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Relevant bibliographies by topics / Hexadentate chelation

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Journal articles
Dissertations / Theses
Conference papers

Academic literature on the topic 'Hexadentate chelation'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Hexadentate chelation"

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Melendez-Zamudio, Miguel, Kevina Chavda, and Michael A. Brook. "Chelating Silicone Dendrons: Trying to Impact Organisms by Disrupting Ions at Interfaces." Molecules 27, no. 6 (2022): 1869. http://dx.doi.org/10.3390/molecules27061869.

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The viability of pathogens at interfaces can be disrupted by the presence of (cationic) charge and chelating groups. We report on the synthesis of silicone dendrimers and linear polymers based on a motif of hexadentate ligands with the ability to capture and deliver metal ions. Mono-, di- or trialkoxysilanes are converted in G1 to analogous vinylsilicones and then, iteratively using the Piers-Rubinsztajn reaction and hydrosilylation, each vinyl group is transformed into a trivinyl cluster at G2. The thiol-ene reaction with cysteamine or 3-mercaptopropionic acid and the trivinyl cluster leads t

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Zhou, Tao, Robert C. Hider, and Xiaole Kong. "Mode of iron(iii) chelation by hexadentate hydroxypyridinones." Chemical Communications 51, no. 26 (2015): 5614–17. http://dx.doi.org/10.1039/c4cc10339d.

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Tripodal hexadentate hydroxypyridin-4-ones are increasingly utilised as iron(iii) and gallium(iii) ligands, their attachment to proteins being particularly useful for positron emission tomography (PET). A tripodal ligand NTA(BuHP)<sub>3</sub>, which is reported to form 1 : 1 iron(iii) and gallium(iii) complexes in aqueous, media forms 2 : 2 complexes under physiological conditions.

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Zhou, Tao, Xiao-Le Kong, and Robert C. Hider. "Synthesis and iron chelating properties of hydroxypyridinone and hydroxypyranone hexadentate ligands." Dalton Transactions 48, no. 10 (2019): 3459–66. http://dx.doi.org/10.1039/c8dt05014g.

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Devanur, Lakshmi D., Robert W. Evans, Patricia J. Evans, and Robert C. Hider. "Chelator-facilitated removal of iron from transferrin: relevance to combined chelation therapy." Biochemical Journal 409, no. 2 (2007): 439–47. http://dx.doi.org/10.1042/bj20070823.

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Current iron chelation therapy consists primarily of DFO (desferrioxamine), which has to be administered via intravenous infusion, together with deferiprone and deferasirox, which are orally-active chelators. These chelators, although effective at decreasing the iron load, are associated with a number of side effects. Grady suggested that the combined administration of a smaller bidentate chelator and a larger hexadentate chelator, such as DFO, would result in greater iron removal than either chelator alone [Grady, Bardoukas and Giardina (1998) Blood 92, 16b]. This in turn could lead to a decr

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Pramanik, Kausikisankar, Soma Karmakar, Suranjan Bhanja Choudhury, and Animesh Chakravorty. "Thioether-Coordinated Nickel Oxidation States. A NiIIIS2N4Family Incorporating Hexadentate Thioether−Azo−Oxime Chelation." Inorganic Chemistry 36, no. 16 (1997): 3562–64. http://dx.doi.org/10.1021/ic970009a.

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Porter, J., C. Borgna-Pignatti, M. Baccarani, et al. "Iron Chelation Efficiency of Deferasirox (Exjade®, ICL670) in Patients with Transfusional Hemosiderosis." Blood 106, no. 11 (2005): 2690. http://dx.doi.org/10.1182/blood.v106.11.2690.2690.

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Abstract Iron excretion can be calculated according to Angelucci et al (NEJM 2000). As applied to the novel oral iron chelator deferasirox (DSX), chelation efficiency can then be determined as the % iron excretion vs theoretical iron binding capacity of chelator dose: % efficiency = [iron excretion (mg/kg/day)/chelator dose (mg/kg/day)] x [374/56] x 2 x 100 (374 and 56 represent the molecular weights of DSX and iron; factor 2 accounts for the tridentate ligand). In a total of 325 patients with β-thalassemia (n=285) or rare anemias, such as MDS (n=13), DBA (n=14) or other anemias (n=13), includ

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Szigethy, Géza, and Kenneth N. Raymond. "Hexadentate Terephthalamide(bis-hydroxypyridinone) Ligands for Uranyl Chelation: Structural and Thermodynamic Consequences of Ligand Variation(1)." Journal of the American Chemical Society 133, no. 20 (2011): 7942–56. http://dx.doi.org/10.1021/ja201511u.

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Maclean, Kirsteen H., John L. Cleveland, and John B. Porter. "Cellular zinc content is a major determinant of iron chelator–induced apoptosis of thymocytes." Blood 98, no. 13 (2001): 3831–39. http://dx.doi.org/10.1182/blood.v98.13.3831.

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Abstract Desferrioxamine (DFO) and the hydroxypiridinone (HPO) deferiprone (CP20) chelate iron as well as other metals. These chelators are used clinically to treat iron overload, but they induce apoptosis in thymocytes. Thymocyte apoptosis is potentiated by zinc deficiency, suggesting that these iron chelators may induce apoptosis by depleting stores of zinc. Exposure of murine thymocytes to either DFO or deferiprone resulted in significant reductions in the labile intracellular zinc pool. Moreover, increasing intracellular zinc levels, by chronic zinc dietary supplementation to mice or in vi

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9

Link, G., A. Pinson, and C. Hershko. "Ability of the orally effective iron chelators dimethyl- and diethyl- hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells." Blood 83, no. 9 (1994): 2692–97. http://dx.doi.org/10.1182/blood.v83.9.2692.2692.

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Abstract In view of the profound functional and structural abnormalities shown in our previous studies in cultured, iron-loaded rat heart cells, we have examined the ability of the orally effective iron chelators dimethyl-3-hydroxypyrid-4-one (DMHP or L1) and diethyl-3-hydroxy-pyrid- 4-one (DEHP or CP94) and of deferoxamine (DF) to reverse the damage caused by iron loading to heart cell organelles. At a concentration of 1.0 mmol/L, all three iron chelators were equally efficient in removing iron and restoring the activity of the thiolic sarcolemmal enzymes 5′- nucleotidase and Na,K,ATPase. How

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Link, G., A. Pinson, and C. Hershko. "Ability of the orally effective iron chelators dimethyl- and diethyl- hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells." Blood 83, no. 9 (1994): 2692–97. http://dx.doi.org/10.1182/blood.v83.9.2692.bloodjournal8392692.

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In view of the profound functional and structural abnormalities shown in our previous studies in cultured, iron-loaded rat heart cells, we have examined the ability of the orally effective iron chelators dimethyl-3-hydroxypyrid-4-one (DMHP or L1) and diethyl-3-hydroxy-pyrid- 4-one (DEHP or CP94) and of deferoxamine (DF) to reverse the damage caused by iron loading to heart cell organelles. At a concentration of 1.0 mmol/L, all three iron chelators were equally efficient in removing iron and restoring the activity of the thiolic sarcolemmal enzymes 5′- nucleotidase and Na,K,ATPase. However, at

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Dissertations / Theses on the topic "Hexadentate chelation"

1

Tilbrook, Gary Stuart. "Design and synthesis of hexadentate iron (III) chelating agents." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294858.

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Conference papers on the topic "Hexadentate chelation"

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Haraga, Tomoko, Yuta Nakano, Masami Shibukawa, Yutaka Kameo, Kuniaki Takahashi, and Shingo Saito. "Capillary Electrophoresis With Laser-Induced Fluorescent Detection Method Using Highly Emissive Probes for Analysis of Actinides in Radioactive Wastes." In ASME 2011 14th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2011. http://dx.doi.org/10.1115/icem2011-59092.

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Actinides are important nuclides for the analysis of radioactive wastes arising from nuclear fuel cycle facilities. In order to achieve simple and rapid analysis of actinides, capillary electrophoresis-laser-induced fluorescent detection method (CE-LIF) is one of the potential candidates. In this study, new emissive probes of actinide ions suitable for CE-LIF were developed for the first time. The detection and separation of americium and neptunium ions as model nuclides were examined using several new emissive complexing probes, each of which possessed a fluorophore and a different chelating

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