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Dissertations / Theses on the topic 'High level resistance to glycopeptides'

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1

Borowczak, Mike. "Side channel attack resistance| Migrating towards high level methods." Thesis, University of Cincinnati, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3601397.

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<p> Our world is moving towards ubiquitous networked computing with unstoppable momentum. With technology available at our every finger tip, we expect to connect quickly, cheaply, and securely on the sleekest devices. While the past four decades of design automation research has focused on making integrated circuits smaller, cheaper and quicker the past decade has drawn more attention towards security. Though security within the scope of computing is a large domain, the focus of this work is on the elimination of computationally based power byproducts from high-level device models down to phys
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2

Panchal, Viralkumar. "The molecular basis of high-level methicillin resistance in Staphylococcus aureus." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/22036/.

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3

Martin, Deborah J. H. Martin. "Understanding microbial survival in, and the development of resistance to, high-level disinfection." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/55865/.

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High-level disinfection is employed throughout the health services in the disinfection of medical equipment, such as endoscopes, to prevent patient-to-patient infections. The likelihood of an endoscope transmitted infection occurring is rare, providing strict guidelines are followed for effective decontamination between procedures. Endoscopes are subjected to rigorous cleaning and high-level disinfection within washer-disinfectors. However, poor decontamination protocols and inappropriate use of disinfectants can lead to can lead to incomplete disinfection and resistance. A number of bacterial
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4

Barnard, Danielle. "Conjugative Transfer Pathways of High-Level Mupirocin Resistance and Conjugative Transfer Genes in Staphylococcus." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etd/2188.

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To combat widespread infections caused by Staphylococcus aureus, mupirocin was introduced at the Veterans Affairs Medical Center, Mountain Home, Tennessee. Soon after introduction, high-level mupirocin-resistance emerged. The rapid emergence was hypothesized to be due to conjugative transfer of the mupA resistance gene from S. epidermidis to S. aureus. Results have shown that transfer of high-level mupirocin-resistance from S. aureus donors commonly occurs. However, transfer from naturally-occurring S. epidermidis donors was not attainable. Staphylococcus epidermidis transconjugants, how
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5

Breece, Robert M. "Spectroscopic Characterization of Co(II)-Substituted VanX, a Zn(II)-Dependent Dipeptidase Required for High-Level Vancomycin Resistance." Miami University / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=miami1077576564.

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6

Saeedi, Baharak. "Characterization of clinical enterococcal isolates in Swedish hospitals : studies on genetic relatedness and high-level gentamicin resistance /." Linköping : Dept. of Molecular and Clinical Medicine, Univ, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/med899s.pdf.

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7

Pirapatrungsuriya, Komson. "Fluoroquinolone action and resistance : action of ciprofloxacin in a standard Escherichia coli and the roles of GyrA and ParC mutations in high-level resistance." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/22559.

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Bacterial isolates from Malaysia and Thailand were obtained, characterised and tested for their MIC of ciprofloxacin (Cip). Some were found to be extremely resistant including three <I>Acinetobacter baumannii</I> (MIC of 128 mg/L). <I>GyrA </I>and <I>parC</I> are homologous genes and are subunits of enzyme DNA gyrase and topoisomerase IV, respectively. Three <I>E. coli</I> (MIC of 128 mg/L) had two mutations in <I>GyrA</I> (Ser-83 to Leu and Asp-87 to Tyr) and one mutation in <I>parC</I> (Ser-83 to lle). Another <I>E. coli</I> (MIC of 32 mg/L) had the same three mutations except at <I>gyrA</I>
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8

Dhakal, Shankar. "Circuit Level Reliability Considerations in Wide Bandgap Semiconductor Devices." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1532703747534188.

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9

Delgado, Marlene Patrícia Pereira Ferreira. "Detecção de alto nível de resistência a aminoglicosídeos em estirpes clínicas de enterococci." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2015. http://hdl.handle.net/10400.5/9144.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Os Enterococcus emergiram como agentes patogénicos nosocomiais importantes, com o aparecimento cada vez mais frequente de estirpes multi-resistentes. São intrinsecamente resistentes a várias classes de antibióticos, por exemplo as cefalosporinas, baixas concentrações de aminoglicosídeos, lincosamidas e estreptograminas (Enterococcus faecalis). Adicionalmente, apresentam capacidade de adquirir resistência a outros antibióticos, sendo cada vez mais frequente a ocorrência de resistência à penicilina, cloranfenicol, macrólidos, tetracicl
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10

Sasikumar, Anup. "Quantitative spectroscopy of reliability limiting traps in operational gallium nitride based transistors using thermal and optical methods." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1415298691.

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11

Dufour, Robin. "Différentes approches de l'optimisation du traitement du cancer du sein de phénotype "basal like" triple négatif par un anti-PARP : contournement des protéines "Multidrug Resistance" et traitement combiné radiothérapie / chimiothérapie. Spécialité." Thesis, Clermont-Ferrand 1, 2016. http://www.theses.fr/2016CLF1MM05/document.

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Le cancer du sein de phénotype « Basal-like » triple négatif (BLTN) est particulièrement agressif et de mauvais pronostic. Il est insensible aux traitements hormonaux laissant pour seule stratégie de traitement la chimiothérapie conventionnelle. De ce fait, de nouvelles thérapeutiques ciblées sont en développement, tels que les inhibiteurs de la Poly-ADP-Ribose-Polymerase (PARP). Dans ce contexte, nos travaux de recherche ont été orientés sur l’optimisation du traitement des cancers du sein BLTN en modélisant l’action d’un anti-PARP modèle, l’Olaparib sur la lignée SUM1315 de phénotype BLTN. D
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12

"Conjugative Transfer Pathways of High-Level Mupirocin Resistance and Conjugative Transfer Genes in Staphylococcus." East Tennessee State University, 2006. http://etd-submit.etsu.edu/etd/theses/available/etd-0330106-102200/.

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13

Wylie, Barbara A. "Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa." Thesis, 1991. https://hdl.handle.net/10539/25842.

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A thesis submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements of Doctor of Philosophy. Johannesburg 1991<br>Trimethoprim is a broad-spectrum antimicrobial agent frequently used either in combination with sulphamethoxazole (cotrimoxazole) or alone in the treatment of urinary and respiratory tract infections. Since the introduction of this drug in 1969 resistance to it has been monitored in several centres in Europe continuously but only intermittently in the United States of America and developing countries in Africa, Asia, Cent
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14

Singh, Cathleen. "Phenotypic and genotypic characterization of high-level macrolide and lincosamide resistance in Corynebacterium species in Canada and the distribution of the ermX resistance determinant among Corynebacterium species." 2010. http://hdl.handle.net/1993/3974.

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Specific bacterial commensals demonstrating multidrug resistance (MDR) are opportunistic pathogens for immunocompromised patients, including Corynebacterium species (spp.). Severe infections due to MDR corynebacteria are being increasingly reported where several MDR phenotypes have been described. One such phenotype, the macrolide-lincosamide-streptogramin B phenotype (MLSB), is characterized by high-level resistance to macrolides, lincosamides, and streptogramin B. Resistance is thought to be attributable to acquisition of the ermX gene, a methyltransferase that alters the ribosomal macrolide
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15

Carrara, Elena. "SAVE ‘Stewardship Antibiotica Verona’: a quality improvement project to reduce in-hospital antibiotic consumption in a setting with a high level of antimicrobial resistance." Doctoral thesis, 2021. http://hdl.handle.net/11562/1046021.

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Background: According to recent estimates from the European Centre for Disease Prevention and Control, Italy is the European country with the highest disease burden due to antimicrobial resistance (AMR). In line with the recommendations from the National Plan for Combating Antibiotic Resistance in Italy, in June 2018, the Verona University hospital started a quality improvement Antibiotic Stewardship (AS) intervention aimed at reducing antibiotic consumption and infections sustained by targeted AMR pathogens. Methods: The core elements of the SAVE (Stewardship Antibiotica VErona) intervention
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16

Tshubwana, T. S. "The role of the principal in managing change at secondary school level in the Limpopo Province." Diss., 2007. http://hdl.handle.net/10500/2148.

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The study was conducted in the secondary schools of Vhembe district. Five secondary schools were selected for study. Data were collected by interviews. Interview involved asking questions, listening and recording answers and then following up with additional relevant questions. The findings revealed that lack of training regarding change influences people to resist change. Therefore, before the initiation of any change, the Department of Education should train all stakeholders involved in the day-to-day implementation of change. This will minimize resistance during the implementation sta
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