Academic literature on the topic 'High risk junctions'

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Journal articles on the topic "High risk junctions"

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Wu, Peijie, Xianghai Meng, Li Song, and Wenze Zuo. "Crash Risk Evaluation and Crash Severity Pattern Analysis for Different Types of Urban Junctions: Fault Tree Analysis and Association Rules Approaches." Transportation Research Record: Journal of the Transportation Research Board 2673, no. 1 (2019): 403–16. http://dx.doi.org/10.1177/0361198118822817.

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Urban junctions usually present significant safety concerns, and the majority of all crashes in urban areas occur in or near junctions. Factors contributing to crash severity at junctions have been explored, but crash risk levels and crash severity patterns of different junction types have hardly been investigated. In order to fill this gap, this study analyzed the safety performance of six junction types and the factors contributing to crash severity, in order to assist city transportation authorities to implement effective countermeasures. Fault tree analysis (FTA) was applied for the risk e
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Stelow, Edward B., Erik A. Dill, Jonathan J. Davick, Michael B. McCabe, and Vanessa M. Shami. "High-Grade Squamous Intraepithelial Lesion of the Gastroesophageal Junction Secondary to High-Risk Human Papillomavirus." American Journal of Clinical Pathology 152, no. 3 (2019): 359–64. http://dx.doi.org/10.1093/ajcp/aqz039.

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ABSTRACT Objectives Although the role of human papillomavirus (HPV) in the development of some carcinomas (eg, anogenital and oropharyngeal squamous cell carcinomas) is nondebatable, there is still significant controversy regarding the relationship of HPV and esophageal squamous cell carcinomas (SCCs). Methods All cases were sampled at or near the gastroesophageal junctions in patients with reflux and/or known Barrett esophagus and appear to have been initially sampled “incidentally.” Patients were all men, aged 56 to 80 years. None had a known history of other HPV-related disease. Results We
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Nta, Samuel Akpan, Erewari Ukoha-Onuoha, Ikpe Jimmy Udom, and Unwana Iniobong Udoumoh. "Concentration and Health Risk Assessment of Heavy Metal in Roadside Soil in Eket, Akwa Ibom State, Nigeria." Asian Soil Research Journal 9, no. 2 (2025): 122–32. https://doi.org/10.9734/asrj/2025/v9i2185.

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Aims: This study determines the heavy metal impacts on roadside soils and its potential health hazards in Eket, Akwa Ibom State, Nigeria. Background: Roads affect natural environment to a large extent because automobile act as line sources of heavy metal pollutants. Emission from heavy traffic have been reported to contain Pb, Cd, Zn and Ni which are present in fuel as anti-knock agent. Heavy metals in the soil can also generate airborne particles and dust which may affect the quality of air. Inhalation of substantial quantities of heavy metal particle over period of time may add to human body
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Storrs, Carina H., and Saul J. Silverstein. "PATJ, a Tight Junction-Associated PDZ Protein, Is a Novel Degradation Target of High-Risk Human Papillomavirus E6 and the Alternatively Spliced Isoform 18 E6*." Journal of Virology 81, no. 8 (2007): 4080–90. http://dx.doi.org/10.1128/jvi.02545-06.

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ABSTRACT The E6 protein from high-risk human papillomavirus types interacts with and degrades several PDZ domain-containing proteins that localize to adherens junctions or tight junctions in polarized epithelial cells. We have identified the tight junction-associated multi-PDZ protein PATJ (PALS1-associated TJ protein) as a novel binding partner and degradation target of high-risk types 16 and 18 E6. PATJ functions in the assembly of the evolutionarily conserved CRB-PALS1-PATJ and Par6-aPKC-Par3 complexes and is critical for the formation of tight junctions in polarized cells. The ability of t
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Wu, Aiming, Mingjing Zhao, Lixia Lou, et al. "Effect of Wenxin Granules on Gap Junction and MiR-1 in Rats with Myocardial Infarction." BioMed Research International 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/3495021.

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Myocardial infarction (MI) patients are at high risk of potential lethal arrhythmia. Gap junction and microRNA-1 (miR-1) are both arrhythmia generating conditions. The present study investigated whether Wenxin Granules (Wenxin-Keli, WXKL) could prevent potential lethal arrhythmia by improving gap junctions and miR-1 following MI. Male Sprague-Dawley rats were divided randomly into control, model, metoprolol, low dose WXKL, and high dose WXKL groups. The MI rat model was created by coronary artery ligation. Treatments were administrated intragastrically to the rats for 4 weeks. Conventional tra
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Nakagawa, Shunsuke, and Jon M. Huibregtse. "Human Scribble (Vartul) Is Targeted for Ubiquitin-Mediated Degradation by the High-Risk Papillomavirus E6 Proteins and the E6AP Ubiquitin-Protein Ligase." Molecular and Cellular Biology 20, no. 21 (2000): 8244–53. http://dx.doi.org/10.1128/mcb.20.21.8244-8253.2000.

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ABSTRACT The high-risk human papillomavirus (HPV) E6 proteins stimulate the ubiquitination and degradation of p53, dependent on the E6AP ubiquitin-protein ligase. Other proteins have also been shown to be targeted for degradation by E6, including hDlg, the human homolog of the Drosophila melanogaster Discs large (Dlg) tumor suppressor. We show here that the human homolog of theDrosophila Scribble (Vartul) (hScrib) tumor suppressor protein is also targeted for ubiquitination by the E6-E6AP complex in vitro and that expression of E6 induces degradation of hScrib in vivo. Characterization of the
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Bischel, Oliver E., Arnold J. Suda, Paul M. Böhm, Therese Bormann, Sebastian Jäger, and Jörn B. Seeger. "Breakage of Tapered Junctions of Modular Stems in Revision Total Hip Arthroplasty—High Incidence in a Consecutive Series of a Single Institution." Bioengineering 10, no. 3 (2023): 341. http://dx.doi.org/10.3390/bioengineering10030341.

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Background: Modularity in revision THA (RTHA) has become accepted during the last three decades. Nevertheless, specific risks of modularity of current revision devices such as breakage of taper junctions occur during follow-up. Data reporting failure rates are predominantly given by the manufacturers but independent data acquisition is missing so far. Questions/Purposes: 1. What time-related risk of breakage of taper junction between neck and body of an established modular revision device can be expected in a consecutive single institutional series and a mid-term follow-up? 2. Are there specif
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Karpenko, Mykola, Olegas Prentkovskis, and Šarūnas Šukevičius. "Research on high-pressure hose with repairing fitting and influence on energy parameter of the hydraulic drive." Eksploatacja i Niezawodnosc - Maintenance and Reliability 24, no. 1 (2021): 25–32. http://dx.doi.org/10.17531/ein.2022.1.4.

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Reliability and maintenance analysis of transport machines hydraulic drives, basically focused to power units: pumps, cylinders etc., without taking in to account junction elements. Therefore, this paper proposes a research analysis on high-pressure hoses and junctions during technical maintenance. Comparative analysis of fluid behavior and energy efficiency inside non-repaired and repaired high-pressure hoses is presented in this research. Theoretical and experimental research results for hydraulic processes inside high-pressure hose is based on the numerical simulations using Navier–Stokes e
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Miyamoto-Mikami, Eri, Hiroshi Kumagai, Naoki Kikuchi, Nobuhiro Kamiya, Naokazu Miyamoto, and Noriyuki Fuku. "eQTL variants in COL22A1 are associated with muscle injury in athletes." Physiological Genomics 52, no. 12 (2020): 588–89. http://dx.doi.org/10.1152/physiolgenomics.00115.2020.

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The myotendinous junction (MTJ) is at high risk of muscle injury, and collagen XXII is strictly expressed at tissue junctions, specifically at the MTJ. We investigated the hypothesis that single-nucleotide polymorphisms (SNPs) related to collagen type XXII α-1 chain gene ( COL22A1) mRNA expression are associated with susceptibility to muscle injury in athletes. History of muscle injury was assessed in 3,320 Japanese athletes using a questionnaire, and two expression quantitative trait loci (eQTL) SNPs for COL22A1 (rs11784270 A/C and rs6577958 T/C) were analyzed using the TaqMan SNP Genotyping
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Shen, Jun, Xiao-Chang Chen, Wang-Jun Li, et al. "Identification of Parkinson’s disease-related pathways and potential risk factors." Journal of International Medical Research 48, no. 10 (2020): 030006052095719. http://dx.doi.org/10.1177/0300060520957197.

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Objective To identify Parkinson’s disease (PD)-associated deregulated pathways and genes, to further elucidate the pathogenesis of PD. Methods Dataset GSE100054 was downloaded from the Gene Expression Omnibus, and differentially expressed genes (DEGs) in PD samples were identified. Functional enrichment analyses were conducted for the DEGs. The top 10 hub genes in the protein–protein interaction (PPI) network were screened out and used to construct a support vector machine (SVM) model. The expression of the top 10 genes was then validated in another dataset, GSE46129, and a clinical patient co
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Dissertations / Theses on the topic "High risk junctions"

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Ander, Fredrik. "Perioperative complications in obese patients : A thesis on risk reducing strategies." Doctoral thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-59411.

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Aspiration of gastric content and delayed or failed intubation are the leading causes of anesthesia-related mortality and morbidity. In the recovery period, airway obstruction with subsequent hypoxia is a relatively common cause of morbidity, and is highly associated to the amount of opioids administered, especially in obese patients. The overall aim of this thesis was to study these risk factors for airway complications and postoperative hypoxia in obese patients, and to evaluate possible strategies for their prevention. In Study I, intubation times and incidence of failed intubation in obese
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Books on the topic "High risk junctions"

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Cohen, Jeffrey A., Justin J. Mowchun, Victoria H. Lawson, and Nathaniel M. Robbins. A 63-Year-Old Male with Severe Flaccid Weakness Post Motor Vehicle Accident. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190491901.003.0009.

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Neuromuscular disorders are important causes of newly acquired weakness in the intensive care unit. Although evaluation usually begins with physical examination findings, these can be compromised in the intensive care unit environment. Therefore, electrodiagnostic study becomes even more important as a tool in localizing weakness to nerve, muscle or neuromuscular junction. Critical illness neuropathy and myopathy occurs in the setting of sepsis and multiple organ failure where sepsis is accompanied by the systemic inflammatory response syndrome. Additional, intensive care unit-specific risk fa
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Book chapters on the topic "High risk junctions"

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Hatipoglu, Abdulkerim. "Brain and Nutrition." In Brain Biochemistry and Its Disease. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359371.7.

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In the current section, the functions of nutrients such as polyunsaturated fatty acids (PUFAs), B group vitamins, calcium, zinc, iron, magnesium in the brain and the effect of diet on neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Amyotrophic Lateral Sclerosis and Multiple Sclerosis are discussed. PUFAs (Linoleic acid, α-Linoleic acid, eicosapentaenoic acid and docosahexaenoic acid), which maintain membrane fluidity necessary for synaptic vesicle fusion and neurotransmitter transmission within neural networks, are essential components of neuronal cell membranes. In older brains,
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Markusen, Ann, Peter Hall, Scott Campbell, and Sabina Deitrick. "Space Mountain: Generals and Boosters Build Colorado Springs." In The Rise Of The Gunbelt. Oxford University PressNew York, NY, 1991. http://dx.doi.org/10.1093/oso/9780195066487.003.0008.

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Abstract Colorado Springs is an unusual site for an aerospace complex. Poised on the abrupt junction of the High Plains and the Front range of the Rockies, flecked in winter by snow on the mesas and backed by the stark flank of Pikes Peak, it is totally unlike typical high-tech sites such as New England, Los Angeles, and Seattle. Yet something remarkable has been happening there. The natural landscape, dramatic as it is, has been overwhelmed by the man-made. Ubiquitous housing subdivisions march across the undulating plains, bringing to mind a vast military encampment-an appropriate image in l
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Kelly, M. J. "Tunnelling phenomena." In Low-Dimensional Semiconductors. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780198517818.003.0008.

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Abstract This is the first of three chapters devoted to the new physics that has been made accessible with the advent of semiconductor multilayers. We shall be concerned with the quantum-mechanical phenomenon that an electron of total energy less than that of a thin potential barrier might not be reflected, as would always happen classically, but rather might pass through the barrier with an exponentially small but finite probability. Tunnelling has been an exploitable phenomenon in solid state physics for some time, and Josephson junction technology makes intimate use of superconducting tunne
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Gasparini, Maurizio, and Paola Galimberti. "Rate control: ablation and device therapy (ablate and pace)." In ESC CardioMed. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0507.

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The atrioventricular junction ablation (AVJA) and pacing method has been a well-known strategy since the 1980s. It is nowadays essentially performed in two groups of patients. First of all, it is indicated in atrial fibrillation (AF) patients who have failed rhythm control with pulmonary vein isolation ablation and different medical rate control strategies. The procedure dramatically reduces symptoms and it is associated with an increase in ejection fraction in patients with AF-induced cardiomyopathy. The second group of patients is represented by heart failure patients with a cardiac resynchr
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Gasparini, Maurizio, and Paola Galimberti. "Rate control: ablation and device therapy (ablate and pace)." In ESC CardioMed. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0507_update_001.

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The atrioventricular junction ablation (AVJA) and pacing method has been a well-known strategy since the 1980s. It is nowadays essentially performed in two groups of patients. First of all, it is indicated in atrial fibrillation (AF) patients who have failed rhythm control with pulmonary vein isolation ablation and different medical rate control strategies. The procedure dramatically reduces symptoms and it is associated with an increase in ejection fraction in patients with AF-induced cardiomyopathy. The second group of patients is represented by heart failure patients with a cardiac resynchr
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Kelly, M. J. "Hot electron phenomena." In Low-Dimensional Semiconductors. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780198517818.003.0007.

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Abstract Much interesting physics, and most device applications, are associated with carriers that have been excited in some manner to have an energy well in excess of their energy when in thermal equilibrium. In some cases the carriers behave in a manner that can be associated with an elevated temperature, giving rise to the name hot carrier. The name is used more widely to refer to any highly excited carrier. We discussed the velocity-field curves for bulk Si and GaAs in Chapter 1, Section 1.7. We described the transition from Ohm’s law behaviour at low electric fields, where the carriers ar
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Apaydın, Umut, and Devrim Can Saraç. "Current Exercise Approaches in Lumbosacral Pathologies." In Current Exercise Approaches in Orthopedic Disorders: A handbook for rehabilitation professionals. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358770.3.

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The lumbosacral region, situated at the lower end of the spine, consists of the lumbar vertebrae and the sacrum. This area serves as a critical junction between the upper body and the pelvis, bearing much of the body's weight and facilitating a wide range of movements. Given its structural and functional responsibilities, the lumbosacral region is particularly susceptible to various disorders and injuries. Factors such as aging, degenerative changes, poor posture, and physical strain can lead to conditions that significantly impair mobility and cause chronic pain. Additionally, this region hou
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Toueg Charles-William, Mac-Thiong Jean-Marc, Grimard Guy, Parent Stefan, Poitras Benoit, and Labelle Hubert. "Prevalence of Spondylolisthesis in a Population of Gymnasts." In Studies in Health Technology and Informatics. IOS Press, 2010. https://doi.org/10.3233/978-1-60750-573-0-132.

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Spondylolysis occurs in 6 % of the general population. Of these, approximately 75% will develop spondylolisthesis. According to multiple studies, an increased prevalence of spondylolysis and spondylolisthesis exists in groups of athletes practicing certain sports such as gymnastics. In the literature, prevalence of spondylolisthesis in gymnasts can reach up to 40 to 50 %. However, the specific risk factors associated with the development of spondylolisthesis in gymnasts are not known. The main purpose of this study was to evaluate the prevalence of spondylolysis and spondylolisthesis in a popu
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Conference papers on the topic "High risk junctions"

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AlRashdi, Majid, and Mustapha Azzouzi. "Data-Driven Approach to Risk Analysis of PDO-Owned Junctions." In SPE Conference at Oman Petroleum & Energy Show. SPE, 2025. https://doi.org/10.2118/224866-ms.

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Abstract This study proposes the enhancement of road junction safety by conducting a risk analysis based on available data (Reactive approach) to recognize locations that could present the most road crash-prone sites with relation to frequency and severity. Accordingly, this study classifies risks at junctions in a comprehensive manner based on MVI (Motor vehicle incident) data from 2020 to 2024 with a view toward ranking the sites for prioritizing those that most need intervention with the best optimization of resources that could ensure more effective improvements related to road casualty re
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Shor, Roman J., An Mai, Athena E. Manolakos, et al. "Enabling High Performance Multi-Lateral Wells: Current Technologies and Gaps." In SPE Canadian Energy Technology Conference and Exhibition. SPE, 2023. http://dx.doi.org/10.2118/212731-ms.

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Abstract This paper presents the current state of the industry in multilateral wells (ML) and presents the key findings from a broad literature review and two knowledge sharing workshops hosted by the University of Calgary and the Clean Resource Innovation Network (CRIN) in late 2021 and early 2022. The technology to deliver ML wells is mature and has been demonstrated across thousands of wellbores around the world. Evaluation, characterization, and control of flows in ML wells is also possible using available technology, however, it is expensive and may be cost prohibitive. Modelling and opti
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Carlson, Andrew, Chidambaram Narayanan, Djamel Lakehal, Timo Hermonen, Noora Jokinen, and Juho Ikävalko. "CFD Study of Cooking Liquor Blow for Piping Thrust Force and Risk of Condensation Hydraulic Shock." In ASME 2022 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/pvp2022-79373.

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Abstract This study is an interesting industrial case study for the application of a validated flashing and hydraulic shock modelling approach to the safety and design of a reactor blow line. The maximum flow rate is important for sizing of downstream components. The high pressure of the blow and flashing of the liquid can result in significant forces on pipe bends and other geometrical features. Analysis and prediction of such forces are of importance for the structural design and anchoring of the piping. Another concern for a liquid blow under high pressure is the potential for condensation-
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Rudolph, Luciana, Richard Trewin, Robert Buettner, and Thomas Fuchs. "Development and Validation of an Effective Screening Process for Thermal-Hydraulic Phenomena With Relevance to Thermal Loads in Nuclear Power Plants Piping System." In ASME 2024 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2024. http://dx.doi.org/10.1115/pvp2024-123405.

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Abstract In nuclear power plants (NPP), there is a series of pipe junctions with a main pipe connected to closed-end branch pipe, in which degradation due to high cycle thermal fatigue potentially can occur. The identification of those locations in NPP piping systems is highly important to decide on mitigation activities. Thermal-fatigue cracking due to thermal stresses in a branch pipe occurs at the fluctuating boundary created by the turbulent penetration of hot liquid from the main pipe into the nominally cold liquid of the branch line. The branch flow is nominally stagnant due to, e.g., a
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Almasri, Abdulrakeeb, Adnan Alsadeh, Arra'uf Shukor, and Abdullah Abdulhalim. "From Obstacles to Opportunities: Unlocking the Power of Customized Multilateral Solutions." In ADIPEC. SPE, 2024. http://dx.doi.org/10.2118/222504-ms.

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Abstract The continuous advancement of multilateral completion technology has significantly transformed the oil and gas sector. It has enabled access to reservoirs, resulting in a substantial influence on production capacity. However, the challenges faced when drilling a multilateral well need to be understood and addressed. This paper will outline such challenges and provide insights into how these were overcome to achieve the desired goals. The efficacy of the Multilateral selective lateral access window has been demonstrated over the past few decades. It has allowed successful identificatio
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Robbins, C. J., S. Fotios, J. Uttley, and R. Rowe. "OPTIMISING ROAD LIGHTING TO REDUCE ROAD TRAFFIC CRASHES." In CIE 2021 Conference. International Commission on Illumination, CIE, 2021. http://dx.doi.org/10.25039/x48.2021.op32.

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Pedestrians and motorcyclists are vulnerable road users, being over represented in road traffic collisions (RTCs). One assumed benefit of road lighting is a reduction in RTCs after dark by countering the impairment to the visual detection of hazards that occur after dark. One way to optimise the use of road lighting is to light only those sections of road where light level, and hence visibility, is an important factor. The current study used change in ambient light level on RTCs to investigate those situations where improved vision is likely to have significant impact, and therefore the situat
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Amini, Elham, Ruslan Muydinov, Bernd Szyszka, and Christian Boit. "Backside Protection Structure for Security Sensitive ICs." In ISTFA 2017. ASM International, 2017. http://dx.doi.org/10.31399/asm.cp.istfa2017p0279.

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Abstract Modern integrated circuits (ICs) are in permanent risk of hardware attacks on sensitive data. But, proper and affordable protection of the IC backside against Focused Ion Beam (FIB) and optical fault injection attacks is missing. In this work, we investigate a patent [1] that uses p-n junctions as light emitters (forward bias) and detectors. We improved the backside detection mechanism presented in the patent by developing a test structure and adding an optically active layer on the backside as protective element to detect an attacked backside with electrical signals in the IC. The an
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Dai, Ling, Jinchang Hu, Yang Yang, Fuchang Lin, and Qin Zhang. "Research on transient junction temperature rise of pulse thyristor." In 2016 IEEE International Power Modulator and High Voltage Conference (IPMHVC). IEEE, 2016. http://dx.doi.org/10.1109/ipmhvc.2016.8012911.

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Duprée, A., H. Ehlken, T. Rösch, et al. "Laparoscopic Lymph Node Sampling for Patients with High-Risk Early Esophagogastric Junction Cancer resected Endoscopically." In Viszeralmedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1695120.

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Okladnikova, Elena V., and Andrey V. Lyapustin. "Inspection of the enclosing structures of an industrial facility building in the conditions of the Far East." In Agro-industrial complex: problems and prospects of development. Far Eastern State Agrarian University, 2024. https://doi.org/10.22450/978-5-9642-0635-4-156-161.

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The article considers the results of a thermal imaging survey of threelayer enclosing structures of a high-rise building, an analysis is carried out at various junctions. The influence of thermal engineering characteristics of enclosing structures on the energy efficiency level of the facility is investigated.
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Reports on the topic "High risk junctions"

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Gisladottir, Viktoria, Amanda Kolker, Zachary Zody, and Ian Warren. Phase I geothermal opportunities assessment of the Delta Junction area, Alaska. Engineer Research and Development Center (U.S.), 2023. http://dx.doi.org/10.21079/11681/47766.

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To enhance energy resilience at military installations in Interior Alaska, we are exploring geothermal energy, which harvests Earth’s heat to provide thermal energy, electricity, or both. Parts of Interior Alaska have high subsurface heat flow, likely related to high-heat-producing granites. While electric load is usually the focus of energy resilience; in cold regions, the thermal load dominates energy demand, and operations can be sensitive to it. A local geothermal energy source enhances energy resilience by providing baseload energy and lessening supply chain demand. Geothermal energy tech
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