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1

Cohen, Susan M., Mary Ellen Rousseau, and Elizabeth H. Robinson. "Therapeutic Use of Selected Herbs." Holistic Nursing Practice 14, no. 3 (April 2000): 59–68. http://dx.doi.org/10.1097/00004650-200004000-00010.

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2

Walker, Ann F. "Herbs of choice: The therapeutic use of phytomedicinals." Trends in Pharmacological Sciences 16, no. 2 (February 1995): 76–77. http://dx.doi.org/10.1016/s0165-6147(00)88982-8.

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3

Szapary, Philippe O. "Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals." Annals of Internal Medicine 132, no. 12 (June 20, 2000): 1012. http://dx.doi.org/10.7326/0003-4819-132-12-200006200-00040.

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4

Bidlack, Wayne R. "Tyler’s Herbs of Choice: The Therapeutic Use of Phytochemicals." Journal of the American College of Nutrition 20, no. 3 (June 2001): 265–66. http://dx.doi.org/10.1080/07315724.2001.10719043.

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5

Korabelnikova, E. A., and Al B. Danilov. "Use of drugs of medicinal herbs for insomnia treatment." Medical alphabet 2, no. 19 (November 26, 2019): 11–18. http://dx.doi.org/10.33667/2078-5631-2019-2-19(394)-11-18.

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Therapy with medicinal herbs in the complex of therapeutic actions for insomnia occupies a special place. The main advantage of phytotherapy of sleep disorders is their high therapeutic efficacy in the absence of side effects, except in cases of individual sensitivity to individual components of the drug. Unlike synthetic drugs, drugs, which are based on vegetable raw materials, have a rapid effect on the extracellular and intracellular metabolic processes. Therefore, the therapeutic effect of medicinal plants is persistent and prolonged. The method of phytotherapy is an alternative and highly effective method of treatment of insomnia, and it should not reject, but significantly complement other methods of modern medicine.
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6

Ogzewalla, C. Dwayne. "New Publication: Herbs of Choice: The Therapeutic Use of Phytomedicinals." Journal of Pharmacy Technology 11, no. 5 (September 1995): 197–98. http://dx.doi.org/10.1177/875512259501100504.

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7

Santos-Neto, Leopoldo Luiz dos, Maria Alice de Vilhena Toledo, Patrícia Medeiros-Souza, and Gustavo Almeida de Souza. "The Use of Herbal Medicine in Alzheimer's Disease—A Systematic Review." Evidence-Based Complementary and Alternative Medicine 3, no. 4 (2006): 441–45. http://dx.doi.org/10.1093/ecam/nel071.

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The treatments of choice in Alzheimer's disease (AD) are cholinesterase inhibitors and NMDA-receptor antagonists, although doubts remain about the therapeutic effectiveness of these drugs. Herbal medicine products have been used in the treatment of Behavioral and Psychological Symptoms of Dementia (BPSD) but with various responses. The objective of this article was to review evidences from controlled studies in order to determine whether herbs can be useful in the treatment of cognitive disorders in the elderly. Randomized controlled studies assessing AD in individuals older than 65 years were identified through searches of MEDLINE, LILACS, Cochrane Library, dissertation Abstract (USA), ADEAR (Alzheimer's Disease Clinical Trials Database), National Research Register, Current Controlled trials, Centerwatch Trials Database and PsychINFO Journal Articles. The search combined the terms Alzheimer disease, dementia, cognition disorders, Herbal, Phytotherapy. The crossover results were evaluated by the Jadad's measurement scale. The systematic review identified two herbs and herbal formulations with therapeutic effects for the treatment of AD:Melissa officinalis,Salvia officinalisand Yi-Gan San and BDW (Ba Wei Di Huang Wan).Ginkgo bilobawas identified in a meta-analysis study. All five herbs are useful for cognitive impairment of AD.M. officinalisand Yi-Gan San are also useful in agitation, for they have sedative effects. These herbs and formulations have demonstrated good therapeutic effectiveness but these results need to be compared with those of traditional drugs. Further large multicenter studies should be conducted in order to test the cost-effectiveness of these herbs for AD and the impact in the control of cognitive deterioration.
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8

Lee, Gihyun, and Hyunsu Bae. "Therapeutic Effects of Phytochemicals and Medicinal Herbs on Depression." BioMed Research International 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/6596241.

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Background. Depression is a recurrent, common, and potentially life-threatening psychiatric disease related to multiple assignable causes. Although conventional antidepressant therapy can help relieve symptoms of depression and prevent relapse of the illness, complementary therapies are required due to disadvantage of the current therapy such as adverse effects. Moreover, a number of studies have researched adjunctive therapeutic approaches to improve outcomes for depression patients. Purpose. One potential complementary method with conventional antidepressants involves the use of medicinal herbs and phytochemicals that provide therapeutic benefits. Studies have revealed beneficial effects of medical herbs and phytochemicals on depression and their central nervous system mechanism. Here, we summarize the current knowledge of the therapeutic benefits of phytochemicals and medicinal herbs against depression and describe their detailed mechanisms. Sections. There are two sections, phytochemicals against depression and medical herbs against depression, in this review. Conclusion. Use of phytomedicine may be an alternative option for the treatment of depression in case conventional drugs are not applicable due to their side effects, low effectiveness, or inaccessibility. However, the efficacy and safety of these phytomedicine treatments for depression have to be supported by clinical studies.
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9

Alanazi, Hamad H., Abdelbaset Mohamed Elasbali, Maged K. Alanazi, and Eman Fawzy El Azab. "Medicinal Herbs: Promising Immunomodulators for the Treatment of Infectious Diseases." Molecules 28, no. 24 (December 12, 2023): 8045. http://dx.doi.org/10.3390/molecules28248045.

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Humans are constantly at high risk of emerging pandemics caused by viral and bacterial infections. The emergence of new pandemics is mainly caused by evolved viruses and bacteria that are highly resistant to existing medications. The rapid evolution of infectious agents demands the urgent investigation of new therapeutic strategies to prevent and treat these infections at an early stage. One of these therapeutic strategies includes the use of medicinal herbs for their antibacterial and antiviral properties. The use of herbal medicines as remedies is very ancient and has been employed for centuries. Many studies have confirmed the antimicrobial activities of herbs against various pathogens in vitro and in vivo. The therapeutic effect of medicinal herbs is mainly attributed to the natural bioactive molecules present in these plants such as alkaloids, flavonoids, and terpenoids. Different mechanisms have been proposed for how medicinal herbs enhance the immune system and combat pathogens. Such mechanisms include the disruption of bacterial cell membranes, suppression of protein synthesis, and limitation of pathogen replication through the inhibition of nucleic acid synthesis. Medicinal herbs have been shown to treat a number of infectious diseases by modulating the immune system’s components. For instance, many medicinal herbs alleviate inflammation by reducing pro-inflammatory cytokines (e.g., tumor necrosis factor-alpha (TNF-α), interleukin-1, IL-6) while promoting the production of anti-inflammatory cytokines (e.g., IL-10). Medicinal herbs also play a role in defense against viral and intracellular infections by enhancing the proliferation and functions of natural killer cells, T-helper-1 cells, and macrophages. In this review, we will explore the use of the most common herbs in preventing and treating infectious and non-infectious diseases. Using current and recently published studies, we focus on the immunomodulatory and therapeutic effects induced by medicinal herbs to enhance immune responses during diseases.
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10

Parihar, Shweta, Chattarpal C, and Devender Sharma. "To Review on Aromatherapy and Herbs List Use in Aromatherapy." Asian Journal of Pharmaceutical Research and Development 10, no. 1 (February 15, 2022): 29–31. http://dx.doi.org/10.22270/ajprd.v10i1.1074.

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Aromatherapy is the use of essential oils derived from herbs, flowers, and other plants for therapeutic purposes. Essential oils can enter the body through the skin or through the olfactory system. Aromatherapy is delivered in a variety of ways, including diffusers, baths, massage, and compresses. Aromatherapy is the use of essential oils derived from herbs, flowers, and other plants for therapeutic purposes. The goal of this overview was to give a summary of systematic reviews that evaluated the efficacy of aromatherapy. This overview aims to summarise and critically assess all systematic evaluations on aromatherapy as a treatment for any health problem. Our ultimate goal is to provide clearer recommendations to clinicians on the efficacy of this method.
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11

Perumpail, Brandon, Andrew Li, Umair Iqbal, Sandy Sallam, Neha Shah, Waiyee Kwong, George Cholankeril, Donghee Kim, and Aijaz Ahmed. "Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD." Diseases 6, no. 3 (September 10, 2018): 80. http://dx.doi.org/10.3390/diseases6030080.

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Our aim is to review the efficacy of various herbs and supplements as a possible therapeutic option in the treatment and/or prevention of nonalcoholic fatty liver disease (NAFLD). We performed a systematic review of medical literature using the PubMed Database by searching the chemical names of many common herbs and supplements with “AND (NAFLD or NASH)”. Studies and medical literature that discussed the roles and usage of herbs and supplements in NAFLD and nonalcoholic steatohepatitis (NASH) from inception until 20 June 2018 were reviewed. Many studies have claimed that the use of various herbs and supplements may improve disease endpoints and outcomes related to NAFLD and/or NASH. Improvement in liver function tests were noted. Amelioration or reduction of lobular inflammation, hepatic steatosis, and fibrosis were also noted. However, well-designed studies demonstrating improved clinical outcomes are lacking. Furthermore, experts remain concerned about the lack of regulation of herbs/supplements and the need for further research on potential adverse effects and herb–drug interactions. In conclusion, preliminary data on several herbs have demonstrated promising antioxidant, anti-inflammatory, anti-apoptotic, and anti-adipogenic properties that may help curtail the progression of NAFLD/NASH. Clinical trials testing the safety and efficacy must be completed before widespread can be recommended.
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12

Karole, Sarita, Sarika Shrivastava, Shefali Thomas, Bhawana Soni, Shifa Khan, Julekha Dubey, Shashi P. Dubey, Nushrat Khan, and Deepak Kumar Jain. "Polyherbal Formulation Concept for Synergic Action: A Review." Journal of Drug Delivery and Therapeutics 9, no. 1-s (February 15, 2019): 453–66. http://dx.doi.org/10.22270/jddt.v9i1-s.2339.

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Formulations restrain 2 or more than 2 herbs are called polyherbal formulation. Drug formulation in Ayurveda is based on 2 principles: Use as a single drug and use of more than one drug. The last is known as polyherbal formulation. The idea of polyherbalism is peculiar to Ayurveda even though it is tricky to explain in term of modern parameters. The Ayurvedic literature Sarangdhar Samhita tinted the idea of polyherbalism to attain greater therapeutic efficacy. Polyherbal formulation has been used all around the earth due to its medicinal and therapeutic application. It has also recognized as polyherbal therapy or herb-herb combination. The active phytochemical constituents of individual plants are inadequate to attain the desirable therapeutic effects. When polyherbal and herbo-mineral formulations combining the multiple herbs in a meticulous ratio, it will give an enhanced therapeutic effect and decrease the toxicity. The active constituents used from individual plant are inadequate to provide attractive pharmacological action. There are evidences that crude plant extracts often have greater potency rather than isolated constituents. In traditional medicine whole plants or mixtures of plants are used rather than isolated compounds. Due to synergism, polyherbalism confers some benefits which are not accessible in single herbal formulations. Polyherbal formulations express high effectiveness in numerous diseases with safe high dose. Based on the nature of the interaction, there are 2 mechanisms on how synergism acts (i.e., pharmacodynamics and pharmacokinetic). In words of pharmacokinetic synergism, the capacity of herb to ease the absorption, distribution, metabolism and elimination of the other herbs is focused. Pharmacodynamics synergism on the other hand, studies the synergistic effect when active constituents with similar therapeutic activity are targeted by diverse mechanism of action. The present review encompasses all the significant features of polyherbal formulation. Keywords: Polyherbal formulation, Ayurveda, Active constituents, Pharmacodynamics, pharmacokinetic
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13

Liu, Wei, Binbin Yang, Lu Yang, Jasmine Kaur, Calvin Jessop, Rushdi Fadhil, David Good, et al. "Therapeutic Effects of Ten Commonly Used Chinese Herbs and Their Bioactive Compounds on Cancers." Evidence-Based Complementary and Alternative Medicine 2019 (September 15, 2019): 1–10. http://dx.doi.org/10.1155/2019/6057837.

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Effective cancer therapy is one of the biggest global challenges. Conventional cancer therapies have been at the forefront of combating cancers, but more evidence showed considerable side effects, limiting their use. There are various new therapies in development, but combined approaches for treating cancer are much expected. Natural herbs had been traditionally in use for cancer therapy in most parts of the world. In this review, we have examined ten commonly used Chinese herbs that have, for centuries, shown effectiveness in treating cancers. They demonstrated the abilities to promote the apoptosis of cancer cells, inhibit their metastasis, activate the patient’s anticancer immunity, and synergistically increase the efficacy of conventional chemotherapy and radiation therapy when used in combination. Clinical experiences had proved that these herbs and their bioactive compounds were effective against a plethora of cancers through a variety of mechanisms, effectively improving patients’ quality of life without significant side effects. These advantages indicate that there are huge potentials in the development of Chinese herbs into cancer medicine as part of a promising, holistic cancer treatment modality.
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14

Haruna, N. A., O. Erhabor, T. Erhabor, and T. C. Adias. "Review of Some Herbs with Haemato-Therapeutic Properties in Use in Nigeria." Sokoto Journal of Medical Laboratory Science 6, no. 4 (February 24, 2022): 65–81. http://dx.doi.org/10.4314/sokjmls.v6i4.9.

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15

Ward, Adam. "Book Review: Tyler—s Herbs of Choice: The Therapeutic Use of Phytomedicinals." Acupuncture in Medicine 18, no. 1 (June 2000): 84–87. http://dx.doi.org/10.1136/aim.18.1.84-b.

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16

Mohammad K. Parvez and Naghma Anjum. "Liver Diseases and Adverse Reactions Induced by Medicinal Herbs and Herb-Drug Interactions." Gastroenterology & Hepatology Letters 4, no. 1 (March 28, 2022): 25–29. http://dx.doi.org/10.18063/ghl.v4i1.280.

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Integrative medicine encompasses several modalities of complementary and alternative medicine, of which the most relevant is the herbal medicine. Herbal formulations contain multiple pharmacologically active phytochemicals with isolated active compounds usually can achieve better therapeutic performance. In general, herbal medicines are believed to be more effective and safer than prescription drugs. Prescription drugs are approved and licensed only after well regulated clinical trials have been carried out, but a majority of marketed herbal products remain non-regulated without evidence of efficacy and safety. In this article, we review the potential risk of liver diseases or other organ toxicity related to herbs or the combined use of herb and drug. This article also discusses certain medicinal herbs as well as hepatotoxicy and adverse reactions induced by herb-drug interactions in liver disease patients.
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17

Asamoah-Gyadu, J. Kwabena. "Therapeutic Strategies in African Religions: Health, Herbal Medicines and Indigenous Christian Spirituality." Studies in World Christianity 20, no. 1 (April 2014): 70–90. http://dx.doi.org/10.3366/swc.2014.0072.

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The use of herbs has been the main means of curing diseases in traditional Africa and this continued through the colonial period to present times. Widely held traditional views that interpreted certain diseases as caused by supernatural agents meant that, although some ailments could be naturally caused, in most cases, shrine priests and diviners were needed to dispense herbal preparations for clients. Christian missionaries mostly – though by no means all – denounced herbal medicines as evil, looking on them as pagan because of the close relationship between herbs and agents of local divinities. At the emergence of the African independent church movement at the beginning of the twentieth century, herbal medicines acquired a sacramental value, and today they are obtained from churches and local prophets as therapeutic substances infused with spiritual power for healing. The sacramental interpretation of herbs has been extended to those obtained from prayer places and grottoes under the supervision of historic mission denominations, a phenomenon that has virtually transformed the image of herbs and herbal medicines in African therapeutic systems.
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18

Singh, Kalpana, and Arvind Kumar Srivastava. "THERAPEUTIC USES OF BUTEA MONOSPERMA." Era's Journal of Medical Research 9, no. 2 (December 2022): 218–23. http://dx.doi.org/10.24041/ejmr2022.34.

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New synthetic drugs have many side effects on health as compared to the traditional herbs used in the past.The use of medicinal plants have been en established source for a relief from illness which can be traced back over five millennia. Antibiotics are one of the life saving weapons for humans but over the past few decades these health benefits are under threat as antibiotics have become less effective and also create toxic after effects affecting human life more. The well-known medicinal herb Butea monosperma is a moderately Sizeable deciduous tree and is widely dispersed in Asian hemispheres, Burma and Sri Lanka. From time to time it has been used in traditional medicinal practices. It has been mentioned in ayurveda for medicinal uses and mythological references, also The population's health care system continues to be heavily influenced by traditional medical practises, homoeopathy, and folklore. Rural and tribal people utilise the herb extensively to treat a variety of ailments. It is known in many languages apart from its botanical name. It is called Flame of forest, Dhak, Palash etc. It has been used to treat a variety of illnesses including cancer, diabetes, dysentery, fever, jaundice, diarrhoea, and jaundice, among others. A great variety of phytochemicals, primarily flavonoids, lactones, diterpenoids, phytosterols, etc., are present in the plant's aerial portion. The need for new antimicrobial compounds from alternative sources has arisen as a result of the development of drug resistance in human infections against routinely used antibiotics. Finding possible novel chemicals for therapeutic purposes requires screening medicinal plants for antibacterial and phytochemical properties .
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Rekha, U. Vidhya. "Known data on the therapeutic use of Azadiracta indica (neem) for type 2 diabetes mellitus." Bioinformation 18, no. 2 (February 28, 2022): 82–87. http://dx.doi.org/10.6026/97320630018082.

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There has been growing interest for the therapeutic use of traditional herbs in the management of diabetes mellitus (DM) and its complications. Data shows the hypoglycemic activity of Azadirachta indica in diabetes. Therefore, it is of interest to document known data on the therapeutic use of Azadiracta indica (neem) for type 2 diabetes mellitus (T2DM).
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Gawande, Shravani, Gulab Chand Pamnani, and Sharad Bhatnagar. "Management of Oral Hygiene through Ayurveda: A Case Study." International Journal of Health Sciences and Research 11, no. 10 (October 20, 2021): 209–13. http://dx.doi.org/10.52403/ijhsr.20211027.

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Ayurveda is the ancient Indian system of health care and longevity. It involves a holistic view of man, his health and illness. Even though dentistry was not a specialised branch of Ayurveda, it is included in Shalakya Tantra. Oral diseases continue to be a major health problem worldwide. Oral health also reflects body health. For prevention and treatment of oral diseases modern medicine has limited success. Ayurveda is good alternate for that and may lead to novel preventive or therapeutic strategies for oral health. This 500 years old system of medicine not only recommends treatment with specific herbs and minerals to cure oral diseases but also recommends some daily use therapeutic procedures for the prevention of and maintenance of oral health. Recently there is grown interest in use of ayurvedic drugs for oral health and proper hygiene. Ayurveda herbs and natural products have been used for their pharmacological applications, wound healing, anti-inflammatory, antimicrobial, antioxidant properties have been proven to be safe and effective for oral disease and hygiene including various therapeutic ayurvedic procedures. Key words: Oral health, Oral diseases, Ayurvedic herbs.
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21

Ade-Ademilua, Omobolanle E. "Tyler's Herbs of Choice—The Therapeutic Use of Phytomedicinalsby Dennis V. C. Awang." Journal of Herbs, Spices & Medicinal Plants 15, no. 3 (December 10, 2009): 291. http://dx.doi.org/10.1080/10496470903379035.

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22

Sen Gupta, Rajorshi, Sandip Roy, Rajesh Bose, and Palash Mandal. "A Druggability study to Probe immunomodulatory Unani plants as active Inhibitors of Pseudotyped Particle Cell Entry." International Journal of Ayurvedic Medicine 14, no. 3 (October 3, 2023): 660–72. http://dx.doi.org/10.47552/ijam.v14i3.3765.

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Medicinal herbs, plants and their products show revolutionized effect in modern therapeutic system. Industries used their activity as antioxidant, antitoxin, antimicrobial, immune booster and many others and use them accordingly as the prime agent to produce cosmetics, food, drug synthesis etc. Unani is one of the traditional therapeutic system which use medicinal herbs mostly for making their herbal medicines. There are several immunomodulatory herbs along with their phytochemicals are present to serve their best. Bioassay is the method of analysis to find out the potency or concentration of any substance when effect on living things. Sars Cov-2 virus and its fatal outbreak is a real threat to modern society. To perform in vitro procedure to screened out small molecule inhibitors of this malicious pseudo typed particle cell entry, Dr. Whittaker's group use this bioassay system like PubChem AID: 1479144, PubChem AID: 1479149, PubChem AID: 1479150 and PubChem AID: 1494158. This in silico study is to show the potency of the phytochemicals of traditional herbs of Unani, as if inhibitors by means of machine learning with the help of WEKA. The ADMET study and molecular docking with Mpro (6lu7 chain A) is also done to test the druggability and binding affinity of the qualified phytochemicals.
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Saiyed, Falakaara, Rajesh Maheshwari, Dilsar Gohil, and Krupa Joshi. "Herbs used in cardiovascular diseases." International Journal of Ayurvedic Medicine 14, no. 1 (April 4, 2023): 42–49. http://dx.doi.org/10.47552/ijam.v14i1.3382.

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One of the many therapeutic uses for herbal medicines is the treatment of cardiovascular diseases. Since herbal medications do not require official regulatory agency approval or clinical testing before going on the market, they are less frequently proven to be safe and effective than conventional pharmaceuticals. In this review, we sum up the ongoing information on homegrown medicines, essentially utilized in cardiovascular treatment. We show how there is frequently no scientific evidence to support the use of these medications to treat cardiovascular disorders. Despite the fact that they seem to affect organic cycles connected with the cardiovascular framework, there is little data on the restorative impacts of the majority of these herbs. Concerns are raised by the potential for medication contamination or drug substitution with other prescriptions, as well as by related negative effects like a higher risk of drug interactions. Doctors should review any potential benefits and drawbacks of their patients' use of herbal remedies in every situation. Keywords: Herbs, Medicine, Cardiovascular, Disease, Potential benefits, Drawbacks.
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Vilímek, Vítězslav. "Denominations of Herbs in Těšín Silesia motivated by their therapeutic effects." Slavic Almanac, no. 3-4 (2020): 270–88. http://dx.doi.org/10.31168/2073-5731.2020.3-4.3.03.

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This study focuses on the names of medicinal plants which are used in the linguistic area of Těšín Silesia and which have been derived from their eff ects known in folk human and veterinary medicine. The etymol-ogy of the names of these plants was transparent to the average speaker of the language and acted as a clear guide on how to use them. It is therefore a suitable source of ethnolinguistic knowledge. We identify four typical types of motivation: the organ or part of body for which the plant is used; the disease against which the plant is used; the eff ect; the person or animal for whose treatment the plant is used. Each type is documented using specifi c examples and aided by analyses of the origin of the name of the plant and its therapeutic use as it is known in Těšín Silesia. In interesting cases, comparison with contemporary Czech and other Slavic languages is also carried out.
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Sumer, Peter De Roux, Bimal Debbarma, Kmensiful Binan, Waibiangki Lyngdoh, and Loushambam Samananda Singh. "Therapeutic Insights into Anti-Inflammatory Activities Derived from Medicinal Plants." UTTAR PRADESH JOURNAL OF ZOOLOGY 44, no. 23 (November 20, 2023): 95–108. http://dx.doi.org/10.56557/upjoz/2023/v44i233769.

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Many synthetic drugs previously considered for treating inflammatory conditions have lost favor due to their potential side effects and adverse outcomes, along with their proven safety concerns for human use. In recent years, herbal remedies have gained popularity as an alternative treatment for a wide range of human ailments. Herbs possessing anti-inflammatory properties have attracted significant attention because they do not have many of the drawbacks associated with synthetic medications. This review aims to provide a comprehensive overview of recently discovered anti-inflammatory compounds falling into various classes of plant constituents, including alkaloids, glycosides, terpenoids, steroids, polyphenolic compounds, and those derived from marine organisms, fungi, and algae. Furthermore, it explores the broader perspective of potential interactions between herbal and synthetic drugs, associated adverse effects, and clinical studies examining the anti-inflammatory properties of herbs.
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Soyata, Amelia, Aliya Nur Hasanah, and Taofik Rusdiana. "Interaction of Warfarin with Herbs Based on Pharmacokinetic and Pharmacodynamic Parameters." Indonesian Journal of Pharmaceutics 2, no. 2 (June 5, 2020): 69. http://dx.doi.org/10.24198/idjp.v2i2.27289.

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Warfarin is an oral anticoagulant that has been widely used and has strong efficacy, but the use of warfarin is still a concern because of its narrow therapeutic index which cause interactions when co-administration with drugs, herbs or food. This interaction can affect the pharmacokinetics and pharmacodynamics of warfarin and the most fatal effect from warfarin interactions is bleeding. In this review article data on warfarin-herbs interactions were collected based on pharmacokinetic parameters (AUC0-∞, Cmax, T1/2, Cl/F, and V/F), while pharmacodynamic parameters (International normalized ratio (INR), platelet aggregation, AUC INR and Protombine Time). As a result some herbs had significant interactions with warfarin. Herbs that affect warfarin pharmacokinetic were Danshen gegen, echinacea, St. John's wort and caffeine and herbs that affect pharmacodynamic were policosanol, Ginkgo biloba, cranberry, St. John's wort, ginseng, pomegranate, Psidium guajava and curcumin, so co-administration warfarin with herbs need to be considered.Keywords: Warfarin, Interactions, Herbs, Pharmacokinetics, Pharmacodynamics
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Kher, Jimisha Dharmendrasinh, and Hemangiben Hasmukhbhi Patel. "A review on potential anti-diabetic herbs and polyherbal formulations concept." Indian Journal of Pharmacy and Pharmacology 10, no. 1 (March 15, 2023): 7–11. http://dx.doi.org/10.18231/j.ijpp.2023.003.

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Multifactorial diseases, for diabetes develop various complication like hepatic toxicity, retinopathy, neuropathy, nephropathy and immunodeficiency etc. Numerous medicinal herbs have been used for the diabetes mellitus in traditional systems of medicine worldwide as they are a great source of phytochemical constituents and many of them are known to be effective against diabetes. Medicinal herbs with antidiabetic activities are being more desired, to lesser side effect and low cost. The efficacy of antihyperglycemic herbs is achieved by increasing insulin secretion, enhancing glucose uptake, activate GLP and inhibiting glucose production. The antidiabetic herbs contains many phytochemical constituents they single herb use produce mild effect when the combining of two — three herbs which having different chemical constituent and pharmacological action and produce synergistic effect and avoid repeated dose and achieve the efficacies therapeutic effec.
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Djunaedi, Mochamad, and Syed Azhar Syed Sulaiman. "THE PHARMACIST’S ASSESSMENT ON PATIENTS WHO CONSUME SUPPLEMENTS AND HERBAL WHILE UNDERGOING WARFARIN THERAPY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 13 (April 26, 2018): 49. http://dx.doi.org/10.22159/ajpcr.2018.v11s1.26566.

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Objective: The supplements and herbal medicines used should be monitored in a patient taking warfarin, to achieve the goal of warfarin anticoagulation. This study aims to evaluate the impacts of the supplement and the herbs used on the performance of anticoagulation.Methods: There were 214 eligible patients for having CHADS2 score >2 registered at warfarin-medication therapy adherence clinic coordinated by Cardiac Hospitals in Malaysia in 2012 included for this study. They have been assessed using a trained pharmacist regarding the safety and efficacy of warfarin as per guideline. Results: Supplements and herbs are commonly used by the patient (61.2%) who is taking warfarin. Some patients (23%) have decided not to use or stop using it after being consulted by the pharmacist. Some are even starting to use it (37%). Effects of supplements and herbal medicines were found to decrease in the International normalized ratio (INR) reading as 33%, increasing in 37% the INR reading. Further, pharmacist action is to do a dose adjustment to reach INR in the therapeutic range 2.0–3.0. Supplements consumed as categorized as phytomedicine-containing herbs, such as Omega3 and glucosamine. Whereas herbs used as beetle leaves and the product of extracted herbs, for example, Gingko biloba, Cordyceps, etc. Conclusion: Monitoring by pharmacist is needed to achieve the goal of warfarin as well as to minimize the INR out of therapeutic. The use of herbal and supplement is found to be a factor contributes to the performance of anticoagulation control which has been successfully achieved 71.2%.
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Mochtar, Nuniek Nizmah F., Eko Mugiyanto, Wirasti Wirasti, Vanesa Maharani, Novel Umarella, Hilda Fitria Wulandari, St Rahmatullah, et al. "Indonesian anti-inflammation herbs mechanism: mini review." Jurnal Ilmiah Kesehatan 16, no. 2 (September 4, 2023): 64–75. http://dx.doi.org/10.48144/jiks.v16i2.1453.

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This mini-review aims to provide an overview of some commonly used anti-inflammatory herbs in Indonesia. Inflammation is a complex physiological response that plays a role in various diseases, and herbal remedies have been used traditionally in Indonesian culture for their potential anti-inflammatory properties. We utilize Portal Garuda as the primary database for searching herbs with anti-inflammatory activity using the keyword "anti-inflamasi”. The selected herbs discussed in this review include turmeric (Curcuma longa), ginger (Zingiber officinale), clove (Syzygium aromaticum), and cinnamon (Cinnamomum sp.). These herbs have been reported to possess anti-inflammatory effects through various mechanisms, such as inhibition of pro-inflammatory enzymes and cytokines, antioxidant activity, and modulation of immune responses. Moreover, these herbs have also demonstrated safety profiles in traditional use. However, further scientific research is needed to elucidate the specific bioactive compounds responsible for their anti-inflammatory effects and to determine the optimal dosages and formulations for therapeutic use. The exploration of Indonesian anti-inflammatory herbs could contribute to the development of natural and affordable options for managing inflammatory conditions, complementing conventional treatments, and promoting overall health and well-being.
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Ge, Beikang, Zhen Zhang, and Zhong Zuo. "Updates on the Clinical Evidenced Herb-Warfarin Interactions." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–18. http://dx.doi.org/10.1155/2014/957362.

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Increasing and inadvertent use of herbs makes herb-drug interactions a focus of research. Concomitant use of warfarin, a highly efficacious oral anticoagulant, and herbs causes major safety concerns due to the narrow therapeutic window of warfarin. This paper presents an update overview of clinical findings regarding herb-warfarin interaction, highlighting clinical outcomes, severity of documented interactions, and quality of clinical evidence. Among thirty-eight herbs, Cannabis, Chamomile, Cranberry, Garlic, Ginkgo, Grapefruit, Lycium, Red clover, and St. John’s wort were evaluated to have major severity interaction with warfarin. Herbs were also classified on account of the likelihood of their supporting evidences for interaction. Four herbs were considered ashighly probableto interact with warfarin (level I), three were estimated asprobable(level II), and ten and twenty-one werepossible(level III) anddoubtful(level IV), respectively. The general mechanism of herb-warfarin interaction almost remains unknown, yet several pharmacokinetic and pharmacodynamic factors were estimated to influence the effectiveness of warfarin. Based on limited literature and information reported, we identified corresponding mechanisms of interactions for a small amount of “interacting herbs.” In summary, herb-warfarin interaction, especially the clinical effects of herbs on warfarin therapy should be further investigated through multicenter studies with larger sample sizes.
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Kelber, Olaf, Rudolf Bauer, and Wolfgang Kubelka. "Phytotherapy in Functional Gastrointestinal Disorders." Digestive Diseases 35, Suppl. 1 (2017): 36–42. http://dx.doi.org/10.1159/000485489.

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Background: Phytotherapy is an important therapeutic option in functional gastrointestinal diseases (FGID). It has a large tradition, with different approaches in different regions of the world, some of which have made their way into modern evidence-based medicine (EBM). Summary: Taking into account the number of herbs in use, and also the cumulated scientific evidence on them, FGID are possibly the most important indication in phytotherapy. This does not only apply for European phytotherapy, but also for other regions, such as Asia. Within European phytotherapy, herbs active in FGID are usually classified according to their main active constituents and their activities. Typically, the herbs used in FGID are grouped into amara, aromatica, amara aromatica combining both properties, herbs stimulating gastric secretion, herbs containing spasmolytic and carminative essential oils or spasmolytic alkaloids, mucilaginosa soothing the mucosa, and flavonoid containing drugs with anti-inflammatory properties. In phytotherapy, different plants are frequently combined to maximize effectiveness and specificity of action. Very potent combination products can be developed when the mechanisms of action of the combination partners are complementary. This approach can be demonstrated by the example of STW 5. For this herbal combination product, therapeutic efficacy in FGID has been clinically proven according to the highest standards of EBM. This example also underlines that modern rational phytotherapy is definitely part of modern EBM. Key Messages: FGID is one of the most important indications in phytotherapy and rationally combined herbal preparations are established evidence-based therapeutic options.
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Thamanna, P., and Prasanth M. L. Lal. "Comparative review on polyherbal and monoherbal cosmetic formulations." i-manager's Journal on Chemical Sciences 3, no. 1 (2023): 32. http://dx.doi.org/10.26634/jchem.3.1.19379.

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This comparative review explores the characteristics and benefits of polyherbal and monoherbal cosmetic formulations. Formulations containing two or more herbs are called polyherbal formulations. Drug formulation in Ayurveda is based on the use of a single drug or more than one drug. A monoherbal formulation contains only one herb. The problem of polyherbal formulation occurs due to sources and manufacturing processes, patients, drug-herb interaction, toxicity, and improper manufacturing. Polyherbal formulations mean the use of more than one herb in a therapeutic preparation. In Ayurveda, multiple herbs are used in the treatment of illness.
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Patil, Aarti, and Sury Pratap Singh. "Study on the Therapeutic Properties of Herbs and Their Utilization in the Development of Value-Added Products: A Review." Journal of Scientific Research and Reports 29, no. 7 (June 17, 2023): 71–83. http://dx.doi.org/10.9734/jsrr/2023/v29i71761.

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India has the largest population of cattle in the world and also ranks first in consumption considering it as having a huge demand for dairy and value-added dairy products. A wide range of dairy products is already available in the market like butter, cheese, labneh, ice cream, buttermilk, custard, etc. Yogurt is one of the oldest consumed dairy products with several benefits as it contains various microorganisms such as Lactic acid bacteria, Lactobacillus spp. and Streptococcus spp. which ferment the product and it helps in improving the nutritional value of the product. Yogurt contains a rich source of B vitamins, lactose, proteins, and minerals. To enhance its nutritional value herbs and fruits can be added to it. Herbs are a type of plant whose leaves and seeds have a wide range of use in medicines, adding flavor, cooking, etc. Herbs are anti-inflammatory, have antioxidants, boost the immune system, and have several other health benefits. Different types of herbs and their health benefits were studied such as Ashwagandha, Arjuna, Cinnamon, Sage, Aloe vera, Tulsi, and Peppermint. Fruits are added to dairy products to enhance their flavor and nutritional value. Fruits are a good source of vitamins and minerals. In this review paper, we discuss the nutritional prospects of yogurt supplemented with herbs.
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Jiang, T. Alan. "Health Benefits of Culinary Herbs and Spices." Journal of AOAC INTERNATIONAL 102, no. 2 (March 1, 2019): 395–411. http://dx.doi.org/10.5740/jaoacint.18-0418.

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Abstract Spices and herbs have been in use for centuries both for culinary and medicinal purposes. Spices not only enhance the flavor, aroma, and color of foodand beverages, but they can also protect from acuteand chronic diseases. More Americans are considering the use of spices and herbs for medicinal and therapeutic/remedy use, especially for various chronicconditions. There is now ample evidence that spicesand herbs possess antioxidant, anti-inflammatory, antitumorigenic, anticarcinogenic, and glucose- and cholesterol-lowering activities as well as properties that affect cognition and mood. Research over the past decade has reported on the diverse range of health properties that they possess via their bioactive constituents, including sulfur-containing compounds, tannins, alkaloids, phenolic diterpenes, andvitamins, especially flavonoids and polyphenols. Spices and herbs such as clove, rosemary, sage, oregano, and cinnamon are excellent sources of antioxidants with their high content of phenolic compounds. It is evident that frequent consumption of spicy foods was also linked to a lower risk of death from cancer and ischemic heart and respiratory system diseases. However, the actual role of spicesand herbs in the maintenance of health, specifically with regards to protecting against the development of chronic, noncommunicable diseases, is currently unclear.This review highlights potential health benefits ofcommonly used spices and herbs such as chili pepper, cinnamon, ginger, blackpepper, turmeric, fenugreek, rosemary, and garlic.
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Praseetha, P. K., and K. Sreedevy. "An Analytical Observational Study to Determine the Antibacterial and Antioxidant Properties of Dashapushpam, Ten Medicinal Plants." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 13 (June 13, 2024): 262–68. http://dx.doi.org/10.56557/upjoz/2024/v45i134152.

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A collection of ten revered herbs known with their traditional and therapeutic significance is known as Dashapushpam in the Kerala state of India, and particularly utilized by Keralites on the onsets of the monsoons. The current research aims to showcase the antibacterial and antioxidant properties of these ten herbs. The antibacterial efficacy was assessed against Gram-negative Escherichia coli and Gram-positive Bacillus subtilis using the agar-gel diffusion method. All extracts exhibited varying degrees of activity against these test organisms, with their effectiveness compared to the standard antibiotic amoxicillin. Additionally, the study evaluated the antioxidant potential of the Dashapushpam herbs through the nitric oxide scavenging assay, revealing different levels of antioxidant activity among the plants. These findings support the potential use of these ten herbs in medicinal applications as anti-infective agents.
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Lin, Sheng-Chieh, Li-Shian Shi, and Yi-Ling Ye. "Advanced Molecular Knowledge of Therapeutic Drugs and Natural Products Focusing on Inflammatory Cytokines in Asthma." Cells 8, no. 7 (July 5, 2019): 685. http://dx.doi.org/10.3390/cells8070685.

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Asthma is a common respiratory disease worldwide. Cytokines play a crucial role in the immune system and the inflammatory response to asthma. Abnormal cytokine expression may lead to the development of asthma, which may contribute to pathologies of this disease. As cytokines exhibit pleiotropy and redundancy characteristics, we summarized them according to their biologic activity in asthma development. We classified cytokines in three stages as follows: Group 1 cytokines for the epithelial environment stage, Group 2 cytokines for the Th2 polarization stage, and Group 3 cytokines for the tissue damage stage. The recent cytokine-targeting therapy for clinical use (anti-cytokine antibody/anti-cytokine receptor antibody) and traditional medicinal herbs (pure compounds, single herb, or natural formula) have been discussed in this review. Studies of the Group 2 anti-cytokine/anti-cytokine receptor therapies are more prominent than the studies of the other two groups. Anti-cytokine antibodies/anti-cytokine receptor antibodies for clinical use can be applied for patients who did not respond to standard treatments. For traditional medicinal herbs, anti-asthmatic bioactive compounds derived from medicinal herbs can be divided into five classes: alkaloids, flavonoids, glycosides, polyphenols, and terpenoids. However, the exact pathways targeted by these natural compounds need to be clarified. Using relevant knowledge to develop more comprehensive strategies may provide appropriate treatment for patients with asthma in the future.
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Fathinezhad, Zohre, Robert D. E. Sewell, Zahra Lorigooini, and Mahmoud Rafieian-Kopaei. "Depression and Treatment with Effective Herbs." Current Pharmaceutical Design 25, no. 6 (June 12, 2019): 738–45. http://dx.doi.org/10.2174/1381612825666190402105803.

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Depression is a common psychiatric disease and one of the main causes of disability worldwide. In spite of certain developments in this field, chemical and synthetic drugs used for the treatment of depression disrupt the treatment process due to numerous side effects and high cost. Today, the goal of using a potential method for treating depression involves the use of medicinal and phytochemical plants, which have many therapeutic benefits. Studies have shown that medicinal plants affect the nervous system and exert antidepressant effects in various ways, including synaptic regulation of serotonin, noradrenaline and dopamine, and inflammatory mediators. In this study, depression as well as the factors and mechanisms involved in its development are first addressed, and then medicinal plants effective in the treatment of depression along with their mechanisms of actions are reported.
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Mueller, Larissa Pires, Dioelen Virginia Borges Souza de Aquino Coelho, Laís Chancare Garcia, Lígia Harumi Vilela Bartnick Tanaka, Thais Gimenes Bachega, Altair Meirelles de Sousa Maia, Vinício Guimarães Freitas, Luiz Fernando Benazet, Cláudio Rodrigo Nogueira, and Silvia Aparecida Oesterreich. "The Aristolochia (Aristolochiaceae) genus: therapeutic properties, biological effects and toxicity." Research, Society and Development 11, no. 11 (August 23, 2022): e293111133504. http://dx.doi.org/10.33448/rsd-v11i11.33504.

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The Brazilian flora harbors extensive plant biodiversity with the possibility of therapeutic use. In this context, the genus Aristolochia is widely used in folk medicine. From this perspective, the study aims to demonstrate important characteristics of these vegetables in the current literature. It was observed that the genus has promising medicinal properties that are directly related to its biological and chemical composition. However, it is notable that more research is needed to guide the safe use and encourage the synthesis of new pharmaceutical products derived from these herbs.
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Sparreboom, Alex, Michael C. Cox, Milin R. Acharya, and William D. Figg. "Herbal Remedies in the United States: Potential Adverse Interactions With Anticancer Agents." Journal of Clinical Oncology 22, no. 12 (June 15, 2004): 2489–503. http://dx.doi.org/10.1200/jco.2004.08.182.

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Purpose Interest in the use of herbal products has grown dramatically in the Western world. Recent estimates suggest an overall prevalence for herbal preparation use of 13% to 63% among cancer patients. With the narrow therapeutic range associated with most anticancer drugs, there is an increasing need for understanding possible adverse drug interactions in medical oncology. Methods In this article, a literature overview is provided of known or suspected interactions of the 15 best-selling herbs in the United States with conventional allopathic therapies for cancer. Results Herbs with the potential to significantly modulate the activity of drug-metabolizing enzymes (notably cytochrome P450 isozymes) and/or the drug transporter P-glycoprotein include garlic (Allium sativum), ginkgo (Ginkgo biloba), echinacea (Echinacea purpurea), ginseng (Panax ginseng), St John's wort (Hypericum perforatum), and kava (Piper methysticum). All of these products participate in potential pharmacokinetic interactions with anticancer drugs. Conclusion It is suggested that health care professionals and consumers should be aware of the potential for adverse interactions with these herbs, question their patients on their use of them, especially among patients whose disease is not responding to treatments as expected, and urge patients to avoid herbs that could confound their cancer care.
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Meneses, Keila Fernanda Pacheco, Cinthya Costa Lopes, Gabriel José Feitosa Belfort, Edson Abreu Belfort, Patrícia Costa Santos Alves, Maira Silva Ferreira, Alamgir Khan, and Raquel Maria Trindade Fernandes. "Phytoterapic products marketed in free fairs of São Luís-MA: a therapeutic analysis." Caderno Pedagógico 21, no. 6 (June 5, 2024): e4084. http://dx.doi.org/10.54033/cadpedv21n6-032.

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Historically, medicinal herbs have been playing an essential role in the development of novel medications as well as the manufacturing of traditional herbal remedies. Brazil is among the nations in which commercialization of medicinal herbs is becoming more prevalent. This growth is attributed to the wealthy diversity of plants as well as the low cost of the therapy, as demonstrated by the fact that 82% of Brazilians use medicinal herbs on a regular basis to safeguard their good health. Utilizing qualitative as well as quantitative approaches, the primary objective of the investigation was to examine the way the aforementioned goods were being traded in São Luís marketplaces on the streets. According to information from stallholders, 86 products have been identified, the most of which were in oil form. These products have a variety of uses, including antiseptic, anti-inflammatory, and expectorant qualities. The five most popular products in terms of sales and demand have been identified according to the samples that had been collected. These consist of andiroba oil, copaiba oil, pequi oil, castor oil, and the annatto syrup. Without knowing the products' origins, the individuals being interviewed reported that they were merely selling them. The vast majority of the products (≈ 80%) did not have labels specifying indications, how to use, contraindications, origin, or validity and, for the few that did, the information was incomplete. The study demonstrated that although the utilization of medicinal plants is an essential component of conventional medicine, merchants continue to have a deficiency of technical knowledge that put human health at risk through carelessness or even inappropriate usage of these products.
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Hashmi, Arshee. "PROPHETIC MEDICINE AND HERBS IN ORAL CARE A REVIEW OF LITERATURE." International Journal of Islamic and Complementary Medicine 5, no. 1 (March 10, 2024): 7–16. http://dx.doi.org/10.55116/ijicm.v5i1.69.

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Prophetic medicine comprises the teaching of the prophet Mohammad with regards to nutrition, hygiene, sickness, cure and prevention of the ailments. “Whenever the Prophet (ﷺ) would visit an ill person, he would said:‘[O Allah,] make the harm go away, Lord of mankind, and heal him, You are the Healer, there is no healing except your healing, a healing that does not leave any sickness. Healing with the Medicine of the Prophet (PBUH) is the remedy for well-being, good health and soul. Prophetic medicines promote healing, prevention and cure of ailments. The review article is an effort to explore detailed analysis of prophetic medicines and natural herbs in oral care. The article is focused on the uses of miswak, honey, black seed, olives, senna and idhkhir for oral therapeutic uses. The studies, experiments and research have demonstrated that the prophetic medicines and herbs provide benefits in oral care. However, the research conducted on some herbs are limited to in vitro studies, thus further studies are required to be carried out on animals or humans to achieve accurate results. Furthermore, other herbs mentioned in prophetic medicines like tannumah (aloes), daghabis (dill seed), dates, cortus, need to be explored and further studied for therapeutic use in oral care.
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Sharma, Hari M. "Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. James E. Robbers , Varro E. Tyler." Quarterly Review of Biology 74, no. 3 (September 1999): 370. http://dx.doi.org/10.1086/393241.

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Pulipaka, Shankaraiah, Ashish Suttee, M. Ravi Kumar, and Pavani Sriram. "Effective use of Phytotherapy in the Management of Diabetes by Plant-based Medicine: A Review." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 13, no. 03 (September 1, 2022): 15–23. http://dx.doi.org/10.25258/ijpqa.13.3.20.

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>Objective: Herb-based restorative items have been recognized since prehistoric times, and a few therapeutic herbs and their active constituents were utilized for controlling diabetes in numerous people around the world. However, minimal toxicological data exist concerning conventional anti-diabetic plants. Several synthetic oral hypoglycemic agents are the essential treatment types for diabetes. As it may, apparent symptoms of similar medicament are the primary explanation behind an extended number of individuals looking for voluntary remedies that may have less severe or no reactions. This paper attempted to list the herbs with anti-diabetic and associated advantageous impacts from various parts of the world and polyherbal extractions. These herb’s impacts can defer diabetic difficulties and give a more basis of antioxidants they are acknowledged for preventing/postponing diverse ailing states. The literature review was carried out in a scientific database using diabetes, anti-diabetic agents, and phytotherapy to manage diabetes by plant-based medicine as the keywords. To overcome the research gap, optimizing phytotherapy in the management of diabetes by plant-based medicine is regarded as a good target for anti-diabetic agents to design the treatment of type 2 diabetes mellitus (T2DM). Diabetes is the world’s quick aborning emergent, and this disorder’s information will increase similar additional acceptable therapies. Traditional plant medicines are used throughout the world for diabetes. Therefore, studying such drugs will provide the natural key to unlocking a scientist in the future.The review focused on alternative medicine to cure kinds of diabetes problems using herbal preparation.
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SHAHIDAN, WAN NAZATUL SHIMA, TUAN NADRAH NAIM TUAN ISMAIL, and KANNAN THIRUMULU PONNURAJ. "Malaysian Herbs in Contraception: Public Perception." Jurnal Sains Kesihatan Malaysia 20, no. 1 (January 1, 2022): 129–37. http://dx.doi.org/10.17576/jskm-2022-2001-12.

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Medicinal plants have been used in Malaysia for a long time ago. These plants have been marketed as herbal product and used in the traditional healthcare system because of its positive therapeutic effects. This paper discusses particularly several types of Malaysian herbs that are traditionally used for contraception and scientific studies related to its pharmaceutical properties showing its use among the public for its anti-fertility effects. Even though several methods of contraception have been promoted for family planning, yet, the perception of the public on the usage of synthetic steroidal contraceptives due to its serious adverse effects has made them focus on indigenous plants. Contraceptives drug-containing oestrogen and progesterone have proven to be effective and popular, However, the side effects of these drugs have sparked the idea of scientists to develop newer molecules from medicinal plants. Therefore, it is necessary to investigate in-depth qualitative research on conceptions and concerns about traditional contraceptive methods using herbal ingredients among Malaysians.
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Pandey, Rajesh, and Surendra Singh. "Spirulina and Herbal Combination on Metabolic Alterations of Cardiovascular Diseases (CVDs)." International Journal of Research and Review 9, no. 3 (March 16, 2022): 308–17. http://dx.doi.org/10.52403/ijrr.20220334.

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Cardiovascular diseases (CVD) and metabolic changes are among the foremost public health concerns that have been accounted in people alive with cardio infections. Issues contributing to heart metabolic condition in CVD take in body fat allocation, dyslipidemia, insulin conflict, cardiovascular dysfunction and swelling. CVD have appeared as a main public health trouble and impose a rising load on the health care system. Increased coronary heart disease risk and conventional risk issues contribute to elevate the risk. They stay the foremost roots of morbidity and mortality globally. The employ of medicinal herbs keep on to be an alternative action move toward for some infections including CVDs. Presently, there is an unprecedented constrain for use of herbal preparations in current medicinal systems. This drive is powered through several aspects that are cost-effective therapeutic assure contrast to standard therapies with safety. Consequently, public awareness should be raised about medicinal herbs, toxicity, potentially life threatening, and possible herb-drug interactions. Present article highlighted the significant effect of Spirulina and other herbs supplementation individual and in combination. Many attempts on medicinal herbs in order to use in CVD treatments were reported. We overview the use of these herbs having ethno pharmacological curative potentials and medicinal properties against CVDs are reviewed. The employment of a range of herbs in the context of CVDs, such as myocardial infarction, hypertension, peripheral vascular diseases, coronary heart disease, cardiomyopathies, and dyslipidemias has been reviewed, analyzed, and significantly discussed. Keywords: Spirulina, herbal medicine, cardiovascular diseases, atherosclerosis, hypertension, medicinal plants, antioxidants, oxidative stress.
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Fu, Li-Min, and Ju-Tzu Li. "A Systematic Review of Single Chinese Herbs for Alzheimer's Disease Treatment." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–8. http://dx.doi.org/10.1093/ecam/nep136.

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The objectives here are to provide a systematic review of the current evidence concerning the use of Chinese herbs in the treatment of Alzheimer's disease (AD) and to understand their mechanisms of action with respect to the pathophysiology of the disease. AD, characterized microscopically by deposition of amyloid plaques and formation of neurofibrillary tangles in the brain, has become the most common cause of senile dementia. The limitations of western medications have led us to explore herbal medicine. In particular, many Chinese herbs have demonstrated some interesting therapeutic properties. The following databases were searched from their inception: MEDLINE (PUBMED), ALT HEALTH WATCH (EBSCO), CINAH and Cochrane Central. Only single Chinese herbs are included. Two reviewers independently extracted the data and performed quality assessment. The quality assessment of a clinical trial is based on theJadadcriteria. Seven Chinese herbs and six randomized controlled clinical trials were identified under the predefined criteria.Ginkgo biloba, Huperzine A (Lycopodium serratum) and Ginseng have been assessed for their clinical efficacy with limited favorable evidence. No serious adverse events were reported. Chinese herbs show promise in the treatment of AD in terms of their cognitive benefits and more importantly, their mechanisms of action that deal with the fundamental pathophysiology of the disease. However, the current evidence in support of their use is inconclusive or inadequate. Future research should place emphasis on herbs that can treat the root of the disease.
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Das, Madhumita, and P. B. Kar Mahapatra. "LITERARY REVIEW OF THREE HERBS (BRAHMI, SANKHAPUSPI, JATAMANSHI) USE FOR PROMOTION OF MEDHA (INTELLECT)." International Ayurvedic Medical Journal 9, no. 10 (October 15, 2021): 2450–57. http://dx.doi.org/10.46607/iamj2509102021.

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Health is a complete state of physical, psychological, social, and spiritual well-being. Every human being will reach the ultimate success of their life when they are full of Intellect. So, Ayurveda has been playing a great role in providing health to personal and the public from the very inception of human civilization. From the ancient era, many herbs were mentioned in Ayurveda which help in the promotion of the intellect of human beings. Acharya Charaka has mentioned in Charaka Chikitsa Rasayana Chapter some Medhya Rasayana herbs which help to in- crease our Medha (intellect), Improve Grahana Sakti (power of perception), Smriti (power of recalling), Agni (power of digestion and metabolism), Varna (complexion) and Svara (voice). Medhya Rasayana drugs improve mental faculties and mental function with the help of their properties. The present article reviewed different Ayur- vedic Classics of Samhita Period, Sangraha Period, Nighantu Period, Late Modern Period and of Contemporary Period to collect the information’s regarding the pharmacodynamics of drugs and their therapeutic uses to furnish here within a methodical manner for better understanding of their therapeutic efficacy of this drug by the scholars of this field. Through the review of the literature regarding Brahmi (Bacopa monnieri), Sankhapuspi (Convolvulus pluricaulischois), Jatamanshi (Nardostachys jatamansi) it has been observed that these drugs are potent Medhya(intellect) with the properties as mentioned in this article. Keywords: Medha, Intellect, Brahmi, Sankhapuspi, Jatamanshi.
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Zhang, Shaofan, Li Shi, Dan Mao, Weijun Peng, Chenxia Sheng, Chenchen Ding, Fengxia Lin, Caiyun Lei, and Sifang Zhang. "Use of Jianpi Jiedu Herbs in Patients with Advanced Colorectal Cancer: A Systematic Review and Meta-Analysis." Evidence-Based Complementary and Alternative Medicine 2018 (2018): 1–13. http://dx.doi.org/10.1155/2018/6180810.

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Objective. To systematically review the effect of invigorating Pi and detoxification (Jianpi Jiedu, (JPJD)) herbs in advanced colorectal cancer (CRC) patients receiving chemotherapy. Methods. Three English and four Chinese databases were searched. Literature was screened by EndNote X7 and data were analyzed by RevMan 5.2. Results. This review comprised 12 randomized clinical studies of 701 patients. The results showed that JPJD herbs improved the therapeutic effect on Chinese medicine symptoms [risk ratio (RR) = 1.59; 95% confidence interval (CI): 1.35~1.88] and Karnofsky performance score [RR = 2.07; 95% CI: 1.52~2.82] for advanced CRC patients receiving chemotherapy, lowered the Chinese medicine symptoms’ score [weighted mean difference = −2.44; 95% CI: −3.23~−1.64], reduced the incidence of nausea and vomiting [RR = 0.23; 95% CI: 0.11~0.49], improved platelet at toxicity grades III-IV [odds ratio = 0.29; 95% CI: 0.12~0.74] and I–IV [RR = 0.65; 95% CI: 0.51~0.82], and improved white blood cell at toxicity grades III-IV [RR = 0.37; 95% CI: 0.23~0.58] and I–IV [RR = 0.69; 95% CI: 0.60~0.79]. However, the results showed no significant effect on tumor response. Conclusion. JPJD herbs can improve quality of life, relieve symptoms, and reduce adverse events of advanced CRC patients receiving chemotherapy.
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FM, Bhat. "Phytochemical and Pharmacological Studies of Traditionally used Herbal Plants and their Potential Applications in Nutraceutical Formulations." Journal of Natural & Ayurvedic Medicine 7, no. 4 (October 5, 2023): 1–17. http://dx.doi.org/10.23880/jonam-16000422.

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Herbal plants are being used for therapeutic purposes to cure diverse forms of diseases since centuries ago. Many medicinal therapists across the world utilize these herbs for the treatment of diseases, such as ayurveda and traditional Chinese medicine. The use of herbal based medicines considered as safe with no side effects have increased at an alarming pace as compared to synthetic drugs globally. Medicinal herbs have been validated to eradicate the core of diseased ailments irrespective of age group and are having lesser chances of developing adverse effects due to chemical interactions and microbial resistance as induced by most of the synthetic drugs. Considering the multiple biological activities, which are beneficial for healthy functioning of human body including prevention of cancers, inflammations, infections, antiseptics, antimicrobial, antidiarrheal, antioxidants and innumerable healing characteristics. In this study, we assessed the potential benefits and bioactive compounds present in diverse ranges of medicinal herbs, so that it could provide a valid source for practitioners and those interested in formulation of health promoting supplements and nutraceuticals. The chemical composition of medicinal herbs not only enables a researcher to enhance health by curing a specific disease but also to preserve a formulated food product with natural based remedies. Products developed from herbal combinations have been found to reduce toxicity in human body along with improving efficacy.
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FM, Bhat. "Phytochemical and Pharmacological Studies of Traditionally Used Herbal Plants and their Potential Applications in Nutraceutical Formulations." International Journal of Pharmacognosy & Chinese Medicine 7, no. 2 (July 12, 2023): 1–18. http://dx.doi.org/10.23880/ipcm-16000262.

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Herbal plants are being used for therapeutic purposes to cure diverse forms of diseases since centuries ago. Many medicinal therapists across the world utilize these herbs for the treatment of diseases, such as ayurveda and traditional Chinese medicine. The use of herbal based medicines considered as safe with no side effects have increased at an alarming pace as compared to synthetic drugs globally. Medicinal herbs have been validated to eradicate the core of diseased ailments irrespective of age group and are having lesser chances of developing adverse effects due to chemical interactions and microbial resistance as induced by most of the synthetic drugs. Considering the multiple biological activities, which are beneficial for healthy functioning of human body including prevention of cancers, inflammations, infections, antiseptics, antimicrobial, antidiarrheal, antioxidants and innumerable healing characteristics. In this study, we assessed the potential benefits and bioactive compounds present in diverse ranges of medicinal herbs, so that it could provide a valid source for practitioners and those interested in formulation of health promoting supplements and nutraceuticals. The chemical composition of medicinal herbs not only enables a researcher to enhance health by curing a specific disease but also to preserve a formulated food product with natural based remedies. Products developed from herbal combinations have been found to reduce toxicity in human body along with improving efficacy
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