Relevant bibliographies by topics / Heterocyclic and condensation

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Heterocyclic and condensation'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Heterocyclic and condensation.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Heterocyclic and condensation"

1

Su, Biyun, Yifan Hou, Li Wang та ін. "The Syntheses, Characterization and Crystal Structures of a Series of Heterocyclic β-Diketones and Their Isoxazole Compounds". Current Organic Synthesis 16, № 8 (2020): 1174–84. http://dx.doi.org/10.2174/1570179416666191022113022.

Full text
Abstract:
Background: In the field of coordination chemistry, the introduction of heterocyclic substituents into the structure of β-diketone enables ligand to produce multiple coordination sites. The adoption of small steric oxime group into the structure of heterocyclic β-diketone by Schiff-base condensation will further increase coordination sites and facilitate the generation of polynuclear structures. Objective: A series of β-diketones (2a-2c) containing different heterocycles such as pyridine, thiophene and furan and their corresponding isoxazole compounds (3a-3c) were synthesized. Materials and Me
APA, Harvard, Vancouver, ISO, and other styles
2

Idrees Ibrahim, Hala. "Synthesis of some new heterocyclic compounds by High- Speed,Microwaveirradiation and pharmacological evaluation." Tikrit Journal of Pharmaceutical Sciences 9, no. 2 (2023): 338–55. http://dx.doi.org/10.25130/tjphs.2013.9.2.17.338.355.

Full text
Abstract:
A series of substituted chalcones (1-4) were synthesized and used to prepare some new membered heterocyclic compounds (Pyrimidinones)(5-12) by their condensation with urea and thiourea, and four membered heterocyclic compounds (Pyrazolines) (13-16) by their condensation with 2,4-dinitrophenyl hydrazine also, four membered heterocyclic compounds (isoxazolines) (17-20) by their condensation with aminohydroxide hydrochloride. All reactions were carried out under microwave irradiation (MW1) is described. The synthesized compounds are characterized by FTIR and C.H.N analysis. We also study the biol
APA, Harvard, Vancouver, ISO, and other styles
3

Shoji, Taku, Tetsuo Okujima, and Shunji Ito. "Development of Heterocycle-Substituted and Fused Azulenes in the Last Decade (2010–2020)." International Journal of Molecular Sciences 21, no. 19 (2020): 7087. http://dx.doi.org/10.3390/ijms21197087.

Full text
Abstract:
Azulene derivatives with heterocyclic moieties in the molecule have been synthesized for applications in materials science by taking advantage of their unique properties. These derivatives have been prepared by various methods, involving electrophilic substitution, condensation, cyclization, and transition metal-catalyzed cross-coupling reactions. Herein, we present the development of the synthetic methods, reactivities, and physical properties for the heterocycle-substituted and heterocycle-fused azulenes reported in the last decade.
APA, Harvard, Vancouver, ISO, and other styles
4

Borré, Etienne, Georges Dahm, Gilles Guichard, and Stéphane Bellemin-Laponnaz. "Post-functionalization of platinum–NHC complexes by oxime ligation for ligand targeted therapy." New Journal of Chemistry 40, no. 4 (2016): 3164–71. http://dx.doi.org/10.1039/c5nj03104d.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Fernandes, Sara S. M., Maria Cidália R. Castro, Dzmitry Ivanou, Adélio Mendes, and Maria Manuela M. Raposo. "Push-Pull Heterocyclic Dyes Based on Pyrrole and Thiophene: Synthesis and Evaluation of Their Optical, Redox and Photovoltaic Properties." Coatings 12, no. 1 (2021): 34. http://dx.doi.org/10.3390/coatings12010034.

Full text
Abstract:
Three heterocyclic dyes were synthesized having in mind the changes in the photovoltaic, optical and redox properties by functionalization of 5-aryl-thieno[3,2-b]thiophene, 5-arylthiophene and bis-methylpyrrolylthiophene π-bridges with different donor, acceptor/anchoring groups. Knoevenagel condensation of the aldehyde precursors with 2-cyanoacetic acid was used to prepare the donor-acceptor functionalized heterocyclic molecules. These organic metal-free dyes are constituted by thieno[3,2-b]thiophene, arylthiophene, bis-methylpyrrolylthiophene, spacers and one or two cyanoacetic acid acceptor
APA, Harvard, Vancouver, ISO, and other styles
6

Bassam A. Hassan, Hameedi N Nasera, and Maitham M. Abdulridha. "Synthesis and antimicrobial evaluation of fused heterocyclic compound [1,2,4] triazolo [4,3-b][1,2,4,5] tetra zine." International Journal of Research in Pharmaceutical Sciences 10, no. 2 (2019): 1254–58. http://dx.doi.org/10.26452/ijrps.v10i2.417.

Full text
Abstract:
Nitrogen-containing, heterocycles, have special importance and vital, role in the discovery of effective bioactive, agents in the pharmaceutical, industry. The present article reports the synthesis of new fused, heterocycles triazolotetrazine by cyclo condensation, reaction as shown in scheme(1). The structures formula of synthesized compounds newly was evaluated by Ft-IR,1H-NMR spectrum, and C, H, N elemental analysis. Antimicrobial activity of triazolotetrazine studied against some pathogenic bacterial strains isolated from patients like Acinetobacter, Aeromonas, E. coli, Klebsiella, Staphyl
APA, Harvard, Vancouver, ISO, and other styles
7

Kato, Terumasa, Shin-ichi Matsuoka, and Masato Suzuki. "N-Heterocyclic carbene-mediated redox condensation of alcohols." Chemical Communications 52, no. 55 (2016): 8569–72. http://dx.doi.org/10.1039/c6cc04154j.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Halah Hameed Majeed and Abbas F. Abbas. "Synthesis ,Characterization and Antioxidant Activity of Schiff base derivatives from [6,6'-(1,4-phenylene)bis(4-(4-aminophenyl) pyrimidin)]." Journal of Kufa for Chemical Sciences 3, no. 1 (2023): 313–44. http://dx.doi.org/10.36329/jkcm/2023/v3.i1.12098.

Full text
Abstract:
Two Hetreterocyclic compounds prepared from condensation reaction of Bis chalcone([3,3(1,4-phenylene)bis(1(4-aminophenyl)prop-2-en-1-one]with thiourea and urea By condensing a novel six-member heterocyclic (pyrimidene ring) with the suitable aromatic, new substituted azomethines of (o, m, and p) hydroxybenzaldehyde with heterocyclic substituents were created. By using NMR and FTIR spectroscopy, the novel heterocyclic compounds and these derivatives of schiff bases were identified.A DPPH free radical scavenging assay was performed on the synthesized compounds, and the heterocyclic substituted t
APA, Harvard, Vancouver, ISO, and other styles
9

Garmendia, Sofiem, Andrew P. Dove, Daniel Taton, and Rachel K. O'Reilly. "Self-catalysed folding of single chain nanoparticles (SCNPs) by NHC-mediated intramolecular benzoin condensation." Polymer Chemistry 10, no. 18 (2019): 2282–89. http://dx.doi.org/10.1039/c9py00149b.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Gianotti, Enrica, Ivana Miletto, Chiara Ivaldi, et al. "Hybrid catalysts based on N-heterocyclic carbene anchored on hierarchical zeolites." RSC Advances 9, no. 61 (2019): 35336–44. http://dx.doi.org/10.1039/c9ra07516j.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Heterocyclic and condensation"

1

Wu, Guanmin. "Synthesis and Characterization of 2,3-Dichloropyrrolo[1,2-a]benzimidazol-1-one and Its Methylthiol Derivatives." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5238/.

Full text
Abstract:
Condensation of 2,3-dichloromaleic anhydride and o-phenylenediamine in refluxing toluene affords the three compounds 2,3-dichloro-N-o-C6H4(NH2)maleimide (1), N,N¢-o-C6H4-bis(2,3-dichloromaleimide) (2), and 2,3-dichloropyrrolo[1,2-a]benzimidazol-1-one (3), with compound 1 as the major product. Repeating the same reaction in the presence of added PTSA furnishes compound 3 as the major product. Treatment of 3 with methylthiol in the presence of pyridine affords monosulfide compounds 2-chloro-3-methylthiopyrrolo[1,2-a]benzimidazol-1-one (4) and and the disulfide derivatives 2,3-di(methylthio)pyrro
APA, Harvard, Vancouver, ISO, and other styles
2

Pokharel, Uttam Raj. "ORGANOMETALLIC HETEROCYCLES AND ACENE-QUINONE COMPLEXES OF RUTHENIUM, IRON AND MANGANESE." UKnowledge, 2012. http://uknowledge.uky.edu/chemistry_etds/6.

Full text
Abstract:
A variety of organometallic-fused heterocycles and acene quinones were prepared and characterized. This work was divided into three parts: first, the synthesis of 5,5-fused heterocyclic complexes of tricarbonylmanganese and (1’,2’,3’,4’,5’-pentamethylcyclopentadienyl)ruthenium; second, the synthesis of 1,2-diacylcyclopentadienyl p-cymene complexes of ruthenium(II); and third, synthesis of cyclopentadienyl-fused polyacenequinone complexes of ruthenium, iron and manganese. The first examples of the convenient, versatile and symmetric cyclopentadienyl-fused heterocycle complexes of (1’,2’,3’,4’,5
APA, Harvard, Vancouver, ISO, and other styles
3

Corruble, Aline. "Amidures de lithium dérivés de 3-aminopyrrolidines : de nouveaux inducteurs chiraux pour l'alkylation d'aldéhydes par des organolithiens." Rouen, 1997. http://www.theses.fr/1997ROUES007.

Full text
Abstract:
Les amidures de lithium de 3-aminopyrrolidines chirales, synthétisées avec une pureté énantiomérique élevée (>90 %) à partir de la 1-benzyl-3(S)-aminopyrrolidine ou de la 4-hydroxy-(l)-proline, ont été testés comme nouveaux ligands chiraux dans la condensation énantiosélective d'organolithiens sur des aldéhydes aromatiques. L'étude de cette réaction a montré l'importance de l'encombrement du substituant de l'azote en position 3. Ainsi l'excès énantiomérique de l'alcool dérivé de l'ortho-tolualdéhyde et du n-butyllithium passe de 49% avec l'amidure de la 1-benzyl-3-(S)-benzylaminopyrrolidine à
APA, Harvard, Vancouver, ISO, and other styles
4

Nguyen, Thi Thao. "Synthèse et étude de dérivés porteurs du motif 1,3-dithiole-2-ylidene actifs en optique non linéaire de deuxième et troisième ordre." Angers, 1996. http://www.theses.fr/1996ANGE0003.

Full text
Abstract:
Ce travail porte sur la synthèse et l'étude de molécules potentiellement actives en optique non linéaire (ONL). Les chromophores pour l'ONL de 2ème ordre possèdent un groupement donneur d et un groupement accepteur a séparés par un espaceur conjugué e (d-e-a), d étant ici un groupement 1,3-dithiole-2-ylidene diversement substitué en position 4,5. Dans le but d'améliorer les performances non linéaires de ces molécules, on fait varier: i) le nombre de doubles liaisons conjuguées de l'espaceur e, ii) la nature de l'accepteur a (groupes carbonyle, carboxyalkyle, gem dicyano, p-nitrophenyle, 5-nitr
APA, Harvard, Vancouver, ISO, and other styles
5

Veyrat, Marc. "Synthèse de porphyrines et métalloporphyrines chirales dérivées d'aldéhydes alicycliques : application à la catalyse d'époxydation asymétrique d'alcènes." Université Joseph Fourier (Grenoble ; 1971-2015), 1994. http://www.theses.fr/1994GRE10191.

Full text
Abstract:
De nombreux prototypes de porphyrines comportant des superstructures chirales elaborees ont ete synthetises au cours de la derniere decennie, en vue de l'utilisation de leurs complexes metalliques comme catalyseurs d'epoxydation asymetrique des alcenes. L'utilite de ces composes est en general limitee, du fait de leur synthese laborieuse et des etapes de separation d'isomeres qu'elle comporte. L'approche originale decrite dans cette these fournit des catalyseurs asymetriques de structure plus simple, d'obtention plus facile, et donc potentiellement plus utiles. Une etude preliminaire, centree
APA, Harvard, Vancouver, ISO, and other styles
6

Elgadi, Abdelaziz. "Nouvelles applications de la réaction de darzens en synthèse." Nancy 1, 1987. http://www.theses.fr/1987NAN10028.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Jacoby, Denis. "Synthese et reactivite des cyclopropanes actives." Paris 6, 1987. http://www.theses.fr/1987PA066439.

Full text
Abstract:
Ce travail decrit des mises au point originales de preparations de pyrrolines et de dihydrofurannes a partir de cyclopropylcetoesters. Ces derniers sont prepares a partir de sels de triphenylphosphonium, precurseurs de derives cyclopropaniques. La reactivite de ces composes cyclopropaniques vis a vis de nucleophiles varies est etudiee. L'action des amines primaires permet d'obtenir des pyrrolines. Une etude biologique montre l'activite biocide des composes prepares
APA, Harvard, Vancouver, ISO, and other styles
8

Hamelin, Olivier. "Synthèses du (+)- et du (-)-9-acétoxyfukinanolide : Synthèse du (+)-dihydrofukinolidol, intermédiaire central des bakkénolides difonctionnalisés." Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10155.

Full text
Abstract:
Depuis bien une dizaine d'annees, une des activites de notre laboratoire est le developpement de nouvelles methodologies de synthese en vue d'acceder efficacement a une famille de composes particuliers que sont les bakkanes. Ils sont caracterises par la presence d'un squelette hydrindanique et d'une spiro, methylene, butyrolactone qui est a l'origine des activites biologiques tres diverses des bakkanes. Notre laboratoire avait developpe une approche souple et efficace des spirolactones hydrindaniques. Elle avait permis la synthese du ()- et du (+)-bakkenolide-a, du ()-homogynolide-b, du ()- et
APA, Harvard, Vancouver, ISO, and other styles
9

Dumas, Françoise. "Approches stéréoselectives d'antibiotiques de type carbapénème, thiénamycine et dérivés : contrôle relatif des centres asymétriques, construction du squelette bicyclique." Paris 6, 1987. http://www.theses.fr/1987PA066686.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

PETIT, YVES. "Synthese d'hydroxy-2 esters enantiomeriquement purs a partir d'amino-2 acide : etude stereochimique de l'addition 1,4 d'organometalliques sur des systemes insatures-2,3 hydroxy-4." Paris 6, 1987. http://www.theses.fr/1987PA066578.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Heterocyclic and condensation"

1

Davies, David T. "Introduction." In Aromatic Heterocyclic Chemistry. Oxford University Press, 1992. http://dx.doi.org/10.1093/hesc/9780198556602.003.0001.

Full text
Abstract:
This introductory chapter provides an overview of heterocyclic chemistry, which is a large and important branch of organic chemistry. Heterocycles occur in nature, for instance in nucleic acids and indole alkaloids. Synthetic heterocycles have widespread uses as herbicides, fungicides, insecticides, dyes, organic conductors, and, of course, pharmaceutical products such as the anti-ulcer drug. Any ring system containing at least one heteroatom can be described as heterocyclic. This broad definition encompasses both aromatic heterocycles and their non-aromatic counterparts. Aromatic heterocycles
APA, Harvard, Vancouver, ISO, and other styles
2

Singh, Rashmi, Rashmi Prakash, and Wim Dehaen. "Polycyclic heterocycles by condensation of 1,4-benzoquinone analogs and nucleophiles." In Advances in Heterocyclic Chemistry. Elsevier, 2021. http://dx.doi.org/10.1016/bs.aihch.2021.01.002.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Sasane, Nitin A., Hemantkumar N. Akolkar, Nirmala R. Darekar, Vijay M. Khedkar, Anand S. Burange, and Kulbhushan A. Sasane. "Isothiazoles: Synthetic Strategies and Pharmacological Applications." In S-Heterocycles. Royal Society of Chemistry, 2024. http://dx.doi.org/10.1039/9781837674015-00057.

Full text
Abstract:
Isothiazoles and their derivatives are a well-known class of heterocycles with five members containing sulfur atoms and have been widely used in the domains of organic chemistry, medicinal chemistry, and pharmaceuticals. The electronegativity of the heteroatoms (nitrogen and sulfur) and their 1,2-relationships make isothiazoles a significant class of compounds. Among numerous 1,2-azoles, isothiazoles have historically been recognized as an important class of compounds in various fields. Significant progress has been accomplished over the last ten years in the synthesis and functionalization of
APA, Harvard, Vancouver, ISO, and other styles
4

Sahu, Rojalin, and Puspanjali Sahu. "Synthesis of Metal Complexes from N-Heterocyclic Carbene and Schiff Base Ligands." In Metal Complexes: Environmental and Biomedical Applications. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815238723124010003.

Full text
Abstract:
The synthesis of transition metal complexes from N-heterocyclic carbene and Schiff base ligands is discussed in this chapter. A few basic characteristics of water-soluble, N-heterocyclic carbene-based complexes are also described. The increased hydrophilicity of these water-soluble metal complex-based catalysts improves their applicability. Though research based on carbon-carbon coupling reactions is dominating, recent studies demonstrate that water-soluble N-heterocyclic carbene-based complexes can be utilized in the hydrocyanation and metathesis reactions. Compounds formed by the condensatio
APA, Harvard, Vancouver, ISO, and other styles
5

Singh, Kawaljit, and Kamaljit Singh. "Biginelli Condensation: Synthesis and Structure Diversification of 3,4-Dihydropyrimidin-2(1H)-one Derivatives." In Advances in Heterocyclic Chemistry. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-396530-1.00003-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Nakamura, Seikou, Ikuo Kawasaki, Masami Terano, Masayuki Yamashita, and Shunsaku Ohta. "Regioselective Condensation of 1-Methyl-3-trimethylsilylimidazolidinetrione with Primary Amines." In 19th International Congress on Heterocyclic Chemistry. Elsevier, 2003. http://dx.doi.org/10.1016/b978-0-08-044304-1.50194-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Sanghavi, Kartik, Bonny Y. Patel, Vijay Khedkar, and Khushal M. Kapadiya. "Imidazo-Pyridines." In Advances in Chemical and Materials Engineering. IGI Global, 2025. https://doi.org/10.4018/979-8-3693-7267-8.ch011.

Full text
Abstract:
The structural resemblance between the fused imidazopyridine heterocyclic ring system (a purine system) has prompted biological investigations to assess their potential therapeutic significance. They are known to play a crucial role in numerous disease conditions. In recent years, new preparative methods for the synthesis of imidazopyridines using various catalysts or non-catalytic systems have been described. In the present chapter, we summarise the recent approaches adopted for the synthesis of functionalized imidazo-pyridines over the last two decades along with their clinical advancement a
APA, Harvard, Vancouver, ISO, and other styles
8

Nielsen, Flemming E., Søren Ebdrup, Hanne T. Kornø, Claus U. Jessen, Per O. G. Arkhammar, and John Bondo Hansen. "SYNTHESIS OF THIENO-1,2,4-THIADIAZINE 1,1-DIOXIDES VIA INTRAMOLECULAR COPPER PROMOTED CONDENSATION OF o-HALOTHIENYLSULFONYL GUANIDINES, AMIDINES OR ISOTHIOUREAS." In 19th International Congress on Heterocyclic Chemistry. Elsevier, 2003. http://dx.doi.org/10.1016/b978-0-08-044304-1.50253-7.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Singh, Sundaram, and Savita Kumari. "Use of Barbituric Acid as a Precursor for the Synthesis of Bioactive Compound." In Advances in Organic Synthesis. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815040791123180005.

Full text
Abstract:
Barbituric acid is an organic compound containing a pyrimidine heterocyclic skeleton. It is a water-soluble and odorless compound. Barbituric acid served as a starting material for many barbiturate drugs. The variable properties of the products achieved from barbituric acid motivate organic chemists to investigate its chemistry and current developments have suggested it by multicomponent reactions (MCR). Barbituric acid and its derivatives, commonly known as barbiturates, are important in pharmaceutical chemistry because they are fascinating building blocks for synthesizing biologically active
APA, Harvard, Vancouver, ISO, and other styles
10

Taber, Douglass. "Organocatalytic C-C Ring Construction: (+)-Ricciocarpin A (List) and (-)-Aromadendranediol (MacMillan)." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0073.

Full text
Abstract:
Yoshiji Takemoto of Kyoto University designed (Organic Lett. 2009, 11, 2425) an organocatalyst for the enantioselective conjugate addition of alkene boronic acids to γ-hydroxy enones, leading to 1 in high ee. Attempted Mitsunobu coupling led to the cyclopropane 2, while bromoetherification followed by intramolecular alkylation delivered the cyclopropane 3. Jeffrey W. Bode of the University of Pennsylvania demonstrated (Organic Lett. 2009, 11, 677) a remarkable dichotomy in the reactivity of N-heterocyclic carbenes. A triazolium precatalyst combined 4 and 5 to give 6, whereas an imidazolium pre
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Heterocyclic and condensation"

1

Pyrko, A. N. "ENVIRONMENTALLY FRIENDLY SYNTHESIS AND BIOLOGICAL TESTING FOR PESTICIDAL ACTIVITY OF HETEROCYCLIC ANALOGS OF STEROIDS." In SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2022. http://dx.doi.org/10.46646/sakh-2022-1-187-190.

Full text
Abstract:
The aim of the study is the synthesis and testing for pesticidal activities of 2,3-dimethoxy-16,16-dimethyl-D-homo-8-azagona-1,3,5 (10),13-tetraene-12,17а-one and 2,3-dimethoxy-16,16-dimethyl-d-homo-8-azagona-1,3,5(10),13-tetraene-12-imino-17а-one hydrochloride which could become the basis of plant protection products. The first compound was obtained by condensation of 6,7-dimethoxy-2,3-dihydroisoquinoline with 2-acetyl-5.5-dimethylcyclohexane-1,3-dione. The second substance was synthesized by interaction of the first with ammonium chloride. The synthesized compounds were tested for certain ty
APA, Harvard, Vancouver, ISO, and other styles
2

Bigović, Miljan, Marija Kaluđerović, Jovana Jovanović, Haris Majstorović, and Milica Kosović-Perutović. "Synthesis of Schiff bases between some five-membered heterocyclic aldehydes and thiocarbohydrazide (TCH) and optimization of reaction conditions." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.435b.

Full text
Abstract:
The usual way of synthesizing imines (Schiff bases) between carbonyl compounds –aldehydes and ketones – with thiocarbohydrazide (TCH) involves heating them for 3 hours in a mixture of water solvents and ethanol with the addition of a catalytic amount of concentrated hydrochloric acid. Heating in the presence of acid catalysts over a long period of time may be unsuitable for acid-sensitive, labile, reactive or thermally unstable aldehydes, which are prone to polymerization under these conditions. We tested the condensation reaction at room temperature with a series of aldehydes, while maintaini
APA, Harvard, Vancouver, ISO, and other styles
3

Verdes, Anastasia, Elena Gorincioi, Lucian Lupascu, Gheorghe Duca, and Fliur Macaev. "Targeting the bioactive dihydropyrimidines by ecofriendly procedure of biginelli reaction: study case of monastrol." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab24.

Full text
Abstract:
Biologically active compounds decorated with dihydropyridine moiety are counted amongst the numerous broad-spectrum therapeutic agents that explain the increasing role of this scaffold in rational drug design [1]. The Biginelli reaction is a multicomponent reaction of aldehyde, (thio)urea, and ß-ketoester, involving Mannich reaction in the first step, which produces multifunctionalized 3,4-dihydropyrimidin-2-(1H)-ones and related heterocyclic compounds [2]. The attractiveness of this acid-catalyzed one-pot condensation reaction lies in the simplicity of grafting the substituent into the struct
APA, Harvard, Vancouver, ISO, and other styles
4

Hussein, Ola, Feras Alali, Ala-Eddin Al Moustafa, and Ashraf Khalil. "Design, Synthesis and Biological Evaluation of Novel Chalcone Analogs as Potential Therapeutic Agents for Castration-Resistant Prostate Cancer." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0179.

Full text
Abstract:
Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of patients ultimately progress to a lethal form of the disease, termed as castration-resistant prostate cancer (CRPC), which currently lacks curative therapeutic options and is associated with poor prognosis. Therefore, the development of novel treatment modalities for PCa is urgently needed. Chalcones, also known as 1,3-diphenyl-2-propen-1-ones, are among the highly attractive
APA, Harvard, Vancouver, ISO, and other styles
5

Ungur, Nicon, Aurelian Gulea, and Tatiana Erhan. "Synthesis and study of the same hydrazincarbothioamides as privilege pharmacophores in pharmacology." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab05.

Full text
Abstract:
Hydrazinecarbothioamides represent a privileged class of pharmacophores in pharmacology, thanks to an impressive number of derivatives that exhibit outstanding antimicrobial, anticancer and antifungal properties [1]. The presence of electron donor atoms such as N(nitrogen) and S(sulfur) substantially widen the spectrum of use. In the framework of theoretical studies on the structure of biologically active compounds with valuable properties were highlighted following common structural elements such as substitution of a hydrogen atom from the nitrogen atom (N) with the benzene ring, the introduc
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Heterocyclic and condensation' for particular source types:
Journal articles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography