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Books on the topic 'Histological Subtype'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Hu, Jing Hong. Cytometric and histological measurements of gross and subtle stimuli upon brain and melanoma tissue. Laurentian University, School of Graduate Studies, 2006.

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2

Histological subtypes of common cancers. International Agency for Research on Cancer, 1997.

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3

Gilbert, Mark R., and Roberta Rudà. Ependymal tumours. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199651870.003.0005.

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Ependymomas are uncommon central nervous system cancers that can arise in the supratentorial, infratentorial, or spinal cord region. Recently, there have been several seminal findings regarding the molecular profiles of ependymomas that have led to marked changes in the classification of this disease. In addition to the World Health Organization grading system that designates ependymomas based on histological appearance into grade I, II, or III, a new molecular classification with distinct entities within the three anatomical regions provides additional subtyping that has prognostic significan

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4

Chang, Ellen T., and Allan Hildesheim. Nasopharyngeal Cancer. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0026.

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The main epithelial malignancy arising in the nasopharynx is nasopharyngeal carcinoma (NPC). Although rare throughout most of the world, NPC has a unique geographic distribution, with high-risk endemic areas in southern China and parts of Southeast Asia, intermediate incidence rates elsewhere in Southeast Asia, North Africa, the Arctic, the Middle East, and among Asian and Pacific Islander migrants, and very low risk in other areas. The great majority of NPC cases worldwide are non-keratinizing tumors; these predominate in endemic, high-incidence areas and comprise up to half of tumors in low-

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5

Blot, William J., and Robert E. Tarone. Esophageal Cancer. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0030.

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Cancer of the esophagus is the eighth most common malignancy worldwide in terms of incident cases and the sixth most common for cancer deaths. The two main histopathologic subtypes, esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EADC), have strikingly different clinical and epidemiologic features. ESCC occurs throughout the esophagus and is the most common histologic subtype globally; over 90% of cases in the traditionally high-risk regions of Eastern Asia and Eastern and Southern Africa are ESCC. The incidence of ESCC is decreasing worldwide. In some high-risk areas

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6

Ajithkumar, Thankamma, Ann Barrett, Helen Hatcher, and Natalie Cook. Bone tumours and soft tissue sarcomas. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235636.003.0012.

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Primary malignant tumours of bone are rare and comprise a large number of histological subtypes. • The most common are osteosarcoma, Ewing's family of tumours, and chondrosarcoma. Each of these has further subgroups which will be discussed in detail under their subheadings.• The remaining subgroups are exceptionally rare and include the presentation of spindle cell sarcoma of bone e.g. malignant fibrous histiocytoma (MFH), within the bone as a primary lesion. MFH of bone is treated as other primary bone tumours (Bramwell et al. 1999)....

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7

Roman, Eve, Tracy Lightfoot, Susan Picton, and Sally Kinsey. Childhood Cancers. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0059.

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This chapter addresses the wide range of histological and site-specific cancers that occur before age 25. It considers disease classifications, predisposing factors, and the epidemiology of the most common malignancies seen in children, and adolescents and young adults (AYAs). Cancer before age 25 is rare, accounting for < 2% of diagnoses in economically developed countries. The global burden of childhood cancers is, difficult to quantify, however, since over 80% of the world’s children and AYAs live in economically developing countries, where high morbidity/mortality from infectious diseas

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8

Mammoser, Aaron. Primary and Secondary Glioblastoma. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0127.

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Glioblastoma, formerly glioblastoma multiforme, is synonymous with WHO grade IV astrocytoma and is the most commonly diagnosed astrocytoma; it carries with it significant clinical, histologic, and molecular heterogeneity, with subtypes of the tumor and important new mutations associated with it characterized over the previous decade. Gene expression profiling has identified four tumor subgroups associated with specific mutational patterns, age of onset, and prognosis. The discovery of isocitrate dehydrogenase (IDH) mutations has led to further delineation between primary and secondary glioblas

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9

Frisch, Morten. Penile Cancer. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0055.

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Penile cancers are rare primary malignancies located on the glans, foreskin, or shaft of the penis, excluding the urethra. The vast majority of penile cancers are epithelial tumors representing histological subtypes of squamous cell carcinoma (SCC). Most penile SCCs are believed to develop through pre-invasive lesions known as penile intraepithelial neoplasia and penile carcinoma in situ. They account for 0.1%–0.3% of all incident cancers (excluding non-melanoma skin cancers) in the United States and other developed countries and up to 1% of all cancers in some countries in sub-Saharan Africa.

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10

Sanai, Nader. Low-Grade Gliomas. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190696696.003.0027.

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Low grade gliomas encompass multiple histologic diagnoses of primary brain tumors, most commonly grade 2 oligodendroglioma and grade 2 astrocytoma. This chapter presents a case of a patient with a left temporal low grade glioma who presented with seizures, which are a common presenting symptom for this tumor type. Management of patients with a newly diagnosed low grade glioma typically begins with maximal safe surgical resection for surgically accessible tumors. Surgical planning may involve functional imaging such as with fMRI. Genetic and molecular markers help distinguish subtypes of low gr

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11

Mirabello, Lisa, Rochelle E. Curtis, and Sharon A. Savage. Bone Cancers. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0042.

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Cancers arising from bone or cartilage account for about 0.2% of malignant neoplasms. They are histologically heterogeneous with multiple rare subtypes. Osteosarcoma and Ewing sarcoma occur primarily in children and young adults, whereas other bone cancers occur in older individuals. As a group, bone cancers have few known environmental risk factors, the exception being a strong association between therapeutic radiation and increased risk of osteosarcoma. The genetic etiology is also better understood in osteosarcoma, although there have been limited studies in other types of bone cancers. Thi

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12

Cutter, David, and Martin Scott-Brown. Diagnosis and staging of cancer. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0324.

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The accurate diagnosis of the precise type and stage of a malignancy is a vital part of cancer management. Treatment options and decisions vary significantly between various stages of the same malignancy (e.g. treatment with radical vs palliative intent) and also between specific histological subtypes of a cancer arising from the same organ (e.g. small-cell lung cancer vs non-small-cell lung cancer). It is therefore of critical importance that as much accurate information about each individual case is obtained. This is achieved with a variety of diagnostic procedures which allow the multidisci

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13

Crous-Bou, Marta, Immaculata de Vivo, and Pagona Lagiou. Endometrial Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0018.

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Lifestyle factors contribute appreciably to endometrial cancer risk, with obesity accounting for over one-third of incident cases in high-income societies. Unlike cervical cancer, which is a model of viral carcinogenesis, endometrial cancer is considered a model of hormonal carcinogenesis, as use of unopposed estrogens postmenopausally and obesity are the best-established risk factors. Endometrial cancer is also the only known malignancy for which cigarette smoking has been shown to confer protection. Risk reduction conferred by current smoking, past oral contraceptive use, childbearing, and p

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14

Healey, John H., and David McKeown. Orthopaedic surgery in the palliation of cancer. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0125.

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Metastatic spread of cancer to bone is frequent and causes pain, disability, and functional limitation. New understanding of the homing method of cancer cells to bone and the mechanism of cancer production of pain raise possible new treatment strategies. Non-surgical treatments such as chemotherapy and hormone therapy are effective in early disease. Bisphosphonates and inhibition of osteoprotegerin prevent progression of bone lesions and avoid pain, radiation, and surgery. Radiotherapy arrests disease and relieves pain in many cases. Surgery is needed when the bone is weak or fractured. It eff

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15

Berwick, Marianne, and Charles Wiggins. Soft Tissue Sarcoma. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0043.

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Soft tissue sarcoma (STS) is a rare tumor, occurring in approximately one to four of every 100,000 individuals worldwide. Soft tissue sarcomas can form anywhere in the body, including muscle, tendons, fat, blood vessels, lymph vessels, nerves, and tissues around joints. They are most common in the head, neck, arms, legs, trunk, and abdomen. Prognosis is generally poor, with a relative survival rate of approximately 65% at five years, with little difference by race. Approximately 11,930 cases and 4,870 deaths from STS occurred in the United States in 2015. The etiology of STS is still poorly un

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16

Michaud, Dominique, David Savitz, and Lorelei Mucci. Brain Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0024.

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cBrain tumors constitute an array of histologic types, the most common being meningioma and glioma. Unlike other cancers, both benign and malignant brain tumors are concerning for survival because of their anatomic location. Two-thirds of brain tumors are benign. The most well established risk factor is high dose ionizing radiation, based on studies of atomic bomb survivors as well as children treated for tinea capitis. In contrast, nonionizing radiation including from cellular telephones, is not a risk factor. Tobacco use does not appear to be associated with glioma or meningioma. There is fa

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