Log in

Relevant bibliographies by topics / High-throughput polymer screening / Journal articles

To see the other types of publications on this topic, follow the link: High-throughput polymer screening.

Journal articles on the topic 'High-throughput polymer screening'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'High-throughput polymer screening.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Revia, Richard A., Brandon Wagner, Matthew James, and Miqin Zhang. "High-Throughput Dispensing of Viscous Solutions for Biomedical Applications." Micromachines 13, no. 10 (2022): 1730. http://dx.doi.org/10.3390/mi13101730.

Full text

Abstract:

Cells cultured in three-dimensional scaffolds express a phenotype closer to in vivo cells than cells cultured in two-dimensional containers. Natural polymers are suitable materials to make three-dimensional scaffolds to develop disease models for high-throughput drug screening owing to their excellent biocompatibility. However, natural polymer solutions have a range of viscosities, and none of the currently available liquid dispensers are capable of dispensing highly viscous polymer solutions. Here, we report the development of an automated scaffold dispensing system for rapid, reliable, and h

APA, Harvard, Vancouver, ISO, and other styles

2

St. John, Peter C., Caleb Phillips, Travis W. Kemper, et al. "Message-passing neural networks for high-throughput polymer screening." Journal of Chemical Physics 150, no. 23 (2019): 234111. http://dx.doi.org/10.1063/1.5099132.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Zapata, Pedro, Pratyay Basak, and J. Carson Meredith. "High-throughput screening of ionic conductivity in polymer membranes." Electrochimica Acta 54, no. 15 (2009): 3899–909. http://dx.doi.org/10.1016/j.electacta.2009.02.009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Low, John J., Annabelle I. Benin, Paulina Jakubczak, Jennifer F. Abrahamian, Syed A. Faheem, and Richard R. Willis. "Virtual High Throughput Screening Confirmed Experimentally: Porous Coordination Polymer Hydration." Journal of the American Chemical Society 131, no. 43 (2009): 15834–42. http://dx.doi.org/10.1021/ja9061344.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Tweedie, C. A., D. G. Anderson, R. Langer, and K. J. Van Vliet. "Combinatorial Material Mechanics: High-Throughput Polymer Synthesis and Nanomechanical Screening." Advanced Materials 17, no. 21 (2005): 2599–604. http://dx.doi.org/10.1002/adma.200501142.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Jakubowicz, Ignacy, and Nazdaneh Yarahmadi. "Development of Polymer Matrix Clay Nanocomposites for Industrial Applications Using High Throughput Methods." Solid State Phenomena 151 (April 2009): 35–42. http://dx.doi.org/10.4028/www.scientific.net/ssp.151.35.

Full text

Abstract:

The development of polymer-layered silicate nanocomposites (PNCs) includes a long list of different possible components such as polymers, nano-additives, and co-additives, together with surface chemistry and various processing conditions. This involves the investigation of a large number of parameters that influence PNC performance. Consequently, fairly extensive research and development work is necessary, and this constitutes an obstacle in the commercialization of nanotechnology. This paper, which is based on experience from research and development for an industrial application, presents a

APA, Harvard, Vancouver, ISO, and other styles

7

Sarkar, J., and A. Kumar. "Thermo-responsive polymer aided spheroid culture in cryogel based platform for high throughput drug screening." Analyst 141, no. 8 (2016): 2553–67. http://dx.doi.org/10.1039/c6an00356g.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Marufu, Michell, Johanna Schwartz, and Jayvic Jimenez. "Studying-Polymers-on-a-Chip (SPOC): Automated, High-Throughput Screening of Increased Ionic Conductivity Polymer Electrolytes." ECS Meeting Abstracts MA2024-02, no. 10 (2024): 5046. https://doi.org/10.1149/ma2024-02105046mtgabs.

Full text

Abstract:

Advancements of solid polymer electrolytes are critical for the next generation of lithium-ion batteries within our highly energy-dependent society. Research techniques that speed up materials discovery are crucial to meet this need. Towards this end we have invented a Studying-Polymers-On-a-Chip (SPOC) platform that integrates active mixing direct ink-write 3D printing, in-situ impedance characterization and machine learning experimental planning systems. Collectively, this technology enables automated high-throughput screening of increased ionic conductivity polymer electrolytes. We report a

APA, Harvard, Vancouver, ISO, and other styles

9

Haven, Joris J., Evelien Baeten, Jonathan Claes, Joke Vandenbergh, and Tanja Junkers. "High-throughput polymer screening in microreactors: boosting the Passerini three component reaction." Polymer Chemistry 8, no. 19 (2017): 2972–78. http://dx.doi.org/10.1039/c7py00360a.

Full text

Abstract:

The Passerini three-component reaction (Passerini-3CR) has been studied via on-line microreactor/electrospray ionisation mass spectrometry (MRT/ESI-MS) reaction monitoring to demonstrate the high-throughput screening potential of microreactors for macromolecular design.

APA, Harvard, Vancouver, ISO, and other styles

10

Chen, Fang-Chung. "Virtual Screening of Conjugated Polymers for Organic Photovoltaic Devices Using Support Vector Machines and Ensemble Learning." International Journal of Polymer Science 2019 (March 31, 2019): 1–7. http://dx.doi.org/10.1155/2019/4538514.

Full text

Abstract:

Herein, we report virtual screening of potential semiconductor polymers for high-performance organic photovoltaic (OPV) devices using various machine learning algorithms. We particularly focus on support vector machine (SVM) and ensemble learning approaches. We found that the power conversion efficiencies of the device prepared with the polymer candidates can be predicted with their structure fingerprints as the only inputs. In other words, no preliminary knowledge about material properties was required. Additionally, the predictive performance could be further improved by “blending” the resul

APA, Harvard, Vancouver, ISO, and other styles

11

Carson Meredith, J., Alamgir Karim, and Eric J. Amis. "Combinatorial Methods for Investigations in Polymer Materials Science." MRS Bulletin 27, no. 4 (2002): 330–35. http://dx.doi.org/10.1557/mrs2002.101.

Full text

Abstract:

AbstractWe review recent advances in the development of combinatorial methods for polymer characterization. Applied to materials research, combinatorial methodologies allow efficient testing of structure–property hypotheses (fundamental characterization) as well as accelerated development of new materials (materials discovery). Recent advances in library preparation and high-throughput screening have extended combinatorial methods to a wide variety of phenomena encountered in polymer processing. We first present techniques for preparing continuous-gradient polymer “libraries” with controlled v

APA, Harvard, Vancouver, ISO, and other styles

12

Krüger, Harald R., Gregor Nagel, Stefanie Wedepohl, and Marcelo Calderón. "Dendritic polymer imaging systems for the evaluation of conjugate uptake and cleavage." Nanoscale 7, no. 9 (2015): 3838–44. http://dx.doi.org/10.1039/c4nr04467c.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Bedwell, Thomas S., Nadeem Anjum, Yifeng Ma, et al. "New protocol for optimisation of polymer composition for imprinting of peptides and proteins." RSC Advances 9, no. 48 (2019): 27849–55. http://dx.doi.org/10.1039/c9ra05009d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Zhou, Yang, Gillian Pereira, Yuanzhang Tang, Matthew James, and Miqin Zhang. "3D Porous Scaffold-Based High-Throughput Platform for Cancer Drug Screening." Pharmaceutics 15, no. 6 (2023): 1691. http://dx.doi.org/10.3390/pharmaceutics15061691.

Full text

Abstract:

Natural polymer-based porous scaffolds have been investigated to serve as three-dimensional (3D) tumor models for drug screening owing to their structural properties with better resemblance to human tumor microenvironments than two-dimensional (2D) cell cultures. In this study, a 3D chitosan–hyaluronic acid (CHA) composite porous scaffold with tunable pore size (60, 120 and 180 µm) was produced by freeze-drying and fabricated into a 96-array platform for high-throughput screening (HTS) of cancer therapeutics. We adopted a self-designed rapid dispensing system to handle the highly viscous CHA p

APA, Harvard, Vancouver, ISO, and other styles

15

Hammad, Moamen, Wei Rao, James G. W. Smith, et al. "Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion." Biomaterials Science 4, no. 9 (2016): 1381–91. http://dx.doi.org/10.1039/c6bm00214e.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Quinn, Harley J., Wenlu Wang, Joerg G. Werner, and Keith A. Brown. "(Invited) accelerating Polymer Discovery for Multifunctional Polymer Thin Films: High-Throughput Characterization." ECS Meeting Abstracts MA2023-01, no. 34 (2023): 1886. http://dx.doi.org/10.1149/ma2023-01341886mtgabs.

Full text

Abstract:

Identifying new formulations of polymers that have multiple highly tuned properties is a grand challenge of materials development. This is especially important in polymer thin film devices where several distinct transport properties must be controlled. For instance, solid-state battery electrolyte materials must be conductive to ions, but remain electronically insulating. In order to achieve the materials advances needed to transform the use of such polymer thin films, new paradigms of accelerated materials development are needed. In this talk, we discuss our recent efforts to accelerate the d

APA, Harvard, Vancouver, ISO, and other styles

17

Chen, Guang, Lei Tao, and Ying Li. "Predicting Polymers’ Glass Transition Temperature by a Chemical Language Processing Model." Polymers 13, no. 11 (2021): 1898. http://dx.doi.org/10.3390/polym13111898.

Full text

Abstract:

We propose a chemical language processing model to predict polymers’ glass transition temperature (Tg) through a polymer language (SMILES, Simplified Molecular Input Line Entry System) embedding and recurrent neural network. This model only receives the SMILES strings of a polymer’s repeat units as inputs and considers the SMILES strings as sequential data at the character level. Using this method, there is no need to calculate any additional molecular descriptors or fingerprints of polymers, and thereby, being very computationally efficient. More importantly, it avoids the difficulties to gen

APA, Harvard, Vancouver, ISO, and other styles

18

Xia, Wensheng, Frauke Rininsland, Shannon K. Wittenburg, et al. "Applications of Fluorescent Polymer Superquenching to High Throughput Screening Assays for Protein Kinases." ASSAY and Drug Development Technologies 2, no. 2 (2004): 183–92. http://dx.doi.org/10.1089/154065804323056521.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Okagbare, Paul I., and Steven Allan Soper. "Polymer-based dense fluidic networks for high throughput screening with ultrasensitive fluorescence detection." ELECTROPHORESIS 31, no. 18 (2010): 3074–82. http://dx.doi.org/10.1002/elps.201000209.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Kranenburg, Johannes M., Catherine A. Tweedie, Krystyn J. van Vliet, and Ulrich S. Schubert. "Challenges and Progress in High-Throughput Screening of Polymer Mechanical Properties by Indentation." Advanced Materials 21, no. 35 (2009): 3551–61. http://dx.doi.org/10.1002/adma.200803538.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Sui, Shuo, Anne Mulichak, Raviraj Kulathila, et al. "A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening." Journal of Applied Crystallography 54, no. 4 (2021): 1034–46. http://dx.doi.org/10.1107/s1600576721004155.

Full text

Abstract:

A novel capillary-based microfluidic strategy to accelerate the process of small-molecule-compound screening by room-temperature X-ray crystallography using protein crystals is reported. The ultra-thin microfluidic devices are composed of a UV-curable polymer, patterned by cleanroom photolithography, and have nine capillary channels per chip. The chip was designed for ease of sample manipulation, sample stability and minimal X-ray background. 3D-printed frames and cassettes conforming to SBS standards are used to house the capillary chips, providing additional mechanical stability and compatib

APA, Harvard, Vancouver, ISO, and other styles

22

Celiz, A. D., J. G. W. Smith, A. K. Patel, et al. "Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture." Biomater. Sci. 2, no. 11 (2014): 1604–11. http://dx.doi.org/10.1039/c4bm00054d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Michelmore, Andrew, Lauren Clements, David A. Steele, Nicolas H. Voelcker, and Endre J. Szili. "Gradient Technology for High-Throughput Screening of Interactions between Cells and Nanostructured Materials." Journal of Nanomaterials 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/839053.

Full text

Abstract:

We present a novel substrate suitable for the high-throughput analysis of cell response to variations in surface chemistry and nanotopography. Electrochemical etching was used to produce silicon wafers with nanopores between 10 and 100 nm in diameter. Over this substrate and flat silicon wafers, a gradient film ranging from hydrocarbon to carboxylic acid plasma polymer was deposited, with the concentration of surface carboxylic acid groups varying between 0.7 and 3% as measured by XPS. MG63 osteoblast-like cells were then cultured on these substrates and showed greatest cell spreading and adhe

APA, Harvard, Vancouver, ISO, and other styles

24

Eslamibidgoli, Mohammad J., Fabian P. Tipp, Jenia Jitsev, Jasna Jankovic, Michael H. Eikerling, and Kourosh Malek. "Convolutional neural networks for high throughput screening of catalyst layer inks for polymer electrolyte fuel cells." RSC Advances 11, no. 51 (2021): 32126–34. http://dx.doi.org/10.1039/d1ra05324h.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Ahl, Louise I., Olwen M. Grace, Henriette L. Pedersen, William G. T. Willats, Bodil Jørgensen, and Nina Rønsted. "Analyses of Aloe Polysaccharides Using Carbohydrate Microarray Profiling." Journal of AOAC INTERNATIONAL 101, no. 6 (2018): 1720–28. http://dx.doi.org/10.5740/jaoacint.18-0120.

Full text

Abstract:

Abstract Background: As the popularity of Aloe vera extracts continues to rise, a desire to fully understand the individual polymer components of the leaf mesophyll, their relation to one another, and the effects they have on the human body are increasing. Polysaccharides present in the leaf mesophyll have been identified as the components responsible for the biological activities of A. vera, and they have been widely studied in the past decades. However, the commonly used methods do not provide the desired platform to conduct large comparative studies of polysaccharide compositions, as most o

APA, Harvard, Vancouver, ISO, and other styles

26

Wang, Mao, Qisong Xu, Hongjian Tang, and Jianwen Jiang. "Machine Learning-Enabled Prediction and High-Throughput Screening of Polymer Membranes for Pervaporation Separation." ACS Applied Materials & Interfaces 14, no. 6 (2022): 8427–36. http://dx.doi.org/10.1021/acsami.1c22886.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Martin, Richard L., Cory M. Simon, Berend Smit, and Maciej Haranczyk. "In silico Design of Porous Polymer Networks: High-Throughput Screening for Methane Storage Materials." Journal of the American Chemical Society 136, no. 13 (2014): 5006–22. http://dx.doi.org/10.1021/ja4123939.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Meier, Michael A. R., Richard Hoogenboom, and Ulrich S. Schubert. "Combinatorial Methods, Automated Synthesis and High-Throughput Screening in Polymer Research: The Evolution Continues." Macromolecular Rapid Communications 25, no. 1 (2004): 21–33. http://dx.doi.org/10.1002/marc.200300147.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Hoogenboom, Richard, Michael A. R. Meier, and Ulrich S. Schubert. "Combinatorial Methods, Automated Synthesis and High-Throughput Screening in Polymer Research: Past and Present." Macromolecular Rapid Communications 24, no. 1 (2003): 15–32. http://dx.doi.org/10.1002/marc.200390013.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Su, Xiaojing, Edmond W. K. Young, Heather A. S. Underkofler, Timothy J. Kamp, Craig T. January, and David J. Beebe. "Microfluidic Cell Culture and Its Application in High-Throughput Drug Screening." Journal of Biomolecular Screening 16, no. 1 (2010): 101–11. http://dx.doi.org/10.1177/1087057110386218.

Full text

Abstract:

Evaluation of drug cardiotoxicity is essential to the safe development of novel pharmaceuticals. Assessing a compound’s risk for prolongation of the surface electrocardiographic QT interval and hence risk for life-threatening arrhythmias is mandated before approval of nearly all new pharmaceuticals. QT prolongation has most commonly been associated with loss of current through hERG ( human ether-a-go-go related gene) potassium ion channels due to direct block of the ion channel by drugs or occasionally by inhibition of the plasma membrane expression of the channel protein. To develop an effici

APA, Harvard, Vancouver, ISO, and other styles

31

Zapata, Pedro, Jing Su, Andrés J. García, and J. Carson Meredith. "Quantitative High-Throughput Screening of Osteoblast Attachment, Spreading, and Proliferation on Demixed Polymer Blend Micropatterns." Biomacromolecules 8, no. 6 (2007): 1907–17. http://dx.doi.org/10.1021/bm061134t.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Potyrailo, Radislav A., Andrew M. Leach, and Cheryl M. Surman. "Multisize CdSe Nanocrystal/Polymer Nanocomposites for Selective Vapor Detection Identified from High-Throughput Screening Experimentation." ACS Combinatorial Science 14, no. 3 (2012): 170–78. http://dx.doi.org/10.1021/co200112s.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Kniep, Carina S. "1st DPI Workshop on Automated Synthesis and High-Throughput Screening in Polymer and Materials Research." Macromolecular Rapid Communications 23, no. 10-11 (2002): 643. http://dx.doi.org/10.1002/1521-3927(20020701)23:10/11<643::aid-marc643>3.0.co;2-u.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Lohoff, Andreas Schulze, Leif Poggemann, Marcelo Carmo, Martin Müller, and Detlef Stolten. "Enabling High Throughput Screening of Polymer Electrolyte Membrane (PEM) Water Electrolysis Components via Miniature Test Cells." Journal of The Electrochemical Society 163, no. 11 (2016): F3153—F3157. http://dx.doi.org/10.1149/2.0211611jes.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Meier, Michael A. R., and Ulrich S. Schubert. "Integration of MALDI-TOFMS as high-throughput screening tool into the workflow of combinatorial polymer research." Review of Scientific Instruments 76, no. 6 (2005): 062211. http://dx.doi.org/10.1063/1.1906123.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Suzuki, Takahiro, Kanae Sato, Tomohiro Seki, and Toshinobu Seki. "Study of Polymer Nanofilms Using for High-Throughput Screening in the Development of Transdermal Therapeutic System." Chemical and Pharmaceutical Bulletin 70, no. 12 (2022): 868–75. http://dx.doi.org/10.1248/cpb.c22-00457.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Tweedie, C. A., D. G. Anderson, R. Langer, and K. J. Van Vliet. "Cover Picture: Combinatorial Material Mechanics: High-Throughput Polymer Synthesis and Nanomechanical Screening (Adv. Mater. 21/2005)." Advanced Materials 17, no. 21 (2005): NA. http://dx.doi.org/10.1002/adma.200590109.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Pluntze, Amanda, Scott Beecher, Maria Anderson, Dillon Wright, and Deanna Mudie. "Material-Sparing Feasibility Screening for Hot Melt Extrusion." Pharmaceutics 16, no. 1 (2024): 76. http://dx.doi.org/10.3390/pharmaceutics16010076.

Full text

Abstract:

Hot melt extrusion (HME) offers a high-throughput process to manufacture amorphous solid dispersions. A variety of experimental and model-based approaches exist to predict API solubility in polymer melts, but these methods are typically aimed at determining the thermodynamic solubility and do not take into account kinetics of dissolution or the associated degradation of the API during thermal processing, both of which are critical considerations in generating a successful amorphous solid dispersion by HME. This work aims to develop a material-sparing approach for screening manufacturability of

APA, Harvard, Vancouver, ISO, and other styles

39

Taresco, Vincenzo, Iria Louzao, David Scurr, et al. "Rapid Nanogram Scale Screening Method of Microarrays to Evaluate Drug–Polymer Blends Using High-Throughput Printing Technology." Molecular Pharmaceutics 14, no. 6 (2017): 2079–87. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00182.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Markovitz-Bishitz, Yael, Yishay Tauber, Elena Afrimzon, et al. "A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids." Biomaterials 31, no. 32 (2010): 8436–44. http://dx.doi.org/10.1016/j.biomaterials.2010.07.050.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Hezi-Yamit, Ayala, Carol Sullivan, Jennifer Wong, et al. "Novel High Throughput Polymer Biocompatibility Screening Designed for SAR (Structure-Activity Relationship): Application for Evaluating Polymer Coatings for Cardiovascular Drug-Eluting Stents." Combinatorial Chemistry & High Throughput Screening 12, no. 7 (2009): 664–76. http://dx.doi.org/10.2174/138620709788923674.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Vahdatkhah, Parisa, Yasin Zolfaghar, and Eric McCalla. "Adapting High-Throughput Synthesis for Aggressively Air-Sensitive Halide Solid Electrolytes." ECS Meeting Abstracts MA2025-01, no. 3 (2025): 197. https://doi.org/10.1149/ma2025-013197mtgabs.

Full text

Abstract:

The advancement of solid-state batteries (SSBs) has been hindered by the limitations of existing solid-state electrolytes (SSEs), including high-temperature sintering of oxides, air instability of sulfides, and narrow electrochemical windows of polymer electrolytes. To address these challenges, we explore the development of a novel halide Li+ superionic conductor, Li3InCl6, synthesized using a high-throughput approach in an aqueous medium. This innovative electrolyte demonstrates favorable ionic conductivity and resilience, with the ability to recover conductivity after exposure to water. When

APA, Harvard, Vancouver, ISO, and other styles

43

Eslamibidgoli, Mohammad J., Kourosh Malek, and Michael Eikerling. "Autonomous Image Analysis to Accelerate the Discovery and Integration of Energy Materials." ECS Meeting Abstracts MA2022-01, no. 45 (2022): 1908. http://dx.doi.org/10.1149/ma2022-01451908mtgabs.

Full text

Abstract:

Accelerating the development of electrochemical energy devices (e.g., batteries, fuel cells, electrolysis cells) is pivotal for the transition towards a green and sustainable energy economy. A significant proportion of development efforts in this realm is relying on new functional materials as electrocatalytically active media, ionic media, porous transport media, or multi-functional electrodes. Experimental materials research harnesses a broad spectrum of imaging and visualization methods, based on modern spectroscopy, microscopy, and scattering techniques. These techniques are utilized to qu

APA, Harvard, Vancouver, ISO, and other styles

44

Rinkenauer, Alexandra C., Antje Vollrath, Anja Schallon, et al. "Parallel High-Throughput Screening of Polymer Vectors for Nonviral Gene Delivery: Evaluation of Structure–Property Relationships of Transfection." ACS Combinatorial Science 15, no. 9 (2013): 475–82. http://dx.doi.org/10.1021/co400025u.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Wright, Leah, Timothy J. Barnes, Paul Joyce, and Clive A. Prestidge. "Optimisation of a High-Throughput Model for Mucus Permeation and Nanoparticle Discrimination Using Biosimilar Mucus." Pharmaceutics 14, no. 12 (2022): 2659. http://dx.doi.org/10.3390/pharmaceutics14122659.

Full text

Abstract:

High-throughput permeation models are essential in drug development for timely screening of new drug and formulation candidates. Nevertheless, many current permeability assays fail to account for the presence of the gastrointestinal mucus layer. In this study, an optimised high-throughput mucus permeation model was developed employing a highly biorelevant mucus mimic. While mucus permeation is primarily conducted in a simple mucin solution, the complex chemistry, nanostructure and rheology of mucus is more accurately modelled by a synthetic biosimilar mucus (BSM) employing additional protein,

APA, Harvard, Vancouver, ISO, and other styles

46

Silbert, Liron, Izek Ben Shlush, Elena Israel, Angel Porgador, Sofiya Kolusheva, and Raz Jelinek. "Rapid Chromatic Detection of Bacteria by Use of a New Biomimetic Polymer Sensor." Applied and Environmental Microbiology 72, no. 11 (2006): 7339–44. http://dx.doi.org/10.1128/aem.01324-06.

Full text

Abstract:

ABSTRACT We present a new platform for visual and spectroscopic detection of bacteria. The detection scheme is based on the interaction of membrane-active compounds secreted by bacteria with agar-embedded nanoparticles comprising phospholipids and the chromatic polymer polydiacetylene (PDA). We demonstrate that PDA undergoes dramatic visible blue-to-red transformations together with an intense fluorescence emission that are induced by molecules released by multiplying bacteria. The chromatic transitions are easily identified by the naked eye and can also be recorded by conventional high-throug

APA, Harvard, Vancouver, ISO, and other styles

47

Sundstrom, Eric R., and Craig S. Criddle. "Optimization of Methanotrophic Growth and Production of Poly(3-Hydroxybutyrate) in a High-Throughput Microbioreactor System." Applied and Environmental Microbiology 81, no. 14 (2015): 4767–73. http://dx.doi.org/10.1128/aem.00025-15.

Full text

Abstract:

ABSTRACTProduction of poly(3-hydroxybutyrate) (P3HB) from methane has economic and environmental advantages over production by agricultural feedstock. Identification of high-productivity strains and optimal growth conditions is critical to efficient conversion of methane to polymer. Current culture conditions, including serum bottles, shake flasks, and agar plates, are labor-intensive and therefore insufficient for systematic screening and isolation. Gas chromatography, the standard method for analysis of P3HB content in bacterial biomass, is also incompatible with high-throughput screening. G

APA, Harvard, Vancouver, ISO, and other styles

48

Stankewicz, Casey, and Frauke H. Rininsland. "A Robust Screen for Inhibitors and Enhancers of Phosphoinositide-3 Kinase (PI3K) Activities by Ratiometric Fluorescence Superquenching." Journal of Biomolecular Screening 11, no. 4 (2006): 413–22. http://dx.doi.org/10.1177/1087057106286402.

Full text

Abstract:

Aberrant regulation of phosphoinositide 3-kinase (PI3K) activity is implicated in various diseases such as cancer and diabetes. Thus, high-throughput screening (HTS) of small-molecule inhibitors for PI3 kinases is an appealing strategy for drug development. Despite the attractiveness of lipid kinases as drug targets, screening for inhibitors for PI3K activities has been hampered by limited assay formats adaptable for HTS. The authors describe a homogeneous, direct, and nonradioactive assay for highly sensitive detection of PI3Kα, β, δ, and γ activities, which is suitable for HTS. The assay is

APA, Harvard, Vancouver, ISO, and other styles

49

Krishnamoorti, Ramanan. "Strategies for Dispersing Nanoparticles in Polymers." MRS Bulletin 32, no. 4 (2007): 341–47. http://dx.doi.org/10.1557/mrs2007.233.

Full text

Abstract:

AbstractControlling the dispersion of nanoparticles in polymeric matrices is the most significant impediment in the development of high-perform ance polymer nanocomposite ma te rials and results primarily from the strong interpar ticle interactions between the nanopar ticles. This review examines the theoretical and experimental strategies employed in developing appropriate chemical and physical methods to achieve controlled dispersion of nanopar ticles. Methods to characterize the state of dispersion, including force and electron micros copy, and scattering, electrical, and mechanical spectro

APA, Harvard, Vancouver, ISO, and other styles

50

Sun, Chung-Ming. "Recent Advances in Liquid-Phase Combinatorial Chemistry." Combinatorial Chemistry & High Throughput Screening 2, no. 6 (1999): 299–318. http://dx.doi.org/10.2174/1386207302666220205231100.

Full text

Abstract:

In combination with high throughput screening, combinatorial organic synthesis of large numbers of pharmaceutically interesting compounds may revolutionize the drug discovery process. Although combinatorial organic synthesis on solid supports is a useful approach, several groups are focusing their research efforts on liquid-phase combinatorial synthesis by the use of soluble polymer supports to generate libraries. This macromolecular carrier, in contrast to an insoluble matrix, is soluble in most organic solvents and has a strong tendency for precipitation in particular solvents. Liquid-phase

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!