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Journal articles on the topic 'Herbal Mouth Ulcer Gel'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Shubham, Tomar* Akash Gorase Prathamesh Ware Krushna Jagzap Rushikesh Shinde. "Formulation and Evaluation of Herbal Mouth Ulcer Gel by Utilizing Psidium Guajava and Jasminum Officinale." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 351–67. https://doi.org/10.5281/zenodo.15581547.

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This study addresses the formulation and evaluation of Herbal mouth ulcer gel containing extracts of Psidium Guajava and Jasminum officinale. The herbal mouth ulcer gel is Formulation using leaves of Psidium Guajava and Jasminum officinale. The Extraction of Guava and Jasmine leaves is Prepared by Ethanolic Extraction and herbal mouth ulcer gel is Prepared by Compounding Method. The herbal mouth ulcer gel formulation was prepared by using guava leaf extract, jasmine leaf extract, Carbopol 934, methyl paraben and propyl paraben, Triethanolamine and required amount of distilled water. &nbsp

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2

Patil, Vrushali, Utkarsha Shivsharan, and Ravikant Patil. "Formulation and evaluation of guava leaf extract gel for mouth ulcer management." Indian Journal of Pharmacy and Pharmacology 9, no. 4 (2022): 247–51. http://dx.doi.org/10.18231/j.ijpp.2022.045.

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The highlight of this study was preparation of microparticles using the extract of guava leaves which led to novel drug delivery of the herbal extract. The aim of the study was to formulate a microparticles loaded gel for management of mouth ulcer. The microparticles were prepared by solvent evaporation method using the polymer, oil and liquid phase. Then the preparation of gel base was done with incorporation of microparticles. The evaluation of the microparticles and the gel was done. This study is an effort to develop a herbal gel for mouth ulcers offering better compatibility and lesser di

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3

Sachin, Bhale* Priya Jaware Prachi Murkute Ashwini Pundkar Santosh Payghan. "Formulation and Evaluation of Herbal Mouth Gel." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1522–34. https://doi.org/10.5281/zenodo.15380314.

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Ulcers are most common in the oral region, for which the patient seeks help from their Physician/dental surgeon. The presenting complaints are usually redness, burning, Sensation and/or pain. They can present in any part of the oral cavity but may be painful if it occurs in the movable area. Mouth ulcers cause pain and irritation from salty, spicy, and sour food items and may Cause discomfort while healing occurs due to the use of chemical formulations. This project Focuses on the preparation of an herbal mouth ulcer gel because it has fewer side effects. The gel was prepared by using guava le

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4

Nikita, Kor1 Pradnya Tarmale2 Vaibhavi Vishe3 Pratiksha Sonawane4. "Formulation And Evaluation of Herbal Mouth Ulcer Gel." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 846–53. https://doi.org/10.5281/zenodo.15597838.

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The current study focuses on the "Formulation and Evaluation of a Herbal Gel" that combines natural substances with therapeutic capabilities to heal mouth ulcers. Selected herbes such as Guava, Polyalthia longifolia, Curcuma longa (turmeric), Aloe vera, Capsicum were incorporated due to their anti-inflammatory, antimicrobial, and wound-healing activities. The gel was prepared using a suitable gelling agent to ensure appropriate consistency and ease of application. Physical parameters like pH, spreadability, viscosity, and stability were evaluated. The gel exhibited satisfactory physical charac

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5

Kumar, Hitesh. "Formulation & Evaluation of Aqueous Guava & Babul Leaves for the Treatment of Mouth Ulcer." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 05 (2024): 1–5. http://dx.doi.org/10.55041/ijsrem34893.

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This study delved the development and evaluation of a new herbal gel for mouth ulcers using pulverized guava leaves. The gel incorporated colorful attention of the leaves with Carbopol 934 and Propylene glycol as a base. Evaluation included assessments of the gel's physical parcels and natural exertion. Infrared spectroscopy verified no adverse commerce between the leaves and the gelatinizing agent. The performing gel was transparent, invariant, and had a neutral pH range( 7- 7.5). also, it demonstrated good rheological parcels, spreading and banishing fluently. Anti- fungal tests revealed sig

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Sambhaji Pagare, Ms Indrayani, and Mr Utkarsh Ravindra Mandage. "Formulation, Evaluation and Anti-Bacterial Activity of Herbal Gel for Mouth Ulcer by Using Jasminum Officinale." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 03 (2025): 1–9. https://doi.org/10.55041/ijsrem42498.

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Mouth ulcers are a common oral condition causing discomfort and affecting daily life. The present study focuses on the formulation, evaluation, and anti-bacterial activity of a herbal gel using Jasminum officinale (common jasmine), a plant known for its medicinal properties. The plant contains a variety of bioactive compounds, including alkaloids, flavonoids, tannins, and essential oils, which contribute to its anti-inflammatory, antioxidant, and antibacterial effects. The herbal gel was formulated by extracting active ingredients from Jasminum officinale and incorporating them into a gel base

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7

Murkute, Vishal* Dr. Datkhile S. V. "Formulation And Evaluation of Antiulcer Gel Using Extract of Spathodea Campanulata P. BEAUV." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 1077–80. https://doi.org/10.5281/zenodo.15605571.

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Spathodea Campanulata is a medicinal plant known for its potent antioxidant, anti-inflammatory, and gastroprotective properties. The present study focuses on the formulation and evaluation of an herbal antiulcer gel using extract for the treatment of oral ulcers. The bioactive compounds, including flavonoids, tannins, and alkaloids, contribute to its ulcer-healing potential by promoting tissue regeneration and reducing inflammation. The gel was formulated using a suitable polymer base, ensuring optimal viscosity, spreadability, and adherence to the oral mucosa. Various concentrations of extrac

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8

Upadhye, K., K. Charde, G. Dixit, and S. Bakhle. "Formulation and evaluation of herbal gel for management of mouth ulcers." Indian Journal of Pharmacy and Pharmacology 8, no. 3 (2021): 226–30. http://dx.doi.org/10.18231/j.ijpp.2021.039.

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: or mouth ulcers is the most common condition that we encounter. Clinically the lesions are single or multiple superficial and deep sealed and are associated with microbial invasions.: This study was conducted with the aim of evaluating the effectiveness of herbal drugs for treatment of In the research work, mouth ulcer gels were formulated incorporating the extracts of as and using 934 as the gelling agent. Seven batches were formulated by varying the concentration of the herbal ingredients (F1 to F7)The prepared formulations were evaluated for various parameters like physical appearance, pH

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9

Aarati, Shedage* Saloni Palve Santoshi Mehetre Jyoti Salgar. "Formulation And Assessment of Oral Gel for The Treatment of Mouth Ulcer Using Extract from Jamun Seed Powder." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3457–67. https://doi.org/10.5281/zenodo.15475370.

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The majority of the world's population, particularly in developing nations, still relies on herbal medicines for primary health care because they are more culturally acceptable, more compatible with the human body, and have fewer adverse effects. Herbal treatments are made from a plant or its components and are used to cure ailments, diseases, and injuries, as well as to promote health and healing. People are now more conscious of the side effects and the ingredients used in the preparation of gels and other formulations. In the Unani and Ayurvedic health systems, the native Indian Jamun (Syzy

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10

S., S. Chavan V. D. Thombare B. Shejul*. "Development And Evaluation Of Herbal Oral Gel Containing Extract Of Polyalthia Longifolia Leaves For The Treatment Of Mouth Ulcers." International Journal in Pharmaceutical Sciences 1, no. 12 (2023): 389–403. https://doi.org/10.5281/zenodo.10389752.

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The mouth ulcers are round or oval sores which give rise to redness, pain and discomfort leading to alteration of person food choice while healing process. Aphthous stomatitis and Local trauma are the most common types of oral ulcers. The aim of present study was to formulate and evaluate herbal oral gel of Polyalthia longifolia leaves extract for treatment of mouth ulcer. Polyalthia longifolia leave has been usually used to govern diseases such as treat fever, gonorrhoea, uterus ailments, mouth ulcer, heart problems and it also possesses good antimicrobial, antifungal, antibacterial activity,

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11

Ankit, P. Gondane *. Sayali V. Thote Tejaswini C. Chandel Vedika A. Kumarwar Harshita D. Bansod. "Formulation and evaluation of Herbal Mouth gel Containing Clove and Myrrh." International Journal in Pharmaceutical Sciences 3, no. 4 (2024): 694–704. https://doi.org/10.5281/zenodo.10964940.

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Clove is known as aromatic medicinal herb since ancient time. The extraction of essential oil and the chemical composition of oil from clove are describe along with antimicrobial, insecticidal, antifungal and other uses. clove oil has several benefits and is consider one of the most effective in mouth ulcer treatment.   Myrrh is used to reduce pain and kill bacteria. Myrrh preparation can be used for treatment of ulcer and inflammation in the mouth and for minor wounds.  Myrrh shows various medicinal activity such as it is used in diarrhea, parasite infection, wound healing, and

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12

Choubey, Himani. "Guava Leave Herbal Mouth Ulcer Gel Formation and Evaluation: A Review." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 2143–58. https://doi.org/10.35629/4494-100321432158.

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This article specifically addressed the management of mouth ulcers, often known as canker sores. These uncomfortable sores appear on the oral cavity's mucous membranes. The use of herbal gel to treat these ulcers is the main topic of conversation. The article explores a long number of herbs that are well-known for having a lot of flavonoids, explaining why they are so important in treating mouth ulcers. This investigation aims to clarify the effectiveness and therapeutic possibilities of flavonoid-enriched herbal treatments in reducing the discomfort brought on by this oral condition. Since an

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13

Raj, Piyush, Neha Sodiyal, and Shivanand M. Patil. "Preparation and Evaluation of Herbal Oral Gel Containing Extract of Psidium guajava Leaves for Mouth Ulcer." Journal for Research in Applied Sciences and Biotechnology 3, no. 6 (2024): 116–25. https://doi.org/10.55544/jrasb.3.6.15.

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Mouth ulcers are a common oral condition causing discomfort and pain, often interfering with daily activities like eating and speaking. Conventional treatments, such as synthetic gels and medications, can sometimes result in side effects or high costs, which has led to growing interest in natural and herbal alternatives. Herbal formulations are known for their safety, affordability, and effectiveness. Psidium guajava (guava) leaves have been widely recognized in traditional medicine for their antimicrobial, anti-inflammatory, and wound-healing properties. Rich in bioactive compounds such as fl

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14

Gaware, Miss Gayatri B. "Formulation and Evaluation Herbal Gel from Psidium Guajava and Jasminium Officinali for Mouth Ulcer Treatment." International Journal for Research in Applied Science and Engineering Technology 12, no. 6 (2024): 2449–54. http://dx.doi.org/10.22214/ijraset.2024.63500.

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Abstract: India has long employed traditional or herbal medicine to diagnose, treat, and prevent illness. The study's objective was to create and assess a herbal gel that contained extract from jasmine officinale and Psidium guajava for the treatment of mouth ulcers. Herbal gel made using powdered extracts of Psidium guajava and Jasminum officinale at varying concentrations. Psidium guajava has high antifungal and antibacterial action and is used to treat a number of illnesses, including diabetes mellitus, diarrhea, rheumatism, wounds in the throat, and coughs. Tannins, flavonoids, triterpene,

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15

Sandra, P.* Safa P. K. Femina Arippayil Arun Prakash K. V. Hiba Musthafa K. P. Nandana P. "Anticancer Activity of Coleus Amboinicus." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 251–62. https://doi.org/10.5281/zenodo.15332193.

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Ulcers are most common in the oral region, for which the patient seeks help from their Physician/dental surgeon. The presenting complaints are usually redness, burning, Sensation and/or pain. They can present in any part of the oral cavity but may be painful if it occurs in the movable area. Mouth ulcers cause pain and irritation from salty, spicy, and sour food items and may Cause discomfort while healing occurs due to the use of chemical formulations. This project Focuses on the preparation of an herbal mouth ulcer gel because it has fewer side effects. The gel was prepared by using guava le

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16

K. Mishra, Nikunja, Uma Mudi, Jyotirmayee Behera, and Amiyakanta Mishra. "INVESTIGATING THE EFFECTS OF POLYHERBAL GEL ON PHENOL-INDUCED ORAL APHTHOUS ULCERS IN RATS." INDIAN DRUGS 62, no. 02 (2025): 78–85. https://doi.org/10.53879/id.62.02.15037.

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Aphthous ulcers, commonly known as canker sores, are among the most widespread oral diseases globally. They typically occur on the non-keratinized mucosal surfaces inside the mouth, including the inner lips, floor of the mouth, and the underside of the tongue. Herbal therapy plays an important role in the healing process of diseases without causing any significant side effects. This study investigates the effects of polyherbal gel (PHG) on phenol-induced oral aphthous ulcers in rats. The rats were randomly assigned to five experimental groups; PHG 5%, 10% and 20% w/V were administered topicall

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Somesh, O. Kale1* Ashvini B. Deshmukh2. "Polyherbal Gel For Management Of Mouth Ulcer: A Review." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 247–53. https://doi.org/10.5281/zenodo.11127319.

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The main purpose of this gel formulation of Guava leaves, Neem leaves, Mango leaves, Jasmine leaves, Jamun leaves was to relieve pain and discomfort due to oral ulcers. As we know there are different types of sores in the mouth that cause inflammation and pain. The most common oral ulcers are Local trauma & Aphthous Stomatitis. Now many over-the-counter medications are essential to staying in primary health care because of the positive response and the most effective treatment with the least amount of side effects. Herbal medicines are still the backbone of almost 75-80% of the world's pop

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18

Anggraeni, Dian, Kamaluddin Kamaluddin, and Theodorus Theodorus. "Effectiveness of Garlic Water Extract Gel (Allium sativum. L) Against Necrotic Factor Alfa Tumors and Mouth Ulcer Diameter in Wistar White Male Rats." Biomedical Journal of Indonesia 6, no. 1 (2020): 27–34. http://dx.doi.org/10.32539/bji.v6i1.7970.

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Oral ulcers are pathological conditions that are characterized by loss of epithelial tissue, causing inflammation. During inflammation, the inflammatory mediator is TNF will increase. Therefore, drugs are needed to suppress TNF-levels to suppress inflammation. One of the herbal ingredients that can suppress inflammation is garlic. In vivo laboratory experimental research with pre-post systems. The samples used were 36 male Wistar white rats divided into 6 groups (6 individuals / groups), namely the group without drug treatment (as pre-treatment data), negative control group namely HPMC gel bas

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Aakif, Hashmi Dr. Shivappa N. Nagoba* Atiya Shaikh Akhilesh Limaye Shripal Kolsure Harshada Ghuge. "Review On: Anti-inflammatory Polyherbal Gel for Bacterial Skin Infections." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4696–704. https://doi.org/10.5281/zenodo.15543055.

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Medicinal plant is used ancient India. The study of medicinal plants used in wound healing and skin repairing and properties. The present study was prepared wound healing activity a poly herbal gel formulation. The study also aimed to evaluate the impact of polyherbalism on antimicrobial, antioxidant and anti-inflammatory effect there after ratio of ayurvedic drug was optimize according to treat the wound. Polyherbal gel are tested on organism on suitable complete agar medium in petri dishes, cup. where they are used in plant leaves, bark and route, stem etc. they are used in therapeutic purpo

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Deepika, K., A. Sairoja, and P. Sri Jyothi. "Creation and Assessment of Herbal Gel with Guava Leaf Extract." E3S Web of Conferences 564 (2024): 07003. http://dx.doi.org/10.1051/e3sconf/202456407003.

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Mouth ulcers, a common oral mucosal disorder, can cause discomfort and interfere with daily activities. Natural remedies like guava leaves extract have shown promising potential in managing such conditions due to their anti-inflammatory and antimicrobial properties. This study aimed to formulate and evaluate an aqueous gel of guava leaves extract for the treatment of mouth ulcers. The guava leaves extract was prepared using a maceration method and incorporated into a gelbase consisting of Carbopol 934P. Various formulations were prepared with different concentrations of guava leaves extract to

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Vishnu, Rajbhar. "FORMULATION AND DEVELOPMENT OF AYURVEDIC LOZENGES FOR MOUTH ULCER AND HEALTHIER DIGESTION." International Journal of Scientific Development and Research 8, no. 6 (2023): 1702–5. https://doi.org/10.5281/zenodo.8396596.

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Mouth ulcers, also known as canker sores, are small, painful lesions present in the buccal cavity with a reddish border that appears to be white or yellow in the middle. The area across the ulcer gets enlarged. It can be caused by various factors such as stress, hormonal changes, consuming highly acidic foods, and some dental procedures such as dental fillings. In this article, the major aim is to formulate oral ayurvedic lozenges that are beneficial for local delivery of drugs in the oral cavity. The rate of dissolution and disintegration time of lozenges are high, which leads to rapid on-set

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Aditi, Rajendra Late* Kadam Vaibhav N. Dr. Rahane Rahulkumar D. "Synthesis and in vitro Evaluation of Novel Thiophene Derivatives." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3541–46. https://doi.org/10.5281/zenodo.15478486.

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sulfur-containing heterocycles used to create a wide variety of sophisticated compounds with a wide range of biological functions, they are valuable analogs for medicinal chemists. Synthesis novel thiophene derivative by Schiff base were validated by FTIR, MS and 1H-NMR. The produced compounds were additionally assessed for their in vitro biological potentials, specifically antimicrobial activity against chosen microbial species utilizing tube dilution method. Antimicrobial screening outcomes revealed that compound S1 emerged as the most effective antibacterial agent against Staphylococcus aur

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Madanahalli Ramesh, Manoj, and Annegowda Hardur Venkatappa. "Unlocking traditional remedy: Gulkand-enhanced mucoadhesive gel for canker sore relief." International Journal of Secondary Metabolite 11, no. 4 (2024): 658–74. http://dx.doi.org/10.21448/ijsm.1417041.

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This study focuses on the development and evaluation of mucoadhesive gel formulations containing different Gulkand and its extract with a specific emphasis on their potential for managing oral health conditions, including the discomforting issue of mouth ulcers. The formulations underwent a thorough analysis, encompassing the assessment of phenolic compounds responsible for antioxidant activity, in addition to comprehensive physical, chemical, and pharmacological evaluations to determine their suitability for commercial utilization. Mouth ulcers are a prevalent oral health concern that can cau

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Rutuja, Jaiswal* Tejaswini Dhawale Dr. Gajanan Sanap. "Herbs Therapies for Mouth Ulcer." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 2493–501. https://doi.org/10.5281/zenodo.14524961.

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Ulcer is a common disorder which is seen among many people. In most cases, it is an inflammatory skin rupture. There are many types of ulcers such as mouth ulcer, peptic ulcer, oesophagus ulcer, gastric ulcer. Among these mouth ulcers is common type of ulcer. Throughout the ages, treat a variety of illnesses and diseases. Mouth ulcers or aphthous ulcers are common oral lesions characterized by painful, shallow sores on the mucous membranes. This abstract explores the causes, symptoms, and potential treatments for mouth ulcers, emphasizing their impact on oral health and quality of life. Nowada

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Gondkar, Sanika Sanjay. "Therapeutic Potential of Jasmine Herbal Lozenges in the Treatment of Recurrent Aphthous Stomatitis." International Journal for Research in Applied Science and Engineering Technology 13, no. 5 (2025): 5170–79. https://doi.org/10.22214/ijraset.2025.71397.

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Mouth ulcers, also known as aphthous ulcers, are common inflammatory lesions that affect the mucous membranes of the oral cavity. They can cause significant discomfort, pain, and difficulty in eating, drinking, and speaking. Conventional treatments, such as topical corticosteroids and antiseptic gels, often provide temporary relief and may have undesirable side effects. In response to the growing demand for safe and effective natural remedies, this study focuses on the formulation and evaluation of herbal lozenges containing Jasminum sambac (jasmine) extract for the treatment of mouth ulcers.

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Mihir Makwana, Mihir Makwana, Prof Hiral S. Popaniya Prof. Hiral S. Popaniya, Dr Payal Vaja Dr. Payal Vaja, Smruti Sankhat Smruti Sankhat, and Vadariya Priya Vadariya Priya. "A Systematic Review of Herbal Approaches for Mouth Ulcer Management." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 1759–68. https://doi.org/10.35629/4494-100217591768.

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The mouth ulcer is common disorder caused by various etiological factor. These oral ulcers, often referred to as tiny sores, are painful lesions that typically appear along the gum line inside the mouth. They frequently cause discomfort and pain. Which can influence a person’s food choices during the healing process. The aim of this work is to evaluate the effectiveness and safety of different herbal remedies for treating and managing mouth ulcer. Numerous formulations, both synthetic and natural, are available on the market. Herbal remedies play a crucial role in primary healthcare due to its

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Babu, K. Anand, and R. Ram Narayanan. "A Review on unexplored Plants for Recurrent Aphthous Stomatitis." International Journal of PharmTech Research 13, no. 3 (2020): 253–60. http://dx.doi.org/10.20902/ijptr.2019.130316.

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Recurrent Aphthous Stomatitis (RAS) is one of the most common pathological conditions with ulcers in the oral mucosa. Various conventional medicines are available in the market for RAS but due to a range of factors people are getting affected by RAS gradually. More over conventional medicines are all having the side effects so the alternative system for the treatment of RAS came in to the market. Although herbal medicines are widely used in India and other countries and multiple studies are conducted in this regard, but still many of the herbal plants are not utilized though they are having tr

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Pathan, Irfan Mustafa, Vishal S. Madankar, and Anil B. Panchal. "Formulation and Evaluation of Guava Leaf-Based Nanogel for Mouth Ulcer Treatment." Journal of Drug Delivery and Therapeutics 15, no. 4 (2025): 13–19. https://doi.org/10.22270/jddt.v15i4.7069.

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Mouth ulcers, also known as aphthous ulcers, are painful lesions affecting the oral mucosa, causing discomfort and irritation. Conventional treatments, such as antiseptic gels and corticosteroids, provide temporary relief but may have side effects with prolonged use. Guava leaves (Psidium guajava) contain bioactive compounds such as flavonoids, tannins, and polyphenols, which exhibit antimicrobial, anti-inflammatory, and wound-healing properties. This study focuses on the formulation of a simple, Nanogel using Carbopol 934 as a base for the treatment of mouth ulcers. The gel was prepared by in

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Septiyan, Taufik, Gofarana Wilar, and Nasrul Wathoni. "Herbal Medication of Recurrent Aphthous Stomatitis: A Narrative Review." Bioscientia Medicina : Journal of Biomedicine and Translational Research 6, no. 1 (2021): 1318–23. http://dx.doi.org/10.37275/bsm.v6i1.438.

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A mouth ulcer or recurrent aphthous stomatitis (RAS) is a mouth mucous tissue inflammation. This disease mainly occurs in patients 10-40 years of age, preferably in women and high socioeconomic backgrounds. The cause of mouth ulcers or RAS could be trauma, infection, digestive problems, or blood disorders. Herbal practitioners widely use herbs, folks, and society to treat various diseases. This research aimed to describe the herbal treatment for RAS. The review results show there are nine plants with the ability to cure RAS, they are Persea americana Mill., Averrhoa bilimbi L., Abrus precatori

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Sahu, Bhuneshwari, Payal Sahu, Shikha Sahu, et al. "A Review On: Formulation and Evaluation Herbal Lozenges for Mouth Ulcer." International Journal of Advanced Multidisciplinary Research and Studies 5, no. 1 (2025): 1280–83. https://doi.org/10.62225/2583049x.2025.5.1.3794.

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Cancer wounds, additional designation aimed a ten trance boils, remain minute, sore cuts that look white before yellow in the center and have a reddish border. It enlarges the region across the ulcer. Numerous things, including stress, hormone fluctuations, eating meals high in acid, and some dental treatments like dental fillings, might contribute to it. Creating oral herbal lozenges that are advantageous for local medicine administration in the mouth cavity is the main goal of this study. Lozenges have a quick onset of action due to their high rate of dissolution and disintegration time. Gua

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Astanti, Mahardiani Dwi, Pujiana Endah Lestari, and Iin Eliana Triwahyuni. "Efektivitas Gel Esktrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) terhadap Penyembuhan Ulser Pada Tikus Wistar." STOMATOGNATIC - Jurnal Kedokteran Gigi 19, no. 1 (2022): 7. http://dx.doi.org/10.19184/stoma.v19i1.30693.

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Ulcer is a lesion that is often found in the oral cavity that causes discomfort, pain, difficulty speaking and difficulty eating. Nowdays, herbal ingredients are widely used as alternative medicine choice besides drugs on the market. Pandan leaf contains flavonoids, alkaloids, saponins, and polyphenols which have antiinflammatory, antibacterial, and antioxidant abilities, allowing faster healing of ulcers. Purpose of this study was to determine the effect of pandanus leaf extract gel on healing ulcers and determine the most effective concentration in healing ulcers. This study used 25 Wistar r

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Janićijević-Hudomal, S., D. Dekanski, and J. Rašić. "EFFICACY OF PLANT KINGDOM ON STRESS - ULCER DEVELOPING." Praxis medica 35, no. 2 (2007): 85–88. http://dx.doi.org/10.70949/pramed200702207j.

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&lt;p&gt;Despite progress in conventional pharmacology in producing effective drugs, the plant kingdom might provide a useful source of new anti-ulcer compounds for development pharmaceutical entities or, alternatively, as simple dietary adjuncts to existing therapies. Botanical compounds with anti-ulcer activity include flavonoids(i.e.quercetin, naringin, silymarin, anthocyanosides, sophoradin derivatives) saponins (i.e. from Panax japonicus and Kochia scoparia), tannins (i.e. from Linderae umbellatae), gums and mucilages (i.e. gum guar and myrrh). This article reviews the gastro-prot

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Saraladevi V, Ravichandran S, Bhavani J, Satheesh Kumar D, Chandrasekaran A R, and Irfana Asma S. "Antibacterial Activity of the Herbal Gargles." International Journal of Pharmacometrics and Integrated Biosciences 4, no. 2 (2019): 14–17. http://dx.doi.org/10.26452/ijpib.v4i2.1255.

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Teeth and mouth are the supportive organs to enable us in doing all the functions of the body by consuming. So, cleanliness of the oral areas is important for the healthy and nourished body which is devoid of microorganisms. Herbs have been in the investigations for the antibacterial and antiviral properties along with the history of the medical systems. They were effective and safer relative to the available synthetic drugs. Three formulations of gargle were prepared using Extract of Neem, Aloe Gel and clove oil which were named as GNF, GAF and GCF. The physical parameters were estimated, suc

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Sahu, Rimjhim, Deepika Jain, Rekha Mehani, Hemani ., Lal Hingorani, and Vijay Thawani. "Novel poly herbal muco-adhesive formulation for treatment of oral aphthous ulcer." International Journal of Basic & Clinical Pharmacology 10, no. 8 (2021): 906. http://dx.doi.org/10.18203/2319-2003.ijbcp20212811.

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Background: Oral ulcers are the most frequent lesions that cause discomfort for which the patients seek treatment for alleviating pain and facilitate early healing. Various treatment modalities from modern medicine and Ayurveda are used in the form of ointments and mouthwashes with varying efficacy. Anti-inflammatory medicines, enzymatic preparations, gamma globulins and immune suppressants have been used.Methods: Extracts of five chosen herbs, Glycyrrhiza glabra, Acacia catechu, Punica Granatum, Curcuma longa and Mentha piperita were used for preparing mucoadhesive gel for the treatment of or

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Iswariya, Vangala Tulasi, Anees Mohammad, Kota Sanihitha, Neerudi Sai kiran, and Tadikonda Rama Rao. "Multipurpose Topical Herbal Gel – A Review Article." Biosciences Biotechnology Research Asia 22, no. 2 (2025): 425–34. https://doi.org/10.13005/bbra/3373.

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ABSTRACT: The current study attempts to create and assess an herbal gel with natural elements that has a therapeutic impact without causing any adverse effects. Protectants, antiseptics, and antimicrobials are just a few of the uses for it topically. The term "herbal formulations" refers to a dosage form that contains one or more herbs or processed herbs in precise amounts to offer particular nutritional and cosmetic benefits intended for use in the diagnosis, treatment, and mitigation of human or animal diseases as well as in modifying the physiology or structure of subjects. Carbapol was use

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Sanchit S. Gaikwad, Manoj P. Jaybhaye, Dipali R. Khandagale, and Prajakta S. Randive. "Medicated herbal chewing Gum to treat ulcers in mouth using Licorice and Capsicum annuum." World Journal of Biology Pharmacy and Health Sciences 20, no. 2 (2024): 270–77. http://dx.doi.org/10.30574/wjbphs.2024.20.2.0868.

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This study explores the formulation and evaluation of herbal chewing gum containing extracts from Licorice (Glycyrrhiza glabra) and Capsicum Annuum, aimed at treating mouth ulcers. Licorice derived from roots. are known for their medicinal properties, it contains glycyrrhizin which is responsible for its sweet taste, including effects on sore throats, reduce inflammation and aid digestion. They contain various chemical compounds flavonoids such as such as liquirtin, rhamnoliquirilin, liquiritigenin, prenyllicoflavone A, glucoliquiritin apioside, metho-xyphaseolin, shinpterocarpin, shinflavanon

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Ani Megawati and Riani Setiadhi. "Herbal Medicines as Adjunctive Therapy for Oral Squamous Cell Carcinoma Management: a Case Report." Dentika: Dental Journal 25, no. 2 (2022): 85–90. http://dx.doi.org/10.32734/dentika.v25i2.9410.

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Oral Squamous Cell Carcinoma (OSCC) is the most frequent oral cancer. The management for OSCC are surgery, chemotherapy, and radiotherapy. Chemotherapy and radiotherapy have high toxicity and side effects, therefore effort are needed to reduce them. Several studies show that herbal medicines have anticancer effects with lower toxicity and side effects. The objective is to discuss about management of OSCC using chemotherapy and anticancer herbal medicines as adjunctive therapy. A 59-year-old man came to the oral medicine clinic complaining a painful ulcer on the right tongue since 8 months ago.

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Shams, Salman, Uzma Tariq, Saba Parveen ,. Soomro, et al. "Assessment between Aloe Vera Gel and Intralesional Hydrocortisone in the Management of Stage II Oral Submucous Fibrosis." Pakistan Journal of Medical and Health Sciences 16, no. 4 (2022): 637–39. http://dx.doi.org/10.53350/pjmhs22164637.

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Objective: To assess the effect of aloe vera gel and intralesional hydrocortisone in the management of stage II oral submucous fibrosis patients in terms of mouth opening and burning sensation. Subject and Methods: A total of 38 patients were equally divided into two groups; i.e Group A was treated with herbal antioxidant aloe vera gel, while Group B was treated with traditional intralesional hydrocortisone. Patients of stage II OSMF were diagnosed clinically on the basis of presenting symptoms. Mouth opening and burning sensations were recorded at start of treatment and postoperatively for 3

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Pranali, R. Gajbhiye* Jagdish V. Manwar Abhijit R. Raut. "Formulation And Optimization Of Polyherbal Gel For Management Of Aphthous Stomatitis." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 1202–7. https://doi.org/10.5281/zenodo.10894485.

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Aphthous stomatitis is the most common condition we encounter. Clinically, the lesions are simple or multiple superficial and deeply sealed and are associated with microbial invasions. This study was conducted to evaluate the efficacy of herbal medicines in the treatment of Aphthous stomatitis. In research work, oral ulcer gels containing extracts of Psidium guajava, Ocimum tenuiflorum, and Azadirachta indica were formulated using Carbopol 934 as a gelling agent. Seven batches were formulated by varying the concentration of herbal ingredients (F1 to F7). The prepared preparations were evaluate

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Pranav Ramchandra Deshmane, Siddhart Bhaskar Jadhav, Sachin V. Datkhile, and Rahul P. Lokhande. "Formulation and evaluation of a mouth ulcer gel using Clitoria ternatea flower extract." World Journal of Biology Pharmacy and Health Sciences 22, no. 3 (2025): 064–71. https://doi.org/10.30574/wjbphs.2025.22.3.0547.

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Mouth ulcers, also known as aphthous stomatitis, are common, painful lesions that affect the mucosal surfaces of the oral cavity. Their pathophysiology is complex, involving genetic, immunological, and environmental factors. Although the exact cause remains unclear, dysregulation of the immune system plays a central role. Inflammatory responses are triggered by the activation of T lymphocytes, which lead to the release of cytokines, resulting in epithelial cell damage and ulcer formation. Genetic predisposition, stress, trauma, nutritional deficiencies (especially of B vitamins, folic acid, an

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Dipak, R. Kale1* Ram B. Ingle2 Priyanka A. Narode3 Paavanraj B. Lodwal4 Vaishnavi N. Borhade5. "Research On Preparation, Evaluation And Comparison Of Herbal Toothpaste With Marketed Herbal Toothpaste." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 337–45. https://doi.org/10.5281/zenodo.12662136.

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In current scenario in oral dental care with use of herbal toothpaste containing natural ingredients are moreacceptable in public belief than chemical based synthetic formulations due to their safety and efficacy inreducing dental caries, and preventing other dental issues to which this generation is prone to. In this formulationwe utilizes aloe vera gel, clove oil, neem powder, pomegranate peel powder and trikatu which are not yet usedby any other research work. These extracts possess many activities like anti-ulcer, anti-caries, anti- bacterial,wound healing along with which it imbibes certa

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Daphne, Sherine S.*1 Ravichandran S.2 Abjel A.3 Gopi S.4 Sukesh Kumar B.5. "Formulation And Evaluation Study Of Herbal Buccal Patch For Mouth Ulcer With Curcumalonga & Glycyrrhiza Glabra." International Journal in Pharmaceutical Sciences 2, no. 4 (2024): 252–76. https://doi.org/10.5281/zenodo.10927714.

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Mucoadhesion has been a major emphasis in pharmaceutical technology since the 1980s, resulting in the creation of drug delivery systems for the oral, buccal, nasal, rectal, and vaginal routes. Mucoadhesive dosage formulations are ideal for oral delivery because of their smooth surfaces, controlled release, and high drug loading capacity. There are two types of buccal patches: matrix and reservoir, the latter of which has a cavity separate from the adhesive. Bioadhesive oral medicine can be delivered in the form of pills, patches, films, semisolids, and powders. Buccal patches provide various b

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Senthilkumar, K. L., S. Venkateswaran., A. Vasanthan, et al. "Formulation development and evaluation of novel herbal toothpaste from natural source." International Journal of Pharmaceutical Chemistry and Analysis 9, no. 1 (2022): 17–21. http://dx.doi.org/10.18231/j.ijpca.2022.003.

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Herbal toothpaste with natural ingredients is more acceptable in public opinion than chemical-based synthetic formulations in the current oral dental care scenario due to their safety and efficacy in reducing dental caries and preventing other dental disorders to which this generation is prone. In this composition, we use aloe Vera gel, clove oil, Neem powder, pomegranate peel powder, all of which have never been used before in any research. These extracts have anti-ulcer, anti-caries, anti-bacterial, and wound-healing properties, as well as certain unique properties including anti-cancer and

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Shaikh, S., A. Shete, and R. Doijad. "Formulation and Evaluation Pharmaceutical Aqueous Gel of Powdered Guava Leaves for Mouth Ulcer Treatment." Pharmatutor 6, no. 4 (2018): 32. http://dx.doi.org/10.29161/pt.v6.i4.2018.32.

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Rao, Deepika Pawar Chandrashekara, Nagarjuna Reddy YV, Swet Nisha, Samyuktha Balaji, MP Venkatesh, and KG Rajeshwari. "Comparison of efficacies of azithromycin & doxycycline as local drug delivery agents in treatment of chronic periodontitis − A clinical and microbiological study." International Journal of Nutrition, Pharmacology, Neurological Diseases 13, no. 4 (2023): 243–49. http://dx.doi.org/10.4103/ijnpnd.ijnpnd_42_23.

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Introduction: Periodontitis causes tissue destruction and host-microbial interactions can lead to dysbiosis. Nonsurgical periodontal therapy helps in eliminating microbial insult and adjunctive therapies like local drug administration comprising of antibiotics, pre- and probiotics and herbal therapy helps in better periodontal tissue healing.The present study aims at evaluation of efficacy of 0.5% azithromycin (AZM) and 5% doxycycline (DOX) as local drug delivery agents in the treatment of chronic periodontitis. Materials and methods: A total of 66 subjects diagnosed with chronic periodontitis

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Prasetyaningrum, Nenny, and Sofi Isna Marwati. "BLOOD VESSELS EVALUATION IN WISTAR RATS LABIAL ULCER AFTER GIVING NANOTRANSFERSOME GEL OF LIME PEEL (CITRUS AURANTIFOLIA SWINGLE) EXTRACT." E-Prodenta Journal of Dentistry 7, no. 1 (2023): 764–76. https://doi.org/10.21776/ub.eprodenta.2023.007.01.5.

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Background: Wound healing process has some characteristics, one of them is angiogenesis. Lime peel extract (Citrus aurantifolia Swingle) contains substances that play role in wound healing process. Objectives: This research aims to evaluate the blood vessels in labial ulcer after giving nanotransfersome gel of lime peel (Citrus aurantifolia Swingle) extract. Methods: This research used 32 wistar rats that divided into 8 groups, there are groups that untreated, groups that treated with lime peel gel extract, lime peel nanotransfersome gel extract, and Aloe vera-based herbal medicine respectivel

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Pandya, Maitreyi, Anupama N. Kalappanavar, Rajeshwari G. Annigeri, and Dhanya S. Rao. "Relative Efficacy of Quercetin Compared with Benzydamine Hydrochloride in Minor Aphthae: A Prospective, Parallel, Double Blind, Active Control, Preliminary Study." International Journal of Dentistry 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/7034390.

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Background and Objectives. Recurrent aphthous stomatitis is an inflammatory condition present since ancient era wherein numerous treatment modalities have been tried. But complete eradication of the disease has not been possible and hence newer agents are being introduced. One such agent is a flavonoid named quercetin with proven antioxidant, anti-inflammatory, and ulcer healing properties. Methods. 40 patients with minor aphthous ulcers were divided equally into two groups: A and B. Group A patients were advised to apply quercetin gel and Group B patients were advised to take benzydamine hydr

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Ahmadian, Roohollah, Roodabeh Bahramsoltani, André Marques, Roja Rahimi, and Mohammad Farzaei. "Medicinal Plants as Efficacious Agents for Diabetic Foot Ulcers: A Systematic Review of Clinical Studies." Wounds : a compendium of clinical research and practice 33, no. 6 (2021): 207–18. http://dx.doi.org/10.25270/wnds/2021.207218.

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A diabetic foot ulcer (DFU) is a chronic, nonhealing wound that occurs in approximately 15% to 25% of patients with diabetes, and amputation is necessary in approximately 5% to 24% of these patients. Medicinal plants have demonstrated promising wound healing activities in animal models of DFUs as well as in clinical studies. These plants, which are described as medicinal in different regions of the world, are not considered to be standard medicinal treatments in Western medicine at this time. Some medicinal products, such as bromelain—an herbal protease currently used for enzymatic debridement

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Abd Alrazaq Hassan, Manar. "Histological Determination of Cinnamon and Olive Oil Extract on Traumatic Oral Ulcer in Laboratory Rabbit." Diyala Journal of Medicine 27, no. 1 (2024): 111–22. http://dx.doi.org/10.26505/djm.v27i1.1146.

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Background: The mucosa of oral cavity is the mucous membrane which covers the tissues of the mouth cavity. In order to repair damage from a local aggressor, many cell strains and their byproducts work together throughout the vital physiological process of wound healing. This process culminates in tissue repair and starts relatively early in the inflammatory phase. . The supplements of cinnamon and olive oil can dramatically raise blood levels of antioxidants while lowering those of inflammatory indicators like C-reactive protein. Objective: The aim of the study was to determine the local histo

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Humam M. Al-Somaiday, Manar E. Al-Samaray, and Ali Al-Samydai. "Role of Herbal Medicine in Oral and Dental Health; Ethnopharmacological Study of Medicinal Plants in Iraq/Baghdad." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 553–60. http://dx.doi.org/10.26452/ijrps.v11i1.1857.

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Dental/Oral diseases are one of the major public health problems globally. The application of Herbal medicines for the manager of oral diseases are considered as an effective alternative to synthetic compound due to their lower side effect. The object of This study is a study of the traditional medicine role in dental health, based on active constituents in herbal medicines, which have been practiced by people. in this study, we sought to gather information from Bedouins in Baghdad region of Iraq about used herbs medicine in dental health. depth interviews (unstructured interviews) are used to

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