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Journal articles on the topic 'HIT'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Prechel, Margaret, Abigail M. Hilby, and Jeanine M. Walenga. "Cross Reactivity of Heparin-Induced PF4 Antibodies with Heparin- Bound IL-8." Blood 112, no. 11 (2008): 3429. http://dx.doi.org/10.1182/blood.v112.11.3429.3429.

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Abstract Background: Heparin-Induced Thrombocytopenia (HIT) is caused by polyclonal antibodies, formed to conformational neoepitopes exposed in platelet factor 4 (PF4) bound to heparin (H). HIT antibodies are commonly measured by one of several commercially available ELISAs. The literature reports cases of clinical HIT and/or positive HIT antibody-mediated platelet activation tests in patients without antibodies detectable in PF4 based ELISAs, and suggests that antibodies to other chemokines, such as interleukin-8 (IL-8), may be involved. The current study was undertaken to characterize the fr

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2

Pouplard, Claire, Sandra Regina, Jean Baptiste Valentin, and Yves Gruel. "A New Enzyme Immuno-Assay That Only Detects IgG Antibodies to Heparin-PF4 Complexes (Zymutest HIA IgG®) Improves the Specificity of the Diagnosis of HIT without Loss of Sensitivity." Blood 110, no. 11 (2007): 2096. http://dx.doi.org/10.1182/blood.v110.11.2096.2096.

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Abstract Heparin-induced thrombocytopenia (HIT) is associated in most patients with the development of antibodies to heparin-modified platelet factor 4 (PF4). Commercial immuno-assays frequently detect these antibodies after cardiac surgery but only few patients develop clinical HIT. Therefore, platelet activation tests such as serotonin release assay (SRA) are necessary to ensure the diagnosis of HIT with high specificity. Another approach to increase diagnosis specificity could be to detect IgG antibodies which are of major clinical relevance since they are the only class able to directly ac

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3

Gedo, John E. "A Hit, a Hit, a Palpable Hit!" Contemporary Psychology: A Journal of Reviews 36, no. 10 (1991): 845–46. http://dx.doi.org/10.1037/030239.

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4

Pouplard, Claire, Dorothée Leroux, Sandra Regina, Jérôme Rollin, and Yves Gruel. "Effectiveness of a new immuno-assay for the diagnosis of heparin-induced thrombocytopenia and improved specificity when detecting IgG antibodies." Thrombosis and Haemostasis 103, no. 01 (2010): 145–50. http://dx.doi.org/10.1160/th09-04-0253.

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SummaryThe diagnosis of heparin-induced thrombocytopenia (HIT) is based on clinical criteria and biological assays. Most immunoassays detect antibodies (either IgG alone or additionally IgA and IgM) against PF4 immobilised in wells of microtiter plates with stoichiometric concentrations of polyanion (heparin or polyvinylsulfonate). We studied whether diagnostic sensitivity and/or specificity for HIT could be improved using a novel assay in which unfractionated heparin is immobilised alone to the microwells, with PF4 (and, potentially, other heparin-dependent antigen proteins) provided by addin

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5

Bender, Hanno. "Hit schlägt UTP-Behörde." Lebensmittel Zeitung 77, no. 28 (2025): 15. https://doi.org/10.51202/0947-7527-2025-28-015-1.

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Die Handelsgruppe Hit hat nicht gegen das Verbot „unfairer Handelspraktiken“ verstoßen. Das hat das OLG Düsseldorf entschieden. Auch Edeka wird vor dem Gericht gegen die Durchsetzungsbehörde BLE triumphieren.

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6

Bender, Hanno. "Hit hat gute Karten vor Gericht." Lebensmittel Zeitung 77, no. 19 (2025): 22. https://doi.org/10.51202/0947-7527-2025-19-022-1.

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7

Patrick, Jon D., and Susan Ieraci. "Good HIT and bad HIT." Medical Journal of Australia 198, no. 4 (2013): 205. http://dx.doi.org/10.5694/mja12.11350.

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8

Jones, George Fenwick. "Hit's Hard to Hit Hit." English Language Notes 41, no. 1 (2003): 80–82. http://dx.doi.org/10.1215/00138282-41.1.80.

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9

Ogden, Jeff. "Hit first and hit hard." Infosecurity Today 1, no. 1 (2004): 32–34. http://dx.doi.org/10.1016/s1742-6847(04)00020-5.

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10

Warkentin, Theodore E., and Mark A. Crowther. "When is HIT Really HIT?" Annals of Thoracic Surgery 83, no. 1 (2007): 21–23. http://dx.doi.org/10.1016/j.athoracsur.2006.07.006.

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11

Whitehead, Kevin J., Doruk Toydemir, Whitney Wooderchak-Donahue, et al. "Investigation of the Genetic Determinants of Telangiectasia and Solid Organ Arteriovenous Malformation Formation in Hereditary Hemorrhagic Telangiectasia (HHT)." International Journal of Molecular Sciences 25, no. 14 (2024): 7682. http://dx.doi.org/10.3390/ijms25147682.

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Telangiectases and arteriovenous malformations (AVMs) are the characteristic lesions of Hereditary Hemorrhagic Telangiectasia (HHT). Somatic second-hit loss-of-function variations in the HHT causative genes, ENG and ACVRL1, have been described in dermal telangiectasias. It is unclear if somatic second-hit mutations also cause the formation of AVMs and nasal telangiectasias in HHT. To investigate the genetic mechanism of AVM formation in HHT, we evaluated multiple affected tissues from fourteen individuals. DNA was extracted from fresh/frozen tissue of 15 nasal telangiectasia, 4 dermal telangie

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12

Krönert, Alrun. "Hit ersetzt Landgard durch Greenyard." Lebensmittel Zeitung 75, no. 4 (2023): 18. http://dx.doi.org/10.51202/0947-7527-2023-4-018-1.

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Die Hit-Supermärkte konzentrieren die Logistikdienstleistung für ihre Obst- und Gemüsebelieferung auf einen einzigen Partner. Das Rennen gemacht hat der belgische Fruchtriese Greenyard. Dessen Deutschland-Tochter Greenyard Fresh Germany hat sich gegen die Erzeugergenossenschaft Landgard durchgesetzt.

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13

Thind, Ravneet, Danielle Heidemann, Sundara Raman, and Philip Kuriakose. "Correlation Of Heparin Confirmatory Test (HCT) With Optical Density (OD) and Serotonin Release Assay (SRA) In The Diagnosis Of Heparin Induced Thrombocytopenia (HIT)." Blood 122, no. 21 (2013): 4754. http://dx.doi.org/10.1182/blood.v122.21.4754.4754.

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Introduction Heparin-induced thrombocytopenia (HIT) is a potentially fatal, thrombotic complication of heparin therapy mediated by antibodies to complexes between platelet factor 4 (PF4) and heparin. Accurate and rapid diagnosis with prompt commencement of therapy are imperative as delays in treatment are associated with an increasing risk of thrombosis, amputation, or death. On the flip side, initiation of therapy with direct thrombin inhibitors without laboratory confirmation carries a significant risk of bleeding. Two types of laboratory tests are available for detection of these antibodies

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14

Skornova, Ingrid, Tomas Simurda, Lucia Stanciakova, et al. "A Functional Assay for the Determination of Heparin-Induced Thrombocytopenia via Flow Cytometry." Diagnostics 13, no. 18 (2023): 3019. http://dx.doi.org/10.3390/diagnostics13183019.

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Heparin-induced thrombocytopenia (HIT) is a life-threatening complication of heparin therapy (both unfractionated heparin and low-molecular-weight heparin). In our study, we examined a group of 122 patients with suspected HIT. The samples of all patients were analyzed in the first step using an immunoassay (ID-PaGIA Heparin/PF4, Hemos1L-Acustar HIT IgG, ZYMUTEST HIA Monostrip IgG) to detect the presence of antibodies against heparin–PF4 complexes (platelet factor 4). When the immunoassay was positive, the sample was subsequently analyzed for HIT with a functional flow cytometry assay, the HITA

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15

Range, Melissa. "Hit." Ecotone 9, no. 2 (2014): 149–50. http://dx.doi.org/10.1353/ect.2014.0019.

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16

WOODRUFF, DAVID W. "HIT." Nursing Made Incredibly Easy! 4, no. 1 (2006): 53–55. http://dx.doi.org/10.1097/00152258-200601000-00009.

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17

Wicks, Les. "Hit." Antipodes 36, no. 2 (2022): 252. http://dx.doi.org/10.1353/apo.2022.a944865.

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18

Bennett, A. "HIT." Journal of Substance Use 6, no. 1 (2001): 49–50. http://dx.doi.org/10.1080/146598901750132090.

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19

Ash, C. "Hit 'Em Quick, Hit 'Em Strong." Science 338, no. 6104 (2012): 173. http://dx.doi.org/10.1126/science.338.6104.173-b.

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20

Mende, Jan, and Hanno Bender. "Hit bringt UTP-Regelwerk vor Gericht." Lebensmittel Zeitung 76, no. 22 (2024): 22. http://dx.doi.org/10.51202/0947-7527-2024-22-022-1.

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21

Ziemba, Jessica B., Zena Wolf, Matthew Weinstock, and Saja Asakrah. "Double-Hit and Triple-Hit Follicular Lymphoma." American Journal of Clinical Pathology 153, no. 5 (2020): 672–85. http://dx.doi.org/10.1093/ajcp/aqz208.

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Abstract Objectives To better characterize the clinicopathologic presentation and outcomes of follicular lymphoma with MYC and BCL2 and/or BCL6 rearrangements (double-hit and triple-hit follicular lymphoma), we present three cases from our institution and perform a literature review of 37 published cases. Methods Cases were identified using institutional SoftPath software and the MEDLINE database via the PubMed search engine. Clinical and pathologic data were collected with subsequent stratification by histologic grade and treatment for comparison. Results Similar to classic follicular lymphom

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22

Gruel, Yves, and Jerome Rollin. "Fibronectin: a “double hit” modulator in HIT?" Blood 133, no. 9 (2019): 891–92. http://dx.doi.org/10.1182/blood-2019-01-894295.

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23

Benz, Rudolf, and Joelle Tchinda. "Double hit, triple hit—look for it." Blood 121, no. 13 (2013): 2383. http://dx.doi.org/10.1182/blood-2012-10-451716.

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24

Keserű, György M., and Gergely M. Makara. "Hit discovery and hit-to-lead approaches." Drug Discovery Today 11, no. 15-16 (2006): 741–48. http://dx.doi.org/10.1016/j.drudis.2006.06.016.

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25

Yang, Xing, Jiangtao Bian, Zhengxin Liu, Shuai Li, Chao Chen, and Song He. "HIT Solar Cells with N-Type Low-Cost Metallurgical Si." Advances in OptoElectronics 2018 (January 18, 2018): 1–5. http://dx.doi.org/10.1155/2018/7368175.

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A conversion efficiency of 20.23% of heterojunction with intrinsic thin layer (HIT) solar cell on 156 mm × 156 mm metallurgical Si wafer has been obtained. Applying AFORS-HET software simulation, HIT solar cell with metallurgical Si was investigated with regard to impurity concentration, compensation level, and their impacts on cell performance. It is known that a small amount of impurity in metallurgical Si materials is not harmful to solar cell properties.

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26

Scarisbrick, I. A., and M. Rodriguez. "Hit-hit and hit-run: Viruses in the playing field of multiple sclerosis." Current Neurology and Neuroscience Reports 3, no. 3 (2003): 265–71. http://dx.doi.org/10.1007/s11910-003-0087-9.

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27

Yao, Yao, Shaoqing Xiao, Xiumei Zhang, and Xiaofeng Gu. "Simulation optimizing of n-type HIT solar cells with AFORS-HET." Modern Physics Letters B 31, no. 19-21 (2017): 1740025. http://dx.doi.org/10.1142/s0217984917400255.

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This paper presents a study of heterojunction with intrinsic thin layer (HIT) solar cells based on n-type silicon substrates by a simulation software AFORS-HET. We have studied the influence of thickness, band gap of intrinsic layer and defect densities of every interface. Details in mechanisms are elaborated as well. The results show that the optimized efficiency reaches more than 23% which may give proper suggestions to practical preparation for HIT solar cells industry.

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28

Dinsdale, Paul. "Direct hit." Nursing Standard 15, no. 47 (2001): 12–13. http://dx.doi.org/10.7748/ns.15.47.12.s34.

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29

Folk, Holly. "Hit Gyülekezete." Nova Religio 20, no. 3 (2017): 101–16. http://dx.doi.org/10.1525/nr.2017.20.3.101.

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In this Field Notes contribution, I report on one of the largest Pentecostal church networks in Central Europe. Led by charismatic pastor Sándor Németh, Faith Church reflects trends in the globalization of Pentecostalism and the regional experience of post-Communist countries. Faith Church (Hit Gyülekezete) embraces three distinctive theologies running through contemporary evangelicalism: the charismatic gifts associated with the Toronto Blessing; the prosperity gospel of the Word of Faith movement; and philo-Semitic Christian Zionism. The evening service I attended in Budapest was structured

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30

Holm, Liisa, and Chris Sander. "Enzyme HIT." Trends in Biochemical Sciences 22, no. 4 (1997): 116–17. http://dx.doi.org/10.1016/s0968-0004(97)01021-9.

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31

Bushman, Karl. "Early hit." American Journal of Medicine 92, no. 3 (1992): 313. http://dx.doi.org/10.1016/0002-9343(92)90082-m.

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32

Schöttle, Markus. "Export Hit." ATZelektronik worldwide 13, no. 3 (2018): 3. http://dx.doi.org/10.1007/s38314-018-0036-7.

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33

Zelikow, Philip. "Hit Men." Foreign Affairs 79, no. 6 (2000): 199. http://dx.doi.org/10.2307/20050035.

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34

Perkins, Sid. "Hit Again." Science News 167, no. 14 (2005): 211. http://dx.doi.org/10.2307/4016358.

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35

Spatz, Gregory. "Hit Me." New England Review 38, no. 4 (2017): 138–47. http://dx.doi.org/10.1353/ner.2017.0113.

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36

Yelena Chernenko. "UNSCHEDULED HIT." Current Digest of the Russian Press, The 76, no. 011 (2024): 17. http://dx.doi.org/10.21557/dsp.96635079.

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37

Strait, R., B. Susskind, and F. Finkelman. "Murine TRALI: 1-hit vs. 2-hit model." Human Immunology 66, no. 8 (2005): 18. http://dx.doi.org/10.1016/j.humimm.2005.08.029.

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38

O’Brien, Peggy. "Doing Shakespeare: “YoA! Hit! A Very Palpable Hit!”." English Journal 82, no. 4 (1993): 40–45. http://dx.doi.org/10.58680/ej19937855.

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39

Al Raizah, A., A. Almozaini, R. Abu Eishah, et al. "P1674: CLINICAL IMPACT OF NON-ADHERENCE TO HIT GUIDELINES: A DOUBLE HIT IN HIT." HemaSphere 6 (June 2022): 1555–56. http://dx.doi.org/10.1097/01.hs9.0000849552.25502.29.

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40

Lucic, Josip, Tamam Bakchoul, and Karina Althaus. "Daumenmikrothrombose/Daumennekrose eines Patienten mit heparininduzierter Thrombozytopenie." Transfusionsmedizin - Immunhämatologie, Hämotherapie, Immungenetik, Zelltherapie 10, no. 01 (2020): 25–28. http://dx.doi.org/10.1055/a-1010-1268.

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ZusammenfassungWir berichten über einen 81-jährigen Patienten, der unter der Therapie mit unfraktioniertem Heparin (UFH) in prophylaktischer Dosierung eine heparininduzierte Thrombozytopenie mit Mikrothromben und beginnender Nekrose entwickelt hat. Die Prophylaxe wurde mit UFH durchgeführt. An Tag 10 kam es zu einem Thrombozytenabfall um > 50%. Eine Daumennekrose weckte den Verdacht auf eine heparininduzierte Thrombozytopenie (HIT). Der 4T-Score zeigte eine hohe Wahrscheinlichkeit für eine HIT auf (7 Punkte). Da der Schnelltest positiv ausfiel, wurde eine therapeutische Antikoagulation mit

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41

Hofmann, Janine. "„Hinter der Marke muss Innovation stecken“." Lebensmittel Zeitung 73, no. 26 (2021): 81. http://dx.doi.org/10.51202/0947-7527-2021-26-081.

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42

Danzer, Steve C. "A Hit, a Hit—A Very Palpable Hit: Mild TBI and the Development of Epilepsy." Epilepsy Currents 19, no. 4 (2019): 261–63. http://dx.doi.org/10.1177/1535759719854758.

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43

Perry, Stephanie L., Thomas L. Ortel, and Nicole L. Whitlatch. "Anti-heparin/platelet factor 4 antibody optical density values and the confirmatory procedure in the diagnosis of heparin-induced thrombocytopenia." Thrombosis and Haemostasis 100, no. 10 (2008): 678–84. http://dx.doi.org/10.1160/th08-02-0118.

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SummaryLaboratory testing for heparin-induced thrombocytopenia (HIT) includes the highly sensitive, though less specific, heparin/ platelet factor 4 (PF4) ELISA. A confirmatory test with excess heparin is routinely performed on positive ELISA results to improve test specificity; the significance of a negative confirmatory result is unknown. The aim was firstly to evaluate the clinical utility of the PF4 ELISA confirmatory assay, secondly to examine the relationship between ELISA optical density (OD) value and clinical diagnosis of HIT, and thirdly to assess current practice at a tertiary care

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44

Warkentin, Theodore E. "Fondaparinux: does it cause HIT? can it treat HIT?" Expert Review of Hematology 3, no. 5 (2010): 567–81. http://dx.doi.org/10.1586/ehm.10.54.

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45

O'Brien, Peggy. "Doing Shakespeare: "Yo! A Hit! A Very Palpable Hit!"." English Journal 82, no. 4 (1993): 40. http://dx.doi.org/10.2307/820847.

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46

Lang, J. D., and J. M. Hickman-Davis. "One-hit, two-hit . . . is there really any benefit?" Clinical and Experimental Immunology 141, no. 2 (2005): 211–14. http://dx.doi.org/10.1111/j.1365-2249.2005.02853.x.

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47

"Black hats hit Red Hat." Network Security 2008, no. 9 (2008): 2. http://dx.doi.org/10.1016/s1353-4858(08)70102-8.

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48

Kindermann, Wilfried. "HIT wird zum Hit." Deutsche Zeitschrift für Sportmedizin 2013, no. 11 (2013). http://dx.doi.org/10.5960/dzsm.2013.102.

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49

Goto, Hisanori, Iyo Tanimura, Yujiro Nakano, Yumie Takeshita, and Toshinari Takamura. "Thyroid Arteriovenous Malformation in Hereditary Hemorrhagic Telangiectasia: Insights on Successful Noninvasive Imaging." JCEM Case Reports 2, no. 8 (2024). http://dx.doi.org/10.1210/jcemcr/luae138.

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Abstract Hereditary hemorrhagic telangiectasia (HHT) causes arteriovenous malformations (AVMs) in several organs. This report is the first to document and image a thyroid AVM complication in HHT. A 72-year-old woman with HHT was referred for thyroid nodule evaluation. Ultrasonography showed a hypervascularized nodule in the right thyroid lobe which was initially suspected to be malignant. However, 3-dimensional computed tomography angiography demonstrated a thyroid AVM with abnormal anastomosis of the superior thyroid artery and the inferior thyroid vein. In the formation of thyroid AVM, here,

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50

Willems, Gertjan. "Van Top-Hit Girl tot Het Dwaallicht." Brood & Rozen 23, no. 1 (2018). http://dx.doi.org/10.21825/br.v23i1.17332.

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