Academic literature on the topic 'Heterocyclic compoundis'

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Journal articles on the topic "Heterocyclic compoundis"

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Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo, and Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles." Current Organic Synthesis 15, no. 8 (2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.

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Background: 1,4-Dithiane-2,5-diol (1,4-DTD) is the stable dimer of α-mercapto acetaldehyde. This commercially available ambidentade compound is characterized as having in its chemical structure one group that acts as an electrophile and another that acts as a nucleophile, this permits its use as versatile and efficient synthon in synthetic heterocycle procedures. Objective: The aim of this review is to present synthetic applications of 1,4-DTD in heterocyclic chemistry and their applicability to the synthesis of bioactive compounds. Conclusion: Gewald reactions to obtain C-4 and C-5 unsubstitu
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Yadav, Shailendra, Sushma Singh, and Chitrasen Gupta. "A CONCISE OVERVIEW ON HETEROCYCLIC COMPOUNDS EXHIBITING PESTICIDAL ACTIVITIES." International Journal of Advanced Research 9, no. 08 (2021): 989–1004. http://dx.doi.org/10.21474/ijar01/13352.

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Heterocyclic compounds are numerous and diverse group of organic compounds. Heterocycles are abundantly found in nature and express various physiological properties. Heterocycles are intricately linked to all aspects of life. There are many heterocyclic compounds currently known, and the number is constantly rising owing to extensive synthetic development and their applications. Heterocyclic compounds are used significantly in a number of areas, including biochemistry and medicinal chemistry, and some others. They are predominantly synthesized in agrochemical and pharmaceutical industries due
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Palaniappan, Saravana Priya. "Pharmacological Role of Heterocyclic Compounds in the Treatment of Alzheimer’s Disease: A Review." Journal of Phytopharmacology 11, no. 4 (2022): 289–94. http://dx.doi.org/10.31254/phyto.2022.11412.

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Alzheimer’s disease (AD) is a multifactorial neurological disease that mainly affects the old age people. Neuropathologically, AD is characterized by low level of acetylcholine, loss of synapses and neurons in certain brain regions, accumulation of extracellular amyloid beta peptide (Aβ) and phosphorylation of intracellular tau protein. Patients with AD are characterized by various symptoms such as memory deficits, depression, cognitive dysfunction and difficult to perform daily activities. Currently available drugs for the treatment of AD are used to treat symptomatic relief at an early stage
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Olšovská, Jana, Karel Štěrba, Martin Slabý, and Tomáš Vrzal. "Novel method for determination of heterocyclic compounds and their impact in brewing technology." KVASNY PRUMYSL 67, no. 2 (2021): 417–27. http://dx.doi.org/10.18832/kp2021.67.417.

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A new simultaneous method for determination of 16 heterocyclic compounds using SPE sample preparation and GC-MS determination was developed regarding increasing interest of the role of sensory active compounds in beer. LiChrolut® EN SPE columns proved to be optimal for both, a mixture of analytes with a different polarity and such complicated matrix as beer. Recoveries of individual analytes are about 100% except for three compounds (2-methylpyridine about 30%, maltol and furaneol about 50%); repeatability, uncertainty and LOQ are satisfactory for the method application. The method was used fo
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Bhattacharya, Somenath, Soumallya Chakraborty, Rohan Pal, et al. "A Comprehensive Review on Pyrazole and It’s Pharmacological Properties." International Journal for Research in Applied Science and Engineering Technology 10, no. 9 (2022): 1769–74. http://dx.doi.org/10.22214/ijraset.2022.46924.

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Abstract: Heterocyclic chemistry is very important aspects in organic chemistry. Heterocyclic system consists of one or more heteroatoms like nitrogen, oxygen, sulphur, etc with hydrogen atoms. The system can be classified as saturated as well as non saturated system or hydrocarbons. Another classification of this ring system is divided in some categories like three-membered, four-membered, five-membered, six-memebered, seven-membered, fused heterocyclics etc. Some compounds under this cklassification are acidic or basic in nature. Examples of heterocyclic compounds are Pyrole, Furan, Thiophen
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Shaikh, Ansar R., Mazahar Farooqui, R. H. Satpute, and Syed Abed. "Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 424–28. http://dx.doi.org/10.22270/jddt.v8i6-s.2156.

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Heterocyclic compounds have a role in most fields of sciences such as medicinal chemistry, biochemistry also another area of sciences. More than 90% of new drugscontain heterocycles and the interface between chemistry and biology, at which so much new scientific insight, discovery and application is taking place is crossed by heterocyclic compounds. Compounds derived from heterocyclic rings in pharmacy, medicine, agriculture, plastic, polymer and other fields.Most active heterocycles that have shown considerable biological actions as antifungal, anti-inflammatory, antibacterial, anticonvulsant
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Slivka, Mikhailo, and Mikhailo Onysko. "The Use of Electrophilic Cyclization for the Preparation of Condensed Heterocycles." Synthesis 53, no. 19 (2021): 3497–512. http://dx.doi.org/10.1055/s-0040-1706036.

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AbstractCondensed heterocycles are well-known for their excellent biological effects and they are undeniably important compounds in organic chemistry. Electrophilic cyclization reactions are widely used for the synthesis of mono-heterocyclic compounds. This review highlights the utility of electrophilic cyclization reactions as an effective generic tool for the synthesis of various condensed heterocycles containing functional groups that are able to undergo further chemical transformations, such as nucleophilic substitution, elimination, re-cyclization, cleavage, etc. This review describes the
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Cui, Hai-Lei. "Recent Advances in DMSO-Based Direct Synthesis of Heterocycles." Molecules 27, no. 23 (2022): 8480. http://dx.doi.org/10.3390/molecules27238480.

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Besides serving as a low-toxicity, inexpensive and easily accessible solvent, dimethyl sulfoxide (DMSO) has also been extensively used as a versatile reagent for the synthesis of functionalized molecules. Dimethyl sulfoxide can not only be utilized as a carbon source, a sulfur source and an oxygen source, but also be employed as a crucial oxidant enabling various transformations. The past decade has witnessed a large number of impressive achievements on the direct synthesis of heterocycles as well as modifications of heterocyclic compounds by applying DMSO as a reagent. This review summarized
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Adak, Laksmikanta, and Tubai Ghosh. "Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles." Current Organic Chemistry 24, no. 22 (2020): 2634–64. http://dx.doi.org/10.2174/1385272824999200714102103.

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Heterocyclic compounds are the largely diverse organic molecules and find prevalent applications in the fine chemical industry, medicinal chemistry and agricultural science. They are also among the most commonly bearing frameworks in numerous drugs and pharmaceutical substances. Therefore, the development of convenient, efficient and environmentally benign methods to produce various types of heterocyclic compounds is an attractive area of research. For the synthesis and functionalization of heterocycles, enormous achievements have been attributed over the past decades. Recently, ironcatalyzed
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Shekarkhand, Marzieh, Karim Zare, Majid Monajjemi, Elham Tazikeh-Lemeski, and Masoumeh Sayadian. "Computational study of heterocyclic anticancer compounds through nbo method." Nexo Revista Científica 35, no. 01 (2022): 367–81. http://dx.doi.org/10.5377/nexo.v35i01.13982.

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In the present study NBO method contain the HOMO and the LUMO energies are calculated for 10 different heterocycles anticancer drug using B3LYP/6-31G(d,p). Frontier molecular orbitals (HOMO and LUMO) and Molecular Electrostatic Potential map of the compound was produced by using the π stacking of structures and anticancer activity of molecules. The NBO analysis was suggested that the molecular system contains π- π interaction, strong conjugative interactions and the molecule become more polarized owing to the movement of π-electron cloud from donor to acceptor. NBO, HOMO and LUMO energies, wer
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Dissertations / Theses on the topic "Heterocyclic compoundis"

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Locke, Julie Myree, University of Western Sydney, College of Health and Science, and School of Biomedical and Health Sciences. "Synthetic and conformational studies of hexahydropyrimidines and related heterocycles." THESIS_CHS_BHS_Locke_J.xml, 2003. http://handle.uws.edu.au:8081/1959.7/638.

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This thesis explores the synthesis and conformational behaviour of hexahydropyrimidines and related heterocycles, with particular emphasis on 5- hyrdohexahydropyrimidines. The conformational behaviour of these compounds was investigated using dynamic NMR spectroscopy, molecular modelling techniques and X-ray crystal structure analysis. The conformational behaviour of 5- hyrdohexahydropyrimidine, hexahydropyrimidine and their analogous oxygen compounds as well as a series of hexahydropyrimidines with various exocyclic substituents, were examined. The preferred conformations of all these compoun
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Fletcher, Kristin A. "Mobile Order Theory as Applied to Polycyclic Aromatic Heterocycles." Thesis, University of North Texas, 1997. https://digital.library.unt.edu/ark:/67531/metadc278994/.

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Experimental mole fraction solubilities of benzil, thianthrene, trans-stilbene, thioxanthen-9-one, diphenyl sulfone and dibenzothiophene sulfone are determined in pure noncomplexing and complexing solvents. Predicted solubility values are calculated for benzil, thianthrene, trans-stilbene and thioxanthen-9-one using expressions derived from Mobile Order theory. Large deviations between experimental and predicted solubilities in alcohol solvents exist, therefore optimized solute - solvent association constants are determined. Previously measured thianthrene solubilities in five binary alkane +
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Armugam, S. "Studies on N-Heterocyclic Compounds." Thesis, Indian Institute of Science, 1994. http://hdl.handle.net/2005/108.

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The thesis entitled "Studies on N-Hetero cyclic Compounds: (a) Reaction of 5,6,7,8-Tetrahydroisoquinolines with Vilsmeier Reagent and (b) Amide Induced in situ Alkylation of 5,6-Dihydroisoquinolines" is presented in two parts. Part I involves a study of the Vilsmeier reaction of 4-cyano-1,3-dihydroxy-5,6,7,8 tetrahydroisoquinoline derivatives, while Part II concerns the in situ alkylation of l-alkyl-4-cyano-3-methoxy-5,6- dihydroisoquinolines in presence of KNH2/liq.NH3.
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Hu, Gang. "Conducting polymers from heterocyclic compounds." Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240331.

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Nyoni, Dubekile. "Application of the Baylis-Hillman methodology in the construction of novel heterocyclic derivatives." Thesis, Rhodes University, 2008. http://eprints.ru.ac.za/1134/.

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Locke, Julie Myree. "Synthetic and conformational studies of hexahydropyrimidines and related heterocycles." Thesis, View thesis, 2003. http://handle.uws.edu.au:8081/1959.7/638.

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This thesis explores the synthesis and conformational behaviour of hexahydropyrimidines and related heterocycles, with particular emphasis on 5- hyrdohexahydropyrimidines. The conformational behaviour of these compounds was investigated using dynamic NMR spectroscopy, molecular modelling techniques and X-ray crystal structure analysis. The conformational behaviour of 5- hyrdohexahydropyrimidine, hexahydropyrimidine and their analogous oxygen compounds as well as a series of hexahydropyrimidines with various exocyclic substituents, were examined. The preferred conformations of all these compoun
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Miah, Soyfur. "The metallocarbene route to heterocyclic compounds." Thesis, Loughborough University, 1997. https://dspace.lboro.ac.uk/2134/26972.

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Wilson, Jennifer M. "Synthesis of biologically active heterocyclic compounds." Thesis, University of Glasgow, 2007. http://theses.gla.ac.uk/45/.

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More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are required that are more effective and selective. Nitrogen mustard alkylating agents crosslink DNA inhibiting transcription and replication. Use of the mustard pharmacophore as part of a macrocycle allows metal complexation and produces a prodrug. Hypoxic tumour cells have increased concentrations of reductase enzymes which could lead to reduction of the complex in situ and release of a cytotoxic drug. Human African Trypanosomiasis is commonly known as Sleeping Sickness and affects over 36 countries
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MacDonald, Ranald John. "Novel routes to heterocyclic Azo compounds." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5787.

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The potential use of electron-deficient heterocyclic azo compounds as inkjet dyes was explored. 2-Nitrosopyridine could be used to form a series of azo compounds via the Mills’ reaction with electron-rich aromatic amines. Conditions for this process were optimised by varying solvent and pH. In the presence of ethers, 2-nitrosopyridine is quickly reduced to azoxypyridine. This reaction follows first order kinetics; diethyl and diisopropyl ether react at similar rates, whereas cyclic ethers such as THF are far slower. Organic bases such as Hunigs base were also found to promote formation of azox
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Jamalis, Joazaizulfazli. "Synthesis of heterocyclic containing oxygen compounds." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529847.

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Books on the topic "Heterocyclic compoundis"

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Petrov, Viacheslav A., ed. Fluorinated Heterocyclic Compounds. John Wiley & Sons, Inc., 2009. http://dx.doi.org/10.1002/9780470528952.

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Hans, Suschitzky, Meth-Cohn Otto, and Royal Society of Chemistry, eds. Heterocyclic chemistry. Royal Society of Chemistry, 1985.

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Hans, Suschitzky, and Royal Society of Chemistry, eds. Heterocyclic chemistry. The Royal Society of Chemistry, 1986.

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Krygowski, Tadeusz M., and Michał K. Cyrański, eds. Aromaticity in Heterocyclic Compounds. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-68343-8.

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Newkome, George R., ed. Chemistry of Heterocyclic Compounds. John Wiley & Sons, Inc., 1985. http://dx.doi.org/10.1002/9780470186701.

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Brown, D. J., R. F. Evans, W. B. Cowden, and M. D. Fenn, eds. Chemistry of Heterocyclic Compounds. John Wiley & Sons, Inc., 1985. http://dx.doi.org/10.1002/9780470186770.

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Brown, D. J., ed. Chemistry of Heterocyclic Compounds. John Wiley & Sons, Inc., 1988. http://dx.doi.org/10.1002/9780470186893.

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Delia, Thomas J., and John C. Warner, eds. Chemistry of Heterocyclic Compounds. John Wiley & Sons, Inc., 1991. http://dx.doi.org/10.1002/9780470186909.

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Jones, Gurnos, and John V. Greenhill, eds. Chemistry of Heterocyclic Compounds. John Wiley & Sons, Inc., 1990. http://dx.doi.org/10.1002/9780470187043.

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Kathawala, F. G., Gary M. Coppola, and Herbert F. Schuster, eds. Chemistry of Heterocyclic Compounds. John Wiley & Sons, Inc., 1990. http://dx.doi.org/10.1002/9780470187128.

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Book chapters on the topic "Heterocyclic compoundis"

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Gooch, Jan W. "Heterocyclic Compound." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_5914.

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Paulus, Wilfried. "Heterocyclic N,S Compounds." In Microbicides for the Protection of Materials. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2118-7_15.

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Alvárez-Builla, Julio, and José Barluenga. "Heterocyclic Compounds: An Introduction." In Modern Heterocyclic Chemistry. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527637737.ch1.

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Brandsma, Lambert. "Metallation of Heterocyclic Compounds." In Preparative Polar Organometallic Chemistry. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-61517-7_6.

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Azam, Amir, and Subhash Mohan Agarwal. "Heterocyclic Lead Compounds Against Amebiasis." In Amebiasis. Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-55200-0_33.

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Ahluwalia, V. K. "Stereochemistry of Some Heterocyclic Compounds." In Stereochemistry of Organic Compounds. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84961-0_16.

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Tabaković, Ibro. "Anodic synthesis of heterocyclic compounds." In Topics in Current Chemistry. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/3-540-61454-0_71.

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Ata, Athar, and Samina Naz. "Synthesis of Bioactive Heterocyclic Compounds." In Greener Synthesis of Organic Compounds, Drugs and Natural Products. CRC Press, 2022. http://dx.doi.org/10.1201/9781003089162-8.

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Yamamoto, Yoshihiko, and Kenji Itoh. "Ruthenium-Catalyzed Synthesis of Heterocyclic Compounds." In Ruthenium Catalysts and Fine Chemistry. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/b94646.

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Paulus, Wilfried. "Erratum to: Heterocyclic N,S Compounds." In Microbicides for the Protection of Materials. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2118-7_25.

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Conference papers on the topic "Heterocyclic compoundis"

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Nowak, Kacper, Michal Grzelczak, Boguslaw Szlachetko, et al. "Terahertz investigations on some bi-heterocyclic compounds." In 2016 21st International Conference on Microwave, Radar and Wireless Communications (MIKON). IEEE, 2016. http://dx.doi.org/10.1109/mikon.2016.7492097.

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Pyrko, A. N. "ENVIRONMENTALLY FRIENDLY SYNTHESIS AND BIOLOGICAL TESTING FOR PESTICIDAL ACTIVITY OF HETEROCYCLIC ANALOGS OF STEROIDS." In SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2022. http://dx.doi.org/10.46646/sakh-2022-1-187-190.

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The aim of the study is the synthesis and testing for pesticidal activities of 2,3-dimethoxy-16,16-dimethyl-D-homo-8-azagona-1,3,5 (10),13-tetraene-12,17а-one and 2,3-dimethoxy-16,16-dimethyl-d-homo-8-azagona-1,3,5(10),13-tetraene-12-imino-17а-one hydrochloride which could become the basis of plant protection products. The first compound was obtained by condensation of 6,7-dimethoxy-2,3-dihydroisoquinoline with 2-acetyl-5.5-dimethylcyclohexane-1,3-dione. The second substance was synthesized by interaction of the first with ammonium chloride. The synthesized compounds were tested for certain ty
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Pausch, Axel E., Thomas Geelhaar, Eike Poetsch, and Ulrich Finkenzeller. "New fluorinated heterocyclic compounds for improved FLC mixtures." In SPIE/IS&T 1992 Symposium on Electronic Imaging: Science and Technology, edited by Paul S. Drzaic and Uzi Efron. SPIE, 1992. http://dx.doi.org/10.1117/12.60381.

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Ariunbold, Gombojav O., Bryan Semon, Surpiya Nagpal, and Yuri Rostovtsev. "Cooperative Emissions from Hydrogen-Bonded Heterocyclic Organic Compounds." In CLEO: Applications and Technology. OSA, 2020. http://dx.doi.org/10.1364/cleo_at.2020.aw4k.4.

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Biliavska, Liubov, Yulia Pankivska, Olga Povnitsa, et al. "Antiviral Activity of Fluorinated Heterocyclic Compounds." In 2nd International Electronic Conference on Medicinal Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecmc-2-a019.

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Stanovnik, Branko. "3-Dimethylaminopropenoates and Related Compounds in the Synthesis of Heterocyclic Systems and Heterocyclic Amino Acids." In The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01783.

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Glukhacheva, Vera, and Sergey Ilꞌyasov. "SYNTHESIS AND PROPERTIES OF NITRO DERIVATIES OF HETEROCYCLIC ANTRACENES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m729.aks-2019/97-99.

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Redda, Kinfe Ken, Madhavi Gangapuram, Mohammad A. Ghaffari, Suresh Eyunni, Nelly Mateeva, and Bereket Mochona. "Abstract 2229: Synthesis of heterocyclic compounds as anticancer agents." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2229.

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Schrader, Sigurd K., Paolo Imperia, Norbert Koch, Guenther Leising, and B. Falk. "Organic light-emitting devices based on new heterocyclic compounds." In SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, edited by Zakya H. Kafafi. SPIE, 1999. http://dx.doi.org/10.1117/12.372711.

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El Fattah, M. E. Abd, H. H. Abd Allah, and A. H. Soliman. "Synthesis and Biological Activity of Some New Heterocyclic Compounds." In The 14th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00495.

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Reports on the topic "Heterocyclic compoundis"

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Allcock, Harry R. Strained Inorganic Heterocyclic Compounds and their Conversion to Macrocycles and High Polymers. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada241414.

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Klubek, B. Microbial removal of organic sulfur from coal (bacterial degradation of sulfur-containing heterocyclic compounds). Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/7019091.

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Brel, Valery K. Development of the New Approaches in Designing of Fluoroorganic Derivatives Sulfur (Unsaturated, Heterocyclic, Aromatic Molecular Systems and Polyfunctional Organic Compounds). Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada447113.

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Klubek, B., and D. Clark. Microbial removal of organic sulfur from coal (bacterial degradation of sulfur-containing heterocyclic compounds): Final report, March 1--December 31, 1987. Office of Scientific and Technical Information (OSTI), 1988. http://dx.doi.org/10.2172/6462019.

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Klubek, Brian. Microbial removal of organic sulfur from coal (bacterial degradation of sulfur-containing heterocyclic compounds): Final report, January 1--December 31, 1988. Office of Scientific and Technical Information (OSTI), 1989. http://dx.doi.org/10.2172/6177644.

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Author, Not Given. (Comparison of the activity of subsurface and surface microorganisms and their anaerobic transformation of heterocyclic compounds): Progress report, July 1, 1987--June 30, 1989. Office of Scientific and Technical Information (OSTI), 1989. http://dx.doi.org/10.2172/6025469.

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Ozekin, K., R. D. Noble, and C. A. Koval. A theoretical analysis of the extraction of heterocyclic organic compounds from an organic phase using chemically mediated electrochemically modulated complexation in ion exchange polymer beads. Office of Scientific and Technical Information (OSTI), 1991. http://dx.doi.org/10.2172/6181074.

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Adams, Richard D. Studies of the Transformations of Sulfur Containing Heterocycles by Transition Metal Cluster Compounds. Final Report, June 1, 1995 - October 31, 1999. Office of Scientific and Technical Information (OSTI), 2001. http://dx.doi.org/10.2172/803362.

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