Relevant bibliographies by topics / Histostructure

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  1. Journal articles
  2. Book chapters
  3. Conference papers

Academic literature on the topic 'Histostructure'

Author: Grafiati
Published: 4 June 2025
Last updated: 23 June 2025

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Journal articles on the topic "Histostructure"

1

O. A., Zayseva, Makhsumov Sh. M., Djanaev G. Yu., and Mamadaliev Sh. M. "Effect of HYD Drugs on Hemolytic Anemia Induced by Phenylhydrazine Hydrochloride." European Journal of Medical Genetics and Clinical Biology 1, no. 1 (2023): 149–54. http://dx.doi.org/10.61796/jmgcb.v1i1.268.

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In conclusion, the conducted experiments showed that the histostructure of the vital internal organs of rats in the control and experimental groups was almost the same. At the same time, drug-related histomorphological changes in their histostructure were not noted. It should be noted separately that the study of the histostructure of the liver and kidney from the parenchymatous organs of the animals that received the studied tincture showed that some morphological signs indicating their functional activity appeared. Therefore, long-term administration of the antianemic compound - DOY tincture to the body does not cause chronic poisoning in animals and any negative reactions in the histostructure of vital internal organs and biochemical analyzes of peripheral blood.
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Zayseva, O.A. Makhsumov Sh.M. Djanaev G.Yu. Mamadaliev Sh.M. "EFFECT OF HYD DRUGS ON HEMOLYTIC ANEMIA INDUCED BY PHENYLHYDRAZINE HYDROCHLORIDE." INTERNATIONAL BULLETIN OF MEDICAL SCIENCES AND CLINICAL RESEARCH 3, no. 9 (2023): 46–52. https://doi.org/10.5281/zenodo.8368906.

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In conclusion, the conducted experiments showed that the histostructure of the vital internal organs of rats in the control and experimental groups was almost the same. At the same time, drug-related histomorphological changes in their histostructure were not noted. It should be noted separately that the study of the histostructure of the liver and kidney from the parenchymatous organs of the animals that received the studied tincture showed that some morphological signs indicating their functional activity appeared. Therefore, long-term administration of the antianemic compound - DOY tincture to the body does not cause chronic poisoning in animals and any negative reactions in the histostructure of vital internal organs and biochemical analyzes of peripheral blood.
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3

Vinogradov, Aleksandr Anatol'evich, and Evgeniya Sergeevna Simakova. "AGE-RELATED CHANGES IN RAT LIVER HYDRATION AND HISTOSTRUCTURE." Ulyanovsk Medico-biological Journal, no. 3 (September 26, 2022): 120–28. http://dx.doi.org/10.34014/2227-1848-2022-3-120-128.

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One of the aging hypotheses is based on the fact that the percentage of water in the human body decreases with age. To a greater extent, the loss of water affects the most energy-dependent organs, such as liver, which undergoes a number of structural compensatory-adaptive changes. The parameters of age-related changes are currently understudied. However, they should be taken into account when determining the actual organ transformations in experiments.
 The purpose of the study was to examine the change in the level of total water and liver histostructure in rats during a 75-day observation.
 Materials and Methods. The changes in the level of total water in the liver parenchyma were assessed in young outbred intact rats during 75-day observation. The authors examined liver histostructure on sections stained with hematoxylin-eosin and picrofuchsin (Van Gieson's stain).
 Results. A decrease in the level of total water in the rat liver parenchyma by 0.54±0.042 % was observed during a 75-day observation. At the same time, no visible changes were detected in the liver histostructure.
 Conclusion. During the trial a decrease in the level of total water in the liver of intact animals was observed. It did not affect the change in liver histostructure.
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Meyramov, Gabit Gabdullowich, Klaus-Dieter Kohnert, Altynay Zhuparovna Shaibek та ін. "Indirect method of histochemical assessment of insulin content in pancreatic β-cells". Bulletin of the Karaganda University. “Biology, medicine, geography Series” 109, № 1 (2023): 160–66. http://dx.doi.org/10.31489/2023bmg1/160-166.

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Methods for analysis the state of histostructure and insulin and zinc content in pancreatic tissue allow to estimate either a state of histostructure alone or visual insulin content in ß-cells. Zinc content indicating the content of deposited insulin and the ability of ß-cells to form this form of hormone is possible using an additional method that increases the volume of work and complicates investigation. Authors have proposed a method that allows to simultaneously evaluate both the state of the histostructure and the quantitative content of deposited insulin and zinc in ß-cells of the pancreas. It has been experimentally confirmed that both the aldehyde-fucshsin method of insulin staining and Dithizone method for staining of zinc-ions in ß-cells can be separately used simultaneously for quantitative analysis of the content of deposited insulin and zinc in ß-cells. It has been experimentally confirmed that both the aldehyde-fucshsin method of insulin staining and the Dithizone method of detecting zinc in ß-cells can be separately used simultaneously for quantitative analysis of the content of deposited insulin and zinc in ß-cells. The use of both methods allows not only to assess the state of the histostructure, but to assess the content and functional ability of ß-cells to synthesize insulin, as well as to form its deposited form using zinc.
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5

Volkova, L. A., A. N. Vetokh, N. A. Volkova, Z. Alabdallah, and А. А. Nikishov. "FEATURES HISTOSTRUCTURE ORGANS OF TRANSGENIC CHICKEN." Theoretical & applied problems of agro-industry 38, no. 5 (2018): 34–37. http://dx.doi.org/10.32935/2221-7312-2018-38-5-34-37.

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6

Tamm, Tamara I., Valentyn V. Nepomniashchyi, Sergey B. Pavlov, Ivan M. Mamontov, Olena A. Shakalova, and Olga B. Litvinova. "Histostructure of bone tissue after restoration of blood flow in patients with ischemic form of diabetic foot syndrome." Polski Merkuriusz Lekarski 52, no. 6 (2024): 630–37. https://doi.org/10.36740/merkur202406103.

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Aim: To study the histostructure of bone tissue in case of disruption of its blood supply and after restored blood flow in patients with ischemic form of diabetic foot syndrome. Materials and Methods: The histostructure of bone fragments in 25 patients with isolated ischemic form of diabetic foot syndrome was studied. Bone tissue biopsy specimens from 6 patients against the background of progressive ischemia were studied. In addition, the histostructure of bone tissue after revascularization with complete restoration of blood flow in 19 patients was studied. Results: The analysis of bone tissue biopsy specimens showed that disruption of blood supply of the limb tissues for a long time leads to impaired matrix calcification, decreased cortex thickness, widening of osteon channels and sparse trabecular network in the bone structure. Such changes were the signs of bone resorption that was not clinically or radiologically apparent. Revascularization with full restoration of blood flow promoted the appearance of signs of bone tissue regeneration in the form of vessel formation in bone and periosteum. Conclusions: Adequate blood flow is an important clinical factor contributing to the restoration of bone regeneration in patients with ischemic form of diabetic foot syndrome.
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7

Filimonova, G. N., N. I. Antonov, and A. A. Emanov. "Osteogenesis and Histostructure of Femoral Muscles When Modeling a Femoral Fracture with Immediate or Delayed Osteosynthesis Using an Interlocking Intramedullary Antegrade Rod." Journal Biomed, no. 2 (June 10, 2020): 78–88. http://dx.doi.org/10.33647/2074-5982-16-2-78-88.

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Interlocked intramedullary osteosynthesis is the most common method for treating femoral shaft fractures. The aim — to reveal specifi c characteristics of the histostructure of canine femoral muscles when healing femoral fractures under osteosynthesis using interlocking intramedullary reinforcement with an antegrade metal rod. Femoral shaft fractures were modelled in 9 mongrel dogs. The fractures were fi xed with an intramedullary rod. In Group I (n=4), osteosynthesis was started immediately after bone injury. In Group II (n=5), osteosynthesis was started 4 days after fracture (delayed osteosynthesis). M. biceps femoris and M. quadriceps femoris were studied. In Group I and Group II, bone healing occurred following 42 and 70 days, respectively. A unifi ed bone marrow cavity and cortical layer had been formed by day 70 and day 100 in Group I and Group II, respectively. The histostructure of M. quadriceps femoris in Group I remained largely unchanged throughout the experiment, while M. biceps femoris underwent the process of structural reorganization on days 42 and 70 of the experiment. The Group of delayed osteosynthesis demonstrated changes in the histostructure of both muscles, including an increased diversity of fi bre diameters, an increased number of nuclei in myocytes, fi brosis of the interstitial space and perimysial arterial vessels. These changes were more pronounced in M. biceps femoris. Three months after injury, the histostructure of the muscles under study, even in the Group of delayed osteosynthesis, had no signifi cant differences and tended to the intact norm. In femoral fractures, the earliest possible fi xation of bone fragments with an inter locking antegrade intramedullary rod is recommended. A complete bone healing in such cases occurs a month earlier than in those with delayed osteosynthesis. The femoral muscles of the anterior group are injured to a lesser extent than those of the posterior group.
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8

Pavlovich, S. I., N. G. Grushka, O. A. Kondratska, et al. "Histostructural Changes in Immunocompetent Organs, Liver, and Lungs During Experimental Endotoxemia Induced by Lipopolysaccharide." Fiziolohichnyĭ zhurnal 70, no. 5 (2024): 66–71. http://dx.doi.org/10.15407/fz70.05.066.

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The purpose of the work was to study morphological changes in immunocompetent organs, liver and lungs during experimental endotoxemia induced by lipopolysaccharide (LPS). The histological method with hematoxylin-eosin staining and subsequent microscopic analysis was used in the work. The histostructural damage to the immune system organs (thymus, spleen, lymph nodes) occurs in experimental endotoxemia caused by LPS. There is a circulatory disorder with morphological changes in all layers of the vascular walls. Necrobiotic and necrotic damage to organ cells was also revealed. The liver of experimental animals underwent especially pronounced changes in histostructure. Significant microcirculation disorders with dilation and congestion of vessels of various sizes and significant damage to endothelial cells were identified. Necrotic changes in hepatocytes were accompanied by a significant increase in stellate reticuloendotheliocytes and increased lymphocytic infiltration, which is the basis for liver dysfunction and the development of an inflammatory immune reaction. In conclusion, the data obtained on the morphological manifestations of endotoxemic damage can serve as the basis for the development of effective therapeutic approaches in the treatment of LPS-induced internal organ damage.
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9

Satybaldiev, M. A., A. M. Ergesheva, and A. E. Seytkulova. "HISTOSTRUCTURE OF INTRAMURAL LYMPHOID FORMATIONS OF THE HEART." Eurasian Medical Journal, no. 4 (2021): 29–33. http://dx.doi.org/10.52680/16948254_2021_4_29.

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10

Gubergrits, N. B., О. A. Krylovа, and М. C. Opikhailo. "Features of the pancreatic histostructure in chronic pancreatitis." Experimental and Clinical Gastroenterology 163, no. 3 (2019): 38–42. http://dx.doi.org/10.31146/1682-8658-ecg-163-3-38-42.

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Book chapters on the topic "Histostructure"

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Hryntsova, Nataliia. "EFFECT OF L-TOCOPHEROL-CORRECTOR ON MORPHO-FUNCTIONAL ADJUSTMENT OF RAT’S ADRENAL GLANDS UNDER CONDITIONS OF READAPTATION TO LONG-TERM EXPOSURE OF HEAVY METAL SALTS." In Science, technology, and innovation: the experience of European countries and prospects for Ukraine. Publishing House “Baltija Publishing”, 2021. http://dx.doi.org/10.30525/978-9934-26-190-9-2.

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The monograph presents a theoretical generalization and scientific solution of a comprehensive study of the structural components state of the mature rats adrenal cortex under conditions of adaptation to the long-term influence of heavy metal salts and correction with L-tocopherol. The experiment was carried out on 24 white sexually mature male rats at the age of 7-8 months. The animals of the experimental group consumed ordinary drinking water for 30 days with the corrector drug L-tocopherol after 90 days of receiving water saturated with a combination of salts of heavy metals: zinc (ZnSO4 7H2O) – 5 mg/l, (CuSO4 5H2O) – 1 mg/l, iron (FeSO4) – 10 mg/l, manganese (MnSO4 5H2O) – 0.1 mg/l, lead (Pb (NO3)2) – 0.1 mg/l and chromium (K2Cr2O7) – 0.1 mg/l. The keeping of animals and all manipulations over them were carried out in accordance with national and international bioethical standards. To study morphological rearrangements in the adrenal cortex, histological, morphometric, immunohistochemical and biochemical research methods were used. Sections were stained with hematoxylin-eosin, Einarson, and Van Gieson’s. The expression of the proliferation marker Ki-67 and the heat shock marker 90 (Hsp90α) was determined on dewaxed sections 4-5 μm thick according to the manufacturer’s recommendations. The restoration of the histostructure of the adrenal cortex testified to the development of adaptive and regenerative processes in the organ, aimed at neutralizing the stress response and a number of hypoxic phenomena caused by the longterm influence of heavy metal salts. Adaptive rearrangements affected morphological changes in all structural components of the adrenal glands of experimental animals: stromal, vascular, and parenchymal. The corrector drug L-tocopherol had a bright protective effect on the structural components of the adrenal glands, taking into account its antioxidant properties, membrane-protective effect, etc. The positive adaptive morphological rearrangements in the adrenal glands can include a slight compensatory hypertrophy of the adrenal cortex, an increase in the functional activity index of the glomerular and reticular zones, a decrease in the severity of the fibrous component of the connective tissue of the stroma, the disappearance of stromal edema, stabilization of the circulatory system and rheological properties of the blood, improvement of the cytoarchitectonics of all zones cortex, the appearance of mitotic figures in the cells. There was a significant improvement in the state of the chromatin network of the nuclei of corticocytes and the appearance of nucleoli in most of the nuclei. The mechanisms of endocrine regulation of adaptive processes after prolonged exposure to salts of heavy metals in the body of experimental animals also worked due to the activation of the synthesis of sex hormones. An increase in Hsp90α expression in adrenal corticocytes also indicated active adaptive processes in their cytoplasm aimed at restoring synthetic activity. Despite the positive rearrangements in the adrenal cortex, negative signs should also be noted, namely: stromal edema and moderate vascular plethora were still present in the reticular zone, although the severity of these morphological rearrangements decreased in comparison with the indicators of animals with a 90-day period of consumption of heavy metal salts. The positive dynamics of the development of adaptive processes in the adrenal glands suggests that in the future, an increase in the timing of readaptation with the use of L-tocopherol can positively affect the achievement of homeostasis in the organ and lead to full or partial compensation for the action of the damaging agent on the organism of experimental animals.
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Conference papers on the topic "Histostructure"

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Khokhlova, N. S. "MORPHOFUNCTIONAL CHANGES IN THE IMMUNOCOMPETENT ORGANS DURING THE ADAPTATION OF RABBITS TO CELL CONTENT TECHNOLOGY." In DIGEST OF ARTICLES ALL-RUSSIAN (NATIONAL) SCIENTIFIC AND PRACTICAL CONFERENCE "CURRENT ISSUES OF VETERINARY MEDICINE: EDUCATION, SCIENCE, PRACTICE", DEDICATED TO THE 190TH ANNIVERSARY FROM THE BIRTH OF A.P. Stepanova. Publishing house of RGAU - MSHA, 2021. http://dx.doi.org/10.26897/978-5-9675-1853-9-2021-23.

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The article presents histostructural changes in the popliteal lymph node, thymus and spleen, depending on the stage of adaptation in lactating rabbits. Changes in the leukocyte profile were established by stages of the adaptation process in rabbits during pregnancy and active lactopoiesis.
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Soynikov, N. V., V. V. Shevtsova, E. S. Zatolokina, A. S. Daineko, and K. S. Lavrova. "Krasnoyruzhskaya V.E., Mesnyankina E.A. Features of the histostructural organization of the uterus in female representatives of the rodent order." In SCIENCE OF RUSSIA: TARGETS AND GOALS. LJournal, 2019. http://dx.doi.org/10.18411/sr-10-06-2019-35.

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Azarnoosh, Marzieh, Marcus Stoffel, and Dieter Weichert. "Numerical Modelling and Experimental Validation of Intervertebral Discs." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-63534.

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Over the last several decades investigations of replacement material for intervertebral disc (IVD) have been an important topic in medical research. The challenge is to create materials whose mechanical behavior ideally matches that of the articular cartilage comprising the native discs. Thus, the study of articular cartilages underlying mechanical characteristics is a key issue for the successful development and refinement of replacement materials. Using both experimental and cartilage histostructural data, including fiber orientation, a visco-hyperelastic-diffusion (VHD) material model is developed and implemented. This allows us to numerically study the mechanical behavior of an IVD consisting of a cartilaginous ring surrounding a fluid core. In this work, a three dimensional finite element (FE) model is developed to simulate the behavior of an IVD under various loading conditions. Finally, model parameters are iteratively determined by comparing the simulation results to compression tests on corresponding discs performed in a MTS machine with a tempered nutrient solution.
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