Dissertations / Theses on the topic 'Herbal cosmetics'

El siguiente proyecto de investigación tiene como finalidad determinar si es rentable la implementación de una planta de elaboración de crema corporal hidratante a base de camu camu y de jalea real. Hoy en día el mercado del cuidado personal ya no es sólo cuestión de cuidar la imagen sino también la salud, es por eso que en el presente es uno de los negocios más rentables.
The main objective of the following research is to determine the successful of installing a factory of a hydrating body lotion of Camu camu and Royal jelly. Nowadays, the hygiene and personal care market is one of the most rentable business because the more someone invest in this topic the better personal image in a healthy body they will have.
Trabajo de investigación

El presente trabajo desarrolla el plan de exportación de lociones corporales a base de insumos de la biodiversidad peruana, particularmente aceite de sacha inchi orgánico, teniendo como destino la ciudad de Bogotá en Colombia, a través de la constitución de la empresa productora y comercializadora BIOPERÚ NATURAL PRODUCTS S.A.
This work develops an exportation plan of body lotion to Bogota, Colombia, based in raw materials from the Peruvian biodiversity, such as the sacha Inchi organic plant. This business will trade this product througgh BIOPERU NATURAL PRODUCTS S.A.C. Company.
Trabajo de investigación

2016 - 2017
This project is addressed to the definition of the chemical profile of selected PGI products of Campania region and related byproducts to highlight the presence of phytochemicals with health benefits. The species studied were Corylus avellana cultivar “Nocciola di Giffoni” and Castanea sativa cultivar “Marrone di Roccadaspide” PGI products of Campania region. The phytochemical investigation on C.avellana cultivar ‘Tonda di Giffoni’ byproducts allowed us to isolate and characterize, by 1D and 2D NMR experiments, 22 new cyclized diarylheptanoids and diaryletherheptanoids, some of which highly hydroxylated, named giffonins A-V. Cyclized diarylheptanoids were characterized by a C-C bond among the C-1 and C-2 positions of the two aromatic rings, while cyclized diaryletherheptanoids were characterized by an ether linkage among the C-1 and C-17 of the two aromatic moieties. Some of isolated giffonins and the MeOH extracts displayed the ability to prevent oxidative damages of human plasma lipids, induced by H2O2 and H2O2/Fe2+. Moreover, a metabolomic study of “green” extracts of C.avellana leaves was carried out. 1H NMR experiments of “green” extracts were performed and the metabolite variation among different extracts was further evaluated multivariate data analysis. Food and Drug Administration has recognized hazelnut as “heart-healthy” food, in onder to highlight the compounds responsible of this property, a detailed characterization of the lipids occurring in fresh and roasted “Tonda di Giffoni” hazelnut was performed by LC-ESI/LTQOrbitrap/MS/MSn. LC-MS analysis has showed a wide range of compounds from oxylipins and long chain bases to phospholipids, sphingolipids, and glycolipids. Thereby, at the best of our knowledge, this is the first report of many of these metabolites in hazelnut kernels. With the aim to achieve deeper insight into the chemical composition of Castanea sativa Mill., source of the Italian PGI product “Marrone di Roccadaspide”, the phytochemical investigation of the leaves has been carried out; the phenolic compounds isolated were quantified by LC-ESI(QqQ)MS. Moreover, the ability of isolated compounds to protect HaCaT human keratinocytes from UVB-induced damage has been investigated. during the PhD stage at the University of Veterinary and Pharmaceutical Sciences, preliminarity tests to evaluate the ability of C.sativa and C.avellana extracts to inhibit in vitro reactive oxygen species formation and NF-κB activation. To explain the strong antioxidant activity of MeOH extract of C.sativa shells, his metabolic profile LC-ESI/LTQOrbitrap/MS/MSn was carried out. LC-MS led the identification a wide range of compounds belonging to the different chemical classes such as tannins, in particular hydrolysable tannins, ellagitannins derivatives and condensed tannins; moreover the HPLC analysis was carried out; the structure of isolated compounds were elucidated by NMR and their quantitative determination was carried out by LC-ESI(QqQ)MS. [edited by auhtor]
XVI n.s.

碩士
嘉南藥理科技大學
化妝品科技研究所
98
According to the previous dowments, many Chinese herbs are with skin thera peutic benefits. In recent years, the cosmetic products with Chinese herbs active ingredients have been a kind of tendency. Because Asiaw attach importance to skin whitening, whitening cosmetic products have a lot of requirement in ASIA market. This experiment used many kinds of Chinese medicinal herb, including Momordica charantia L., Nelumbo nucifera G., Nymphaea lotus L., Angelica sinensis D., Salvia miltiorrhiza B. etc.. We evaluated the extraction by antioxidation test, inhibition tyrosinase activity assay, MTT assay and so on. Next step, we chose the strong activty of extraction to add in whitening cosmetics. We evaluated the whitening cosmetic by in vivo. On the anti-oxidation tests, ABTS free radical scavenging ability of Nymphaea lotus L. showed SC50 was 0.0025 mg/mL, its better than Trolox. DPPH free radical scavenging ability showed the SC50 of Nymphaea lotus L. was 0.0067 mg/mL, and the SC50 of Trolox was 0.0045 mg/mL. Inhibition tyrosinase activity assay, the IC50 of Nymphaea lotus L. and Nelumbo nucifera G. mixture was 0.11 mg/mL. And the results show that add Vit C and Morus alba L. appropriately, can increase inhibition tyrosinase acitivity of Nelumbo nucifera G., Namely, whitening compound herbal extracts for inhibition tyrosinase activity, are better than the original single-whitening herbal extracts inhibit the effect more good. Apply the Chinese medicinal herb with whitening activity on the emulsion formula to perform skin nature appraisal and the skin chromatic aberration appraisal. Finally it demonstrated that the whitening can improve whitening effect. The emulsion B (active constituent increase Nymphaea lotus L, Nelumbo nucifera G.), not only had whitening effect but also color spot, the pore, the primary purple nature, the ultraviolet ray color spot can keep improvement after overall skin inspection . In the future, the Chinese medicine herb will have well develop in whitening and Multiple - effects cosmetic products.

碩士
嘉南藥理大學
化粧品應用與管理系
106
In this study, five species of Taiwan herbal plants, including Dichondra micrantha, Desmodium triflorum, Euphorbia hirta, Anisomeles indica, Artemisia princeps var. orientalis, were extracted and used as cosmetic ingredients. Hara plants were harvested and divided into two parts, stems and leaves. Therefore, six samples of herbal plants were extracted by used the heat reflux extraction and then. The extracts were analyzed by anti-MMPs zymography for anti-aging investigation, anti-hyaluronidase zymography for anti-allergy test, and disc diffusion method for anti-bacterial assay. According to the experimental results, the effective samples were selected and mixed into three combined extraction solutions (designated as A5, B4, and C1). Research data showed that three multiple herbal extraction combination (A5, B4, and C1) have marked functions of inhibiting both matrix metalloproteinases (MMP-9 or MMP-2) and hyaluronidase to prevent collagen fibers and hyaluronic acids, present in the dermal extracellular matrix, from their degradation. Finally, the best anti-aging and anti-allergy extract combinations were added to the anti-wrinkle creams further used for the safety and efficiency evaluation of cosmetics on the upper arm skin of volunteer subjects. The patch testing results showed that one of ten volunteer subjects (10%) had a weak positive reaction (a rash), and the other nine volunteer subjects (90%) had negative irritant reactions for 96 h. These results confirmed that three multiple herbal extraction creams (A5, B4, and C1) were safe cosmetics that would not cause skin irritation. On the other hand, 15 volunteer subjects used multiple herbal extraction creams (A5, B4, and C1) and evenly applied to the face for one month. According to the anti-wrinkle efficiency evaluation testing results, the A5, B4, and C1 creams showed 40% (two of five volunteer subjects), 60% (three of five volunteer subjects), and 60% (three of five volunteer subjects) improvements, respectively. In short, according to the results presented in this study, the multiple herbal extracts exhibited anti-aging and anti-allergy capacities in vitro, as well as these multiple herbal extraction creams with the anti-wrinkle effects were also proven effective in vivo.

碩士
嘉南藥理科技大學
化妝品科技研究所
98
According to previously studies, the major microorganism which can cause axillary malodor is Corynebacterium and Cycas revolute Thunb, Paeoniae Lactiflorae Radix, Rheum palmatum, Polygoni Cuspidati Rhizoma provide markedly antimicrobial effects. In addition some studies indicated that chitosan exhibited greatly antimicrobial ability. In this study, distilled water, methanol, 50% and 95% ethanol were used for extracting Chinese herbal medicine by different extraction methods. these Chinese herbal medicine extracts and chitosan were performed antibacterial analysis by disc agar diffusion test. Finally proportional mix them for estimating synergistic antibacterial effect. The results showed that 0.5% chitosan, inhibition zone 20.0 mm, and methanol extracted Cycas revolute Thunb, inhibition zone 20.0 mm, own the most noticeable antimicrobial effect; the next is ethanol extracted Cycas revolute Thunb, inhibition zone 18.0 mm. Nevertheless, those mixtures failed in synergistic antibacterial effect that cannot reach to the same antimicrobial effect with single extraction, the reason may be caused by constituents interaction. There could be more studies in the future. The present commercial antiperspirants are composite of chemical ingredients; due to some related research displayed that they could be potential harm to human bodies, and sensitization of skin, we expect to develop natural malodor inhibitors which are more safety and harmless for human, hope they could be much important for related application.

碩士
嘉南藥理科技大學
化妝品科技研究所
98
Previous studies reported that the matrix metalloproteinases (matrix metalloproteinases, MMPs) play an important role both in addition to the maintenance of normal physiological function and the pathogenesis of many diseases. Because MMPs can be broken down collagen, elastin and other extracellular matrix, they may be involved in the process of skin aging. In this study, we selected the alcohol extracts from thirty-four kinds of Chinese herbal medicines, and analyzed MMPs activity secerted from mouse 3T3 fibroblasts by gelatin-based zymography. We found that the alcohol extracts of Panax ginseng、Angelica sinensis、Spilanthes acmella、Cucurbita moschata could inhibit the activity of MMP-2 significantly, and the alcohol extracts of Aquilaria malaccensis、Androraphis paniculata decreased the activity of MMP-9 significantly. Because MMP-2 is able to damage collagens Ⅰ and Ⅲ, and MMP-9 can destory collagen IV, we consider that the alcohol extract of P. ginseng, A. sinensis, S. acmella, C. moschata, A. malaccensis, A. paniculata have intensive anti-aging effects and they can be applied in anti-aging skin care products. On the other hand, we found that alcohol extracts of 14 kinds of Chinese herbal medicines (Arctium lappa, Aquilaria malaccensis, Nelumbo nucifera, Andrographis paniculata, Aenthum graveolens、Nelumbo nucifera, Lonicera japonica, Agrimonia pilosa, Tribulus ierrestris, Crataegus pinnatifida, Ginkgo biloba, Lilium lancifolium, Diospyros kali, Hedyotis diffusa) were tested by MTT assay and the results showed the phenomenon of cell proliferation. These Chinese herbal medicine extracts can be used in cosmetics for cell activation.

MENVSC
Department of Hydrology and Water Resources
Africa is endowed with various earthy materials, of which each community is uniquely identified. Inspite of the vast knowledge of western cosmetics, application of traditionally used cosmetics have been in existence and will be into practice from generation to generation, this is as a result of their various indigenous knowledge about traditional cosmetics. They are mostly applied during traditional rites and festive periods. Occasionally, earthy materials play a vital role in traditionally used cosmetics. Different reasons have been associated with the use of these earthy materials, they are: for skin cleansing, protection against ultra violet radiation, skin lightening, perfecting the distorted part of the skin and improving beauty. This study is focused on the physico-chemical, chemical and mineralogical characterisation of earthy materials indigenously used as cosmetics. This is achieved firstly by identifying the various earthy materials applied topically as well as their constituents. Samples for this study were obtained from six (6) different African countries namely: Botswana, Cameroon, Democratic Republic of the Congo, Nigeria, South Africa and Swaziland and were subjected to the following analyses: Scanning Electron Microscope and Electron Dispersive X-ray Spectroscopy for the morphology and elemental analysis, hydrometer method for the determination of particle sizes of each sample and a texture Auto Lookup Software Package (TAL Version 4.2) for the classification of their various textures (%clay, %sand and %silt). The X-ray diffractometry was applied for the identification of their mineral phases (secondary, major and minor). The Brunauer Emmett and Teller (BET) method was used for the physisorption analysis and classifying them according to their isotherm types (Type I, II, III, IV, V and VI). The chemical analysis was achieved by X-ray fluorescence (XRF). The result revealed that the morphology of the various representative samples varies, except CMR 1; 2, SCC 1; 2 and SLW 1; 2 which showed same structure and same elemental constituents, their resemblance indicated that they possess same geological formation. The XRF result indicated the presence of the following trace elements: Al, As, Au, Ba, Bi, Br, Ca, Cd, Ce, Cl, Co, Cr, Cs, Dy, Er, Eu, Fe, Ga, Gd, Ge, Hf, Hg, Ho, I, In, K, La, Lr, Lu, Mg, Mn, Mo, Na, Nd, Ni, Nb, Os, P, Pb, Pd, Pr, Pt, Re, Rh, Ru, S, Sc, Se, Sb, Si, Sm, Sn, Sr, Ta, Te, Tb, Th, Ti, U, V, W, Y, Yb, Zr and Zn, were measured in ppm. For example, Fe – 66.47 (Qwa-Qwa), Al – 4.64 (Swaziland), Si – 6.26 (Democratic Republic of Congo), Ti – 3.75 (Qwa-Qwa) and so on. From the particle size distribution analysis, some samples were identified to be clay (BTS 1, BTS 2, NG 1, SCC 4, SCC 5, SCC 9, SCC 11, SCC 12, SWL 1 and SWL 2) with their particle sizes < 2μm, whereas other samples showed other properties which are > 2 μm. Ten minerals were identified in the clay fraction samples: albite, goethite, halloysite, hematite, kaolinite (kaolinite-1Md, kaolinite 1) Mica (muscovite), sulphur, talc, chalcanthite and whewellite. The BET method vii for physical adsorption revealed that BTS 1, BTS 2, CMR 1, CMR 2, DRC A, DRC B, NG 1, NG 2, SWL 1, SWL 2, SCC 1, SCC 4, SCC 5, SCC 8, SCC 9, SCC 11 and SCC 12 countries possess Type II isotherm whereas samples from SCC 2, SCC 6, SCC 7 and SCC 10 had Type III isotherm. The physisorption analysis result also determined the various surface areas and porosity of each representative samples.

碩士
中原大學
生物醫學工程研究所
104
Artificial antibacterial agents (such as Methyl Peraben(M.P.) and Propyl Paraben(P.P.)) were important factor in causing skin allergies and skin irritation. Therefore, searching for alternatives and decreases of the artificial antibacterial agents have become a major issue in cosmetics industry. The interactions between antibiotic medicines and plant components have already been investigated by domestic and foreign scholars. Nonetheless, there isn’t relevant reports that relative to interactions between artificial agents in cosmetics and the extracts of Chinese herbal. This study evaluates the in-vitro interactions (synergism, addition effect, antagonism ) between methanol extracts of Pogostemon cablin, Almond acid and two kinds of common ingredients used in cosmetics, against Escherichia coli and Propionibacterium acne. The results of this study were expected that as a reference of type and that dose for adding antibacterial agents in cosmetics and Chinese herbals in order to reduce damage to human skin. In this study, we extracted Pogostemon cablin with methanol, then practiced respectively the alone and one-on-one combined Antibacterial Susceptibility Testing (AST) of four kinds of reagents (Pogostemon cablin, almond acid, M.P. and P.P.) of vary concentrations (0.1 %, 1.0 %, 2.0 % and so on) with the Disk-diffusion method, and at last assessed the interactions between these four reagents with the Combination Index (CI). The results of this study showed that Pogostemon cablin possessed good synergism or addition effects when it was combined respectively with Almond acid, M.P. and P.P.. This means that the formula amounts of M.P. and P.P. can be reduced and substituted by the increased using of Pogostemon cablin extracts and Almond acid in cosmetics, and the overall antibacterial ability of cosmetics could still be able to maintain. In addition to assess for anti-pimples of cosmetics in dose study that Almond acid which is commonly used could be replaced by adding more ingredients of Pogostemon cablin, and the best combination formula is 1.0 % Pogostemon cablin to 0.1 % Almond acid. As for the components of combined artificial antibacterial agents, M.P. and P.P., this study indicated that there is obvious antibacterial synergism while combining these two artificial antibacterial agents. Thus, even without the addition of Chinese herbal extracts; the original amount of M.P. and P.P. can be moderately reduced.

Thesis (M.Tech.: Food Technology)-Dept. of Biotechnology, Durban University of Technology, 2007 xv, 122 leaves
Several herbs are well known for their nutritional applications. The reported study tested some herbs for their efficacy as antioxidants. The herbs and combinations thereof were analyzed for antioxidant activity using two comparative methods: the beta-carotene bleaching method and through measurement by the Rancimat apparatus. The efficacy of the antioxidants was also tested in a cosmetic base cream. The concentration of the natural antioxidant vitamins, such as vitamin C, vitamin E and beta-carotene was determined by analytical methods. The methods used for analysis provided adequate results for interpretation. All herbs exhibited antioxidant activity, at comparable levels. The two methods used for analysis showed variable results, as previous researchers have shown. In terms of antioxidant potency, the herbs were ranked as follows: fenugreek > coriander > oregano > sage (beta-carotene bleaching method), oregano > sage > coriander > fenugreek (Rancimat method). Oregano and sage were good synergists, when combinations of herbs were used. Fenugreek, unlike the other herbs under investigation, is a prooxidant when used at higher concentrations. A direct relationship was observed between the concentration of herbs and antioxidant potency for sage, oregano and coriander. Fenugreek which is prooxidant at higher concentrations, should be used as an antioxidant independently rather than a synergist. This was the most important finding in the reported study. Similar antioxidant activities of the herbs were observed in the base cosmetic formulation. The reported study has provided an adequate base for further quantitative research into the innovative topic of antioxidants.

Master of Commerce In the discipline of MARKETING In the SCHOOL OF ECONOMIC AND BUSINESS SCIENCES At the UNIVERSITY OF THE WITWATERSRAND,2016
In today’s knowledge society, the promotion of herbal products and the subsequent consumer purchase of herbal products has been on the rise recently. This is mostly attributed to the growing believe that organic or natural products are safer to use and promote a health life style. In the same vein, the understanding of consumer motivations, attitudes and the purchase behaviour of herbal cosmetics purchase has attracted attention worldwide from both academicians and business practioners – especially marketing managers in the herbal cosmetic industry. The current study is one of the few studies in African context to investigate the predictors of consumer purchase intentions of herbal cosmetics in South Africa. This study sought to examine the effects of social influence, perceived benefits of herbal cosmetics on consumer attitude towards herbal cosmetics and their purchase intention. In total seven hypotheses were postulated and to empirically test these hypotheses a data set of 246 collected from Generation Y female cohort at the University of the Witwatersrand was used for the purpose. A structural equation modelling approach using AMOS 23 statistical software was used to empirically test the proposed seven hypotheses using the collected data set. The research findings supported all the proposed hypotheses in a significant way except one hypothesis H5 (eco-literacy and purchase intention relationship) which although positive - was insignificant. However, the results also indicated that eco-literacy has a significant influence on purchase intention via its effects on consumer attitude towards herbal cosmetics. Based on the current study findings, both academic and practical managerial contributions are made. On the academic front, new literature on a rarely researched subject of herbal cosmetics purchase intention predictors - in an oftenmost neglected research context – Africa context is generated. On the managerial front, recommendations on the possible strategies that can be adopted by marketing managers in the herbal cosmetic industry are provided based on the research findings. Finally, future research avenues are also proposed.
XL2019

Ο προσδιορισμός του προφίλ των καταναλωτών ομοιοπαθητικών φαρμάκων και φυτικών καλλυντικών. Να προσδιορίσουμε ειδικότερα τα δημογραφικά και ψυχογραφικά χαρακτηριστικά τους, όπως το φύλο τους, την ηλικία τους, την οικογενειακή τους κατάσταση, το επάγγελμά τους, την αγοραστική τους συμπεριφορά, την κουλτούρα τους, την προσωπικότητά τους, να εντοπίσουμε τις ομάδες αναφοράς τους και να διαπιστώσουμε ποιοος ο βαθμός ικανοποιήσής τους από τη χρήση αυτών των προϊόντων.
The determination of the profile of consumers of homeopathic medicines and herbal cosmetics.More particularly to identify demographic and psychographic characteristics such as gender,age, marital status, profession, their purchasing behavior, their culture, their personality, to identify the reference groups and to ascertain what is the degree of satisfaction with the use of these products.

碩士
嘉南藥理科技大學
化妝品科技研究所
98
The emergence of cosmetics provides us an access to prevention of aging and maintenance of youthfulness. Based on consumers functional demanding in cosmetics as well as the expectation of multiple effects from one single product, such as moisturizing, whitening, anti-aging, and sunscreen, nowadays the ingredients tend to be more complicated and multiple. The adoption of natural materials has inevitably become one of the key factors in cosmetics development. In the previous documents and literature concerning herbs, a lot of Chinese herbal medicines and natural products made of animals possess the functions to prevent or cure skin diseases and sunscreen, as well as an increase of the nutrition of dermal. Moreover, they contribute to mend the deficiencies of skin, such as drying, mottling, acnes, and wrinkles. Also, they can strengthen the elasticity of skin, reduce the keratosis pilaris in dermal and pigmentation, and prevent the sebum function from degenerating. Therefore, the application of Chinese herbal medicines to cosmetics has been viewed as a current in a nature-oriented world. As a matter of fact, composition or addition of Chinese herbal medicines to cosmetics has taken the lead in modern society, and its wide usage in cosmetology has also been prevailing worldwide. Though there is a lot of written information about Chinese herbal medicines cosmetology in ancient Chinese medicine records, its toxicity has not been closely examined yet. Traditionally, cosmetics safety evaluations are primarily conducted on animals and human bodies. However, animal welfare groups criticize these deeds as inhuman so that researchers decide to substitute cell levels for animals and human bodies. Therefore, in this study, I intend to conduct a cytotoxicity test to evaluate the possible toxicity existing in Chinese herbal medicines with cosmetology effects. By so doing, I wish to establish a complete and fast safety evaluation model system on Chinese herbal medicines. In this study, we see that in vitro cytotoxicity test, MTT reduction assay mixes sixty-six kinds of Chinese herbal medicines of different concentrations (100, 50, 10, 1μg/mL) with Mus musculus fibroblast cell line (L929) for twenty-four hours, then it marks IC50=100 μg/mL as critical value to determine the degree of cytotoxicity. The result indicates that the values of IC50 in Acanthopanax gracilistylus, Artemisia apiacea, Artemisia argyi, Astragalus mongholic, Atractylodes macroce, Bupleurum chinense, Cinnamomum cassia, Cinnamomum cassia, Curcuma longa, Curcuma zedoaria, Cynanchum atratum, Cyperus rotundus, Ephedra sinica, Glycyrrhiza uralensis, Ligustrum lucidum, Lithospermum erythrorhizon, Magnolia officinals, Perilla frutescens, Salvia miltiorrhiza, Schizandra chinensis, Sophora flavescens, Taraxacum mongolicum and Zingiber officinale are all less than 100 μg/mL, which suggests that they all contain cytotoxicity. On the other hand, Neutral red uptake (NRU) assay mixes six kinds of Chinese herbal medicines of different concentrations (100, 50, 10, 1μg/mL) with L929 cells for twenty-four hours, then it marks IC50=100μg/mL as critical value to determine the degree of cytotoxicity. The outcome shows that the values of IC50 in Houttuynia cordata and Zingiber officinale are both less than 100 μg/mL, which suggests that they both contain cytotoxicity. In vivo dermal primary irritation test, patch test reveals that the PII (primary irritation index) in Houttuynia cordata and Zingiber officinale are 0.8±1.1, 0.6±0.9 respectively, which fall in the slight irritation category. For the correlation of in vitro and in vivo test, Neutral red uptake assay (R=-0.915) presents far more accurately than MTT reduction assay (R=-0.461) in judging the correlation of toxicity and irritation of Chinese herbal medicines. Therefore, we can take Neutral red uptake assay of cytotoxicity as a first priority to judge whether certain Chinese herbal medicines contain toxicity or not, which may well ensure effectiveness and quickness and meet the request of humanity.

碩士
亞洲大學
保健營養生技學系碩士班
101
Our country's first monograph of herbalism "Shen Nong's Herbal Classic" clearly indicate a cosmetic effect of 63 kinds of Chinese medicine. Sui Chao Yuan Fang Zhu treat patients, "annexed to the" health guidance law on the records of massage and beauty. Tang after the 《emergency preparedness daughter to party》《 Herbal 》《Diet Herbal 》《 Eat a meal 》《 With the interest rate home food spectrum》and so documented a variety of beauty, the beauty of Chinese medicine has excellent long and rich connotations. This study analyzes published by the Committee on Chinese Medicine and Pharmacy, Department of Health in the Republic a hundred years in June [beauty among the classics of Traditional Chinese Medicine literature analysis (Chang, 2011) in ancient Chinese medicine information collected, in which the beauty of Chinese herbal medicines such items up to 384 pens, the beauty in Chinese medicines for up to 28 categories described in the vocabulary of the beauty and efficacy of up to 818. 384 pen of Chinese herbal medicines information in accordance with "drug class", "gas", "weird", "Meridian", "effectiveness" field to compile information on the form and coding, the use of statistical methods to analyze the drug classification "gas", and "flavors", "Meridian" and "cosmetic effect" correlation between the pairwise results. The correlation analysis using the SPSS statistical software, the relevant comparison. The Chinese medicine herbal theory of the four gas, flavors, Meridian and summarized the effectiveness of the role of traditional Chinese medicine, this study for analysis using the wisdom of ancient Chinese medicine, the use of statistical methods and analyzed the relationship of potency and efficacy of 384 pen beauty of traditional Chinese medicines, traditional Chinese medicine. The findings provide further scientific experimental research in the modern study of beauty in Chinese medicines, and forecast the strength of the effectiveness of traditional Chinese medicine in the role of beauty

碩士
國立海洋大學
食品科學系
91
The objectives of the study are to explore the efficacy of an anti-aging and whitening cosmetics that containing different extracts of Chinese herbal remedies composed of Cerviparvum cornu, Asparagi radix, Ligustici rhizoma, Armeniacae semen, Asiasari radix, Atractylodis rhizoma, Angelicaedahuricae radix, Ampelopsis radix, Aconiticoreani tuber with different solvents. The study includes 1. To evaluate the efficacy of anti-aging and whitening of the extracts of Chinese herbal remedies by observation the scavenging capacity of DPPH radical and tyrosinase inhibition via determining cells viability, collagen formation of the cultured fibroblast, and melanin inhibity of the cultured melanocyte, 2. To prepare and characterize the gel products containing different extracts of Chinese herbal remedies. The characteristics of gel products studied including storage stability, water holding capacity, skin elasticity, skin whitening and safety test. The results obtained are: Scavenging effects for DPPH radical and tyrosinase inhibition effect increased with increasing the concentration of the extracts of Chinese herbal remedies. Water, 50% ethanol, 95% ethanol extracts showed more than 50% scavenging effects for DPPH free radical (5 mg/ml), the 95% ethanol extracts had the highest scavenging effect among them whereas the water extracts of Chinese herbal remedies had the highest tyrosinase inhibitory activity than the other two extracts. It showed 56.3% tyrosinase inhibitory activity at 1 mg/ml and 72.6% tyrosinase inhibitory activity at 10 mg/ml. Cell viability results showed the extracts concentration between 2-1000 μg/ml with different solvents showed no significant different on STO and WS1 viability. The 50% ethanol and 95% ethanol extracts at concentrations higher than 250 μg/ml inhibited B16 viability, however the 95% ethanol extracts enhanced STO and WS1 proliferation after cultured for 48 hr. The 50% ethanol extracts resulted in 230% enhancement on STO proliferation after cultured for 72 hr. Chinese herbal remedies extracts enhanced higher collagen formation of WS1 than that of the control (no Chinese herbal remedies extracts) after growth for 24 or 48 hr. Chinese herbal remedies extracts with different solvents elevated twice the collagen content on STO (2-1000 μg/ml) than that of the control. Chinese herbal remedies extracts revealed 60% inhibition on melanin content of B16 at concentration ≦250 μg/ml and 50~70% inhibition on melanin content of A 375 at 8 μg/ml. The stabilities of cosmetic product containing with or without Chinese herbal remedies extracts were stable for sonication (135 W, 42KHz, 5 min), for centrifuging (3000 rpm, 30 min), and for more than four months high temperature (50℃) storage. The pH of gel products did not change significantly. These results showed that gel product had good stability. pH of gel products containing different concentrations of Chinese herbal remedies extracts are between 4.8-6.0. The safety test resulted in no erythema based on the Daize score test. Water holding capacity in terms of electrical capacitance ratio were higher for those containing Chinese herbal remedies extracts than that of the control. Skin eleasticity (R2, R8) for those whom have applied the gel containing Chinese herbal remedies extracts increased over time during four weeks test period especial for those applying gel product containing 95% ethanol extracts showed significant better results. Skin whitening increased over time during four weeks test period but did not show a significant difference for melanin index.

碩士
嘉南藥理科技大學
化妝品科技研究所
100
Myriad of herbs have been used as traditional Chinese medicine for thousands of years. Those know ledges from Chinese ancestors have played an important role as traditional therapy in Asia. The application of herbal has been gradually emphasized in cosmetic science field, such as natural ingredients in skin care products that can be whitening, moisturizing or even exfoliate the skin. Previous research showed the bacteria in the hot springs could be used as exfoliation products and promote metabolism of skin by adding to the products. The present research will connect traditional herbs and hot spring bacteria to manufacture multi-functional skin care products. In this study，the composition of six Chinese herbal medicine in Lithosp ermumerythrorhizon, Rhinacanthus nasutus (L.) Kurz ( for Chinese ), Rhinacanthus nasutus (L.) Kurz ( for Taitung ),Toona sinensis, Taraxacum formosanum, Houttuynia cordata. selection of the best antioxidant . Re-use the Chihpen bacteria and Anoxybacillus bacteria fermentation, the products after fermentation researcher will take it to exfoliate efficacy assessment, applied in the development of exfoliating products. Take the Lithosp ermumerythrorhizon, Rhinacanthus nasutus (L.) Kurz C, Rhinacanthus nasutus (L.) Kurz T,Toona sinensis, Taraxacum formosanum Houttuynia such as six Chinese herbal medicine after extraction to assess Scavenging of Radical 1-Diphenyl-2-picrylhydrazyl assay , Scavenging of Radical Cation2，2’-azinobis-( 3-ethybenzothiazolin- 6-sulfonic acid) assay , pUC 119 DNA protection, antimicrobial capacity, total phenolic content determination and Fibroblast 3-(4,5-dimethylthiazole-2-yl) -2,5- diphenyltetrazo-liumbromide ) Experiments the cytotoxicity of the six kinds of Chinese herbs. In the product evaluation, the fermentation product by adding to spa package, shower gel and body lotion products a month human safety and efficacy of the test, and apply the products in the arm Apparatus spectrophotometric color, skin moisture analyzerdetection of the integrated skin Advisory system whitening, stretch, moisturizing and exfoliating patch. It can be seen from the experiment results similarly at antioxidant the DPPH free radicals scavenging SC50 = 335.82 μg/mL; scavenging of ABTS‧+ free radicals (SC50 = 8.23 ± 3.67 μg/mL); pUC 119 DNA protection (EC50 = 1.67 mg/mL); Antimicrobial activity, the P. acnes inhibitory (inhibition zone diameter of 12 mm); MTT assay of the Rhinacanthus nasutus (L.) Kurz C extract, more than 80% cell survival in the concentration of 0.5 mg/mL, showing that cells without apparent toxicity at this concentration. On the product evaluation, the products adding Anoxybacillus bacteria fermentation can clearly see that horny horny patch has significantly reduced. The results of this study showed that the Rhinacanthus nasutus (L.) Kurz C extract Spa fermentation products can enhance the whitening, moisturizing and exfoliating effect, so the hot springs bacteria and fermentation of Chinese herbal medicine can be developed in the application of cosmetics raw materials.