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Journal articles on the topic 'HiCi'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Chen, Y., S. M. Simasko, J. Niggel, W. J. Sigurdson, and F. Sachs. "Ca2+ uptake in GH3 cells during hypotonic swelling: the sensory role of stretch-activated ion channels." American Journal of Physiology-Cell Physiology 270, no. 6 (1996): C1790—C1798. http://dx.doi.org/10.1152/ajpcell.1996.270.6.c1790.

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Hypotonic cell swelling triggers an increase in intracellular Ca2+ concentration that is deemed responsible for the subsequent regulated volume decrease in many cells. To understand the mechanisms underlying this increase, we have studied the Ca2+ sources that contribute to hypotonic cell swelling-induced Ca2+ increase (HICI) in GH3 cells. Fura 2 fluorescence of cell populations revealed that extracellular, but not intracellular, stores of Ca2+ were required. HICI was abolished by nifedipine, a blocker of L-type Ca2+ channels, and Gd3+, a nonspecific blocker of stretch-activated channels (SACs

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2

Womack, Craig S. "Hici: Great-Aunt Lucy, Oklahoma, 1964." Callaloo 17, no. 1 (1994): 122. http://dx.doi.org/10.2307/2932073.

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3

Domingo, Docampo, and Torres-Salinas Daniel. "La nueva lista de investigadores altamente citados de Thomson Reuters y el Ranking de Shanghai: situación de España y mapa universitario." El profesional de la información v. 22, n. 3, (April 29, 2013): 264–71. https://doi.org/10.3145/epi.2013.may.11.

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Unos de los productos de Thomson-Reuters es el listado de investigadores altamente citados, que cobró relevancia a partir de su utilización en el Academic Ranking of World Universities. En el mismo se calcula el indicador HiCi que contabiliza el número de investigadores altamente citados por universidad. Thomson acaba de anunciar una actualización de los listados, en los que han introducido cambios metodológicos relevantes. Se presentan los cambios en los listados de 2013 y el análisis de la distribución por países de los nuevos autores; asimismo se ofrece el listado de los nuevos investigador

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4

Pang, Tony C. Y., Zhihong Xu, Alpha Raj Mekapogu, et al. "HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer." Cancers 13, no. 11 (2021): 2763. http://dx.doi.org/10.3390/cancers13112763.

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Background: Inhibition of hepatocyte growth factor (HGF)/c-MET pathway, a major mediator of pancreatic stellate cell (PSC)−PC cell interactions, retards local and distant cancer progression. This study examines the use of this treatment in preventing PC progression after resection. We further investigate the postulated existence of circulating PSCs (cPSCs) as a mediator of metastatic PC. Methods: Two orthotopic PC mouse models, produced by implantation of a mixture of luciferase-tagged human pancreatic cancer cells (AsPC-1), and human PSCs were used. Model 1 mice underwent distal pancreatectom

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5

Wu, Sixin, and Congshan Zhu. "Formation mechanism of spherical oxide particles containing dye." Journal of Materials Research 14, no. 5 (1999): 2088–91. http://dx.doi.org/10.1557/jmr.1999.0281.

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2-[3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidine)-1-propenyl]-1,3,3-trimethyl-3H-indolium idoide (HICI) dye-doped SiO2 particles were synthesized by sol-gel method. Dimension, diameter, distribution, and homogeneity of the particles are closely related to the positively charged dye concentration, corresponding to the zeta potential of the particles. When the dye concentration reaches about 7.8 × 10−4 mol/mol SiO2, corresponding to the isoelectric point of the particles, the maximum particle size and the most homogeneity can be reached.

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6

Deba, Hakim, Leklou Hakim, and Mohamed Djellaoui. "Sténoses des sinus veineux (SSV) et Hypertension Intracrânienne idiopathique (HICI) : Expérience du service de Neurologie du CHU BEO." Revue Neurologique 175 (April 2019): S24. http://dx.doi.org/10.1016/j.neurol.2019.01.090.

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7

Jørgensen, Mikkel G., Deo P. Pandey, Milena Jaskolska, and Kenn Gerdes. "HicA of Escherichia coli Defines a Novel Family of Translation-Independent mRNA Interferases in Bacteria and Archaea." Journal of Bacteriology 191, no. 4 (2008): 1191–99. http://dx.doi.org/10.1128/jb.01013-08.

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ABSTRACT Toxin-antitoxin (TA) loci are common in free-living bacteria and archaea. TA loci encode a stable toxin that is neutralized by a metabolically unstable antitoxin. The antitoxin can be either a protein or an antisense RNA. So far, six different TA gene families, in which the antitoxins are proteins, have been identified. Recently, Makarova et al. (K. S. Makarova, N. V. Grishin, and E. V. Koonin, Bioinformatics 22:2581-2584, 2006) suggested that the hicAB loci constitute a novel TA gene family. Using the hicAB locus of Escherichia coli K-12 as a model system, we present evidence that su

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8

QUINTERO, WEIR José Ángel. "Hacer en el pensar y Pensar en el hacer: hacia una Otra ciencia." Utopía y Praxis Latinoamericana 29, no. 107 (2024): e13880195. https://doi.org/10.5281/zenodo.13880195.

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Lo que a continuación presentamos, es la transcripción revisada de algunas de las exposiciones que hiciéramos entre el 20 de junio y el 4 de julio, durante las sesiones del Curso-Debate “Hacer en el pensar y Pensar en el hacer: hacia una otra ciencia”, como parte del programa que la UAIN (Universidad Autónoma Indígena), desarrolla de forma virtual. Las mismas están basadas e inspiradas en los escritos y conversaciones personales con el hermano, Carlos Walter Porto-Goncalves, muy particularmente, en dos de sus últimos artículos

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9

Turnbull, Kathryn J., and Kenn Gerdes. "HicA toxin ofEscherichia coliderepresseshicABtranscription to selectively produce HicB antitoxin." Molecular Microbiology 104, no. 5 (2017): 781–92. http://dx.doi.org/10.1111/mmi.13662.

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10

Balbin-Cuesta, Ginette, Greggory Myers, Zesen Lin та ін. "Identifying Novel Regulators of γ-Globin Expression Using a Genome-Scale CRISPR Activation Screen". Blood 142, Supplement 1 (2023): 1100. http://dx.doi.org/10.1182/blood-2023-182203.

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β-hemoglobinopathies are the most common monogenic disorders worldwide, and are defined based on whether patients have quantitative (β-thalassemia) or qualitative (Sickle Cell Disease (SCD)) defects in β-globin synthesis. Unfortunately, there are limited treatment options for β-hemoglobinopathies, and the majority of patients continue to develop life-threatening complications from their diseases. An alternative β-like subunit, γ-globin, has been shown to inhibit pathogenic hemoglobin polymerization in SCD and to functionally replace β-globin in β-thalassemia. The discovery of novel strategies

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11

Daimon, Yasushi, Shin-ichiro Narita та Yoshinori Akiyama. "Activation of Toxin-Antitoxin System Toxins Suppresses Lethality Caused by the Loss of σEin Escherichia coli". Journal of Bacteriology 197, № 14 (2015): 2316–24. http://dx.doi.org/10.1128/jb.00079-15.

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ABSTRACTσE, an alternative σ factor that governs a major signaling pathway in envelope stress responses in Gram-negative bacteria, is essential for growth ofEscherichia colinot only under stressful conditions, such as elevated temperature, but also under normal laboratory conditions. A mutational inactivation of thehicBgene has been reported to suppress the lethality caused by the loss of σE.hicBencodes the antitoxin of the HicA-HicB toxin-antitoxin (TA) system; overexpression of the HicA toxin, which exhibits mRNA interferase activity, causes cleavage of mRNAs and an arrest of cell growth, wh

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12

Bagabas, Salwa S., Jorge Trujillo-Mendoza, Michael J. Stocks, David P. J. Turner, and Neil J. Oldfield. "The Characterization of a Gonococcal HicAB Toxin–Antitoxin System Capable of Causing Bacteriostatic Growth Arrest." Microorganisms 13, no. 7 (2025): 1619. https://doi.org/10.3390/microorganisms13071619.

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Neisseria gonorrhoeae is the causative agent of the sexually transmitted infection gonorrhea. Preventative vaccines or novel treatments based on a better understanding of the molecular basis of N. gonorrhoeae infection are required as resistance to current antibiotics is widespread. Toxin–antitoxin (TA) systems modulate bacterial physiology by interfering with vital cellular processes; type II TA systems, where both toxin and antitoxin are proteins, are the best-studied. Bioinformatics analysis revealed genes encoding an uncharacterized type II HicAB TA system in the N. gonorrhoeae strain FA10

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13

Winter, Ashley J., Christopher Williams, Michail N. Isupov, et al. "The molecular basis of protein toxin HicA–dependent binding of the protein antitoxin HicB to DNA." Journal of Biological Chemistry 293, no. 50 (2018): 19429–40. http://dx.doi.org/10.1074/jbc.ra118.005173.

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14

Martei, Yehoda M., Kotoji Iwamoto, Ronald D. Barr, John T. Wiernkowski, and Jane Robertson. "Shortages and price variability of essential cytotoxic medicines for treating children with cancers." BMJ Global Health 5, no. 11 (2020): e003282. http://dx.doi.org/10.1136/bmjgh-2020-003282.

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IntroductionLow-income and middle-income countries (LMICs) face the largest burden of mortality from childhood cancers with limited access to curative therapies. Few comparative analyses across all income groups and world regions have examined the availability and acquisition costs of essential medicines for treating cancers in children.MethodsA cross-sectional survey involved countries in five income groups—low-income (LIC), lower-middle-income (LMC), upper-middle-income (UMC), two high-income country groups (HIC1, HIC2). Physicians and pharmacists reported institutional use, availability, st

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15

Xie, Zhoujie, Fengxia Qi, and Justin Merritt. "Development of a Tunable Wide-Range Gene Induction System Useful for the Study of Streptococcal Toxin-Antitoxin Systems." Applied and Environmental Microbiology 79, no. 20 (2013): 6375–84. http://dx.doi.org/10.1128/aem.02320-13.

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ABSTRACTDespite the plethora of genetic tools that have been developed for use inStreptococcus mutans, theS. mutansgenetic system still lacks an effective gene induction system exhibiting low basal expression and strong inducibility. Consequently, we created two hybrid gene induction cassettes referred to as Xyl-S1 and Xyl-S2. Both Xyl-S cassettes are xylose inducible and controlled by theBacillus megateriumxylose repressor. The Xyl-S cassettes each demonstrated >600-fold-increased reporter activity in the presence of 1.2% (wt/vol) xylose. However, the Xyl-S1 cassette yielded a much higher

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16

Azimi, Iman, Arman Anzanpour, Amir M. Rahmani, et al. "HiCH." ACM Transactions on Embedded Computing Systems 16, no. 5s (2017): 1–20. http://dx.doi.org/10.1145/3126501.

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17

Simms, Matthew. "Hisako Hibi and Matsusaburo “George” Hibi Papers." Archives of American Art Journal 62, no. 1 (2023): 93–94. http://dx.doi.org/10.1086/725127.

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18

Plantinga, Alvin. "Ad Hick." Faith and Philosophy 14, no. 3 (1997): 295–98. http://dx.doi.org/10.5840/faithphil199714333.

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19

CHEETHAM, DAVID. "JOHN HICK." Religious Studies 48, no. 3 (2012): 277–79. http://dx.doi.org/10.1017/s0034412512000212.

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20

Moore, Steven. "Hick Apocalyptics." American Book Review 35, no. 4 (2014): 7. http://dx.doi.org/10.1353/abr.2014.0084.

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21

Yang, Jingsi, Bingshuang Xu, Zengqiang Gao, et al. "HicAB toxin–antitoxin complex fromEscherichia coli: expression and crystallization." Acta Crystallographica Section F Structural Biology Communications 73, no. 9 (2017): 505–10. http://dx.doi.org/10.1107/s2053230x17011529.

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Toxin–antitoxin (TA) systems are widespread in both bacteria and archaea, where they enable cells to adapt to environmental cues. TA systems play crucial roles in various cellular processes, such as programmed cell death, cell growth, persistence and virulence. Here, two distinct forms of the type II toxin–antitoxin complex HicAB were identified and characterized inEscherichia coliK-12, and both were successfully overexpressed and purified. The two proposed forms, HicABLand HicABS, differed in the presence or absence of a seven-amino-acid segment at the N-terminus in the antitoxin HicB. The sh

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22

Matin, Ibrahim, and Simiyu Kisurulia. "Ubunifu na Mwonoulimwengu wa Mwandishi: Mifano ya Kazi za Ken Walibora." East African Journal of Swahili Studies 7, no. 1 (2024): 253–71. http://dx.doi.org/10.37284/jammk.7.1.1954.

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Katika kazi ya fasihi, mawazo, mafunzo na falsafa ya msanii hubainisha msimamo wake kuhusu masuala mbalimbali ya kijamii. Msimamo ni ile hali ya mwandishi kuamua kufuata na kushikilia jambo fulani. Jambo hili huweza kukataliwa na wengi lakini akalishikilia tu. Msimamo ndio huweza kuwatofautisha wasanii wawili au zaidi wanaoandika kuhusu mazingira yanayofanana. Hili ambalo msanii anashikilia sana ndilo tunaloita katika utafiti huu kuwa mwonoulimwengu wa mwandishi. Ni vyema kujiuliza ni mambo gani yanayomsukuma na kuchochea mwandishi Ken Walibora kuchukua mawazo, msimamo na mkondo fulani katika

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23

Pentz, Rebecca. "Hick and Saints." Faith and Philosophy 8, no. 1 (1991): 96–103. http://dx.doi.org/10.5840/faithphil1991817.

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24

Alston, William P. "Response to Hick." Faith and Philosophy 14, no. 3 (1997): 287–88. http://dx.doi.org/10.5840/faithphil199714328.

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25

THANG, L. L. "Shikusutizu no Hibi." Social Science Japan Journal 10, no. 1 (2007): 134–37. http://dx.doi.org/10.1093/ssjj/jym002.

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26

Pitt, Jack. "Hick on Evil." Teaching Philosophy 12, no. 2 (1989): 141–44. http://dx.doi.org/10.5840/teachphil198912232.

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27

Ccorahua, Robert, Anika Eca, Pablo Ramírez, et al. "Comparative genomic analysis of two novel plasmids from Acidithiobacillus ferrivorans strain PQ33." Revista Peruana de Biología 28, no. 1 (2021): e19743. http://dx.doi.org/10.15381/rpb.v28i1.19743.

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Acidithiobacillus ferrivorans is a psychrotolerant acidophile capable of growing and oxidizing ferrous and sulphide substrates at low temperatures. To date, six genomes of this organism have been characterized; however, evidence of a plasmid in this species has been reported only once, whereby there is no conclusive role of the plasmids in the species. Herein, two novel plasmids of A. ferrivorans PQ33 were molecularly characterized and compared at a genomic scale. The genomes of two plasmids (12 kbp and 10 kbp) from A. ferrivorans PQ33 (NZ_LVZL01000000) were sequenced and annotated. The plasmi

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28

Poudel, Govinda Prasad. "Rehabilitation Issue of Stone Spouts as a Part of an Alternative Source of Public Water Supply Scheme Within Lalitpur Metropolitian City Area." Journal of Innovations in Engineering Education 3, no. 1 (2020): 50–53. http://dx.doi.org/10.3126/jiee.v3i1.34325.

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Stone spouts of LMC can be classified according to the water availability. Out of sixty-one stone spouts, only twelve numbers of stone spouts were effectively running up to 2006. These are Manga Hiti, Iku Hiti, Sincha Hiti, Haku Hiti, Konti Hiti, Alko Hiti, Chyasa Hiti, Sundhara, Tapa Hiti(a), Wasa Hiti, Tanga Hiti and Shova Hiti. These stone spouts are considered as good type according to availability of water. Remaining out of fourty- nine stone spouts thirty-four are less effective i.e average type and fifteen are dried up and not exist up to 2006. Comparing different scenarios and results

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Chen, Yongwu, Chongwei Wang, Hui Yang, et al. "Epidemiology of Drug- and Herb-Induced Liver Injury Assessed for Causality Using the Updated RUCAM in Two Hospitals from China." BioMed Research International 2021 (February 23, 2021): 1–7. http://dx.doi.org/10.1155/2021/8894498.

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Drug- and herb-induced liver injury (DILI and HILI) is an increasingly common and serious condition. Here, data for DILI and HILI patients from two large tertiary hospitals were retrospectively analyzed. Patient characteristics, causes and severity of DILI and HILI, the correlation between expression of p62 and the severity of DILI and HILI, treatment of DILI and HILI, and the prognostic factors of DILI and HILI were studied. A total of 82 patients with DILI and HILI were recruited for the study. Most patients presented with hepatocellular injury, followed by cholestatic injury and mixed injur

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30

Van Rechem, Capucine, Gaylor Boulay, Sébastien Pinte, Nicolas Stankovic-Valentin, Cateline Guérardel, and Dominique Leprince. "Differential Regulation of HIC1 Target Genes by CtBP and NuRD, via an Acetylation/SUMOylation Switch, in Quiescent versus Proliferating Cells." Molecular and Cellular Biology 30, no. 16 (2010): 4045–59. http://dx.doi.org/10.1128/mcb.00582-09.

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ABSTRACT The tumor suppressor gene HIC1 encodes a transcriptional repressor involved in regulatory loops modulating P53-dependent and E2F1-dependent cell survival, growth control, and stress responses. Despite its importance, few HIC1 corepressors and target genes have been characterized thus far. Using a yeast two-hybrid approach, we identify MTA1, a subunit of the NuRD complex, as a new HIC1 corepressor. This interaction is regulated by two competitive posttranslational modifications of HIC1 at lysine 314, promotion by SUMOylation, and inhibition by acetylation. Consistent with the role of H

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31

Makhlin, Igor. "Gröbner fans of Hibi ideals, generalized Hibi ideals and flag varieties." Journal of Combinatorial Theory, Series A 185 (January 2022): 105541. http://dx.doi.org/10.1016/j.jcta.2021.105541.

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32

Mages, Stephan, Ole Hensel, Antonia Maria Zierz, Torsten Kraya, and Stephan Zierz. "Experimental provocation of ‘ice-cream headache’ by ice cubes and ice water." Cephalalgia 37, no. 5 (2016): 464–69. http://dx.doi.org/10.1177/0333102416650704.

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Background There are various studies on experimentally provoked ‘ice-cream headache’ or ‘headache attributed to ingestion or inhalation of a cold stimulus’ (HICS) using different provocation protocols. The aim of this study was to compare two provocation protocols. Methods Ice cubes pressed to the palate and fast ingestion of ice water were used to provoke HICS and clinical features were compared. Results The ice-water stimulus provoked HICS significantly more often than the ice-cube stimulus (9/77 vs. 39/77). Ice-water-provoked HICS had a significantly shorter latency (median 15 s, range 4–97

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33

Liu, Lirong, Qi Wang, Shuang Qin, Chang Su, Xin Hai, and Zhenkuan Yuan. "Comprehensive characterization of the competitive endogenous RNA network revealing its immune-related functions in hepatic ischemia-reperfusion injury." PLOS One 20, no. 7 (2025): e0327101. https://doi.org/10.1371/journal.pone.0327101.

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Hepatic ischemia-reperfusion injury (HIRI) is a common complication in liver surgery and transplantation. Recent studies have revealed the significant role of the competing endogenous RNA (ceRNA) network in HIRI. Herein, we comprehensively analyzed the HIRI-related ceRNA network and its correlation with immune-related pathways and immune cells in HIRI patients. We identified 449 lncRNAs, 26 miRNAs, and 548 mRNAs differentially expressed in HIRI patients. We constructed a HIRI-related ceRNA network in liver transplant patients consisting of 3 lncRNAs, 3 miRNAs, and 29 mRNAs. Biological function

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34

Stankovic-Valentin, Nicolas, Sophie Deltour, Jacob Seeler та ін. "An Acetylation/Deacetylation-SUMOylation Switch through a Phylogenetically Conserved ψKXEP Motif in the Tumor Suppressor HIC1 Regulates Transcriptional Repression Activity". Molecular and Cellular Biology 27, № 7 (2007): 2661–75. http://dx.doi.org/10.1128/mcb.01098-06.

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ABSTRACT Tumor suppressor HIC1 (hypermethylated in cancer 1) is a gene that is essential for mammalian development, epigenetically silenced in many human tumors, and involved in a complex pathway regulating P53 tumor suppression activity. HIC1 encodes a sequence-specific transcriptional repressor containing five Krüppel-like C2H2 zinc fingers and an N-terminal BTB/POZ repression domain. Here, we show that endogenous HIC1 is SUMOylated in vivo on a phylogenetically conserved lysine, K314, located in the central region which is a second repression domain. K314R mutation does not influence HIC1

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35

Sumi, Koichiro, Misato Sakuda, Kinuyo Munakata, Kentaro Nakamura та Kinya Ashida. "α-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFα/IFNγ Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube". Nutrients 13, № 7 (2021): 2391. http://dx.doi.org/10.3390/nu13072391.

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There is ongoing debate as to whether or not α-hydroxyisocaproic acid (HICA) positively regulates skeletal muscle protein synthesis resulting in the gain or maintenance of skeletal muscle. We investigated the effects of HICA on mouse C2C12 myotubes under normal conditions and during cachexia induced by co-exposure to TNFα and IFNγ. The phosphorylation of AMPK or ERK1/2 was significantly altered 30 min after HICA treatment under normal conditions. The basal protein synthesis rates measured by a deuterium-labeling method were significantly lowered by the HICA treatment under normal and cachexic

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Hua, Yanguo, and Yinfeng Zhang. "Analysis of the Therapeutic Effect of ZhenGan XiFeng Decoction in the Acute Phase of Hypertensive Intracerebral Hemorrhage." Journal of Clinical and Nursing Research 9, no. 5 (2025): 214–20. https://doi.org/10.26689/jcnr.v9i5.10694.

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Objective: To analyze the therapeutic effect of ZhenGan XiFeng Decoction in patients with hypertensive intracerebral hemorrhage (HICH) in the acute phase. Methods: Fifty-seven patients with HICH in the acute phase who visited the hospital from April 2024 to March 2025 were selected as samples and randomly divided into two groups. Group A received combined therapy with ZhenGan XiFeng Decoction, while Group B received conventional treatment. The efficacy, blood pressure, and symptom scores were compared between the two groups. Results: The effective rate of HICH patients in Group A was higher th

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37

WATANABE, Shujun. "Buddhism on Mt. Hiei." JOURNAL OF INDIAN AND BUDDHIST STUDIES (INDOGAKU BUKKYOGAKU KENKYU) 41, no. 2 (1993): 631–36. http://dx.doi.org/10.4259/ibk.41.631.

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38

Farid, Arifa. "JOHN HICK ON GOD." Islamic Studies 38, no. 2 (1999): 275–87. https://doi.org/10.52541/isiri.v38i2.6131.

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39

Badham, Paul. "Book Review: John Hick." Theology 107, no. 837 (2004): 209–10. http://dx.doi.org/10.1177/0040571x0410700310.

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40

Miyazaki, Mitsuhiro. "Almost Gorenstein Hibi rings." Journal of Algebra 493 (January 2018): 135–49. http://dx.doi.org/10.1016/j.jalgebra.2017.09.033.

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41

McMullen, M. S., D. C. Doehlert, and J. D. Miller. "Registration of ‘HiFi’ Oat." Crop Science 45, no. 4 (2005): 1664. http://dx.doi.org/10.2135/cropsci2005.003.

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42

Ene, Viviana. "Syzygies of Hibi Rings." Acta Mathematica Vietnamica 40, no. 3 (2015): 403–46. http://dx.doi.org/10.1007/s40306-015-0117-0.

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43

Vidal, Xavier Medina, and Zessna García Ríos. "“Lo Hice por Ellos”." Aztlán: A Journal of Chicano Studies 42, no. 2 (2017): 195–210. http://dx.doi.org/10.1525/azt.2017.42.2.195.

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44

Kulaleen, Aranscha R., and Cl Pattinama. "Remaja Bermasalah Hukum di Panti Sosial Hiti-Hiti Hala-Hala: Kajian Pastoral." ARUMBAE: Jurnal Ilmiah Teologi dan Studi Agama 2, no. 2 (2020): 167–82. http://dx.doi.org/10.37429/arumbae.v2i2.490.

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These teenagers need encouragement and motivation and strengthening in dealing with every case they have. For them, the problems they face have considerably narrowed the space for movement. They can no longer have more time together with their families. They are not free to express themselves at school. They are no longer able to play and hang out like teenagers in general. The problem faced by these teenagers is the findings of research conducted at the Social Home of Hiti-hiti Hala-hala. With pastoral studies, researchers found that there is real support in the form of pastoral care. Adolesc

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Pérez, Jenniffer, Alex González, David Galarza-Bernita, and John A. Cuenca. "Niveles altos de hemoglobina glicosilada se asocian a hemorragia intracerebral espontánea: Estudio de casos y controles." Revista Ecuatoriana de Neurologia 30, no. 3 (2022): 31–37. http://dx.doi.org/10.46997/revecuatneurol30300031.

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Introducción: Existe evidencia de la asociación entre valores de hemoglobina glicosilada (HbA1C) con hemorragia intracerebral espontánea (HICE). Sin embargo, los reportes en pacientes latinoamericanos son escasos. Objetivo: Determinar si HbA1c es factor de riesgo de HICE. Métodos: Se realiza un estudio de casos y controles. Los casos fueron pacientes hospitalizados con HICE, los controles fueron pacientes diabéticos ambulatorios del mismo grupo etario. Calculamos la asociación entre factores de riesgo de HICE mediante la regresión logística. Resultados: Se identificaron 45 casos y 45 controles

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Xu, Yiping, Yili Chen, Mengxia Yao, et al. "MicroRNA-146a Improved Acute Lung Injury Induced by hepatic Ischemia-reperfusion Injury by Inhibiting PRDX1." Dose-Response 21, no. 2 (2023): 155932582311698. http://dx.doi.org/10.1177/15593258231169805.

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Hepatic ischemia-reperfusion injury (HIRI)–induced acute lung injury (ALI) is characterized by high incidence and poor prognosis. The regulatory role of microRNA-146a (miR-146a) in HIRI has been reported, but if miR-146a could affect the progression of HIRI-induced ALI has not been reported. The mice HIRI model was established by ligating left hepatic portal vein and hepatic artery for 60 minutes and then treating with reperfusion for 4 hours. Hypoxia-reoxygenation (HR) was performed to establish cell model. The binding site between miR-146a and Peroxidase 1 (PRDX1) was predicted and validated

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Ming, Nuo, Ha Sen Ta Na, Jin-Ling He, Qing-Tao Meng, and Zhong-Yuan Xia. "Propofol alleviates oxidative stress via upregulating lncRNA-TUG1/Brg1 pathway in hypoxia/reoxygenation hepatic cells." Journal of Biochemistry 166, no. 5 (2019): 415–21. http://dx.doi.org/10.1093/jb/mvz054.

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Abstract Reducing oxidative stress is an effective method to prevent hepatic ischaemia/reperfusion injury (HIRI). This study focuses on the role of propofol on the oxidative stress of hepatic cells and the involved lncRNA-TUG1/Brahma-related gene 1 (Brg1) pathway in HIRI mice. The mouse HIRI model was established and was intraperitoneally injected with propofol postconditioning. Hepatic injury indexes were used to evaluate HIRI. The oxidative stress was indicated by increasing 8-isoprostane concentration. Mouse hepatic cell line AML12 was treated with hypoxia and subsequent reoxygenation (H/R)

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Deek, Mathew Pierre, Kim Van der Eecken, Phillip Sutera, et al. "Long-term outcomes and genetic predictors of response to metastasis-directed therapy versus observation in oligometastatic castration-sensitive prostate cancer: A pooled analysis of the STOMP and ORIOLE trials." Journal of Clinical Oncology 40, no. 16_suppl (2022): 5025. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.5025.

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5025 Background: Prospective reports suggest metastasis directed therapy (MDT) in oligometastatic castration sensitive prostate cancer (omCSPC) is associated with improved treatment outcomes. Here we present long term outcomes of the phase II STOMP and ORIOLE trials and assess the ability of a high-risk (HiRi) mutational signature to provide prognostic and predictive information regarding MDT response. Methods: Patients with omCSPC (< 3 lesions) enrolled on STOMP (n = 62) and ORIOLE (n = 54) randomized to MDT or observation were pooled. The primary endpoint was progression-free survival (PF

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Deek, Mathew Pierre, Kim Van der Eecken, Phillip Sutera, et al. "Long-term outcomes and genetic predictors of response to metastasis-directed therapy versus observation in oligometastatic castration-sensitive prostate cancer: A pooled analysis of the STOMP and ORIOLE trials." Journal of Clinical Oncology 40, no. 16_suppl (2022): 5025. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.5025.

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5025 Background: Prospective reports suggest metastasis directed therapy (MDT) in oligometastatic castration sensitive prostate cancer (omCSPC) is associated with improved treatment outcomes. Here we present long term outcomes of the phase II STOMP and ORIOLE trials and assess the ability of a high-risk (HiRi) mutational signature to provide prognostic and predictive information regarding MDT response. Methods: Patients with omCSPC (< 3 lesions) enrolled on STOMP (n = 62) and ORIOLE (n = 54) randomized to MDT or observation were pooled. The primary endpoint was progression-free survival (PF

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Qureshi, Ayesha Asloob. "Indispensable Hibi Relations and Gröbner Bases." Algebra Colloquium 22, no. 04 (2015): 567–80. http://dx.doi.org/10.1142/s1005386715000498.

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In this paper we consider Hibi rings and Rees rings attached to a poset. We classify the ideal lattices of posets whose Hibi relations are indispensable and the ideal lattices of posets whose Hibi relations form a quadratic Gröbner basis with respect to the rank lexicographic order. Similar classifications are obtained for Rees rings of Hibi ideals.

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