Academic literature on the topic 'Heterocycles and applications'

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Journal articles on the topic "Heterocycles and applications"

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Andres, C. J., Derek J. Denhart, Milind S. Deshpande, and Kevin W. Gillman. "Recent Advances in the Solid Phase Synthesis of Drug Heterocyclic Small Molecules." Combinatorial Chemistry & High Throughput Screening 2, no. 4 (1999): 191–210. http://dx.doi.org/10.2174/1386207302666220204193145.

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Abstract: Because of their synthetic challenge, broad range of physical I chemical properties, and diverse biological activities, heterocycles continue to be of interest to both the academic and industrial chemist. This review covers recent advances in the solid phase synthesis of drug-like heterocyclic small molecules. Syntheses which form the heterocycle on the solid phase are emphasized; syntheses in which a preformed heterocycle is functionalized on the solid support have been omitted. The majority of references are from publication year 1999. This review should be of interest to anyone in
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Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo, and Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles." Current Organic Synthesis 15, no. 8 (2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.

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Background: 1,4-Dithiane-2,5-diol (1,4-DTD) is the stable dimer of α-mercapto acetaldehyde. This commercially available ambidentade compound is characterized as having in its chemical structure one group that acts as an electrophile and another that acts as a nucleophile, this permits its use as versatile and efficient synthon in synthetic heterocycle procedures. Objective: The aim of this review is to present synthetic applications of 1,4-DTD in heterocyclic chemistry and their applicability to the synthesis of bioactive compounds. Conclusion: Gewald reactions to obtain C-4 and C-5 unsubstitu
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Hoffman, Gavin R., and Allen M. Schoffstall. "Syntheses and Applications of 1,2,3-Triazole-Fused Pyrazines and Pyridazines." Molecules 27, no. 15 (2022): 4681. http://dx.doi.org/10.3390/molecules27154681.

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Pyrazines and pyridazines fused to 1,2,3-triazoles comprise a set of heterocycles obtained through a variety of synthetic routes. Two typical modes of constructing these heterocyclic ring systems are cyclizing a heterocyclic diamine with a nitrite or reacting hydrazine hydrate with dicarbonyl 1,2,3-triazoles. Several unique methods are known, particularly for the synthesis of 1,2,3-triazolo[1,5-a]pyrazines and their benzo-fused quinoxaline and quinoxalinone-containing analogs. Recent applications detail the use of these heterocycles in medicinal chemistry (c-Met inhibition or GABAA modulating
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Masdeu, Carme, Maria Fuertes, Endika Martin-Encinas, et al. "Fused 1,5-Naphthyridines: Synthetic Tools and Applications." Molecules 25, no. 15 (2020): 3508. http://dx.doi.org/10.3390/molecules25153508.

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Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in the fields of synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological activities. In this review, a wide range of synthetic protocols for the construction of this scaffold are presented. For example, Friedländer, Skraup, Semmlere-Wolff, and hetero-Diels-Alder, among others, are well known classical synthetic protocols used for the construction of the main 1,5-naphthyridine scaffold. These syntheses are classified
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Boelke, Andreas, Soleicha Sadat, Enno Lork, and Boris J. Nachtsheim. "Pseudocyclic bis-N-heterocycle-stabilized iodanes – synthesis, characterization and applications." Chemical Communications 57, no. 60 (2021): 7434–37. http://dx.doi.org/10.1039/d1cc03097c.

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Kerru, Nagaraju, Lalitha Gummidi, Suresh Maddila, Kranthi Kumar Gangu, and Sreekantha B. Jonnalagadda. "A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications." Molecules 25, no. 8 (2020): 1909. http://dx.doi.org/10.3390/molecules25081909.

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The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The number of novel N-heterocyclic moieties with significant physiological properties and promising applications in medicinal chemistry is ever-growing. In this review, we co
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Yadav, Shailendra, Sushma Singh, and Chitrasen Gupta. "A CONCISE OVERVIEW ON HETEROCYCLIC COMPOUNDS EXHIBITING PESTICIDAL ACTIVITIES." International Journal of Advanced Research 9, no. 08 (2021): 989–1004. http://dx.doi.org/10.21474/ijar01/13352.

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Heterocyclic compounds are numerous and diverse group of organic compounds. Heterocycles are abundantly found in nature and express various physiological properties. Heterocycles are intricately linked to all aspects of life. There are many heterocyclic compounds currently known, and the number is constantly rising owing to extensive synthetic development and their applications. Heterocyclic compounds are used significantly in a number of areas, including biochemistry and medicinal chemistry, and some others. They are predominantly synthesized in agrochemical and pharmaceutical industries due
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Niedballa, Jonas, and Thomas J. J. Müller. "Heterocycles by Consecutive Multicomponent Syntheses via Catalytically Generated Alkynoyl Intermediates." Catalysts 12, no. 1 (2022): 90. http://dx.doi.org/10.3390/catal12010090.

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Multicomponent processes are beneficial tools for the synthesis of heterocycles. As densely substituted bifunctional electrophiles, ynones are essential intermediates by applying cyclocondensations or cycloadditions in numerous heterocycle syntheses. The respective alkynoyl intermediates are generally accessible by palladium-, copper- and palladium/copper-catalyzed alkynylation. In turn, the mild reaction conditions allow for a fast and versatile entry to functional heterocycles in the sense of consecutive multicomponent processes. This review collates and presents recent advances in accessing
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Sparr, Christof, and Christian Fischer. "Configurationally Stable Atropisomeric Acridinium Fluorophores." Synlett 29, no. 16 (2018): 2176–80. http://dx.doi.org/10.1055/s-0037-1610233.

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Arylated heterocyclic fluorophores are particularly useful scaffolds for numerous applications, such as bioimaging or synthetic photochemistry. While variation of the substitution pattern at the heterocycle and aryl groups allows dye modulation, the bond rotational barriers are also strongly affected. Unsymmetrically substituted ring systems of rotationally restricted arylated heterocycles therefore lead to configurationally stable atropisomeric fluorophores. Herein, we describe these characteristics by determining the properties and configurational stability of atropisomeric, tri-ortho-substi
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Keszei, Soma J., Márk Váradi, and Rita Skoda-Földes. "Urea-Functionalized Heterocycles: Structure, Hydrogen Bonding and Applications." Molecules 28, no. 23 (2023): 7757. http://dx.doi.org/10.3390/molecules28237757.

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Ureido-heterocycles exhibiting different triple- and quadruple H-bonding patterns are useful building blocks in the construction of supramolecular polymers, self-healing materials, stimuli-responsive devices, catalysts and sensors. The heterocyclic group may provide hydrogen bond donor/acceptor sites to supplement those in the urea core, and they can also bind metals and can be modified by pH, redox reactions or irradiation. In the present review, the main structural features of these derivatives are discussed, including the effect of tautomerization and conformational isomerism on self-assemb
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Dissertations / Theses on the topic "Heterocycles and applications"

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Richmond, Craig J. "Applications for imidazophenanthridine-based heterocycles." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/1406/.

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The physical properties and reactivity of 2,3-dihydro-1H-imidazo[1,2-f]phenanthridinium cations (DIPs) and analogous heterocycles have been investigated. The adapted syntheses developed were applied to a range of aryl amines and more elaborate substrates, such as bifunctional aminoquinolinium cations and amino functionalised polyoxometalates (POMs). 1,2,3,12b-tetrahydroimidazo[1,2-f]phenanthridines (TIPs), an intermediate in the 3-step cascade synthesis of DIPs, have also been isolated. Derivatisation of the TIP structure at the imidazo-N position enables control of the reactivity of the inter
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Davies, Deiniol Hedd. "Synthesis and applications of Guanidine Heterocycles." Thesis, Bangor University, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.519556.

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Mossaraf, Hossain. "Solvent free synthesis of some heterocycles and their applications." Thesis, University of North Bengal, 2017. http://ir.nbu.ac.in/handle/123456789/2621.

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Rozgowska, Emma Jayne. "N-amino heterocycles : applications in flash vacuum pyrolysis." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5280.

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Routes to N-amino heterocycles were reviewed and findings applied to generate flash vacuum pyrolysis (FVP) precursors of two types - ketene generators and azol-1-yl radical generators. N-Amino heterocycles can be used as nitrogen radical generators, the N-N bond being homolytically cleaved at furnace temperatures of approximately 850 °C. A number of 2-substituted benzimidazoles were synthesised and subsequently Naminated. The 2-arylbenzimidazole precursors 1-amino-2-(2-methylphenyl)-1Hbenzimidazole and 1-amino-2-(2-ethylphenyl)-1H-benzimidazole were synthesised and subjected to FVP. The hydrog
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Tao, Beata 1973. "Applications of planar-chiral heterocycles in asymmetric catalysis." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/8047.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2002.<br>Vita.<br>Includes bibliographical references.<br>The development of planar-chiral heterocycles for asymmetric catalysis and their applications to enantioselective processes were investigated. Reactions including the kinetic resolution of propargylic alcohols, the enantioselective ring opening of meso epoxides, and the asymmetric hydrosilylation of ketones were studied. ... During the past few years, our group has developed lb as one of the most effective and versatile nonenzymatic acylation catalysts for the k
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Shrestha, Tej Bahadur. "Heterocycles for life-sciences applications and information storage." Diss., Kansas State University, 2010. http://hdl.handle.net/2097/13540.

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Doctor of Philosophy<br>Department of Chemistry<br>Stefan H. Bossmann<br>The photochromic spirodihydroindolizine/betaine (DHI/B) system has been reinvestigated applying picosecond, microsecond, stationary absorption measurements, and NMR-kinetics. The first surprise was that the electronic structure of the betaines is quite different than commonly assumed. The photochemical ring-opening of DHIs to betaines is a conrotatory 1,5 electrocyclic reaction, as picosecond absorption spectroscopy confirms. The (disrotatory) thermal ring-closing occurs from the cisoid betaine. The lifetime of the transo
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Goon, Simon. "Applications of the Vilsmeier reagent in synthesis." Thesis, University of Sunderland, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245363.

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Melling, Robert Craig. "Synthesis and applications of enantiopure N-heterocycles of C2-symmetry." Thesis, Queen Mary, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393104.

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Fra, Fernández Laura. "New Applications of Iodine(III) Reactivity: Synthesis and Functionalization of Heterocycles." Doctoral thesis, Universitat Rovira i Virgili, 2017. http://hdl.handle.net/10803/456301.

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S'han desenvolupat dues metodologies diferents per a la síntesi de indols emprant la reactivitat de iode hipervalente. En primer lloc, s'ha proposat una reacció de ciclació en la qual s'han obtingut un total de 21 exemples amb bons rendiments, a més d'estudiar el possible mecanisme d'aquesta reacció a través de diferents proves mecanístiques com ara la tècnica de marcatge de deuteri . D'altra banda, s'ha realitzat una metodologia alternativa amb substrats de partida diferents per obtenir un total de 18 exemples en bons rendiments a través tant d'una transformació estequiomètrica com catalítica
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Gentili, Denis <1982&gt. "Synthesis of five-membered heterocycles and of nanostructured systems for nanomedicine applications." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amsdottorato.unibo.it/2461/1/Gentili_Denis_tesi.pdf.

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Books on the topic "Heterocycles and applications"

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R, Katritzky Alan, ed. Novel applications of heterocycles in synthesis. Pergamon, 1996.

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R, Katritzky Alan, Soldatenkov, A. T. (Anatoliĭ Timofeevich), and ebrary Inc, eds. Heterocycles in life and society: An introduction to heterocyclic chemistry, biochemistry and applications. 2nd ed. Wiley, 2011.

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The chemistry of heterocycles: Structure, reactions, syntheses, and applications. 2nd ed. Wiley-VCH, 2003.

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Eicher, Theophil. The chemistry of heterocycles: Structure, reactions, syntheses, and applications. 2nd ed. Wiley-VCH, 2004.

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Eicher, Theophil. The chemistry of heterocycles: Structure, reactions, syntheses, and applications. G. Thieme, 1995.

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Synthetic applications of 1,3-dipolar cycloaddition chemistry toward heterocycles and natural products. Wiley, 2003.

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Padwa, Albert, and William H. Pearson, eds. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products. John Wiley & Sons, Inc., 2002. http://dx.doi.org/10.1002/0471221902.

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service), SpringerLink (Online, ed. Halogenated Heterocycles: Synthesis, Application and Environment. Springer Berlin Heidelberg, 2012.

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1956-, Nylund Kristian, and Johansson Peder 1945-, eds. Heterocyclic compounds: Synthesis, properties, and applications. Nova Science Publishers, 2009.

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Patel, Ramesh. Triazines: Synthesis, applications, and toxicity. Nova Science Publishers, 2011.

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Book chapters on the topic "Heterocycles and applications"

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Dwivedi, Sumant, and Tatsuo Kaneko. "Aromatic Bioplastics with Heterocycles." In Green Polymer Chemistry: New Products, Processes, and Applications. American Chemical Society, 2018. http://dx.doi.org/10.1021/bk-2018-1310.ch014.

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Mele, Giuseppe, Diego Lomonaco, and Selma E. Mazzetto. "Cardanol-Based Heterocycles: Synthesis and Applications." In Cashew Nut Shell Liquid. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47455-7_3.

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Nešpůrek, S., J. Sworakowski, J. Lipiński, S. Böhm, and J. Kuthan. "Photocolouration of Hypervalent Heterocycles." In Multiphoton and Light Driven Multielectron Processes in Organics: New Phenomena, Materials and Applications. Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-011-4056-0_20.

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Akritopoulou-Zanze, Irini, and Stevan W. Djuric. "Applications of MCR-Derived Heterocycles in Drug Discovery." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/7081_2010_46.

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Akritopoulou-Zanze, Irini. "Applications of Isocyanides in the Synthesis of Heterocycles." In Isocyanide Chemistry. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652532.ch13.

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Chaudhuri, Haribandhu, Bhaskar Sarmah, and Niranjan Karak. "Synthesis of Heterocycles Over Nanoporous Zeolites." In Handbook of Nanomaterials and Nanocomposites for Energy and Environmental Applications. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-11155-7_26-1.

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Dake, Satish A., Swapanil R. Sarda, Rajendra P. Marathe, et al. "Imidazolium Ionic Liquids: An Environment-Friendly Medium for Various Applications." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_7.

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Rostamnia, Sadegh, and Esmail Doustkhah. "Synthesis and Synthetic Applications of Biologically Interesting Rhodanine and Rhodanine-Based Scaffolds." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_9.

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Chung, Cheol K., and Matthew L. Crawley. "Transition Metal-Catalyzed Synthesis of Five- and Six-Membered Heterocycles." In Applications of Transition Metal Catalysis in Drug Discovery and Development. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118309872.ch6.

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Ukaji, Yutaka, and Takahiro Soeta. "Development of New Methods for The Construction of Heterocycles Based on Cycloaddition Reaction of 1,3-Dipoles." In Methods and Applications of Cycloaddition Reactions in Organic Syntheses. John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781118778173.ch11.

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Conference papers on the topic "Heterocycles and applications"

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Prima, D. O., D. S. Baev, E. V. Vorontsova, et al. "New cancer cells apoptosis agents: Fluorinated aza-heterocycles." In PHYSICS OF CANCER: INTERDISCIPLINARY PROBLEMS AND CLINICAL APPLICATIONS: Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17). Author(s), 2017. http://dx.doi.org/10.1063/1.5001636.

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Castro, M. Cidália R., A. Maurício C. Fonseca, M. Belsley, and M. Manuela M. Raposo. "Highly efficient and thermally stable NLO organic materials based on pyrrole and thiophene heterocycles." In International Conference on Applications of Optics and Photonics, edited by Manuel F. Costa. SPIE, 2011. http://dx.doi.org/10.1117/12.892205.

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Castro, M. Cidália R., A. Maurício C. Fonseca, M. Belsley та M. Manuela M. Raposo. "Synthesis and evaluation of NLO properties of π-conjugated donor-acceptor systems bearing pyrrole and thiophene heterocycles". У International Conference on Applications of Optics and Photonics, редактор Manuel F. Costa. SPIE, 2011. http://dx.doi.org/10.1117/12.892124.

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Fadil MOUSA, Enaam, and Ibtissam Khalifa JASSIM. "SYNTHESIS ,CHARACTERIZATION AND BIOLOGICAL ACTIVITY STUDY OF SOME HETEROCYCLIC COMPOUNDS." In IV.International Scientific Congress of Pure,Appliedand Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress4-18.

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Heterocycles are an important class of organic compounds because of their applications in medicines and industrial fields. Therefore our study included preparation of these compound such as oxazepine and quinazoline rings, which were prepared through two steps: The first step included the reaction of the Schiff bases derived from sulfamethaxazole (1-4) with each of phthalic anhydride and 3- nitrophthalic anhydride for the preparation of oxazepines (5-12) .While the second step included the preparation of quinazoline compounds (13-16) from the reaction of Schiff bases (1-4) with anthranilic aci
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Stevanović, Nevena Lj, Mia Stanković, Tina P. Andrejević, Darko P. Ašanin, Ivana M. Stanojević, and Biljana Đ. Glišić. "DNA AND BSA INTERACTIONS OF COPPER(II) AND ZINC(II) COMPLEXES WITH ANTIFUNGAL AGENT FLUCONAZOLE." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.399s.

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Aromatic nitrogen-containing heterocycles (N-heterocycles) have attracted a considerable attention as scaffolds for compounds, which have an application in different pharmacological areas, ranging from vitamins to different antimicrobial and antitumor agents. In this respect, azoles are of special importance as potent and broad-spectrum agents used for the treatment of many invasive fungal infections. In the present study, the interaction of the clinically used antifungal drug fluconazole (fcz) and its copper(II) and zinc(II) complexes, {[CuCl2(fcz)2].5H2O}n (1) and {[ZnCl2(fcz)2]·2C2H5OH}n (2
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Rosa, Fernanda A., Michael J. V. da Silva, Davana S. Gonçalves, Daniela H. Arita, Camila S. S. Tozatti, and Gisele de F. G. Bandoch. "Synthetic Application of New Enaminodiketone: Regioespecific Synthesis of Aza-Heterocycles." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013101145054.

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Ariunbold, Gombojav O., Bryan Semon, Surpiya Nagpal, and Yuri Rostovtsev. "Cooperative Emissions from Hydrogen-Bonded Heterocyclic Organic Compounds." In CLEO: Applications and Technology. OSA, 2020. http://dx.doi.org/10.1364/cleo_at.2020.aw4k.4.

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Shutalev, Anatoly. "New Synthetic Application of Ureidoalkylation in Heterocyclic Chemistry." In The 1st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 1997. http://dx.doi.org/10.3390/ecsoc-1-02013.

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Twieg, Robert, S. Gu, L. Sukhomlinova, G. G. Malliaras, R. Fan, and D. Culjikovic. "Heterocyclic liquid crystals designed for optical light emitting diode applications." In Organic Thin Films. OSA, 1999. http://dx.doi.org/10.1364/otf.1999.sud1.

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Jaiswal, Shalini, Preeti Singh Bahadur, Ankita Mathur, and Ruchira Srivastava. "Nuclear Magnetic Resonance Spectroscopy Application in charterization of Heterocyclic Compounds." In 2021 International Conference on Technological Advancements and Innovations (ICTAI). IEEE, 2021. http://dx.doi.org/10.1109/ictai53825.2021.9673200.

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