Log in

Relevant bibliographies by topics / Heterocyclic thiosemicarbazones

Contents

Journal articles
Dissertations / Theses
Book chapters
Conference papers

Academic literature on the topic 'Heterocyclic thiosemicarbazones'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Heterocyclic thiosemicarbazones.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Heterocyclic thiosemicarbazones"

1

Rekiba, Nawel, Abdelmadjid Benmohammed, Sofiane Khanoussi, Ayada Djafri, and Jérôme Thibonnet. "Synthesis and Characterization of Novel Thiazolidinones and Thioxothiazolidinones Derived from Substituted Indole." Molbank 2021, no. 4 (2021): M1284. http://dx.doi.org/10.3390/m1284.

Full text

Abstract:

Based on recent discoveries concerning the numerous biological properties of thiazolidinones and thiosemicarbazones, new N-substituted heterocyclic derivatives have been designed by combining the indole ring with thioxothiazolidinone, thiazolidinone or thiosemicarbazone. Thus, a series of new thioxothiazolidinone, thiazolidinone, or thiosemicarbazone derivatives bearing indole-based moiety have been designed, synthesized, and developed in good yields.

APA, Harvard, Vancouver, ISO, and other styles

2

Nagoor Meeran M and Narayanan Ravisankar. "Synthesis and characterization of substituted acetophenone-4, 4-dimethyl-3-thiosemicarbazone derivatives with an evaluation of antimicrobial and antioxidant activities." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 7192–97. http://dx.doi.org/10.26452/ijrps.v11i4.3844.

Full text

Abstract:

Thiosemicarbazones are organic compounds; these are widely used in the medical field. It is primarily in the manufacture of pharmaceutical drugs and bio molecules. These compounds have the azomethine functional group (-N=CH-) used to derive organic open chain and heterocyclic compounds. Thiosemicarbazones are similar to semicarbazones, and carbonyl group oxygen is replaced by sulphur. Thiosemicarbazone contains nitrogen and sulfur atoms, so they are used as ligands in coordination chemistry and form metal complexes. Thiosemicarbazone and its metal complexes are used in a variety of ways. It is

APA, Harvard, Vancouver, ISO, and other styles

3

P., UMAPATHY, P. BUDHKAR A., and S. DORAI C. "Synthesis and Spectral Studies on Metal Chelates of Heterocyclic Carboxaldehyde Thiosemicarbazones." Journal of Indian Chemical Society Vol. 63, Aug 1986 (1986): 714–21. https://doi.org/10.5281/zenodo.6295026.

Full text

Abstract:

National Chemical Laboratory, Poona-411 008 <em>Manuscript received 18 September 1984, </em>revised <em>16 August 1985, accepted 12 August 1986</em> Square-planar neutral metal chelates of aldehyde thiosemicarbazones of the type ML,. where M=Ni<sup>II</sup>, Pd<sup>lI</sup> or Pt<sup>II</sup> and HL =thiosemicarbazone or 4-phenyl- or 4-methytthlosemicarbazone of 2-furaldehyde or thiopbene-2-carboxaldehyde or <em>o</em>-nitrobenzaldehyde. have been synthesised and characterised. Jr. uv-visible. <sup>1</sup>H and <sup>13</sup>C nmr and polarographic techniques have been utilised t

APA, Harvard, Vancouver, ISO, and other styles

4

Vandresen, Fabio, Sabrina Alencar de Almeida-Batista, Maria Eduarda Bueno Caldeira, et al. "Antitumor and antileishmanial activities of limonene-thiosemicarbazones bearing heterocycles nucleous." Research, Society and Development 11, no. 5 (2022): e11711528152. http://dx.doi.org/10.33448/rsd-v11i5.28152.

Full text

Abstract:

In the present study, we provided the synthesis of a series of R-(+)- and S-(-)-limonene-based thiosemicarbazones containing different pentacyclic heterocyclic nucleus moiety focused in the search of novel antitumor and antileishmanial agents. In the antitumor assay, the derivative imidazole of S-(-)-limonene 8 was the most active compound, especially for U-251, UACC-62 and K562 human tumor cell lines with GI50 ranging from 1.0 to <0.25 µg.mL-1. On the other hand, the imidazole-thiosemicarbazone of R-(+)-limonene 4 was the most promising derivative against the promastigote form of L. amazon

APA, Harvard, Vancouver, ISO, and other styles

5

Koshelev, Vladimir N., Olga V. Primerova, Stepan V. Vorobyev, Anna S. Stupnikova, and Ludmila V. Ivanova. "Synthesis and Antioxidant Activity of Novel Thiazole and Thiazolidinone Derivatives with Phenolic Fragments." Applied Sciences 13, no. 24 (2023): 13112. http://dx.doi.org/10.3390/app132413112.

Full text

Abstract:

In this work, a series of thiosemicarbazones with phenol fragments were used as starting compounds for the synthesis of new effective antioxidants containing both a phenol substituent and a heterocyclic fragment: thiazole and thiazolidinone. To determine the most stable conformation of thiosemicarbazone, a potential energy scan was used, along with NOESY NMR spectroscopy data. A number of thiazole derivatives were obtained due the interaction of thiosemicarbazones with several bromoketones: bromoacetophenone, bromodimedone, and bromoacetylcoumarin. The product yields varied from 71 to 94%. Thi

APA, Harvard, Vancouver, ISO, and other styles

6

Haribabu, Jebiti, Manoharan Muthu Tamizh, Chandrasekar Balachandran, et al. "Synthesis, structures and mechanistic pathways of anticancer activity of palladium(ii) complexes with indole-3-carbaldehyde thiosemicarbazones." New Journal of Chemistry 42, no. 13 (2018): 10818–32. http://dx.doi.org/10.1039/c7nj03743k.

Full text

Abstract:

Palladium(ii) complexes featuring bidentate heterocyclic thiosemicarbazones have been synthesized, characterized and evaluated for their biomolecular interactions. The complexes induced in vitro anticancer activity through apoptosis.

APA, Harvard, Vancouver, ISO, and other styles

7

Mathuber, Marlene, Sonja Hager, Bernhard K. Keppler, Petra Heffeter, and Christian R. Kowol. "Liposomal formulations of anticancer copper(ii) thiosemicarbazone complexes." Dalton Transactions 50, no. 44 (2021): 16053–66. http://dx.doi.org/10.1039/d1dt02763h.

Full text

Abstract:

Liposomal formulations of copper(ii) complexes of α-N-heterocyclic thiosemicarbazones (triapine and COTI-2) were synthesized, characterized and biologically investigated, with the aim to enhance their plasma half-life time and tumor accumulation.

APA, Harvard, Vancouver, ISO, and other styles

8

García, Cybele C., Beatriz N. Brousse, Marla J. Carlucci, et al. "Inhibitory Effect of Thiosemicarbazone Derivatives on Junin Virus Replication In Vitro." Antiviral Chemistry and Chemotherapy 14, no. 2 (2003): 99–105. http://dx.doi.org/10.1177/095632020301400205.

Full text

Abstract:

The inhibitory effect of several thiosemicarbazones (TSCs), synthesized from aromatic ketones and terpenones, and their heterocyclic thiadiazoline (TDZ) derivatives, was investigated against Junin virus (JUNV), an arenavirus agent of Argentine haemorrhagic fever. From the 25 compounds tested, six compounds belonging to the TSC group were found to be selective inhibitors of JUNV, with EC50 values determined by a virus yield inhibition assay in the range 3.4–12.5 μM, and selectivity indices greater than 10. By contrast, most of the TDZs obtained by heterocyclization of the TSCs were not active a

APA, Harvard, Vancouver, ISO, and other styles

9

Shakya, Bhushan, and Paras Nath Yadav. "Thiosemicarbazones as Potent Anticancer Agents and their Modes of Action." Mini-Reviews in Medicinal Chemistry 20, no. 8 (2020): 638–61. http://dx.doi.org/10.2174/1389557519666191029130310.

Full text

Abstract:

: Thiosemicarbazones (TSCs) are a class of Schiff bases usually obtained by the condensation of thiosemicarbazide with a suitable aldehyde or ketone. TSCs have been the focus of chemists and biologists due to their wide range of pharmacological effects. One of the promising areas in which these excellent metal chelators are being developed is their use against cancer. TSCs have a wide clinical antitumor spectrum with efficacy in various tumor types such as leukemia, pancreatic cancer, breast cancer, non-small cell lung cancer, cervical cancer, prostate cancer and bladder cancer. To obtain bett

APA, Harvard, Vancouver, ISO, and other styles

10

Fonseca, Nayara Cristina, Luana Faria da Cruz, Filipe da Silva Villela, et al. "Synthesis of a Sugar-Based Thiosemicarbazone Series and Structure-Activity Relationship versus the Parasite Cysteine Proteases Rhodesain, Cruzain, and Schistosoma mansoni Cathepsin B1." Antimicrobial Agents and Chemotherapy 59, no. 5 (2015): 2666–77. http://dx.doi.org/10.1128/aac.04601-14.

Full text

Abstract:

ABSTRACTThe pressing need for better drugs against Chagas disease, African sleeping sickness, and schistosomiasis motivates the search for inhibitors of cruzain, rhodesain, andSchistosoma mansoniCB1 (SmCB1), the major cysteine proteases fromTrypanosoma cruzi,Trypanosoma brucei, andS. mansoni, respectively. Thiosemicarbazones and heterocyclic analogues have been shown to be both antitrypanocidal and inhibitory against parasite cysteine proteases. A series of compounds was synthesized and evaluated against cruzain, rhodesain, and SmCB1 through biochemical assays to determine their potency and st

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Heterocyclic thiosemicarbazones"

1

Budhkar, A. P. "Studies on thiosemicarbazones, some nitrogen, sulphur containing heterocyclic ligands and their metal complexes." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1987. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3296.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Ling, Lin Guan, and 林冠伶. "Studies on the syntheses and pharmacological properties of sydnonyl-snbstituted heterocyclic derivatives and metal complexes derived from thiosemicarbazones." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/50253250321027565810.

Full text

Abstract:

碩士<br>南台科技大學<br>化學工程與材枓工程系<br>95<br>Many heterocyclic compounds and thiosemicarbazones metal complexes have been known for special physiological activity. Therefore, sydnonyl-substituted heterocycles and sydnonyl substituted thiosemicarbazones metal complexes were synthesized in this study. The text is divided into three major parts. In the first part, the syntheses of many kinds of heterocycles were studied and. The sydnonyl-substituted thiazolidine derivatives were produced in high yields by the modified Knoevenagel condensation of 3-aryl-4-formylsydnones with thiazolidine -2,4-dione , 2-thi

APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Heterocyclic thiosemicarbazones"

1

West, Douglas X., Subhash B. Padhye, and Pramila B. Sonawane. "Structural and physical correlations in the biological properties of transition metal heterocyclic thiosemicarbazone and S-alkyldithiocarbazate complexes." In Complex Chemistry. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/3-540-53499-7_1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Liu, Mao-Chin, Tai-Shun Lin, and Alan C. Sartorelli. "1 Chemical and Biological Properties of Cytotoxic α-(N)-Heterocyclic Carboxaldehyde Thiosemicarbazones." In Progress in Medicinal Chemistry. Elsevier, 1995. http://dx.doi.org/10.1016/s0079-6468(08)70451-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

"Gold Complexes as Antiparasitic Agents." In The Therapeutic Potential of Gold Complexes. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781837678891-00067.

Full text

Abstract:

The impetus for the rational design and development of antiparasitic gold complexes started with the study of the antimalarial properties of gold(iii) complexes of the antimalarial agents primaquine and amodiaquine. The complexes showed interesting activity against Plasmodium falciparum, one of the causative parasites for malaria. The last few decades have witnessed a huge increase in the rational design of gold complexes for the development of antiparasitic drugs and several gold complexes with a plethora of ligand systems have displayed exciting antiparasitic properties. This chapter focuses

APA, Harvard, Vancouver, ISO, and other styles

4

Aggarwal, P., and M. W. P. Bebbington. "Cyclization of Silyl-Substituted Thiosemicarbazone Acetic Acid Esters." In Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-117-00243.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Heterocyclic thiosemicarbazones"

1

Zhupikova, O. A., O. I. Yarovaya, M. K. Marenina, et al. "SYNTHESIS OF THIOSEMICARBOSONES WITH ACTIVITY AGAINST SARS-COV-2 AND H1N1 INFLUENZA VIRUSES." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-185.

Full text

Abstract:

In this work, new thiosemicarbazones were synthesized based on the corresponding heterocyclic aldehydes and their antiviral properties were studied. The substances were obtained as colored solids in yields ranging from 82 to 94 %. It has been shown that 2-((5-(p-tolyl)isoxazol-3-yl)methylene)hydrazine-1-carbothiamide exhibits activity against SARS-CoV-2 and H1N1 influenza viruses in the micromolar range and is not toxic on the tested cell lines.

APA, Harvard, Vancouver, ISO, and other styles

2

Sousa, Rui P. C. L., Susana P. G. Costa, Rita B. Figueira, and Maria Manuela M. Raposo. "Synthesis and Chemosensory Studies of a Heterocyclic Thiosemicarbazone as a New Tributyltin Optical Chemosensor." In International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2022. http://dx.doi.org/10.3390/ecsoc-26-13540.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!