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Journal articles on the topic 'Hl 4343'

Author: Grafiati

Published: 25 July 2024

Last updated: 31 July 2025

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1

Parker, Helen M., Robyn Gallagher, Christine Duffield, Ding Ding, David Sibbritt, and Lin Perry. "Occupational and Leisure-Time Physical Activity Have Different Relationships With Health: A Cross-Sectional Survey Study of Working Nurses." Journal of Physical Activity and Health 18, no. 12 (2021): 1495–502. http://dx.doi.org/10.1123/jpah.2020-0415.

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Background: Recent research has focused on the potential benefits of physical activity in occupational settings in addition to leisure time. However, occupational physical activity (OPA) differs substantially for occupations that require heavy and repetitive physical work, such as nursing. We explored associations between leisure time and OPA and health outcomes in working nurses and midwives. Methods: Nurses who were enrolled in the Fit For the Future study (New South Wales, Australia) and who completed physical activity questionnaires (n = 4343) were classified according to high (HO) or low

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Yawson, Sally Mensa, Kenneth K. K. Baidoo, Alhassan Adam Jangu, Emmanuel D. Kitcher, and Benjamin Abaidoo. "Noise Induced Hearing Loss Among Sawmill Workers in a Sub-Saharan African Country." East African Scholars Journal of Medical Sciences 7, no. 02 (2024): 41–49. http://dx.doi.org/10.36349/easms.2024.v07i02.004.

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Introduction: Noise Induced Hearing Loss (NIHL) is a permanent sensorineural hearing loss (HL) which affects the quality of life of exposed individuals. Aim: To determine the prevalence of NIHL among sawmill workers at the Timber market and petty traders in Accra, Ghana, and to assess the difference in actual and self-reported HL among the sawmill workers. Methods: This was a comparative study of NIHL among sawmill workers at the Agbogbloshie Timber Market of Accra and petty traders whose work environment was situated remotely from the sawmill. Data was analysed using SPSS version 20.0. Demogr

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HIBINO, YUSUKE, KENTA YAMASHITA, YOU SAKURAI, and HSUAN-CHING HO. "Two new species of the snake eel genus Bascanichthys (Anguilliformes: Ophichthidae) from the northwestern Pacific." Zootaxa 5189, no. 1 (2022): 103–13. http://dx.doi.org/10.11646/zootaxa.5189.1.12.

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Two new species of the elongate snake eel genus Bascanichthys are described from the northwestern Pacific. Bascanichthys kabeyawan sp. nov. is described based on a single specimen collected from estuary of southern Taiwan. It is characterized by having head 4.6% TL; tail 52.3% TL; body depth at gill opening 1.1% TL; predorsal-fin length 58.4% HL; snout length 10.9% HL; body bicolored, head without bands; lateral-line pores anterior to anus 104; vertebral formula 4-103-224. Bascanichthys ryukyuensis sp. nov. is described based on two specimens collected from the shallow water of Okinawa-jima Is

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Yu, Myeong Sang, Kwang-Sun Lee, and Jong Woo Chung. "Long-Term Results of Endolymphatic Mastoid Shunt Surgery in Patients with Intractable Ménière's Disease." Otolaryngology–Head and Neck Surgery 141, no. 2 (2009): 237–42. http://dx.doi.org/10.1016/j.otohns.2009.03.014.

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OBJECTIVE: To evaluate changes in vertigo and hearing from patients with Ménière's disease managed by endolymphatic mastoid shunt (EMS). STUDY DESIGN: Case series with chart review. SETTING: Tertiary referral center. SUBJECTS AND METHODS: Data from 16 patients were analyzed using 1995 AAO–HNS criteria. RESULTS: Among 16 patients, six had class A vertigo control two years after treatment, five had class B, one class C, three class D, and one class F. At four years after surgery, seven patients had class A, four class B, three class C, and two class F. The mean functional level before surgery wa

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Antsiferova, A. A., M. V. Lopatina, A. V. Kontsevaya, P. V. Ipatov, and O. M. Drapkina. "Health literacy, including related vaccination, of the working Russian population: data from a survey on the Atria platform." Cardiovascular Therapy and Prevention 23, no. 8 (2024): 4112. http://dx.doi.org/10.15829/1728-8800-2024-4112.

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Health literacy (HL), including related vaccination, is an important health determinant. For the working population, it helps to maintain and improve their ability to work. Despite the clear benefits of vaccination, vaccine confidence has recently declined worldwide, which may lead to decreased vaccination coverage and a renewal of infectious diseases. Based on this, increasing the level of public health, including vaccination issues, is one of the preventive medicine tasks. Staff groups seem to be an effective place for implementing measures to improve the health and vaccination prevention of

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Kanaev, Paul M., Angelina N. Milovanova, and Anastasia I. Andryunina. "Hodgkin Lymphoma in the Republic of Mordovia (2013–2023): Incidence, Mortality, Regional Disparities vs National Trends." Ogarev-online 13, no. 2 (2025): 193–201. https://doi.org/10.15507/2311-2468.013.202502.193-201.

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Introduction. Hodgkin lymphoma (HL) is a malignant neoplasm of the lymphatic system, necessitating investigation into its regional epidemiology and pathohistological characteristics. The aim of the study is to identify the trends in HL incidence and mortality in the Republic of Mordovia for 2013–2023 and to compare these data with nationwide figures for the Russian Federation.Materials and Methods. Research data were obtained from the medical statistics registries of the Republic of Mordovia and the Russian Federation for the period of 2013–2023, supplemented by publications on HL epidemiology

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Nguyen, Minh H., Thu T. M. Pham, Kien T. Nguyen, et al. "Negative Impact of Fear of COVID-19 on Health-Related Quality of Life Was Modified by Health Literacy, eHealth Literacy, and Digital Healthy Diet Literacy: A Multi-Hospital Survey." International Journal of Environmental Research and Public Health 18, no. 9 (2021): 4929. http://dx.doi.org/10.3390/ijerph18094929.

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Background: The COVID-19 pandemic has been disseminating fear in the community, which has affected people’s quality of life, especially those with health problems. Health literacy (HL), eHealth literacy (eHEAL), and digital healthy diet literacy (DDL) may have potential impacts on containing the pandemic and its consequences. This study aimed to examine the association between the fear of COVID-19 scale (FCoV-19S) and the health-related quality of life (HRQoL), and to examine the effect modification by HL, eHEAL, and DDL on this association. Methods: A cross-sectional study was conducted in 11

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Xie, Dongxu, Shuben Li, and Liqin Ren. "Hydrophobic chromatography of the HL-60 cellular fraction co-binding with hexamethylene bisacetamide." Journal of Chromatography B: Biomedical Sciences and Applications 688, no. 2 (1997): 359–63. http://dx.doi.org/10.1016/s0378-4347(96)00312-x.

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Kharuzhyk, S. A., E. A. Zhavrid, and N. U. Sachivko. "Diagnostic Effectiveness of whole Body Diffusion- Weighted Magnetic Resonance Imaging in Focal and Diffuse Bone Marrow Involvement in Patients with Lymphoma." Medical Visualization, no. 5 (October 28, 2017): 66–81. http://dx.doi.org/10.24835/1607-0763-2017-5-66-81.

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Objective:to compare diagnostic effectiveness of whole body diffusion-weighted imaging (DWI), other magnetic resonance imaging (MRI) pulse sequences and iliac wing trephine biopsy in the diagnosis of focal and diffuse bone marrow (BM) involvement in patients with lymphoma.Materials and methods.Prospective study included 130 patients with lymphoma who underwent whole-body MRI-DWI and iliac wing trephine biopsy before treatment (64 (49,2%) men, 66 (50,8%) women, middle age 43,3 ± 16,3 years, interval of 18–79 years). Hodgkin's lymphoma (HL) was at 57 (44%) patients, non-Hodgkin lymphomas (NHL) –

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10

Johnson, Connie N., Paul R. Fisher, Jinsheng Huang, Richard P. Vetanovetz, and William R. Argo. "Quantifying the Acidity of an Ammonium-based Fertilizer in Containerized Plant Production." HortScience 45, no. 7 (2010): 1099–105. http://dx.doi.org/10.21273/hortsci.45.7.1099.

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In current horticultural practice, potential acidity or basicity of fertilizers is estimated using Pierre's method (PM) expressed in calcium carbonate equivalents (CCE) per unit weight of fertilizer. PM was developed using mineral field soil systems and may be inaccurate for quantifying fertilizer acidity in containerized plant production given the widespread use of soilless substrates and fertigation. The PM-predicted acidity of an ammonium-based fertilizer was compared against experimental data obtained when ‘Ringo’ geraniums [Pelargonium ×hortorum (Bailey. L.H.)] and ‘Super Elfin’ impatiens

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11

Ortega, Claudia, Yael Eshet, Anca Prica, et al. "Combination of FDG PET/CT Radiomics and Clinical Parameters for Outcome Prediction in Patients with Hodgkin’s Lymphoma." Cancers 15, no. 7 (2023): 2056. http://dx.doi.org/10.3390/cancers15072056.

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Purpose: The aim of the study is to evaluate the prognostic value of a joint evaluation of PET and CT radiomics combined with standard clinical parameters in patients with HL. Methods: Overall, 88 patients (42 female and 46 male) with a median age of 43.3 (range 21–85 years) were included. Textural analysis of the PET/CT images was performed using freely available software (LIFE X). 65 radiomic features (RF) were evaluated. Univariate and multivariate models were used to determine the value of clinical characteristics and FDG PET/CT radiomics in outcome prediction. In addition, a binary logist

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Sieniawski, Michal, Andreas Josting, Carmen Canals, et al. "Late Events in Patients with Relapsed or Refractory Hodgkin’s Lymphoma Treated with an Autologous Stem Cell Transplantation." Blood 110, no. 11 (2007): 834. http://dx.doi.org/10.1182/blood.v110.11.834.834.

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Abstract Background: Autologous stem cell transplantation (ASCT) has been used as a standard treatment in the management of patients (pts) with relapsed/refractory Hodgkin’s lymphoma (HL) in the last few decades. Long-term side effects of this treatment such as secondary malignancies (SM), organ failure and infertility attract scientific interest. Very little data is available on late events among pts with HL treated with ASCT. Material and Methods: We retrospectively analysed HL pts treated with an ASCT and registered in the European Group for Blood and Marrow Transplantation (EBMT) Database.

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Ajayi, B. A., H. A. Agbaje, K. F. Akinsola, F. Oyehan, and S. A. Olayiwola. "Comparative study of morphological traits of adult male and female West African Dwarf goats." Ghanaian Journal of Animal Science 15, no. 1 (2024): 18–24. https://doi.org/10.4314/gjansci.v15i1.2.

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Linear body measurements and live body weights were taken on two hundred (200) adult West African Dwarf (WAD) goats comprising of 115 does and 85 bucks from keeper’s backyard in some selected communities (Iwata, Isundunrin and Ola) in Ejigbo Local Government Area of Osun State. The objectives of the study were to compare the morphological traits between sexes and describe the body morphology of adult WAD goats using a multivariate approach. Variables measured included: Body weight (BW), Face length (FL), Ear width (EW), Ear length (EL), Horn length (HL), Neck length (NL), Neck circumference (N

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14

Yamaguchi, Jun-ichi, Kenji Hachiuma, Yoshitada Kimura, Naoyoshi Ogawa, and Shohei Higuchi. "Highly sensitive determination of TS-962 (HL-004), a novel acyl-CoA:cholesterol acyltransferase inhibitor, in rat and rabbit plasma by liquid chromatography and atmospheric pressure chemical ionization-tandem mass spectrometry combined with a column-switching technique." Journal of Chromatography B: Biomedical Sciences and Applications 750, no. 1 (2001): 99–108. http://dx.doi.org/10.1016/s0378-4347(00)00437-0.

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Genadieva Stavrik, Sonja G., Ariane Boumendil, Kirsty Thomson, et al. "Myeloablative Versus Reduced Intensity Allogeneic Stem Cell Transplantation in Relapsed Hodgkin’s Lymphoma in Recent Years. a Retrospective Analysis of the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation." Blood 124, no. 21 (2014): 2562. http://dx.doi.org/10.1182/blood.v124.21.2562.2562.

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Abstract Introduction. Allogeneic stem cell transplantation (allo-SCT) is a well established therapeutic alternative for those patients with refractory Hodgkin’s lymphoma (HL) who relapse after an autologous stem cell transplantation (ASCT), have chemosensitive disease and a HLA compatible donor available. The impact of the intensity of the conditioning regimen in the outcome of this procedure is still not well understood. An initial retrospective analysis from the European Group for Blood and Marrow Transplantation (EBMT) Lymphoma Working Party (LWP) (Sureda et al, JCO 2010) that compared mye

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16

Hannula, Samuli, Risto Bloigu, Kari Majamaa, Martti Sorri, and Elina Mäki-Torkko. "Self-Reported Hearing Problems among Older Adults: Prevalence and Comparison to Measured Hearing Impairment." Journal of the American Academy of Audiology 22, no. 08 (2011): 550–59. http://dx.doi.org/10.3766/jaaa.22.8.7.

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Background: There are not many population-based epidemiological studies on the association between self-reported hearing problems and measured hearing thresholds in older adults. Previous studies have shown that the relationship between self-reported hearing difficulties and measured hearing thresholds is unclear and, according to our knowledge, there are no previous population-based studies reporting hearing thresholds among subjects with hyperacusis. Purpose: The aim was to investigate the prevalence of self-reported hearing problems, that is, hearing difficulties, difficulties in following

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17

Berlier, Willy, Mohamed El Hamri, Karine Aguera, et al. "Blast Asparagine Synthetase Deficiency in Acute Myeloid Leukemia." Blood 120, no. 21 (2012): 4333. http://dx.doi.org/10.1182/blood.v120.21.4333.4333.

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Abstract Abstract 4333 Introduction L-asparaginase (L-Aspa) is one of the standard components of acute lymphoid leukemia (ALL) therapy. Its efficacy as an antineoplasic agent is due to its capacity to deplete plasmatic asparagine, starving the leukemic cells and subsequently inhibiting protein synthesis. In vitro studies have already shown the sensitivity to L-Aspa of leukemic cells from patients with acute myeloid leukemia (AML), depending on the French-American-British (FAB) subtype (Zwaan et al., 2000; Okada et al., 2003). Despite promising results in clinical trials (Capizzi et al., 1988;

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Bergantim, Rui, Eliana Aguiar, Teresa Garrido, et al. "Poor Stem Cell Mobilization: incidence and Risk Factors." Blood 122, no. 21 (2013): 5439. http://dx.doi.org/10.1182/blood.v122.21.5439.5439.

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Abstract Background and Aims High dose chemotherapy followed by autologous stem cell transplant (ASCT) is an effective treatment for many patients with haematological malignancies. Adequate stem cell mobilization (SCM) and collection are essential for a successful ASCT. Unfortunately, a small group of patients fail to mobilize sufficient stem cell for transplant. In order to explore factors influencing SCM we conducted a retrospective analysis on a large series of candidates for ASCT in a Portuguese transplantation center. Patients and Methods We analyzed 233 patients who underwent consecutive

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Szmyd, Bartosz, Kamila Wypyszczak, Karolina Miarka-Walczyk, et al. "Rare Candidate Variants for Germline Predisposition to Childhood Lymphomas: Go Beyond Aberrations in DNA Repair Genes." Blood 144, Supplement 1 (2024): 1587. https://doi.org/10.1182/blood-2024-208071.

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Introduction : Approximately 10% of pediatric patients with malignancies carry germline predisposing variants. Regarding pediatric patients who developed lymphoma, the pathogenic abnormalities frequently affect DNA repair genes. Identifying these aberrations may contribute to tailored clinical management, appropriate screening protocols, management of comorbidities, and genetic counseling. Therefore, we aimed to identify genetic predispositions to pediatric lymphoma based on familial history and phenotypical features. Methods: We obtained clinical information about 75 patients diagnosed with l

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Mirabilii, Simone, Maria Rosaria Ricciardi, Matteo Allegretti, et al. "Targeting Metabolic Pathways for Leukemia Treatment." Blood 120, no. 21 (2012): 1371. http://dx.doi.org/10.1182/blood.v120.21.1371.1371.

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Abstract Abstract 1371 Aberrant signal transduction pathways influence metabolic changes in neoplastic cells. It is well established, in fact, that cancer cells are characterized by a pro-glycolytic metabolic phenotype and recent evidences confirmed that also leukemia cells may switch to a non-oxidative metabolism. Among the different substrates used to sustain the anabolic processes and to keep the tricarboxylic acid cycle (TCA) active, the fatty acid oxidation (FAO) may represent an alternative carbon source. The carnitine palmitoyl transferase 1a (CPT1a) catalyzes the first step of FAO, by

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Hoebarth, Gerald, Susan Kubik, Martin Wolfsegger, et al. "Pharmacokinetics of Baxter’s Longer Acting rFVIII (BAX 855) in Factor VIII Ko Mice, Rats and Cynomolgus Monkeys." Blood 118, no. 21 (2011): 4346. http://dx.doi.org/10.1182/blood.v118.21.4346.4346.

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Abstract Abstract 4346 The pharmacokinetic profile of BAX 855, a longer acting PEGylated variant of Baxter’s recombinant FVIII based on the ADVATE™ manufacturing process, was assessed in comparison to ADVATE™ after a single intravenous bolus injection at a target dose of 200 IU/kg BW in mice and rats and 350 IU/kg BW in cynomolgus monkeys. Mean residence time (MRT), terminal half-life (HL), total clearance standardized per kg body mass (Cl), the AUC0-tlast (the area under the concentration vs. time curve from 0 to the last measured time point), the in vivo recovery (IVR) and volume of distribu

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Cho, Eunpi, Hyam I. Levitsky, Jeanne Kowalski, et al. "K562/GM-CSF Immunotherapy as a “Booster” Vaccine In Chronic Myeloid Leukemia." Blood 116, no. 21 (2010): 4347. http://dx.doi.org/10.1182/blood.v116.21.4347.4347.

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Abstract Abstract 4347 Background: Chronic myeloid leukemia (CML) is a disease that is responsive to T-cell-mediated immunity. K562/granulocyte macrophage-colony stimulating factor (GM-CSF) is a vaccine derived from a CML cell line that produces GM-CSF and expresses several CML-associated antigens. An initial pilot study was performed in 19 patients in chronic phase CML who had achieved at least a major cytogenetic response on imatinib mesylate (IM) but had measurable molecular disease. The results suggested that immunotherapy resulted in a lowering tumor burden in the majority of patients (n

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Koczian, Fabian, Jan Vomacka, Binje Vick, et al. "Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells Towards Cytostatics." Blood 128, no. 22 (2016): 2319. http://dx.doi.org/10.1182/blood.v128.22.2319.2319.

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Abstract Background Combination therapy has proved to be a successful strategy and generally benefits from the crosstalk of antileukemic agents. However, the mechanisms of amplification remain mostly elusive and the outcome of relapsed or chemoresistant ALL and AML is still dismal. Therefore, drug discovery is not only challenged to address the identification of novel compounds and targets, but also to enhance the understanding of their molecular interaction pathways in order to exploit their potential for the translation into combination therapies. Screening small molecules that sensitize can

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Bartlett, Nancy L., David J. Straus, Monika Dlugosz-Danecka, et al. "Brentuximab Vedotin with Chemotherapy for Stage 3/4 Classical Hodgkin Lymphoma (cHL): 4-Year Update of the Echelon-1 Study." Blood 134, Supplement_1 (2019): 4026. http://dx.doi.org/10.1182/blood-2019-124116.

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Introduction: As previously reported, the combination of brentuximab vedotin with doxorubicin, vinblastine and dacarbazine (A+AVD) demonstrated a statistically significant improvement in modified progression free survival (modified PFS) compared with doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD) in patients with newly diagnosed Stage III or IV classical HL in the phase 3 ECHELON-1 trial (NCT01712490). The benefit of A+AVD in the ITT population observed in the primary analysis was maintained at 3-years median follow-up [3-year PFS: A+AVD: 83.1% (79.9-85.9), ABVD: 76% (72.4-79.2)] a

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Moskowitz, Craig H., Pier Luigi Zinzani, Michelle A. Fanale, et al. "Pembrolizumab in Relapsed/Refractory Classical Hodgkin Lymphoma: Primary End Point Analysis of the Phase 2 Keynote-087 Study." Blood 128, no. 22 (2016): 1107. http://dx.doi.org/10.1182/blood.v128.22.1107.1107.

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Abstract Background: Classical Hodgkin lymphoma (cHL) is characterized by chromosome 9p24.1 alterations (including amplification), leading to overexpression of the PD-L1 and PD-L2 immune checkpoint ligands. This genetically determined dependence on the PD-1 pathway makes cHL an attractive target for PD-1 blockade with the anti-PD-1 monoclonal antibody, pembrolizumab. In the phase 1b KEYNOTE-013 study, pembrolizumab demonstrated high antitumor activity (objective response rate [ORR] of 65%) in heavily pretreated patients with cHL. KEYNOTE-087 is a phase 2 study designed to further evaluate the

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Giertz, Mia, Henri Aarnivala, Sascha Wilk Michelsen, et al. "Symptomatic osteonecrosis in children treated for Hodgkin lymphoma: A population‐based study in Sweden, Finland, and Denmark." Pediatric Blood & Cancer, August 14, 2024. http://dx.doi.org/10.1002/pbc.31250.

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AbstractBackgroundOsteonecrosis (ON) is a potentially disabling skeletal complication of cancer treatment. Although symptomatic osteonecrosis (sON) is well‐known in acute lymphoblastic leukemia (ALL), with an incidence around 6%, studies on sON in pediatric Hodgkin lymphoma (HL) are scarce. The aim of this study was to examine the incidence, risk factors, and outcome of sON in children treated for HL.ProcedureA total of 490 children under 18, diagnosed with HL between 2005 and 2019 in Sweden, Finland, and Denmark were eligible for the study. Data on patient characteristics, HL treatment, and d

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Mehta, Mansi, Bolivia Crocete Aloysia Fernandes, and Jaison Lawrence Alexander Santhi. "Predicting the future: Socio-economic trends in Hodgkin versus non-Hodgkin lymphoma survival outcomes." Journal of Clinical Oncology 43, no. 16_suppl (2025). https://doi.org/10.1200/jco.2025.43.16_suppl.e19036.

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e19036 Background: Lymphoma, categorized into Hodgkin (HL) and Non-Hodgkin (NHL), is the most common hematological malignancy worldwide. NHL is the eighth most common malignancy in the US and accounts for 3.3% of all cancer related deaths. HL is a relatively rare entity with 88.9% 5-Year Relative Survival Rate in the US. Socio-demographic factors play a pivotal role in the incidence and survival outcomes. This study aims to compare the evolving epidemiological landscape of HL versus NHL in different socio-demographic groups. Methods: Incidence and mortality data for HL and NHL across 185 count

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Yukio, Hitotsuyanagi, Taka-aki Hinosawa, Yoshie Nakagawa, Sho Ito, Ji-Ean Lee, and Tomoyo Hasuda. "Bridged peptide analog of RA-VII, an antitumor bicyclic hexapeptide." Synlett, October 13, 2022. http://dx.doi.org/10.1055/a-1960-4340.

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A bridged peptide analog of RA-VII was designed, in which the α carbons of residues 1 and 4 were linked by a tetramethylene chain to restrict the conformational freedom of the backbone of the 18-membered cyclopeptide. This peptide analog was synthesized by a ring-closing metathesis reaction of [L-2-allylglycine-1, L-2-allylglycine-4]RA-VII and a subsequent hydrogenation of the resulting olefinic compound. Compared with RA-VII, the analog showed much weaker cytotoxic activity toward human promyelocytic leukemia HL-60 cells and human colon carcinoma HCT-116 cells, which may be accounted for by t

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Mori, Takahisa, Kazuhiro Yoshioka, and Yuhei Tanno. "Abstract TP8: Sodium-glucose Cotransporter 2 Inhibitors Coupled With 40% Carbohydrate Diet Improve Hyperglycemia Safely And Soon In An Acute Stroke Stage." Stroke 53, Suppl_1 (2022). http://dx.doi.org/10.1161/str.53.suppl_1.tp8.

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Introduction: Hyperglycemia must be improved in acute stroke patients. However, effective treatment has not been established. Hypothesis: Moderate-carbohydrate (carbo) diet and sodium-glucose cotransporter 2 (SGLT2) inhibitors can lower blood glucose level (BGL) safely and soon in patients with oral ingestion and normal renal function. Methods: For the retrospective observational study, we included patients who 1) were admitted within 24 h of stroke onset between Jan 2011 and March 2019, 2) had not undergone insulin therapy, 3) presented hemoglobin A1c ≥ 6.5%, BGL ≥ 11.1 mmol/L, and estimated

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