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Journal articles on the topic 'HICUM model'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 February 2022

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1

Tseng, S. C., C. C. Meng, W. Y. Chen, and J. Y. Su. "A modified HICUM model for GaInP/GaAs HBT devices." Microwave and Optical Technology Letters 48, no. 4 (2006): 780–83. http://dx.doi.org/10.1002/mop.21474.

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Sun, Ya-Bin, Jun Fu, Yu-Dong Wang, Wei Zhou, Wei Zhang, and Zhi-Hong Liu. "Extraction of temperature dependences of small-signal model parameters in SiGe HBT HICUM model." Chinese Physics B 25, no. 4 (2016): 048501. http://dx.doi.org/10.1088/1674-1056/25/4/048501.

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3

Saha, Bishwadeep, Sebastien Fregonese, Anjan Chakravorty, Soumya Ranjan Panda, and Thomas Zimmer. "Sub-THz and THz SiGe HBT Electrical Compact Modeling." Electronics 10, no. 12 (2021): 1397. http://dx.doi.org/10.3390/electronics10121397.

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From the perspectives of characterized data, calibrated TCAD simulations and compact modeling, we present a deeper investigation of the very high frequency behavior of state-of-the-art sub-THz silicon germanium heterojunction bipolar transistors (SiGe HBTs) fabricated with 55-nm BiCMOS process technology from STMicroelectronics. The TCAD simulation platform is appropriately calibrated with the measurements in order to aid the extraction of a few selected high-frequency (HF) parameters of the state-of-the-art compact model HICUM, which are otherwise difficult to extract from traditionally prepa

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4

Liu, Hao, Zhongqiu Wang, Junwen Zhang, et al. "Porcine traumatic lung injury model induced by hilum clamping." Injury 40, no. 9 (2009): 956–62. http://dx.doi.org/10.1016/j.injury.2009.04.001.

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5

DeSimone, Kevin, and Keith A. Schneider. "Distinguishing Hemodynamics from Function in the Human LGN Using a Temporal Response Model." Vision 3, no. 2 (2019): 27. http://dx.doi.org/10.3390/vision3020027.

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We developed a temporal population receptive field model to differentiate the neural and hemodynamic response functions (HRF) in the human lateral geniculate nucleus (LGN). The HRF in the human LGN is dominated by the richly vascularized hilum, a structure that serves as a point of entry for blood vessels entering the LGN and supplying the substrates of central vision. The location of the hilum along the ventral surface of the LGN and the resulting gradient in the amplitude of the HRF across the extent of the LGN have made it difficult to segment the human LGN into its more interesting magnoce

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Phuangsombut, Kaewkarn, Nattaporn Suttiwijitpukdee, and Anupun Terdwongworakul. "Nondestructive classification of mung bean seeds by single kernel near-infrared spectroscopy." Journal of Innovative Optical Health Sciences 10, no. 03 (2017): 1650053. http://dx.doi.org/10.1142/s179354581650053x.

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Near-infrared spectroscopy (NIRS) in the range 900–1700 nm was performed to develop a classifying model for dead seeds of mung bean using single kernel measurements. The use of the combination of transmission-absorption spectra and reflection-absorption spectra was determined to yield a better classification performance (87.88%) than the use of only transmission-absorption spectra (81.31%). The effect of the orientation of the mung bean with respect to the light source on its absorbance was investigated. The results showed that hilum-down orientation exhibited the highest absorbance compared t

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GOMES, Helbert Minuncio Pereira, Leonardo Carvalho SERIGIOLLE, Daren Athiê Boy RODRIGUES, Carolina Marques LOPES, Sarah do Valle STUDART, and Pedro Luiz Squilacci LEME. "Unfeasible experimental model of normothermic hepatic ischemia and reperfusion in rats using the Pringle maneuver." ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 27, no. 3 (2014): 196–200. http://dx.doi.org/10.1590/s0102-67202014000300009.

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BACKGROUND: The negative result of a research does not always indicate failure, and when the data do not permit a proper conclusion, or are contrary to the initial project, should not simply be discarded and archived. AIM: To report failure after performing experimental model of liver ischemia and reperfusion normothermic, continuous or intermittent, in small animals aiming at the study of biochemical and histological parameters after postoperative recovery. METHODS: Fifteen Wistar rats were divided into three groups of five animals each; all underwent surgery, the abdomen was sutured after th

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Connell, L. W., F. W. Sexton, and A. K. Prinja. "Further development of the Heavy Ion Cross section for single event UPset: model (HICUP)." IEEE Transactions on Nuclear Science 42, no. 6 (1995): 2026–34. http://dx.doi.org/10.1109/23.489249.

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Hosseinpour, Mehrdad, AmirHossein Irajpour, and Naghmeh Poorjam. "The effect of splenic hilum ligation on the injured spleen and its function in rat model." Archives of Trauma Research 8, no. 1 (2019): 6. http://dx.doi.org/10.4103/atr.atr_49_18.

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10

Juntermanns, Benjamin, Florian Grabellus, Hongwei Zhang, et al. "Vascular and Nerval Damage After Intraoperative Radiation Therapy of the Liver Hilum in a Large Animal Model." Journal of Investigative Surgery 27, no. 3 (2013): 163–68. http://dx.doi.org/10.3109/08941939.2013.868961.

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11

Barion, Giuseppe, Giuliano Mosca, and Teofilo Vamerali. "Estimation of cotyledon isoflavone abundance by a grey luminance-based model in variously hilum-coloured soybean varieties." Journal of the Science of Food and Agriculture 96, no. 12 (2016): 4126–34. http://dx.doi.org/10.1002/jsfa.7613.

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12

Nagy, Agnes, Alicia Polanco, and Manuel Alvarez. "Modeling and Extraction of Parameters Based on Physical Effects in Bipolar Transistors." Active and Passive Electronic Components 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/895247.

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The rising complexity of electronic systems, the reduction of components size, and the increment of working frequencies demand every time more accurate and stable integrated circuits, which require more precise simulation programs during the design process. PSPICE, widely used to simulate the general behavior of integrated circuits, does not consider many of the physical effects that can be found in real devices. Compact models, HICUM and MEXTRAM, have been developed over recent decades, in order to eliminate this deficiency. This paper presents some of the physical aspects that have not been

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13

Costa, Ana Da Silva, Peter Mortensen, Maria P. Hortigon-Vinagre, et al. "Electrophysiology of hiPSC-Cardiomyocytes Co-Cultured with HEK Cells Expressing the Inward Rectifier Channel." International Journal of Molecular Sciences 22, no. 12 (2021): 6621. http://dx.doi.org/10.3390/ijms22126621.

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The immature electrophysiology of human-induced pluripotent stem cell-derived cardiomyocytes (hiCMs) complicates their use for therapeutic and pharmacological purposes. An insufficient inward rectifying current (IK1) and the presence of a funny current (if) cause spontaneous electrical activity. This study tests the hypothesis that the co-culturing of hiCMs with a human embryonic kidney (HEK) cell-line expressing the Kir2.1 channel (HEK-IK1) can generate an electrical syncytium with an adult-like cardiac electrophysiology. The mechanical activity of co-cultures using different HEK-IK1:hiCM rat

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Oliveira-Freitas, Vera L., Leonardo Dalla Giacomassa Rocha Thomaz, Lucas Elias Lise Simoneti, et al. "RC-3095, a Selective Gastrin-Releasing Peptide Receptor Antagonist, Does Not Protect the Lungs in an Experimental Model of Lung Ischemia-Reperfusion Injury." BioMed Research International 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/496378.

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RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation. However, its protective effect on lungs submitted to lung ischemia-reperfusion injury has not been addressed before. Then, we administrated RC-3095 intravenously before and after lung reperfusion using an animal model of lung ischemia-reperfusion injury (LIRI) by clamping the pulmonary hilum. Twenty Wistar rats were subjected to an experimental model in four groups: SHAM, ischemia-reperfusion (IR), RC-Pre, and RC-Post. The final mean arterial pressure significantly dec

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15

Tinnel, B., M. S. Mendonca, M. Henderson, et al. "Pulmonary Hilar Stereotactic Body Radiation Therapy in the Rat." Technology in Cancer Research & Treatment 6, no. 5 (2007): 425–31. http://dx.doi.org/10.1177/153303460700600508.

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Stereotactic Body Radiation therapy (SBRT) is an emerging modality of treatment for early stage non-small cell lung carcinoma. Concerns have arisen related to increased toxicities for medial tumors. We have developed a model of high dose, hypofractionated radiotherapy to the pulmonary hilum using the Leksell Gamma-Knife™. Sprague-Dawley rats received hypofractionated SBRT to the unilateral lung hilum using a custom immobilization device on the Gamma Knife. Each animal was individually scanned, treatment planned, and treated with either two 4 mm or one 8 mm collimated shots at escalating doses

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16

Bassett, Mark J., and Arie Blom. "A New Genotype for White Seed Coat Discovered in `Early Wax' Snap Bean." Journal of the American Society for Horticultural Science 116, no. 1 (1991): 131–36. http://dx.doi.org/10.21273/jashs.116.1.131.

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The white-seeded snap bean `Early Wax' (Phaseolus vulgaris L.) was crossed with a black-seeded breeding line 5-593. The F2 segregation data are consistent with a three-gene model, in which all three genes must be homozygous recessive to give white seed coat. One of the genes is t because of segregation in F2 for plants with white flowers and partial seed coat coloration. We hypothesize that the genes ers and ers2 in the presence of f block all seed color expression in all genes for partial coloration of seed. The hypothesis of three recessive genes was confirmed in a backcross test involving `

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17

Pfaff, Kathryn A., Lisa Dolovich, Michelle Howard, Deborah Sattler, Merrick Zwarenstein, and Denise Marshall. "Unpacking ‘the cloud’: a framework for implementing public health approaches to palliative care." Health Promotion International 35, no. 1 (2019): 160–70. http://dx.doi.org/10.1093/heapro/day123.

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Summary Designing and implementing population-based systems of care that address the social determinants of health, take action on multiple levels, and are guided by evidence-based principles is a pressing priority, and an international challenge. Aging persons are a priority demographic whose health needs span physical, psychosocial and existential care domains, increase in the last year of life, are often poorly coordinated and therefore remain unmet. Compassionate communities (CCs) are an example of a public health approach that fully addresses the holistic healthcare needs of those who are

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18

Ito, Hiroki, Kazuhide Makiyama, Takashi Kawahara, et al. "Modified C index: Novel predictor of postoperative renal functional loss of laparoscopic partial nephrectomy." Canadian Urological Association Journal 11, no. 5 (2017): 215. http://dx.doi.org/10.5489/cuaj.4192.

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Introduction: We aimed to develop a scoring system to quantify the distance between the renal hilum and renal tumour, termed the modified C index (m-CI), and to predict renal functional loss (RFL)following laparoscopic partial nephrectomy (LPN).Methods: The m-CI was measured by using computed tomography in 113 patients who underwent LPN between May 2003 and June 2014. The RFL following LPN was calculated by examining the estimated glomerular filtration rate (eGFR) and radioisotope renography one year postoperatively. The Pythagorean theorem was used to calculate the distance from the tumour ce

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19

Langleben, D., J. L. Szarek, J. T. Coflesky, R. C. Jones, L. M. Reid, and J. N. Evans. "Altered artery mechanics and structure in monocrotaline pulmonary hypertension." Journal of Applied Physiology 65, no. 5 (1988): 2326–31. http://dx.doi.org/10.1152/jappl.1988.65.5.2326.

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Pulmonary hypertension in rats, induced by an injection of monocrotaline, is associated with changes in the wall structure of the pulmonary arterial bed. We have studied the effects of this remodeling on mechanical properties of cylindrical pulmonary artery segments from rats 21 days after monocrotaline (MCT) injection. Resting and active (KCl induced) circumference-tension relationships were established for segments of extrapulmonary and intrapulmonary arteries isolated from the hilum and the fifth lateral branch from the axial pathway (all preacinar). The thicknesses of the vessel wall, the

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20

Conhaim, R. L., S. J. Lai-Fook, and N. C. Staub. "Sequence of perivascular liquid accumulation in liquid-inflated dog lung lobes." Journal of Applied Physiology 60, no. 2 (1986): 513–20. http://dx.doi.org/10.1152/jappl.1986.60.2.513.

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The peribronchovascular interstitium of the lung is a potential space that expands in pulmonary edema with the formation of large liquid cuffs. To study the time course of cuff formation we inflated nine isolated dog lung lobes with liquid to total lung capacity, rapidly froze them in liquid N2 after inflation periods of 1–300 min, then photographed 20 blocks of each lobe at X3 magnification. From the photographs we measured the ratio of cuff area to vessel area for arteries and veins of 0.05–8 mm diam. We found that the cuff-to-vessel area ratio attained a maximum value of 3–4, which was inde

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21

Chegai, F., A. U. Cavallo, M. Forcina, et al. "Giant Splenorenal Shunt in a Young Patient with Autoimmune Hepatitis/Primary Biliary Cholangitis Overlap Syndrome and Portal Vein Thrombosis." Case Reports in Radiology 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/2167364.

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We present a case of giant Splenorenal Shunt (SRS) associated with portal vein thrombosis in a 37-year-old woman with a twelve-year history of autoimmune hepatitis/primary biliary cholangitis overlap syndrome. At the moment of the CT examination laboratory tests showed creatinine 1.5 mg/dl, bilirubin 1.5 mg/dl, INR 3, and Na 145 mmol/l and the Model End-Stage Liver Disease score was 24. Extensive calcified thrombosis causing complete occlusion of the portal vein lumen and partially occluding the origin of the superior mesenteric vein was present and a small calcified thrombus in the Splenic Ve

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22

Bedini, Giacomo, Giorgia Bastianelli, Swathi Sirisha Nallan Chakravartula, et al. "Feasibility of FT-NIR spectroscopy and Vis/NIR hyperspectral imaging for sorting unsound chestnuts." Italus Hortus 27 (April 2020): 3–18. http://dx.doi.org/10.26353/j.itahort/2020.1.0318.

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Authors explored the potential use of Vis/NIR hyperspectral imaging (HSI) and Fourier-transform Near-Infrared (FT-NIR) spectroscopy to be used as in-line tools for the detection of unsound chestnut fruits (i.e. infected and/or infested) in comparison with the traditional sorting technique. For the intended purpose, a total of 720 raw fruits were collected from a local company. Chestnut fruits were preliminarily classified into sound (360 fruits) and unsound (360 fruits) batches using a proprietary floating system at the facility along with manual selection performed by expert workers. The two

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23

Friedrich, Ivar, Jan Spillner, Er-Xiong Lu, et al. "Induction of endotoxin tolerance improves lung function after warm ischemia in dogs." American Journal of Physiology-Lung Cellular and Molecular Physiology 284, no. 1 (2003): L224—L231. http://dx.doi.org/10.1152/ajplung.00138.2002.

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In shock models, induction of endotoxin tolerance (ET) is known to have a protective effect. The present study was designed to explore if ET is effective in protecting lungs from reperfusion injury. Twelve foxhounds were used as experimental animals. After a left thoracotomy, the left hilum was clamped for 3 h, followed by 8 h of reperfusion. In the treatment group (ET, n = 6), dogs were pretreated with incremental daily endotoxin doses of up to 60 μg/kg on day 6. The ischemia and reperfusion experiment was carried out on day 9. Control group animals ( n = 6) were not subjected to endotoxin. A

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24

Chen, Wenshu, Shijiang Yang, Wei Ping, Xiangning Fu, Qinzi Xu, and Jianing Wang. "CYP2J2 and EETs Protect Against Lung Ischemia/Reperfusion Injury via Anti-Inflammatory Effects in Vivo and in Vitro." Cellular Physiology and Biochemistry 35, no. 5 (2015): 2043–54. http://dx.doi.org/10.1159/000374011.

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Background: Injurious inflammatory response is critical to the development of lung ischemia/reperfusion injury (LIRI). The cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acid to epoxyeicosatrienoic acids (EETs), which exert an anti-inflammatory effect on the cardiovascular system. We therefore cytochrome hypothesized that CYP2J2 overexpression and pretreatment with exogenous EETs may have the potential to reduce LIRI. Methods: A rat model was used to mimic the condition of LIRI by clamping the left pulmonary hilum for 60 minutes, followed by reperfusion for 2 hours. Moreover,

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Nguyen, Thuan D., R. J. Lawn, and L. M. Bielig. "Expression and inheritance of perenniality and other qualitative traits in hybrids between mungbean cultivars and Australian wild accessions." Crop and Pasture Science 63, no. 7 (2012): 619. http://dx.doi.org/10.1071/cp12263.

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The expression and inheritance of several qualitative traits was examined in four cultivated × wild hybrid populations involving each of two mungbean (Vigna radiata ssp. radiata) cultivars, cvv. Berken and Kiloga, and each of two Australian accessions of the wild subspecies (V. radiata ssp. sublobata). One of the wild accessions, ACC 1, was representative of a prostrate, fine-stemmed, gracile type and the other, ACC 87, was representative of a more robust perennial form endemic in north-eastern Australia. For each of the four cultivated × wild populations, trait expression was observed in plan

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Sakuma, Tsutomu, Keiji Takahashi, Nobuo Ohya, et al. "Ischemia-reperfusion lung injury in rabbits: mechanisms of injury and protection." American Journal of Physiology-Lung Cellular and Molecular Physiology 276, no. 1 (1999): L137—L145. http://dx.doi.org/10.1152/ajplung.1999.276.1.l137.

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To study the mechanisms responsible for ischemia-reperfusion lung injury, we developed an anesthetized rabbit model in which the effects of lung deflation, lung inflation, alveolar gas composition, hypothermia, and neutrophils on reperfusion pulmonary edema could be studied. Rabbits were anesthetized and ventilated, and the left pulmonary hilum was clamped for either 2 or 4 h. Next, the left lung was reperfused and ventilated with 100% oxygen. As indexes of lung injury, we measured arterial oxygenation, extravascular lung water, and the influx of a vascular protein (131I-labeled albumin) into

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Franco-Acevedo, Adriana, Raquel Echavarria, Bibiana Moreno-Carranza, et al. "Opioid Preconditioning Modulates Repair Responses to Prevent Renal Ischemia-Reperfusion Injury." Pharmaceuticals 13, no. 11 (2020): 387. http://dx.doi.org/10.3390/ph13110387.

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Progression to renal damage by ischemia-reperfusion injury (IRI) is the result of the dysregulation of various tissue damage repair mechanisms. Anesthetic preconditioning with opioids has been shown to be beneficial in myocardial IRI models. Our main objective was to analyze the influence of pharmacological preconditioning with opioids in renal function and expression of molecules involved in tissue repair and angiogenesis. Experimental protocol includes male rats with 45 min ischemia occluding the left renal hilum followed by 24 h of reperfusion with or without 60 min preconditioning with mor

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28

Li, J., S. J. Lai-Fook, and R. L. Conhaim. "Effect of hyaluronidase on interstitial cuff and pressure response in liquid-inflated rabbit lung." Journal of Applied Physiology 72, no. 4 (1992): 1261–69. http://dx.doi.org/10.1152/jappl.1992.72.4.1261.

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The sequential pattern of perivascular interstitial cuff growth was studied in liquid-inflated rabbit lungs. Degassed isolated lungs were immersed in a saline bath and inflated to 5 cmH2O transpulmonary pressure with a 3% albumin solution or 3% albumin solution containing hyaluronidase. After inflation times varying between 1 and 7 h, the lungs were frozen in liquid N2. From blocks cut from the frozen lungs, interstitial cuff cross-sectional area was measured as a function of vessel size. No cuffs were observed around vessels less than 0.1 mm diam. At all inflation times, only approximately 50

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29

Briggs, B. A., T. M. Bradley, P. Vernon, et al. "Measurement of lung tissue mass, thoracic blood and interstitial volumes by transmission/emission scanning using [99mTc]pertechnetate." Clinical Science 73, no. 3 (1987): 319–27. http://dx.doi.org/10.1042/cs0730319.

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1. We have developed a method for non-invasive measurement of lung tissue mass, thoracic blood and interstitial volumes by a combination of transmission and emission scanning with technetium isotope (99mTc). 2. In a lung model we demonstrated that emission counts could be successfully corrected for attenuation with data obtained by transmission scanning, despite an uneven distribution of radioactivity and attenuation in the model. 3. In dogs we compared regional transthoracic tissue thickness, measured by transmission scanning, and regional ‘thickness’ of blood measured by transmission/emissio

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Moskowitzova, Kamila, Arzoo Orfany, Kaifeng Liu, et al. "Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury." American Journal of Physiology-Lung Cellular and Molecular Physiology 318, no. 1 (2020): L78—L88. http://dx.doi.org/10.1152/ajplung.00221.2019.

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The most common cause of acute lung injury is ischemia-reperfusion injury (IRI), during which mitochondrial damage occurs. We have previously demonstrated that mitochondrial transplantation is an efficacious therapy to replace or augment mitochondria damaged by IRI, allowing for enhanced muscle viability and function in cardiac tissue. Here, we investigate the efficacy of mitochondrial transplantation in a murine lung IRI model using male C57BL/6J mice. Transient ischemia was induced by applying a microvascular clamp on the left hilum for 2 h. Upon reperfusion mice received either vehicle or v

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Zabala, Gracia, Anupreet Kour, and Lila O. Vodkin. "Overexpression of an ethylene-forming ACC oxidase (ACO) gene precedes the Minute Hilum seed coat phenotype in Glycine max." BMC Genomics 21, no. 1 (2020). http://dx.doi.org/10.1186/s12864-020-07130-8.

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Abstract Background To elucidate features of seed development, we investigated the transcriptome of a soybean isoline from the germplasm collection that contained an introgressed allele known as minute hilum (mi) which confers a smaller hilum region where the seed attaches to the pod and also results in seed coat cracking surrounding the hilum region. Results RNAs were extracted from immature seed from an extended hilum region (i.e., the hilum and a small ring of tissue surrounding the hilum in which the cracks form) at three different developmental stages:10–25, 25–50 and 50–100 mg seed fresh

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Mogawer, Mohamad Sherif, Sahar Abdel Rahman Nassef, Samah Mohamad Abd Elhamid, et al. "Role of renal Duplex ultrasonography in evaluation of hepatorenal syndrome." Egyptian Liver Journal 11, no. 1 (2021). http://dx.doi.org/10.1186/s43066-021-00104-9.

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Abstract Background Hepatorenal syndrome is a potentially fatal complication of advanced liver disease. Markers for early diagnosis and identification of high-risk patients are lacking. Our aim was to evaluate the role of renal Duplex ultrasonography in the diagnosis and early prediction of hepatorenal syndrome. This study included 50 patients. Clinical assessment, liver function tests, hepatitis C virus antibody, kidney function tests, and abdominal and renal color Duplex ultrasound were done to all subjects. Results Univariate regression analysis for hepatorenal syndrome showed a statistical

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Lerner, Andrew D., and David Feller-Kopman. "Disorders of the Pleura, Mediastinum, and Hilum." DeckerMed Medicine, July 24, 2019. http://dx.doi.org/10.2310/im.1199.

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The pleura are a composition of two serous membranes: the visceral pleura lining the lungs and the parietal pleura lining the inner chest wall, diaphragm, and mediastinum. The pulmonary hilum is composed of blood vessels, airways, nerves, and lymph nodes and denotes the meeting point between the mediastinum and the pleural cavities. This review covers disorders of the pleura, mediastinum, and hilum. Figures show a schematic diagram of normal filtration/resorption of fluid in the pleural space; comparison of a simultaneously obtained chest x-ray (CXR) and a chest computed tomographic (CT) scan

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Lerner, Andrew D., and David Feller-Kopman. "Disorders of the Pleura, Mediastinum, and Hilum." DeckerMed Family Medicine, July 24, 2019. http://dx.doi.org/10.2310/fm.1199.

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The pleura are a composition of two serous membranes: the visceral pleura lining the lungs and the parietal pleura lining the inner chest wall, diaphragm, and mediastinum. The pulmonary hilum is composed of blood vessels, airways, nerves, and lymph nodes and denotes the meeting point between the mediastinum and the pleural cavities. This review covers disorders of the pleura, mediastinum, and hilum. Figures show a schematic diagram of normal filtration/resorption of fluid in the pleural space; comparison of a simultaneously obtained chest x-ray (CXR) and a chest computed tomographic (CT) scan

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Burnette, Dylan T., Aidan Fenix, Nilay Taneja, et al. "Abstract 390: Actin Arcs are Essential Templates for Sarcomere Assembly in Cardiomyocytes." Circulation Research 121, suppl_1 (2017). http://dx.doi.org/10.1161/res.121.suppl_1.390.

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The sarcomere is the basic contractile unit within cardiomyocytes. The proper assembly of sarcomeres during development and their maintenance during homeostasis are critical for the contraction of the heart. How molecular components of sarcomeres assemble remains a major unanswered question. Here we use newly plated h uman i nduced pluripotent stem cell-derived c ardio m yocytes (hiCM) combined with high-resolution microscopy to elucidate the steps of de novo sarcomere assembly. We found that sarcomere formation was preceded by bundles of actin filaments resembling the so-called “actin arcs” p

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Guberina, Maja, Kaid Darwiche, Hubertus Hautzel, et al. "Patterns of nodal spread in stage III NSCLC: importance of EBUS-TBNA and 18F-FDG PET/CT for radiotherapy target volume definition." Radiation Oncology 16, no. 1 (2021). http://dx.doi.org/10.1186/s13014-021-01904-4.

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Abstract Purpose The aim of this study was to compare the pattern of intra-patient spread of lymph-node (LN)-metastases within the mediastinum as assessed by 18F-FDG PET/CT and systematic endobronchial ultrasound-guided transbronchial-needle aspiration (EBUS-TBNA) for precise target volume definition in stage III NSCLC. Methods This is a single-center study based on our preceding investigation, including all consecutive patients with initial diagnosis of stage IIIA-C NSCLC, receiving concurrent radiochemotherapy (12/2011–06/2018). Inclusion criteria were curative treatment intent, 18F-FDG PET/

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Selim, Jean, Mouad Hamzaoui, Inès Boukhalfa, et al. "Cardiopulmonary bypass increases endothelial dysfunction after pulmonary ischaemia-reperfusion in an animal model." European Journal of Cardio-Thoracic Surgery, December 4, 2020. http://dx.doi.org/10.1093/ejcts/ezaa412.

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Abstract OBJECTIVES Endothelial dysfunction during ischaemia-reperfusion (IR) is a major cause of primary graft dysfunction during lung transplantation. The routine use of cardiopulmonary bypass (CPB) during lung transplantation remains controversial. However, the contribution of CPB to pulmonary endothelial dysfunction remains unclear. The objective was to investigate the impact of CPB on endothelial dysfunction in a lung IR rat model. METHODS Rats were allocated to 4 groups: (i) Sham, (ii) IR, (iii) CPB and (iv) IR-CPB. The primary outcome was the study of pulmonary vascular reactivity by wi

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Song, Qingling, Yanyan Yu, Xiaomiao Zhang, et al. "Value of MRI and diffusion weighted imaging in diagnosing normal-sized pelvic lymph nodes metastases in patients with cervical cancer." British Journal of Radiology, October 23, 2020, 20200203. http://dx.doi.org/10.1259/bjr.20200203.

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Objectives: To investigate the value of conventional magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) in diagnosing normal-sized pelvic lymph nodes metastases in patients with cervical cancer. Methods: 102 patients with cervical cancer who underwent MRI and DWI scan were included. 137 lymph nodes were analyzed, including 44 metastatic lymph nodes(MLNs) and 93 non-metastatic lymph nodes(non-MLNs).The morphology and apparent diffusion coefficient (ADC) value of lymph nodes were measured including short-axis diameter (DS), long-axis diameter (DL), ratio of short to long-axis

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Zhou, Yang, Yawen Tang, Lianzhong Zhao, Rui Lu, and Jianyi Zhang. "Abstract 442: Epigenetic Regulation of Ezh2 in Direct Human Cardiac Reprogramming." Circulation Research 127, Suppl_1 (2020). http://dx.doi.org/10.1161/res.127.suppl_1.442.

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Cardiovascular disease is still the leading cause of death in the United States. Due to the limited regenerative capacity of adult hearts, the damage caused by heart injury could not be reversed and often progressed into heart failure. In need of cardiovascular disease treatment, many therapies aimed at either cell transplantation or cell regeneration have been proposed. Direct reprogramming of somatic cells into induced cardiomyocytes (iCMs) is considered to be a promising strategy for regenerative medicine. The induction of cardiomyocytes from non-myocytes has been achieved efficiently via e

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Czembor, Elzbieta, Jerzy H. Czembor, Radoslaw Suchecki, and Nathan S. Watson-Haigh. "DArT-based evaluation of soybean germplasm from Polish Gene Bank." BMC Research Notes 14, no. 1 (2021). http://dx.doi.org/10.1186/s13104-021-05750-1.

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Abstract Objective Soybean is an important plant used for food, feed and many industrial purposes. Interest in soybean breeding is growing in Central Europe, including Poland. A very large number of soybean accessions are stored in gene banks, but less than 1% of them have been used for breeding. Here, we present genotypic data as well as phenotypic data on plant and seed performance, including seed chlorophyll fluorescence traits, and on yield components within a collection of soybean accessions that are conserved in the Polish Gene Bank at the Plant Breeding and Acclimatization Institute-Nat

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F. Levy, Marlon, Daisuke Imai, Vinay Kumaran, et al. "Utilization of a Reduced Graft from a Severely Traumatized Liver: A Case Report and Strategy to Increase Availability of Livers for Transplant." Surgical Case Reports, April 30, 2021, 1–4. http://dx.doi.org/10.31487/j.scr.2021.04.09.

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Background: Trauma victims with liver lacerations in the hilum are typically excluded from liver donation. We report a case of a successful liver transplant from a deceased donor with a grade 4 hilar liver laceration. Case Presentation: We used a liver with a high-grade laceration from a 28-year-old brain-dead traffic accident victim. The liver had grade IV lacerations in the right and caudate lobes. In situ split liver technique was applied to control the lacerations after an intraoperative cholangiogram revealed favourable anatomy. The left hemi-liver graft was procured, retaining the entire

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Kawachi, Shigeyuki, Naokazu Chiba, Masashi Nakagawa, et al. "Living donor liver transplantation for idiopathic portal hypertension with extrahepatic portal vein stenosis and splenic artery aneurysms: a case report and review of the literature." BMC Surgery 20, no. 1 (2020). http://dx.doi.org/10.1186/s12893-020-00921-6.

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Abstract Background Idiopathic portal hypertension (IPH) generally has a good prognosis and rarely results in liver transplantation. Furthermore, there are few reports of living donor liver transplantation (LDLT) for IPH with extrahepatic portal vein stenosis. Case presentation We report the case of a 51-year-old female patient diagnosed with IPH more than 20 years ago. She suffered severe jaundice, massive ascites, and encephalopathy at the time of her visit to our hospital. The patient’s extrahepatic portal vein showed a scar-like stenosis, and the portal flow was completely hepatofugal. Col

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Maghfur, Ifdlolul. "Peran Politik Ekonomi Islam dalam Melaksanakan Globalisasi Masyarakat Ekonomi Asean (MEA)." JURNAL HUKUM ISLAM, February 10, 2017, 27. http://dx.doi.org/10.28918/jhi.v0i0.744.

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Penelitian ini membahas tentang peran, pengaruh, dan kemanfaatan politik ekonomi Islam dalam melaksanakan Masyarakat Ekonomi ASEAN (MEA) di Indonesia. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Dalam menggali data, peneliti berusaha untuk mengetahui fakta terhadap data yang terkumpul dari hasil penelitian untuk selanjutnya diolah dan dianalisis. Pola berpikir yang peneliti gunakan adalah dengan pola induktif, yakni menggambarkan konsep politik ekonomi Islam secara khusus (dalil teori), lalu dikorelasikan dengan kasus yang terjadi secara umum, yaitu ekonomi ASEAN, dengan maksu

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Du, Li-Wen, Hong-Li Liu, Hai-Yan Gong, et al. "Adding contrast-enhanced ultrasound markers to conventional axillary ultrasound improves specificity for predicting axillary lymph node metastasis in patients with breast cancer." British Journal of Radiology, December 22, 2020, 20200874. http://dx.doi.org/10.1259/bjr.20200874.

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Objective: To evaluate the diagnostic performance of contrast-enhanced ultrasound (CEUS) combined with conventional ultrasound of axillary lymph nodes (ALNs) in predicting metastatic ALNs in patients with breast cancer. Methods: This retrospective study included 259 patients with breast cancer who underwent conventional ultrasound and CEUS. The parameters and patterns evaluated on conventional ultrasound included short axis diameter (S), long axis/short axis (L/S) ratio, cortical thickness, resistive index (RI), lymph node (LN) morphology of greyscale ultrasound, hilum and vascular pattern. Me

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