Journal articles: 'HISCO'

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NAYAK, BIBHUTI B., NADIYA BIHARY NAYAK, RAHUL KUMAR MALLIK, and APARNA MONDAL. "SYNTHESIS AND MAGNETIC PROPERTIES OF COBALT FERRITE WITH DIFFERENT MORPHOLOGIES." International Journal of Modern Physics: Conference Series 22 (January 2013): 164–68. http://dx.doi.org/10.1142/s2010194513010064.

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Different morphologies (spherical, flake and rod) of cobalt ferrite were synthesized using cobalt salt, iron salts, hydrazine hydrate (as a precipitating agent) and CTAB (surfactant) in water as well as ethylene glycol solvents. Four different synthesis ways (HIS, SIH, HISCO and HISG) were adopted to synthesize cobalt ferrite nanopowders using precipitation method. The as-prepared powders obtained after different synthesis ways were calcined at 800°C and structure, microstructure as well as magnetic properties are studied. X-ray diffraction (XRD), scanning electron microscope (SEM) and magnetization studies using pulsed field loop tracer were employed to characterize these cobalt ferrite powders, prepared using different precipitation ways. All the samples are identified with single phase cobalt ferrite and the crystallite size was found to be around 40 nm. Nearly spherical (multifaceted), rod with flake-like, nearly spherical and rod-like morphologies are obtained while synthesizing using HIS, SIH, HISCO and HISG ways, respectively. Rod with flake-like (SIH sample) and rod-like morphologies (HISG sample) show higher coercivity, than the spherical-like (SIH and HISCO smaples) morphology. The highest coericivty was found to be around 925 Oe for HISG sample and highest magnetization is 67 emu/g for HISCO sample.

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Brik, Tymofii. "Social Estates, Occupation, and HISCO: A New Study of Odesa in 1897." East/West: Journal of Ukrainian Studies 9, no. 2 (October 26, 2022): 19–42. http://dx.doi.org/10.21226/ewjus594.

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Odesa was one of the largest and most important cities in the Russian Empire. Numerous studies have addressed the economic development and social structure of Odesa, but there are some gaps in the knowledge of the social stratification during the nineteenth century. Although most studies of the social and economic histories of Ukraine provide qualitative or highly aggregated quantitative data, micro-data at the level of individuals and households in Ukraine are rare. This paper provides new micro-data from the 1897 census in Odesa. It is the first attempt to code occupations of Odesa workers according to the Historical International Standard Classification of Occupations (HISCO). Of the 2,435 individuals in the 457 sampled households analyzed, 1,443 individuals demonstrate 86 of the unique occupations coded with the international HISCO scheme. The analysis compares these HISCO occupations by the social estates, the gender, and the language of the surveyed individuals. The study confirms several old hypotheses but also unearths new findings regarding the number of urban females involved in service and sales occupations.

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Procanin, B. "Barbara Procanin Sales Engineer, Hisco Registration Committee [EIC Volunteer Profile]." IEEE Electrical Insulation Magazine 22, no. 1 (January 2006): 41. http://dx.doi.org/10.1109/mei.2006.1618971.

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DRIBE, MARTIN, and CHRISTER LUNDH. "Partner choice and intergenerational occupational mobility: the case of nineteenth-century rural Sweden." Continuity and Change 24, no. 3 (November 24, 2009): 487–512. http://dx.doi.org/10.1017/s0268416009990178.

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ABSTRACTThis article studies the effects of marriage partner choice on occupational attainment and mobility in five rural parishes in southern Sweden between about 1815 and 1894. It uses an individual-level database containing information on a large number of marriages and the occupational origin of the marrying couple, regardless of whether they were born in the parish or not. Occupations are coded in HISCO and classified using HISCLASS. The results indicate the presence of occupational homogamy in this rural society. The social origin of the partner also mattered a great deal for subsequent occupational attainment and mobility, both upwards and downwards.

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FONSECA, HÉLDER ADEGAR, and PAULO EDUARDO GUIMARÃES. "Social mobility in Portugal (1860–1960): operative issues and trends." Continuity and Change 24, no. 3 (November 24, 2009): 513–46. http://dx.doi.org/10.1017/s026841600999018x.

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ABSTRACTThis article presents the results of a study of social mobility in Portugal from the 1860s to the 1960s. Four distinct social contexts were examined by reference to selected criteria, and marriage records were used as the source for data collection and analysis. The HISCO coding scheme was followed to allow comparisons of intergenerational mobility, stratification, and social change. We present the methodological and operative issues inherent in the hermeneutics of the sources used, identifying difficulties in the process of coding arising from the use of a common language to locate individuals in society. We shall offer an opinion on the pace of Portuguese social mobility during the period.

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Zhao, Jun Xue, Jun Fan, Yuan Ping Chen, and Peng Fei Wang. "Analysis on the Cause of Longitudinal Crack on the Hot-Rolled Ribbed Bar Surface." Advanced Materials Research 295-297 (July 2011): 934–38. http://dx.doi.org/10.4028/www.scientific.net/amr.295-297.934.

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Longitudinal crack on HRB335 hot-rolled ribbed bar surface in cold bending test in HISCO was ever a problem that caused great economic losses. To find the main reason, continuous cast product macro-acid etching test，metallographic examination，scanning electron microscope and EDAX are carried out. It is regarded that the defect is mainly caused by serious subsurface blowholes and internal cracks in the cast product，which can run through the surface in the later hot working process and are oxidized. As a result, the inner surface of these defects can not be welded-on in the rolling process and the cracks happen finally. Related measures are suggested to eliminate the defect.

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Kondo, Naru, Kenichiro Uemura, Naoya Nakagawa, Kenjiro Okada, Shintaro Kuroda, Takeshi Sudo, Naoto Hadano, et al. "A Multicenter, Randomized, Controlled Trial Comparing Reinforced Staplers with Bare Staplers During Distal Pancreatectomy (HiSCO-07 Trial)." Annals of Surgical Oncology 26, no. 5 (February 19, 2019): 1519–27. http://dx.doi.org/10.1245/s10434-019-07222-0.

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Goh, Brian K. P. "A Multicenter, Randomized, Controlled Trial Comparing Reinforced Staplers with Bare Staplers During Distal Pancreatectomy (HiSCO-07 Trial)." Annals of Surgical Oncology 27, S3 (March 27, 2020): 948–49. http://dx.doi.org/10.1245/s10434-020-08401-0.

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Shimomura, Manabu, Satoshi Ikeda, Masahiro Nakahara, Tomohiro Adachi, Yasufumi Saitoh, Yosuke Shimizu, Kazuhiro Toyota, et al. "Prospective cohort study of patients with stage III colorectal cancer aged ≥ 80 years who underwent curative resection: The HiSCO-04 study." Journal of Clinical Oncology 41, no. 4_suppl (February 1, 2023): 102. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.102.

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102 Background: There was no consensus about the safety and effectiveness of adjuvant chemotherapy for patients with stage III colorectal cancer (CRC) aged ≥80 years who underwent curative resection. We conducted a prospective cohort study of patients with stage III CRC aged ≥80 years who underwent curative resection together with a phase II feasibility study on uracil-tegafur and leucovorin (UFT/LV) as adjuvant chemotherapy. Methods: This multi-institutional prospective cohort study involved 17 institutions in Hiroshima, Japan. Patients with stage III CRC aged ≥80 years who underwent curative resection were enrolled. We prospectively collected the clinicopathological data including the status of the administration of adjuvant chemotherapy, follow-up, and oncological outcomes. The primary endpoint was three-year disease-free survival (DFS) and secondary endpoints were three-year overall survival (OS) and relapse-free survival (RFS). Results: From December 2013 to June 2021, 214 patients were examined. There were 99 men and 115 women with the median age of 84 years (range, 80–101). There were stage IIIA diseases in 27 cases, IIIB in 158 cases, and IIIC in 29 cases (TNM eighth edition). Median follow-up time was 42.5 months (range, 0.16–84.04 months). Thirty-six patients died due to CRC and 30 patients died due to other causes. There was recurrence in 58 cases (27.1%), and any treatment was administrated in 29 patients. Secondary cancers were observed in 17 cases in the follow-up period. The three-year DFS was 63.6%, 3-year OS was 76.9%, and 3-year RFS was 63.1%. Adjuvant chemotherapy was administrated in 64 cases and the completion rate was 53%. Adjuvant chemotherapy tends not to be given in older age, poor performance status, high Charlson comorbidity index, and low preoperative prognostic nutritional index. In a study of 80 patients adjusted for background factors using propensity score matching, it was shown that patients who completed planned treatment have improved DFS. Conclusions: Completion of adjuvant chemotherapy may improve prognosis in CRC patients over 80 years of age, but the number of patients who would benefit was limited. Appropriate dose adjustment and supportive care for postoperative adjuvant chemotherapy are important, as well as the need to identify patient groups who will not tolerate chemotherapy.

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Westberg, Annika, Elisabeth Engberg, and Sören Edvinsson. "A Unique Source for Innovative Longitudinal Research: The POPLINK Database." Historical Life Course Studies 3 (March 15, 2016): 20–31. http://dx.doi.org/10.51964/hlcs9351.

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This paper presents the longitudinal database POPLINK, which has been developed at the Demographic Data Base at Umeå University, Sweden. Based on digitized Swedish population registers between c. 1700-1950, the database contains micro-data that covers the agrarian society through industrialization and further on to the Swedish welfare state and contemporary society. It is now possible to study the profound processes of the second demographic transition using individual level data with a proper size population. POPLINK allows for a large array of longitudinal studies, such as social mobility, migration, fertility, mortality, civil status, kinship relations, diseases, disability and causes of death. International standards of occupations (HISCO) and diseases (ICD-10) have been applied, facilitating comparability. POPLINK covers two large regions in Northern Sweden and is built on complete registrations. It is one of the world’s most information-dense historical population databases, covering up to 15 generations and 350,000 individuals described by 300 variables, allowing the ability to monitor populations over time. POPLINK has been built to allow linkage to modern registries, clinical data and medical biobanks, which enables the study of transgenerational effects, heredity and genetic transfers in disease incidence of the population today. DDB serves as an infrastructure for research and is open to researchers of any nationality.

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Takakura, Yuji, Katsunori Shinozaki, Satoshi Ikeda, Hiroyuki Egi, Yuzo Hirata, Manabu Shimomura, Takafumi Oshiro, et al. "Pre- versus postoperative CAPOX plus bevacizumab (CAPOX-Bev) for resectable liver metastases from colorectal cancer (CLM): A randomized phase II/III trial (HiSCO-01)." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): 4021. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.4021.

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4021 Background: The role of neoadjuvant chemotherapy, particularly for those with initially resectable CLM, is controversial. And the optimal regimen and duration to be used in the neoadjuvant setting is not established. We conducted prospective, multicenter, randomized phase II/III study to assess pre-operative 8 cycles of CAPOX-Bev (arm A) plus radical surgery compared with post-operative 8 cycles of CAPOX-Bev (arm B) for patients (pts) with resectable CLM. Methods: The primary endpoint in the Phase II was completion rate of protocol treatment (more than 6 cycles of CAPOX-Bev plus R0 surgical resection) and PFS in the Phase III. The secondary endpoints were OS, ORR (arm A), liver damage (arm A), safety. The Phase III part was terminated due to slow enrollment. Results: 81 pts were enrolled from 10 centers between November 2010 and November 2017. The full analysis set consisted of 76 pts who started protocol treatment (arm A 37 vs. arm B 39). 76 pts had the following characteristics: median age 66 (27-80), median number of liver metastases 2 (1-14), 69.7% male, 67.1% synchronous and 94.7% primary resected. Completion rate of protocol treatment was 89.2% in arm A and 71.8% in arm B (p = .06). ORR was 63.9%, including 2 pts who had pathologically complete response (5.6%). Only 1 pts in arm A could not undergo surgery due to progression of disease. In the chemotherapy safety population, arm B was associated with more grade 3 neutropenia and grade 3 gastrointestinal disorder than arm A. The most frequent surgical adverse event was biliary fistula, with an incidence of 0% in arm A and 10.3% in arm B (p = .02). No patient died from treatment-related adverse events. The median follow-up time was 40 months. The rate of PFS at 3 years was 32.2% in arm A versus 38.5% in arm B (p = .99). Conclusions: Pre-operative 8 cycles of CAPOX-Bev is compatible with radical surgery, but may have no impact on progression-free survival compared with post-operative chemotherapy. Clinical trial information: UMIN000003783 .

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Kaelble, H. "HISCO. Historical International Standard Classification of Occupations. By Marco H. D. van Leeuwen, Ineke Maas and Andrew Miles (Louvain: Leuven University Press, 2002. 441 pp.)." Journal of Social History 38, no. 1 (September 1, 2004): 226. http://dx.doi.org/10.1353/jsh.2004.0091.

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Kondo, Naru, and Yoshiaki Murakami. "Reply to the Letter to the Editor “Re: A Multicenter, Randomized, Controlled Trial Comparing Reinforced Staplers with Bare Staplers During Distal Pancreatectomy (HiSCO-07 Trial)”." Annals of Surgical Oncology 27, S3 (March 27, 2020): 950–51. http://dx.doi.org/10.1245/s10434-020-08406-9.

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Kurayoshi, Manabu, Katsunori Shinozaki, Takao Hinoi, Tsuyoshi Kobayashi, Manabu Shimomura, Masanori Yoshimitsu, Kazuhiro Toyota, et al. "A multi-institutional feasibility study of S-1/oxaliplatin (SOX) plus bevacizumab in patients with advanced/metastatic colorectal cancer: HiSCO-02 prospective phase II study." Journal of Clinical Oncology 33, no. 3_suppl (January 20, 2015): 728. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.728.

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728 Background: mFOLFOX6 regimen, which is a standard regimen for metastatic colorectal cancer (CRC), is inconvenient owing to its requirement for continuous infusion via vascular access. We aimed to investigate the efficacy and safety of S-1/oxaliplatin (SOX) plus bevacizumab, a promising alternative treatment to replace mFOLFOX6. Methods: We undertook a clinical phase II trial in 12 institutions in Hiroshima, Japan. We enrolled individuals aged 20–80 years who had metastatic CRC, had an Eastern Cooperative Oncology Group performance status (PS) of 0 or 1, had assessable lesions, and had received no previous chemotherapy. Eligible patients were assigned SOX plus bevacizumab (S-1: 80-120 mg/body/day, day 1–14 orally administrated, oxaliplatin: 130mg/m2 day 1 i.v., bevacizumab: 7.5mg/kg day 1 i.v. q3w). The primary endpoint was response rate (RR), and the secondary end points were progression-free survival (PFS), overall survival (OS), and safety. Results: From May 2011 to January 2014, 55 patients (mean age, 64 years) were enrolled. The number of metastatic organs were one: 29 cases (52.7%), two or more: 25 cases (45.4%), and 2 cases had no target lesions (3.6%). Median follow up time was 12.8 months (range, 1.4-38.6 months). RR was 45.4% (95% CI, 32.2%-58.6%) and disease control rate was 87.3% (95% CI, 78.5-96.1%). Median PFS and OS time were 9.2 months (95% CI, 7.6-10.8) and 22.0 months (95% CI, 17.7-26.2), respectively. The median number of cycles of chemotherapy was 7 (range, 1-16). The median relative dose intensity of oxaliplatin, S-1, and bevacizumab were 85%, 85%, and 87%, respectively. Major toxic effects (grade 3/4) were thrombocytopenia (5.7%), neutropenia (7.5%), sensory neuropathy (13.2%), and anorexia (17.0%). Conclusions: These data indicated that the SOX plus bevacizumab regimen is effective and well tolerated in patients with metastatic CRC. Clinical trial information: UMIN000004976.

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Yamamoto, Masateru, Tsuyoshi Kobayashi, Akihiko Oshita, Tomoyuki Abe, Toshihiko Kohashi, Takashi Onoe, Saburo Fukuda, et al. "Laparoscopic versus open limited liver resection for hepatocellular carcinoma with liver cirrhosis: a propensity score matching study with the Hiroshima Surgical study group of Clinical Oncology (HiSCO)." Surgical Endoscopy 34, no. 11 (December 11, 2019): 5055–61. http://dx.doi.org/10.1007/s00464-019-07302-y.

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Miguchi, Masashi, Satoshi Ikeda, Manabu Shimomura, Masahiro Nakahara, Tomohiro Adachi, Yasuyo Ishizaki, Yasufumi Saitoh, et al. "Phase 2 multi-institutional prospective feasibility study of uracil-tegafur and leucovorin as adjuvant chemotherapy for patients aged 80 years or more after curative resection of colorectal cancer: The HiSCO-03 study." Journal of Clinical Oncology 41, no. 4_suppl (February 1, 2023): 101. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.101.

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101 Background: There is no consensus on the safety and effectiveness of adjuvant chemotherapy for patients with stage III colorectal cancer (CRC) aged ≥80 years who underwent curative resection. We conducted a prospective phase II feasibility study of uracil-tegafur and leucovorin (UFT/LV) as adjuvant chemotherapy in this population. Methods: This study involved 15 institutions of the Hiroshima Surgical Oncology Study Group (HiSCO). Patients with stage III CRC aged ≥80 years who underwent curative resection with an Eastern Cooperative Oncology Group performance status of 0–1 were enrolled. Eligible patients received UFT/LV therapy (UFT, 300 mg/m2 per day as tegafur; LV, 75 mg/day on days 1–28, every 35 days for five courses). Primary endpoint was feasibility, and secondary endpoints were safety and relative dose intensity. Results: Sixty-nine patients were enrolled in the study between December 2013 and June 2021. Of the 69 patients, 65 were included in the analysis, excluding two ineligible patients and two who discontinued before treatment commenced. There were 32 males and 33 females with a median age of 82 years (range, 80–88 years). There were four patients with stage IIIA CRC, 49 with stage IIIB, and 12 with stage IIIC. In the primary endpoint, administration completion rate was 67.3% (95% confidence interval: 54.9The median relative dose intensities were 84% (range, 4–100%) for UFT, and 100% (range, 4–100%) for LV. Incidence of grade three or higher adverse events were neutropenia (1.5%), aspartate transaminase elevation (3%), alanine transaminase elevation (1.5%), oral mucositis (3%), anemia (1.5%), and diarrhea (4.6%). No treatment-related deaths occurred. An independent risk factor was not identified in the background risk factor analysis for treatment discontinuation. Conclusions: Uracil-tegafur and leucovorin are not recommended as standard adjuvant therapy for patients with stage III CRC ≥80 years of age because of the possibility of lower completion rates. The frequency of serious adverse events was acceptable, and safety was confirmed in the treated patients. It is necessary to clarify the background of patients in which administration is discontinued and to investigate the impact on long-term prognosis. Clinical trial information: R000013902 .

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Jijón-Moreno, Saúl, Cynthia Marcos-Jiménez, Raúl O. Pedraza, Alberto Ramírez-Mata, I. García de Salamone, Ana Fernández-Scavino, Claudia A. Vásquez-Hernández, Lucia Soto-Urzúa, and Beatriz E. Baca. "The ipdC, hisC1 and hisC2 genes involved in indole-3-acetic production used as alternative phylogenetic markers in Azospirillum brasilense." Antonie van Leeuwenhoek 107, no. 6 (April 5, 2015): 1501–17. http://dx.doi.org/10.1007/s10482-015-0444-0.

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Nagahara, Takashi. "Hisao Tominaga." Results in Mathematics 28, no. 1-2 (August 1995): 5–11. http://dx.doi.org/10.1007/bf03322234.

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Gangoli, Varun Shenoy, M. Anto Godwin, Gadhadar Reddy, Robert Kelley Bradley, and Andrew R. Barron. "The State of HiPco Single-Walled Carbon Nanotubes in 2019." C — Journal of Carbon Research 5, no. 4 (October 28, 2019): 65. http://dx.doi.org/10.3390/c5040065.

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High-pressure carbon monoxide (HiPco)-synthesized single-walled carbon nanotubes (SWCNTs) have been a widely studied carbon nanomaterial for nearly two decades. It has been the de facto standard for SWCNT research, be it functionalization, separation and purification, or composites, as a result of the consistent, high-quality material that was made available at an affordable price to researchers worldwide. The recent shutdown of the HiPco reactor at Rice University has resulted in a scarcity of HiPco material available to the research community, and a new source of similar SWCNTs is desperately needed. Continued research and development on the design, materials used, and the overall process have led to a new HiPco material, referred to as NoPo HiPCO®, as an alternative to the erstwhile Rice HiPco SWCNTs. In this work, we have compared the two HiPco materials, and aim to provide more clarity for researchers globally on the state of HiPco SWCNTs for research and applications alike in 2019.

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Bergstrand, Hilding. "Histo-pathological examination." Acta Medica Scandinavica 77, no. 5-6 (April 24, 2009): 492–501. http://dx.doi.org/10.1111/j.0954-6820.1932.tb15411.x.

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Li, Huaping. "Electronically Pure Single Chirality Semiconducting Single-Walled Carbon Nanotube for Large Scale Electronic Devices." MRS Advances 2, no. 02 (2017): 83–88. http://dx.doi.org/10.1557/adv.2017.15.

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Abstract Carbon nanotube thin film transistors (TFTs) with characteristics resembling those of TFTs constructed on amorphous silicon, low-temperature polycrystalline silicon and metal oxides were fabricated on (6,5) single chirality single-walled carbon nanotube (SWCNT) thin film deposited from electronically pure semiconducting (6,5) single chirality single-walled carbon nanotube (SWCNT) ink. This ink was extracted in industrial scale from raw SWCNTs produced using high pressure carbon monoxide conversion, and deposited on pretreated substrates to form uniform and consistent (6,5) HiPCO SWCNT thin film using solution process. The (6,5) HiPCO SWCNT thin films were characterized as pure semiconductor without metallic impurities showing classic nonlinear current-bias curves in Schottky-type diodes. Both N-type and P-type (6,5) HiPCO SWCNT TFTs were fabricated with femto Ampere off-current and ION/IOFF ratio of 108 by depositing SiNx and HfO2 dielectrics on the top of (6,5) HiPCO SWCNT thin films, respectively. The (6,5) HiPCO SWCNT inverter with voltage gain of 52 was also demonstrated by wire-bonding one P-type HiPCO SWCNT TFT to one N-type HiPCO SWCNT TFT.

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Kammula, Udai S., Ronald Ghossein, Satyajit Bhattacharya, and Daniel G. Coit. "Serial Follow-Up and the Prognostic Significance of Reverse Transcriptase-Polymerase Chain Reaction—Staged Sentinel Lymph Nodes From Melanoma Patients." Journal of Clinical Oncology 22, no. 19 (October 1, 2004): 3989–96. http://dx.doi.org/10.1200/jco.2004.03.052.

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Purpose Reverse transcriptase-polymerase chain reaction (RT-PCR) may provide an extremely sensitive method for detection of occult nodal disease. We evaluated the role of a single-marker RT-PCR assay for tyrosinase mRNA in the detection of melanoma sentinel lymph node (SLN) metastases and correlated the results with long-term clinical outcome. Patients and Methods One hundred twelve patients who underwent SLN biopsy for melanoma were prospectively analyzed. SLNs were bivalved, with half of each specimen evaluated by histologic methods and the other half evaluated by nested RT-PCR for tyrosinase. Results Fifteen patients (13%) had histologically positive SLNs, all of whom were also positive by RT-PCR (HISTO+/PCR+). Thirty-nine patients (35%) had SLNs that were negative by both histology and RT-PCR (HISTO−/PCR−). Fifty-eight patients (52%) were histologically negative but upstaged with a positive RT-PCR result (HISTO−/PCR+). Initially, at a median follow-up of 42 months, recurrence rates among the three cohorts were statistically different (HISTO+/PCR+, 53%; HISTO−/PCR+, 14%; and HISTO−/PCR−, 0%). However, at a longer median follow-up (67 months), recurrence rates for the HISTO−/PCR+ (24%) and HISTO−/PCR− (15%) groups were no longer statistically different (P = .25). The median time to relapse between the HISTO−/PCR+ and HISTO−/PCR− groups differed by 10 months (31 v 41 months, respectively). Conclusion With extended follow-up of patients with histologically negative SLNs, detection of submicroscopic disease by tyrosinase RT-PCR does not define a subgroup that is at higher recurrence risk when compared with patients with RT-PCR–negative SLNs. Future studies evaluating molecular staging will require approximately 5 years of median follow-up to accurately define outcome for patients with occult melanoma metastases.

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Choi, Sungkyoung, Sungyoung Lee, Yongkang Kim, Heungsun Hwang, and Taesung Park. "HisCoM-GGI: Hierarchical structural component analysis of gene–gene interactions." Journal of Bioinformatics and Computational Biology 16, no. 06 (December 2018): 1840026. http://dx.doi.org/10.1142/s0219720018400267.

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Although genome-wide association studies (GWAS) have successfully identified thousands of single nucleotide polymorphisms (SNPs) associated with common diseases, these observations are limited for fully explaining “missing heritability”. Determining gene–gene interactions (GGI) are one possible avenue for addressing the missing heritability problem. While many statistical approaches have been proposed to detect GGI, most of these focus primarily on SNP-to-SNP interactions. While there are many advantages of gene-based GGI analyses, such as reducing the burden of multiple-testing correction, and increasing power by aggregating multiple causal signals across SNPs in specific genes, only a few methods are available. In this study, we proposed a new statistical approach for gene-based GGI analysis, “Hierarchical structural CoMponent analysis of Gene–Gene Interactions” (HisCoM-GGI). HisCoM-GGI is based on generalized structured component analysis, and can consider hierarchical structural relationships between genes and SNPs. For a pair of genes, HisCoM-GGI first effectively summarizes all possible pairwise SNP–SNP interactions into a latent variable, from which it then performs GGI analysis. HisCoM-GGI can evaluate both gene-level and SNP-level interactions. Through simulation studies, HisCoM-GGI demonstrated higher statistical power than existing gene-based GGI methods, in analyzing a GWAS of a Korean population for identifying GGI associated with body mass index. Resultantly, HisCoM-GGI successfully identified 14 potential GGI, two of which, (NCOR2 [Formula: see text] SPOCK1) and (LINGO2 [Formula: see text] ZNF385D) were successfully replicated in independent datasets. We conclude that HisCoM-GGI method may be a valuable tool for genome to identify GGI in missing heritability, allowing us to better understand the biological genetic mechanisms of complex traits. We conclude that HisCoM-GGI method may be a valuable tool for genome to identify GGI in missing heritability, allowing us to better understand biological genetic mechanisms of complex traits. An implementation of HisCoM-GGI can be downloaded from the website ( http://statgen.snu.ac.kr/software/hiscom-ggi ).

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Walsh, Kevin J., Stavan Shah, Ping Wei, Samuel Oberdick, Dana McTigue, and Gunjan Agarwal. "A Comparison of Histo-Chemical and Histo-Magnetic Detection of Iron." Biophysical Journal 118, no. 3 (February 2020): 462a. http://dx.doi.org/10.1016/j.bpj.2019.11.2571.

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Mok, Kim, Lee, Choi, Lee, Jang, and Park. "HisCoM-PAGE: Hierarchical Structural Component Models for Pathway Analysis of Gene Expression Data." Genes 10, no. 11 (November 14, 2019): 931. http://dx.doi.org/10.3390/genes10110931.

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Although there have been several analyses for identifying cancer-associated pathways, based on gene expression data, most of these are based on single pathway analyses, and thus do not consider correlations between pathways. In this paper, we propose a hierarchical structural component model for pathway analysis of gene expression data (HisCoM-PAGE), which accounts for the hierarchical structure of genes and pathways, as well as the correlations among pathways. Specifically, HisCoM-PAGE focuses on the survival phenotype and identifies its associated pathways. Moreover, its application to real biological data analysis of pancreatic cancer data demonstrated that HisCoM-PAGE could successfully identify pathways associated with pancreatic cancer prognosis. Simulation studies comparing the performance of HisCoM-PAGE with other competing methods such as Gene Set Enrichment Analysis (GSEA), Global Test, and Wald-type Test showed HisCoM-PAGE to have the highest power to detect causal pathways in most simulation scenarios.

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Hügle, Thomas, and Veit Krenn. "Histo-Pathophysiologie der Gichtarthritis." Therapeutische Umschau 73, no. 3 (March 2016): 137–40. http://dx.doi.org/10.1024/0040-5930/a000769.

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Zusammenfassung. Gicht ist eine häufige Ursache von entzündlichen Arthritiden und deformierenden Knochenerosionen. Die zugrundeliegende zelluläre und subzelluläre Entzündungsreaktion ist leider nur teilweise verstanden. Das Inflammasom als intrazellulärer Sensor von Uratkristallen führt zur Freisetzung von Interleukin (IL)-1. Histologisch führt die Anreicherung von Uratkristallen in der Synovialmembran zu deren Hyperplasie und zu einer Fibrinablagerung. In einem zweiten Schritt wandern neutrophile Leukozyten ein und es kommt zur Lymphozytenproliferation. Neutrophile Leukozyten induzieren NETs, welche wiederum entzündliche Zytokine degradieren können. Im Verlauf kommt es zudem zur vermehrten Expression von Tumor Nekrose Faktor (TNF)-Rezeptoren, welche als natürliche TNF-Hemmer wirken. Auch eine vermehrte IL-10 Expression ist beim Abklingen der Entzündung beteiligt. Bei der chronischen Gicht werden Tophi von Histiozyten und Riesenzellen umrandet. Herum bildet sich durch Fibrozyten eine fibrotische Reaktion mit vermehrter extrazellulärer Matrix. Auch hier kommt es zur Lymphozytenproliferation, wahrscheinlich einer Th-2 Polarisation welche die Fibrose weiter fördert. Lymphozyten sind durch die Bildung von RANK-Ligand auch an der Stimulierung von Osteoklasten und damit Knochenerosionen beteiligt. Zusammenfassend kann das Verständnis der Entzündungsreaktion bei der Gichtarthritis dabei helfen, neue therapeutische Ansätze zu entwickeln.

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Thomas, Meeta, and Sharmila Annadurai. "Histo-Morphological Study of Soft Tissue Tumors." Indian Journal of Pathology: Research and Practice 8, no. 5 (2019): 614–19. http://dx.doi.org/10.21088/ijprp.2278.148x.8519.15.

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An, Jingna, Qixia Chen, Qianqian Liu, Chenli Rao, Dongdong Li, Tingting Wang, Chuanmin Tao, and Lanlan Wang. "Evaluation of the HISCL Anti-Treponema pallidum Assay as a Screening Test for Syphilis." Clinical and Vaccine Immunology 22, no. 7 (May 13, 2015): 817–22. http://dx.doi.org/10.1128/cvi.00116-15.

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ABSTRACTThe resurgence of syphilis in recent years has become a serious threat to public health worldwide, and the serological detection of specific antibodies againstTreponema pallidumremains the most reliable method for laboratory diagnosis of syphilis. This study examined the performance of the recently launched HISCL anti-Treponema pallidum(anti-TP) assay as a screening test for syphilis in a high-volume laboratory. The HISCL anti-TP assay was tested in 300 preselected syphilis-positive samples, 704 fresh syphilis-negative samples, 48 preselected potentially interfering samples, and 30 “borderline” samples and was compared head to head with the commercially available Lumipulse G TP-N. In this study, the HISCL anti-TP assay was in perfect agreement with the applied testing algorithms with an overall agreement of 100%, comparable to that of Lumipulse G TP-N (99.63%). The sensitivity and specificity of the HISCL anti-TP assay were 100% (95% confidence interval [CI], 98.42% to 100%) and 100% (95% CI, 99.37% to 100%), respectively. Considering the excellent ease of use and automation, high throughput, and its favorable sensitivity and specificity, the HISCL anti-TP assay may represent a new choice for syphilis screening in high-volume laboratories.

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Albritton, W. L., and L. Chui. "Sequence analysis of two deletion mutants in the hisC gene of Salmonella typhimurium." Canadian Journal of Microbiology 40, no. 2 (February 1, 1994): 158–60. http://dx.doi.org/10.1139/m94-027.

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Limited sequencing of the terminal region of the hisC gene in two deletion mutants involving the hisC gene of Salmonella typhimurium was carried out after polymerase chain reaction amplification of the appropriate region, using oligonucleotide primers selected from the published sequence of the histidine operon from this organism. his2648 was shown to have a 34 base pair deletion in the terminal region of the hisC gene between the P2 promoter and the Shine–Delgamo sequence of the hisB gene. hisHB22 was shown to have a 1.4 kilobase deletion extending from the TGA termination codon of the hisC gene to the middle of the hisH gene. The sequence data were consistent with previous genetic and phenotypic characterization of these strains.Key words: Salmonella typhimurium, hisC gene, deletion mutants.

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Zhang, Yang, Chaoyue Chen, Yangfan Cheng, Danni Cheng, Fumin Zhao, and Jianguo Xu. "MRI-Based Texture Features as Potential Prognostic Biomarkers in Anaplastic Astrocytoma Patients Undergoing Surgical Treatment." Contrast Media & Molecular Imaging 2020 (June 12, 2020): 1–7. http://dx.doi.org/10.1155/2020/2126768.

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Objectives. The purpose of this study was to investigate whether texture features from magnetic resonance imaging (MRI) were associated with the overall survival (OS) of anaplastic astrocytoma (AA) patients undergoing surgical treatment. Methods. A total of 51 qualified patients who were diagnosed with AA and underwent surgical interventions in our institution were enrolled in this retrospective study. Patients were followed up for at least 30 months or until death. Texture features derived from histogram-based matrix (HISTO) and grey-level co-occurrence matrix (GLCM) were extracted from preoperative contrast-enhanced T1-weighted images. Each texture feature was dichotomized based on its optimal cutoff value calculated by receiver operating characteristics curve analysis. Kaplan–Meier analysis and log rank test were conducted to compare the 30-month OS between the dichotomized subgroups. Multivariate Cox regression analysis was performed to determine independent prognostic factors. Results. Three HISTO-derived features (HISTO-Energy, HISTO-Entropy, and HISTO-Skewness) and five GLCM-derived features (GLCM-Contrast, GLCM-Energy, GLCM-Entropy, GLCM-Homogeneity, and GLCM-Dissimilarity) were found to be significantly correlated with 30-month OS. Moreover, GLCM-Homogeneity (p=0.001, hazard ratio = 6.351) was suggested to be the independent predictor of the patient survival. Conclusion. MRI-based texture features have the potential to be applied as prognostic biomarkers in AA patients undergoing surgical treatment.

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Estrela, Vania V. "DICOM’s Standardization in Histo-Pathology." Medical Technologies Journal 4, no. 3 (December 7, 2020): 578–79. http://dx.doi.org/10.26415/2572-004x-vol4iss3p578-579.

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Background: The Digital Imaging and Communications in Medicine (DICOM) standard helps to represent, store, and to exchange healthcare images associated with its data. DICOM develops over time and is continuously adapted to match the rigors of new clinical demands and technologies. An uphill battle in this regard is to conciliate new software programs with legacy systems. Methods: This work discusses the essential aspects of the standard and assesses its capabilities and limitations in a multisite, multivendor healthcare system aiming at Whole Slicing Image (WSI) procedures. Selected relevant DICOM attributes help to develop and organize WSI applications that extract and handle image data, integrated patient records, and metadata. DICOM must also interface with proprietary file formats, clinical metadata and from different laboratory information systems. Standard DICOM validation tools to measure encoding, storing, querying and retrieval of medical data can verify the generated DICOM files over the web. Results: This work investigates the current regulations and recommendations for the use of DICOM with WSI data. They rely mostly on the EU guidelines that help envision future needs and extensions based on new examination modalities like concurrent use of WSI with in-vitro imaging and 3D WSI. Conclusion: A DICOM file format and communication protocol for pathology has been defined. However, adoption by vendors and in the field is pending. DICOM allows efficient access and prompt availability of WSI data as well as associated metadata. By leveraging a wealth of existing infrastructure solutions, the use of DICOM facilitates enterprise integration and data exchange for digital pathology. In the future, the DICOM standard will have to address several issues due to the way samples are gathered and encompassing new imaging technologies.

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Fukui, Norihiko. "Sur l’œuvre de Hisao Otsuka." Actuel Marx 2, no. 2 (1987): 85. http://dx.doi.org/10.3917/amx.002.0085.

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Yoo, Yoon Jae. "Reconceptualization of Histo-Genetic Principle." Journal for History of Mathematics 26, no. 5_6 (November 30, 2013): 389–400. http://dx.doi.org/10.14477/jhm.2013.26.5_6.389.

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Haot, J., A. Jouret, and P. Mainguet. "Histo-endoscopic confrontations in 1988." Acta Endoscopica 18, S2 (March 1988): 21. http://dx.doi.org/10.1007/bf02980939.

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Watanabe, Hitoshi. "Professor Hisao Aruga (1910–1991)." Journal of Invertebrate Pathology 58, no. 2 (September 1991): 294–96. http://dx.doi.org/10.1016/0022-2011(91)90079-6.

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Usmani, Fareya, Imran Munir, Ghazanfar Saleem Jadoon, and Nadia Shams. "Hadfield’s procedure for Duct Ectasia; The histopathological spectrum." Professional Medical Journal 27, no. 01 (January 10, 2020): 29–34. http://dx.doi.org/10.29309/tpmj/2019.27.01.3062.

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Objectives: Mammary duct ectasia, a benign condition of breast is a diagnostic challenge both for surgeon and histo-pathologist. Duct ectasia is commonly encountered in clinical practice and its histo-pathological spectrum needs to be studied in detail in our patients. Study Design: Descriptive cross sectional study. Setting: Sir Syed College of Medical Sciences Karachi after ethical approval. Period: 24 months from June 2016-June 2018. Material & Methods: Total 104 female patients (>18 years) were included after informed consent. Patients presenting with lump in breast, breast pain, tenderness or nipple discharge were screened by ultrasound breasts or mammography. Pregnant women, patients having high grade fever, hematological abnormalities, coagulopathy, axillary lymphadenopathy, papilloma of nipple, galactocele, lactating mothers and those with past history of malignancy were excluded. Only those cases were included that had diagnosis of duct ectasia on ultrasound breast. Cone excision (Hadfield’s operation) was performed after pre-requisites and histo-pathological findings were documented. Patients were kept admitted under observation for minimum 24 hours and then followed up with histo-pathology report. Results: Amongst 104 cases, mean age was 41+6.35(range=30-50) years. The mean duration of symptoms was11.6+5.76 (range=1-24) months. 72(69%) women were married and 32(30.8%) were unmarried. As per histo-pathology report duct ectasia was found in 102(98%), hyperplasia in 61(58.7%), metaplasia in 41(39.4%) and atypical cells in 2(1.9%) samples. Conclusions: Current study demonstrated final outcome of metaplasia in thirty nine percent cases with initial clinical and sonographic diagnosis of duct ectasia. This suggests the triple technique evaluation (i.e. clinical assessment, ultrasound breast/mammography along with histo-pathological assessment) to identify cases with metaplasia. The high risk cases should be frequently followed with clinical assessment and imaging along with BRCA 1 & 2 gene for timely detection and intervention of breast malignancy.

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Wang, Lijun, and Shusuke Oura. "Evaluation of the Antioxidant Potential of Tea by Optical Absorption Spectroscopy in the Presence of Double-Stranded DNA-Encased Single-Walled Carbon Nanotubes." Journal of Nanoelectronics and Optoelectronics 16, no. 1 (January 1, 2021): 31–37. http://dx.doi.org/10.1166/jno.2021.2868.

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Developing a simple method to qualitatively and quantitatively assess food quality is essential. Available methods primarily rely on nanotechnology and offer high selectivity and sensitivity. In this study, we aimed to develop a sensitive nano-probe, and to this end, a double-stranded DNA-encased HiPco carbon nanotube (dsDNA-HiPco) hybrid was prepared and used to evaluate the antioxidant potential of Chinese tea against H2O2, using a range of irradiation wavelengths. The morphology and dispersion of dsDNA-HiPco hybrids were analysed using atomic force microscopy, which showed a homogeneous dispersion of the rod-shaped tubes. The antioxidant effect of the hybrid was evaluated by near-infrared absorption and photoluminescence. The experimental results revealed that the tea exerted excellent antioxidant effects when the dsDNA-HiPco hybrid was pre-treated with 0.03 wt.% H2O2. Catechin contained in the Chinese tea played a pivotal role in exerting the antioxidant effect. Therefore, the simple detection method proposed herein can be successfully applied in various fields, including biology, medicine, and the food industry.

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Oh, Jonghwa, Evan L. Floyd, Mahesh Parit, Virginia A. Davis, and Claudiu T. Lungu. "Heat Treatment of Buckypaper for Use in Volatile Organic Compounds Sampling." Journal of Nanomaterials 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/3248059.

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Three types of buckypapers (BPs), two of them fabricated with arc discharge (AD) single-walled carbon nanotubes (SWNTs) (acetone-cleaned AD BP and methanol-cleaned AD BP) and one with high-pressure carbon monoxide (HiPco) SWNTs (HiPco BP), were heat-treated at different conditions to find the specific conditions for each type that improve the adsorption properties. Based on thermogravimetric analysis (TGA) data, three heat treatment conditions were designed for the AD BPs and another three conditions for the HiPco BPs. Also, changes in weight and physical integrity before and after the heat treatment were considered. Heating at 300°C for 90 minutes was selected for acetone-cleaned AD BP, in which the BP kept its physical integrity and yielded a relatively high Brunauer, Emmett, and Teller (BET) surface area (970 ± 18 m2/g), while methanol-cleaned AD BP was excluded because of its physical change. For HiPco BP, a condition of 300°C heating for 30 minutes was chosen as a relatively higher surface area (933 ± 54 m2/g) and less weight loss (5%) were observed.

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Attallah, Omneya, Fatma Anwar, Nagia M. Ghanem, and Mohamed A. Ismail. "Histo-CADx: duo cascaded fusion stages for breast cancer diagnosis from histopathological images." PeerJ Computer Science 7 (April 27, 2021): e493. http://dx.doi.org/10.7717/peerj-cs.493.

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Breast cancer (BC) is one of the most common types of cancer that affects females worldwide. It may lead to irreversible complications and even death due to late diagnosis and treatment. The pathological analysis is considered the gold standard for BC detection, but it is a challenging task. Automatic diagnosis of BC could reduce death rates, by creating a computer aided diagnosis (CADx) system capable of accurately identifying BC at an early stage and decreasing the time consumed by pathologists during examinations. This paper proposes a novel CADx system named Histo-CADx for the automatic diagnosis of BC. Most related studies were based on individual deep learning methods. Also, studies did not examine the influence of fusing features from multiple CNNs and handcrafted features. In addition, related studies did not investigate the best combination of fused features that influence the performance of the CADx. Therefore, Histo-CADx is based on two stages of fusion. The first fusion stage involves the investigation of the impact of fusing several deep learning (DL) techniques with handcrafted feature extraction methods using the auto-encoder DL method. This stage also examines and searches for a suitable set of fused features that could improve the performance of Histo-CADx. The second fusion stage constructs a multiple classifier system (MCS) for fusing outputs from three classifiers, to further improve the accuracy of the proposed Histo-CADx. The performance of Histo-CADx is evaluated using two public datasets; specifically, the BreakHis and the ICIAR 2018 datasets. The results from the analysis of both datasets verified that the two fusion stages of Histo-CADx successfully improved the accuracy of the CADx compared to CADx constructed with individual features. Furthermore, using the auto-encoder for the fusion process has reduced the computation cost of the system. Moreover, the results after the two fusion stages confirmed that Histo-CADx is reliable and has the capacity of classifying BC more accurately compared to other latest studies. Consequently, it can be used by pathologists to help them in the accurate diagnosis of BC. In addition, it can decrease the time and effort needed by medical experts during the examination.

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Krishnan, Gayathri, Margaret Power, J. Ryan Bariola, and Ryan K. Dare. "271. Fungal Diagnostic Studies in Histoplasmosis." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S150. http://dx.doi.org/10.1093/ofid/ofz360.346.

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Abstract Background Histoplasmosis (histo) is a common cause of invasive fungal infection in endemic regions and accurate diagnosis is difficult without direct tissue culture or pathology. Indirect fungal antigen testing for various fungal pathogens is typically performed to assist with diagnostic workup though cross-reaction can lead to difficulty interpreting results. We aimed to evaluate the prevalence of positive antigen testing for non-Histoplasma fungal pathogens in patients with proven invasive histo. Methods We performed a retrospective review of adult patients with proven invasive histo from 2010–2018 at our institution. For inclusion purposes, histo was confirmed by either fungal culture and/or cytology. Patient demographics, clinical characteristics and results of fungal antigen testing for Histoplasma, Blastomyces, Aspergillus, Cryptococcus and β-d-glucan were evaluated. Two different urine Histoplasma antigen assays were used during the study period. Results 57 (31%) of 182 patients diagnosed with histo during the study period had culture or cytology evidence of disease and were included in all further analysis. Thirty-two (56%) of these patients were male, 35 (61.4%) were Caucasian and the mean age was 50.1 years. HIV (20; 35%) and being on immunosuppressive medications (21, 37%) were common in this population. The majority of cases were classified as disseminated histo (40, 70%) followed by acute pulmonary (10; 18%) and chronic pulmonary (7, 12%) disease. Results of fungal antigen testing are documented in the table. Chi-squared analysis was performed. Conclusion There is a frequent cross reaction of non-Histoplasma fungal tests in patients with histo. In our review, there was a high rate of cross reaction with Blastomyces antigen, which can be confusing in regions where both pathogens coexist. Elevation of β-d-glucan was high in these patients. Urine Histoplasma antigen sensitivity was higher with MiraVista testing for disseminated disease in our review. While noninvasive fungal tests are helpful in diagnosis of these infrequent infections, clinicians must still maintain knowledge of the clinical differences between these fungal pathogens and be aware of the limitations of these tests. A prospective study is needed to better define differences between individual Histoplasma tests. Disclosures All authors: No reported disclosures.

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Bassani, C., C. Manzo, F. Braga, M. Bresciani, C. Giardino, and L. Alberotanza. "The impact of the microphysical properties of aerosol on the atmospheric correction of hyperspectral data in coastal waters." Atmospheric Measurement Techniques 8, no. 3 (March 27, 2015): 1593–604. http://dx.doi.org/10.5194/amt-8-1593-2015.

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Abstract. Hyperspectral imaging provides quantitative remote sensing of ocean colour by the high spectral resolution of the water features. The HICO™ (Hyperspectral Imager for the Coastal Ocean) is suitable for coastal studies and monitoring. The accurate retrieval of hyperspectral water-leaving reflectance from HICO™ data is still a challenge. The aim of this work is to retrieve the water-leaving reflectance from HICO™ data with a physically based algorithm, using the local microphysical properties of the aerosol in order to overcome the limitations of the standard aerosol types commonly used in atmospheric correction processing. The water-leaving reflectance was obtained using the HICO@CRI (HICO ATmospherically Corrected Reflectance Imagery) atmospheric correction algorithm by adapting the vector version of the Second Simulation of a Satellite Signal in the Solar Spectrum (6SV) radiative transfer code. The HICO@CRI algorithm was applied on to six HICO™ images acquired in the northern Mediterranean basin, using the microphysical properties measured by the Acqua Alta Oceanographic Tower (AAOT) AERONET site. The HICO@CRI results obtained with AERONET products were validated with in situ measurements showing an accuracy expressed by r2 = 0.98. Additional runs of HICO@CRI on the six images were performed using maritime, continental and urban standard aerosol types to perform the accuracy assessment when standard aerosol types implemented in 6SV are used. The results highlight that the microphysical properties of the aerosol improve the accuracy of the atmospheric correction compared to standard aerosol types. The normalized root mean square (NRMSE) and the similar spectral value (SSV) of the water-leaving reflectance show reduced accuracy in atmospheric correction results when there is an increase in aerosol loading. This is mainly when the standard aerosol type used is characterized with different optical properties compared to the local aerosol. The results suggest that if a water quality analysis is needed the microphysical properties of the aerosol need to be taken into consideration in the atmospheric correction of hyperspectral data over coastal environments, because aerosols influence the accuracy of the retrieved water-leaving reflectance.

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Bassani, C., C. Manzo, F. Braga, M. Bresciani, C. Giardino, and L. Alberotanza. "Impact of the aerosol type on HICO™ atmospheric correction in coastal waters." Atmospheric Measurement Techniques Discussions 7, no. 5 (May 23, 2014): 5147–72. http://dx.doi.org/10.5194/amtd-7-5147-2014.

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Abstract. The aim of this work is to evaluate the radiative impact of the aerosol type on the results of the atmospheric correction of HICO™ (Hyperspectral Imager for the Coastal Ocean) hyperspectral data. The reflectance was obtained by using the HICO@CRI (HICO ATmospherically Corrected Reflectance Imagery) algorithm, a physically-based atmospheric correction algorithm developed specifically for HICO™ data by adapting the vector version of the Second Simulation of a Satellite Signal in the Solar Spectrum (6SV) radiative transfer code. The HICO@CRI algorithm was applied on six HICO™ images acquired in the Northern part of the Mediterranean Basin, using the micro-physical properties measured with a CIMEL sun sky-radiometer at the Acqua Alta Oceanographic Tower (AAOT) AERONET site and the optical properties of the maritime, continental, and urban aerosol types provided by default by the 6SV. The results highlight that the aerosol type can improve the accuracy of the atmospheric correction. Indeed, the accuracy of the water reflectance retrieved from the available HICO™ data decreases in the sensor spectral domain, considering the AERONET micro-physical properties, of 30% using the urban aerosol type, of 20% using the continental type, and finally of less than 10% assuming a maritime type. Thus, the aerosol type has to be taken into consideration in the atmospheric correction of hyperspectral data over coastal environment, if water quality analysis has to be performed, because of the influence of aerosol type on the water reflectance.

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Feng, Shu, Bin Wei, Qianqian Liu, Tingting Wang, Dongdong Li, Chenli Rao, Chuanmin Tao, and Lanlan Wang. "Evaluation of the Novel HISCL Chemiluminescence Enzyme Immunoassay for Laboratory Screening of Hepatitis C Virus." Clinical and Vaccine Immunology 23, no. 7 (May 11, 2016): 652–54. http://dx.doi.org/10.1128/cvi.00078-16.

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The hepatitis C virus (HCV) antibody assay remains the first-line screening test to identify HCV infection. The newly arrived HISCL Anti-HCV assay had a satisfactory seroconversion sensitivity. Its sensitivity and specificity were 98.97 and 100% for clinical samples. In general, the HISCL Anti-HCV assay may be a novel choice for clinical HCV screening.

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Cano, David A., Chakib Mouslim, Juan A. Ayala, Francisco García-del Portillo, and Josep Casadesús. "Cell Division Inhibition in Salmonella typhimuriumHistidine-Constitutive Strains: an ftsI-Like Defect in the Presence of Wild-Type Penicillin-Binding Protein 3 Levels." Journal of Bacteriology 180, no. 19 (October 1, 1998): 5231–34. http://dx.doi.org/10.1128/jb.180.19.5231-5234.1998.

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ABSTRACT Histidine-constitutive (Hisc) strains ofSalmonella typhimurium undergo cell division inhibition in the presence of high concentrations of a metabolizable carbon source. Filaments formed by Hisc strains show constrictions and contain evenly spaced nucleoids, suggesting a defect in septum formation. Inhibitors of penicillin-binding protein 3 (PBP3) induce a filamentation pattern identical to that of Hisc strains. However, the Hisc septation defect is caused neither by reduced PBP3 synthesis nor by reduced PBP3 activity. Gross modifications of peptidoglycan composition are also ruled out.d-Cycloserine, an inhibitor of the soluble pathway producing peptidoglycan precursors, causes phenotypic suppression of filamentation, suggesting that the septation defect of Hiscstrains may be caused by scarcity of PBP3 substrate.

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Harrington, Patrick R., Jan Vinjé, Christine L. Moe, and Ralph S. Baric. "Norovirus Capture with Histo-Blood Group Antigens Reveals Novel Virus-Ligand Interactions." Journal of Virology 78, no. 6 (March 15, 2004): 3035–45. http://dx.doi.org/10.1128/jvi.78.6.3035-3045.2004.

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ABSTRACT Noroviruses are genetically diverse, uncultivable, positive-sense RNA viruses and are the most common cause of epidemic acute gastroenteritis in humans in the United States. Recent studies of norovirus attachment in vitro by using recombinant virus-like particles (VLPs) suggest that various norovirus strains exhibit different patterns of attachment to ABH histo-blood group antigens, which are carbohydrate epitopes present in high concentrations on mucosal cell surfaces of the gut. However, attachment of live norovirus strains to histo-blood group antigens has not been investigated to date. Utilizing a newly designed magnetic bead-virus capture method, we characterized histo-blood group antigen attachment properties of various norovirus strains obtained from clinical stool specimens to compare the attachment properties of wild-type virus and VLPs and to further map norovirus attachment. Consistent with previous reports using VLPs, various strains of noroviruses exhibited different patterns of attachment to histo- blood group antigens. Norwalk virus bound specifically to H type 1, H type 3, and Leb. Two genogroup II noroviruses, one representing the Toronto genotype and the other from a novel genotype, bound specifically to Leb. A Desert Shield-like strain did not attach to H types 1, 2, or 3, H type 1 and 3 precursors, Lea, or Leb. Surprisingly, wild-type Snow Mountain virus (SMV) attached specifically to H type 3, which contradicted previous findings with SMV VLPs. On further investigation, we found that stool components promote this attachment, providing the first known observation that one or more components of human feces could promote and enhance norovirus attachment to histo-blood group antigens.

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Cuéllar-Cruz, Mayra. "The histo-blood group antigens of the host cell may determine the binding of different viruses such as SARS-CoV-2." Future Microbiology 16, no. 2 (January 2021): 107–18. http://dx.doi.org/10.2217/fmb-2020-0158.

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Viruses have caused the death of millions of people worldwide. Specifically, human viruses are grouped into 21 families, including the family of coronaviruses (CoVs). In December 2019, in Wuhan, China, a new human CoV was identified, SARS-CoV-2. The first step of the infection mechanism of the SARS-CoV-2 in the human host is adhesion, which occurs through the S glycoprotein that is found in diverse human organs. Another way through which SARS-CoV-2 could possibly attach to the host’s cells is by means of the histo-blood group antigens. In this work, we have reviewed the mechanisms by which some viruses bind to the histo-blood group antigens, which could be related to the susceptibility of the individual and are dependent on the histo-blood group.

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Khunjeli, Rabindra, Sanjeet Krishna Shrestha, Manan Karki, Brajendra Srivastava, and Ushab Rana Mohsin. "Radiological and Bronchoscopic Findings for the Better Yield of Tissue Diagnosis in Lung Malignancy." Medical Journal of Shree Birendra Hospital 13, no. 2 (August 3, 2015): 25–30. http://dx.doi.org/10.3126/mjsbh.v13i2.13112.

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Introduction: In flexible bronchoscopy, absence of endobronchial abnormality blinds the bronchoscopist towards the location of the lung lesion. Guided techniques for bronchoscopy are not available in Nepal. Hence, diagnostic yield is very low. There is need to find the factors to improve yield. This study evaluates the radiological and bronchoscopic findings that can help in histo-pathological yield.Methods: This retrospective study included 557 bronchoscopies done for the evaluation of lung malignancy. Radiological, bronchoscopic and histo-pathological abnormalities were classified and evaluated. The study aimed at finding the radiological and bronchoscopic factors commonly associated with positive yield in histopathology.Results: Among 557 subjects, 490 had abnormal chest X-ray. Mass lesion was seen in 252(45.24%), cavity in 19(3.41%), collapse in 93(16.69%), consolidation in 81(14.54%), pleural effusion in 28(5.02%) and fibrosis in 17(3.05%) subjects. Total of 314(56.37%) abnormal bronchoscopies included: endobronchial growth 200(35.9%), narrowing 66(11.84%), obstruction 107(19.27%) and ulcer 16(2.8%). Histopathology was positive in 198(35.54%) including 179 (32.13%) lung malignancies. The diagnostic yield for getting positive histopathology for the study population was 35.54%, for mass lesion was 40.47% and for abnormal bronchoscopy was 54.78%. Significant correlation was identified among mass lesion, endobronchial abnormality and positive histo-pathology. Central mass lesion, collapse and consolidation showed significant association with lung malignancy. Significant association was also identified between histo-pathology and endobronchial growth, obstruction and ulcer. Conclusions: The diagnostic yield increases with positive endobronchial abnormality. Presence of central lung lesion, collapse and consolidation favour positive yield of histo-pathology. Endobronchial growth, obstruction and ulcer are likely to yield malignant histopathology reports.

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Venkitaraman, Lakshmi, Anitha Kumari, and Smitha Paulson. "Clinical dielema-epithelial myoepithelial carcinoma- rare presentation." Indian Journal of Pathology and Oncology 9, no. 4 (December 15, 2022): 331–33. http://dx.doi.org/10.18231/j.ijpo.2022.079.

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To describe our experience with a case of epithelial myoepithelial carcinoma that was reported as two different entities and thus proved to be a challenging case.: Retrospective review of histo-pathological reports with detailed work up of final findings and treatment. Four year follow up of the patient shows successful treatment with no recurrence. High index of suspicion and detailed histo-pathological evaluation with IHC testing is needed in tumours presenting with mixed cell population.

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Vinayachandran, Divya, and Sathasivasubramanian Sankarapandian. "Salivary Duct Cyst: Histo-pathologic Correlation." Journal of Clinical Imaging Science 3 (April 30, 2013): 3. http://dx.doi.org/10.4103/2156-7514.111236.

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Non-neoplastic cysts of the salivary glands are uncommon and represent 2-5% of all salivary gland lesions. They are mainly mucoceles or salivary duct cysts. Unlike a mucocele, which is surrounded by granulation tissue, the salivary duct cyst is lined by epithelium. Salivary duct cysts are more common in the oral minor salivary glands and rarely occur in the major salivary glands, show a marked predilection for the superficial lobe of the parotid, and represent 10% of all salivary gland cysts. Neoplastic differentiation of the lining of the salivary duct cyst has been reported. We report a case of a salivary duct cyst of the left parotid gland, with a review of radiographic and histopathologic features.

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Shirato, Haruko. "Norovirus and Histo-Blood Group Antigens." Japanese Journal of Infectious Diseases 64, no. 2 (March 31, 2011): 95–103. http://dx.doi.org/10.7883/yoken.64.95.

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Journal articles on the topic 'HISCO'

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