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Journal articles on the topic 'HIV associated with TB'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Hamada, Yohhei, Haileyesus Getahun, Birkneh Tilahun Tadesse, and Nathan Ford. "HIV-associated tuberculosis." International Journal of STD & AIDS 32, no. 9 (2021): 780–90. http://dx.doi.org/10.1177/0956462421992257.

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Tuberculosis (TB) remains a leading cause of morbidity and mortality among people living with HIV. HIV-associated TB disproportionally affects African countries, particularly vulnerable groups at risk for both TB and HIV. Currently available TB diagnostics perform poorly in people living with HIV; however, new diagnostics such as Xpert Ultra and lateral flow urine lipoarabinomannan assays can greatly facilitate diagnosis of TB in people living with HIV. TB preventive treatment has been underutilized despite its proven benefits independent of antiretroviral therapy (ART). Shorter regimens using

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&NA;. "HIV-associated TB." Inpharma Weekly &NA;, no. 1158 (1998): 4. http://dx.doi.org/10.2165/00128413-199811580-00004.

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Naidoo, Kogieleum, Kasavan Naidoo, Nesri Padayatchi, and Quarraisha Abdool Karim. "HIV-Associated Tuberculosis." Clinical and Developmental Immunology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/585919.

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The intersecting HIV and Tuberculosis epidemics in countries with a high disease burden of both infections pose many challenges and opportunities. For patients infected with HIV in high TB burden countries, the diagnosis of TB, ARV drug choices in treating HIV-TB coinfected patients, when to initiate ARV treatment in relation to TB treatment, managing immune reconstitution, minimising risk of getting infected with TB and/or managing recurrent TB, minimizing airborne transmission, and infection control are key issues. In addition, given the disproportionate burden of HIV in women in these setti

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BUSHNELL, G., N. L. STENNIS, A. M. DROBNIK, et al. "Characteristics and TB treatment outcomes in TB patients with viral hepatitis, New York City, 2000–2010." Epidemiology and Infection 143, no. 9 (2014): 1972–81. http://dx.doi.org/10.1017/s0950268814002970.

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SUMMARYLiterature surrounding the burden of and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in persons with tuberculosis (TB) disease remains limited and focused on populations outside the USA. Cross-matched New York City (NYC) TB and viral hepatitis surveillance data were used to estimate the proportion of NYC adults diagnosed with TB from 2000 to 2010 with a report of viral hepatitis infection and to describe the impact of viral hepatitis infection on TB treatment completion and death. For 9512 TB patients, HCV infection was reported in 4·2% and HBV

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Tamene, Wegene, Meseret Abebe, Liya Wassie, et al. "PDL1 expression on monocytes is associated with plasma cytokines in Tuberculosis and HIV." PLOS ONE 16, no. 10 (2021): e0258122. http://dx.doi.org/10.1371/journal.pone.0258122.

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Introduction PDL1 and its interaction with PD1 is implicated in immune dysfunction in TB and HIV. The expression of PDL1 on multiple subsets of monocytes as well as their associations with cytokines and microbial products have not been well studied. Method HIV (TB-HIV+), TB (TB+HIV-) and TB/HIV co-infected (TB+HIV+) patients as well as apparently healthy controls (TB-HIV-) were recruited. TB and HIV patients were treatment naïve while TB/HIV patients were both ART naïve and experienced but not yet started TB therapy. Monocyte subsets were evaluated for PDL1 expression by flow cytometry; plasma

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Walker, Naomi F., Charles Opondo, Graeme Meintjes, et al. "Invariant Natural Killer T-cell Dynamics in Human Immunodeficiency Virus–associated Tuberculosis." Clinical Infectious Diseases 70, no. 9 (2019): 1865–74. http://dx.doi.org/10.1093/cid/ciz501.

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Abstract Background Tuberculosis (TB) is the leading cause of mortality and morbidity in people living with human immunodeficiency virus (HIV) infection (PLWH). PLWH with TB disease are at risk of the paradoxical TB-associated immune reconstitution inflammatory syndrome (TB-IRIS) when they commence antiretroviral therapy. However, the pathophysiology is incompletely understood and specific therapy is lacking. We investigated the hypothesis that invariant natural killer T (iNKT) cells contribute to innate immune dysfunction associated with TB-IRIS. Methods In a cross-sectional study of 101 PLWH

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Siev, Michael, Douglas Wilson, Supreet Kainth, et al. "Antibodies against Mycobacterial Proteins as Biomarkers for HIV-Associated Smear-Negative Tuberculosis." Clinical and Vaccine Immunology 21, no. 6 (2014): 791–98. http://dx.doi.org/10.1128/cvi.00805-13.

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ABSTRACTSerology data are limited for patients with sputum smear-negative HIV-associated active tuberculosis (TB). We evaluated the serum antibody responses against the mycobacterial proteins MPT51, MS, and echA1 and the 38-kDa protein via enzyme-linked immunosorbent assay (ELISA) in South African (S.A.) HIV-positive (HIV+) smear-negative TB patients (n= 56), U.S. HIV+controls with a positive tuberculin skin test (TST+;n= 21), and S.A. HIV-negative (HIV−) (n= 18) and HIV+(n= 24) controls. TB patients had positive antibody reactivity against MPT51 (73%), echA1 (59%), MS (36%), and the 38-kDa pr

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Zhou, Yang, Hui Wang, Sha-xi Li, Gui-lin Yang, and Ying-xia Liu. "Analysis of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in HIV/TB Co-infected Patients During HAART." Infection International 3, no. 3 (2014): 122–28. http://dx.doi.org/10.1515/ii-2017-0086.

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Abstract Objectives To investigate the clinical features of tuberculosis (TB)-associated immune reconstitution inflammatory syndrome (TB-IRIS) in patients co-infected with HIV/TB or latent infection during highly active antiretroviral therapy (HAART). Methods HIV-infected patients treated in the Third People’s Hospital of Shenzhen, China between March 2012 and March 2013 were recruited, and divided into 3 groups: 1) HIV/TB co-infection group (n = 50), 2) HIV/ MTB latent infection group (n = 50), and 3) HIV infection group (n = 50), with 12-month follow-up. Patients in the HIV/TB co-infection g

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Pando, Maria A., Cristina De Salvo, Christian T. Bautista, et al. "Human immunodeficiency virus and tuberculosis in Argentina: prevalence, genotypes and risk factors." Journal of Medical Microbiology 57, no. 2 (2008): 190–97. http://dx.doi.org/10.1099/jmm.0.47492-0.

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The objective of this study was to determine the prevalence and genetic variability of human immunodeficiency virus type 1 (HIV-1) and other sexually transmitted infections (STIs) among 205 patients with clinical diagnosis of tuberculosis (TB) in Buenos Aires in 2001. Infections with hepatitis B virus (HBV), HIV-1, hepatitis C virus (HCV), Treponema pallidum and human T-cell lymphotropic virus types I/II were diagnosed in 37/187 (19.8 %), 35/205 (17.1 %), 22/187 (11.8 %), 13/187 (7.0 %) and 4/181 (2.2 %) patients, respectively. Almost one in three participants (33.1 %) presented at least one i

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He, Wenlong, Rui Li, and Yaogang Wang. "Progress in the Prevention and Treatment of AIDS Associated with Tuberculosis." Infection International 5, no. 2 (2016): 44–49. http://dx.doi.org/10.1515/ii-2017-0129.

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AbstractEpidemiological studies have shown that infection with the human immunodeficiency virus (HIV) is an influential risk factor for infection withMycobacterium tuberculosis(MTb), the rapid progression of the initial infection to active tuberculosis (TB), and the reactivation of latent TB infection. MTb infection is also one of the most common opportunistic infections in people with HIV, including AIDS patients receiving anti-retroviral therapy. Given the prevalence of HIV infection, the incidence of TB infection, which had begun to decline, is facing a severe situation. HIV associated with

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Moskaliuk, V. D., and T. R. Kolotylo. "RENTHENOLOGICAL CHARACTERISTICS OF HIV-INFECTION COMBINED WITH TUBERCULOSIS. MAIN CAUSES OF MORTALITY." Інфекційні хвороби, no. 4 (March 17, 2020): 10–14. http://dx.doi.org/10.11603/1681-2727.2019.4.10956.

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The purpose of the work is to analyze the X-ray and some laboratory changes of the groups of patients with HIV-infection combined with tuberculosis (TB) and TB monoinfection, as well as to determine the main causes of the mortality of such patients. Patients and methods. We examined 351 patients, in particular 217 HIV/TB-related infections and 134 cases of tuberculosis only. The HIV/TB group was divided into 3 subgroups depending on the time of TB attachment to HIV infection. Results. The most striking clinical symptomatology is typical for HIV/TB infected patients, compared to pat

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Gardezi, Syed Anees Ahmed, Syed Haider Tirmizi, Elleyyeen Avais, Muhammad Uzair, Muneeb Ur Rehman, and Hammad . "Prevalence and Associated Risk Factors of TB in People with HIV in Pakistani Population." Pakistan Journal of Medical and Health Sciences 17, no. 5 (2023): 101–3. http://dx.doi.org/10.53350/pjmhs2023175101.

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Background: Mycobacterium tuberculosis infects 1/3rd of the world’s population. The second most common cause of death globally is tuberculosis TB. It has resulted in more than 2 million deaths annually. Due to the immunodeficiency in HIV patients’ opportunistic infections can easily get through the human defence system. TB infection is among the most common opportunistic infection present in PLHIV. Aim: To check the prevalence and associated risk factors of TB in patients having HIV in Pakistani population. Study Design: Descriptive cross-sectional study. Methodology: 138 patients above 18 yea

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Kay, Alexander W., Helena Rabie, Elizabeth Maleche-Obimbo, Moorine Penninah Sekadde, Mark F. Cotton, and Anna M. Mandalakas. "HIV-Associated Tuberculosis in Children and Adolescents: Evolving Epidemiology, Screening, Prevention and Management Strategies." Pathogens 11, no. 1 (2021): 33. http://dx.doi.org/10.3390/pathogens11010033.

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Children and adolescents living with HIV continue to be impacted disproportionately by tuberculosis as compared to peers without HIV. HIV can impact TB screening and diagnosis by altering screening and diagnostic test performance and can complicate prevention and treatment strategies due to drug–drug interactions. Post-tuberculosis lung disease is an underappreciated phenomenon in children and adolescents, but is more commonly observed in children and adolescents with HIV-associated tuberculosis. This review presents new data related to HIV-associated TB in children and adolescents. Data on th

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Rutakingirwa, Morris K., Fiona V. Cresswell, Richard Kwizera, et al. "Tuberculosis in HIV-Associated Cryptococcal Meningitis is Associated with an Increased Risk of Death." Journal of Clinical Medicine 9, no. 3 (2020): 781. http://dx.doi.org/10.3390/jcm9030781.

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Tuberculosis (TB) and cryptococcal meningitis are leading causes of morbidity and mortality in advanced HIV disease. Data are limited on TB co-infection among individuals with cryptococcal meningitis. We performed a retrospective analysis of HIV-infected participants with cryptococcal meningitis from 2010–2017. Baseline demographics were compared between three groups: ‘prevalent TB’ if TB treated >14 days prior to cryptococcal meningitis diagnosis, ‘concurrent TB’ if TB treated ± 14 days from diagnosis, or ‘No TB at baseline’. We used time-updated proportional-hazards regression models to a

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Rocha, Andresa Carraro, Nailu Flor Chenini de Carvalho Reis, and Maria Jacirema Ferreira Gonçalves. "Factors associated with mortality or survival of patients with tuberculosis: an integrative review." Revista Eletrônica Acervo Saúde 13, no. 12 (2021): e9352. http://dx.doi.org/10.25248/reas.e9352.2021.

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Objective: To identify factors associated with mortality or survival of patients with isolated Tuberculosis (TB) or TB/HIV co-infection. Methods: A literature review was performed in the following databases: PubMed, Web of Science, Scopus, Health Virtual Library, and SciELO sing the following search terms: “Survival” OR “Mortality” AND “Epidemiological factors” OR “Epidemiological determinants” OR “Associated factors.” Recommendations of Preferred Reporting Items for Systematic Reviews and Meta-Analyzes methodology were used. Results: The factors associated with mortality or reduced survival w

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Stijnberg, Deborah, Eric Commiesie, Diana Marín, Ward Schrooten, Freddy Perez, and Mauro Sanchez. "Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study." Revista Panamericana de Salud Pública 43 (December 20, 2019): 1. http://dx.doi.org/10.26633/rpsp.2019.103.

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Objective. To identify socio-demographic and clinical factors associated with mortality among persons with tuberculosis (TB) and TB/HIV co-infection in Suriname. Methods. This was a retrospective cohort study using data from the national TB and HIV databases for 2010 – 2015. The survival probability of TB and TB/HIV co-infected patients was analyzed using the Kaplan-Meier estimates and the log-rank test. A Cox proportional hazard model was applied. Results. The study showed that HIV-seropositivity (aHR: 2.08, 95%CI: 1.48 – 2.92) and older age (aHR: 5.84, 95%CI: 3.00 – 11.4) are statistically a

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Dikobe, Wame, Mooketsi Molefi, Bornapate Nkomo, et al. "The utility of a modified W.H.O. TB screening tool among children at a Botswana child welfare clinic." African Health Sciences 21 (May 23, 2021): 64–71. http://dx.doi.org/10.4314/ahs.v21i.11s.

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Background: In high TB/HIV settings, the increased risk for TB amongst children exposed to HIV has been established through biomedical tests. Screening HIV exposed children for TB can improve early childhood TB detection and treatment. Objective: This study assessed the utility of a modified World Health Organization (WHO) tool by including HIV variables, to determine TB exposure amongst HIV exposed children presenting to a “Well Child” Clinic (CWC). Methods: Clinical data were obtained from medical records and/or from the caregivers of children presenting to CWC. Data was analyzed

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Dikobe, Wame, Mooketsi Molefi, Bornapate Nkomo, et al. "The utility of a modified W.H.O. TB screening tool among children at a Botswana child welfare clinic." African Health Sciences 21, no. 1 (2021): 64–71. http://dx.doi.org/10.4314/ahs.v21i1.11s.

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Background: In high TB/HIV settings, the increased risk for TB amongst children exposed to HIV has been established through biomedical tests. Screening HIV exposed children for TB can improve early childhood TB detection and treatment. Objective: This study assessed the utility of a modified World Health Organization (WHO) tool by including HIV variables, to determine TB exposure amongst HIV exposed children presenting to a “Well Child” Clinic (CWC). Methods: Clinical data were obtained from medical records and/or from the caregivers of children presenting to CWC. Data was analyzed

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Ahmed, Adnan, Fitsum Weldegebreal, Fikru Tebeje, and Yadeta Dessie. "Treatment outcomes of tuberculosis cases by HIV status in Haramaya General Hospital, Ethiopia: A retrospective cross-sectional study." Medicine 103, no. 18 (2024): e38034. http://dx.doi.org/10.1097/md.0000000000038034.

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Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection pose significant challenges to global health, particularly in achieving the target of ending TB. However, the impact of HIV status on TB treatment outcomes remains unclear, especially in eastern Ethiopia. This study aimed to assess the treatment outcomes of TB cases by HIV status and associated factors in Haramaya General Hospital from November 15 to December 30, 2022. A retrospective cross-sectional study was conducted, reviewing the TB registry and treatment cards of patients who received anti-TB treatment between September

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Philips, Jennifer A. "HIV-associated anaerobes ferment TB risk." Science Translational Medicine 9, no. 389 (2017): eaan3781. http://dx.doi.org/10.1126/scitranslmed.aan3781.

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do Nascimento, Charlene Troiani, Danilo Zangirolami Pena, Rogério Giuffrida, et al. "Prevalence and epidemiological characteristics of inmates diagnosed with infectious diseases living in a region with a high number of prisons in São Paulo state, Brazil." BMJ Open 10, no. 9 (2020): e037045. http://dx.doi.org/10.1136/bmjopen-2020-037045.

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ObjectiveTo determine the prevalence and epidemiological characteristics of inmates diagnosed with infectious diseases living in a region with a high number of prisons, São Paulo, Brazil.DesignThis is a retrospective and descriptive study conducted from November 2017 to October 2018.SettingPrisons located in the western and northwestern regions of São Paulo, Brazil.MethodsWe conducted a retrospective analysis on infectious diseases and coinfections (HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and tuberculosis (TB)) of inmates from 28 prisons. Inmates were previously diagnos

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Achkar, Jacqueline M., Elisabeth Jenny-Avital, Xian Yu, et al. "Antibodies against Immunodominant Antigens of Mycobacterium tuberculosis in Subjects with Suspected Tuberculosis in the United States Compared by HIV Status." Clinical and Vaccine Immunology 17, no. 3 (2010): 384–92. http://dx.doi.org/10.1128/cvi.00503-09.

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ABSTRACT The immunodominance of Mycobacterium tuberculosis proteins malate synthase (MS) and MPT51 has been demonstrated in case-control studies with patients from countries in which tuberculosis (TB) is endemic. The value of these antigens for the serodiagnosis of TB now is evaluated in a cross-sectional study of pulmonary TB suspects in the United States diagnosed to have TB, HIV-associated TB, or other respiratory diseases (ORD). Serum antibody reactivity to recombinant purified MS and MPT51 was determined by enzyme-linked immunosorbent assays (ELISAs) of samples from TB suspects and well-c

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Jadhav, Sushama, Aishwarya Nair, Pratik Mahajan, and Vijay Nema. "The Crosstalk Between HIV-TB Co-Infection and Associated Resistance in the Indian Population." Venereology 3, no. 4 (2024): 183–98. http://dx.doi.org/10.3390/venereology3040015.

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Extensive research on tuberculosis (TB) and HIV co-infection reveals the diverse prevalence and co-epidemic patterns across populations, necessitating tailored public health strategies. Co-infection is bidirectional; individuals with HIV are more susceptible to TB, and vice versa. Antiretroviral therapy (ART) and antituberculosis treatment (ATT) are critical for managing these conditions, but pose risks due to drug–pathogen and drug–drug interactions, potentially leading to immune reconstitution inflammatory syndrome (IRIS) in patients with HIV/AIDS. IRIS, often triggered by highly active anti

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Lenela, Maletsatsi, and Stephen Knight. "Effectiveness of early initiation of antiretroviral therapy in adults with HIV associated tuberculosis in Lesotho in 2012." Southern African Journal of Infectious Diseases 32, no. 3 (2017): 87–90. http://dx.doi.org/10.4102/sajid.v32i3.44.

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Background:Lesotho has a huge burden of human immunodeficiency virus associated tuberculosis (HIV-TB). In this study we compared the effectiveness of early versus late commencement of antiretroviral therapy (ART) in adults living with HIV-TB in Lesotho.Methods: Three out of 17 hospitals were randomly selected and data extracted from the hospitals’ tuberculosis (TB) treatment registers for 247 adults living with HIV-TB who completed TB therapy during the first quarter of 2012.Results: Eighty (32%) commenced ART early (4 weeks), 100 (41%) were started late (≥4 weeks) and 67 (27%) received no ART

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Goovaerts, Odin, Marguerite Massinga-Loembé, Pascale Ondoa, et al. "Lack of elevated pre-ART elastase-ANCA levels in patients developing TB-IRIS." PLOS ONE 15, no. 12 (2020): e0244800. http://dx.doi.org/10.1371/journal.pone.0244800.

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Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) in HIV-TB co-infected patients receiving antiretroviral therapy (ART) has been linked to neutrophil activation. Anti-neutrophil cytoplasmic antibodies (ANCAs) are also associated with neutrophil activation. Since ANCAs are reportedly skewed in TB and HIV infections, we investigated plasma levels of 7 ANCAs in TB-IRIS patients. Methods We retrospectively compared 17 HIV-TB patients who developed TB-IRIS with controls of similar CD4 count, age and gender who did not (HIV+TB+ n = 17), HIV-infected patients wi

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Karmakar, Suman, Surendra K. Sharma, Richa Vashishtha, et al. "Clinical Characteristics of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in North Indian Population of HIV/AIDS Patients Receiving HAART." Clinical and Developmental Immunology 2011 (2011): 1–9. http://dx.doi.org/10.1155/2011/239021.

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Background & Objective. IRIS is an important complication that occurs during management of HIV-TB coinfection and it poses difficulty in diagnosis. Previous studies have reported variable incidence of IRIS. The present study was undertaken to describe the pattern of TB-associated IRIS using recently proposed consensus case-definitions for TB-IRIS for its use in resource-limited settings.Methods. A prospective analysis of ART-naïve adults started on HAART from November, 2008 to May, 2010 was done in a tertiary care hospital in north India. A total 224 patients divided into two groups, one w

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Saeed, Muhammad, Shahida Hussain, Saba Riaz, et al. "GeneXpert Technology for the diagnosis of HIV-associated tuberculosis: Is scale-up worth it?" Open Life Sciences 15, no. 1 (2020): 458–65. http://dx.doi.org/10.1515/biol-2020-0052.

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AbstractRecent evaluations of the GeneXpert MTB/RIF assay for the simultaneous detection of Mycobacterium tuberculosis and drug resistance in less than 2 h have stimulated tremendous enthusiasm. This is the breakthrough that tuberculosis (TB) control has been waiting for. In this (retrospective review) case study, sputum samples from strongly suspected pulmonary tuberculosis patients were collected and assessed for the GeneXpert MTB/RIF assay for diagnosing TB and drug resistance in comparison with other tests, including Ziehl–Neelsen smear and Löwenstein–Jensen test. Of 3,784 cases, 5.7% (216

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Sharling, Lisa, Suzanne M. Marks, Michael Goodman, Terence Chorba, and Sundari Mase. "Rifampin-resistant Tuberculosis in the United States, 1998–2014." Clinical Infectious Diseases 70, no. 8 (2019): 1596–605. http://dx.doi.org/10.1093/cid/ciz491.

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Abstract Background Monoresistance to rifamycins necessitates longer and more toxic regimens for tuberculosis (TB). We examined characteristics and mortality associated with rifampin-monoresistant (RMR) TB in the United States. Methods We analyzed Mycobacterium tuberculosis culture-positive cases reported to the National TB Surveillance System (excluding California) between 1998 and 2014. We defined RMR TB found on initial drug susceptibility testing and possible acquired rifampin-resistant (ARR) TB. We assessed temporal trends in RMR TB. For both classifications of rifampin resistance, we cal

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Peltzer, Karl. "HIV risk behaviour among public primary healthcare patients with tuberculosis in South Africa." Southern African Journal of HIV Medicine 14, no. 3 (2013): 125–30. http://dx.doi.org/10.4102/sajhivmed.v14i3.65.

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Objective. To identify factors associated with HIV in tuberculosis (TB) patients in a public primary healthcare (PHC) setting in South Africa (SA).Method. Among 4 900 consecutively selected TB patients (54.5% men; women 45.5%) from 42 public PHC clinics in 3 districts in SA, a cross-sectional survey was performed to assess new TB and new TB retreatment patients within one month of anti-TB treatment.Results. The sample comprised 76.6% new TB patients and 23.4% TB retreatment patients. Of those who had tested for HIV, 59.9% were HIV-positive; 9.6% had never tested for HIV. In multivariate analys

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Biswas, M. Haider Ali, S. Abdus Samad, Tahera Parvin, M. Tusberul Islam, and Asep K. Supriatna. "Optimal Control Strategy to Reduce the Infection of Pandemic HIV Associated with Tuberculosis." Communication in Biomathematical Sciences 5, no. 1 (2022): 20–39. http://dx.doi.org/10.5614/cbms.2022.5.1.2.

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Tuberculosis (TB) and HIV/AIDS has become hazardous among communicable diseases and so as their co-infection in present era. HIV virus gradually weakens immune system in human body, and then TB infects with the assist of HIV/AIDS at any stage of the total infectious period. Today, HIV and tuberculosis (TB) are the main causes of mortality from infectious and chronic diseases. In this Study, we manifest a compartmental co-infection model including HIV and TB on the basis of their characteristics of disease transmission. The model is divided into 10 compartments, each with its own set of nonline

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Mehrian, Payam, Abtin Doroudinia, Moghadaseh Shams, and Niloufar Alizadeh. "Distribution and Characteristics of Intrathoracic Lymphadenopathy in TB/HIV Co-Infection." Infectious Disorders - Drug Targets 19, no. 4 (2019): 414–20. http://dx.doi.org/10.2174/1871526518666181016111142.

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Background: Intrathoracic Lymphadenopathy (ITLN) in Human Immunodeficiency Virus (HIV) infected patients may have various etiologies and prognoses. Etiologies of ITLN can be distinguished based on the distribution of enlarged lymph nodes. Sometimes tuberculosis (TB) is the first sign of underlying HIV infection. Objective: We sought to determine ITLN distribution and associated pulmonary findings in TB/HIV co-infection using Computed Tomography (CT) scan. Methods: In this retrospective, observational, cross-sectional study, chest CT scans of 52 patients with TB/HIV co-infection were assessed f

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Woldesemayat, Endrias Markos, and Zewtir Azeze. "Treatment outcome of tuberculosis at Dilla Referral Hospital, Gedeo Zone, southern Ethiopia: A retrospective study." PLOS ONE 16, no. 4 (2021): e0249369. http://dx.doi.org/10.1371/journal.pone.0249369.

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Background Tuberculosis (TB) is one of the major public health problems in Ethiopia. Determining treatment outcome of TB cases could help to understand the effectiveness of TB control efforts. The objective of this study was to assess TB treatment outcome and associated factors and determine the risk factors of death among TB cases who were on Directly Observed Treatment Short course (DOTS). Methodology We analyzed a retrospective data for TB cases who were on DOTS at Dilla Referral Hospital from July 2011- June 2016. The study population was TB cases with known HIV status and whose treatment

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Gizachew Beza, Mucheye, Emirie Hunegnaw, and Moges Tiruneh. "Prevalence and Associated Factors of Tuberculosis in Prisons Settings of East Gojjam Zone, Northwest Ethiopia." International Journal of Bacteriology 2017 (October 17, 2017): 1–7. http://dx.doi.org/10.1155/2017/3826980.

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Background. Tuberculosis, mainly in prisoners, is a major public health problem in Ethiopia where there is no medical screening during prison admission. This creates scarcity of TB data in such settings. Objective. To determine prevalence and associated factors of TB in prisons in East Gojjam Zone, Northwest Ethiopia. Methods. A cross-sectional study was conducted from February to May 2016 among 265 prisoners in three prison sites. Sputum was processed using GeneXpert MTB/RIF. Data were analyzed using SPSS version 20.0. Multivariable logistic regression was used; p values = 0.05 were considere

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Yuniati, Shinta Karina, and Tutik Kusmiati. "Factors Associated with Absence of Active Pulmonary Tuberculosis in HIV Patients with Latent Tuberculosis, Beyond Isoniazid Preventive Therapy." International Journal of Mycobacteriology 13, no. 3 (2024): 293–98. http://dx.doi.org/10.4103/ijmy.ijmy_146_24.

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Background: Tuberculosis (TB) is a leading cause of death in patients with human immunodeficiency virus (HIV)/AIDS. About 60% of HIV-positive individuals with latent TB infection (LTBI) develop active TB. Isoniazid preventive therapy (IPT) is recommended by the World Health Organization to prevent the progression of active TB in people living with HIV/AIDS (PLWHA). However, IPT implementation has been limited in some countries like Indonesia. The objective of this study was to assess the effect of IPT administration on the incidence of active TB in HIV patients with latent TB. Methods: This wa

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Makhkamova, Z. R., T. N. Golubova, E. A. Gerashchenko, E. I. Ivanova, and T. I. Bogatyreva. "Comparative analysis of epidemiology of HIV-associated tuberculosis in the Republic of Crimea and the Russian Federation for the period 2019– 2023." Bulletin Physiology and Pathology of Respiration, no. 96 (June 24, 2025): 87–95. https://doi.org/10.36604/1998-5029-2025-96-87-95.

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Introduction. The problem of HIV-associated tuberculosis (TB) remains relevant at both the international and national levels. Co-infection poses additional challenges for healthcare systems, as well as national and regional economics. Aim. To perform a comparative analysis of the epidemiological situation regarding HIV-associated tuberculosis in the Republic of Crimea (RC) and the Russian Federation (RF) during the period 2019–2023. Materials and methods. The study utilized official statistics on the incidence of TB and HIV infection, as well as the incidence, prevalence, and mortality of HIV-

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Adhikari, M., P. Jeena, R. Bobat, et al. "HIV-Associated Tuberculosis in the Newborn and Young Infant." International Journal of Pediatrics 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/354208.

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Each year, approximately 250 000 women die during pregnancy, delivery, or postpartum. Maternal mortality rates due to tuberculosis (TB) and HIV in Sub-Saharan Africa now supersede obstetric-related causes of mortality. The majority of cases occur in population-dense regions of Africa and Asia where TB is endemic. The vertical transmission rate of tuberculosis is 15%, the overall vertical transmission rate of HIV in resource-limited settings with mono- or dual-ARV therapy varies from 1.9% to 10.7%. If the millennium development goals are to be achieved, both HIV and TB must be prevented. The es

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Baluku, Joseph Baruch, Pallen Mugabe, Rose Mulwana, Sylvia Nassozi, Richard Katuramu, and William Worodria. "High Prevalence of Rifampicin Resistance Associated with Rural Residence and Very Low Bacillary Load among TB/HIV-Coinfected Patients at the National Tuberculosis Treatment Center in Uganda." BioMed Research International 2020 (July 25, 2020): 1–7. http://dx.doi.org/10.1155/2020/2508283.

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Background. Rifampicin resistance (RR) is associated with mortality among tuberculosis (TB) patients coinfected with HIV. We compared the prevalence of RR among TB patients with and without HIV coinfection at the National Tuberculosis Treatment Center (NTTC) in Uganda, a TB/HIV high burdened country. We further determined associations of RR among TB/HIV-coinfected patients. Methods. In this secondary analysis, we included adult (≥18 years) bacteriologically confirmed TB patients that were enrolled in a cross-sectional study at the NTTC in Uganda between August 2017 and March 2018. TB, RR, and

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Hayibor, Kenneth Mawuta, Delia Akosua Bandoh, Adwoa Asante-Poku, and Ernest Kenu. "Predictors of Adverse TB Treatment Outcome among TB/HIV Patients Compared with Non-HIV Patients in the Greater Accra Regional Hospital from 2008 to 2016." Tuberculosis Research and Treatment 2020 (August 4, 2020): 1–8. http://dx.doi.org/10.1155/2020/1097581.

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Introduction. The convergence of TB and HIV dual epidemics is a major public health challenge in Ghana as well as many developing countries. Treatment outcome monitoring is a vital part of the surveillance needed to successfully eliminate TB. The impact of HIV status and demographic and treatment-related factors on adverse TB treatment outcome has not been studied in the Greater Accra Regional Hospital. This study determined factors associated with TB treatment outcome in patients with TB-HIV coinfection and TB-only infection in the hospital. Method. A cross-sectional study was carried out in

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Faye, Lindiwe M., Mojisola C. Hosu, Joshua Iruedo, et al. "Treatment Outcomes and Associated Factors among Tuberculosis Patients from Selected Rural Eastern Cape Hospitals: An Ambidirectional Study." Tropical Medicine and Infectious Disease 8, no. 6 (2023): 315. http://dx.doi.org/10.3390/tropicalmed8060315.

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An essential metric for determining the efficacy of tuberculosis (TB) control programs is the evaluation of TB treatment outcomes; this study was conducted to investigate treatment outcomes and associated factors among tuberculosis patients in rural areas of Eastern Cape, South Africa. Assessing treatment outcomes is fundamental to facilitating the End TB Strategy’s set target. Clinic records from 457 patients with DR-TB were examined for data collection while 101 patients were followed up prospectively. Data were analyzed using Stata version 17.0. The odds ratio and 95% confidence interval we

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Bhering, M., R. Duarte, and A. Kritski. "Treatment outcomes and predictive factors for multidrug-resistant TB and HIV coinfection in Rio de Janeiro State, Brazil." International Journal of Tuberculosis and Lung Disease 25, no. 4 (2021): 292–98. http://dx.doi.org/10.5588/ijtld.20.0887.

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BACKGROUND: Brazil ranks 14th worldwide in the number of TB cases and 19th in terms of TB-HIV co-infected cases. This study aims at identifying clinical and demographic factors associated with unsuccessful treatment outcomes (loss to follow-up, treatment failure and death) of HIV-positive patients with multidrug-resistant TB (MDR-TB) in Rio de Janeiro State, Brazil.METHODS: This was a retrospective cohort study of MDR-TB cases notified from 2000 to 2016 in RJ. Cox proportional hazard regression models were used to assess risk factors associated with unsuccessful treatment in HIV-positive patie

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A Zeru, Melkamu. "Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study." African Health Sciences 21, no. 3 (2021): 1003–9. http://dx.doi.org/10.4314/ahs.v21i3.7.

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Background: TB/HIV co-infection is a major public health problem in many parts of the world. But the prevalence of co-infection was varies among countries. This study was designed to assess prevalence of TB/HIV co-infection and to determine its factors. Methods: A retrospective study was done among HIV-positive patients at Hiwot Fana hospital from December, 2014 to 2018. The study participants were selected by simple random sampling. Patients with incomplete chart reviews were exclud- ed and demographic, clinical and laboratory information were analyzed using SPSS and STATA. Uni-vitiate

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Frolova, OP P., VA A. Polesskiy, VA A. Stakhanov, and OV V. Butylchenko. "ACTUAL ISSUES OF PERSONNEL TRAINING ON TUBERCULOSIS ASSOCIATED WITH HIV INFECTION." Science and Innovations in Medicine 2, no. 2 (2017): 66–70. http://dx.doi.org/10.35693/2500-1388-2017-0-2-66-70.

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During the period of registration of tuberculosis associated with HIV infection in Russia (since 1999), its morbidity rate has increased 82.2 times. Changes in pathogenesis of tuberculosis in condition of deep immunodeficiency in patients with HIV infection require improvement of approaches to the training of medical workers who provide anti-tuberculosis care. Aim - improving approaches to personnel training on TB care for people with HIV infection. Methods. Accounting forms 263y-TB "Personal records of patients with TB comorbid with HIV infection" (65,000 records) and reporting forms of Rosst

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Muriuki, Patrick Kiogora, Musa Otieno Ngayo, Moses Njire, et al. "Non-communicable diseases and resistant tuberculosis, a growing burden among people living with HIV in Eastern Kenya." PLOS Global Public Health 5, no. 6 (2025): e0004212. https://doi.org/10.1371/journal.pgph.0004212.

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Human Immunodeficiency Virus (HIV) and tuberculosis (TB) continue to pose a significant health burden in Kenya. Countries with the highest rates of people living with HIV (PLWH) also have a high prevalence of non-communicable diseases (NCDs), including type 2 diabetes (T2D) and hypertension (HPT). This study evaluated the burden and factors associated with T2D, HPT, and TB, including resistant strains among PLWH receiving antiretroviral therapy (ART) in Eastern Kenya. Blood and sputum samples, and baseline information were collected from 280 consenting PLWH. The participants’ blood pressure (B

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Ochonye, Bartholomew, Olaniyi Felix Sanni, Godwin Emmanuel, et al. "A retrospective study of tuberculosis prevalence and associated factors among HIV-positive key populations in Nigeria." PLOS Global Public Health 4, no. 7 (2024): e0003461. http://dx.doi.org/10.1371/journal.pgph.0003461.

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HIV is a major risk factor for active Tuberculosis (TB.) This raises patients’ risk of original infection, reinfection, and TB reactivation. Providing healthcare to KPLHIV in developing countries requires TB prevalence research. This study aims to determine the prevalence of TB and HIV co-infection and associated factors among KPLHIV. This is a retrospective cross-sectional study among KP’s living with HIV enrolled on care in One Stop Shop (OSS) of Heartland Alliance Ltd/GTE across six states in Nigeria. Data were analysed using IBM SPSS version 25.0. Secondary data analysis of client’s record

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Moskaliuk, V. D., and T. R. Kolotylo. "CHARACTERISTICS OF SOME IMMUNOLOGICAL INDICATORS OF HIV INFECTION IN COMBINATION WITH TUBERCULOSIS." Інфекційні хвороби, no. 1 (April 13, 2021): 13–17. http://dx.doi.org/10.11603/1681-2727.2021.1.11947.

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The purpose of the work is to carry out a comparative analysis of epidemiological, clinical and individual laboratory parameters of groups of patients with HIV infection associated with tuberculosis (TB) and TB monoinfection. Patients and methods. A comprehensive immunological examination was performed on 231 patients, including 155 HIV-infected with active newly diagnosed tuberculosis and 76 on tuberculosis alone. The HIV/TB group was divided into 3 subgroups depending on the time of TB accession to HIV infection. The levels of interleukin-4 (IL-4) and interferon-γ (IFN-γ) were compared for g

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Pinsai, Subencha. "1342. Impact of HIV Infection on Treatment Outcome of New Tuberculosis Patients Attending Tuberculosis and Antiretroviral Treatment Services in the Community-Based Hospital, Thailand: A Retrospective Cohort Study." Open Forum Infectious Diseases 6, Supplement_2 (2019): S485—S486. http://dx.doi.org/10.1093/ofid/ofz360.1206.

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Abstract Background Tuberculosis (TB) and HIV are one of the significant public health problems in Thailand, and an estimated 15,000 individuals have a dual infection. Both HIV and TB each disease speeds up the progression of each other. TB is the leading cause of death in HIV-infected individuals, and HIV coinfected TB patients have disease-specific, and treatment affected their treatment outcomes. There is insufficient evidence on issues of TB and HIV co-infection patients received treatment. This study aimed to assess the impact of HIV status on treatment outcome of TB patients. Methods We

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Abdelgawad, Noha, Maxwell Chirehwa, Charlotte Schutz, et al. "Pharmacokinetics of antitubercular drugs in patients hospitalized with HIV-associated tuberculosis: a population modeling analysis." Wellcome Open Research 7 (November 28, 2022): 72. http://dx.doi.org/10.12688/wellcomeopenres.17660.2.

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Background. Early mortality among hospitalized HIV-associated tuberculosis (TB/HIV) patients is high despite treatment. The pharmacokinetics of rifampicin, isoniazid, and pyrazinamide were investigated in hospitalized TB/HIV patients and a cohort of outpatients with TB (with or without HIV) to determine whether drug exposures differed between groups. Methods. Standard first-line TB treatment was given daily as per national guidelines, which consisted of oral 4-drug fixed-dose combination tablets containing 150 mg rifampicin, 75 mg isoniazid, 400 mg pyrazinamide, and 275 mg ethambutol. Plasma s

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Abdelgawad, Noha, Maxwell Chirehwa, Charlotte Schutz, et al. "Pharmacokinetics of antitubercular drugs in patients hospitalized with HIV-associated tuberculosis: a population modeling analysis." Wellcome Open Research 7 (March 1, 2024): 72. http://dx.doi.org/10.12688/wellcomeopenres.17660.3.

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Background Early mortality among hospitalized HIV-associated tuberculosis (TB/HIV) patients is high despite treatment. The pharmacokinetics of rifampicin, isoniazid, and pyrazinamide were investigated in hospitalized TB/HIV patients and a cohort of outpatients with TB (with or without HIV) to determine whether drug exposures differed between groups. Methods Standard first-line TB treatment was given daily as per national guidelines, which consisted of oral 4-drug fixed-dose combination tablets containing 150 mg rifampicin, 75 mg isoniazid, 400 mg pyrazinamide, and 275 mg ethambutol. Plasma sam

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Mirahmadizadeh, Alireza, Mehdi Sharafi, Jafar Hassanzadeh, and Mozhgan Seif. "Prevalence and risk factors associated with tuberculosis and HIV coinfection in Iran: A multivariate firth logistic regression for rare events." Journal of Infection in Developing Countries 17, no. 12 (2023): 1775–81. http://dx.doi.org/10.3855/jidc.17439.

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Introduction: Among the complications caused by HIV infection, tuberculosis (TB) is the most important challenge. The study aimed to determine the predictors of TB and HIV coinfection by using Firth logistic regression analysis. Methodology: This cross-sectional study was conducted on 32,168 HIV-positive patients diagnosed in Iran. The required information was obtained from the national HIV/AIDS surveillance data. Results: The prevalence of TB in HIV patients was 3.2%; the prevalence of TB in males and females was 944 (91.83%) and 84 (8.17%), respectively. Based on results of multivariate Firt

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Zetola, Nicola M., Surbhi Grover, Chawangwa Modongo, et al. "Collision of Three Pandemics: The Coexistence of Cervical Cancer, HIV Infection, and Prior Tuberculosis in the Sub-Saharan Country of Botswana." Journal of Global Oncology 2, no. 1 (2016): 47–50. http://dx.doi.org/10.1200/jgo.2015.001701.

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Cervical cancer is the leading cause of cancer-related mortality in the developing world, where HIV and Mycobacterium tuberculosis (TB) infection are also endemic. HIV infection is independently associated with increased morbidity and mortality among women with cervical cancer. TB is believed to increase the risk of malignancies and could cause chronic inflammation in the gynecologic tract. However, the relationship between cervical cancer and TB in settings hyperendemic for HIV is unknown. We found that 18 (10%) of a cohort of 180 women with cervical cancer in Botswana had a history of TB dis

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