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Dissertations / Theses on the topic 'High resolution melting analysis'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Dempsey, Nunez Laura. "Spectrum of mutations in MMAA identified by high resolution melting analysis." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110535.

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The gene product of MMAA is required for the intracellular metabolism of cobalamin (Cbl). Mutations in this gene lead to the cblA class of disorders, characterized by isolated methylmalonic aciduria. We have been concerned that somatic cell methods of diagnosis may miss patients with mild cellular phenotypes. A high resolution melting (HRM) analysis assay was developed to rapidly scan the coding exons and flanking intronic regions of the MMAA genes for variants. DNA from 96 unaffected reference individuals, 72 patients with complementation confirmed cblA, and 181 patients with elevated isolate

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2

Illson, Margaret. "Spectrum of mutations in MMAB identified by high resolution melting analysis." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110564.

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Pathogenic variants in the MMAB gene (OMIM 607958) are responsible for the cblB class of cobalamin-responsive methylmalonic aciduria (MMA) (OMIM 251110). MMAB encodes cobalamin adenosyltransferase, a mitochondrial enzyme responsible for the formation of adenosylcobalamin (AdoCbl). AdoCbl subsequently functions as a cofactor for methylmalonyl-CoA mutase (MCM) during the isomerization of L-methylmalonyl-CoA to succinyl-CoA. Somatic cells studies have been used to evaluate patient samples for cobalamin related disorders. Due to high basal levels of propionate incorporation, some patients wi

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3

Souza, Roberto Antonio de. "Genotipagem de linhagens de Yersinia spp. por high-resolution melting analysis." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-27062013-151724/.

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O gênero Yersinia pertence à família Enterobacteriaceae e compreende 17 espécies. Y. pestis, Y. pseudotuberculosis e Y. enterocolitica são reconhecidamente patógenos de humanos e animais. Y. pestis cause a peste. Y. pseudotuberculosis e Y. enterocolitica são agentes causadores, sobretudo, de gastroenterites transmitidas por água e alimentos. As demais 14 espécies são, usualmente, consideradas não-patogênicas, com exceção de Y. ruckeri sorogrupo O:1 que causa infecções em peixes. Nas últimas décadas, a tipagem molecular tornou-se uma importante ferramenta nos estudos filogenéticos de numerosos

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Darbandy, Ashna. "Optimization of High Resolution Melting Analysis for Detection of KRAS Gene Mutations." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-130751.

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<p><strong>Background: </strong>Mutations of the KRAS oncogene occur in a variety types of human tumors. By assessing the mutation status of KRAS, clinicians can predict patient response to anti-EGFR therapy such as cetuximab (Erbitux®) or panitumumab (Vectibix®) in patients with metastatic colorectal cancer. The aim of this study was to optimize a real-time PCR method followed by high resolution melting analysis (HRM) in a single step for detection of most common mutations within the KRAS gene. <strong>Methods:</strong> Seven DNA samples with predefined KRAS mutations and 19 tumor samples fro

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Burrows, Adria Michelle. "A comparative ancestry analysis of Y-chromosome DNA haplogroups using high resolution melting." University of the Western Cape, 2018. http://hdl.handle.net/11394/6536.

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>Magister Scientiae - MSc<br>The objective of this study is to deduce paternal ancestry using ancestry informative single nucleotide polymorphisms (SNPs) by means of High Resolution Melting (HRM). This was completed by producing a multiplex system that was designed in a hierarchical manner according to the YSNP tree. This project mainly focused on African ancestry and was used to infer paternal ancestral lineages on the Johannesburg Coloured population. South Africa has a diverse population that has ancestral history from across the globe. The South African Coloured population is the mo

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Michelle, Burrows Adria. "A comparative ancestry analysis of Y-chromosome DNA haplogroups using high resolution melting." University of the Western Cape, 2018. http://hdl.handle.net/11394/6489.

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Magister Scientiae - MSc (Biotechnology)<br>The objective of this study is to deduce paternal ancestry using ancestry informative single nucleotide polymorphisms (SNPs) by means of High Resolution Melting (HRM). This was completed by producing a multiplex system that was designed in a hierarchical manner according to the YSNP tree. This project mainly focused on African ancestry and was used to infer paternal ancestral lineages on the Johannesburg Coloured population. South Africa has a diverse population that has ancestral history from across the globe. The South African Coloured population i

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7

PIMENTEL, ROMERO CESAR HUGO. ""INNOVATIVE SIGNAL PROCESSING TECHNIQUES IN BIOENGINEERING: COMPRESSED SENSING AND HIGH RESOLUTION DNA MELTING ANALYSIS"." Doctoral thesis, Università degli studi di Ferrara, 2021. http://hdl.handle.net/11392/2487913.

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The first part starts with an introduction of the Compressed Sensing (CS) theory. After that, an overview of the state-of-the art of some CS adaptations by using additional priors in the different stages is presented in order to explain the new CS adaptation proposed in this work. Some of the CS adaptations reviewed are confronted using synthetic signals, synthetic electrocardiograph (ECG) signals and electroencephalographic (EEG) signals. The second part provides general concepts of biology and current developments in bioinformatics to read and and analyze the DNA. Questions like what a seque

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8

Tsang, Ho-yin, and 曾皓言. "Detection of clinically silent beta-globin gene mutations in Chinese using high resolution melting analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48334182.

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Mutations in the beta-globin (β-globin) gene cause beta-thalassaemia (β-thalassaemia).The screening strategy for β-thalassaemiais based on the value of mean corpuscular volume (MCV) from the complete blood count (CBC) data. Current laboratory practice considers blood samples with MCV higher than 80fL as normal. No further assessment will be done on these samples. However, there are clinically silent β-globin gene mutations with MCV higher than 80fL, for example, heterozygous haemoglobin E (HbE). The importance of finding out this kind of mutations is due to the serious outcome when they occur

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Ho, Sophia KW, and 何廣慧. "Detection of clinically silent alpha-globin gene mutations in Chinese using high resolution melting analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206558.

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α-thalassemia is an inherited globin gene disorder commonly found among the Chinese population. It is composed of both non-deletional and deletional α-globin gene mutations. Classical α-thalassemia presents with red cell microcytosis but silent cases with a normal mean corpuscular volume (MCV) are also seen. Routine laboratory testing methods for large-scale detection of silent α-thalassemia mutations are onerous and time-consuming. Furthermore, methods such as denaturing high performance liquid chromatography (HPLC) or denaturing gradient gel electrophoresis (DGGE) for scanning of point muta

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10

Ozbak, Hani. "The application of High Resolution Melting Analysis (HRMA) for rapid detection of bacteria responsible for bloodstream infections." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/the-application-of-high-resolution-melting-analysis-hrma-for-rapid-detection-of-bacteria-responsible-for-bloodstream-infections(b3d5c15b-9541-44c2-873c-f7a32fc60282).html.

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Background: The diagnosis of bloodstream infection is a significant challenge for healthcare providers and is often associated with severe illness (sepsis) and poor outcomes. Rapid detection and identification of pathogens followed by characterisation of antibiotic resistance could help direct early treatment and improve patient care. Standard blood culture methods, which usually take 2-5 days to complete, can confirm if there is a bacteraemia or not in suspected patients. However, molecular approaches have been developed and are being increasingly investigated to overcome disadvantages of cul

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Loiacono, M. "MOLECULAR CHARACTERIZATION BY RT-REAL TIME PCR AND HIGH RESOLUTION MELTING ANALYSIS FOR FOOD SAFETY AND VETERINARY DIAGNOSTICS." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/338720.

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This PhD thesis is the outcome of a range of activities and experimental results aimed to a better characterization of the risk that Escherichia coli and other microrganisms and parasites may pone to the health of animals and finally humans. One of the main activity of the present project was based on the test hypothesis that the virulence profile of E. coli strains toward bovine mammary gland can be modulated by the interaction with the host cells. These hypothesis were tested through a gene expression study of some virulence factors of six E. coli strains when co-cultured with a bovine mamma

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Brecht, Gadean. "Genetic analysis of mitochondrial DNA within Southern African populations." UWC, 2020. http://hdl.handle.net/11394/7365.

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>Magister Scientiae - MSc<br>As human beings we are curious about our origin and ancestry. A curiosity has led to an investigation of human evolution and expansion across the world by means of population genetics and phylo-genetics by evaluating a region in Southern Africa that is largely unknown. The objective of this study was to develop a quick, inexpensive and accurate hierarchical diagnostic screening system of the MtDNA phylogenetic tree, AI-SNPs in the mtDNA genome by using High Resolution Melting analysis to evaluate the population composition and ancestral haplogroups of Southern Af

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13

Raphela, Mashikoane Pinky Jane. "Molecular characterization of Mycoplasma synoviae in chickens in South Africa using single-stranded conformation polymorphism and high-resolution melting curve analysis of the vlhA gene." Diss., University of Pretoria, 2012. http://hdl.handle.net/2263/26196.

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Mycoplasma synoviae (Ms) causes respiratory infection and synovitis in chickens and turkeys and is an economically important pathogen of poultry worldwide. It is critically important to characterize Ms strains, especially in countries in which poultry flocks are vaccinated with the live attenuated Ms strain MS-H. Vaccination with this vaccine may cause sero-conversion and persistence of the vaccine strain in the respiratory tract and will frequently result in positive Ms cultures and PCR results. Vaccination of flocks therefore complicates the diagnosis of Ms by the presence of detectable anti

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Al_griw, Huda Hm. "Molecular detection of bloodstream pathogens in critical illness." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/molecular-detection-of-bloodstream-pathogens-in-critical-illness(5f143a31-3694-454c-8940-5ae434f1eb31).html.

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Background: Critically ill patients are at particular risk of developing bloodstream infection. Such infections are associated with the development of sepsis, leading to a marked increase in mortality rate. Early detection of the causative organism and appropriate antibiotic treatment are therefore critical for optimum outcome of patients with nosocomial infection. Current infection diagnosis is based on standard blood culture techniques. However, microbiological culture has a number of limitations, not least that it takes several days to confirm infection and is therefore not useful in direct

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Sedláková, Lucie. "Analýza DNA izolované z různých typů probiotických výrobků s využitím PCR v reálném čase a HRM analýzy." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2016. http://www.nusl.cz/ntk/nusl-240562.

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The aim of this diploma thesis was to introduce real-time PCR with high-resolution melting analysis for Bifidobacterium species. Currently a small number of publication, dealing with identification of Bifidobacterium species using high-resolution melting analysis, is available. According to publications dealing with identification of lactic acid bacteria were selected primers P1V1 and P2V1, LAC1 and LAC2, LsppUPF and LsppUPR, V3F and V3R, V6F and V6R. Using this primers bacterial DNA was amplified by real-time PCR with high-resolution melting analysis. After evaluation of the measured results

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Pires, Elisabete Sofia Videira. "Real-Time PCR, High Resolution Melting - aplicações forenses." Master's thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/10747.

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Mestrado em Biologia Molecular e Celular<br>Apontada como a maior revolução científica na área forense desde a descoberta das impressões digitais, a identificação humana por meio da análise do DNA tornou-se uma poderosa ferramenta de investigação, auxiliando na elucidação de casos forenses, baseando-se cientificamente na existência de polimorfismos genéticos ao longo do genoma em indivíduos diferentes, que faz com que cada pessoa possua um código genético único. Com a introdução da real-time PCR nas investigações forenses, tornou-se possível uma análise sensível e específica de regiões

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Konečná, Jana. "PROBIOTICKÉ GENY POTRAVINÁŘSKY VÝZNAMNÝCH BAKTERIÍ MLÉČNÉHO KVAŠENÍ." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-402108.

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Isolation of deoxyribonucleic acid (DNA) is an important step in the molecular diagnostics of microorganisms. A high quality of isolated DNA is necessary for DNA amplification by the polymerase chain reaction (PCR). The conventional DNA isolation using phenol chloroform extraction and DNA precipitation in ethanol is time consuming and requires the use of toxic phenol. Magnetic separation techniques using magnetic solid particles are one of modern methods to speed up the nucleic acids isolation. The aim of this work was to use two different types of magnetic particles for solidphase DNA extra

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Konečná, Jana. "Využití molekulárně biologických technik pro identifikaci a analýzu probiotických bakterií." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-402114.

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Isolation of deoxyribonucleic acid (DNA) is an important step in the molecular diagnostics of microorganisms. A high quality of isolated DNA is necessary for DNA amplification by the polymerase chain reaction (PCR). The conventional DNA isolation using phenol-chloroform extraction and DNA precipitation in ethanol is time-consuming and requires the use of toxic phenol. Alternative method of DNA isolation is use of commercially available kits which, however, are expensive and their efficiency is low. Magnetic separation techniques using magnetic solid particles are one of modern methods to speed

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Knápková, Monika. "Použití vysokorozlišovací analýzy křivek tání ke studiu baktérií mléčného kvašení." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-401890.

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Currently, there is a growing interest in the use of probiotic products, and there are many of them in the market. With the growing interest, greater emphasis is placed on the identification of declared probiotic microorganisms. Precise identification of microbial composition is often a difficult task and it requires more advanced methods especially in the field of molecular diagnostics. The diploma thesis was focused on the verification of the presence od declared probiotic microorganisms in probiotic food supplements GS Laktobacily Forte 21, Biopron 9 Premium and Linex® Forte. DNA was isolat

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Hamano, Yuya. "Forensic age prediction by use of methylation-sensitive high resolution melting." Kyoto University, 2018. http://hdl.handle.net/2433/232076.

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Salgado, Isa Sofia Ribeiro. "Deteção de mutações nos genes JAK2 e MPL por high resolution melting." Master's thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/12628.

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Mestrado em Biologia Aplicada<br>As NMPs representam um grupo heterogéneo de doenças clonais caracterizadas pela expansão e produção excessiva de eritrócitos, granulócitos e/ou plaquetas sanguíneas na medula óssea. Em 2005, foi identificada a mutação V617F no gene JAK2 numa elevada frequência de doentes com NMP, em especial nos doentes com PV (65-97%), TE (23-57%) e MFP (35-57%). A deteção da mutação V617F no gene JAK2 e de outras mutações funcionalmente similares, isto é, mutações no exão 12 do gene JAK2 e no exão 10 do gene MPL, foram recentemente incluídas pela Organização Mundial de Saúde,

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ALMEIDA, F. A. N. "AUTÊNTICAÇÃO de Ginseng Brasileiro Utilizando a Técnica de High Resolution Melting (hrm)." Universidade Federal do Espírito Santo, 2018. http://repositorio.ufes.br/handle/10/7113.

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Made available in DSpace on 2018-08-01T21:35:03Z (GMT). No. of bitstreams: 1 tese_12002_Dissertação_Francine Alves Nogueira de Almeida.pdf: 2009835 bytes, checksum: d864a01c75bbc516074e2befb4c57c5c (MD5) Previous issue date: 2018-02-20<br>À medida que a indústria de plantas medicinais cresce, a autenticidade de seus produtos é uma questão de segurança do consumidor e não pode ser negligenciada. O Ginseng brasileiro, por exemplo, se refere a duas espécies distintas, Pfaffia glomerata e Hebanthe eriantha. Apesar da similaridade entre essas duas espécies, o que dificulta a identificação morfoló

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Marques, Jefferson Luiz Brum. "High-resolution electrocardiogram analysis." Thesis, University of Sheffield, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263558.

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Chan, Ming-yan, and 陳明恩. "Rapid diagnosis of isoniazid resistant mycobacterium tuberculosis by high resolution melting (HRM) assay." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48333402.

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Mycobacterium tuberculosis (MTB) is a major infective agent causing human tuberculosis (TB) in the worldwide. Although tuberculosis can be treated by a six-month course of antibiotics, the prevalence of extensively drug-resistance TB (XDR-TB) made the disease becomes a global health problem. In addition to the conventional MTB detection methods, molecular methods become significant in drug resistant MTB detection which can enhance effective drug treatment. In this study, 200 MTB respiratory specimens were collected from patients with suspected tuberculosis in Tuen Mun Hospital in Hong Kong.

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Cury, Nathália Moreno. "Investigação de Mutações no Gene BRCA1 em Famílias Brasileiras com Suspeita da Síndrome Hereditária do Câncer de Mama e/ou Ovário." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/17/17135/tde-14062012-134410/.

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Cerca de 10% dos casos de câncer de mama e/ou ovário são caracterizados como hereditários, onde a presença de mutações germinativas no gene de suscetibilidade BRCA1 aumenta o risco de desenvolver esses cânceres durante a vida da mulher. O BRCA1 é um gene supressor tumoral envolvido na resposta de danos ao DNA, controle do ciclo celular, na remodelação da cromatina, ubiquitinação e regulação da transcrição. O presente estudo tem como objetivo central caracterizar as mutações do gene BRCA1 associadas a Síndrome Hereditária do Câncer de Mama e/ou Ovário (HBOC) em pacientes atendidos no Serviço de

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Park, Dongwook 1959. "High-resolution laser radar performance analysis." Thesis, Massachusetts Institute of Technology, 1988. http://hdl.handle.net/1721.1/14712.

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Hytch, Martin J. "Quantitative high resolution electron microscopy." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317785.

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Sarlo, Rodrigo. "High-Resolution, High-Frequency Modal Analysis for Instrumented Buildings." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/84477.

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Civil infrastructure failure is hard to predict, both in terms of occurrence and impact. This is due to combination of many factors, including highly variable environmental and operational conditions, complex construction and materials, and the sheer size of these structures. Often, the mitigation strategy is visual inspection and regular maintenance, which can be time-consuming and may not address root causes of failure. One potential solution to anticipating infrastructure failure and mitigating its consequences is the use of distributed sensors to monitor the physical state of a structure,

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Goode, Ashley Harford. "High resolution ultrasonic imaging system." Thesis, University of Portsmouth, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329278.

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Cox, K. B. "High resolution analysis of dispersed seismic signals." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375223.

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Lepidis, Polichronis. "High resolution frequency analysis in scanning probe microscopy." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=96834674X.

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Mundt, Laura Elena [Verfasser], and Stefan [Akademischer Betreuer] Glunz. "High-resolution analysis of perovskite absorbers in photovoltaics." Freiburg : Universität, 2018. http://d-nb.info/1181689929/34.

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Nakajima, Kaoru. "MONOLAYER ANALYSIS USING HIGH-RESOLUTION RUTHERFORD BACKSCATTERING SPECTROSCOPY." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/85403.

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Kyoto University (京都大学)<br>0048<br>新制・論文博士<br>博士(工学)<br>乙第12399号<br>論工博第4030号<br>新制||工||1477(附属図書館)<br>27429<br>UT51-2009-M905<br>京都大学大学院工学研究科機械物理工学専攻<br>(主査)教授木村健二, 教授井手亜里, 教授河合潤<br>学位規則第4条第2項該当

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MASIELLO, IRENE. "High-resolution epigenetic analysis of the cell nucleus." Doctoral thesis, Università degli studi di Pavia, 2018. http://hdl.handle.net/11571/1214856.

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In the interphase nucleus, DNA is necessarily organized around the histone core and, then, in higher order structures. At the electron microscope, dispersed euchromatin fibers and dark heterochromatin regions can be distinguished. The latter is divided in constitutive heterochromatin, reasonably localized at the periphery nearby the nuclear envelope and far from the perichromatin region where transcription occurs, and facultative heterochromatin, containing the genes undergoing silencing and activation (regulated genes) on the surface facing the perichromatin region. Chromatin structure affect

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Gatcombe, Christopher Peter. "Computer modelling of high resolution ultrasonic transducers." Thesis, City University London, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236597.

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Cinar, Umut. "Road Extraction From High Resolution Satellite Images Using Adaptive Boosting With Multi-resolution Analysis." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614650/index.pdf.

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Road extraction from satellite or aerial imagery is a popular topic in remote sensing, and there are many road extraction algorithms suggested by various researches. However, the need of reliable remotely sensed road information still persists as there is no sufficiently robust road extraction algorithm yet. In this study, we explore the road extraction problem taking advantage of the multi-resolution analysis and adaptive boosting based classifiers. That is, we propose a new road extraction algorithm exploiting both spectral and structural features of the high resolution multi-spectral satell

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Gaslikova, Lidia. "High-resolution wave climate analysis in the Helgoland area /." Geesthacht : GKSS-Forschungszentrum, Library, 2006. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015585234&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Hsu, Ching-Ming. "High resolution SIMS analysis using a chemical bevelling technique." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243823.

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Wang, Peng. "High resolution imaging and analysis using aberration-corrected stem." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433775.

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Zamotaeva, Valeriya. "High-resolution FTIR spectra analysis of sulfur dioxide isotopologues." Thesis, Bourgogne Franche-Comté, 2019. http://www.theses.fr/2019UBFCK053.

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Dans cette thèse, nous avons examiné les propriétés spectrales de l’anhydride sulfureux. Les spectres FTIR expérimentaux de nombreux isotopologues du dioxyde de soufre, 32S16O2, 34S16O2, 32S18O2 et 32S16O18O, ont été enregistrés pour la première fois dans les régions des bandes fondamentales, «chaudes», harmoniques et de combinaison. La grande variabilité des conditions expérimentales a permis d’observer et d’identifier pour la première fois des transitions appartenant aux ban¬des ro-vibrationnelles suivantes : 3v2, 3v2 - v2, 2v2 - v2 bandes de 32S16O2 ; 2v2 - v2 bande de 34S16O2 ; v1 + v2, v2

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Aboaba, Olusegun Abiola. "High-resolution multipath channel parameter estimation using wavelet analysis." Thesis, Curtin University, 2014. http://hdl.handle.net/20.500.11937/1271.

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This thesis explores the novel use of wavelet analysis as a high-resolution digital signal processing algorithm for multipath channel parameter estimation. The results obtained from this research indicate that this wavelet-based digital signal processing algorithm overcomes the resolution limitation in conventional high-resolution algorithm. This may provide a more cost-effective means of implementing channel sounding equipments for very high-resolution measurements.

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Falco, Mariachiara. "Analysis of high resolution observations of sunspots fine structures." Doctoral thesis, Università di Catania, 2016. http://hdl.handle.net/10761/3859.

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This Ph.D. thesis deals with the study of the interaction between plasma and magnetic fields on the Sun. Observations acquired during two observing campaigns, one at the Solar Swedish Tower and the other at the Richard B. Dunn Solar Telescope, provided high-resolution data which were used to study the details of some phenomena occurring in the Sun. In particular, this work aims to extend and consolidate our knowledge on the formation and evolution of sunspots observed in the solar photosphere. The first aspect which was investigated concerns the study of the mechanism of the penumbra formation

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Surampudi, Bala Anjani Vasudha. "High-Resolution Modeling of Steel Structures." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1504787210175847.

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Warhola, Paul J. "An analysis of alternative methods to conduct high-resolution activities in a variable-resolution simulation." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1997. http://handle.dtic.mil/100.2/ADA337495.

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Mummery, Gavin Thomas. "Developing a high-resolution bioengineering model for slope stability analysis." Thesis, University of Bristol, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435426.

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Bagnall, Kate. "High spatial resolution analysis of metastable magnesium and titanium alloys." Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337260.

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Akilian, Mireille. "Thin optic surface analysis for high resolution X-ray telescopes." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/34556.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2004.<br>Includes bibliographical references (p. 119-122).<br>The art of glass developed throughout the years has covered artifacts ranging from crude ornaments to high precision optics used in flat panel displays, hard disk drives, and x-ray telescopes. Methods for manufacturing glass sheets and further sheet shaping processes are covered. Future generation, high resolution x-ray telescopes require thin optics with large surface area to thickness ratio and a surface flatness of -500 nm. A novel method utili

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Morgenthal, Guido. "Aerodynamic analysis of structures using high-resolution vortex particle methods." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620717.

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Albratty, Mohammed Mofareh. "Metabonomic analysis of Drosophila mutants using high resolution mass spectrometry." Thesis, University of Strathclyde, 2013. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=18695.

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The availability of fully sequenced genomes of model organisms such as Drosophila and their subsequent annotation has afforded opportunities for reverse genetics in a complex model organism. Metabonomics used as an aid to functional genomics can be used to understand the functions of genes in living systems. Thus metabonomics has been employed to study Drosophila samples extracted from whole animals at different developmental stages or in response to external stimuli or genetic mutation. With unmatched mass resolution, accuracy, and detection sensitivity, linear ion trap - Fourier Transform Or

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Pugh, Andrew. "Elemental analysis of glass optical fibres with high spatial resolution." Thesis, Sheffield Hallam University, 1991. http://shura.shu.ac.uk/20251/.

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The properties of glass optical fibres are very strongly dependent on the elemental concentration profiles of the fibre cores. Core dopants such as germanium define the core refractive index, which in turn defines the manner in which the light is transmitted through the fibre. Erbium in fibre cores can facilitate the operation of fibre lasers and aluminium in turn can control the erbium distribution. The aim of the project described in this thesis was to measure the elemental concentration profiles in a variety of fibre cores using X-ray microanalysis in an electron microscope. Conventional X-

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