Academic literature on the topic 'Heteroaromatic rings'

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Journal articles on the topic "Heteroaromatic rings"

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Pitt, William R., David M. Parry, Benjamin G. Perry, and Colin R. Groom. "Heteroaromatic Rings of the Future." Journal of Medicinal Chemistry 52, no. 9 (2009): 2952–63. http://dx.doi.org/10.1021/jm801513z.

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Doerksen, Robert J., and Ajit J. Thakkar. "Bond orders in heteroaromatic rings." International Journal of Quantum Chemistry 90, no. 2 (2002): 534–40. http://dx.doi.org/10.1002/qua.998.

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Orita, Akihiro, Fangguo Ye, Govindarajulu Babu, Tomohiro Ikemoto, and Junzo Otera. "Double elimination protocol for the synthesis of arylene ethynylenes containing heteroaromatic rings." Canadian Journal of Chemistry 83, no. 6-7 (2005): 716–27. http://dx.doi.org/10.1139/v05-038.

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The double elimination reaction of β-substituted sulfones offers a versatile strategy for synthesis of arylene ethynylene kits containing heteroaromatic rings. A sequence of aldol reaction between α-sulfonyl carbanion and aldehyde, trapping the resulting aldolate to give β-substituted sulfone, and double elimination of this intermediate can be integrated in one pot. This protocol allows thiophene, pyridine, and ferrocene units to be accommodated in phenylene ethynylene arrays.Key words: arylene–ethynylenes, heteroaromatic rings, ferrocene, double elimination, sulfones.
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Landmana, Marilé, Helmar Görls, Chantelle Crause, Hubert Nienaber, Andrew Olivier, and Simon Lotz. "Di-tungsten Bis-carbene Complexes Linked by Condensed Heteroaromatic Spacers." Zeitschrift für Naturforschung B 62, no. 3 (2007): 419–26. http://dx.doi.org/10.1515/znb-2007-0316.

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The 2,7-dilithiated substrates of 3,6-dimethylthieno[3,2-b]thiophene, N,N′-dimethylpyrrolo[3,2- b]pyrrole and N-methylthieno[3,2-b]pyrrole were reacted with W(CO)6 to give, after subsequent alkylation with Et3OBF4, the ditungsten biscarbene complexes [(CO)5W{C(OEt)XXC(OEt)} W(CO)5] (XX = condensed heteroaromatic spacers). Sites of attack during the dilithiation of the condensed rings were studied and compared, and the yields of the desired ditungsten biscarbene complexes optimized by changing the reaction conditions according to the role of the heteroatoms in the rings. The crystallographic da
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Mitsunuma, Harunobu, Hiromu Fuse, Yu Irie, et al. "(Invited) Identification of a Self-Photosensitizing Hydrogen Atom Transfer Organocatalyst System." ECS Meeting Abstracts MA2023-01, no. 14 (2023): 1355. http://dx.doi.org/10.1149/ma2023-01141355mtgabs.

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The carbon-hydrogen (C-H) bond is a fundamental chemical bond that constitutes organic molecules, and its direct conversion leads to highly efficient molecular synthesis. In recent years, the hydrogen atom transfer (HAT) catalysis using the energy of visible light, has been attracting attention. However, existing methods require the use of photoredox catalysts such as organic molecules with complex structures and expensive metal complexes. In this study, we developed an organocatalytic system that mimics the electron transfer process of enzymes in vivo and promotes functionalization of stable
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Meena, Chhuttan L., Shubdha Ingole, Satyendra Rajpoot, et al. "Discovery of a low affinity thyrotropin-releasing hormone (TRH)-like peptide that exhibits potent inhibition of scopolamine-induced memory impairment in mice." RSC Advances 5, no. 70 (2015): 56872–84. http://dx.doi.org/10.1039/c5ra06935a.

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Doerksen, Robert J., and Ajit J. Thakkar. "Quadrupole and Octopole Moments of Heteroaromatic Rings." Journal of Physical Chemistry A 103, no. 48 (1999): 10009–14. http://dx.doi.org/10.1021/jp992524v.

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Gamez, Patrick, Tiddo J. Mooibroek, Simon J. Teat та Jan Reedijk. "Anion Binding Involving π-Acidic Heteroaromatic Rings". Accounts of Chemical Research 40, № 6 (2007): 435–44. http://dx.doi.org/10.1021/ar7000099.

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Katritzky, Alan R., and Nicholas Dennis. "Cycloaddition reactions of heteroaromatic six-membered rings." Chemical Reviews 89, no. 4 (1989): 827–61. http://dx.doi.org/10.1021/cr00094a006.

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Thorimbert, Serge, Candice Botuha, and Kevin Passador. "‘Heteroaromatic Rings of the Future’: Exploration of Unconquered Chemical Space." Synthesis 51, no. 02 (2018): 384–98. http://dx.doi.org/10.1055/s-0037-1611279.

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William Pitt and co-workers have created a virtual exploratory heterocyclic library ‘VEHICLe’ containing over 200 unconquered bicyclic heteroaromatic rings, synthetically feasible with potential medicinal interest. Since the publication of the 22 ‘heteroaromatic rings of the future’ by Pitt in 2009, 15 of them have been successfully synthesized as bicyclic or polycyclic forms and evaluated for applications in both biology and material science. This short review presents the critical synthesis associated with innovative synthetic methodologies of the synthetically conquered ring scaffolds from
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Dissertations / Theses on the topic "Heteroaromatic rings"

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GRIECO, ILENIA. "Synthesis of ATP-competitive CK1δ inhibitors: exploring heteroaromatic systems as promising tools for neurodegenerative diseases". Doctoral thesis, Università degli Studi di Trieste, 2023. https://hdl.handle.net/11368/3041019.

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Casein Kinase 1 isoform δ (CK1δ) belongs to Protein Kinase (PK) superfamily and it is involved in several cellular processes and in neurodegenerative disorders including Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyotrophic Lateral Sclerosis (ALS). The PhD thesis is focused on the development of ATP-competitive CK1δ inhibitors by exploring heteroaromatic systems applying three main strategies: metabolic-based design, new scaffold development and molecular simplification approach. The first investigated scaffold involves the benzo[d]thiazole nucleus; Riluzole, approved drug for Amy
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Slater, Rachel. "Polyfunctional heteroaromatic fused ring systems." Thesis, Durham University, 2005. http://etheses.dur.ac.uk/2755/.

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Many current therapeutic agents are based on a core structure consisting of a fused ring heteroaromatic polycyclic system. Methodology for the synthesis of a range of these structurally diverse heteroaromatic derivatives is therefore highly desirable and short, high yielding, regioselective and flexible routes to such systems is very important. Our methodology utilises nucleophilic substitution reactions between pentafluoropyridine (PFP) and its derivatives, and various binucleophiles, e.g. The methodology has also been extended to 4-substituted tetrafluoropyridine derivativesand different bin
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Vosswinkel, Michael. "Ring expansion and ring opening of heteroaromatic nitrenes." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968868576.

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Mackay, C. "Spirocyclic intermediates in the electrophilic ring closures of heterocycles." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233067.

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Cavitt, Marchello Alfonzo. "Stress relief: Exercising Lewis acid catalysis for donor-acceptor cyclopropane ring-opening annulations, a basis for new reaction methodologies." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54448.

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Nature’s biodiversity is complex and filled with beauty and wonder which are all observable on the macroscopic scale. This exquisiteness of nature’s intricacies are mirrored on the molecular level such that substances, large or small, are assembled to serve as signaling molecules, protective agents, and fundamental composites of higher-order frameworks for the operation and survival of life. Over the years, chemists have isolated and synthesized these molecules, known as natural products, to understand and evaluate their functions in biology and potential for medicinal applications. Although
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Yang, Hua. "Synthesis of novel polycyclic aromatics and heteroaromatics via cascade cyclizations of enyne-allenes and enyne-isocyanates." Morgantown, W. Va. : [West Virginia University Libraries], 2006. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=4515.

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Thesis (Ph. D.)--West Virginia University, 2006.<br>Title from document title page. Document formatted into pages; contains xv, 110, [139] p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 102-110).
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Aponte-Guzman, Joel. "Ring-Opening Benzannulations of Cyclopropenes, Alkylidene Cyclopropanes, and 2,3-Dihydrofuran Acetals: A complementary Approach to Benzo-fused (Hetero)aromatics." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54916.

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Over the past decades, functional group manipulation of aromatic precursors has been a common strategy to access new aromatic compounds. However, these classical methods, such as Friedel-Crafts alkylations and electrophilic/nucleophilic aromatic substitutions, have shown lack of regioselectivity besides the use of activators in excess amounts. To this end, numerous benzannulations to form benzo-fused substrates via Diels-Alder (DA), ring-closing metathesis (RCM), cycloaddition, and transition-metal-promoted processes have been reported. Appending a benzene ring directly onto a pre-existing rin
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Voßwinkel, Michael [Verfasser]. "Ring expansion and ring opening of heteroaromatic nitrenes / vorgelegt von Michael Voßwinkel." 2003. http://d-nb.info/968868576/34.

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楊保華. "Physical properties and photorearrangements of heteroaromatic ring-fused benzobarrelenes." Thesis, 1992. http://ndltd.ncl.edu.tw/handle/52744477482769872625.

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Book chapters on the topic "Heteroaromatic rings"

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Yamamoto, Takakazu, Isao Yamaguchi, and Takuma Yasuda. "PAEs with Heteroaromatic Rings." In Poly(arylene etynylene)s. Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/b101378.

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Buisson, J. P., J. Y. Mevellec, S. Zeraoui, and S. Lefrant. "Vibrational Properties of Conducting Polymers with Aromatic or Heteroaromatic Rings." In Lower-Dimensional Systems and Molecular Electronics. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4899-2088-1_41.

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Dalvie, Deepak, Ping Kang, Cho-Ming Loi, Lance Goulet, and Sajiv Nair. "Chapter 7. Influence of Heteroaromatic Rings on ADME Properties of Drugs." In Drug Discovery. Royal Society of Chemistry, 2010. http://dx.doi.org/10.1039/9781849731102-00328.

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Colthup, Norman B., Lawrence H. Daly, and Stephen E. Wiberley. "AROMATIC AND HETEROAROMATIC RINGS." In Introduction to Infrared and Raman Spectroscopy. Elsevier, 1990. http://dx.doi.org/10.1016/b978-0-08-091740-5.50011-9.

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Ramsden, Christopher A. "Semi-Conjugated Heteroaromatic Rings." In Progress in Heterocyclic Chemistry. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-08-100755-6.00001-6.

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Lin-Vien, Daimay, Norman B. Colthup, William G. Fateley, and Jeanette G. Grasselli. "Aromatic and Heteroaromatic Rings." In The Handbook of Infrared and Raman Characteristic Frequencies of Organic Molecules. Elsevier, 1991. http://dx.doi.org/10.1016/b978-0-08-057116-4.50023-7.

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Chandrashekharappa, Sandeep, Subrata Barick, and Kaustav Dhara. "Biological Relevance of Five Membered Fused Heterocycle Imidazothiazole." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch001.

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Heterocyclic compounds are essential in the metabolism of all living cells, and most nitrogen-containing fused heterocyclic compounds with five-membered rings are biologically active. Nitrogen and sulphur-containing heteroaromatic compounds, such as imidazothiazoles and their derivatives, are acknowledged for their biological activity and substantial contributions to medicinal chemistry. Imidazothiazoles are defined by their fused bicyclic structure, merging an imidazole ring (a five-membered ring with two non-adjacent nitrogen atoms) with a thiazole ring (a five-membered ring containing both
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"Pd-Mediated Arylation of Aromatic and Heteroaromatic Rings." In Organic Synthesis: State of the 2005-2007. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470385975.ch13.

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"Biocatalytic Disconnections and Functional Group Interconversions." In Biocatalysis in Organic Synthesis: The Retrosynthesis Approach. The Royal Society of Chemistry, 2018. http://dx.doi.org/10.1039/bk9781782625308-00268.

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This chapter introduces the idea of developing a structured approach to the disconnection of target molecules based on biocatalytic retrosynthesis. The reader will be guided through the various disconnections that are possible, both for acyclic and cyclic systems, in order to gain an understanding of where biocatalysts can be applied in organic synthesis. The various disconnections possible are organised into one of five different groups: (i) acyclic systems: substituted alcohols, amines, carboxylic acids, ketones etc. (1 functional group); (ii) acyclic systems: 1,2-, 1,3-, and 1,4-diols, hydr
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"Best Synthetic Methods: Construction of Aromatic and Heteroaromatic Rings." In Organic Synthesis. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/0470056312.ch86.

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Conference papers on the topic "Heteroaromatic rings"

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Padmaperuma, Asanga B., and Aaron W. Harper. "Photophysics of novel conjugated polymers with alternating heteroaromatic rings: synthesis and applications." In Optical Science and Technology, SPIE's 48th Annual Meeting, edited by Zakya H. Kafafi and Paul A. Lane. SPIE, 2004. http://dx.doi.org/10.1117/12.505952.

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Júnior, Paulo Eliandro da Silva, A. Ganesan, James Dale, and Flavio Emery. "Synthesis and reactivity of pyrazolo-pyridone ring, an understudied heteroaromatic scaffold." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013915143915.

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Dekamin, Mohammadghorban, and Zahra Alirezvani. "A convenient synthesis of bis(indolyl)methane derivatives using heteroaromatic isocyanurate ring functionalized MCM-41 as a new and highly efficient reusable catalyst." In The 21st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04739.

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