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Journal articles on the topic 'HEVs'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Sridhar, Siddharth, Jade L. L. Teng, Tsz-Ho Chiu, Susanna K. P. Lau, and Patrick C. Y. Woo. "Hepatitis E Virus Genotypes and Evolution: Emergence of Camel Hepatitis E Variants." International Journal of Molecular Sciences 18, no. 4 (2017): 869. https://doi.org/10.5281/zenodo.13530581.

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(Uploaded by Plazi for the Bat Literature Project) Hepatitis E virus (HEV) is a major cause of viral hepatitis globally. Zoonotic HEV is an important cause of chronic hepatitis in immunocompromised patients. The rapid identification of novel HEV variants and accumulating sequence information has prompted significant changes in taxonomy of the family Hepeviridae. This family includes two genera: Orthohepevirus, which infects terrestrial vertebrates, and Piscihepevirus, which infects fish. Within Orthohepevirus, there are four species, A–D, with widely differing host range. Orthohepevirus A cont

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Sridhar, Siddharth, Jade L. L. Teng, Tsz-Ho Chiu, Susanna K. P. Lau, and Patrick C. Y. Woo. "Hepatitis E Virus Genotypes and Evolution: Emergence of Camel Hepatitis E Variants." International Journal of Molecular Sciences 18, no. 4 (2017): 869. https://doi.org/10.5281/zenodo.13530581.

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(Uploaded by Plazi for the Bat Literature Project) Hepatitis E virus (HEV) is a major cause of viral hepatitis globally. Zoonotic HEV is an important cause of chronic hepatitis in immunocompromised patients. The rapid identification of novel HEV variants and accumulating sequence information has prompted significant changes in taxonomy of the family Hepeviridae. This family includes two genera: Orthohepevirus, which infects terrestrial vertebrates, and Piscihepevirus, which infects fish. Within Orthohepevirus, there are four species, A–D, with widely differing host range. Orthohepevirus A cont

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Rudova, N. G., O. S. Solodiankin, and O. Yu Lymanska. "Comparison of primer and probe sets for Hepatitis E virus detection by real time PCR." Veterinary Medicine: inter-departmental subject scientific collection, no. 108 (December 22, 2022): 16–21. https://doi.org/10.36016/vm-2022-108-3.

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Hepatitis E virus (HEV) infects humans and several mammals and it has eight genotypes (HEV1–HEV8). HEV1–HEV4 is the causative agent of hepatitis E in humans. HEV5–HEV6 was detected only in wild boar in Japan. HEV7–HEV8 was detected in camels. HEV3–HEV4 is characterized by zoonotic potential and main natural reservoirs for this virus are swines and wild boars. Besides, HEV3 was detected in deers, dolphins, rabbits, cattle, goats that is additional risk for virus interspecies transmission from domestic animals to humans. In this paper two primer and probe sets for HEV detection by real time PCR

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Lymanska, O. Yu. "Design of primer and linear probe sets for swine and wild boar HEV detection by PCR." Veterinary Medicine: inter-departmental subject scientific collection, no. 110 (October 23, 2024): 65–70. https://doi.org/10.36016/vm-2024-110-9.

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Hepatitis E virus (HEV) infects humans and several mammals and it has 8 genotypes (HEV1 HEV8). HEV1 4 is the causative agent of Hepatitis E in humans. HEV5 6 was detected only in wild boar in Japan, HEV7 8 was detected in camels. HEV3 4 is characterized by zoonotic potential. Swines and wild boars are main natural reservoirs for this virus. Besides, HEV 3 was detected in deers, dolphins, rabbits, cattle, goats that is additional risk for virus interspecies transmission from domestic animals to humans. Availability of mismatched nucleotides in the complexes of primer/probe with viral targets wa

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Kogami, Akiya, Mana Fukushima, Hitomi Hoshino, et al. "The Conspicuousness of High Endothelial Venules in Angioimmunoblastic T-cell Lymphoma Is Due to Increased Cross-sectional Area, Not Increased Distribution Density." Journal of Histochemistry & Cytochemistry 69, no. 10 (2021): 645–57. http://dx.doi.org/10.1369/00221554211048551.

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Angioimmunoblastic T-cell lymphoma (AITL) is a T-cell lymphoma of follicular helper T-cell origin. Histologically, neoplastic T-cells proliferate to form clusters adjacent to or between arborizing high endothelial venules (HEVs). HEVs in normal lymph nodes express sulfated glycans called peripheral lymph node addressin (PNAd); however, it remains unclear whether PNAd is also expressed on HEVs in AITL. Furthermore, although it is widely accepted that HEVs are conspicuous in AITL due to their proliferation, quantitative histological support for this concept is lacking. To investigate these issue

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Greenwood, Jessica L. J., Junji Lin, Danita Arguello, Trever Ball, and Janet M. Shaw. "Healthy Eating Vital Sign: A New Assessment Tool for Eating Behaviors." ISRN Obesity 2012 (July 22, 2012): 1–7. http://dx.doi.org/10.5402/2012/734682.

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Introduction. Most dietary questionnaires are not created for use in a clinical setting for an adult health exam. We created the Healthy Eating Vital Sign (HEVS) to assess eating behaviors associated with excess weight. This study investigated the validity and reliability of the HEVS. Methods. Using a cross-sectional study design, participants responded to the HEVS and the Block Food Frequency Questionnaire (BFFQ). We analyzed the data descriptively, and, with Pearson’s correlation and Cronbach coefficient alpha. Results. We found moderate correlation (rho>0.3) between multiple items of the

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Kasturi, Mahajan, and Gawade Shashank. "A Comprehensive Review on Control Solutions of Hybrid Energy Storage System (HESS) for Electric Vehicles." International Journal of Innovative Science and Research Technology 8, no. 2 (2023): 1612–16. https://doi.org/10.5281/zenodo.7707002.

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- In the near future, electric vehicles with superior energy sources will become more widespread. This review paper discusses an overview of hybrid electric vehicles (HEVs) with an emphasis on battery cell technologies, topological configurations of HESS, and its control techniques. The Energy Management Strategy (EMS) of HESS with a fuel cell (FC), a supercapacitor, and an ultra-capacitor uses in HEVs. The primary goal is to increase the battery system's efficiency and effective use under secure operating circumstances. According to a review, some researchers have used battery-UC HESS as

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Kanemitsu, Naotoshi, Yukihiko Ebisuno, Toshiyuki Tanaka, et al. "CXCL13 is an arrest chemokine for B cells in high endothelial venules." Blood 106, no. 8 (2005): 2613–18. http://dx.doi.org/10.1182/blood-2005-01-0133.

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Abstract Chemokine receptor signaling is critical for lymphocyte trafficking across high endothelial venules (HEVs), but the exact mode of action of individual chemokines expressed in the HEVs is unclear. Here we report that CXCL13, expressed in a substantial proportion of HEVs in both lymph nodes (LNs) and Peyer patches (PPs), serves as an arrest chemokine for B cells. Whole-mount analysis of mesenteric LNs (MLNs) showed that, unlike T cells, B cellsa dhere poorly to the HEVs of CXCL13–/– mice and that B-cell adhesion is substantially restored in CXCL13–/– HEVs when CXCL13 is added to the MLN

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Roberts, Jason A., Tuckweng Kok, and Bruce R. Thorley. "New approaches to enterovirus identification." Microbiology Australia 31, no. 3 (2010): 138. http://dx.doi.org/10.1071/ma10138.

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The human enteroviruses (HEVs) are members of the Picornaviridae family and cause a diverse range of diseases from respiratory illness to paralysis. Historically, HEVs were isolated in cell culture and subtype identification was by neutralisation using specific antisera. Currently, diagnostic virology laboratories use nucleic-acid-based tests to detect and identify HEVs in clinical specimens.

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Wami, Ashenafi Alemu, Gadissa Bedada Hundie, Rozina Ambachew, et al. "High rate of human enteroviruses among clinically suspected meningitis cases at selected Hospitals in Addis Ababa, Ethiopia." PLOS ONE 16, no. 11 (2021): e0258652. http://dx.doi.org/10.1371/journal.pone.0258652.

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Background Because of limited infrastructure and skilled human capital, the etiology of meningitis is rarely identified in developing countries like Ethiopia. This results in unnecessary antibiotics use, economic crisis, hospitalization, and related nosocomial infections. Thus, we aimed to assess the epidemiology of human enteroviruses (HEVs) among clinically suspected meningitis cases in Addis Ababa, Ethiopia. Method A cross-sectional study was conducted from January to August 2020 at selected Hospitals in Addis Ababa, Ethiopia. Reverse transcriptase-polymerase chain reaction (RT-PCR) was con

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Matsumoto, Ken’ichi, Yui Nakamine, Sunyong Eom, and Hideki Kato. "Demographic, Social, Economic, and Regional Factors Affecting the Diffusion of Hybrid Electric Vehicles in Japan." Energies 14, no. 8 (2021): 2130. http://dx.doi.org/10.3390/en14082130.

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The transportation sector is a major contributor to carbon dioxide emissions, and the resulting climate change. The diffusion of alternative fuel vehicles, including hybrid electric vehicles (HEV), is an important solution for these issues. This study aimed to evaluate the factors affecting the ownership ratio of HEVs, particularly passenger vehicles, and the regional differences in the purchase of HEVs in Japan. This study performed a fixed-effects regression analysis with panel data for 47 prefectures during the period 2005–2015 to evaluate the factors affecting the HEV ownership ratio and c

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Hong, Soon Auck, Hye Won Hwang, Min Kyoon Kim, et al. "High Endothelial Venule with Concomitant High CD8+ Tumor-Infiltrating Lymphocytes Is Associated with a Favorable Prognosis in Resected Gastric Cancer." Journal of Clinical Medicine 9, no. 8 (2020): 2628. http://dx.doi.org/10.3390/jcm9082628.

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CD8+ tumor-infiltrating lymphocytes (TILs) play a major role in antitumor immunity. High endothelial venules (HEVs) are related to diverse immune cells in solid tumors. We analyzed CD8+ and Foxp3+ TILs in combination with HEVs to determine their prognostic role in advanced gastric cancer (AGC). We enrolled 157 patients with AGC in this study. The densities of CD8+ TILs and Foxp3+ TILs were calculated using immunohistochemical staining. HEVs were evaluated by MECA-79 expression. HEVs were identified in 60 (38.2%) cases and was significantly associated with an increased number of CD8+ TILs (p =

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Ataman, B. C. Igbeka U. E. Emenime A. I. Kwasi-Effah C. C. &. Max-Eguakun F. "Role of Hybrid Electric Vehicles for Sustainable Transportation." NIPES Journal of Science and Technology Research 3, no. 4 (2021): 376–82. https://doi.org/10.5281/zenodo.8052169.

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<em>Hybrid electric vehicles (HEVs) have emerged as a promising solution to address the challenges of reducing greenhouse gas emissions, dependence on fossil fuels, and environmental impact in the automotive sector. This review paper examines the benefits, challenges, and future directions of HEVs in the context of sustainable transportation. It also discusses the environmental, economic, and social implications of HEVs and identifies potential areas for future research and development. By synthesizing the existing knowledge on HEVs, this paper aims to contribute to the understanding of their

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Wong, K. W., L. Y. Ng, C. H. Lim, D. K. S. Ng, and V. Andiappan. "Design of lubricants in electric and hybrid vehicles via computer-aided molecular design (CAMD) technique." IOP Conference Series: Materials Science and Engineering 1257, no. 1 (2022): 012029. http://dx.doi.org/10.1088/1757-899x/1257/1/012029.

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Abstract The market of electric and hybrid vehicles (EVs and HEVs) is expanding exponentially in recent years. It serves as a greener solution in the transportation sector as compared to internal combustion engine vehicles’ (ICEVs). Conventional lubricants used for ICEVs are not suitable for the EVs and HEVs as the latter operates on electric motors instead of combustion engines. Performance characteristics such as the electrical conductivity, thermal conductivity and copper compatibility are not considered by the ICEVs lubricant but are important for the EVs and HEVs. In this research, comput

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Jiang, Jielin, Qinting Jiang, Jinhui Chen, Xiaotong Zhou, Shengkai Zhu, and Tianyu Chen. "Advanced Power Management and Control for Hybrid Electric Vehicles: A Survey." Wireless Communications and Mobile Computing 2021 (January 6, 2021): 1–12. http://dx.doi.org/10.1155/2021/6652038.

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With the trend of low emissions and sustainable development, the demand for hybrid electric vehicles (HEVs) has increased rapidly. By combining a conventional internal combustion engine with one or more electric motors powered by a battery, HEVs have the advantages over traditional vehicles in better fuel economy and lower tailpipe emissions. Nevertheless, the power management strategies (PMSs) for conventional vehicles which mainly focus on the efficiency of internal combustion engine are no longer applicable due to the complex internal structure of HEVs. Hence, a large number of novel strate

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Yang, Fuyi, and Jianzhong Xu. "Homework Expectancy Value Scale: Measurement Invariance and Latent Mean Differences Across Gender." Journal of Psychoeducational Assessment 36, no. 8 (2017): 863–68. http://dx.doi.org/10.1177/0734282917714905.

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This study validated the Homework Expectancy Value Scale (HEVS) based on 918 middle school students from China. The factor analytic results showed that the HEVS consisted of two distinct yet related subscales: Expectancy and Value. Results further revealed that latent factor means for the HEVS were invariant across gender. Finally, consistent with theoretical expectations, Expectancy and Value were negatively correlated with homework distraction, and positively correlated with homework effort, emotion regulation, completion, and academic achievement.

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Janatpour, Mary J., Susan Hudak, Manjiri Sathe, Jonathon D. Sedgwick, and Leslie M. McEvoy. "Tumor Necrosis Factor–dependent Segmental Control of MIG Expression by High Endothelial Venules in Inflamed Lymph Nodes Regulates Monocyte Recruitment." Journal of Experimental Medicine 194, no. 9 (2001): 1375–84. http://dx.doi.org/10.1084/jem.194.9.1375.

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Monocytes recruited from the blood are key contributors to the nature of an immune response. While monocyte recruitment in a subset of immunopathologies has been well studied and largely attributed to the chemokine monocyte chemoattractant protein (MCP)-1, mechanisms mediating such recruitment to other sites of inflammation remain elusive. Here, we showed that localized inflammation resulted in an increased binding of monocytes to perifollicular high endothelial venules (HEVs) of lymph nodes draining a local inflammatory site. Quantitative PCR analyses revealed the upregulation of many chemoki

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M'Rini, Christine, Guiying Cheng, Colleen Schweitzer та ін. "A Novel Endothelial L-Selectin Ligand Activity in Lymph Node Medulla That Is Regulated by α(1,3)-Fucosyltransferase-IV". Journal of Experimental Medicine 198, № 9 (2003): 1301–12. http://dx.doi.org/10.1084/jem.20030182.

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Lymphocytes home to peripheral lymph nodes (PLNs) via high endothelial venules (HEVs) in the subcortex and incrementally larger collecting venules in the medulla. HEVs express ligands for L-selectin, which mediates lymphocyte rolling. L-selectin counterreceptors in HEVs are recognized by mAb MECA-79, a surrogate marker for molecularly heterogeneous glycans termed peripheral node addressin. By contrast, we find that medullary venules express L-selectin ligands not recognized by MECA-79. Both L-selectin ligands must be fucosylated by α(1,3)-fucosyltransferase (FucT)-IV or FucT-VII as rolling is

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Jung, Heejung. "Fuel Economy of Plug-In Hybrid Electric and Hybrid Electric Vehicles: Effects of Vehicle Weight, Hybridization Ratio and Ambient Temperature." World Electric Vehicle Journal 11, no. 2 (2020): 31. http://dx.doi.org/10.3390/wevj11020031.

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Hybrid electric vehicles (HEVs) and plug-in hybrid electric vehicles (PHEVs) are evolving rapidly since the introduction of Toyota Prius into the market in 1997. As the world needs more fuel-efficient vehicles to mitigate climate change, the role of HEVs and PHEVs are becoming ever more important. While fuel economies of HEVs and PHEVs are superior to those of internal combustion engine (ICE) powered vehicles, they are partially powered by batteries and therefore they resemble characteristics of battery electric vehicles (BEVs) such as dependence of fuel economy on ambient temperatures. It is

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Carlsen, Hege S., Guttorm Haraldsen, Per Brandtzaeg, and Espen S. Baekkevold. "Disparate lymphoid chemokine expression in mice and men: no evidence of CCL21 synthesis by human high endothelial venules." Blood 106, no. 2 (2005): 444–46. http://dx.doi.org/10.1182/blood-2004-11-4353.

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Abstract T-cell homing to secondary lymphoid tissues generally depends on chemokine-induced firm adhesion in high endothelial venules (HEVs) and is primarily mediated through the CC chemokine receptor 7 (CCR7) on lymphocytes. The CCR7 ligand designated CCL21 is considered the most important trigger because it appears constitutively expressed by murine HEVs. Surprisingly, when we analyzed human tissues, no CCL21 mRNA could be detected in HEVs. In fact, CCL21 mRNA was only expressed in extravascular T-zone cells and lymphatics, whereas immunostaining revealed CCL21 protein within HEVs. This sugg

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Sawada, Junko, Nobuyoshi Hiraoka, Rongsu Qi, et al. "Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer Survival." Cancer Immunology Research 10, no. 4 (2022): 468–81. http://dx.doi.org/10.1158/2326-6066.cir-21-0369.

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Abstract High endothelial venules (HEV) are specialized post-capillary venules that recruit naïve lymphocytes to lymph nodes. HEVs are essential for the development of adaptive immunity. HEVs can also develop in tumors where they are thought to be important for recruiting naïve T cells and B cells into the tumors and locally enhancing antitumor immunity by supporting the formation of tertiary lymphoid structures. Herein, we used comparative transcriptome analysis of human breast cancer to investigate genes differentially expressed between tumor-associated HEVs and the rest of the tumor vascula

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Henning, Golo, Lars Ohl, Tobias Junt, et al. "CC Chemokine Receptor 7–dependent and –independent Pathways for Lymphocyte Homing." Journal of Experimental Medicine 194, no. 12 (2001): 1875–81. http://dx.doi.org/10.1084/jem.194.12.1875.

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Cognate interaction of chemokine receptor CCR7 on lymphocytes with its ligands CCL19 and CCL21 expressed on high endothelial venules (HEVs) is essential for effective migration of T and B cells across HEVs into secondary lymphoid organs. Plt mice, which lack expression of CCL19 and CCL21-ser, both ligands for CCR7 on HEVs, as well as CCR7-deficient mice, have a defective cell migration and reduced homing of lymphocytes. FTY720, a novel immunosuppressant, causes a reduction of lymphocytes in peripheral blood and tissues and their sequestration into lymphoid tissues. In this study we demonstrate

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Zhao, Jianfu, Dan Zhang, Dongzhi Gao, Junjiang Bao, Xiaojun Jing, and Mingxuan Li. "Investigation of methods for measuring fuel economy and emissions of heavy-duty hybrid-electric vehicles (HEVs)." E3S Web of Conferences 360 (2022): 01002. http://dx.doi.org/10.1051/e3sconf/202236001002.

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Hybrid-electric vehicles can achieve low fuel consumption and emission by optimal combination of electrical energy and internal combustion engine power. There are four main test method of energy consumption and emission for heavy-duty HEVs, including traditional engine bench test, powertrain test, HILS and chassis dynamometer test. The tradition engine operating conditions are distinguished from that in HEVs, which can’t reflect the performance of HEVs. Powertrain test can achieve braking energy regeneration, but need bulky installation on testbed. HILS test solves the problem that the engine

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Song, Hyeinn, Kangwon Shin, and Fady M. A. Hassouna. "Is the High-Emission Vehicle Driving Area Restriction Policy an Effective Measure for Reducing Driving Distance? A Case Study of Busan, South Korea." Sustainability 16, no. 24 (2024): 11055. https://doi.org/10.3390/su162411055.

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Efforts to reduce air pollution by facilitating the transition to eco-friendly vehicles, particularly through driving restriction policies targeting high-emission vehicles (HEVs), play a crucial role in promoting environmental sustainability. Evaluating the effectiveness of the restriction in terms of reducing HEV driving mileage is essential for policy assessment and improvement. Moreover, given the overall decreasing trend in daily vehicle mileage, it remains uncertain whether the change in HEV driving distance can be directly attributed to the restriction policy. This study directly examine

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Gretz, J. Elizabeth, Christopher C. Norbury, Arthur O. Anderson, Amanda E. I. Proudfoot, and Stephen Shaw. "Lymph-Borne Chemokines and Other Low Molecular Weight Molecules Reach High Endothelial Venules via Specialized Conduits While a Functional Barrier Limits Access to the Lymphocyte Microenvironments in Lymph Node Cortex." Journal of Experimental Medicine 192, no. 10 (2000): 1425–40. http://dx.doi.org/10.1084/jem.192.10.1425.

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Lymph-borne, soluble factors (e.g., chemokines and others) influence lymphocyte recirculation and endothelial phenotype at high endothelial venules (HEVs) in lymph node cortex. Yet the route lymph-borne soluble molecules travel from the subcapsular sinus to the HEVs is unclear. Therefore, we injected subcutaneously into mice and rats a wide variety of fluorophore-labeled, soluble molecules and examined their distribution in the draining lymph nodes. Rather than percolating throughout the draining lymph node, all molecules, including microbial lipopolysaccharide, were very visible in the subcap

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Mionnet, Cyril, Stéphanie L. Sanos, Isabelle Mondor, et al. "High endothelial venules as traffic control points maintaining lymphocyte population homeostasis in lymph nodes." Blood 118, no. 23 (2011): 6115–22. http://dx.doi.org/10.1182/blood-2011-07-367409.

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Abstract Millions of lymphocytes enter and exit mammal lymph nodes (LNs) each day, accessing the parenchyma via high endothelial venules (HEVs) and egressing via lymphatics. Despite this high rate of cellular flux and the many entry and exit sites within a given LN, the number of lymphocytes present in a resting LN is extraordinary stable over time, raising the question of how this steady-state is maintained. Here we have examined the anatomic details of lymphocyte movement in HEVs, finding that HEVs create pockets within which lymphocytes reside for several minutes before entering the LN prop

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Stein, Jens V., Antal Rot, Yi Luo, et al. "The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules." Journal of Experimental Medicine 191, no. 1 (2000): 61–76. http://dx.doi.org/10.1084/jem.191.1.61.

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T cell homing to peripheral lymph nodes (PLNs) is defined by a multistep sequence of interactions between lymphocytes and endothelial cells in high endothelial venules (HEVs). After initial tethering and rolling via L-selectin, firm adhesion of T cells requires rapid upregulation of lymphocyte function–associated antigen 1 (LFA-1) adhesiveness by a previously unknown pathway that activates a Gαi-linked receptor. Here, we used intravital microscopy of murine PLNs to study the role of thymus-derived chemotactic agent (TCA)-4 (secondary lymphoid tissue chemokine, 6Ckine, Exodus-2) in homing of ad

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Babu, Jarapala Ramesh, Manas Ranjan Nayak, and B. Mangu. "A Peer Review of Hybrid Electric Vehicle Based on Step-Up Multi-input Dc-Dc Converter and renewable energy source." Journal of Physics: Conference Series 2089, no. 1 (2021): 012041. http://dx.doi.org/10.1088/1742-6596/2089/1/012041.

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Abstract Due to the rapid increase of environmental pollution caused by automobiles. To decrease pollution and to save our resources, there is an alternator to use an electric vehicle instead of a gasoline engine. The main drawback of a gasoline engine of compared to the electric vehicle can polluter noise efficiency durability. When it comes to durability, efficiency, and acceleration capabilities of electric vehicles, they are more impressive. The electric vehicles involve HEVs and BEVs. Generally, ultra-capacitor, solar Photovoltaic (PV) system, batters, regenerative braking systems and fly

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Zhu, Yuzheng, Xueyuan Li, Qi Liu, Songhao Li, and Yao Xu. "Review article: A comprehensive review of energy management strategies for hybrid electric vehicles." Mechanical Sciences 13, no. 1 (2022): 147–88. http://dx.doi.org/10.5194/ms-13-147-2022.

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Abstract. In order to prevent the aggravation of global environmental problems, all industries are facing the challenge of green development. In the automotive field, the development of “new-energy vehicles” (plug-in electric vehicles) is particularly necessary. Hybrid electric vehicles (HEVs) have been proven to be an efficient way of solving environmental and energy problems. As the core of HEVs, the energy management strategy (EMS) plays an important role in fuel economy, power performance, and drivability. However, considering the randomness of actual driving conditions, there are great ch

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Siwiec, D., R. Gawlik, and A. Pacana. "Sustainable design of products: Balancing quality, life cycle impact, and social responsibility." Advances in Production Engineering & Management 19, no. 4 (2024): 460–88. https://doi.org/10.14743/apem2024.4.519.

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The shift towards sustainable mobility has increased the demand for energy-efficient and environmentally friendly vehicles, such as Hybrid Electric Vehicles (HEVs). However, designing HEVs that simultaneously meet high product quality, minimize environmental impact, and adhere to social responsibility standards remains a complex challenge. This study presents a decision-making model aimed at integrating these key sustainability criteria into the design and improvement of HEVs. The model combines three indices: the Aggregated Quality Index (AQI), Environmental Impact Index (EII) based on Life C

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Priyadarshini, Aayushi, Shekhar Yadav, and Sandesh Patel. "Energy Management Schemes for Hybrid Electric Vehicles." International Energy Journal 25, no. 1B (2025): 293. https://doi.org/10.64289/iej.25.01b05.9638289.

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An internal combustion engine (ICE) and one or more electric motors are combined in hybrid electric vehicles (HEVs) to improve fuel economy and lower greenhouse gas emissions. This paper explores the various HEVs, such as series hybrids, parallel hybrids, series-parallel hybrids, and plug-in hybrid electric vehicles (PHEVs). Each types are described in terms of its components and operational modes, highlighting the advantages and challenges associated with each type. Key technological components of HEVs, such as the ICE, permanent magnet synchronous motors (PMSM), battery systems, and power el

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Umemoto, Eiji, Toshiyuki Tanaka, Hidenobu Kanda, et al. "Nepmucin, a novel HEV sialomucin, mediates L-selectin–dependent lymphocyte rolling and promotes lymphocyte adhesion under flow." Journal of Experimental Medicine 203, no. 6 (2006): 1603–14. http://dx.doi.org/10.1084/jem.20052543.

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Lymphocyte trafficking to lymph nodes (LNs) is initiated by the interaction between lymphocyte L-selectin and certain sialomucins, collectively termed peripheral node addressin (PNAd), carrying specific carbohydrates expressed by LN high endothelial venules (HEVs). Here, we identified a novel HEV-associated sialomucin, nepmucin (mucin not expressed in Peyer's patches [PPs]), that is expressed in LN HEVs but not detectable in PP HEVs at the protein level. Unlike conventional sialomucins, nepmucin contains a single V-type immunoglobulin (Ig) domain and a mucin-like domain. Using materials affini

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Baekkevold, Espen S., Takeshi Yamanaka, Roger T. Palframan, et al. "The Ccr7 Ligand ELC (Ccl19) Is Transcytosed in High Endothelial Venules and Mediates T Cell Recruitment." Journal of Experimental Medicine 193, no. 9 (2001): 1105–12. http://dx.doi.org/10.1084/jem.193.9.1105.

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Lymphocyte homing to secondary lymphoid tissue is defined by a multistep sequence of interactions between lymphocytes and endothelial cells in high endothelial venules (HEVs). After initial selectin-mediated tethering and rolling, firm adhesion of lymphocytes requires rapid upregulation of lymphocyte integrin adhesiveness. This step is mediated in part by the HEV-derived chemokine SLC (secondary lymphoid-tissue chemokine, or CCL21) that binds to the CC chemokine receptor (CCR)7 on lymphocytes. However, the CC chemokine ELC (Epstein-Barr virus–induced molecule 1 ligand chemokine, or CCL19) shar

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Shen, Caiying, Peng Shan, and Tao Gao. "A Comprehensive Overview of Hybrid Electric Vehicles." International Journal of Vehicular Technology 2011 (November 24, 2011): 1–7. http://dx.doi.org/10.1155/2011/571683.

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As the environmental pollution and energy crises are getting more and more remarkable, hybrid electric vehicles (HEVs) have taken on an accelerated pace in the world. A comprehensive overview of HEVs is presented in this paper, with the emphasis on configurations, main issues, and energy management strategies. Conclusions are discussed finally.

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Heintzel, Alexander. "Boosting HEVs and BEVs." ATZelectronics worldwide 16, no. 5 (2021): 6–7. http://dx.doi.org/10.1007/s38314-021-0634-7.

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Sharma, Rashmi, Rahul Sharma, and Minakshi Kaushik. "Fuel Economy Optimisation by Utilising Hybrid Energy Storage Systems." Journal of Futuristic Sciences and Applications 1, no. 1 (2018): 12–16. http://dx.doi.org/10.51976/jfsa.111803.

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The onboard energy-storage system (ESS) of hybrid electric vehicles (HEVs) has a significant impact on their fuel efficiency and all-electric range (AER). Energy-storage Devices charge when there is little demand for electricity and discharge when high power requirements that operate as catalysts to boost energy. In ground vehicles, batteries serve as the main energy storage mechanism. Vehicles with an AER of 15% or more almost twice the added expense of the ESS. As the result ESS requires more peak power while maintaining high energy density of HEVs. In comparison to batteries, ultracapacitor

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Zhang, Qi, Yunlong Shang, Yan Li, and Rui Zhu. "A Concise Review of Power Batteries and Battery Management Systems for Electric and Hybrid Vehicles." Energies 18, no. 14 (2025): 3750. https://doi.org/10.3390/en18143750.

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The core powertrain components of electric vehicles (EVs) and hybrid electric vehicles (HEVs) are the power batteries and battery management system (BMS), jointly determining the performance, safety, and economy of the vehicle. This review offers a comprehensive overview of the evolution and current advancements in power battery and BMS technology for electric vehicles (EVs). It emphasizes product upgrades and replacements while also analyzing future research hotspots and development trends driven by the increasing demand for EVs and hybrid electric vehicles (HEVs). This review aims to give re

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Warnock, R. A., J. J. Campbell, M. E. Dorf, A. Matsuzawa, L. M. McEvoy, and E. C. Butcher. "The Role of Chemokines in the Microenvironmental Control of T versus B Cell Arrest in Peyer's Patch High Endothelial Venules." Journal of Experimental Medicine 191, no. 1 (2000): 77–88. http://dx.doi.org/10.1084/jem.191.1.77.

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Chemokines have been hypothesized to contribute to the selectivity of lymphocyte trafficking not only as chemoattractants, but also by triggering integrin-dependent sticking (arrest) of circulating lymphocytes at venular sites of extravasation. We show that T cells roll on most Peyer's patch high endothelial venules (PP-HEVs), but preferentially arrest in segments displaying high levels of luminal secondary lymphoid tissue chemokine (SLC) (6Ckine, Exodus-2, thymus-derived chemotactic agent 4 [TCA-4]). This arrest is selectively inhibited by functional deletion (desensitization) of CC chemokine

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Ginzarly, Riham, Nazih Moubayed, Ghaleb Hoblos, Hassan Kanj, Mouhammad Alakkoumi, and Alaa Mawas. "Assessing HMM and SVM for Condition-Based Monitoring and Fault Detection in HEV Electrical Machines." Energies 18, no. 13 (2025): 3513. https://doi.org/10.3390/en18133513.

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The rise of hybrid electric vehicles (HEVs) marks a shift away from traditional engines driven by environmental and economic concerns. With the rapid growth of HEVs worldwide, their reliability becomes of utmost concern; thus, guaranteeing the proper operation of HEVs is a crucial quest. Condition-based monitoring (CBM), which intends to observe different kinds of parameters in the system to detect defects and reduce any unwanted breakdowns and equipment failure, plays an efficient role in enhancing HEVs’ reliability and ensuring their healthy operation. The permanent magnet machine (PMM) is t

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Chen, Ding Yue, Li Feng Wang, Li Hao Chen, Yu Sun, and Jian Chao Bao. "The Design Method of Extended Range Electric Vehicles." Advanced Materials Research 827 (October 2013): 61–65. http://dx.doi.org/10.4028/www.scientific.net/amr.827.61.

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The energy and the environment are two main factors restraining the development of automobile industry. Besides its high feasibility, hybrid electric vehicles (HEVs) also holds the advantages concerning with energy and environment. This article will discuss on the work mode and specific design scheme of the extended range electric vehicles (EREVs), one of HEVs most important research direction.

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van Zante, A., and S. D. Rosen. "Sulphated endothelial ligands for L-selectin in lymphocyte homing and inflammation." Biochemical Society Transactions 31, no. 2 (2003): 313–17. http://dx.doi.org/10.1042/bst0310313.

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Lymphocytes from the blood home to secondary lymphoid tissues through a process of tethering, rolling, firm adhesion and transmigration. Tethering and rolling of lymphocytes is mediated by the interaction of L-selectin on lymphocytes with sulphated ligands expressed by the specialized endothelial cells of high endothelial venules (HEVs). The sulphate-dependent monoclonal antibody MECA79 stains HEVs in peripheral lymph nodes and recognizes the complex of HEV ligands for L-selectin termed peripheral node addressin. High endothelial cell GlcNAc-6-sulphotransferase/L-selectin ligand sulphotransfer

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Mustapa, Siti Indati, Bamidele Victor Ayodele, Waznatol Widad Mohamad Ishak, and Freida Ozavize Ayodele. "Evaluation of Cost Competitiveness of Electric Vehicles in Malaysia Using Life Cycle Cost Analysis Approach." Sustainability 12, no. 13 (2020): 5303. http://dx.doi.org/10.3390/su12135303.

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The need to mitigate CO2 emissions from the transportation sector has necessitated the adoption of electric vehicles (EVs) and other forms of alternative vehicles. Despite the global rise of EVs demand as a complementary means of green transportations, the level of adoption in Malaysia is still not encouraging. Therefore, this study aimed to investigate the cost competitiveness of EVs in comparison with Hybrid Electric Vehicles (HEVs) and an Internal Combustion Vehicle (ICV) based on Malaysia scenarios. Using the existing data in Malaysia, life cost analysis (LCC) of two EVs was computed and c

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Essa, Mohamed El-Sayed M., Joseph Victor W. Lotfy, M. Essam K. Abd-Elwahed, Khaled Rabie, Basem M. ElHalawany, and Mahmoud Elsisi. "Low-Cost Hardware in the Loop for Intelligent Neural Predictive Control of Hybrid Electric Vehicle." Electronics 12, no. 4 (2023): 971. http://dx.doi.org/10.3390/electronics12040971.

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The design and investigation of an intelligent controller for hardware-in-the-loop (HIL) implementation of hybrid electric vehicles (HEVs) are proposed in this article. The proposed intelligent controller is adopted based on the enhancement of a model predictive controller (MPC) by an artificial neural network (ANN) approach. The MPC-based ANN (NNMPC) is proposed to control the speed of HEVs for a simulation system model and experimental HIL test systems. The HIL is established to assess the performance of the NNMPC to control the velocity of HEVs in an experimental environment. The real-time

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Shi, Dapai, Jiaheng Wang, Kangjie Liu, Chengwei Sun, Zhenghong Wang, and Xiaoqing Liu. "Techno-Economic Analysis of Hydrogen Hybrid Vehicles." World Electric Vehicle Journal 16, no. 8 (2025): 418. https://doi.org/10.3390/wevj16080418.

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Driven by carbon neutrality and peak carbon policies, hydrogen energy, due to its zero-emission and renewable properties, is increasingly being used in hydrogen fuel cell vehicles (H-FCVs). However, the high cost and limited durability of H-FCVs hinder large-scale deployment. Hydrogen internal combustion engine hybrid electric vehicles (H-HEVs) are emerging as a viable alternative. Research on the techno-economics of H-HEVs remains limited, particularly in systematic comparisons with H-FCVs. This paper provides a comprehensive comparison of H-FCVs and H-HEVs in terms of total cost of ownership

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Faveeuw, Christelle, Graham Preece, and Ann Ager. "Transendothelial migration of lymphocytes across high endothelial venules into lymph nodes is affected by metalloproteinases." Blood 98, no. 3 (2001): 688–95. http://dx.doi.org/10.1182/blood.v98.3.688.

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Abstract The migration of lymphocytes from the bloodstream into lymph nodes (LNs) via high endothelial venules (HEVs) is a prerequisite for the detection of processed antigen on mature dendritic cells and the initiation of immune responses. The capture and arrest of lymphocytes from flowing blood is mediated by the multistep adhesion cascade, but the mechanisms that lymphocytes use to penetrate the endothelial lining and the basement membrane of HEVs are poorly understood. Matrix metalloproteinases (MMPs) control the metastatic spread of tumor cells by regulating the penetration blood vessel b

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Bekkhus, Tove, Teemu Martikainen, Anna Olofsson, et al. "Remodeling of the Lymph Node High Endothelial Venules Reflects Tumor Invasiveness in Breast Cancer and is Associated with Dysregulation of Perivascular Stromal Cells." Cancers 13, no. 2 (2021): 211. http://dx.doi.org/10.3390/cancers13020211.

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The tumor-draining lymph nodes (TDLNs) are primary sites for induction of tumor immunity. They are also common sites of metastasis, suggesting that tumor-induced mechanisms can subvert anti-tumor immune responses and promote metastatic seeding. The high endothelial venules (HEVs) together with CCL21-expressing fibroblastic reticular cells (FRCs) are essential for lymphocyte recruitment into the LNs. We established multicolor antibody panels for evaluation of HEVs and FRCs in TDLNs from breast cancer (BC) patients. Our data show that patients with invasive BC display extensive structural and mo

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Bekkhus, Tove, Teemu Martikainen, Anna Olofsson, et al. "Remodeling of the Lymph Node High Endothelial Venules Reflects Tumor Invasiveness in Breast Cancer and is Associated with Dysregulation of Perivascular Stromal Cells." Cancers 13, no. 2 (2021): 211. http://dx.doi.org/10.3390/cancers13020211.

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The tumor-draining lymph nodes (TDLNs) are primary sites for induction of tumor immunity. They are also common sites of metastasis, suggesting that tumor-induced mechanisms can subvert anti-tumor immune responses and promote metastatic seeding. The high endothelial venules (HEVs) together with CCL21-expressing fibroblastic reticular cells (FRCs) are essential for lymphocyte recruitment into the LNs. We established multicolor antibody panels for evaluation of HEVs and FRCs in TDLNs from breast cancer (BC) patients. Our data show that patients with invasive BC display extensive structural and mo

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Torreglosa, Juan P., Pablo Garcia-Triviño, David Vera, and Diego A. López-García. "Analyzing the Improvements of Energy Management Systems for Hybrid Electric Vehicles Using a Systematic Literature Review: How Far Are These Controls from Rule-Based Controls Used in Commercial Vehicles?" Applied Sciences 10, no. 23 (2020): 8744. http://dx.doi.org/10.3390/app10238744.

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The hybridization of vehicles is a viable step toward overcoming the challenge of the reduction of emissions related to road transport all over the world. To take advantage of the emission reduction potential of hybrid electric vehicles (HEVs), the appropriate design of their energy management systems (EMSs) to control the power flow between the engine and the battery is essential. This work presents a systematic literature review (SLR) of the more recent works that developed EMSs for HEVs. The review is carried out subject to the following idea: although the development of novel EMSs that see

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Mittal, Vikram, and Rajesh Shah. "Energy Management Strategies for Hybrid Electric Vehicles: A Technology Roadmap." World Electric Vehicle Journal 15, no. 9 (2024): 424. http://dx.doi.org/10.3390/wevj15090424.

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Hybrid electric vehicles (HEVs) are set to play a critical role in the future of the automotive industry. To operate efficiently, HEVs require a robust energy management strategy (EMS) that decides whether the vehicle is powered by the engine or electric motors while managing the battery’s state of charge. The EMS must rapidly adapt to driver demands and optimize energy usage, ideally predicting battery charge rates and fuel consumption to adjust the powertrain in real time, even under unpredictable driving conditions. As HEVs become more prevalent, EMS technologies will advance to improve pre

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Nagendar, Kavati, and V. Vijaya Rama Raju. "ANN Based Current Controller for Hybrid Electric Vehicles." E3S Web of Conferences 309 (2021): 01065. http://dx.doi.org/10.1051/e3sconf/202130901065.

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The use of Hybrid Electric Vehicles (HEVs) across the world is growing enormously every day. The single-phase bi-directional convertors are presented in this study for HEVs on-board charging(OBC). In HEVs, we use power electronics converters for the converting and inverting operations. Artificial Neural Network(ANN) is presented in this study for simple operation and high optimization approaches. ANN control technique regulates the system's THD and enhances charging system optimization, enables two-way power delivery that is from the grid to vehicle and the vehicle to grid. An ANN based curren

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