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Journal articles on the topic 'Histology of the kidney'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Fogo, Agnes B. "Kidney Histology." Clinical Therapeutics 34, no. 4 (2012): e11. http://dx.doi.org/10.1016/j.clinthera.2012.03.019.

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2

Denic, Aleksandar, Richard J. Glassock, and Andrew D. Rule. "Kidney Histology, Kidney Function, and Age." American Journal of Kidney Diseases 77, no. 3 (2021): 312–14. http://dx.doi.org/10.1053/j.ajkd.2020.10.011.

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3

Husain, S. Ali, Kristen L. King, Ibrahim Batal, et al. "Reproducibility of Deceased Donor Kidney Procurement Biopsies." Clinical Journal of the American Society of Nephrology 15, no. 2 (2020): 257–64. http://dx.doi.org/10.2215/cjn.09170819.

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Background and objectivesUnfavorable histology on procurement biopsies is the most common reason for deceased donor kidney discard. We sought to assess the reproducibility of procurement biopsy findings.Design, setting, participants, & measurementsWe compiled a continuous cohort of deceased donor kidneys transplanted at our institution from 1/1/2006 to 12/31/2016 that had at least one procurement biopsy performed, and excluded cases with missing biopsy reports and those used in multiorgan transplants. Suboptimal histology was defined as the presence of advanced sclerosis in greater than or

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Goesch, Torsten R., Nancy A. Wilson, Weifeng Zeng, et al. "Suppression of Inflammation-Associated Kidney Damage Post-Transplant Using the New PrC-210 Free Radical Scavenger in Rats." Biomolecules 11, no. 7 (2021): 1054. http://dx.doi.org/10.3390/biom11071054.

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Allograft kidney transplantation, which triggers host cellular- and antibody-mediated rejection of the kidney, is a major contributor to kidney damage during transplant. Here, we asked whether PrC-210 would suppress damage seen in allograft kidney transplant. Brown Norway (BN) rat kidneys were perfused in situ (UW Solution) with or without added 30 mM PrC-210, and then immediately transplanted into Lewis (LEW) rats. 20 h later, the transplanted BN kidneys and LEW rat plasma were analyzed. Kidney histology, and kidney/serum levels of several inflammation-associated cytokines, were measured to a

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Koper, Lindsey, Rachell L. Quarles, Janine M. Ziermann-Canabarro, Tashanti Bridgett, Paola Correa-Alfonzo, and Sulman J. Rahmat. "Anatomical and Histological Analyses of Rare Pancake Kidney." Anatomia 3, no. 3 (2024): 202–14. http://dx.doi.org/10.3390/anatomia3030016.

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During anatomical dissection of a female body donor at the Howard University College of Medicine, a rare renal anomaly was discovered. Detailed anatomical and histological analyses on this anomaly were compared to a normal kidney from another donor and previously published reports from a comprehensive literature review. Anatomical assessment confirmed the condition of pancake kidney, a rare form of completely fused, ectopic kidneys without an isthmus. Due to the lack of symptoms in patients with this condition and the limited number of published case reports, very little information is availab

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Naesens, Maarten, Dirk R. J. Kuypers, Katrien De Vusser, et al. "The Histology of Kidney Transplant Failure." Transplantation 98, no. 4 (2014): 427–35. http://dx.doi.org/10.1097/tp.0000000000000183.

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7

Naesens, M., D. Kuypers, P. Evenepoel, et al. "Proteinuria, Histology and Kidney-Allograft Survival." Transplantation 98 (July 2014): 78–79. http://dx.doi.org/10.1097/00007890-201407151-00245.

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8

Okoroama, Casmir E., Prince C. Unekwe, Linda C. Okoroama, Samuel U. Okparaoka та Godwin C. Akuodor. "Evaluation of the protective role of antioxidants: α-tocopherol, vitamin C, and quercetin, against ibuprofen-induced renal damage in male Wistar rats". International Journal of Basic & Clinical Pharmacology 12, № 5 (2023): 631–39. http://dx.doi.org/10.18203/2319-2003.ijbcp20232557.

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Background: Ibuprofen, commonly used in management of pains and inflammatory conditions, has been associated with renal damage. The protective role of antioxidants against Ibuprofen-induced renal damage in wistar rats were investigated in this study. Methods: The study was designed in two parts; first, to induce kidney damage and secondly, to determine protective role of antioxidants against ibuprofen-induced kidney injury. In the first phase, two groups of animals were used; one group treated with 120mg/kg ibuprofen daily for 14 days, while the other served as control and had distilled water.

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F, Eka p., and Sukarjati M.Kes. "PENGARUH PEMBERIAN EKSTRA ETHANOL DAUN TITHONIA DIVERSIFOLIA, EKSTRA ALLIUM SATIVUM dan CAMPURAN EKSTRA ALLIUM SATIVUM TERHADAP KERUSAKAN HISTOLOGI GINJAL dan HATI MENCIT HIPERGLIKEMIA." WAHANA 70, no. 1 (2018): 57–62. http://dx.doi.org/10.36456/wahana.v70i1.1569.

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Tithonia diversifolia and allium sativum are believed by the community to lower blood sugar levels. Research on safety test of Tifonia diversifolia extract and Allium sativum to histology of liver and kidney has not been done. The purpose of this research was to find out the effect of trimonic diversifolia extract extract and Allium extract as well as the extract and the second leaf mixture to histology structure of kidney and liver of mice with diabetes.This study was an experimental study in 45 mice sampled in divided into 11 groups of control groups extract tithonia diversifolia 50 mg / kg

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10

Calatroni, Marta, Filippo Consonni, Marco Allinovi, et al. "Prognostic Factors and Long-Term Outcome with ANCA-Associated Kidney Vasculitis in Childhood." Clinical Journal of the American Society of Nephrology 16, no. 7 (2021): 1043–51. http://dx.doi.org/10.2215/cjn.19181220.

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Background and objectivesANCA-associated vasculitis is extremely rare in children. We report the clinicopathologic features, long-term outcomes, and prognostic factors of a large pediatric cohort of patients with ANCA-associated kidney vasculitis.Design, setting, participants, & measurementsThis retrospective study included 85 consecutive patients with kidney biopsy specimen–proven ANCA-associated vasculitis from tertiary referral centers in Italy and Canada. Kidney biopsy specimens were categorized as focal, crescentic, sclerotic, or mixed, according to the Berden classification. The prog

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Ratna, Novia Kumala Dian Nur, Ani Setianingrum, Widi Nugroho, Ajeng Erika Prihastuti Haskito, and Aldila Noviatri. "SUPLEMENTASI YOGURT FORTIFIKASI KONSENTRASI BERTINGKAT EKSTRAK ROSELLA UNGU TERHADAP KADAR MALONDIALDEHIDA (MDA) DAN GAMBARAN HISTOLOGI GINJAL MENCIT." JURNAL KAJIAN VETERINER 10, no. 1 (2022): 1–12. http://dx.doi.org/10.35508/jkv.v10i1.5504.

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Purple roselle has ingredients such as organic acids, anthocyanins, polysaccharides, and flavonoids. The antioxidant content in purple roselle has benefits in preventing cell damage due to free radicals. This study was conducted to discoverthe effect of supplementation yogurt fortified with a graded concentration of purple roselle extract on MDA levels and histology of the kidney organs of mice. Laboratory experimental study using 16 male Balb-C mice divided into four groups. The control (C) group was not given any treatment. The treatment groups 1,2, and 3 (T1, T2, T3) were given fortified pu

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Callemeyn, Jasper, Evelyne Lerut, Henriette de Loor, et al. "Transcriptional Changes in Kidney Allografts with Histology of Antibody-Mediated Rejection without Anti-HLA Donor-Specific Antibodies." Journal of the American Society of Nephrology 31, no. 9 (2020): 2168–83. http://dx.doi.org/10.1681/asn.2020030306.

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BackgroundCirculating donor-specific anti-HLA antibodies (HLA-DSAs) are often absent in serum of kidney allograft recipients whose biopsy specimens demonstrate histology of antibody-mediated rejection (ABMR). It is unclear whether cases involving ABMR histology without detectable HLA-DSAs represent a distinct clinical and molecular phenotype.MethodsIn this multicenter cohort study, we integrated allograft microarray analysis with extensive clinical and histologic phenotyping from 224 kidney transplant recipients between 2011 and 2017. We used the term ABMR histology for biopsy specimens that f

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Apriliani, Nurul Safitri, and Muhammad Jafar Luthfi. "Comparative Anatomy and Histology of Black Pomfret (Formio niger) and Nile tilapia (Oreochromis niloticus) Kidney." Biology, Medicine, & Natural Product Chemistry 6, no. 1 (2017): 9. http://dx.doi.org/10.14421/biomedich.2017.61.9-12.

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Black pomfret and nile tilapia are belonging to order Perciformes. Both fish are live in different habitat. Black pomfret is marine water whereas nile tilapia is in freshwater. The purpose of the study was to determine anatomy and histology of the kidneys structures in both fishes. Histological preparations were done using paraffin method, with <em>Hematoxylin-Eosin</em> (HE) staining. The results, showed that Black pomfret and nile tilapia have y-shape kidney. Nile tilapia has darker red colour and softer texture than black pomfret kidney. Histologically, black pomfret and nile ti

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14

Lee, Yee Xin, See Meng Lim, Xin Qian Ng, et al. "Effects of Low-Protein Diet on Renal Oxidative Stress, Biochemistry and Histology in Weaned Rats." Sains Malaysiana 54, no. 3 (2025): 815–26. https://doi.org/10.17576/jsm-2025-5403-16.

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A low-protein diet (LPD) leads to low plasma protein and insufficient building blocks for normal kidney development, especially in children. This study aimed to determine the effects of short-term LPD on renal oxidative stress, biochemical profile and histologic changes in weaned rats. Three-week-old male and female Sprague Dawley rats were divided into the LPD group and the normal protein diet (NPD) group for 3 weeks. Renal oxidative stress, biochemical profile and histology were examined. Both male and female rats had significantly (p<0.05) lower body weight, smaller kidneys and higher ad

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15

Darajat, Zakia. "Study of Shark Kidney Histology (Carcharhinus sorrah)." Proceeding International Conference on Science and Engineering 1 (October 31, 2017): 67–69. http://dx.doi.org/10.14421/icse.v1.271.

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Shark is a fish widespread in the tropical Indo-Pacific Ocean with a depth of 75 to 130 meters. Shark is a cartilaginous fish (Elasmobranchii). The fish is an ancient animal species that are still alive and also have different characteristics with bony fishes. Research on the histology of the shark's kidneys is still rare. The purpose of this study was to describe the histology of the shark kidneys (Carcharhinus sorrah). In this study we used one individual shark (Carcharhinus sorrah) from Depok Beach, Yogyakarta. The method used in this research was paraffin method with Hematoxylin-Eosin stai

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Suo, Liye, Martha Caicedo Murillo, Brian Gallay, and Reut Hod-Dvorai. "Discrepancy Analysis between Histology and Molecular Diagnoses in Kidney Allograft Biopsies: A Single-Center Experience." International Journal of Molecular Sciences 24, no. 18 (2023): 13817. http://dx.doi.org/10.3390/ijms241813817.

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Histology diagnosis is essential for the monitoring and management of kidney transplant patients. Nowadays, the accuracy and reproducibility of histology have been criticized when compared with molecular microscopy diagnostic system (MMDx). Our cohort included 95 renal allograft biopsies with both histology and molecular diagnoses. Discrepancies between histology and molecular diagnosis were assessed for each biopsy. Among the 95 kidney allograft biopsies, a total of 6 cases (6%) showed clear (n = 4) or borderline (n = 2) discrepancies between histology and molecular diagnoses. Four out of the

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Craig, S. S., C. Mader, and J. S. Bond. "Immunohistochemical localization of the metalloproteinase meprin in salivary glands of male and female mice." Journal of Histochemistry & Cytochemistry 39, no. 1 (1991): 123–29. http://dx.doi.org/10.1177/39.1.1701182.

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Meprin is a membrane-bound metalloproteinase which is expressed at high levels in the brush border membrane of proximal tubules of kidneys of some mouse strains (referred to as high meprin-activity mice). The mature active proteinase is not present in kidneys of many inbred strains of mice; however, these low meprin-activity mice possess a kidney protein that crossreacts with polyclonal antibodies prepared against meprin. In the present studies, immunohistochemical methods were used to determine the presence of meprin in liver, pancreas, spleen, testis, thymus, kidney, salivary glands, stomach

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18

Joshi, Roli, Deepa Deopa, DN Sinha, and AK Singh. "Prenatal glomerular changes during development of human foetal kidney." National Journal of Clinical Anatomy 05, no. 04 (2016): 202–8. http://dx.doi.org/10.1055/s-0039-3401617.

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Abstract Background and aims: The cortical glomerulus shows many developmental changes during fetogenesis. Nonnalhistologyofthe fetal glomerulus at various stages of development was studied to get insight into the morphology of fetal glomerulus. Fetal glomerular study is a necessity for correlation with increase in gestational age and pathological changes which may affect the normal functioning of kidneys in fetal life. Method: Dissection of 70 normal human fetuses was carried out and histological findings of glomerulus were noted with respect to the age of fetus. The histology of fetal kidney

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19

Akoul, Marwa. "Effect of Artemisia annua Extract on Kidney Functions and Histology in Experimental Diabetic Rats." Jurnal Biologi 2, no. 1 (2024): 11. http://dx.doi.org/10.47134/biology.v2i1.3316.

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This study sought to understand the impact of an alcoholic extract of Artemisia annua on kidney function in experimental diabetic rats. For this study, fifty adult male albino rats were randomly assigned to one of five groups: G1 received unrestricted access to food and water. G2: To induce diabetes, a single intravenous injection of STZ (60 mg/kg) is administered. The third group undergoes insulin subcutaneous injections for four weeks after each STZ injection. The fourth group takes Artemisia annua extract orally (by gavage) at a dose of 75 mg/kg for four weeks following each STZ injection.

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20

Alamsyah, Firman, Nisrina Firdausi, Subekti Evi Dwi Nugraheni, et al. "Effects of non-contact electric fields on kidney and liver histology in tumour-induced rats." F1000Research 12 (November 22, 2024): 117. http://dx.doi.org/10.12688/f1000research.110080.5.

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Background A novel modality of cancer treatment based on exposure to non-contact electric fields has been developed to reduce cancer incidence. However, the safety of the electric field exposure was not fully investigated. Therefore, This study aimed to observe the safety of electric field exposure on kidney and liver structures. Methods Female Sprague-Dawley rats were divided into one control group and three treatment groups. Animals were treated with 7,12-dimethylbenz[a]anthracene for mammary tumour induction and exposed to non-contact electric fields individually for 10 hours a day for thre

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Alamsyah, Firman, Nisrina Firdausi, Subekti Evi Dwi Nugraheni, et al. "Effects of non-contact electric fields on kidney and liver histology in tumour-induced rats." F1000Research 12 (January 8, 2024): 117. http://dx.doi.org/10.12688/f1000research.110080.4.

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Background A novel modality of cancer treatment based on exposure to non-contact electric fields has been developed to reduce cancer incidence. However, the safety of the electric field exposure was not fully investigated. Therefore, This study aimed to observe the safety of electric field exposure on kidney and liver structures. Methods Female Sprague-Dawley rats were divided into one control group and three treatment groups. Animals were treated with 7,12-dimethylbenz[a]anthracene for mammary tumour induction and exposed to non-contact electric fields individually for 10 hours a day for thre

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22

Martínez-Martínez, M. U., L. M. de G. Llamazares-Azuara, D. Martínez-Galla, et al. "Urinary sediment suggests lupus nephritis histology." Lupus 26, no. 6 (2016): 580–87. http://dx.doi.org/10.1177/0961203316669241.

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Objectives The objective of this paper was to evaluate correlations between kidney biopsy indexes (activity and chronicity) and urinary sediment findings; the secondary objective was to find which components of urinary sediment can discriminate proliferative from other classes of lupus nephritis. Methods Lupus nephritis patients scheduled for a kidney biopsy were included in our study. The morning before the kidney biopsy, we took urine samples from each patient. Receiver operating characteristic (ROC) curves were plotted to determine the area under the curve (AUC) of each test for detecting p

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23

Agi, Yola Alunsa, and Titrawani Titrawani. "Kidney Histology of Wistar Rats (Rattus norvegicus Berkenhout 1769) Due to White Coffee." Jurnal Biologi UNAND 9, no. 2 (2021): 60. http://dx.doi.org/10.25077/jbioua.9.2.60-67.2021.

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Coffee is a drink that is very popular with the people of Indonesia and in other countries. Coffee has many benefits but on the other hand, coffee can also damage health, the dangerous content in coffee is caffeine and cafeeic acid. The effect of coffee consumption is still a matter of controversy, one of which is the effect on the kidneys because the kidneys are the main excretory organ for removing metabolic waste from the body. The kidney is the second organ after the liver, which is most often the target of damage by chemicals. This study aims to determine the effect of multilevel doses of

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Domingo, M., C. Einig, E. Eigenbrodt, and M. Reinacher. "Immunohistological demonstration of pyruvate kinase isoenzyme type L in rat with monoclonal antibodies." Journal of Histochemistry & Cytochemistry 40, no. 5 (1992): 665–73. http://dx.doi.org/10.1177/40.5.1374093.

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Four monoclonal antibodies (MAb) specific for the L-type isoenzyme of rat pyruvate kinase (L-PK) were produced and characterized. They detect at least two different epitopes of the isoenzyme, as shown in interference binding assay and Western blot analysis after peptide mapping. The MAb were used in immunohistology to demonstrate the L-PK isoenzyme in paraffin-embedded normal rat tissues. L-PK was found only in hepatocytes, kidney proximal tubules, islet cells of pancreas, and epithelial cells of the villi of small intestine. The content of L-PK in hepatocytes was often lower in the periportal

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Lozanoff, Scott, Jayne Johnston, Wenbin Ma, and Claude Jourdan–Le Saux. "Immunohistochemical Localization of Pax2 and Associated Proteins in the Developing Kidney of Mice with Renal Hypoplasia." Journal of Histochemistry & Cytochemistry 49, no. 9 (2001): 1081–97. http://dx.doi.org/10.1177/002215540104900903.

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Pax2 has been identified as a key regulatory protein associated with renal developmental malformations. The purpose of this study was to determine whether Pax2 protein expression, and that of other proteins important for normal renal development, is abnormally distributed in the prenatal kidney of the Brachyrrhine ( Br) mouse that displays heritable renal hypoplasia. Embryonic 3H1 +/+ and Br/Br mice were collected between E11.0 and E18.0. Routine light microscopy and immunohistochemical analysis using antibodies to Pax2, E-cadherin, fibronectin, laminin, and Type IV collagen were applied to se

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26

Alam, S. R., G. H. Tse, C. Stirrat, et al. "Nanoparticle Enhanced MRI Scanning to Detect Cellular Inflammation in Experimental Chronic Renal Allograft Rejection." International Journal of Molecular Imaging 2015 (April 14, 2015): 1–8. http://dx.doi.org/10.1155/2015/507909.

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Objectives. We investigated whether ultrasmall paramagnetic particles of iron oxide- (USPIO-) enhanced magnetic resonance imaging (MRI) can detect experimental chronic allograft damage in a murine renal allograft model. Materials and Methods. Two cohorts of mice underwent renal transplantation with either a syngeneic isograft or allograft kidney. MRI scanning was performed prior to and 48 hours after USPIO infusion using T2∗-weighted protocols. R2∗ values were calculated to indicate the degree of USPIO uptake. Native kidneys and skeletal muscle were imaged as reference tissues and renal explan

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27

Akosman, Murat, İsmail Türkmenoğlu, Aysun Demirkan, Vural Özdemir, and Mehmet Akalan. "Morphological Effects of Heat Stress on Cattle Kidney." Journal of Morphological Sciences 35, no. 02 (2018): 122–24. http://dx.doi.org/10.1055/s-0038-1669431.

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Introduction Cattle kidney is an interesting organ because of its individual morphological structure and the mobility of the left kidney. The effects of heat stress on animal yield have been previously researched. However, no data could be obtained during the literature research about the effects of heat stress on the morphological structure of cattle kidneys. Materials and Methods In the present study, morphometric measurements were performed on the left and right kidneys of male and female Holstein cattle. The kidney samples were collected in the summer and winter seasons to assess the effec

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Hasumi, Hisashi, Masaya Baba, Yukiko Hasumi, et al. "Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn." Proceedings of the National Academy of Sciences 112, no. 13 (2015): E1624—E1631. http://dx.doi.org/10.1073/pnas.1419502112.

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Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. Recent studies have revealed potential functions for Flcn in kidney; however, kidney-specific functions for Fnip1 and Fnip2 are unknown. Here we demonstrate that Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn. We observed no detectable phenotype in Fnip2 knockout mice, whereas Fnip1 deficiency produced phenotypes similar to those seen in Flcn-deficient mice in multiple organs, but not in kidneys. We found that abs

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Allon, Michael, Silvio H. Litovsky, Jason Chieh Sheng Tey, et al. "Abnormalities of vascular histology and collagen fiber configuration in patients with advanced chronic kidney disease." Journal of Vascular Access 20, no. 1 (2018): 31–40. http://dx.doi.org/10.1177/1129729818773305.

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Introduction: Several histologic features have been identified in the upper-extremity arteries and veins of patients with advanced chronic kidney disease, which may affect arteriovenous fistula maturation. However, it is unclear whether these chronic kidney disease vascular features are abnormal. Methods: We obtained upper-extremity arterial and venous specimens from 125 advanced chronic kidney disease patients undergoing arteriovenous fistula creation and from 15 control subjects. We quantified medial fibrosis, micro-calcification, and intimal hyperplasia with appropriate histology stains. We

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Alamsyah, Firman, Nisrina Firdausi, Subekti Evi Dwi Nugraheni, et al. "Effects of non-contact electric fields on kidney and liver histology in tumour-induced rats." F1000Research 12 (May 25, 2023): 117. http://dx.doi.org/10.12688/f1000research.110080.2.

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Background: A novel modality of cancer treatment based on exposure to non-contact electric fields has been developed to reduce the cancer incidence. However, the safety of this electric field exposure on vital organs has not been fully investigated. Therefore, the purpose of this study was to observe the safety of the electric field exposure on kidney and liver structures. Methods: Female Sprague-Dawley rats were divided into one control group and three treatment groups. Animals were treated with 7,12-dimethylbenz[a]anthracene for mammary tumour induction and exposed to non-contact electric fi

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Kamar, Nassim, Chakib Maaroufi, Céline Guilbeau-Frugier, et al. "Do kidney histology lesions predict long-term kidney function after liver transplantation?" Clinical Transplantation 26, no. 6 (2012): 927–34. http://dx.doi.org/10.1111/j.1399-0012.2012.01682.x.

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Motojima, Masaru, Sho Tanimoto, Masato Ohtsuka, Taiji Matsusaka, Tsutomu Kume, and Koichiro Abe. "Characterization of Kidney and Skeleton Phenotypes of Mice Double Heterozygous for Foxc1 and Foxc2." Cells Tissues Organs 201, no. 5 (2016): 380–89. http://dx.doi.org/10.1159/000445027.

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Foxc1 and Foxc2 play key roles in mouse development. Foxc1 mutant mice develop duplex kidneys with double ureters, and lack calvarial and sternal bones. Foxc2 null mice have been reported to have glomerular abnormalities in the kidney and axial skeletal anomalies. Expression patterns of Foxc1 and Foxc2 overlap extensively and are believed to have interactive roles. However, cooperative roles of these factors in glomerular and skeletal development are unknown. Therefore, we examined the kidneys and skeleton of mice that were double heterozygous for Foxc1 and Foxc2. Double heterozygotes were gen

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Kamar, N., C. Guilbeau-Frugier, A. Servais, et al. "Kidney histology and function in liver transplant patients." Nephrology Dialysis Transplantation 26, no. 7 (2010): 2355–61. http://dx.doi.org/10.1093/ndt/gfq718.

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Chamanza, Ronnie, Stuart W. Naylor, Vinicius Carreira, et al. "Normal Anatomy, Histology, and Spontaneous Pathology of the Kidney, and Selected Renal Biomarker Reference Ranges in the Cynomolgus Monkey." Toxicologic Pathology 47, no. 5 (2019): 612–33. http://dx.doi.org/10.1177/0192623319859263.

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To further our understanding of the nonhuman primate kidney anatomy, histology, and incidences of spontaneous pathology, we retrospectively examined kidneys from a total of 505 control Cynomolgus monkeys ( Macaca fascicularis; 264 male and 241 females) aged 2 to 6 years, from toxicity studies. Kidney weights, urinalysis, and kidney-related clinical biochemistry parameters were also evaluated. Although the functional anatomy of the monkey kidney is relatively similar to that of other laboratory animals and humans, a few differences and species-specific peculiarities exist. Unlike humans, the ma

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Esposito, M., V. Varca, A. Simonato, C. Toncini, G. Carmignani, and L. Derchi. "Coexistence of Different Histotypes of Renal Carcinoma: Our Experience and Literature Review." Urologia Journal 76, no. 2 (2009): 130–32. http://dx.doi.org/10.1177/039156030907600219.

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The coexistence of multiple, synchronous primary tumors of different histology within the same kidney is a rare condition. We report herein a series of five patients with two tumors of different histology involving synchronously the same kidney. Materials and Methods We reviewed the pathology reports of a series of 381 patients who underwent surgery for primary renal tumors at our institution from 2000 to 2007. In the files of all patients with synchronous tumors of different histology, special attention was given to the results of imaging studies. Results Five out of 381 patients (1.37%) had

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Ilyas, Syafruddin. "Description of Kidney Histology of Mus Musculus After Giving Nano Hebal Rhodomyrtus tomentosa (Haramounting)." International Journal of Ecophysiology 1, no. 1 (2019): 26–33. http://dx.doi.org/10.32734/ijoep.v1i1.844.

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The objective of this study was to determine the description of kidney histology of Mus musculus after giving Nano Herbal Rhodomyrtus tomentosa (Haramonting). R.tomentosa (Haramonting) is made on a nanoscale using High Energy Milling (HEM). This research use the Completely Randomized Design (CRD), which consists of six groups of CMC 0.5% and Nano- R.tomentosa (Haramonting) at dosage of (100; 141,42; 200; 282,82; 400)mg/20g body weight. The kidneys were made into preparations by using the paraffin method and Hematoxylin Erlich-Eosin staining (HE). The results of histological kidneys showed that

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Kumar, Vikash, Chun Yang, and Allen W. Cowley. "Temporal Expression and Cellular Localization of PAPPA2 in the Developing Kidney of Rat." Journal of Histochemistry & Cytochemistry 68, no. 3 (2020): 209–22. http://dx.doi.org/10.1369/0022155420904478.

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PAPPA2 is a metalloproteinase which cleaves insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-5, and its role in pregnancy and postnatal growth is primarily studied. Using exclusion mapping, we reported a subcongenic (26-P) rat where a 0.71-Mbp region containing the pregnancy-associated plasma protein a2 ( Pappa2) allele of salt-insensitive Brown Norway (BN) was introgressed into Dahl saltsensitive (SS) genetic background, resulting in the reduction of salt sensitivity. Pappa2 was differentially expressed in the adult kidney of 26-P and SS rats. Here, the expression and cellular l

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Minuth, Will W. "In Search of Imprints Left by the Impairment of Nephrogenesis." Cells Tissues Organs 207, no. 2 (2019): 69–82. http://dx.doi.org/10.1159/000504085.

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Clinical aspects dealing with the impairment of nephrogenesis in preterm and low birth weight babies were intensely researched. In this context it was shown that quite different noxae can harm nephron formation, and that the morphological damage in the fetal kidney is rather complex. Some pathological findings show that the impairment leads to changes in developing glomeruli that are restricted to the maturation zone of the outer cortex in the fetal human kidney. Other data show also imprints on the stages of nephron anlage including the niche, the pretubular aggregate, the renal vesicle, and

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Loghman-Adham, Mahmoud, Carlos E. Soto, Tadashi Inagami, and Cirilo Sotelo-Avila. "Expression of Components of the Renin-angiotensin System in Autosomal Recessive Polycystic Kidney Disease." Journal of Histochemistry & Cytochemistry 53, no. 8 (2005): 979–88. http://dx.doi.org/10.1369/jhc.4a6494.2005.

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Hypertension is a common complication in children with autosomal recessive polycystic kidney disease (ARPKD) who have survived the neonatal period. No information is available regarding the mechanism of hypertension in this condition. The renin-angiotensin system (RAS) is thought to play a role in hypertension associated with the more common autosomal dominant polycystic kidney disease (ADPKD). Occasional reports have documented increased activity of the intrarenal RAS in ADPKD, with ectopic renin expression within cysts and dilated tubules. Because of similarities between ARPKD and ADPKD, we

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Guedes Jr, Francisco Sobreira, Deyvid Santos da Cruz, Marcela Marcondes Pinto Rodrigues, et al. "Renal histology and immunohistochemistry after acute hemorrhage in rats under sevoflurane and ketoprofen effect." Acta Cirurgica Brasileira 27, no. 1 (2012): 37–42. http://dx.doi.org/10.1590/s0102-86502012000100007.

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PURPOSE: To investigate the influence of intravenous nonselective cyclooxygenase inhibitor, ketoprofen (keto), on kidney histological changes and kidney cytokines, tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1), levels after hemorrhage of 30% of volemia (three times 10%, intervals of 10 min) in rats. METHODS: Under sevoflurane (sevo) anesthesia, sevo and sevo+keto groups (10 rats each) were instrumented for Ringer solution (5mL/kg/h) administration and mean arterial pressure (MAP) evaluation, plus keto (1.5mg/kg) administration in sevo+keto group in the beginning of anesthesia. Recta

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Febrianto, Suseno, Miftahurrahmah Miftahurrahmah, and Armaidi Darmawan. "PERBANDINGAN GAMBARAN MIKROSKOPIK KERUSAKAN HEPAR DAN GINJAL TIKUS WISTAR YANG DIBERI MADU INTRAABDOMINAL SEBAGAI ANTIADHESI." Journal of Medical Studies 2, no. 1 (2022): 26–35. http://dx.doi.org/10.22437/joms.v2i1.18090.

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ABSTRACT Background: Honey is a non-pharmacological agent that has various effects, one of which is anti-adhesion. In a previous study, Jambi forest honey administered intraperitoneally was proven to be used as an anti-adhesion after laparotomy. But like other traditional medicines, high doses of honey orally can cause damage to the liver and kidneys. Objectives: to investigate the effect of honey given intraperitoneally. Methods: This research is a laboratory experimental study that uses a randomized controlled design method using a post test only control group design pattern, where pre

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Ellis, Robert J., Keng Lim Ng, Hemamali Samaratunga, Sharon J. Del Vecchio, Simon T. Wood, and Glenda C. Gobe. "Multifocal Primary Neoplasms in Kidney Allografts: Evaluation of Two Cases." Journal of Kidney Cancer and VHL 3, no. 2 (2016): 14–22. http://dx.doi.org/10.15586/jkcvhl.2016.53.

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Renal cell carcinoma (RCC) is the fifth most common malignancy in kidney transplant recipients, with increased risk arising due to immunosuppression. De novo RCC occurrence in kidney allografts is much less common when compared with the native kidneys. Multifocal RCC in allograft kidneys is rarely described. In this report, we discuss two cases of de novo multifocal renal neoplasms in allograft kidneys. Case 1 had three distinct neoplastic lesions of >5 mm, and case 2 had four. Using the World Health Organization 2016 classification of adult renal tumours, case 1 had one clear-cell (cc) RCC

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Mustofa, Syazili, and Sarasmita Nirmala Dewi. "Rhizophora apiculata Bark Ethanolic Extracts Prevent Kidney Damage Caused by Cigarette Smoke in Male Rats." Sriwijaya Journal of Medicine 6, no. 1 (2023): 17–23. http://dx.doi.org/10.32539/sjm.v6i1.204.

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Rhizophora apiculata mangrove bark contains high levels of antioxidants, including triterpenoids, steroids, saponins, and tannins. The high antioxidant content can prevent oxidative stress, one of which is caused by free radicals from cigarette smoke. This research aimed to determine the potential of Rhizophora apiculata mangrove bark to protect against damage to the kidney organs of male white rats (Rattus novergicus) of the Sprague-Dawley strain exposed to cigarette smoke. This study used 25 mice divided into 5 groups for 30 days, namely group K(-), which was not given exposure to cigarette

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Kattah, Andrea G., Sam Albadri, Mariam P. Alexander, et al. "Impact of Pregnancy on GFR Decline and Kidney Histology in Kidney Transplant Recipients." Kidney International Reports 7, no. 1 (2022): 28–35. http://dx.doi.org/10.1016/j.ekir.2021.10.010.

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Ohashi, Y., G. Thomas, S. Nurko, et al. "Association of Metabolic Syndrome With Kidney Function and Histology in Living Kidney Donors." American Journal of Transplantation 13, no. 9 (2013): 2342–51. http://dx.doi.org/10.1111/ajt.12369.

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Salim, Hotimah, Evi Sylvia Awwalia, and Ilham Putera Alam. "Protective Effect of Nigella sativa Seed Extract on Alloxan-Induced Mice Kidney Histology." WMJ (Warmadewa Medical Journal) 7, no. 2 (2022): 70–73. http://dx.doi.org/10.22225/wmj.7.2.4768.70-73.

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Abstract  Nigella sativa (N. sativa) has been used in traditional medicine, and several studies have been performed in the last decades to reveal its effects of it on different medical disorders such as diabetes, dyslipidemia, hypertension, and obesity. This study aimed to evaluate the effects of Nigella sativa extract in an alloxan-induced mice model. This research was a true experimental post-test-only control group design. Eight-weeks old male Mus musculus were treated with alloxan (150 mg/ kg) by a single intraperitoneal injection to induce diabetes mellitus. At three days of injecti

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Spaliviero, Massimiliano, Kelly Lynn Stratton, Timothy F. Donahue, et al. "Fluorescence in situ hybridization (FISH) and array-comparative genomic hybridization (a-CGH) from percutaneous needle biopsy compared to renal mass histology." Journal of Clinical Oncology 31, no. 6_suppl (2013): 471. http://dx.doi.org/10.1200/jco.2013.31.6_suppl.471.

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471 Background: Image-guided percutaneous needle biopsies are increasingly utilized for the diagnosis of renal tumors. Histologic diagnosis of renal mass subtypes, including malignant clear cell (ccRCC), papillary (pRCC), chromophobe (chrRCC) renal cell carcinoma, and benign oncocytomas (OC) can be challenging due to the low cellularity and damaged architecture of needle biopsy specimens. However, each subtype exhibits unique genetic aberrations that can assist in histologic classification and potentially assist in guiding management decisions. We report our initial experience correlating rena

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Kramer, Jan, Ralf Schwanbeck, Horst Pagel, Figen Cakiroglu, Jürgen Rohwedel та Ursula Just. "Inhibition of Notch Signaling Ameliorates Acute Kidney Failure and Downregulates Platelet-Derived Growth Factor Receptor β in the Mouse Model". Cells Tissues Organs 201, № 2 (2016): 109–17. http://dx.doi.org/10.1159/000442463.

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Ischemic acute kidney injury (AKI) is associated with high morbidity and frequent complications. Repeated episodes of AKI may lead to end-stage renal failure. The pathobiology of regeneration in AKI is not well understood and there is no effective clinical therapy that improves regeneration. The Notch signaling pathway plays an essential role in kidney development and has been implicated in tissue repair in the adult kidney. Here, we found that kidneys after experimental AKI in mice showed increased expression of Notch receptors, specifically Notch1-3, of the Notch ligands Jagged-1 (Jag1), Jag

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Salido, E. C., L. Barajas, J. Lechago, N. P. Laborde, and D. A. Fisher. "Immunocytochemical localization of epidermal growth factor in mouse kidney." Journal of Histochemistry & Cytochemistry 34, no. 9 (1986): 1155–60. http://dx.doi.org/10.1177/34.9.2426343.

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Epidermal growth factor (EGF) was originally isolated from mouse submandibular glands (SMG). However, SMG removal failed to lower circulating EGF, and large amounts of EGF have been found in mouse urine. In addition, the presence of pre-pro-EGF mRNA in mouse kidney has recently been reported by others. Kidneys may therefore represent an alternate source of EGF. In the present study, we investigated the immunocytochemical localization of EGF in mouse kidney. Male and female adult Swiss Webster mice were fixed by perfusion with 4% paraformaldehyde or Zamboni's fixative, the kidneys were frozen,

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Hlushchuk, Ruslan, Cédric Zubler, Sébastien Barré, et al. "Cutting-edge microangio-CT: new dimensions in vascular imaging and kidney morphometry." American Journal of Physiology-Renal Physiology 314, no. 3 (2018): F493—F499. http://dx.doi.org/10.1152/ajprenal.00099.2017.

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In the last decades, the contrast-enhanced micro-computed tomography (micro-CT) imaging of a whole animal kidney became increasingly important. The visualization was mainly limited to middle-sized vessels. Since modern desktop micro-CT scanners provide the necessary detail resolution, we developed an approach for rapid visualization and consistent assessment of kidney vasculature and glomeruli number. This method is based on μAngiofil, a new polymerizing contrast agent with homogenous X-ray absorption, which provides continuous filling of the complete vasculature and enables correlative imagin

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