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1

Anderson, James W., and Nancy J. Gustafson. "High-carbohydrate, high-fiber diet." Postgraduate Medicine 82, no. 4 (September 15, 1987): 40–55. http://dx.doi.org/10.1080/00325481.1987.11699970.

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Anderson, James W., Belinda Maness Smith, and Patti Bazel Geil. "High-fiber diet for diabetes." Postgraduate Medicine 88, no. 2 (August 1990): 157–68. http://dx.doi.org/10.1080/00325481.1990.11704705.

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3

Hines, P. J. "MICROBIOLOGY: A High-Fiber Diet." Science 316, no. 5822 (April 13, 2007): 175b. http://dx.doi.org/10.1126/science.316.5822.175b.

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Pal, Mahendra. "Growing Significance of High Fiber Diet in the Prevention of Some Chronic Diseases." Nutrition and Food Processing 5, no. 2 (April 26, 2022): 01–05. http://dx.doi.org/10.31579/2637-8914/082.

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The unhealthy lifestyle can result in the development of chronic diseases, and the bad lifestyle affects the gastrointestinal tract, cardiovascular system or other organ systems. Chronic diseases have been encountered throughout the world. The healthy eating (70%), and exercise (30%) are the part of a proper lifestyle. The daily intake fiber is recommended as part of a healthy diet. Consuming a varied high-fiber diet means that one is getting ample of vegetables, fruits, legumes, and whole grains. Fibers are indigestible plant polysaccharides that can be water-soluble or water-insoluble. The oats and barley are good sources of water-soluble fiber whereas whole-meal grains and whole-meal breads are significant sources of water-insoluble fiber. Cereals, fruits, and vegetables are important sources of fibers. A high fiber diet contains about 40 grams of fiber and it can reduce the development of chronic diseases, such as tumors, intestinal complaints, metabolic disorders (high cholesterol level, diabetes, and obesity), and cardiovascular problems. In addition, fiber supplementation can be used as part of nutrition therapy. The manuscript focuses on the characteristics of a high fiber diet. It is hoped that our manuscript will contribute to the expansion of knowledge in the scientific society, and also provide advice to protect their health.
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Ferrarelli, Leslie K. "Why a High-Fiber Diet Prevents Cancer." Science Signaling 8, no. 359 (January 13, 2015): ec8-ec8. http://dx.doi.org/10.1126/scisignal.aaa6561.

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TUCKER, MIRIAM E. "High-Fiber Diet Delivers Preeclampsia Risk Reduction." Family Practice News 35, no. 3 (February 2005): 57. http://dx.doi.org/10.1016/s0300-7073(05)71343-8.

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7

Jin, Shunshun, Changning Yu, Haoxiang Xu, Paula Azevedo, Huaigang Lei, Argenis Rodas, Martin Nyachoti, Karmin O, and Chengbo Yang. "161 Effect of High- and low-Fiber Diets on Growth Performance in Growing-Finishing Pigs Selected for low or High Feed Efficiency." Journal of Animal Science 100, Supplement_3 (September 21, 2022): 75. http://dx.doi.org/10.1093/jas/skac247.147.

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Abstract Understanding the effects of high- and low-fiber diets on the growth performance of pigs with different feed efficiencies will help the livestock industry develop new strategies to reduce the costs of pig production. In this study, 18 Landrace × Large White sows with high and low estimated breeding value on feed conversion ratio (EBV-FCR) were inseminated with semen from Large White with known EBV-FCR to produce 9 litters of low feed efficiency pigs and 9 litters of high feed efficiency pigs. A total of 94 growing pigs with low or high feed efficiency were fed a low-fiber (3% crude fiber) or high-fiber (6% crude fiber) content diet in a 2 × 2 factorial arrangement for 70 days. Pigs fed a high-fiber diet presented higher body weight (BW) on day 70 (P < 0.05). High feed efficiency pigs presented lower average daily feed intake (ADFI) and feed conversion ratio (FCR) than low feed efficiency pigs from day 0 to 70 (P< 0.05). There was an interaction between fiber and feed efficiency group on average daily gain (ADG;P < 0.05) and FCR (P < 0.05) from day 0 to 35. High feed efficiency pigs fed a high-fiber diet presented lower FCR than low feed efficiency pigs fed a low-fiber diet (P< 0.05). Low feed efficiency pigs fed a low-fiber diet showed the lowest ADG (P< 0.05). Regardless of efficiency groups, pigs fed a high-fiber diet presented higher ADG and lower FCR than pigs fed a low-fiber diet from day 42 to 70 (P< 0.05). These results suggest that high feed efficiency pigs can present lower FCR and ADFI without reducing final BW and ADG. Feeding a high-fiber diet can increase ADG and reduce FCR in the later stages of the experiment.
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8

Williams, Christine L., and Marguerite Bollella. "Is a High-fiber Diet Safe for Children?" Pediatrics 96, no. 5 (November 1, 1995): 1014–19. http://dx.doi.org/10.1542/peds.96.5.1014.

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Objectives: Although dietary fiber is associated with important health benefits in childhood, there have been concerns that very high fiber diets may result in adverse health effects. This report reviews the major safety concerns associated with consumption of very high fiber diets, estimates the amount of fiber that may cause adverse physiologic effects in children, and proposes safe levels of dietary fiber intake for children and adolescents. Methods. Published studies on dietary fiber intake in childhood were reviewed to determine major safety concerns, to document adverse effects, to characterize subjects involved and the dose and type of fiber consumed, and to estimate potential relevance to US children and adolescents. Levels of dietary fiber reported to have adverse health effects were compared with recommended levels of fiber intake for children older than 2 years of age. Results and Conclusions. A review of the scientific literature suggests that a small loss of energy, protein, and fat may occur with a high intake of dietary fiber. However, this small loss of energy is unlikely to be significant to children consuming adequate levels of major nutrients, especially at conservative fiber intakes as recommended by the American Health Foundation's age plus 5 formula. In addition, it is estimated that even with a doubling of current dietary fiber, there is unlikely to be an adverse effect on serum vitamin and mineral concentrations in healthy US children consuming a balanced diet containing adequate levels of nutrients. Thus, evidence suggests that for US children, a moderate increase in dietary fiber is more likely to be healthful than harmful.
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9

Gao, Wen-rong, Zheng-kun Wang, and Wan-long Zhu. "Plasticity in the physiological energetics of Apodemus chevrieri: the role of dietary fiber content." Animal Biology 66, no. 3-4 (2016): 259–77. http://dx.doi.org/10.1163/15707563-00002503.

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Small mammals are usually adapted to cope with changes in food quality and availability. In order to investigate the adaptive strategy of small rodents responding to varying dietary fiber content, in the present study,Apodemus chevrieriindividuals were acclimated to a high-fiber diet for four weeks and then a relatively low-fiber diet for another four weeks. The results show that body mass was relatively stable over the course of acclimation, but dry matter intake, gross energy intake and the mass of the digestive tract increased significantly and digestibility decreased significantly in high-fiber diet mice, while the digestible energy intake was similar for both high-fiber and low-fiber diet mice except for the first week. High-fiber/low-fiber diet mice showed only a significant lower basal metabolic rate and nonshivering thermogenesis compared to low-fiber diet mice on day R1. The high-fiber diet induced a decrease in serum leptin levels and brown adipose tissue mass associated with a reduction in the cytochromecoxidase activity and uncoupling protein 1 content of brown adipose tissue. Body mass, thermogenic capacity, energy intake, serum leptin levels and digestive tract morphology returned to the control levels after 4 weeks of refeeding low-fiber diet. Further, serum leptin levels were positively related to body fat mass and negatively related to food intake. These data indicated that body mass, energy intake, serum leptin levels and organ morphological plasticity were the main strategies by whichA. chevriericopes with variations in dietary fiber content.
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10

King, Dana E. "Effect of a High-Fiber Diet vs a Fiber-Supplemented Diet on C-Reactive Protein Level." Archives of Internal Medicine 167, no. 5 (March 12, 2007): 502. http://dx.doi.org/10.1001/archinte.167.5.502.

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11

Toh, Huishi, James A. Thomson, and Peng Jiang. "Maternal High-Fiber Diet Protects Offspring against Type 2 Diabetes." Nutrients 13, no. 1 (December 30, 2020): 94. http://dx.doi.org/10.3390/nu13010094.

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Previous studies have reported that maternal malnutrition is linked to increased risk of developing type 2 diabetes in adulthood. Although several diabetic risk factors associated with early-life environment have been identified, protective factors remain elusive. Here, we conducted a longitudinal study with 671 Nile rats whereby we examined the interplay between early-life environment (maternal diet) and later-life environment (offspring diet) using opposing diets that induce or prevent diet-induced diabetes. Specifically, we modulated the early-life environment throughout oogenesis, pregnancy, and nursing by feeding Nile rat dams a lifelong high-fiber diet to investigate whether the offspring are protected from type 2 diabetes. We found that exposure to a high-fiber maternal diet prior to weaning significantly lowered the risk of diet-induced diabetes in the offspring. Interestingly, offspring consuming a high-fiber diet after weaning did not develop diet-induced diabetes, even when exposed to a diabetogenic maternal diet. Here, we provide the first evidence that the protective effect of a high-fiber diet can be transmitted to the offspring through the maternal diet, which has important implications in diabetes prevention.
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12

Shahin, K. A., and F. Abd Elazeem. "Effects of breed, sex and diet and their interactions on carcass composition and tissue weight distribution of broiler chickens." Archives Animal Breeding 48, no. 6 (October 10, 2005): 612–26. http://dx.doi.org/10.5194/aab-48-612-2005.

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Abstract. The effects of breed (Hubbard and Anak), sex and diet (two levels of protein (high or low) with two levels of crude fiber (low or high) at each level of protein) on carcass composition and distribution of tissues over the carcass were studied. Carcass composition and ratios of muscle: bone, muscle: fat and meat: bone in the carcass did not differ significantly between breed groups. Male carcasses had more muscle, more bone, more fat-free carcass, higher ratios of muscle: bone, muscle: fat but less fat, less meat and lower meat: bone ratio than female carcasses. Carcasses of chicks fed high protein (with either low or high fiber) diet had more muscle than carcasses of chicks fed low protein (with either low or high fiber) diet. Carcasses of chicks fed high fiber (with either low or high protein) diet had more bone but less meat than carcasses of chicks fed low fiber (with either low or high protein) diet. Increasing both protein and fiber in the diet resulted in lowering carcass fat, consequently raising muscle: fat ratio. Breed and sex did not influence the distribution of muscle and meat throughout the carcass parts. Breed differences in fat weight distribution were not significant. Anak had significantly higher proportions of bone in wing and neck than Hubbard did. The proportion of total carcass muscle in breast, drumstick, wing were not significantly affected by diet. Carcasses of chicks fed high fiber (with either low or high protein) diet had higher proportion of total meat in thigh and neck than carcasses from chicks fed low fiber (with either low or high protein) diet. Diet had no significant effect on bone weight distribution. Increasing crude fiber in diets resulted in lowering proportion of total fat in breast, thigh but increasing proportion of total fat in drumstick and wing. Breed x sex, breed x diet and sex x diet interactions did not significantly influence most of carcass traits indicating that the factors under consideration act independently of each other's. Significant sex x diet interactions was found for carcass fat and boneless carcass relative to live body weight: the sexual dimorphism in low protein diet is more pronounced than in high protein diets.
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13

STEWART, DONNA E., and D. Psych. "High-Fiber Diet and Serum Tricyclic Antidepressant Levels." Journal of Clinical Psychopharmacology 12, no. 6 (December 1992): 438. http://dx.doi.org/10.1097/00004714-199212000-00010.

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14

Wiedmeier, R. W., J. J. Villalba, A. Summers, and F. D. Provenza. "Eating a high fiber diet during pregnancy increases intake and digestibility of a high fiber diet by offspring in cattle." Animal Feed Science and Technology 177, no. 3-4 (November 2012): 144–51. http://dx.doi.org/10.1016/j.anifeedsci.2012.08.006.

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15

Mallepula, Bhavana. "Development of HIGH FIBER NUTRIRICH MUFFIN to combat malnutrition." Research International Journal of Food and Nutrition 01, no. 01 (April 18, 2024): 001–3. http://dx.doi.org/10.37179/rijfn.000001.

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These days people have gotten accustomed to completely relying upon processed food to fulfi ll their daily energy requirements. As time evolved many healthy foods like millets were left behind by the modern generation and convenience foods were adopted. These lifestyle changes made them suff er from lots of disorders over time. This new product is a small trial to re-introduce those nutrient-rich but abandoned foods into the daily diet in a modernized way. A Few of the nutritive but rejected foods like millet, apple peel extract, and defatted soybean fl our were selected and made into a pie so that people could consume it with ease.Keywords: Benthic Organisms, Peninsular Malaysia, Coastal Ecosystem.
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16

Anderson, James W., and Nancyj Gustafson. "Adherence to High-Carbohydrate, High-Fiber Diets." Diabetes Educator 15, no. 5 (October 1989): 429–34. http://dx.doi.org/10.1177/014572178901500512.

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Successful diabetes management demands a high degree of adherence. Adherence to medical prescriptions, particularly special diets, is notoriously poor. A study of 40 individuals with IDDM and NIDDM who were followed an average of 23 months found good or excellent dietary adherence in 70 % of subjects; only 5 % demon strated poor adherence. Adherence was assessed objec tively based on carbohydrate, fat, and fiber intakes reported in 24- hour food recalls, 7-day food frequency surveys, and home food records. High dietary fiber intake may independently enhance adherence, perhaps by increasing satiety or because of the simplicity of the concept. Good communi cation between the health profes sional and patient is also fundamental to all stages of dietary adherence. Use of adherence-enhancing techniques throughout adoption of new diet behaviors promotes long-term adherence to high-carbohydrate, high-fiber diets.
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Abdulkreem, Ghenaa Hamid, Feryal Farouk Al-Azzawi, and Noor Jumhaa Fadhil. "Health Effects of Diets (High-Fiber Diet and Intermittent Fasting) on Experimental Animals." International Journal of Agriculture and Animal Production, no. 36 (October 1, 2023): 17–30. http://dx.doi.org/10.55529/ijaap.36.17.30.

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The study was conducted on 24 males of sexually mature white mice at the age of 7-8 weeks and weighing 20-30 ± 2 g, four treatments were used in this study, where 6 mice were isolated for first treatment (without any treatment), mice in the second group were fattened with animal fat by 30% until the end of the experiment for a period of (40) days, while the third and fourth groups were fattened in the same way as the second group for a period of 10 days, then the third group was treated with the fasting system, and the fourth group was treated with the fiber system for a month. This study aimed to determine the effect of treatment with a fasting regimen and fiber regimen on body weight and to know the effect on Intestinal tissue bioavailability. The results showed that there is a significant decrease in weight after fasting and after eating fiber (±2.57, ±3.29) respectively, compared to treatment after fattening (±3.81). It is clear from the results of the current study that fasting and fiber have a positive effect on weight reduction in male mice and intestinal bioavailability.
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Abdulkreem, Ghenaa Hamid, Feryal Farouk Al-Azzawi, and Noor Jumhaa Fadhil. "Health Effects of Diets (High-Fiber Diet and Intermittent Fasting) on Experimental Animals." International Journal of Agriculture and Animal Production, no. 36 (October 1, 2023): 18–31. http://dx.doi.org/10.55529/ijaap.36.18.31.

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The study was conducted on 24 males of sexually mature white mice at the age of 7-8 weeks and weighing 20-30 ± 2 g, four treatments were used in this study, where 6 mice were isolated for first treatment (without any treatment), mice in the second group were fattened with animal fat by 30% until the end of the experiment for a period of (40) days, while the third and fourth groups were fattened in the same way as the second group for a period of 10 days, then the third group was treated with the fasting system, and the fourth group was treated with the fiber system for a month. This study aimed to determine the effect of treatment with a fasting regimen and fiber regimen on body weight and to know the effect on Intestinal tissue bioavailability. The results showed that there is a significant decrease in weight after fasting and after eating fiber (±2.57, ±3.29) respectively, compared to treatment after fattening (±3.81). It is clear from the results of the current study that fasting and fiber have a positive effect on weight reduction in male mice and intestinal bioavailability.
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Yang, Jae-Kyung, Myung-Suk Choi, Chang-Joon Kim, Yong-Seung Shin, Dae-Yong Han, Sang-Woo Han, Bu-Kug Lim, et al. "Physiological Function of Insoluble Dietary Fiber Prepared from Exploded Oak Wood (Quercus mongolica)." American Journal of Chinese Medicine 34, no. 01 (January 2006): 87–97. http://dx.doi.org/10.1142/s0192415x06003667.

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This study investigated the production of insoluble dietary fiber using exploded and chemically treated oak wood (Quercus mongolica) and the physiological functions of prepared insoluble dietary fiber in laboratory animals. To produce high quality insoluble dietary fiber, the steam explosion treatment was performed at 25 kg f/ cm 2 pressure for 6 minutes. In the chemical analysis of insoluble dietary fiber, exploded oak wood was pretreated by 1% sodium hydroxide solution. The insoluble dietary fiber contained 7.6% residual lignin and 61.7% of α-cellulose. In order to compare the physiological functions of prepared insoluble dietary fiber with those of commercial insoluble dietary fiber, Sprague-Dawley male rats weighing 100 ± 10 g were randomly assigned to one normal diet and five high cholesterol diets, containing 1% cholesterol. The high cholesterol diet groups were classified as the fiber-free diet (FF group), 5% commercial α-cellulose diet group (5C group), 10% commercial α-cellulose group (10C group), 5% insoluble dietary fiber group (5M group) and 10% insoluble dietary fiber group (10M group). Food intake, weight gain and food efficiency ratio in high cholesterol groups were significantly higher than those of the normal group, but there were no significant differences among the high cholesterol diet groups. In addition, there were no significant differences in the weights of liver, kidney and small intestine in insoluble dietary fiber-supplemented groups. Cecum weights in all insoluble dietary fiber groups were significantly higher than those of the FF group. There were no significant differences in the activities of the glutamic pyruvic transaminase (GPT) and glutamic oxaloacetic transaminase (GOT) among the insoluble dietary fiber-supplemented groups. In conclusion, the prepared insoluble dietary fiber and the commercially available insoluble fiber showed the same physiological effects. Moreover, the preparation method for the insoluble dietary fiber from the exploded oak wood was successful.
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Hermawan, D., Sunarti ., and P. Hastuti. "High Fiber Diet Decreases the Level of Interleukin 1." KnE Life Sciences 4, no. 12 (March 25, 2019): 30. http://dx.doi.org/10.18502/kls.v4i12.4154.

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21

Rosenberg, Karen, and Subhashni D. Singh Joy. "A High-Fiber Diet may be Associated with Diverticulosis." AJN, American Journal of Nursing 112, no. 6 (June 2012): 53. http://dx.doi.org/10.1097/01.naj.0000415130.94014.88.

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Printz, Carrie. "High fiber diet prevents prostate cancer progression in mice." Cancer 119, no. 13 (June 17, 2013): 2361. http://dx.doi.org/10.1002/cncr.28207.

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Rubin, Rita. "High-Fiber Diet Might Protect Against Range of Conditions." JAMA 321, no. 17 (May 7, 2019): 1653. http://dx.doi.org/10.1001/jama.2019.2539.

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24

Bestari, S. A., F. Fulyani, R. J. Kusuma, and E. S. Lestari. "A diet high in protein and fiber changes the gut microbiota of colorectal cancer rat model." Food Research 7, no. 3 (June 30, 2023): 221–26. http://dx.doi.org/10.26656/fr.2017.7(3).575.

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Emerging evidence has suggested that gut microbiota dysbiosis may have a role in colorectal cancer (CRC) progression. Dietary intake high in plant protein and fiber has been associated with reduced risk of this cancer through modulation of gut microbiota. This study aimed to evaluate the effect of the soy protein and fiber diet on gut Lactobacillus and Bifidobacterium of azoxymethane/dextran sodium sulfate (AOM/DSS)- induced rat. A total of twenty-five Wistar rats aged eight weeks were randomly assigned into five groups: the normal control group (NC), the AOM/DSS group, the high protein diet +AOM/DSS group (HP), the high fiber diet +AOM/DSS group (HF), and the combination soy protein and fiber diet+ AOM/DSS group (PF). CRC was induced by injecting 12 mg/kg BW per week of AOM and adding 2% DSS into the drinking water. After four weeks, the rats were sacrificed, and the total DNA was isolated from the cecum. The relative abundance of Lactobacillus and Bifidobacterium was analyzed using quantitative real-time PCR. The fecal cecum samples analysis demonstrated that rats receiving a high soy protein diet (HP), high fiber diet (HF), or both diets (PF) have significantly higher Lactobacillus count compared with the AOM/DSS group that only received a standard diet. In the case of Bifidobacterium, both HP and PF diets showed higher abundance relative to AOM/DSS group, though it was not significant. In conclusion, dietary intake consisting of high soy protein, fiber, or a combination of the two diets modulates the gut microbiota of AOM/DSS-treated rats.
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Malik, Neal, Serena Tonstad, and Ella Haddad. "Beyond “Counting Macros”: Are Common Fad Diets Nutritionally Adequate? An Examination of Their Micronutrient Content." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 1823. http://dx.doi.org/10.1093/cdn/nzaa067_050.

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Abstract Objectives We compared a high-fiber bean-rich diet with a low-carbohydrate diet in a randomized controlled trial to assess their effects on body weight, blood lipids and micronutrient adequacy. Methods One hundred and seventy-three women and men with a mean body mass index of approximately 36 kg · m−2 were randomized to a high-fiber bean-rich diet that achieved mean (SD) fiber intakes of 35.5 (18.6) g · day−1 for women and 42.5 (30.3) g · day−1 for men, or a low-carbohydrate diet (<120 g · day−1). Both diets were induced gradually over 4 weeks and included a 3-day feeding phase. Results After 52 weeks, the low-carbohydrate (n = 24) group tended to retain weight loss better than the high-fiber group (n = 30) (P = 0.06), although total cholesterol remained lower with the bean-rich diet (P = 0.049). The low-carbohydrate group consumed more vitamin K (P = 0.006), thiamin (P = 0.001), and niacin (P = 0.02) whereas those in the high-fiber group consumed more folate (P = 0.006), magnesium (P = 0.046) and copper (P = 0.017). Both groups consumed less than the RDA for vitamin D, vitamin E, calcium, magnesium and copper. Conclusions A high-fiber bean-rich diet was as effective as a low-carbohydrate diet for weight loss. However, both diets were deficient in micronutrients. These results may have implications for long-term disease risk and morbidity management. Funding Sources Lifestyle Center of America (Sulphur, OK).
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Patel, Piyush, Dilip Kumar Malipatlolla, Sravani Devarakonda, Cecilia Bull, Ana Rascón, Margareta Nyman, Andrea Stringer, Valentina Tremaroli, Gunnar Steineck, and Fei Sjöberg. "Dietary Oat Bran Reduces Systemic Inflammation in Mice Subjected to Pelvic Irradiation." Nutrients 12, no. 8 (July 22, 2020): 2172. http://dx.doi.org/10.3390/nu12082172.

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Patients undergoing radiotherapy to treat pelvic-organ cancer are commonly advised to follow a restricted fiber diet. However, reducing dietary fiber may promote gastrointestinal inflammation, eventually leading to deteriorated intestinal health. The goal of this study was to evaluate the influence of dietary fiber on radiation-induced inflammation. C57BL/6J male mice were fed a High-oat bran diet (15% fiber) or a No-fiber diet (0% fiber) and were either irradiated (32 Gy delivered in four fractions) to the colorectal region or only sedated (controls). The dietary intervention started at 2 weeks before irradiation and lasted for 1, 6, and 18 weeks after irradiation, at which time points mice were sacrificed and their serum samples were assayed for 23 cytokines and chemokines. Our analyses show that irradiation increased the serum cytokine levels at all the time points analyzed. The No-fiber irradiated mice had significantly higher levels of pro-inflammatory cytokines than the High-oat irradiated mice at all time points. The results indicate that a fiber-rich oat bran diet reduces the intensity of radiation-induced inflammation, both at an early and late stage. Based on the results, it seems that the advice to follow a low-fiber diet during radiotherapy may increase the risk of decreased intestinal health in cancer survivors.
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Yang, Junyi, and Devin J. Rose. "The impact of long-term dietary pattern of fecal donor on in vitro fecal fermentation properties of inulin." Food & Function 7, no. 4 (2016): 1805–13. http://dx.doi.org/10.1039/c5fo00987a.

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A diet high in whole grains, dry beans, and certain vegetables that contributed dietary fiber, plant protein, and B vitamins resulted in high short chain fatty acids, while a diet high in diary and processed meats that provided cholesterol and little fiber resulted in high branched chain fatty acids and ammonia during fecal fermentation of inulin.
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Nurmeiliasari, Nurmeiliasari, R. Priyanto, D. A. Astuti, Salundik, and J. Takahashi. "Utilization of Rumen Mechanical Stimulator as Pseudo Fiber in Ruminant to Minimize Metabolic Problem." Indonesian Bulletin of Animal and Veterinary Sciences 27, no. 2 (January 8, 2018): 67. http://dx.doi.org/10.14334/wartazoa.v27i2.1589.

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Feeding high concentrate diet, characterized with high starch and low fiber is applied to increase energy intake for an optimal production performance in ruminants. However, the prevalence of digestive disorder namely ruminal acidosis has been reported as drawback of this feeding strategy. This encourages farmers and nutritionist to supply adequate fiber in the diet to meet minimum dietary fiber requirement. However, feeding high forage diet is reported to give adverse effect on production performance, thus economic loss for farmers. Therefore, some sorts of artificial fiber utilizations have been introduced to reduce the risk of nutritional diseases as well as improving ruminant productivity. The utilization of rumen mechanical stimulator aims to maintain a healthy rumen function in ruminants fed with high concentrate diet. Objective of this article is to review recent development of rumen mechanical stimulators utilization, a pseudo fiber to substitute forage physical function in the rumen of ruminants. This review highlights the use of rumen mechanical stimulators in dairy cattle, beef cattle and sheep with particular attention in rumination time and rumen parameters. In conclusion, rumen mechanical stimulator is attributable to minimize metabolic problem associated with high concentrate feeding by providing mechanical stimulation on the rumen wall.
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Muramatsu, Tatsuo, Hidenori Kodama, Tohru Morishita, Mitsuhiro Furuse, and Jun-ichi Okumura. "Effect of intestinal microflora on digestible energy and fiber digestion in chickens fed a high-fiber diet." American Journal of Veterinary Research 52, no. 7 (July 1, 1991): 1178–81. http://dx.doi.org/10.2460/ajvr.1991.52.07.1178.

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Summary The effect of intestinal microflora on digestible energy (de) value and fiber digestion was studied in single-comb White Leghorn chickens fed a low-fiber diet (experiment 1) or a high-fiber diet with low or adequate metabolizable energy (me) value (experiment 2). Fecal energy excretion was calculated from the difference between total energy excretion in urinary and fecal droppings and urinary energy excretion, which was estimated from the energy values for individual urinary nitrogenous compounds extracted with Li2CO3. When the birds were fed the low-fiber diet, no differences in growth, de, or me were observed between germ-free and conventional environments. Of birds fed the high-fiber diet, growth of those in the conventional environment was similar to that of the birds in the germ-free environment at the adequate me value, whereas birds in the conventional environment grew faster than the birds in the germ-free environment at the low me value. Changes in observed dietary me values of the high-fiber diets, being higher in birds in the conventional environment than in birds in the germ-free environment (experiment 2), were almost entirely accounted for by those in dietary de values, most of which was contributed by crude fiber digestion. It was concluded, therefore, that by means of fiber digestion, the intestinal microflora may benefit the host bird by supplying extra energy, which would result in growth promotion, particularly when the bird is deficient in energy.
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Kehoe, F. Patrick, C. Davison Ankney, and Ray T. Alisauskas. "Effects of dietary fiber and diet diversity on digestive organs of captive Mallards (Anas platyrhynchos)." Canadian Journal of Zoology 66, no. 7 (July 1, 1988): 1597–602. http://dx.doi.org/10.1139/z88-233.

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We studied the effects of dietary fiber, of plant versus animal diets, and of diet diversity on the digestive organ morphology of captive Mallards (Anas platyrhynchos). Four experimental diets were used: whole corn (low fiber, plant), trout chow (low fiber, primarily animal), rabbit chow (high fiber, plant), and a diverse diet consisting of each of the preceding diets fed daily in random order. Every 5 days for 25 days, we sampled birds from each diet group (N = 6–8) and weighed each bird and its abdominal fat, gizzard, ceca, small intestine, and liver, and then measured its ceca and small intestine length. Other than differences explained by their different body sizes, the sex of the birds had no effect on gut measurements. Changes in body weight and abdominal fat weight suggested that Mallards existed equally well on each of the four diets, presumably because changes in their digestive organs allowed them to have similar digestive efficiencies when eating different diets. Birds on the high fiber diet had the largest digestive organs, but birds on all diets showed changes in digestive organs. The diverse diet produced effects on digestive organ morphology similar to those of the two low-fibre diets. Except for a larger gizzard for macerating corn in birds on that diet, there was no difference in the digestive organs between birds eating animal foods and those eating low fiber plant foods. The maximum weight of gizzard, intestine, and ceca of birds on the high fiber diet was reached in 10 days. However, ceca and intestine lengths of these birds were still increasing after 25 days. This observation suggests that birds can continue to respond to a change in diet after limits to the mass of their digestive organs have been reached.
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Migliori, Aubreyona, Robert Ward, Korry Hintze, and Kayden Stevenson. "Effect of Replacing Cellulose With Primarily Insoluble Fiber on the Microbiome and Short Chain Fatty Acids, and Fecal Calprotectin in Mice Fed a High Fat Diet." Current Developments in Nutrition 6, Supplement_1 (June 2022): 1021. http://dx.doi.org/10.1093/cdn/nzac069.026.

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Abstract Objectives Most semi-purified rodent diets contain only cellulose as the fiber source, and do not provide diverse fermentable substrates for the gut microbiota. The focus of this work was to determine how replacing cellulose with a mix of cereal fiber, pectin and beta-glucan affected the gut microbiota, short chain fatty acids, and fecal calprotectin in C57BL/6 mice. Methods Using a suggested, one day, adequate fiber human diet from the Institute of Medicine (IOM), the relative proportions of cellulose (57%), hemicellulose (20%), lignin (4%), pectin (15%) and beta-glucan (4%) were estimated using a food composition database. A combination of oat hull fiber, pectin and beta-glucan was added to a 45% kcal from fat rodent diet to provide these fiber sources at the typical US nutrient density (9g/1000 kcal), or at the IOM recommended level (14 g/1000 kcal). Mice were fed the experimental diets for 16 weeks. Cecal and fecal samples were collected at the end of the study and the microbiome was determined by 16S rRNA sequencing, short chain fatty acids by GC-FID, and fecal calprotectin by ELISA. Results There were no differences in weight gain, final weight, and lean mass, but for mice fed the low fiber diet there was a trend for lower % fat mass (p = 0.08). There were no differences in either alpha or beta diversity in the cecal or fecal microbiome samples. According to the Linear discriminant analysis Effect Size (LEfSe), at the genus level, the DIO diet was characterized by Lactococcus, the high fiber diet by Allobaculum, and the low fiber diet by Enterococcus. There were no significant differences in cecal SCFAs, but there was a trend for mice fed the high fiber diet to have more acetate (p = 0.053) and less isobutyrate (p = 0.06) and isovalerate (p = 0.07). There were no differences in empty cecum weight nor colon length. However, mice fed the low fiber diet had significantly more fecal calprotectin than mice fed the DIO or high fiber diets (p < 0.01). Conclusions Adding a blend of purified fibers to the DIO diet resulted in few effects on the microbiome composition or metabolism. However, there was a trend for mice fed the higher fiber to have less body fat. In addition, increasing the fiber intake from typical US levels to those recommended by the IOM was associated with less gut inflammation, as measured by calprotectin. Funding Sources Funded by the National Institute of Food and Agriculture.
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Offringa, Lisa C., Jennifer C. Hartle, Joseph Rigdon, and Christopher D. Gardner. "Changes in Quantity and Sources of Dietary Fiber from Adopting Healthy Low-Fat vs. Healthy Low-Carb Weight Loss Diets: Secondary Analysis of DIETFITS Weight Loss Diet Study." Nutrients 13, no. 10 (October 16, 2021): 3625. http://dx.doi.org/10.3390/nu13103625.

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The daily intake of dietary fiber is well below the recommended levels in the US. The effect of adopting a low-fat vs. a low-carbohydrate weight loss diet on fiber intake is of interest but not well-documented, especially when both approaches promote high-quality food choices. The objective of this paper is to compare the quantity and sources of dietary fiber between a healthy low-fat (HLF) vs. healthy low-carbohydrate (HLC) diet group when consumed over 12 months in a weight loss diet study. In this secondary analysis of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) study, the amount and sources of dietary fiber were examined in generally healthy adults, 18–50 years of age, Body Mass Index (BMI) 28–40 kg/m2, randomized to HLF or HLC for 12 months, who had available 24-h recalls at 0 (n = 609), 3 (n = 549), 6 (n = 491), and 12 (n = 449) months. The dietary intake was estimated by the Nutrition Data System for Research (NDS-R). The sources of fiber were determined for the major food groups. Significantly more total dietary fiber was consumed by HLF at every post-randomization time point, and, at 12 m, was 23.04 ± 9.43 g vs. 18.61 ± 8.12 g for HLF vs. HLC, respectively, p < 0.0001. In both diet groups at 12 months, the highest amount of dietary fiber came from non-starchy vegetables (4.13 ± 3.05 g and 5.13 ± 3.59 g). The other primary sources of fiber at 12 months for the HLF group were from whole grains (3.90 ± 3.13 g) and fruits (3.40 ± 2.87 g), and, for the HLC group, were from plant protein and fat sources, such as nuts and seeds, their butters, and avocados (2.64 ± 2.64 g). In the DIETFITS study, the difference in the total fiber intake for the HLF vs. HLC groups was more modest than expected. The HLC group consumed reasonably high amounts of fiber from high-protein and high fat plant-based sources.
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Arts, Cor JM, Carin ARL Govers, Henk van den Berg, and Jos HH Thijssen. "Effects of wheat bran and energy restriction on onset of puberty, cell proliferation and development of mammary tissue in female rats." Acta Endocrinologica 126, no. 5 (May 1992): 451–59. http://dx.doi.org/10.1530/acta.0.1260451.

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Delayed onset of puberty and mammary development is assumed to reduce the risk of mammary cancer. An animal experiment was performed to investigate the influence of dietary fiber, which is known to affect hormonal balance, on these characteristics. Forty-five immature female rats were randomized into three groups, which were fed ad libitum a low-fiber diet ( <0.5% dietary fiber based on white wheat flour), a high-fiber diet (9.2% dietary fiber based on wheat bran), or an energy-restricted low-fiber diet providing 90% of the energy of the ad libitum low-fiber diet. Energy intake in the second and third groups was similar. Wheat bran slightly delayed onset of puberty, whereas restricted energy intake delayed onset of puberty by about six days. At 48–58 days of age, 14 rats of the low-fiber group, 10 of the high-fiber group and 7 of the restricted group were in cycle. Development of mammary tissue was rudimentary in rats of the energy-restricted low-fiber group, stronger in the high-fiber group and strongest in the ad libitum low-fiber group. Cell proliferation in mammary tissue was similar for both groups fed ad libitum, but significantly lower in the restricted group. Peroxidase activity, a biomarker for estrogenicity, was lower in the high-fiber group than in the two low-fiber groups. It is concluded that wheat bran and, even more effectively, an imposed restricted energy intake delays onset of puberty and mammary development. This shortens the time for mammary cells to be initiated to tumor cells and hence reduces the risk of mammary cancer development. It seems that wheat bran acts via a reduced energy intake. However, that wheat bran plays a role in the delay of mammary development due to a reduced exposure to estrogen cannot be excluded.
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Jin, Shunshun, Charith U. B. Wijerathne, Kathy K. W. Au-Yeung, Huaigang Lei, Chengbo Yang, and Karmin O. "PSX-A-5 Effects of High- and low-Fiber Diets on Growth Performance and Intestinal Oxidative Stress in Growing-Finishing Pigs." Journal of Animal Science 100, Supplement_3 (September 21, 2022): 280–81. http://dx.doi.org/10.1093/jas/skac247.510.

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Abstract Feed is the most expensive input in commercial pork production. In order to reduce feed costs, using high-fiber ingredients has become a common practice. Moderate levels of fiber can maintain intestinal physiological function and promote intestinal health. Oxidative stress is linked to impaired nutrient absorption and growth performance. This study investigated the effects of high-fiber (HF, 6% crude fiber) and low-fiber (LF, 3% crude fiber) diets on growth performance and intestinal oxidative stress parameters in growing-finishing pigs. Forty growing pigs (27.07 ± 1.26 kg BW) were randomly assigned to 2 treatments with 10 replicates of 2 pigs per pen. Pigs were weighed on days 35, 42 and 70. The feed intake was recorded daily to calculate growth performance parameters. On day 70, eight pigs in each treatment group were randomly selected and euthanized to obtain jejunum to measure oxidative stress status. Pigs fed an HF diet were heavier than those fed an LF diet on days 35, 42 and 70 (P &lt; 0.05). During the whole feeding period, pigs fed an HF diet had higher average daily gain than those fed an LF diet (P &lt; 0.05). The LF diet resulted in increased levels of malondialdehyde (P &lt; 0.05) in the jejunum, suggesting that the LF diet contributed to oxidative stress in the jejunum. The LF diet also led to a significant increase in glutathione and oxidized glutathione levels (P &lt; 0.05) in the jejunum, indicating that pigs fed an LF diet needed to produce more antioxidant substances to cope with oxidative stress in the intestine. This was accompanied by a significant increase in glutamate-cysteine ligase in the jejunum of the LF group (P &lt; 0.05). These results suggest that the HF diet can improve growth performance and maintain intestinal health in growing-finishing pigs by reducing intestinal oxidative stress.
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Arts, Cor JM, and Jos HH Thijssen. "Effects of wheat bran on blood and tissue hormone levels in adult female rats." Acta Endocrinologica 127, no. 3 (September 1992): 271–78. http://dx.doi.org/10.1530/acta.0.1270271.

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The protective effect of dietary fiber on breast cancer development might be explained by the interaction between dietary fiber and hormonal processes. We studied the effects of dietary fiber and the effects of a reduced energy intake on the exposure of mammary tissue to both estrogens and progesterone, as well as the blood plasma levels of these steroids and of LH and FSH. Adult female Fisher rats were fed ad libitum either a low-fiber diet (0.5% dietary fiber based on wheat flour) or a high-fiber diet (9.2% dietary fiber based on wheat bran). A third group was used to control for the reduced energy intake of the high-fiber group and was fed the low-fiber diet restricted. Energy intake was similar for the second and third groups. Four out of 14 rats of the high-fiber group and 4 out of 15 rats of the restricted low-fiber groups were not in cycle after seven weeks on the experimental diets, indicating that the estrous cycle was significantly affected by a reduced energy intake. Exposure of mammary tissue to estrogens did not differ among the groups, as measured by estrone, estradiol-17β, estriol and peroxidase activity. During the peak period, plasma LH levels were significantly higher in the high-fiber group than in the two low-fiber groups. FSH and progesterone plasma levels were unaffected by the experimental diets. It is concluded that dietary fiber affects the hormonal processes involved in breast cancer development. The increased LH levels indicate an increased estrogen production in the ad libitum high-fiber group.
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36

Wei, Wei, Wei Sun, Shanshan Yu, Yu Yang, and Limei Ai. "Butyrate production from high-fiber diet protects against lymphoma tumor." Leukemia & Lymphoma 57, no. 10 (February 17, 2016): 2401–8. http://dx.doi.org/10.3109/10428194.2016.1144879.

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37

Rose, D. P., M. Goldman, J. M. Connolly, and L. E. Strong. "High-fiber diet reduces serum estrogen concentrations in premenopausal women." American Journal of Clinical Nutrition 54, no. 3 (September 1, 1991): 520–25. http://dx.doi.org/10.1093/ajcn/54.3.520.

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38

Peery, Anne F., Patrick R. Barrett, Doyun Park, Albert J. Rogers, Joseph A. Galanko, Christopher F. Martin, and Robert S. Sandler. "A High-Fiber Diet Does Not Protect Against Asymptomatic Diverticulosis." Gastroenterology 142, no. 2 (February 2012): 266–72. http://dx.doi.org/10.1053/j.gastro.2011.10.035.

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39

Ullrich, I. H. "Evaluation of a high-fiber diet in hyperlipidemia: a review." Journal of the American College of Nutrition 6, no. 1 (February 1987): 19–25. http://dx.doi.org/10.1080/07315724.1987.10720161.

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40

Snapp, Carol A. "HIGH-FIBER, LOW-FAT DIET HAS LITTLE EFFECT ON WEIGHT." Journal of Midwifery & Women's Health 51, no. 3 (May 6, 2006): 229–30. http://dx.doi.org/10.1016/j.jmwh.2006.01.010.

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41

Schmidt-Wittig, U., M. L. Enss, M. Coenen, K. Gärtner, and H. J. Hedrich. "Response of Rat Colonic Mucosa to a High Fiber Diet." Annals of Nutrition and Metabolism 40, no. 6 (1996): 343–50. http://dx.doi.org/10.1159/000177936.

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TRIFFONI-MELO, Andresa de Toledo, Margaret de CASTRO, Alceu Afonso JORDÃO, Vânia Aparecida LEANDRO-MERHI, Ingrid DICK-DE-PAULA, and Rosa Wanda DIEZ-GARCIA. "HIGH-FIBER DIET PROMOTES METABOLIC, HORMONAL, AND SATIETY EFFECTS IN OBESE WOMEN ON A SHORT-TERM CALORIC RESTRICTION." Arquivos de Gastroenterologia 60, no. 2 (June 2023): 163–71. http://dx.doi.org/10.1590/s0004-2803.202302022-96.

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ABSTRACT Background: Several mechanisms, including excessive hunger, account for patients’ difficulties in maintaining weight loss and dietary changes after caloric restriction. Objective: To evaluate the effect of short-term high-fiber calorie-restricted diet in appetite-regulating hormones, and hunger and satiety sensations in women with obesity. Methds: In a randomized controlled trial study, thirty women with body mass index (BMI) higher than 30 kg/m2, and aged from 20 to 50 years were hospitalized following a calorie-restricted diet (1000 kcal/day) for three days. The experimental group (n=15) received high-fiber diet and the control group (n=15), conventional diet. Body weight, BMI, resting energy expenditure (REE), acylated and total ghrelin, leptin, insulin and glucose, and hunger and satiety sensations were evaluated. Linear regression models with mixed effects (fixed and random effects) helped to assess the variables between the two groups and within the groups. Results: Body weight and BMI decreased in both the experimental and control groups (P<0.001). After the high-fiber diet, postprandial acylated ghrelin (P=0.04), glucose (P<0.001), insulin (P=0.04), and leptin (P=0.03) levels as well as the HOMA-IR index (P=0.01) decreased, whereas satiety improved (P=0.02). Obese women that followed the conventional diet had increased body fat percentage (P=0.04) and lower REE (P=0.02). The two diets did not differ in terms of hunger sensation. Conclusion: A short-term high-fiber diet improves satiety sensations and metabolic parameters while suppressing postprandial acylated ghrelin (60 minutes) and maintaining the resting energy expenditure.
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Sarathi, Vijaya, Anish Kolly, Hulivana Boranna Chaithanya, and Chinthamani Suryanarayana Dwarakanath. "Effect of Soya based Protein Rich Diet on Glycaemic Parameters and Thyroid Function Tests in Women with Gestational Diabetes Mellitus." Romanian Journal of Diabetes Nutrition and Metabolic Diseases 23, no. 2 (June 1, 2016): 201–8. http://dx.doi.org/10.1515/rjdnmd-2016-0024.

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AbstractBackground and Aims: Medical nutrition therapy plays a major role in the management of gestational diabetes mellitus (GDM). However, control of postprandial blood glucose values is often a challenge in Asian Indian GDM women due to high carbohydrate content in Indian diet.Materials and Methods: Women presenting with GDM diagnosis were randomised to high fiber complex carbohydrate diet and soya based protein rich diet (25% of cereal part in the high fiber, complex carbohydrate diet replaced by soya food) groups.Results: At the end of one week after initiation of dietary intervention, patients who received high fiber complex carbohydrate diet (n=30) had significantly higher postprandial blood glucose levels than those who received soya based protein rich diet (n=32). The need for insulin therapy at the end of one week after initiation of dietary intervention (15.62% vs. 40.0%) and at delivery (18.75% vs. 50%) were significantly lower in soya based protein rich diet group. Maternal thyroid function at diagnosis of GDM and delivery and neonatal TSH were not significantly different between the groups.Conclusion: Consumption of soya based protein rich diet reduced the need for insulin therapy in subjects with GDM. Short term consumption of soya food did not alter maternal and neonatal thyroid functions.
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Erceg, J. A., J. G. Wiegert, R. Becerra, M. T. Knauer, and E. van Heugten. "269 Growth performance and carcass traits of low- and high-fiber diet selection lines of pigs fed either low- or high-fiber diets." Journal of Animal Science 95, suppl_2 (March 1, 2017): 129–30. http://dx.doi.org/10.2527/asasmw.2017.269.

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Sunarti, Sunarti, Umar Santoso, Abrory Agus Cahya Pramana, Emy Huriyati, and Dianandha Septiana Rubi. "High Fiber and Beta Carotene from Sweet Potatoes and Pumpkin Improve Insulin Resistance by Inhibition of Sterol Regulatory Binding Protein 1c in Liver of Hypertriglyceridemic Rats." Open Access Macedonian Journal of Medical Sciences 8, A (November 12, 2020): 898–903. http://dx.doi.org/10.3889/oamjms.2020.5354.

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BACKGROUND: High sterol regulatory binding protein 1c (SREBP-1c) gene expression increases triglyceride synthesis, which induces insulin resistance. Short-chain fatty acids (SCFAs) from fiber fermentation and beta carotene may inhibit SREBP-1c gene expression. AIM: The aim of this study was to evaluate the high fiber and beta carotene diet on improving insulin resistance in hypertriglyceridemia rats. METHODS: A total of 25 Wistar male rats were divided into five groups: (1) Normal control (NC); (2) hypertriglyceridemia control (HC); (3) hypertriglyceridemia rats with treatment 1 (HT1); (4) hypertriglyceridemia rats with treatment 2 (HT2); and (5) hypertriglyceridemia rats with treatment 1 (HT3). The HT1, HT2, and HT3 received fiber 1.0 g; 2.0 g; and 3.1 g and beta carotene 725.7 μg; 1451.5 μg; and 2177.2 μg per day, respectively, for 6 weeks. The HC received high fat and fructose diet and the NC received a standard diet. The levels of triglyceride were analyzed using the colorimetric method before and after treatment. At the end of the study, the expression of SREBP-1c was identified by a quantitative polymerase chain reaction. RESULTS: High fat and fructose diet increased the levels of triglyceride (36.53 ± 1.27 vs. 119.79 ± 7.73), but high fiber and beta carotene diet can reduce triglyceride levels in HT1 (94.58 ± 4.53 vs. 77.70 ± 7.97); HT2 (115.58 ± 4.76 vs. 66.90 ± 3.11); and HT3 (103.87 ± 7.47 vs. 62.06 ± 4.45). The decreased triglyceride levels were related to low SREBP-1c gene expression, especially in the liver. Low SREBP-1c gene expression was correlated with homeostatic model assessment of insulin resistance index with r = 0.414; p < 0.05 in the liver and r = 0.158; p > 0.05 in white adipose tissues. CONCLUSION: High fiber and beta carotene diet can improve insulin resistance through inhibition of SREBP-1c gene expression.
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Hjorth, Mads, George Bray, Yishai Zohar, Lorien Urban, Derek Miketinas, Donald Williamson, Donna Ryan, et al. "Pretreatment Fasting Glucose and Insulin as Determinants of Weight Loss on Diets Varying in Macronutrients and Dietary Fibers—The POUNDS LOST Study." Nutrients 11, no. 3 (March 11, 2019): 586. http://dx.doi.org/10.3390/nu11030586.

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Efforts to identify a preferable diet for weight management based on macronutrient composition have largely failed, but recent evidence suggests that satiety effects of carbohydrates may depend on the individual’s insulin-mediated cellular glucose uptake. Therefore, using data from the POUNDS LOST trial, pre-treatment fasting plasma glucose (FPG), fasting insulin (FI), and homeostatic model assessment of insulin resistance (HOMA-IR) were studied as prognostic markers of long-term weight loss in four diets differing in carbohydrate, fat, and protein content, while assessing the role of dietary fiber intake. Subjects with FPG <100 mg/dL lost 2.6 (95% CI 0.9;4.4, p = 0.003) kg more on the low-fat/high-protein (n = 132) compared to the low-fat/average-protein diet (n = 136). Subjects with HOMA-IR ≥4 lost 3.6 (95% CI 0.2;7.1, p = 0.038) kg more body weight on the high-fat/high-protein (n = 35) compared to high-fat/average-protein diet (n = 33). Regardless of the randomized diet, subjects with prediabetes and FI below the median lost 5.6 kg (95% CI 0.6;10.6, p = 0.030) more when consuming ≥35 g (n = 15) compared to <35 g dietary fiber/10 MJ (n = 16). Overall, subjects with normal glycemia lost most on the low-fat/high-protein diet, subjects with high HOMA-IR lost most on the high-fat/high protein diet, and subjects with prediabetes and low FI had particular benefit from dietary fiber in the diet.
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Wen, Song, Guifang Yuan, Cunya Li, Yang Xiong, Xuemei Zhong, and Xiaoyu Li. "High cellulose dietary intake relieves asthma inflammation through the intestinal microbiome in a mouse model." PLOS ONE 17, no. 3 (March 10, 2022): e0263762. http://dx.doi.org/10.1371/journal.pone.0263762.

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Numerous epidemiological studies have shown that a high dietary fiber intake is associated inversely with the incidence of asthma in the population. There have been many studies on the role of soluble dietary fiber, but the mechanism of action for insoluble dietary fiber, such as cellulose-the most widely existing dietary fiber, in asthma is still unclear. The current study investigated the outcomes of a high-cellulose diet in a mouse model of asthma and detected pathological manifestations within the lungs, changes in the intestinal microbiome, and changes in intestinal short-chain fatty acids (SCFAs) in mice. A high-cellulose diet can reduce lung inflammation and asthma symptoms in asthmatic mice. Furthermore, it dramatically changes the composition of the intestinal microbiome. At the family level, a new dominant fungus family Peptostreptococcaceae is produced, and at the genus level, the unique genus Romboutsla, [Ruminococcus]_torques_group was generated. These genera and families of bacteria are closely correlated with lipid metabolism in vivo. Many studies have proposed that the mechanism of dietary fiber regulating asthma may involve the intestinal microbiome producing SCFAs, but the current research shows that a high-cellulose diet cannot increase the content of SCFAs in the intestine. These data suggest that a high-cellulose diet decreases asthma symptoms by altering the composition of the intestinal microbiome, however, this mechanism is thought to be independent of SCFAs and may involve the regulation of lipid metabolism.
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Metz, Mickie, Dave Chamberlin, Janet C. Remus, Garrett Rozeboom, Jaron Lewton, Leah M. Kellesvig, Veronica I. Polniak, and Dale W. Rozeboom. "274 Xylanase Significantly Improves Feed Efficiency in High Fiber Diets." Journal of Animal Science 101, Supplement_3 (November 6, 2023): 191–92. http://dx.doi.org/10.1093/jas/skad281.232.

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Abstract Feed is the greatest expense in pig production and improving efficiency while utilizing lower priced ingredients can help ameliorate this cost. The objective of this experiment was to determine the impact of utilizing a xylanase enzyme (Danisco Xylanase, IFF) on growth performance of pigs fed high fiber diets. We hypothesized that feeding xylanase would improve G:F and ADG when added to a greater fiber diet. To test this hypothesis, 672 PIC 359 x Yorkshire pigs were randomly allotted to pens based on body weight at an average age of 20.8 ± 1.0 d. Pens were randomly assigned to one of the following treatments: Control corn/soy diet (CON), Greater fiber diet (up to 40% dried distillers grains and 10% wheat middlings FIB), and Greater fiber diet plus xylanase (XYL). The CON and the FIB diets were formulated to contain the same net energy. In the XYL treatment, xylanase was added on top of the GF diet with no reformulation or energy release assigned to the xylanase. All pigs were weighed and feed disappearance was measured weekly to calculate ADG, ADFI, and G:F. Growth performance data were analyzed using the PROC MIXED procedure in SAS with pen as the experimental unit. There were 17 pens per treatment for CON and FIB and 16 pens per treatment for the XYL treatment. To increase the number of replicates, the trial was conducted over 3 consecutive turns of pigs. Dietary treatment, repetition, week, and two-way interactions were fixed effects. Results were considered significantly different at P ≤ 0.05. In the 7-week nursery period, the pigs fed CON had increased ADG (CON: 0.52 kg/d, FIB: 0.48 kg/d, XYL: 0.48 kg/d) and ADFI (CON: 0.85 kg/d, 0.81 kg/d, 0.80 kg/d) when compared with FIB and XYL treatments (P ≤ 0.05). There were no differences in growth performance between the pigs fed FIB and the pigs fed XYL in the nursery phase. At the end of the nursery phase, pigs were randomly allotted within treatment to different cohorts in the growing finishing period. In the 12-wk growing finishing period, pigs fed FIB and XYL had decreased ADG compared with pigs fed Control diets (CON: 1.05 kg/d, FIB: 0.97 kg/d, XYL: 0.96 kg/d; P ≤ 0.05). In addition, pigs fed XYL diets had improved G:F when compared with both FIB and CON (CON: 0.402, FIB: 0.400, XYL: 0.414; P ≤ 0.05). This improvement in feed efficiency in the XYL treatment seemed to be driven by a significant reduction in ADFI (P ≤ 0.05), which suggests, adding xylanase to a diet without accounting for energy release, reduces overall feed intake and growing more efficiently, as expected with more available energy.
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Kayode, Omowumi Titilola, Abolanle A. A. Kayode, and TENIOLA OYEBODE. "Chemometric analysis of ketogenic diet formulated from low-cost dietary fibers." Functional Foods in Health and Disease 12, no. 1 (January 31, 2022): 46. http://dx.doi.org/10.31989/ffhd.v12i1.857.

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Background: Ketogenic diet (KD) is a beneficial nutritional plan consisting of low carbohydrate, high fat, and moderate protein levels and aids in amelioration of some metabolic disorders. The objective of this study is to develop a ketogenic diet model using cheap and readily available fiber sources. METHODS: Cabbage head and coconut fruits were obtained and processed into fiber and ketogenic diet chow. They were further analyzed using standard methods for proximate, mineral, and heavy metals, phytochemicals, and DPPH radical scavenging assay.RESULTS: Carbohydrate content of the samples were (3.35, 4.00, 3.16 and 2.08%) for cabbage feed, coconut feed, coconut fiber, and cabbage fibers, respectively. This conforms to the maximal 4% carbohydrate required for ketogenic diet daily allowable limit. Other nutrients such as lipids and proteins were in high and moderate amounts respectively. Phytochemicals were also present in varied proportions in the samples. CONCLUSION: The developed cabbage and coconut fiber is an appropriate fiber source for ketogenic diet preparation. They are rich in nutrients based on their mineral content. They may be positioned as a nutraceutical for therapeutic and disease prevention action due to their inherent bioactive chemicals and radical scavenging activity. They may pose negligible toxicity risks as the few detected heavy metals are within permissible limits. KEYWORDS: Fibers, ketogenic diet, cabbage, coconut, chemical analysis, and antioxidant
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Stevenson, Kayden, and Robert Ward. "Effect of Optimizing Fiber Intake of Mice on Weight Gain, Fat Mass, Oral Glucose and Insulin Tolerance Tests in Mice Fed a High Fat Diet." Current Developments in Nutrition 6, Supplement_1 (June 2022): 536. http://dx.doi.org/10.1093/cdn/nzac077.039.

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Abstract Objectives In humans, fiber intakes close to recommended levels (14g/1000 kcal, Institute of Medicine (IOM)) are associated with less chronic disease. In most semi-purified rodent diets, the only fiber source is cellulose. The main objective of this work was to determine if substituting a complex fiber blend for cellulose would affect metabolism of mice fed a 45% kcal from fat diet. Methods To model a recommended human fiber profile for rodents, the relative proportions of cellulose, hemicellulose, lignin, pectin and beta-glucan were estimated from a one-day meal plan with the recommended fiber level using a food fiber composition database. Subsequently, a mix of oat hull fiber, pectin and beta-glucan was added to a high-fat rodent diet at the typical US intake or at the recommended level (8 g/1000kcal (low), 14 g/1000 kcal (high)). Three groups of C57Bl/6 mice (n = 12) were fed the experimental diets for 16 weeks. The third diet was also high fat but only contained cellulose. Body composition was measured by MRI at weeks 7 and 14. Oral glucose tolerance tests (OGTT) and insulin tolerance tests (ITT), were conducted at weeks 8 and 15 (OGTT) and week 16 (ITT). Results There were no differences in final weight or weight gain in mice between the groups. There was a trend for mice fed the low complex fiber profile diet to have a higher body fat percentage than mice fed the other groups (p = 0.08). However, there were no differences in fasting glucose at week 8 or 15, and no significant differences in OGTT or ITT between the groups. Conclusions Rodent models are used extensively to investigate the role of nutrients in maintaining metabolic health and the prevention of chronic disease. These results indicate that exogenous fiber added to a high fat, semi-purified rodent diet does not improve body composition or glucose metabolism in mice. Funding Sources The National Institute of Food and Agriculture (NIFA).
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