensis on the MR тomography performance of a liver". Bulletin of Siberian Medicine 10, № 3 (2011): 145–48. http://dx.doi.org/10.20538/1682-0363-2011-3-145-148.

Full text

Abstract:

Comparative evaluation of hepatoprotective properties of polyphenolic fraction from wood (Maksar) and a polyphenolic complex of cell culture of Maakia amurensis.Therapeutic efficacy of the objects was assessed by their effect on the MR tomographic performance of the liver of rats with experimental СCl4-hepatitis. Hepatoprotective activity of polyphenol complex cell culture Maakia amurensis is not inferior to the original effect of the drug Maksar.

APA, Harvard, Vancouver, ISO, and other styles

33

Timasheva, G. V., E. F. Repina, D. O. Karimov, et al. "PECULIARITIES OF METABOLIC CHANGES IN EXPERIMENTAL ANIMALS AT EARLY TERMS OF PHARMACOLOGICAL CORRECTION OF TOXIC LIVER DISEASES." Toxicological Review, no. 1 (February 24, 2020): 13–19. http://dx.doi.org/10.36946/0869-7922-2020-1-13-19.

Full text

Abstract:

The paper presents the results of studies on metabolic changes in experimental animals with acute tetrachloromethane poisoning and further damage correction using substances possessing hepatoprotective properties: oxymethyluracil, ademethionine and ethylmethylhydroxypyridine succinate. It has been revealed that oxymethyluracil exhibits heteroprotective properties at the earliest stages of acute toxic liver damage with chemical toxicants: it has membrane-stabilizing properties, normalizes the levels of antioxidant system parameters, thereby restoring the oxidative-antioxidant balance in hepatoc

APA, Harvard, Vancouver, ISO, and other styles

34

Ketova, E. S., E. Yu Bibik, A. V. Myazina, and S. G. Krivokolysko. "Role of potential biotargets of new cyanothioacetamide derivatives in substantiating the identified hepatoprotective activity." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 3 (June 10, 2025): 23–26. https://doi.org/10.33920/med-13-2503-04.

Full text

Abstract:

The widespread prevalence of liver diseases in the modern world entails the need to use existing medications and search for new drugs with hepatoprotective properties. Metabolic disorders associated with obesity, hyperglycemia, and hyper lipidemia are often a consequence or cause of damage to the hepatobiliary system. It is relevant to search for and substantiate the mechanism of action of new agents that have a positive impact on carbohydrate and lipid metabolism while simultaneously having hepatoprotective effects. Purpose. To evaluate the role of potential biotargets of new cyanothioacetami

APA, Harvard, Vancouver, ISO, and other styles

35

Min, Jianbin, Hao Chen, Zipeng Gong, et al. "Pharmacokinetic and Pharmacodynamic Properties of Rosmarinic Acid in Rat Cholestatic Liver Injury." Molecules 23, no. 9 (2018): 2287. http://dx.doi.org/10.3390/molecules23092287.

Full text

Abstract:

The objective of this study was to evaluate the hepatoprotective and metabolic effects of rosmarinic acid (RA) in rats. RA [100 mg/kg body weight (BW)] was intragastrically (i.g.) administered to Sprague-Dawley (SD) rats once a day for seven consecutive days. The rats were then i.g. administered α-naphthylisothiocyanate (ANIT) (80 mg/kg once on the 5th day) to induce acute intrahepatic cholestasis after the last administration of RA. Blood samples were collected at different time points (0.083 h, 0.17 h, 0.33 h, 0.5 h, 0.75 h, 1 h, 1.5 h, 3 h, 4 h, 6 h, 8 h, 12 h, 20 h) after administration, a

APA, Harvard, Vancouver, ISO, and other styles

36

Chuchalin, V. S., A. V. Ratkin, Ye V. Ratkin, et al. "Role of stilbens in mechanisms hepatoprotective properties of polyphenols Maackia amurensis." Bulletin of Siberian Medicine 9, no. 3 (2010): 101–5. http://dx.doi.org/10.20538/1682-0363-2010-3-101-105.

Full text

Abstract:

For finding-out of a role monomer and dimer srilbens in realization hepatoprotective properties of polyphenols maakia amurensis activity of polyphenolic complexes from wood (Maksar), an extract of cellular culture maakia amurensis, and also monomer and dimer srilbens, allocated of a substance Maksar was investigated.Therapeutic efficiency of researched objects was estimated on their influence on survival rate of animals, morphological and biochemical parameters of a liver and wheys of blood of rats with an experimental СCl4-hepatites. It was established, that hepatoprotective influence of Maks

APA, Harvard, Vancouver, ISO, and other styles

37

Garg, Deepak, Amit Sharma, Pragi, and Varun Kumar. "Evaluation of the hepatoprotective and nephroprotective properties of bael fruit extract against carbon tetrachloride-induced toxicity in rats." Journal of Applied Pharmaceutical Research 12, no. 3 (2024): 11–20. http://dx.doi.org/10.69857/joapr.v12i3.524.

Full text

Abstract:

Background: Bael is well-known for its antibacterial properties. Aqueous fruit extracts have also been shown to have hepatoprotective properties; the nephroprotective and hepatoprotective properties of Ethanolic extracts have not yet been tested. Objective: To evaluate the hepatoprotective and nephroprotective activities of Bael against CCl4-induced toxicity in rats. Methods: Two dosages of Bael's Ethanolic extract (100 and 200 mg/kg/day) were compared with 100 mg/kg of silymarin. Histopathologic alterations of the liver and kidney, as well as biochemical blood parameters such as bilirubin, ur

APA, Harvard, Vancouver, ISO, and other styles

38

Mahadevan, S.1 Muhammed Uvais T. T.2 Abdul Rahman S.3 Shamina S.*4 Jamal Fathima M.5. "A Review on Therapeutic Properties and Hepatoprotective Activities of Traditional Medicinal Plants: Andrographis paniculata, Azadirachta indica, Terminalia arjuna, and Picrorhiza kurroa." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 3200–3213. https://doi.org/10.5281/zenodo.15111118.

Full text

Abstract:

Liver diseases are a global health concern, necessitating the search for effective hepatoprotective agents. Medicinal plants like Andrographis paniculata, Azadirachta indica, Terminalia arjuna, and Picrorhiza kurroa, have been traditionally utilized for their medicinal and therapeutic benefits, particularly in liver protection. This review explores the hepatoprotective activities in medicinal plants, focus on active phytochemicals and potential mechanisms of action. Key bioactive compounds, including arjunolic acid, azadirachtin, and picrosides, have demonstrated anti-inflammatory, antioxidant

APA, Harvard, Vancouver, ISO, and other styles

39

Buko, V., I. Kuzmitskaya, S. Kirko, et al. "Betulin attenuated liver damage by prevention of hepatic mitochondrial dysfunction in rats with alcoholic steatohepatitis." Physiology International 106, no. 4 (2019): 323–34. http://dx.doi.org/10.1556/2060.106.2019.26.

Full text

Abstract:

Betulin, a pentacyclic triterpene, possesses antioxidant, anti-inflammatory and hepatoprotective properties. The aim of this study was to evaluate the impact of liver mitochondria in hepatoprotection of betulin using a rat model of alcoholic steatohepatitis induced by ethanol administration (4 g/kg, intragastric) for 8 weeks. The treatment with betulin (50 and 100 mg/kg b.w., intragastric) during this period attenuated the histological signs of steatohepatitis and lowered the serum and liver triglyceride contents, as well as the serum activities of aspartate aminotransferase, alanine aminotran

APA, Harvard, Vancouver, ISO, and other styles

40

Bagali, Rajkumar S., Sunil S. Jalalpure, Sachin D. Shinde, Ganesh R. Pawar, Gajanan S. Sanap, and Shitalkumar S. Patil. "EVALUATION OF IN VITRO ANTIOXIDANT AND IN VIVO HEPATOPROTECTIVE ACTIVITY OF BAUHINIA VARIEGATA ROOT ETHANOLIC EXTRACT AGAINST CCL4 INDUCED LIVER INJURY IN RATS." INDIAN DRUGS 58, no. 11 (2021): 60–65. http://dx.doi.org/10.53879/id.58.11.12859.

Full text

Abstract:

Plant derived herbal formulations and remedies provide an effective means for the treatment of various types of disease that are dogmatic and incurable in other types of systems of medicines, but it is essential to explore and establish the scientific basis for therapeutic action of herbal plant medicines. Bauhinia variegata root ethanolic extract was studied for the hepatoprotective activity against CCl4 induced liver injury in rats. For estimation of hepatoprotective role of B. variegata, total bilirubin count, serum enzymes level and finally histopathological study of liver were performed.

APA, Harvard, Vancouver, ISO, and other styles

41

Agu, KingsleyChukwunonso, SilvanusOlu Innih, and GeraldIkechi Eze. "Immunomodulatory and hepatoprotective properties of Solanum torvum (Turkey berry)." Sahel Medical Journal 21, no. 1 (2018): 13. http://dx.doi.org/10.4103/1118-8561.232777.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Herasymets, I., L. Fira, and I. Medvid. "Study of the Reishi mushrooms dry extract hepatoprotective properties." Ukrainian biopharmaceutical journal, no. 4(61) (November 19, 2019): 28–34. http://dx.doi.org/10.24959/ubphj.19.232.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

BODAKHE, Surendra H., and Alpana RAM. "Hepatoprotective Properties of Bauhinia variegata Bark Extract." YAKUGAKU ZASSHI 127, no. 9 (2007): 1503–7. http://dx.doi.org/10.1248/yakushi.127.1503.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Abdulkhakova, G. V., E. Zh Komilov, M. I. Asrarov, and N. A. Ergashev. "HEPATOPROTECTIVE PROPERTIES OF HEXAGALLOYL-GLUCOSE AND HEPTAGALLOYL-GLUCOSE TANNINS." Научное обозрение. Биологические науки (Scientific Review. Biological Sciences), no. 2 2025 (2025): 58–63. https://doi.org/10.17513/srbs.1407.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

T., Lilis, Saharnauli Janna verawaty Simorangkir, and Okto P. E. Marpaung. "Virgin Coconut Oil (VCO) Attenuates Hepatotoxicity Induced by Cigarette Smoke in Rats." Majalah Obat Tradisional 28, no. 1 (2023): 54. http://dx.doi.org/10.22146/mot.82659.

Full text

Abstract:

Researchers have connected the antioxidants in virgin coconut oil (VCO) to the growing health benefits; however, little is known about the hepatoprotective and antioxidant properties of VCO against oxidative stress and liver damage brought on by smoking cigarettes. The research examined the hepatoprotective and antioxidant properties of VCO against oxidative stress and liver damage. Male Wistar rats were split into 4 groups: Group 1 (the control group) was fed rat pellets; Group 2 (the control positive group) was fed the basic diet and exposed to cigarette smoke; Group 3 was fed the basic diet

APA, Harvard, Vancouver, ISO, and other styles

46

Wibowo, Much Ilham Novalisa Aji, Nur Aeni, Zidna Mazayatul Huda, and Nunuk Aries Nurulita. "The Hepatoprotective Effect of Ethanol Extract of Syzygium campanulatum (Korth) and Syzygium aromaticum (L) Leaf on Male Wistar Rat (Rattus Norvegicus) was Induced by Paracetamol." JURNAL ILMU KEFARMASIAN INDONESIA 15, no. 2 (2017): 196. http://dx.doi.org/10.35814/jifi.v15i2.517.

Full text

Abstract:

Syzygium campanulatum and Syzygium aromaticum contains antioxidant components suchas flavonoids, phenolic, and terpenoids. May have hepatoprotective properties in reducing SGPT and SGOT activity. This research wants to determine the potency of hepatoprotective of ethanolic extract of Syzygium campanulatum (Korth) and Syzygium aromaticum leaf compared with curcuma tablets. This research uses 24 male Wistar rats divided into 6 groups: I, II, III (as a normal, induction, and compared control), group IV, V, VI were treated 105, 210, and 420 mg/kg BW respectively. The study was conducted for 9 days

APA, Harvard, Vancouver, ISO, and other styles

47

Venmathi Maran, Balu Alagar, Mohammad Iqbal, Prakash Gangadaran, Byeong-Cheol Ahn, Pasupuleti Visweswara Rao, and Muhammad Dawood Shah. "Hepatoprotective Potential of Malaysian Medicinal Plants: A Review on Phytochemicals, Oxidative Stress, and Antioxidant Mechanisms." Molecules 27, no. 5 (2022): 1533. http://dx.doi.org/10.3390/molecules27051533.

Full text

Abstract:

Hepatotoxicity is a major global public health concern. Despite advances in modern medicine, the demerits of chemically prepared drugs outweigh their merits. In addition, the treatment of liver diseases based on modern medical principles has been found to produce several undesired side effects. Therefore, the exploration of medicinal plants has gained worldwide attention for treating various diseases, including liver diseases, owing to their potential efficacy and cost effectiveness. Several plants, including Andrographis paniculata, Bauhinia purpurea, Commelina nudiflora, Dillenia suffruticos

APA, Harvard, Vancouver, ISO, and other styles

48

Sun, Yiran, Qiuxia Lu, Libo He, et al. "Active Fragment ofVeronica ciliataFisch. Attenuates t-BHP-Induced Oxidative Stress Injury in HepG2 Cells through Antioxidant and Antiapoptosis Activities." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/4727151.

Full text

Abstract:

Excessive amounts of reactive oxygen species (ROS) in the body are a key factor in the development of hepatopathies such as hepatitis. The aim of this study was to assess the antioxidation effect in vitro and hepatoprotective activity of the active fragment ofVeronica ciliataFisch. (VCAF). Antioxidant assays (DPPH, superoxide, and hydroxyl radicals scavenging) were conducted, and hepatoprotective effects through the application oftert-butyl hydroperoxide- (t-BHP-) induced oxidative stress injury in HepG2 cells were evaluated. VCAF had high phenolic and flavonoid contents and strong antioxidant

APA, Harvard, Vancouver, ISO, and other styles

49

LIMA, Izabela Rangel, Ivanise Brito SILVA, Roberta M. Leite LIMA, Tainá M. Santos SILVA, Maria B. Sousa MAIA, and Sônia Pereira LEITE. "HEPATOPROTECTIVE EFFICACY OF METHANOLIC EXTRACT OF INDIGOFERA SUFFRUTICOSA (MILL) ON PARACETAMOL-INDUCED LIVER DAMAGE IN MICE." Arquivos de Gastroenterologia 56, no. 4 (2019): 333–38. http://dx.doi.org/10.1590/s0004-2803.201900000-62.

Full text

Abstract:

ABSTRACT BACKGROUND: Indigofera suffruticosa Mill (Fabaceae) is abundant in northeastern Brazil and popularly used in the treatment of infectious and inflammatory processes. Several biological properties, such as anti-inflammatory, anticancer, antitumor, hepatoprotective and low toxicity, are reported for this plant. OBJECTIVE: This study investigated hepatoprotective activity and the antioxidant effect of methanolic extract of I. suffruticosa leaves (MEIS) on Swiss albino mice submitted to experimental models of acetaminophen-induced liver injury. METHODS: MEIS (50 mg/kg; p.o.) was standardiz

APA, Harvard, Vancouver, ISO, and other styles

50

Jenila Jose Jancy V, Kalaichelvan V, and Balakrishnan N. "Hepatoprotective Activity of Cassia Auriculata against Carbon Tetrachloride-Induced Hepatotoxicity in Rats." International Journal of Research in Pharmaceutical Sciences 12, no. 1 (2021): 594–601. http://dx.doi.org/10.26452/ijrps.v12i1.4125.

Full text

Abstract:

In previous decade the herbal drugs have been investigated for their medicinal properties for the natural therapy. About half of the people around the world, even in the developed countries had been using the medicinal plants and natural drugs as treatment of diseases. In this regard the herbs should also be investigated for their pharmacological properties, safety concerns and efficacy too. In the present investigation, we have believed medicine and inhibiting potential effects of extract of C. auriculata was investigated for the hepatoprotective activity. This study facilitated to rediscover

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!