Relevant bibliographies by topics / HLSS

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'HLSS'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "HLSS"

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Sun, Fangfang, Qing Zheng, Hualin Fan, and Daining Fang. "The Mechanical Properties of Hierarchical Truss-Walled Lattice Materials." International Journal of Applied Mechanics 09, no. 02 (March 2017): 1750027. http://dx.doi.org/10.1142/s1758825117500272.

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To construct a hierarchical lattice structure (HLS), truss wall is introduced into ordinary lattice structure (OLS). Young’s modulus, yield strength and buckling stress of HLSs were evaluated theoretically. Failure maps of different HLSs were plotted and compared based on the theoretical analyses. It is indicated that mechanical behaviors of hexagonal HLSs made of triangular lattice walls can be greatly enhanced by the hierarchical wall structure, while properties of triangular HLSs are weakened, except the anti-buckling resistance. When HLSs are made of bending-dominated honeycomb walls, their properties will be reduced, indicating that hierarchical structure should be appropriately designed to make ultra-light structures benefit from this construction. This viewpoint is strengthened by the discussions on the performances of high order lattice structures, where only bending-dominated HLSs with stretching-dominated lattice wall benefit from the hierarchy.
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Unger, J. K., G. Catapano, N. A. Horn, A. Schroers, J. C. Gerlach, and R. Rossaint. "Comparative Analysis of Metabolism of Medium-and Plasma Perfused Primary Pig Hepatocytes Cultured around a 3-D Membrane Network." International Journal of Artificial Organs 23, no. 2 (February 2000): 104–10. http://dx.doi.org/10.1177/039139880002300207.

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Culture media are frequently used in the evaluation of metabolical functions of hepatocytes in hybrid liver support systems (hLSS). However, media compositions differ substantially from those of plasma. Therefore, our study was designed to investigate whether current in vitro studies with medium are suitable to assess the metabolical competence of hLSS-cultures during clinical application as well as to explore whether the cell nutrition with medium provides a suitable modus operandi for stand by cultivation. Paired bioreactor cultures were perfused with either Williams’ Medium E (MPB) or human plasma (PPB). About 6x108 primary pig hepatocytes (>97% viability) were cultured in three laboratory scale bioreactors designed according to Gerlach's bioreactor-concept. Different perfusion protocols were initiated after a standardised period allowing for cell attachment and reorganisation in aggregates. Whereas patterns of enzyme release were similar in both protocols the metabolical behaviour was different between MPB (anabolic state) and PPB (catabolic state). Furthermore, compared to MPB the lidocaine-MEGX-tests for PPB demonstrated lower MEGX-concentrations and a different reaction pattern. We conclude that the nutrition of hepatocytes with medium during the stand by period itself might influence the cell function and subsequently the efficacy of the hLSS-treatment during clinical application. (Int J Artif Organs 2000; 23: 104–10)
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Gavriilidou, Zoe, and Lydia Mitits. "The Socio-linguistic Profiles, Identities, and Educational Needs of Greek Heritage Language Speakers in Chicago." Journal of Language and Education, no. 1 (March 31, 2021): 80–97. http://dx.doi.org/10.17323/jle.2021.11959.

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The present study aims to further the research on heritage language speakers (HLSs) by providing the socio-linguistic profiles and identities of an uninvestigated community of heritage speakers, namely the Greeks of Chicago, thus offering data for a less-studied HL, Greek. The participants were fifty-four (N=54) first, second, and third-generation Greek HLSs. The socio-linguistic data were collected through an online survey, while identification with Greek culture as well as ethnic attachment and practice of Greek traditions were investigated through the content analysis of data from the Greek Heritage Language Corpus. The results of the study are discussed with respect to how they can improve our knowledge of the educational needs of Greek HL learners. This research-based knowledge can be employed for addressing the academic needs of HL learners through educational programs. The authors propose an agenda for a more linguistically and culturally responsive education program for HL learners, in general, and Greek HL learners in diasporic communities, in particular.
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Zhai, Zhongxu, Yun Wang, Andrew Benson, Chia-Hsun Chuang, and Gustavo Yepes. "Linear bias and halo occupation distribution of emission-line galaxies from Nancy Grace Roman Space Telescope." Monthly Notices of the Royal Astronomical Society 505, no. 2 (May 27, 2021): 2784–800. http://dx.doi.org/10.1093/mnras/stab1539.

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ABSTRACT We present measurements of the linear galaxy bias of Hα and [O iii] emission-line galaxies (ELGs) for the High Latitude Spectroscopic Survey (HLSS) of Nancy Grace Roman Space Telescope (or Roman), using galaxy mocks constructed using semi-analytical model for galaxy formation, Galacticus, with a large cosmic volume and redshift coverage. We compute the two-point statistics of galaxies in configuration space and measure linear bias within scales of 10–50 h−1 Mpc. We adopt different selection algorithms to investigate the impact of the Roman line flux cut, as well as the effect of dust model used to calibrate Galacticus, on the bias measurements. We consider galaxies with Hα and [O iii] emissions over the redshift range 1 < z < 3, as specified by the current baseline for the Roman HLSS. We find that the linear bias for the Hα and [O iii] ELGs can be expressed as a linear function with respect to redshift: b ≃ 0.9z + 0.5 for H$\alpha \, (1\lt z\lt 2)$, and b ≃ z + 0.5 for [O iii] (2 < z < 3). We have also measured the halo occupation distributions of these Hα and [O iii] ELGs to understand their distribution within dark matter haloes. Our results provide key input to enable the reliable forecast of dark energy and cosmology constraints from Roman.
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Endersby, Raelene, Ian J. Majewski, Louise Winteringham, Jennifer G. Beaumont, Amy Samuels, Robin Scaife, Esther Lim, Merlin Crossley, S. Peter Klinken, and Jean-Philippe Lalonde. "Hls5 regulated erythroid differentiation by modulating GATA-1 activity." Blood 111, no. 4 (February 15, 2008): 1946–50. http://dx.doi.org/10.1182/blood-2007-04-085746.

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Hemopoietic lineage switch (Hls) 5 and 7 were originally isolated as genes up-regulated during an erythroid-to-myeloid lineage switch. We have shown previously that Hls7/Mlf1 imposes a monoblastoid phenotype on erythroleukemic cells. Here we show that Hls5 impedes erythroid maturation by restricting proliferation and inhibiting hemoglobin synthesis; however, Hls5 does not influence the morphology of erythroid cells. Under the influence of GATA-1, Hls5 relocates from cytoplasmic granules to the nucleus where it associates with both FOG-1 and GATA-1. In the nucleus, Hls5 is able to suppress GATA-1–mediated transactivation and reduce GATA-1 binding to DNA. We conclude that Hls5 and Hls7/Mlf1 act cooperatively to induce biochemical and phenotypic changes associated with erythroid/myeloid lineage switching.
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Bruno, Stefania, Maria Beatriz Herrera Sanchez, Chiara Pasquino, Marta Tapparo, Massimo Cedrino, Ciro Tetta, and Giovanni Camussi. "Human Liver-Derived Stem Cells Improve Fibrosis and Inflammation Associated with Nonalcoholic Steatohepatitis." Stem Cells International 2019 (June 2, 2019): 1–14. http://dx.doi.org/10.1155/2019/6351091.

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Cell therapy may be regarded as a feasible alternative to whole organ transplantation to treat end-stage liver diseases. Human liver stem cells (HLSCs) are a population of cells easily obtainable and expandable from a human adult liver biopsy. HLSCs share with mesenchymal stromal cells the same phenotype, gene expression profile, and differentiation capabilities. In addition, HLSCs show a specific commitment to the hepatic phenotype. Injection of HLSCs into immunodeficient mice fed with a methionine-choline-deficient diet to induce nonalcoholic steatohepatitis ameliorates liver function and morphology. In particular, HLSC treatment induced a reduction of liver fibrosis and inflammation at morphological and molecular levels. Moreover, HLSCs were able to persist for up to 3 weeks after the injection. In conclusion, HLSCs have healing effects in a model of chronic liver disease.
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Uk Son, Seong, Soojin Jang, Yuna Choi, Mirae Park, Hye Young Son, Yong-Min Huh, Soo-Jin Yeom, et al. "Distinctive Nanogels as High-Efficiency Transdermal Carriers for Skin Wound Healing." Journal of Biomedical Nanotechnology 16, no. 3 (March 1, 2020): 304–14. http://dx.doi.org/10.1166/jbn.2020.2893.

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We propose that nanogels (HLGs) prepared by simply blending an epidermal growth factor (EGF)-loaded hyaluronan (HA)-based nanoformulation and poloxamers can be efficient transdermal drug carriers. In particular, due to the thermogelling behavior of poloxamer, when the HLGs, which are liquid at room temperature, are applied to the skin's surface, they form a gel at skin temperature. First, lipid-based nanoformulations (EGF-LNs) were fabricated by the lipid thin film method and then chemically conjugated with HA on the surface of the films to prepare EGF-loaded HA-based nanoformulations (EGF-HLNs). Both EGF-LNs and EGF-HLNs exhibited a uniform size and spherical lamellar structure. The EGF-HLN was added to a poloxamer solution to form EGF-HLG, which is a liquid at room temperature and a gel at skin temperature. HLGs have been shown to be able to deliver and permeate EGF well into the skin using both in vitro and in vivo systems, thus serving as an effective transdermal delivery system. In addition, it has been confirmed that this system could be a possible implantable drug carrier. Therefore, HLGs, which are uncomplicated and easily prepared, are expected to be easily used not only in the pharmaceutical field but also in the cosmetic field.
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Catapano, G., and L. De Bartolo. "Importance of the Kinetic Characterization of Liver Cell Metabolic Reactions to the Design of Hybrid Liver Support Devices." International Journal of Artificial Organs 19, no. 11 (November 1996): 670–76. http://dx.doi.org/10.1177/039139889601901108.

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Hybrid liver support devices (HLSDs) developed for the treatment of fulminant hepatic failure often perform well on a laboratory scale but rapidly lose their metabolic functions, or are not therapeutically effective, on a clinical scale. This suggests that the procedures adopted so far for the design of HLSDs are susceptible to improvement. In this paper, we discuss how essential a reliable and thorough kinetic characterization of the liver cell metabolic reactions is to the design of a clinically effective membrane HLSD. The features of the bioreactors used for the kinetic characterization of liver cell reactions are presented and discussed on the basis of the multifactorial nature of such reactions. The relevance of kinetics to the design of a membrane HLSD is also discussed with respect to the effect of the kinetics of oxygen consumption on the performance of the device.
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Kalam, Rehna, Ciza Thomas, and M. Abdul Rahiman. "Detection of Brain Tumor in MRI Images Using Optimized ANFIS Classifier." International Journal of Uncertainty, Fuzziness and Knowledge-Based Systems 29, Supp01 (March 26, 2021): 1–29. http://dx.doi.org/10.1142/s0218488521400018.

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Tumor is basically a most common disease of brain and the Brain Tumor (BT) treatment has crucial significance. A diagnostic procedure called MRI image that is employed for detecting BT. It is the utmost important and intricate tasks in numerous medical-image applications since it typically involves a huge quantity of data. A lot of methods were applied in BT detection ranging as of image processing to examine the BT; however, the prevailing BT technique is tedious and less effective. So, this paper proposed the detection of the BT in MRI images utilizing optimized ANFIS classifier. Originally, the input MR image is preprocessed utilizing Gaussian Filter (GF) that removes the noise from the inputted image, additionally, the non-brain tissues (NBT) are removed using the technique of skull stripping (SS). After that, segmentation is performed wherein the tumor part is segmented utilizing CBAC technique and edema part is segmented utilizing HLSS segmentation technique. Then, GLCM in addition to GLRLM features are extracted afterward that extorted features is chosen by BFO algorithm. Finally, the selected features inputted to the optimized ANFIS classifier that classifies the tumor class types as Meningioma, Glioma, along with Pituitary. In ANFIS, the optimization procedure is achieved utilizing the PSO. The proposed system’s performance is contrasted to the prevailing systems regarding precision, recall, specificity, sensitivity, accuracy, together with F-Measure.
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Winteringham, Louise N., Raelene Endersby, Ian J. Majewski, Jennifer Beaumont, Simon Kobelke, Jean-Philippe Lalonde, and Svend Peter Klinken. "Genes Identified in a Hemopoietic Lineage Switch Influence Transcription." Blood 110, no. 11 (November 16, 2007): 1250. http://dx.doi.org/10.1182/blood.v110.11.1250.1250.

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Abstract The J2E erythroblastoid cell line responds to erythropoietin (Epo) by morphological maturation and hemoglobin synthesis. However, on rare occasions, these cells have undergone a spontaneous lineage switch and display features of monoblastoid cells which do not respond to Epo. Amongst the genes up-regulated in the monoblastoid variants were Hemopoietic lineage switch (Hls) 5 and 7. Hls5 is a recently identified member of the RING finger, B Box, Coiled coil (RBCC) or tripartite motif (TRIM) family, which includes PML, a gene involved in acute promyelocytic leukaemia. Hls7 is the murine orthologue of Myeloid leukaemia factor 1 (Mlf1), a gene involved in a t(3;5), associated with acute myeloid leukaemia. We have shown previously that Hls7/Mlf1 imposes a dramatic phenotypic change upon the erythroid cells, rendering them monoblastoid (Williams, J. et al EMBO 1999). We have studied the role of Hls5 and Mlf1 in erythroid commitment and differentiation. Ectopic expression of Hls5 inhibits globin production in erythroid cells and suppresses development of B-FUE and C-FUE. A yeast-two-hybrid screen identified FOG-1 as a binding partner of Hls5. Significantly, FOG-1 is a transcriptional co-regulator of GATA-1, which controls globin gene expression. While Hls5 is able to enhance the repression of GATA-1 activity imposed by FOG-1, it is also able to repress GATA-1 transcriptional activity in the absence of FOG-1. Using electrophoretic mobility shift assay we have shown that Hls5 is able to reduce GATA-1 binding to DNA in a dose dependant manner. This observation that Hls5 reduces GATA-1 binding to promoter elements is mirrored by chromatin immunoprecipitation assays. Expression of MLF1 is highest in CD34+ cells, but is markedly down regulated during erythroid differentiation. Microarray analysis identified a number of known transcriptional regulators differentially expressed in the presence of Mlf1 including ets1, Myc intron binding protein and Tbr2. Mlf1 is able to bind DNA and luciferase reporter assays demonstrated that Mlf1 is able to affect transcription. In addition, Mlf1 interacts with a novel member of the hnRNP family viz Mlf1 associated nuclear protein (Manp). Manp binds to DNA, is able to influence the subcellular localisation of Mlf1 by translocating Mlf1 from the cytoplasm to the nucleus. Importantly, Manp also has an affect on transcription. These data demonstrate that both Hls5 and Mlf1 affect transcription of genes associated with erythroid differentiation.
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Dissertations / Theses on the topic "HLSS"

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Wimmerová, Hana. "Pohyb a hlas." Master's thesis, Akademie múzických umění v Praze.Hudební a taneční fakulta. Knihovna, 2012. http://www.nusl.cz/ntk/nusl-177794.

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The subject of my master thesis is searching for overlaps of both dancing and drama where the means of artistic expression in terms of the performer?s integrity play the key role. The aim is to find and define the crucial points in the art evolution which have been further developed by artists in both drama and dancing. The aim is also to point out the overlapping of genres which either adopted or integrated features of other artistic fields. This master thesis is a follow-up of my bachelor thesis with the main subject being ?movement and voice?. The aim is to pick up the threads of my bachelor thesis dealing with the integration of voice in the contemporary dance and its detailed specification. The source of information are not only the post-modern as well as contemporary artists, but also looking back in the history of modern dance evolution. Vital part of my thesis is a description of my pedagogical experience at the Janáček Conservatory in Ostrava which summarizes my knowledge acquired during the lessons of Modern dance and Dancing Education.
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Sovová, Pavla. "Hlas jako psychosomatická disciplína." Doctoral thesis, Akademie múzických umění v Praze. Divadelní fakulta AMU. Knihovna, 2009. http://www.nusl.cz/ntk/nusl-78208.

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Keywords:Dramatic culture, psychosomatic disciplines, vocal pedagogy, psychosomatic approach of vocal education, qualitative research, introspective observation, case study, skeleton analysis, pedagogical competences, vocal grounding of pedagogues The author places the vocal study to wide context of dramatic culture education. In this context she recapitulates her personal experiences of this kind of education, she points out the benefit of this study for the development of pedagogical competences. The work mainly presents the psychosomatic approach of vocal education whose guarantor and creator, in the Department of Authorship and Pedagogy at the Theatre Faculty of Performing Arts in Prague (KATaP DAMU), is college lecturer Libuše Válková. The principles of psychosomatic approach to the vocal development were used and approved by the author within her education activities for Czech Orff Associaton (Česká Orffova společnost) and at St. John´s College ? Teacher Training College (Svatojánská kolej VOŠPg). The vocal pedagogical process is monitored on the basis of reflections - introspective observation. The statements written by students of the Department of Authoship and Pedagogy and St. John´s College deepen our understanding of the vocal education process. This point of view is ensembled by the case study of a teacher who, thanks to professional lead, succesfully solves her vocal problems (The study contains DVD exemplification of the vocal education lesson.) The mentioned knowledge and experiences are the base for conceiving of new subjects - Vocal and Speech Education and Vocal Grounding - which are placed in undergraduate teachers? training
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Jelínková, Olga. "Bohuslav Martinů: Hlas lesa." Master's thesis, Akademie múzických umění v Praze. Hudební fakulta AMU. Knihovna, 2009. http://www.nusl.cz/ntk/nusl-79115.

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In 2009 we hold anniversaries for many composers, for example G.F.Händel, Henry Purcell, J.Haydn and Felix Mandelssohn-Bartholdy. In this abundance of celebrations we should not overlook the 50th anniversaryof Bohuslav Martinů´s death. Czech composer B. Martinů ( 1890 - 1959) was one of the most prolific composers of the 20th century. He was born and grew up in Polička . In 1923 he left his country of birth to study with Albert Roussel in Paris, where he lived for the next 17 years. In 1941 he emigrated to the States, fleeing the German invasion of France. He wrote for leading American orchestras in the following decade. He became homesick bud he never returned to his homeland. Martinů spent his later years in Switzerlandand and he died at age of 69 in Liestal. He wrote almost 400 pieces ( symphonies, operas, ballet and a large number of orchestral, chamber, vocal and vocal- instrumental works). His Epic of Gilgamesh, Field Mass, The Opening of the Wells, and his operas Julietta and The Greek Passion are highly regarded. His music displays a wide variety of influences ( expressionism, constructivism,hazz) and often reflects sensitivy to Czech folk music. Ot is characterized by the freedom of its melodies, the vigor of its rhythms, and the transparency of its textures. This diploma thesis deals of Martinů ´s little known one-act radio opera The Voice of the Forest ( Hlas Lesa). The libretto of the opera is written by the czech poet Vítězslav Nezval. This short experimental work was written specifically for radio performance in 1935. It called for a good articulation and different treatment of dramatic time than would be typical for a staged work. In contrast to the wildy extravagant libretto, the music is fine, lyric and tonal, expressing the characters ´emotions without irony, but with neverending optimism.
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Zajíček, Pavel. "Hlas volajícího na pouti." Master's thesis, Akademie múzických umění v Praze.Divadelní fakulta. Knihovna, 2017. http://www.nusl.cz/ntk/nusl-369365.

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Oswaldová, Petra. "Feldenkraisova metoda, dech a hlas." Doctoral thesis, Akademie múzických umění v Praze.Divadelní fakulta. Knihovna, 2014. http://www.nusl.cz/ntk/nusl-178087.

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The scope of the ?Feldenkrais method, breath and voice? dissertation thesis is the process of examining and recording circumstances, under which it is possible to interactively combine elements of movement, breathing and voice in a new approach that is primarily intended for group learning. In introduction, the author describes the theoretical and practical basis and presents main inspiration sources: learning by movement according to Dr. Moshé Feldenkrais and voice upbringing by Libuše Válková. These are followed by the basic terms integrating both approaches that are named in the context of practice and a philosophical overlap
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Drábková, Anna. "Hlas jako výzva k tvorbě." Master's thesis, Akademie múzických umění v Praze.Divadelní fakulta. Knihovna, 2015. http://www.nusl.cz/ntk/nusl-202442.

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This thesis clarifies the elementary terminology on the field of the voice and voice disorders, deals with the problem of voice formation and the function of voice-forming organs and addresses the issue of the influence of voice possibilities and its variability on the artworks. The author of the thesis tries to answer the question why the voice quality and option variability is so decisive for her work. The thesis is divided into three chapters. The first chapter explains the elementary knowledge about voice, the voice-forming organs necessary for voice expression, basic qualities of human voice and its development. The second chapter outlines the issue of voice disorders. The ones mainly described in detail are those which the author of the thesis is subjected to. These disorders are closely related to the artwork analysed in the third chapter. The third chapter addresses the way and level of voice influence over the artwork. The voice variability allowing one's self-reflection through various ways is the key topic. Voice options, their use and artwork impact are also discussed.
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Švarcová, Terezie. "Lidský hlas v tvorbě Arnolda Schönberga ve vybraných příkladech." Master's thesis, Akademie múzických umění v Praze.Hudební a taneční fakulta. Knihovna, 2014. http://www.nusl.cz/ntk/nusl-178014.

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The human voice holds a significant position in works of Arnold Schönberg. My dissertation focuses on the use of a voice technique, the so-called Sprechstimme (Spoken-voice) in the musical piece Pierrot Lunaire, op. 21 (1912). I confront the term Sprechstimme with the term Sprechgesang (Spoken-singing) in the very opening of my study. In addition, Schönberg's use of human voice in the pieces written before Pierrot, are briefly mentioned. I am peripherally exploring the other melodramas written by Schönberg, namely Ode to Napoleon Buonaparte, op. 41 (1942) and A Survivor from Warsaw, op. 46 (1947) at the conclusion of this dissertation. I am clarifying why the author has chosen this type of voice technique and also where it is used in musical and aesthetical contexts. I explain the term Sprechmelodie (Spoken-melody) in the area of analysis and focus on the composer's approach to the text material in the ambit of rhythmical component, articulation, dynamics, agogic and the verbal directions for the narrator. Sprechstimme represents one of two fundamental composers approaches towards the human voice and becomes some sort of parallel to the purely vocal composition attitude during the composition time.
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Koderová, Lucie. "Role představy, fantazie a imaginace v psychosomatickém pohledu na hlas." Master's thesis, Akademie múzických umění v Praze.Divadelní fakulta. Knihovna, 2014. http://www.nusl.cz/ntk/nusl-177896.

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This thesis is concerned with the use of idea, fantasy, and imagination during the process of formation of the natural voice. The thesis is divided into five chapters, which gradually points to connect the physical body with the mental processes and emphasizes the importance of developing images during the voice education process. The first chapter deals with the voice education, reference the history and philosophy, and also introduces the specifics during the voice-creation process. The second chapter introduces the field of psychosomatic disciplines from medical beginnings to its application in voice education, and describes the origins of voice disorders. The concept of idea, fantasy, and imagination is explained in the third chapter, and also their role in voice education is described there. The fourth chapter deals with children in three age periods and also children with special needs. This theoretical overview is utilized in the final, fifth chapter, which presents specific examples of working with imagery in voice education of children in these groups. This thesis provides a theoretical basis as psychosomatic methods of work with a voice, as well as examples of applications in a particular situation.
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Christensson, Ludvig. "Functional Shading Language : Kompilering av funktionsvärden, typinferens och automatisk generalisering till HLSL." Thesis, Högskolan i Skövde, Institutionen för informationsteknologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-15754.

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Rapporten beskriver design, utveckling och testning av det funktionella shaderspråket FSL i syftet att avgöra om funktionell paradigm gör shaderspråk enklare att förstå och använda än den existerande imperativa paradigmen. Implementationen presenterar tekniker för att kompilera de funktionella språkkonstruktionerna typinferens, funktionsvärden och automatisk generalisering till HLSL. För jämförelse introduceras också språket PSL, en imperativ motsvarighet till FSL. Resultatet bedöms genom ett blindtest där FSL och PSL presenteras till två separata grupper och testas genom tre provuppgifter. Undersökningen visade att personer som testade det funktionella språket svarade mer negativt på språkets designbeslut, men att båda grupperna presterade lika bra på uppgifterna. Förslag på hur arbetet kan användas som grund för en djupare studie om funktionell grafikprogrammering presenteras. Till sist diskuteras olika sätt att bygga på FSLs tekniska bas för att implementera andra funktionella språkverktyg.
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Thompson, Martin John. "Investigation of the effects of HLS5 : a novel member of the RBCC family." University of Western Australia. School of Medicine and Pharmacology, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0106.

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[Truncated abstract] Erythropoietin (Epo) is a glycoprotein hormone involved in the formation of erythrocytes, by controlling survival, differentiation and proliferation. The technique of cDNA Representational Difference Analysis was utilized to investigate J2E-NR cells that demonstrate a viability response to Epo, but not differentiation or proliferation. The aim of this project was to identify genes that may be upregulated in response to Epo-induced survival; however, no change in gene expression was detected. This was most probably because any changes were below the limit of detectability for the cDNA RDA technique, or the viability effect was mediated post-transcriptionally. Next, it was decided to investigate HLS5, a putative tumour suppressor that was identified in a myeloid variant of the J2E cell line and had been shown to cause apoptosis. A number of HeLa cell lines inducible for Hls5 expression using the tet-off system were produced; despite extremely low expression, Hls5 was shown to produce marked suppression of growth and proliferation, particularly in colony assays colony size and numbers were halved for one induced clone. … A number of haemopoiesis-associated genes were downregulated (viz. globin genes and the Epo receptor gene), which suggested Hls5s role in the myeloid variant of J2E cells, may be to suppress genes expressed in the erythroid lineage. In addition, several interferon-responsive genes were decreased in cells with elevated HLS5, suggesting it may play a role in negatively regulating interferon signaling. Online databases were also searched for information on HLS5, and showed that it is significantly downregulated in liver, lung and uterine cancers, supporting the proposition that HLS5 is a tumour suppressor gene. In summary, a number of approaches were taken to identify the effects of the Hls5 protein. It appears that it strongly suppresses proliferation and that this is likely mediated through an effect on mitosis. This may also result in apoptosis of overexpressing cells. It is possible that this is the mechanism through which HLS5 exerts its potential tumour suppressor function, as a number of tumour suppressors appear to be associated with mitosis/apoptosis control. Hls5 is also likely to have other functions in haemopoietic cells, which includes downregulation of erythroid-specific genes and suppression of interferon responses.
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Books on the topic "HLSS"

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Cieslar, Jiří. Hlas deníku. Praha: Torst, 2002.

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Zelinová, Hana. Hlas starých huslí. Bratislava: Slovenský spisovatel̕, 1988.

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Škvorecký, Josef. Hlas z Ameriky. Toronto, Ont., Canada: Sixty-Eight Publishers, 1990.

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Makaï, Sylvester D. Hlas dzvona bronzovoho: Pysnï. Novy Sad: Ruske slovo, 2007.

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Hásek, Jindřich. Rejstřík pro lidský hlas. Praha: Československý spisovatel, 1985.

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Remešová, Michaela. Karel Gott: Zlatý hlas z Prahy. Praha: Eminent, 2009.

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Škoda, Jan J. Pro hlas a pro dvě ruce. V Hradci Králové: Kruh, 1986.

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Musil, Jiří F. Tajemný hlas minulosti: Pověsti ze středního Polabí. Praha: Lidové noviny, 2001.

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Makuch, Andrij Borys. Hlus' Church: A narrative history of the Ukrainian Catholic Church at Buczacz, Alberta. [Edmonton]: Alberta Culture and Multiculturalism, 1989.

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Čapek, Karel. Tichý hlas: Néznamé i známé texty z roku 1938. Praha: Arsci, 2005.

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Book chapters on the topic "HLSS"

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Metze, Dieter, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, et al. "HLTS." In Encyclopedia of Molecular Mechanisms of Disease, 848. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6143.

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Metze, Dieter, Vanessa F. Cury, Ricardo S. Gomez, Luiz Marco, Dror Robinson, Eitan Melamed, Alexander K. C. Leung, et al. "HLHS." In Encyclopedia of Molecular Mechanisms of Disease, 848. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_8912.

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Blum, Ulrike, Hans Meyer, and Philipp Beerbaum. "Hypoplastisches Linksherzsyndrom (HLHS)." In Kompendium angeborene Herzfehler bei Kindern, 277–87. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-47867-7_27.

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Berman, Darren P., and Evan M. Zahn. "Hybrid Strategies (Non-HLHS)." In Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care, 1251–71. London: Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-4619-3_130.

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Banka, Puja, Diego Porras, John E. Mayer, and Sitaram M. Emani. "Single Ventricle (Non HLHS)." In Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care, 1861–83. London: Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-4619-3_42.

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Steven, James M., and Susan C. Nicolson. "Anesthetic Management for HLHS." In Developments in Cardiovascular Medicine, 167–91. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0253-1_10.

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Spray, Thomas L. "Staged Reconstruction for HLHS." In Developments in Cardiovascular Medicine, 89–103. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0253-1_6.

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Karl, Tom R. "Staged Reconstruction For HLHS." In Developments in Cardiovascular Medicine, 129–48. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0253-1_8.

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Gaynor, J. William. "Staged Reconstruction for HLHS." In Developments in Cardiovascular Medicine, 149–66. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0253-1_9.

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Vogt, J. "791 HLiS Lithium hydrogen sulfide." In Asymmetric Top Molecules. Part 3, 379–80. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-14145-4_213.

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Conference papers on the topic "HLSS"

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Dütsch, Fabian, Karim Djelassi, Michael Haidl, and Sergei Gorlatch. "HLSF." In SPLASH '14: Conference on Systems, Programming, and Applications: Software for Humanity. New York, NY, USA: ACM, 2014. http://dx.doi.org/10.1145/2686745.2686751.

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Qian, Y., J. L. Liu, M. Umezu, K. Itatani, and K. Miyaji. "A Study of Surgical Optimization for Congenital Heart Diseases Based on Computational Hemodynamic Analysis." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206443.

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Hypoplastic left heart syndrome (HLHS) is one kind of serious congenital heart diseases (CHD). With a small, underdeveloped left ventricle, a heart suffering from HLHS cannot effectively supply enough blood flow to provide for the needs of the body. In order to improve blood circulation, surgery for HLHS has to be carried out at a very early stage. In general, three-stage palliative surgical management for newborns is now widely accepted [1, 2]; Norwood, Glenn, and Fontan.
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Nasr, Amal, Aya Omar, Maha Alser, Huseyin Yalcin, and Fatiha Benslimane. "Unraveling Gene Expression Profiles of Cardiac Genes that Participate in Embryonic development of Congenital Heart Defects using Chick Embryo." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0196.

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Hypoplastic left heart syndrome (HLHS) is a rare but serious subtype of congenital heart defect (CHDs) at which the hemodynamics are disturbed. In this project, HLHS was introduced surgically by left atrial ligation (LAL) to embryonic chicks and the subsequent effects of it were studied. Different tests were done post-LAL to study cardiac morphology, function, and gene expression of cardiac markers.
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Oskin, Mark, Frederic T. Chong, and Matthew Farrens. "HLS." In the 27th annual international symposium. New York, New York, USA: ACM Press, 2000. http://dx.doi.org/10.1145/339647.339656.

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Jalali, Ali, C. Nataraj, Gerard F. Jones, and Daniel J. Licht. "Computational Modeling of Hypoplastic Left Heart Syndrome (HLHS) in Newborn Babies." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48825.

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Hypoplastic left heart syndrome (HLHS) is a congenital heart defect (CHD) in which left side of the heart is severely underdeveloped. To better understand this unique physiology, a computational model of the hypoplastic heart was constructed on the basis of compartmental analysis. Lumped parameter model of HLHS is developed based on the electrical circuit analogy. Model is made up of three parts: hypoplastic heart, pulmonary circulation and systemic circulation. Plots of blood pressure and flow for various parts of body show great match between predicted values and what we expected for the case of HLHS babies. Influence of patent ductus arteriosus (PDA) and ASD resistances on cardiac output and pulmonary to systemic flow was also studied. Results show that by increasing the PDA resistance causes more flow to pulmonary compartments and so the ratio increases. Blood flow increases by decreasing of pulmonary artery resistant. Increasing the PDA resistance causes decrease the cardiac output because of more resistance against blood occurs. Saturation increases by decreasing of pulmonary artery resistant.
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Oneppo, Michael. "HLSL shader model 4.0." In ACM SIGGRAPH 2007 courses. New York, New York, USA: ACM Press, 2007. http://dx.doi.org/10.1145/1281500.1281576.

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Hansen, Rico H., Asger M. Iversen, Mads S. Jensen, Torben O. Andersen, and Henrik C. Pedersen. "Modeling and Control of a Teletruck Using Electronic Load Sensing." In ASME 2010 10th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2010. http://dx.doi.org/10.1115/esda2010-25270.

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In mobile hydraulic application the actuating fluid power system is most commonly controlled using a hydro-mechanical control scheme called Hydraulic Load Sensing (HLS). However, with the demands for increased efficiency and controllability the HLS solutions are reaching their limits. Motivated by availability of electronic controllable fluid power components and the potential of increased dynamic performance and efficiency, this paper investigates how HLS can be replaced with electronic control, i.e. Electronic Load Sensing (ELS). The investigation is performed by taking a specific application, a teletruck, and replace the HLS control with ELS. To aid the controller design for the ELS system, a complete model of the teletruck’s articulated arm and fluid power system is developed. To show the feasibility, a preliminary control structure for the ELS system is developed. The controller is tested on the machine, validating that features such as pump pressure control, flow sharing and over pressure protection can be implemented using ELS and with improved energy efficiency.
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Ledezma, Job A., Victor J. De Negri, and Victor Barasuol. "Interaction Analysis Between a Hydraulic Load Simulator and a Pneumatic Positioning System." In ASME/BATH 2017 Symposium on Fluid Power and Motion Control. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/fpmc2017-4356.

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Pneumatic positioning systems (PPS) are widely used in fields were mechatronics applications exist. In order to improve the performance and robustness, either by designing new controllers or studying other characteristics of PPSs under different load conditions, a test bench with a load simulator is required. Hydraulic load simulators (HLS) are one of the most significant applications of hydraulic force control systems. The HLS aims to control the forces according to static and dynamic requirements. Typically, a force control system interacts with the external environment such that a good performance and robustness are not easily achieved. Different approaches are being discussed in the literature consisting on increasing the system compliance. System compliance can be controlled or modified in active or passive ways. Active compliance is obtained by force-based feedback control, allowing more flexibility to perform tasks where compliance is required. On the other hand, passive compliance is typically obtained by introducing mechanical elastic components between the actuator and the environment. In this paper, the influence of PPS compliance in the force controlled tuning of HLS is discussed. Because HLS is applying a controlled force against to a very compliant system like a pneumatic system, stable force responses could be expected. However, the dynamic interaction between the HLS with the PPS effected the force responses. This paper focuses in analyzing these effects, highlighting the design of PI and QFT controllers for force control based on these characteristics. Both of Systems are analyzed mathematically via simulation.
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Xuejun Li and Meng Xu. "Water simulation based on HLSL." In 2009 IEEE International Conference on Network Infrastructure and Digital Content (IC-NIDC 2009). IEEE, 2009. http://dx.doi.org/10.1109/icnidc.2009.5360906.

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Biglino, Giovanni, Hopewell Ntsinjana, Jennifer A. Steeden, Catriona Baker, Silvia Schievano, Sachin Khambadkone, Tain-Yen Hsia, Andrew M. Taylor, and Alessandro Giardini. "A Non-Invasive Study Using MR-Derived Wave Intensity Analysis to Highlight the Effect of Surgical Arch Reconstruction on Ventriculo-Arterial Coupling in Patients With Hypoplastic Left Heart Syndrome." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80262.

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Hypoplastic left heart syndrome (HLHS) is a congenital heart disease whose staged surgical palliation aims to progressively separate the systemic and pulmonary circulations. The first stage or Norwood procedure [1] involves surgical reconstruction of the aortic arch, usually with pulmonary homograft patch [2]. Recent evidence suggested that, because of this extensive reconstruction, HLHS patients have abnormal elastic properties [3] and reduced distensibility [4,5] of the ascending aorta. However, the impact of the reconstructed aorta and its abnormal elastic properties on ventricular mechanics, i.e. ventriculo-arterial coupling mismatch, has not been assessed. In the light of this mismatch, a change in impedance on the arterial side will reflect on the ventricular side and quantification of this phenomenon may provide mechano-energetic information for further understanding a complex physiology such as palliated HLHS with aortic arch surgical reconstruction. In this study we suggest that wave intensity analysis (WIA) is a valid method for studying ventriculo-arterial coupling, as WIA is a hemodynamic index able to assess the performance of the heart and its interaction with arterial system. Previously, distensibility quantification necessitated either of invasive [5] or cuff [4] arterial pressure monitoring, or multiple magnetic resonance (MR) images acquisitions for transit time wave speed calculation [6]. Instead, here we propose a non-invasive and semi-automated method based only on MR images analysis, with single slice analysis for estimate of local distensibility. The method, including WIA, was developed as a plug-in for DICOM viewer OsiriX, and applied to two cohorts of single ventricle patients.
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Reports on the topic "HLSS"

1

Nelson, Gena. High Leverage Practices in Special Education Synthesis Coding Protocol. Boise State University, March 2021. http://dx.doi.org/10.18122/sped134.boisestate.

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The purpose of document is to provide readers with the coding protocol that authors used to code 76 meta-analyses focused on students with or at-risk of disabilities. All of the included meta-analyses provided a summary statistic related to at least one of the High Leverage Practices (HLPs; McLeskey et al., 2017). ). The purpose of the systematic review of meta-analyses was to provide an initial investigation of the evidence supporting the effectiveness of the HLPs for students with, or at-risk for, a disability. This code book contains variable names, code options, and code definitions related to basic study information (i.e., authors, year of publication, journal), the details of each study, participant demographics, HLPs included in each study, and summary statistics. The mean interrater reliability across all codes using this protocol was 88% (range across categories = 84%–97%)
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O'Connell, Heath B. Isospin Symmetry Breaking within the HLS Model: A Full (rho, omega, phi) Mixing Scheme. Office of Scientific and Technical Information (OSTI), July 2001. http://dx.doi.org/10.2172/784974.

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