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1

Hammoud, Rola, Emanuela Pannia, Chih-Sheng Liao, et al. "Choline Supplementation Mitigates the Adverse Effects of a High Folic Acid Maternal Diet on Food Intake Regulation in the Offspring." Current Developments in Nutrition 4, Supplement_2 (2020): 1806. http://dx.doi.org/10.1093/cdn/nzaa067_033.

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Abstract Objectives Folic acid (FA) intake by many women in North America is exceeding recommendations. We have shown that high maternal FA induces methylation-dependent programming of energy regulation associated with an obesogenic phenotype in adult rat offspring. However, it is unclear if this is a direct effect of high FA or due to an imbalance between FA and other methyl-nutrients (i.e., choline) in the 1-carbon cycle. Unlike FA, choline intake by women is below recommendations and is absent from most prenatal supplements, potentially affecting fetal development. The objective of this stu
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Hopkins, Mark, Catherine Gibbons, Phillipa Caudwell, John E. Blundell, and Graham Finlayson. "Differing effects of high-fat or high-carbohydrate meals on food hedonics in overweight and obese individuals." British Journal of Nutrition 115, no. 10 (2016): 1875–84. http://dx.doi.org/10.1017/s0007114516000775.

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AbstractAlthough the effects of dietary fat and carbohydrate on satiety are well documented, little is known about the impact of these macronutrients on food hedonics. We examined the effects ofad libitumand isoenergetic meals varying in fat and carbohydrate on satiety, energy intake and food hedonics. In all, sixty-five overweight and obese individuals (BMI=30·9 (sd3·8) kg/m2) completed two separate test meal days in a randomised order in which they consumed high-fat/low-carbohydrate (HFLC) or low-fat/high-carbohydrate (LFHC) foods. Satiety was measured using subjective appetite ratings to ca
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Raharjo, Budiono, and Solichul Hadi. "HIGH FLUORESCENT LYMPHOCYTE COUNT EXAMINATION IN DENGUE HEMORRHAGIC PATIENTS WITH SYSMEX XN-1000 HEMATOLOGY ANALYZER." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 25, no. 2 (2019): 207. http://dx.doi.org/10.24293/ijcpml.v25i2.1443.

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Sysmex XN-1000 hematology analyzer is an automated 5-part diff analyzer (eosinophils, basophils, neutrophils, lymphocytes, and monocytes). In the calculated area, the type of difference between the Sysmex hematology device and other hematology devices is Immature Granulocyte (IG), Nucleated Red Blood Cell (NRBC), and High Fluorescent Lymphocytes Count (HFLC). The cells calculated in the HFLC area are atypical lymphocytes. In patients with dengue hemorrhagic fever, it is often found atypical lymphocytes called blue plasma lymphocytes. The purpose of this study was to determine the description o
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Bandyopadhyay, Kaustav, Pabitra Kumar Parua, Ajit Bikram Datta та Pradeep Parrack. "Escherichia coli HflK and HflC can individually inhibit the HflB (FtsH)-mediated proteolysis of λCII in vitro". Archives of Biochemistry and Biophysics 501, № 2 (2010): 239–43. http://dx.doi.org/10.1016/j.abb.2010.06.030.

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5

Hafez, Ahmed T., and Mohamed A. Kamel. "Cooperative Task Assignment and Trajectory Planning of Unmanned Systems Via HFLC and PSO." Unmanned Systems 07, no. 02 (2019): 65–81. http://dx.doi.org/10.1142/s2301385019500018.

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This paper investigates the problems of cooperative task assignment and trajectory planning for teams of cooperative unmanned aerial vehicles (UAVs). A novel approach of hierarchical fuzzy logic controller (HFLC) and particle swarm optimization (PSO) is proposed. Initially, teams of UAVs are moving in a pre-defined formation covering a specified area. When one or more targets are detected, the teams send a package of information to the ground station (GS) including the target’s degree of threat, degree of importance, and the separating distance between each team and each detected target. Based
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Haider, Rana Zeeshan, Najeed Ahmed Khan, Eloisa Urrechaga, and Tahir Sultan Shamsi. "Mature and Immature/Activated Cells Fractionation: Time for a Paradigm Shift in Differential Leucocyte Count Reporting?" Diagnostics 11, no. 6 (2021): 922. http://dx.doi.org/10.3390/diagnostics11060922.

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Leucocytes, especially neutrophils featuring pro- and anti-cancerous characteristics, are involved in nearly every stage of tumorigenesis. Phenotypic and functional differences among mature and immature neutrophil fractions are well reported, and their correlation with tumor progression and therapy has emerging implications in modern oncology practices. Technological advancements enabled modern hematology analyzers to generate extended information (research parameters) during complete blood cell count (CBC) analysis. We hypothesized that neutrophil and lymphocyte fractions-related extended dif
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7

Breda, Laura, Sara Gardenghi, Ella Guy, et al. "Kinetic of Iron Absorption and Expression of Iron Related Genes in Beta-Thalassemia." Blood 106, no. 11 (2005): 3846. http://dx.doi.org/10.1182/blood.v106.11.3846.3846.

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Abstract We generated the first transplantable adult mouse models of beta-thalassemia intermedia and major by infusing mouse hematopoietic-fetal-liver cells (HFLC) heterozygous or homozygous for a deletion of the beta-globin gene (respectively with th3/+ and th3/th3 cells) into lethally irradiated congenic C57BL/6 mice. Six to 8 weeks post transplantation, mice transplanted with th3/+ HFLCs show 7 to 9 g/dL of hemoglobin levels, splenomegaly, abnormal red cells and increased iron overload. Mice transplanted with th3/th3 HFLCs, unless blood transfused, die 8 to 10 weeks after engraftment showin
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Dutta, Dipak, Kaustav Bandyopadhyay, Ajit Bikram Datta, Abhijit A. Sardesai, and Pradeep Parrack. "Properties of HflX, an Enigmatic Protein from Escherichia coli." Journal of Bacteriology 191, no. 7 (2009): 2307–14. http://dx.doi.org/10.1128/jb.01353-08.

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ABSTRACT The Escherichia coli gene hflX was first identified as part of the hflA operon, mutations in which led to an increased frequency of lysogenization upon infection of the bacterium by the temperate coliphage lambda. Independent mutational studies have also indicated that the HflX protein has a role in transposition. Based on the sequence of its gene, HflX is predicted to be a GTP-binding protein, very likely a GTPase. We report here purification and characterization of the HflX protein. We also specifically examined its suggested functional roles mentioned above. Our results show that H
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9

Chavero-Navarrete, Ernesto, Mario Trejo-Perea, Juan Carlos Jáuregui-Correa, Roberto Valentín Carrillo-Serrano, Guillermo Ronquillo-Lomeli, and José Gabriel Ríos-Moreno. "Hierarchical Pitch Control for Small Wind Turbines Based on Fuzzy Logic and Anticipated Wind Speed Measurement." Applied Sciences 10, no. 13 (2020): 4592. http://dx.doi.org/10.3390/app10134592.

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Bringing electricity to areas of difficult terrain is a complicated task, so it is convenient to generate power using local natural resources, such as wind, through a small horizontal-axis wind turbine (S-HAWT). However, at the rotor height of these wind turbines, the wind is often turbulent due to obstacles such as trees and buildings. For a turbine to function properly in these conditions, the action of the wind force on the rotor must be smoothed out by controlling the pitch angle. A commercial derivative-integral-proportional (PID)-type pitch controller works well when system dynamics are
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10

Kihara, A., Y. Akiyama, and K. Ito. "Host regulation of lysogenic decision in bacteriophage : Transmembrane modulation of FtsH (HflB), the cII degrading protease, by HflKC (HflA)." Proceedings of the National Academy of Sciences 94, no. 11 (1997): 5544–49. http://dx.doi.org/10.1073/pnas.94.11.5544.

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11

Barros, Érico Luiz Damasceno, Shelon Cristina Souza Pinto, Alvaro Henrique Borges, et al. "Toothpaste Prevents Debonded Brackets on Erosive Enamel." Scientific World Journal 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/468582.

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This study evaluated the effect of high fluoride dentifrice on the bond strength of brackets after erosive challenge. Eighty-four enamel specimens were divided into seven groups(n=12): WN (distilled water/no acid challenge), W3C (distilled water/3 cycles of acid challenge), and W6C (distilled water/6 cycles of acid challenge) were not submitted to dentifrice treatment. Groups RF3C (regular fluoride dentifrice/3 cycles of acid challenge) and RF6C (regular fluoride dentifrice/6 cycles of acid challenge) were treated with dentifrices containing 1450 μg F−/g and HF3C (high fluoride dentifrice/3 cy
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Kihara, A., Y. Akiyama, and K. Ito. "A protease complex in the Escherichia coli plasma membrane: HflKC (HflA) forms a complex with FtsH (HflB), regulating its proteolytic activity against SecY." EMBO Journal 15, no. 22 (1996): 6122–31. http://dx.doi.org/10.1002/j.1460-2075.1996.tb01000.x.

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Gou, Xunjie, Zeshui Xu, and Huchang Liao. "Hesitant Fuzzy Linguistic Possibility Degree-Based Linear Assignment Method for Multiple Criteria Decision-Making." International Journal of Information Technology & Decision Making 18, no. 01 (2019): 35–63. http://dx.doi.org/10.1142/s0219622017500377.

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Hesitant fuzzy linguistic term set (HFLTS), as a flexible tool to represent people’s uncertain cognition, has attracted lots of scholars’ research interests, and a series of methodologies have been proposed to deal with a variety of decision-making problems. In this paper, we develop a hesitant fuzzy linguistic possibility degree-based linear assignment (HFL-PDLA) method to tackle the multiple criteria decision-making (MCDM) problems under hesitant fuzzy linguistic environment. Firstly, we define the possibility degree of hesitant fuzzy linguistic element (HFLE). Additionally, some relevant co
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14

Ma, Weimin, Wenjing Lei, and Bingzhen Sun. "Three-way group decisions under hesitant fuzzy linguistic environment for green supplier selection." Kybernetes 49, no. 12 (2020): 2919–45. http://dx.doi.org/10.1108/k-09-2019-0602.

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Purpose The purpose of this paper is to propose a three-way group decision-making approach to address the selection of green supplier, by extending decision-theoretic rough set (DTRS) into hesitant fuzzy linguistic (HFL) environment, considering the flexible evaluation expression format of HFL term set (HFLTS) and the idea of minimum expected risk in DTRS. Design/methodology/approach Specifically, the authors first present the calculation method of the conditional probability and discuss the loss functions of DTRS with HFL element (HFLE), along with some associated properties being investigate
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Park, Man-Young, Jong-Hoon Son, Sang-Woo Kang, and Shi-Woo Rhee. "Comparison of (hexafluoroacetylacetonate)Cu(vinyltrimethylsilane) and (hexafluoroacetylacetonate)Cu(allyltrimethylsilane) for metalorganic chemical vapor deposition of copper." Journal of Materials Research 14, no. 3 (1999): 975–79. http://dx.doi.org/10.1557/jmr.1999.0129.

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For the metalorganic chemical vapor deposition (MOCVD) of copper, (hfac)Cu(VTMS) (hfac = hexafluoroacetylacetonate, VTMS = vinyltrimethylsilane) and (hfac)Cu(ATMS) (ATMS = allyltrimethylsilane) were compared, and the effect of L ligand in (hfac)Cu–L was examined. It was found by 1H-NMR (nuclear magnetic resonance) that the thermal stability of (hfac)Cu(VTMS) was better than that of (hfac)Cu(ATMS) due to the relatively weak Cu–ATMS bond. From in situ Fourier transform infrared spectroscopy (FTIR) experiments, the formation of Cu(hfac)2, the product of disproportion reaction of Cu(hfac), was obs
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Dai, Yujie, Jingjing Ding, Wen Yin, et al. "Increased Autophagy Enhances the Resistance to Tumor Necrosis Factor-Alpha Treatment in Rheumatoid Arthritis Human Fibroblast-Like Synovial Cell." BioMed Research International 2018 (October 25, 2018): 1–9. http://dx.doi.org/10.1155/2018/4941027.

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Tumor Necrosis Factor-alpha (TNF-α) was reported to increase autophagy in rheumatoid arthritis human fibroblast-like synovial cell (RA-HFLS). We investigated different levels of TNF-α exposed to RA-HFLS by focusing on the relationship of autophagy and apoptosis. RA-HFLS and normal human fibroblast-like synovial cell (HFLS) were stimulated by TNF-α in the presence or the absence of 3-methyladenine (3-MA) or chloroquine (CQ). Cell apoptosis was detected by flow cytometry. Autophagy was determined through the expression levels of LC3, Beclin1, and P62 measured by Western Blot analysis as well as
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17

Koyauchi, Takafumi, Hideki Yasui, Noriyuki Enomoto, et al. "Pulse oximetric saturation to fraction of inspired oxygen (SpO2/FIO2) ratio 24 hours after high-flow nasal cannula (HFNC) initiation is a good predictor of HFNC therapy in patients with acute exacerbation of interstitial lung disease." Therapeutic Advances in Respiratory Disease 14 (January 2020): 175346662090632. http://dx.doi.org/10.1177/1753466620906327.

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Background: High-flow nasal cannula (HFNC) oxygen therapy provides effective respiratory management in patients with hypoxemic respiratory failure. However, the efficacy and tolerability of HFNC for patients with acute exacerbation of interstitial lung disease (AE-ILD) have not been established. This study was performed to assess the efficacy and tolerability of HFNC for patients with AE-ILD and identify the early predictors of the outcome of HFNC treatment. Methods: We retrospectively reviewed the records of patients with AE-ILD who underwent HFNC. Overall survival, the success rate of HFNC t
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Lethesh, Kallidanthiyil Chellappan, Sigurd Øien-Ødegaard, Kaushik Jayasayee, and Anne Fiksdahl. "Synthesis of magnesium complexes of ionic liquids with highly coordinating anions." Dalton Transactions 48, no. 3 (2019): 982–88. http://dx.doi.org/10.1039/c8dt04364g.

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Magnesium-complexes [Mg<sup>2+</sup>(hfac<sup>−</sup>)<sub>3</sub>][Cation<sup>+</sup>] were prepared from Mg(Tf<sub>2</sub>N)<sub>2</sub>and ILs; [C<sub>4</sub>mim][hfac], [C<sub>4</sub>Pyr][hfac], [C<sub>4</sub>Pip][hfac], [C<sub>6</sub>Morph][hfac], and [C<sub>4</sub>Pyrr][hfac]; complex-characterization by<sup>1</sup>H and<sup>13</sup>C NMR, and X-ray spectroscopy.
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Delbove, Agathe, Ambroise Foubert, François Mateos, Tiphaine Guy, and Marie Gousseff. "High flow nasal cannula oxygenation in COVID-19 related acute respiratory distress syndrome: a safe way to avoid endotracheal intubation?" Therapeutic Advances in Respiratory Disease 15 (January 2021): 175346662110195. http://dx.doi.org/10.1177/17534666211019555.

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Backgrounds: High flow nasal cannula (HFNC) is an alternative therapy for acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19). This study aimed first to describe outcomes of patients suffering from COVID-19-related ARDS treated with HFNC; secondly to evaluate safety of HFNC (patients and healthcare workers) and compare patients according to respiratory outcome. Methods: A retrospective cohort was conducted in French general hospital intensive care unit (ICU). Patients were included if receiving HFNC for hypoxemia (saturation pulse oxygen (SpO2) &lt;92% under o
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Kansal, Amit, Shekhar Dhanvijay, Andrew Li, et al. "Predictors and outcomes of high-flow nasal cannula failure following extubation: A multicentre observational study." Annals of the Academy of Medicine, Singapore 50, no. 6 (2021): 467–73. http://dx.doi.org/10.47102/annals-acadmedsg.2020564.

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Introduction: Despite adhering to criteria for extubation, up to 20% of intensive care patients require re-intubation, even with use of post-extubation high-flow nasal cannula (HFNC). This study aims to identify independent predictors and outcomes of extubation failure in patients who failed postextubation HFNC. Methods: We conducted a multicentre observational study involving 9 adult intensive care units (ICUs) across 5 public hospitals in Singapore. We included patients extubated to HFNC following spontaneous breathing trials. We compared patients who were successfully weaned off HFNC with t
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Storgaard, Line Hust, Hans-Ulrich Hockey, and Ulla Møller Weinreich. "Development in PaCO2 over 12 months in patients with COPD with persistent hypercapnic respiratory failure treated with high-flow nasal cannula—post-hoc analysis from a randomised controlled trial." BMJ Open Respiratory Research 7, no. 1 (2020): e000712. http://dx.doi.org/10.1136/bmjresp-2020-000712.

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IntroductionPersistent hypercapnic failure in chronic obstructive pulmonary disease (COPD) is associated with poor prognosis. Long-term home non-invasive ventilation is recommended for patients with PaCO2 &gt;7.0 kPa. Domiciliary high-flow nasal cannula (HFNC) reduces PaCO2 in short-term studies. This post-hoc analysis examines the effect of HFNC on PaCO2 levels, exacerbations and admissions in patients with COPD with persistent hypercapnic and hypoxic failures.MethodsThe original trial included 74 long-term oxygen-treated patients (31 HFNC treated/43 controls) with persistent hypercapnic fail
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Liu, Jian, Peipei Wang, Luyun Zou, et al. "High-fat, low-carbohydrate diet promotes arrhythmic death and increases myocardial ischemia-reperfusion injury in rats." American Journal of Physiology-Heart and Circulatory Physiology 307, no. 4 (2014): H598—H608. http://dx.doi.org/10.1152/ajpheart.00058.2014.

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High-fat, low-carbohydrate diets (HFLCD) are often eaten by humans for a variety of reasons, but the effects of such diets on the heart are incompletely understood. We evaluated the impact of HFLCD on myocardial ischemia/reperfusion (I/R) using an in vivo model of left anterior descending coronary artery ligation. Sprague-Dawley rats (300 g) were fed HFLCD (60% calories fat, 30% protein, 10% carbohydrate) or control (CONT; 16% fat, 19% protein, 65% carbohydrate) diet for 2 wk and then underwent open chest I/R. At baseline (preischemia), diet did not affect left ventricular (LV) systolic and di
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D’Alessandro, Michelle, Thuva Vanniyasingam, Ashaka Patel, et al. "6 Factors associated with treatment failure of high flow nasal cannula (HFNC) among children with bronchiolitis: a single centre retrospective study." Paediatrics & Child Health 25, Supplement_2 (2020): e2-e3. http://dx.doi.org/10.1093/pch/pxaa068.005.

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Abstract Background Bronchiolitis is the most common viral lower respiratory tract infection in children under two years of age and is the leading cause of hospital admission for children under the age of one year. Respiratory support for bronchiolitis with high flow nasal cannula (HFNC) is increasingly being used outside of critical care areas and in community hospitals. It is important to understand the patient factors associated with HFNC treatment failure in order to identify which patients are at higher risk for requiring escalation of respiratory support and transfer to a pediatric criti
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Kunkely, Horst, and Arnd Vogler. "Photodisproportionation of (1,5-Cyclooctadiene) copper(I) Hexafluoroacetylacetonate Induced by Metal-to-Ligand Charge Transfer Excitation." Zeitschrift für Naturforschung B 58, no. 7 (2003): 704–7. http://dx.doi.org/10.1515/znb-2003-0717.

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The complex CuI(COD)(hfac) with COD = 1,5- cyclooctadiene and hfac = hexafluoroacetyl-acetonate shows two long-wavelength absorptions at λmax = 308 and 241 nm which are assigned to hfac intraligand (IL) and CuI →COD metal-to-ligand charge transfer (MLCT) transitions, respectively. The photolysis of CuI(COD)(hfac) in hexane leads to the release of the olefin and the subsequent disproportionation of CuI(hfac) to elemental copper and CuII(hfac)2 with the quantum yields Φ = 10−3 at λirr =313 nm and Φ = 3×10−3 at λirr = 254 nm. It is suggested that the reactive excited state is of the MLCT type.
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Heijboer, Frank, Laurien Oswald, Sander Cretier, and Gert-Jan Braunstahl. "Pneumomediastinum in a patient with COVID-19 due to diffuse alveolar damage." BMJ Case Reports 14, no. 5 (2021): e242527. http://dx.doi.org/10.1136/bcr-2021-242527.

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A 74-year-old man with COVID-19 was admitted and experienced progressive dyspnoea while receiving supplemental oxygen via high-flow nasal cannula (HFNC). A CT of the thorax showed a pneumomediastinum. The HFNC was temporally interrupted, since it was uncertain whether the positive end-expiratory pressure of the HFNC could be the cause of the pneumomediastinum. After restart of the HFNC, there was no increase of symptoms. We suggest that the pneumomediastinum was the result of COVID-19-related alveolar damage, and not due to the use of HFNC. This observation is relevant since HFNC is often used
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Kamada, Yoshihiro, Shinichi Kiso, Yuichi Yoshida, et al. "Estrogen deficiency worsens steatohepatitis in mice fed high-fat and high-cholesterol diet." American Journal of Physiology-Gastrointestinal and Liver Physiology 301, no. 6 (2011): G1031—G1043. http://dx.doi.org/10.1152/ajpgi.00211.2011.

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Recent studies indicate an accelerated progression of nonalcoholic steatohepatitis (NASH) in postmenopausal women. Hypercholesterolemia, an important risk factor for NASH progression, is often observed after menopause. This study examined the effects of estrogen on NASH in ovariectomized (OVX) mice fed a high-fat and high-cholesterol (HFHC) diet. To investigate the effects of estrogen deficiency, OVX mice and sham-operated (SO) mice were fed normal chow or HFHC diet for 6 wk. Next, to investigate the effects of exogenous estrogen replenishment, OVX mice fed with HFHC diet were treated with imp
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Chang, Gordon Y., Cynthia A. Cox, and Thomas H. Shaffer. "Nasal Cannula, CPAP, and High-Flow Nasal Cannula: Effect of Flow on Temperature, Humidity, Pressure, and Resistance." Biomedical Instrumentation & Technology 45, no. 1 (2011): 69–74. http://dx.doi.org/10.2345/0899-8205-45.1.69.

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Abstract Background: Delivery of warm, humidified, supplemental oxygen via high-flow nasal cannula has several potential benefits; however, the high-flow range may not maintain humidification and temperature and in some cases may cause excessive expiratory pressure loading. Objective: To compare the effect of flow on temperature, humidity, pressure, and resistance in nasal cannula (NC), continuous positive airway pressure (CPAP), and high-flow nasal cannula (HFNC) in a clinical setting. Methods: The three delivery systems were tested in the nursery using each instrument's recommended specifica
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Andino, Ricardo, Gema Vega, Sandra Karina Pacheco, et al. "High-flow nasal oxygen reduces endotracheal intubation: a randomized clinical trial." Therapeutic Advances in Respiratory Disease 14 (January 2020): 175346662095645. http://dx.doi.org/10.1177/1753466620956459.

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Background: The benefits of high-flow nasal cannula (HFNC) as primary intervention in patients with acute hypoxemic respiratory failure (AHRF) are still a matter in debate. Our objective was to compare HFNC therapy versus conventional oxygen therapy (COT) in the prevention of endotracheal intubation in this group of patients. Methods: An open-label, controlled and single-centre clinical trial was conducted in patients with severe AHRF, defined by a PaO2/FIO2 ratio ⩽200, to compare HFNC with a control group (CG) treated by COT delivered through a face mask, with the need to perform intubation a
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Dosman, Cara F., Peter C. Zuberbuhler, Joan I. Tabk, and Richard L. Jones. "Effects of Positive End-Expiratory Pressure on Oscillated Volume during High-Frequency Chest Compression in Children with Cystic Fibrosis." Canadian Respiratory Journal 10, no. 2 (2003): 94–98. http://dx.doi.org/10.1155/2003/792917.

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OBJECTIVE: To investigate the effects of positive end-expiratory pressure (PEEP) on end-expiratory lung volume (EELV) and mean oscillated volume (Vosc) during high frequency chest compression (HFCC).DESIGN: A clinic-based prospective intervention study.SETTING: Pulmonary function laboratory, University of Alberta, Edmonton, Alberta.POPULATION: Nine children with cystic fibrosis with little or no obstructive airway disease who were selected from the outpatient Cystic Fibrosis and Pediatric Pulmonary Clinics at the University of Alberta Hospital, Edmonton, Alberta.METHODS: Each child received HF
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Lee, Young Seok, Sung Won Chang, Jae Kyeom Sim, Sua Kim, and Je Hyeong Kim. "An Integrated Model including the ROX Index to Predict the Success of High-Flow Nasal Cannula Use after Planned Extubation: A Retrospective Observational Cohort Study." Journal of Clinical Medicine 10, no. 16 (2021): 3513. http://dx.doi.org/10.3390/jcm10163513.

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High-flow nasal cannula (HFNC) therapy is commonly used to prevent reintubation after planned extubation. In clinical practice, there are no appropriate tools to evaluate whether HFNC therapy was successful or failed after planned extubation. In this retrospective observational study, we investigated whether the use of the ROX index was appropriate to differentiate between HFNC success and failure within 72 h after extubation and to develop an integrated model including the ROX index to improve the prediction of HFNC success in patients receiving HFNC therapy after planned extubation. Of 276 p
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Yao, Wenjin, Weiwei Sun, Ze Shi, Bingcheng Chen, Le Chen, and Jun Feng. "Blast-Resistant Performance of Hybrid Fiber-Reinforced Concrete (HFRC) Panels Subjected to Contact Detonation." Applied Sciences 10, no. 1 (2019): 241. http://dx.doi.org/10.3390/app10010241.

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This paper experimentally investigates the blast-resistant characteristics of hybrid fiber-reinforced concrete (HFRC) panels by contact detonation tests. The control specimen of plain concrete, polypropylene (PP), polyvinyl alcohol (PVA) and steel fiber-reinforced concrete were prepared and tested for characterization in contrast with PP-Steel HFRC and PVA-Steel HFRC. The sequent contact detonation tests were conducted with panel damage recorded and measured. Damaged HFRC panels were further comparatively analyzed whereby the blast-resistance performance was quantitively assessed via damage co
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Freese, Eric C., Nicholas H. Gist, Rachelle M. Acitelli, et al. "Acute and chronic effects of sprint interval exercise on postprandial lipemia in women at-risk for the metabolic syndrome." Journal of Applied Physiology 118, no. 7 (2015): 872–79. http://dx.doi.org/10.1152/japplphysiol.00380.2014.

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Individuals diagnosed with the metabolic syndrome (MetS) exhibit elevated postprandial lipemia (PPL). The aims of this investigation were to determine 1) if an acute bout of sprint interval training (SIT) attenuates PPL; and 2) if the attenuation of PPL following 6 wk of SIT is magnified compared with a single session of SIT prior to training in women at-risk for MetS ( n = 45; 30–65 yr). Women were randomized to SIT ( n = 22) or a nonexercise control ( n = 23; CON) for 6 wk. Postprandial responses to a high-fat meal challenge (HFMC) were assessed in the CON group before (B-HFMC) and after (Po
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Yuan, Zheng, Neil H. Dryden, Jagadese J. Vittal, and Richard J. Puddephatt. "A binuclear bis{bis(dimethylphosphino)methane}disilver(I) complex with weakly bonded hexafluoroacetylacetonato ligands." Canadian Journal of Chemistry 72, no. 7 (1994): 1605–9. http://dx.doi.org/10.1139/v94-200.

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The new complex [Ag2(hfac)2(μ-dmpm)2] (hfac = hexafluoroacetylacetonato, dmpm = Me2PCH2PMe2) has been prepared and characterized both spectroscopically and by an X-ray structure determination (orthorhombic, Pbca (No. 61), a = 9.960(2), b = 14.694(3), c = 22.548(3) Å, Z = 4, R = 0.0495, Rw = 0.0532). The data indicate that the hfac− ligands have mostly ionic character and it is suggested that this may be responsible for the low volatility of complexes [Ag(hfac)Ln] compared to [Cu(hfac)Ln]; these complexes are of interest as precursors for chemical vapour deposition of silver.
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34

Sanuki, Takuro, Gaku Mishima, Kensuke Kiriishi, et al. "Nitrous Oxide Inhalation Sedation Through a Nasal High-Flow System: The Possibility of a New Technique in Dental Sedation." Anesthesia Progress 64, no. 3 (2017): 175–77. http://dx.doi.org/10.2344/anpr-64-04-06.

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High-flow nasal cannula (HFNC) systems are increasingly used for patients with both acute and chronic respiratory failure because of the clinical effectiveness and patient comfort associated with their use. Recently, HFNC has been used not only as a respiratory support device, but also as a drug delivery system. HFNC is designed to administer heated and humidified inspiratory oxygen flows (100% relative humidity at 37°C). Therefore, HFNC can provide high flows (up to 60 L/min) without discomfort. Moreover, HFNC improves oxygenation by exerting physiologic effects such as (a) dead-space washout
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35

Pawlowski, Valeri, Andreas Strasser, and Arnd Vogler. "Synthesis, Electronic Spectra and Solvent-Induced Reversible Dissociation of Diphosphine(hexafluoroacetylacetonato)copper(I) Complexes." Zeitschrift für Naturforschung B 58, no. 10 (2003): 950–54. http://dx.doi.org/10.1515/znb-2003-1003.

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The complexes CuI(P-P)(hfac) with P-P = 1,2-bis(diphenylphosphino)ethane (diphos), 1,3-bis-(diphenylphosphino)propane (prophos), 2,2’-bis(diphenylphosphino)-1,1’-binaphthyl (binap) and hfac = hexafluoroacetylacetonate were synthesized and spectroscopically characterized. In the solid state or in solutions of non-polar solvents these compounds are yellow owing to a long-wavelength (hfac− →P-P) ligand-to-ligand charge transfer absorption. In coordinating solvents such as CH3CN the complexes undergo a reversible dissociation according to the equation: Cu(P-P)(hfac) + n CH3CN ⇌ [Cu(P-P)(CH3CN)n]+h
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36

Dosman, Cara F., and Richard L. Jones. "High-Frequency Chest Compression: A Summary of the Literature." Canadian Respiratory Journal 12, no. 1 (2005): 37–41. http://dx.doi.org/10.1155/2005/525813.

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The purpose of the present literature summary is to describe high-frequency chest compression (HFCC), summarize its history and outline study results on its effect on mucolysis, mucus transport, pulmonary function and quality of life. HFCC is a mechanical method of self-administered chest physiotherapy, which induces rapid air movement in and out of the lungs. This mean oscillated volume is an effective method of mucolysis and mucus clearance. HFCC can increase independence. Some studies have shown that HFCC leads to more mucus clearance and better lung function compared with conventional ches
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37

ter Wee, René D., and Bernardus J. Thio. "The Effect of High Flow Nasal Cannula Therapy in Exercised-Induced Asthma of Children." Journal of Respiration 1, no. 3 (2021): 197–203. http://dx.doi.org/10.3390/jor1030018.

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High flow nasal cannula (HFNC) therapy is a non-invasive oxygen delivery mode which is safe and well tolerated by adults and children with respiratory distress. HFNC is increasingly used in children with respiratory distress due to mucus retention, such as bronchiolitis and acute asthma. However, he effectiveness of this therapy in acute asthma has not been well researched. To evaluate HFNC for acute childhood asthma, we designed a randomized prospective crossover trial. In the trial, children aged 6–18 years, with a forced expiratory volume in one second (FEV1) lability of ≥30% during an exer
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38

Dafydd, Carwyn, Benjamin J. Saunders, Sarah J. Kotecha, and Martin O. Edwards. "Efficacy and safety of high flow nasal oxygen for children with bronchiolitis: systematic review and meta-analysis." BMJ Open Respiratory Research 8, no. 1 (2021): e000844. http://dx.doi.org/10.1136/bmjresp-2020-000844.

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BackgroundTo assess the published evidence to establish the efficacy and safety of high flow oxygen cannula (HFNC) as respiratory support for children up to 24 months of age with bronchiolitis within acute hospital settings.MethodsWe searched eight databases up to March 2021. Studies including children up to 24 months of age with a diagnosis of bronchiolitis recruited to an randomised controlled trial were considered in the full meta-analysis. At least one arm of the study must include HFNC as respiratory support and report at least one of the outcomes of interest. Studies were identified and
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Kim, Eunhye, Kyeongman Jeon, Dong Kyu Oh, et al. "Failure of High-Flow Nasal Cannula Therapy in Pneumonia and Non-Pneumonia Sepsis Patients: A Prospective Cohort Study." Journal of Clinical Medicine 10, no. 16 (2021): 3587. http://dx.doi.org/10.3390/jcm10163587.

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Despite the increasing use of high-flow nasal cannulas (HFNCs) to treat critically ill patients, data on their effectiveness for sepsis patients remains very limited. We studied a prospective cohort of sepsis patients from the Korean Sepsis Registry (18 intensive care units (ICUs)). Patients started on HFNC therapy for hypoxemia within the first three ICU days were enrolled. HFNC failure was defined as intubation or ICU death, and the primary outcome was early HFNC failure occurring within 72 h of HFNC initiation. Of 901 patients with sepsis admitted to the ICU, 206 who received HFNC therapy w
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Garland, Hilarie. "Impact of high flow nasal cannula implementation on the rate of intubation for bronchiolitis in Canada." Paediatrics & Child Health 23, suppl_1 (2018): e32-e32. http://dx.doi.org/10.1093/pch/pxy054.082.

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Abstract BACKGROUND Bronchiolitis affects more than one-third of children less than two years of age and is the most common reason for admission to hospital in the first year of life. Hospitalization rates have been on the rise, leading to an increase in healthcare expense, morbidity and impact on families. Bronchiolitis can have a heavy burden on health care resources including intubation and Intensive Care Unit (ICU) admissions. Non-invasive respiratory support with high-flow nasal cannula (HFNC) is being used more routinely in paediatric centers, though evidence of efficacy in bronchiolitis
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Kuwata, Seiko, Clara Kurishima, Jeonghye Kim, et al. "Clinical Evaluation of the Hemodynamic Effects of the High-Flow Nasal Cannula Therapy on the Fontan Circulation." Clinical Medicine Insights: Cardiology 9 (January 2015): CMC.S26137. http://dx.doi.org/10.4137/cmc.s26137.

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High-flow nasal cannula (HFNC) therapy supports respiratory effort with a minimal elevation in airway pressure. We examined hemodynamic effects of HFNC therapy in a 10-year-old girl with Fontan circulation, in which positive airway pressure has deleterious hemodynamic effects. The HFNC therapy at 30 L/min improved oxygenation without an increase in central venous pressure. It also reduced heart rate, and systemic and pulmonary vascular resistance, and increased cardiac output. In addition, the HFNC therapy improved the cerebral circulation measured by near-infrared spectroscopy. Thus, HFNC the
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42

Lee, Patrick, and Steven Salhanick. "Carbon Monoxide Poisoning Effectively Treated with High-flow Nasal Cannula." Clinical Practice and Cases in Emergency Medicine 4, no. 1 (2019): 42–45. http://dx.doi.org/10.5811/cpcem.2019.9.43618.

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Carbon monoxide (CO) poisoning is typically treated by administration of oxygen via non-rebreather mask (NRB). High-flow nasal cannula (HFNC) is an alternative to NRB in a variety of disease states. We report a case of the novel use of HFNC in the treatment of acute CO poisoning. A 29-year-old man presented with a carboxyhemoglobin (COHb) level of 29.8%. He was treated with HFNC, and COHb levels declined to 5.4% in 230 minutes. Given several theoretical advantages of HFNC relative to NRB, HFNC is a potential option for use in the treatment of CO poisoning.
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43

Zhuang, Zhen-Jie, Chao-Wen Shan, Bo Li, et al. "Linarin Enriched Extract Attenuates Liver Injury and Inflammation Induced by High-Fat High-Cholesterol Diet in Rats." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/4701570.

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The aim of this study was to explore the potential beneficial effects of linarin enriched Flos Chrysanthemi extract (Lin-extract) on nonalcoholic steatohepatitis (NASH) induced by high-fat high-cholesterol (HFHC) diet in rats. SD rats received normal diet, HFHC diet, or HFHC diet plus different doses of Lin-extract. The liver content of triglyceride and total cholesterol markedly increased in HFHC diet-fed model rats while middle and high dose of Lin-extract lowered liver cholesterol significantly. The expression of stearoyl-CoA desaturase (SCD1) was upregulated by HFHC diet and further elevat
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44

Schwandt, W. Franklin, Toby J. Woods, and Gregory S. Girolami. "Crystal structure of tetrakis(1,1,1,5,5,5-hexafluoroacetylacetonato)hafnium(IV)." Acta Crystallographica Section E Crystallographic Communications 74, no. 8 (2018): 1182–85. http://dx.doi.org/10.1107/s2056989018010514.

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The crystal structure of the title compound, [Hf(C5HF6O2)4], has been determined. The asymmetric unit contains two Hf(hfac)4 molecules (hfac = 1,1,1,5,5,5-hexafluoroacetylacetonate); both are located on general positions and have identical structures apart from the disorder involving three CF3 groups in one of the two molecules. The molecules of Hf(hfac)4 are arranged in layers that are parallel to the ab plane, and the coordination geometry of each hafnium(IV) center is a distorted square antiprism. An interesting aspect of the structure is that the hfac ligands are arranged so that the Hf(hf
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45

Cheng, Chang, Wang, Hsiao, Lai, and Chao. "The Impact of High-Flow Nasal Cannula on the Outcome of Immunocompromised Patients with Acute Respiratory Failure: A Systematic Review and Meta-Analysis." Medicina 55, no. 10 (2019): 693. http://dx.doi.org/10.3390/medicina55100693.

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Background and objectives: High-flow nasal cannula (HFNC) can be used as a respiratory support strategy for patients with acute respiratory failure (ARF). However, no clear evidence exists to support or oppose HFNC use in immunocompromised patients. Thus, this meta-analysis aims to assess the effects of HFNC, compared to conventional oxygen therapy (COT) and noninvasive ventilation (NIV), on the outcomes in immunocompromised patients with ARF. The Pubmed, Embase and Cochrane databases were searched up to November 2018. Materials and Methods: Only clinical studies comparing the effect of HFNC w
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46

Ko, Ryoung-Eun, Chul Park, Jimyoung Nam, et al. "Effect of post-extubation high-flow nasal cannula on reintubation in elderly patients: a retrospective propensity score-matched cohort study." Therapeutic Advances in Respiratory Disease 14 (January 2020): 175346662096849. http://dx.doi.org/10.1177/1753466620968497.

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Background: Studies of mechanically ventilated patients with a low risk of reintubation have suggested that the use of high-flow nasal cannula (HFNC) oxygen therapy reduces the risk of reintubation compared with conventional oxygen therapy (COT). However, the effect of HFNC following extubation in elderly patients with a high risk of reintubation remains unclear. Methods: All consecutive medical intensive care unit (ICU) patients aged &gt;65 years who were mechanically ventilated for &gt;24 h were prospectively registered between July 2017 and June 2018. Control was obtained from a historical
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Dey, Sandip, Chiranjit Biswas, and Jayati Sengupta. "The universally conserved GTPase HflX is an RNA helicase that restores heat-damaged Escherichia coli ribosomes." Journal of Cell Biology 217, no. 7 (2018): 2519–29. http://dx.doi.org/10.1083/jcb.201711131.

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The ribosome-associated GTPase HflX acts as an antiassociation factor upon binding to the 50S ribosomal subunit during heat stress in Escherichia coli. Although HflX is recognized as a guanosine triphosphatase, several studies have shown that the N-terminal domain 1 of HflX is capable of hydrolyzing adenosine triphosphate (ATP), but the functional role of its adenosine triphosphatase (ATPase) activity remains unknown. We demonstrate that E. coli HflX possesses ATP-dependent RNA helicase activity and is capable of unwinding large subunit ribosomal RNA. A cryo–electron microscopy structure of th
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48

Liu, Huifei, William R. Sukov, and Jae Y. Ro. "The t(1;10)(p22;q24) TGFBR3/MGEA5 Translocation in Pleomorphic Hyalinizing Angiectatic Tumor, Myxoinflammatory Fibroblastic Sarcoma, and Hemosiderotic Fibrolipomatous Tumor." Archives of Pathology & Laboratory Medicine 143, no. 2 (2018): 212–21. http://dx.doi.org/10.5858/arpa.2017-0412-ra.

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Context.— Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts, hemosiderotic fibrolipomatous tumor (HFLT), and myxoinflammatory fibroblastic sarcoma (MIFS) are 3 distinct entities of low-grade spindle cell mesenchymal neoplasm. These tumors have similar clinical presentations and partially overlapping but distinctive pathologic features. A recurrent translocation, t(1;10)(p22;q24), has been detected in a subset of PHAT, HFLT, MIFS, and HFLT/MIFS hybrid cases. Translocation t(1;10)(p22;q24) involves transforming growth factor β-receptor 3 (TGFBR3) and meningioma-expressed antigen 5 (
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49

Baird, Ian R., Steven J. Rettig, Brian R. James та Kirsten A. Skov. "Synthesis and X-ray structural characterization of the ruthenium β-diketonato complexes: Ru(hfac)3, cis-Ru(hfac)2(MeCN)2, and cis-Ru(hfac)(acac)(MeCN)2". Canadian Journal of Chemistry 77, № 11 (1999): 1821–33. http://dx.doi.org/10.1139/v99-175.

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Ru(hfac)3 (2) was synthesized via peroxide oxidation of the Ru(II) species [Na][Ru(hfac)3] (1) (hfac = 1,1,1,5,5,5-hexafluoroacetylacetonate). Treatment of either 1 or 2 with CF3SO3H in MeCN generated cis-Ru(hfac)2(MeCN)2 (3). Ru(acac)2(hfac) (4) (acac = acetylacetonate) was generated by addition of hfac to an EtOH solution of cis-[Ru(acac)2(MeCN)2][CF3SO3]. Subsequent treatment of 4 with CF3SO3H in MeCN yielded cis-Ru(acac)(hfac)(MeCN)2 (7). Syntheses of [Na][Ru(hfac)2(acac)] (5) and Ru(hfac)2(acac) (6) are also reported. The complexes were characterized generally by elemental analysis, cycli
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Mei, Guo Dong, Li Hua Xu, Shu Li, and Yin Chi. "Hybrid Effects on Strength of Steel-Polypropylene Hybrid Fiber Reinforced Concrete under Uniaxial and Triaxial Compression." Applied Mechanics and Materials 268-270 (December 2012): 782–87. http://dx.doi.org/10.4028/www.scientific.net/amm.268-270.782.

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Three different volume ratio steel fiber and polypropylene fiber were mixed into concrete matrix to study the hybrid effect of fibers. Cube HFRC specimens were tested under uniaxial and triaxial load. Hybrid effects on compressive strength of the results were analyzed and compared. It was founded that there were positive and negative effects in HFRC under compression. Positive hybrid effects of HFRC could be found when volume ratios of fiber (no less than 1.0% for steel fiber and 0.1% for polypropylene fiber) were added into HFRC.
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