Academic literature on the topic 'HLV'

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Journal articles on the topic "HLV"

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Mayr, W. R., and M. Köhler. "Nebenwirkungen der Therapie mit Blut und Blutprodukten." Hämostaseologie 15, no. 04 (October 1995): 192–96. http://dx.doi.org/10.1055/s-0038-1655312.

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ZusammenfassungDie Übertragung von HlV-lnfektionen durch Blutkomponenten, die sich bislang noch nicht virusinaktivieren lassen, ist eine extrem seltene, aber typische unerwünschte Arzneimittelwirkung der Transfusion. Um dieses Restrisiko für HIV zu ermitteln, haben wir die Daten von 1985-1993 aus Wien und Göttingen ausgewertet. Im Jahr 1993 war die Prävalenzrate der HIV-lnfektion bei Erstspendern 1:7000 in Wien und 1:7900 in Göttingen. Die Inzidenz einer Neuinfektion unter den Dauerspendem war 1:42000 in Wien und 1:67 000 in Göttingen. Es wurde ein statistisches Modell zur Berechnung des Restrisikos entwickelt, das sowohl (1) das diagnostische Fenster der HIV-Teste, (2) die Sensitivität der Anti-HIV-Teste, als auch (3) globale Testfehler (bzw. Nichtberücksichtigung eines Testergebnisses) berücksichtigt. Wir ermittelten ein Restrisiko (für 3. Generations-anti-HIV-Tests mit einem diagnostischen Fenster von 22 Tagen) in Wien von 1:520000 und in Göttingen von 1:900000 für das Jahr 1993. Die gleichzeitig durchgeführten Look-back-Untersuchungen erbrachten HlV-lnfektionen bei 3 Empfängern (auf 1900000 Blutspenden) in Wien und 1 Empfänger in Göttingen (für 160000 Blutspenden).Mit Hilfe unseres Modells ist nicht nur eine Risikoabschätzung möglich, sondern es läßt sich auch der Effekt weiterer Maßnahmen zur Reduktion des Restrisikos errechnen.
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Sidorchuk, Roman, Sergey Vladimirovich Mkhitaryan, Boris Vladimirovich Musatov, Aleksey Aleksandrovich Meshkov, and Timur Alekseevich Tultaev. "The influence of high level values on brand preferences of student youth in Russia." International Journal of Retail & Distribution Management 46, no. 7 (July 9, 2018): 638–56. http://dx.doi.org/10.1108/ijrdm-01-2018-0006.

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Purpose The share of student youth, as consumers, is quite significant in the world. Considering that retailers view young consumers (including student audience) an important segment of the market, a substantial question is to study the effect of values on motivation consumer behavior. The purpose of this paper is to fill the lack of studies on motivational influence of “high-level values” (HLV) on young consumers. This research paper examines the motivational influence of HLV on brands in certain product categories-markers, to develop a methodology for segmenting consumers based on their clustering by values and evaluating brand preferences in different segments. Design/methodology/approach The sample was formed by the “snowball” method from first-year undergraduate students. The sample size involves 239 respondents. The research was carried out by the online survey method on the basis of a structured questionnaire. To obtain segments, the authors used hierarchical cluster analysis by the Ward method and the Euclidean distance method. The statistical significance of the differences in brand preferences between segments was checked in the conjugacy tables using the χ2 test at different significance levels. Findings Findings show clearly the possibility on the basis of HLV to identify segments of consumers, which allows obtaining the distribution of the perception of the brand. For a student audience received segments were: “Become a successful leader,” “become successful in a harmonious world,” “ascetic,” “the Hedonist,” Frequency analysis revealed an uneven distribution of preferences between the examined brands. At the same time, revealed the differences in the motivational significance HLV for brands in different product categories. Practical implications Retailers should use segmentation based on motivation influence of HLV for improving the effectiveness of communication of young consumers with brands. The solution of this problem will allow forming particular strategic behaviors of retailers occurring in the sphere of shaping relationships with young consumers. Originality/value It is one of the rare studies that investigate motivational influence of a complex of ten HLV on the young consumers. In this paper, the authors propose to use a methodology for young consumers segmentation based on clustering for HLV, and assessing brands preferences in different segments.
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Doerfler, Arnd, Tobias Engelhorn, Sabine Heiland, Thomas Benner, and Michael Forsting. "Perfusion- and diffusion-weighted magnetic resonance imaging for monitoring decompressive craniectomy in animals with experimental hemispheric stroke." Journal of Neurosurgery 96, no. 5 (May 2002): 933–40. http://dx.doi.org/10.3171/jns.2002.96.5.0933.

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Object. The aim of this study was to use two types of serial magnetic resonance (MR) imaging—perfusionweighted (PW) and diffusion-weighted (DW)—to monitor craniectomy in rats with hemispheric stroke. Methods. Focal cerebral ischemia was induced in 36 rats by using an endovascular method of occlusion of the middle cerebral artery (MCAO). Craniectomy was performed 4 or 24 hours later in 12 animals each. Twelve control animals underwent occlusion but did not receive treatment. Perfusion-weighted, DW, and T2-weighted MR images were obtained at 4, 24, 48, 72, and 168 hours postocclusion in all animals. Relative regional cerebral blood volumes and apparent diffusion coefficients (ADCs) were calculated for the cortex and basal ganglia. Hemispheric lesion volumes (expressed as percentages of total brain volumes; %HLV) as they appeared on DW and T2-weighted MR images and on histological slices stained with 2,3,5-triphenyltetrazolium chloride were compared. Neurological performances and infarct volumes measured 7 days postocclusion were used as study end points. Both PW and DW images demonstrated ischemic tissue 4 hours after MCAO in all animals. Early treatment by performing craniectomy significantly improved cortical perfusion (p < 0.01), whereas the same procedure conveyed no benefit to the basal ganglia. Compared with findings in control animals, the DW image—derived %HLV was significantly reduced (p < 0.01) and the cortical ADCs at 4 and 24 hours postocclusion were significantly higher in animals treated early (p < 0.05). Late treatment with craniectomy did not significantly affect cerebral perfusion. The correlation between the DW imaging—derived %HLV and the histologically derived %HLV at 4 to 72 hours postocclusion was good (r = 0.74), whereas at Day 7 postocclusion the %HLV was underestimated up to 41% on DW imaging. At 4 hours postocclusion T2-weighted imaging failed to demonstrate the ischemic lesion, whereas from 24 to 72 hours postocclusion the correlation between the T2-weighted imaging—derived %HLV and the histologically derived %HLV was good (r > 0.81). Neurological performance was significantly improved in animals treated using craniectomy. Conclusions. Early craniectomy significantly improves cortical perfusion through leptomeningeal collateral vessels, significantly reduces infarct size, and improves neurological performance in animals with experimental acute hemispheric infarction. Both PW and DW imaging are suitable for noninvasive monitoring of the effects of decompressive craniectomy.
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Shinjo, Masato, Kanae Akaiwa, Masashi Iwasaki, and Yoshimasa Nakamura. "An extended Fibonacci sequence associated with the discrete hungry Lotka–Volterra system." International Journal of Biomathematics 10, no. 03 (February 20, 2017): 1750043. http://dx.doi.org/10.1142/s1793524517500437.

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The integrable hungry Lotka–Volterra (hLV) system stands for a prey–predator model in mathematical biology. The discrete-time hLV (dhLV) system is derived from a time discretization of the hLV system. The solution to the dhLV system is known to be represented by using the Casorati determinant. In this paper, we show that if the entries of the Casorati determinant become an extended Fibonacci sequence at the initial discrete time, then those are also an extended Fibonacci sequence at any discrete time. In other words, the extended Fibonacci sequence always appears in the entries of the Casorati determinant under the time evolution of the dhLV system with suitable initial setting. We also show that one of the dhLV variables converges to the ratio of two successive extended Fibonacci numbers as the discrete time goes to infinity.
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Ács, Virág, István Nagy, and Tamás Donkó. "A Selection Index for Improving the Carcass Traits in the Pannon Large Rabbit Breed." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 67, no. 5 (2019): 1125–29. http://dx.doi.org/10.11118/actaun201967051125.

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Loin muscle volume and hind leg muscle volume measured by computer tomography are economically valuable traits in rabbit breeding. Hence, genetic parameters were calculated to these new selection criteria, and a two-trait selection index was created in order to modify the current selection process of the Pannon large rabbit breed. The evaluated animals (n = 312) were randomly selected from 2014 and 2018, and the total number of animals in the pedigree file was 2758. Loin muscle volume (LMV) and hind leg muscle volume (HLV) were analyzed in a two-trait animal model. The estimated heritability for LMV was h2 = 0.4 and h2 = 0.42 for the HLV respectively. The selection index was created with desired gains by improving each trait in the selection criteria with one additive genetic standard deviation and the final index was Z transformed. Correlation coefficients between the index and the examined traits were high, 0.86 for LMV and 0.87 for HLV, thus this method could be announced into the breeding program.
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Caboral Stevens, Meriam, Godfrey Aneke, and Andrew Neplock. "The review of pre-exposure prophylaxis (PreP) for HIV prevention." Cultura del cuidado 11, no. 1 (June 1, 2014): 50–59. http://dx.doi.org/10.18041/1794-5232/cultrua.2014v11n1.3808.

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Human lmmunodeficiency Virus (HlV) epidemic continues to represent a major global health issue. Today, there are several tools available to prevent the spread of HIV infection. However, there are several constraints to the current prevention strategies including low condom use, low acceptance of testing, low awareness of vulnerability and more emphasis on treatment. Prevention strategy is redirected towards reducing acquisition of HIV. Pre-exposure prophylaxis or PrEP is the latest groundbreaking innovation in biomedical research in the prevention of HIV transmission.The purpose of this paper is to review preex ding the current guidelines in the use of PreP.
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Makiala-Mandanda, Sheila, Frédéric Le Gal, Nadine Ngwaka-Matsung, Steve Ahuka-Mundeke, Richard Onanga, Berthold Bivigou-Mboumba, Elisabeth Pukuta-Simbu, et al. "High Prevalence and Diversity of Hepatitis Viruses in Suspected Cases of Yellow Fever in the Democratic Republic of Congo." Journal of Clinical Microbiology 55, no. 5 (February 15, 2017): 1299–312. http://dx.doi.org/10.1128/jcm.01847-16.

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ABSTRACTThe majority of patients with acute febrile jaundice (>95%) identified through a yellow fever surveillance program in the Democratic Republic of Congo (DRC) test negative for antibodies against yellow fever virus. However, no etiological investigation has ever been carried out on these patients. Here, we tested for hepatitis A (HAV), hepatitis B (HBV), hepatitis C (HCV), hepatitis D (HDV), and hepatitis E (HEV) viruses, all of which can cause acute febrile jaundice, in patients included in the yellow fever surveillance program in the DRC. On a total of 498 serum samples collected from suspected cases of yellow fever from January 2003 to January 2012, enzyme-linked immunosorbent assay (ELISA) techniques were used to screen for antibodies against HAV (IgM) and HEV (IgM) and for antigens and antibodies against HBV (HBsAg and anti-hepatitis B core protein [HBc] IgM, respectively), HCV, and HDV. Viral loads and genotypes were determined for HBV and HVD. Viral hepatitis serological markers were diagnosed in 218 (43.7%) patients. The seroprevalences were 16.7% for HAV, 24.6% for HBV, 2.3% for HCV, and 10.4% for HEV, and 26.1% of HBV-positive patients were also infected with HDV. Median viral loads were 4.19 × 105IU/ml for HBV (range, 769 to 9.82 × 109IU/ml) and 1.4 × 106IU/ml for HDV (range, 3.1 × 102to 2.9 × 108IU/ml). Genotypes A, E, and D of HBV and genotype 1 of HDV were detected. These high hepatitis prevalence rates highlight the necessity to include screening for hepatitis viruses in the yellow fever surveillance program in the DRC.
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Lesar, Sharon, and Yvonne A. Maldonado. "The Impact of Children with HIV Infection on the Family System." Families in Society: The Journal of Contemporary Social Services 78, no. 3 (June 1997): 272–79. http://dx.doi.org/10.1606/1044-3894.775.

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The authors examined the effects of HIV infection on the family system as reported by 48 caregivers of HlV-exposed children. Respondents completed the Impact on Family Scale (IFS) as part of their participation in the study. Results showed that the psychological burden of the illness was significantly related to the child's HIV status; financial burden, social/familial Impact, and psychological burden of the Illness were significantly related to the caregiver's HIV status; psychological burden and social/familial impact differed as a function of the child's and caregiver's HIV status; and the Impact of HIV infection differed as a function of the caregiver relationship. Implications of the findings for service delivery are discussed.
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Christiansen, Claus Bohn, Torben E. Jessen, Claus Nielsen, and Poul Staun-Ohen. "False Negative Anti-HIV-1/HlV-2 ELlSAs in Acute HIV-2 Infection." Vox Sanguinis 70, no. 3 (April 1996): 144–47. http://dx.doi.org/10.1111/j.1423-0410.1996.tb01312.x.

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Yang, Aili, Ping Li, and Jingrong Zhong. "Facile preparation of low-cost HKUST-1 with lattice vacancies and high-efficiency adsorption for uranium." RSC Advances 9, no. 18 (2019): 10320–25. http://dx.doi.org/10.1039/c9ra01427f.

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Dissertations / Theses on the topic "HLV"

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Shazi-Mweli, Protasia Lily Bathelile. "Educators' attitudes towards HlV/AIDS at rural schools." Thesis, University of Zululand, 2010. http://hdl.handle.net/10530/1132.

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Submitted to the Faculty of Education in fulfillment of the requirements for the Master of Education in the Department of Educational Psychology and Special Education at the University of Zululand, South Africa, 2010.
One of the most devastating diseases in. modem history as measured in terms of loss of human life is the HIV/AIDS pandemic - Approximately 200 million people have already died. Sub- Sahara Africa is the most affected with South Africa severely affected with an estimated 6 million HIV positive South Africans and 2.5 million already dead from AIDS or related illnesses. This study, located at several primary and secondary schools in the deep rural areas of the Scottsburgh circuit, KwaZulu-Natal, South Africa, was undertaken to investigate the trend that, despite a higher level of knowledge and exposure to information about HIV/AID amongst educators and despite comprehensive campaigns to fight HIV/AIDS, an increasing number of educators are still dying from the disease. In this study it is assumed that knowledge alone is not enough and that attitude change is central to HIV/AIDS prevention since attitudes influence the way in which persons behave. The following research questions are asked: What is the nature of educators' attitudes towards HIV/AIDS, and, are the educators' attitudes towards HIV/AIDS influenced by variables such as age, gender, religion, experience and qualification? Thus the study aims to: determine the nature of educators' attitudes towards HIV/AIDS, and find out whether or not educators' attitudes towards HIV/AIDS are influenced by characteristics such as, gender, age, experience, religion, and qualification. To determine this, a quantitative study was conducted with 71 secondary and primary school educators in the rural area of KwaZulu Natal, Scottsburgh district. The survey, a cross sectional design, involved administering a fixed response questionnaire (Likert scale type) categorized into five scales, which described the nature of educators' attitudes towards HIV/AIDS. The study revealed that there was no significant difference amongst the sampled educators' attitudes towards HIV/ADS, and that these attitudes were mostly negative. This difference was also not influenced by educators' age, gender, qualification, experience or religion. The study found that educators were still discriminating, reluctant to test themselves and disclose their HIV/AIDS status, which may be related to the failure of HIV/AIDS prevention strategies. The campaign to stop the spread of HIV/AIDS in schools and m communities appears to be jeopardized by such attitudes of educators. The following was recommended: the cascading system of training educators did not work and therefore the Department of Education must ensure that every educator has an opportunity to receive training in HIV/AIDS information; that support systems (emotional, psychological, medical) for those educators infected and affected by HFV/AIDS be made available; financial allocations to HIV/AIDS prevention programmes should be increased but with better fmancial control; employment of full-time co-ordinators who are knowledgeable; provision of incentives to encourage educators to test for HIV/AIDS and programmes that provide social skills training needed for behavioural change, as well as those that aim at reducmg stigraatization, ostracism and discrimination of individuals infected. The researcher suggests that an immediate, urgent strategy to address educator attitudes towards the disease is required from the relevant government departments.
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Costa, Cintia Bezerra Almeida. "Polimorfismo do HLA-G na coinfecção HIV/HCV." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/22/22132/tde-21052014-181750/.

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O objetivo geral da pesquisa foi associar os polimorfismos do gene HLA-G (região 3\' NT) com a coinfecção HIV/HCV e com os grupos (HIV, HCV e controles saudáveis). Trata-se de um estudo transversal, comparativo, descritivo. Participaram do estudo, 560 indivíduos, sendo 156 controles saudáveis, 102 coinfetados HIV/HCV, 186 infectados pelo HIV e 116 por HCV. Para a identificação dos polimorfismos, o DNA genômico foi extraído do sangue total e a genotipagem feita por PCR e visualizada em gel de poliacrilamida a 7%, no qual o polimorfismo de 14pb foi identificado, e por sequenciamento os outros sete SNPs. Os resultados sociodemográficos apontam que a amostra na sua grande maioria foi composta por indivíduos adultos e do sexo masculino. No que diz respeito à cor da pele, na comparação entre os grupos HCV e HIV/HCV, observou-se um maior número de coinfectados apresentando a cor preta e parda do que nos monoinfectados (P=0,0001). Com relação à categoria de exposição para aquisição do HIV, na comparação entre os grupos HIV e HIV/HCV, observou-se diferença significante na transmissão por via heterossexual, sendo sua frequência maior no grupo HIV (P=0,0000). No caso da comparação entre os grupos HCV e HIV/HCV, observou-se também diferença na transmissão heterossexual, sendo sua frequência significantemente maior no grupo HIV/HCV (P=0,0001). Quanto aos achados relacionados ao genótipo do HCV, na comparação entre os grupos HCV e HIV/HCV, o genótipo 1a apresentou frequência maior nos coinfectados (P=0,0001). No que diz respeito à carga viral do HIV, na comparação entre os grupos HIV e HIV/HCV, o grupo da monoinfecção apresentou maior carga viral do que o grupo da coinfecção (P=0,0350). Com relação ao grau de fibrose hepática, na comparação entre os grupos HCV e HIV/HCV, o grupo da coinfecção tem mais fibrose leve do que o grupo da monoinfecção (P=0,0009). Quanto aos polimorfismos genéticos da região 3\' NT do HLA-G, foi encontrado que o genótipo de heterozigose Del/Ins de 14 pb apresentou diferença significante nos indivíduos coinfectados pelo HIV/HCV (P=0,0216) quando comparados com o grupo controle. Em relação ao SNP +3003, a comparação dos grupos HCV e controle saudável mostrou que alelo +3003T apresentou uma frequência significantemente maior no grupo HCV (P=0,0147); o genótipo +3003C/T apresentou uma frequência maior no grupo controle (P=0,0095); o genótipo +3003T/T estava maior no grupo HCV (P=0,0095). A comparação entre os grupos HIV e HCV mostrou que a frequência do alelo +3003C estava maior no grupo HIV (P=0,0463); e o genótipo +3003T/T apresentou uma frequência maior no grupo HCV (P=0,0494). A frequência do genótipo +3187A/A estava maior no grupo HIV/HCV em comparação ao HIV (P=0,0193); e do +3187A/G estava maior no grupo HIV (P=0,0187). O genótipo +3196C/G apresentou frequência significamente maior no grupo HIV do que no controle saudável (P=0,0213). A UTR-10, na comparação entre os grupos HIV e controle, mostrou frequência maior no grupo HIV (P=0,0044); quando comparados os grupos HIV/HCV e HIV, frequência foi maior no grupo HIV (P=0,0300) e na comparação entre os grupos HIV e HCV, sua frequência também foi maior no grupo HIV (P=0,0140). A UTR-4, na comparação dos grupos HCV e controle saudável, revelou uma frequência maior no grupo controle (P=0,0147). A UTR-9, na comparação dos grupos HIV/HCV e HIV, mostrou frequência maior no grupo HIV/HCV (P=0,0460). Em relação aos dados clínicos, a presença do alelo T na posição +3035 foi significantemente associada à maior carga viral do HCV, acima de 400.000 cópias/mL (P=0,0244). Em relação aos tipos de genótipos do HCV, a presença do alelo +3027C foi associada ao subtipo 1a do HCV (P=0,0109). Adicionalmente, a presença do genótipo C/C na posição +3027 também foi significantemente associada com o subtipo 1a do HCV (P=0,0015). Ainda, o alelo A do SNP +3187 foi significantemente associado com os outros genótipos do HCV, excluindo o 1a (P=0,0369). Embora não esteja totalmente esclarecida a função do gene HLA-G, estudos têm sido desenvolvidos para melhor elucidar sua função nos contextos fisiológicos, como gestação, e patológicos, como tumores, transplantes, doenças inflamatórias e infecciosas. Tais estudos procuram ampliar o conhecimento sobre o sistema imunológico e contribuem para o desenvolvimento de novas estratégias diagnósticas e terapêuticas. Os resultados do presente estudo contribuem para a ampliação do conhecimento sobre os polimorfismos da região 3\' NT do gene HLA-G, na coinfecção HIV/HCV. Como também, na melhoria da assistência de enfermagem que deve buscar reduzir a morbimortalidade pela referida patologia. Porém, ainda há um longo percurso a ser percorrido na compreensão dos fatores imunogenéticos envolvidos na coinfecção pelo HIV/HCV
The general objective of the research was to associate the polymorphism of the gene HLA-G (region 3\' NT) with the co-infection HIV/HCV and with the groups (HIV, HCV and healthy control). It is a cross-sectional, comparative, descriptive study. 560 individuals participated of the study, being 156 healthy control individuals, 102 co- infected HIV/HCV, 186 infected by HIV and 116 by HCV. For identifying the polymorphisms, the genomic DNA was extracted from the total blood and the genotyping was made by PCR and visualized in gel of polyacrylamide at 7%, in which the polymorphism of 14pb was identified, and by sequencing the other seven SNPs. The social demographic results point that the most of the sample was composed by male adult individuals. Regarding the color of the skin, in the comparison between the groups HCV and HIV/HCV, a bigger number of co-infected with black skin and brown-skinned was observed than in the mono infected (P=0,0001). Regarding to the category of exposition for acquisition of the HIV, in the comparison between the groups HIV and HIV/HCV, a significant difference was observed in the transmission through heterosexual exposition, being its frequency bigger in the group HIV (P=0,0000). In the case of the comparison between the groups HCV and HIV/HCV, the difference in the heterosexual transmission was also observed, being its frequency significantly higher in the group HIV/HCV (P=0,0001). About the finding related to the genotype of the HCV, in the comparison between the groups HCV and HIV/HCV, the genotype 1a presented higher frequency in the co- infected (P=0,0001). Regarding to the viral load of the HIV, in the comparison between the groups HIV and HIV/HCV, the group of the mono infection presented bigger viral load that the group of the co-infection (P=0,0350). Regarding to the level of hepatic fibrosis, in the comparison between the groups HCV and HIV/HCV, the group of co-infection has a lighter fibrosis that the group of the mono infection (P=0,0009). Regarding to the genetic polymorphisms of the region 3\' NT of the HLA-G, it was found that the genotype of heterozygosis Del/Ins of 14 pb, presented significant difference in the individuals co-infected by the HIV/HCV (P=0,0216) when compared with the control group. About the SNP +3003, the comparison of the groups HCV and healthy control, it was showed that the allele +3003T presented a significant higher frequency in the group HCV (P=0,0147); the genotype +3003C/T presented a higher frequency in the control group (P=0,0095); the genotype +3003T/T was bigger in the group HCV (P=0,0095). The comparison between the groups HIV and HCV showed that the frequency of the allele +3003C was bigger in the group HIV (P=0,0463); and the genotype +3003T/T presented a bigger frequency in the group (P=0,0494). The frequency of the genotype +3187A/A was bigger in the group HIV/HCV in comparison to the HIV (P=0,0193); and of the +3187A/G was bigger in the group HIV (P=0,0187). The genotype +3196C/G presented frequency significantly bigger in the group HIV than in the healthy control (P=0,0213). The UTR-10, in comparison between the groups HIV and control, showed bigger frequency in the group HIV (P=0,0044); when compared the groups HIV/HCV and HIV, frequency was bigger in the group HIV (P=0,0300) and in the comparison between the groups HIV and HCV, its frequency was also bigger in the group (P=0,0140). The UTR-4, in the comparison of the groups HCV and healthy control, revealed a bigger frequency in the control group (P=0,0147). The UTR-9, in comparison of the groups HIV/HCV and HIV, showed bigger frequency in the group HIV/HCV (P=0,0460). Regarding to the clinical data, the presence of the allele T in the position +3035, was significantly associated to bigger viral load of the HCV, above 400.000 copies /mL (P=0,0244). About the types of genotypes of the HCV, the presence of the allele +3027C was associated with the subtype 1a of the HCV (P=0,0109). Additionally, the presence of the genotype C/C in the position +3027 was also significantly associated with the subtype 1a of the HCV (P=0,0015). Still, the allele A of the SNP +3187 was significantly associated with the other genotypes of the HCV, excluding the 1a (P=0,0369). Although the function of the gene HLA-G, is not totally clarified, studies have been developed for better elucidate its function in the physiological contexts, like gestation, and pathological, such as tumours, transplants, infectious and inflammatory diseases. These studies aim to extend the knowledge about the immunological system and contribute for the development of new diagnostic and therapeutic strategies. The results of this study contribute for enhancement of the knowledge about the polymorphisms of the region 3\' NT of the gene HLA-G, in the co-infection HIV/HCV. As well as, in the improvement of the assistance of nursing that must seek reducing the morbid mortality by the pathology referred. However, there is still a long path to be followed in the comprehension of the immunogenic factors involved in the co-infection by the HIV/HCV
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Soares, Sampaio Aletheia. "Marcadores sorológicos para os vírus da hepatite B e C em pacientes HIV-positivos atendidos no Hospital Universitário Oswaldo Cruz." Universidade Federal de Pernambuco, 2005. https://repositorio.ufpe.br/handle/123456789/7445.

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A ocorrência de co-infecção pelo HIV e hepatites B e C tem sido relatada desde a era- HAART (do inglês Highly Active Antinetrovial Therapy), quando a mortalidade nas pessoas infectadas pelo HIV começou diminuir. Como conseqüência do fato de terem as mesmas rotas de transmissão, a co-infecção do HBV ou HCV em pessoas infectadas pelo HIV tem aumentado e tornou-se um problema de saúde pública. No Brasil, a prevalência média da coinfecção HIV e hepatites, encontrada pelo Ministério da Saúde é em torno de 40%, com a maioria em grupos de usuários de drogas. Freqüências variáveis de co-infecção têm sido relatadas, dependendo da população e da região estudada. O objetivo principal deste estudo foi identificar a freqüência de marcadores sorológicos para hepatite B e C em pacientes infectados pelo HIV, acompanhados em um hospital escola e os possíveis fatores associados à presença de tais marcadores. Quatrocentos e vinte e nove pacientes foram estudados, de ambos os sexos e com idade variando entre 18 a 77 anos. Os participantes respondiam um questionário específico, com características sócio-demográficas e tinham uma amostra de sangue testada para os marcadores HBsAg, Anti-HBc total e Anti-HCV, utilizando a técnica MEIA-Axym-Abbott. A freqüência encontrada de marcadores foi 10,3% para o HBsAg, 38,7% para o Anti-HBc total e 10,7% para o Anti-HCV. Dentre os pacientes, 1,4% possuíam tanto HBsAg quanto Anti-HCV positivos. Não houve associação significante estatisticamente entre as variáveis parceiro homossexual, uso de drogas endovenosas, ingesta de álcool, tatuagem ou piercing, cirurgia, procedimentos invasivos e hemotransfusão e a infecção pelo HBV, expressa pela positividade do HBsAg. A única variável que mostrou associação com infecção pelo HBV foi uso de drogas inalatórias. Nenhuma destas variáveis, incluindo, parceiro homossexual, uso de drogas endovenosas, uso de drogas inalatórias, ingesta de álcool, tatuagem ou piercing, cirurgia, procedimentos invasivos e hemotransfusão tiveram associação significativa estatisticamente com a presença do Anti-HCV. Este estudo encontrou freqüências comparáveis com outros relatados no Brasil, mas com freqüências de coinfeccção menores que aqueles das regiões Sul e Sudeste. Entretanto, nenhuma associação específica com comportamentos de risco foi encontrada neste estudo, mostrando importante diferença quando comparado com estudos realizados em outras regiões do Brasil
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Dukers, Nicole Helena Theodora Maria. "Epidemiology of HIV-1, HHV-8 and HSV among homosexual men." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2002. http://dare.uva.nl/document/62498.

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Bertol, Bruna Cristina. "Expressão da molécula HLA-G e polimorfismos da região codificadora do gene HLA-G em pacientes infectados pelo vírus da hepatite C (HCV) apresentando ou não a coinfecção pelo vírus da imunodeficiência humana (HIV)." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17147/tde-10012017-112046/.

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A hepatite C, causada pelo vírus da hepatite C (HCV), afeta milhões de pessoas no mundo. A transmissão do HCV é semelhante ao HIV, justificando a alta taxa de prevalência da coinfecção. Pacientes coinfectados HCV/HIV apresentam maior taxa de progressão da fibrose hepática e da mortalidade, em comparação aos pacientes monoinfectados com HCV. Assim, o estudo de genes e/ou moléculas que controlam a resposta imune é pertinente. No presente estudo, avaliamos o papel do antígeno leucocitário humano G (HLA-G), molécula com reconhecida atividade imunomoduladora, capaz de inibir a ativação das células T e a atividade citotóxica das células Natural Killers (NK) e linfócitos T CD8+, além de induzir a formação células T reguladoras. Nós investigamos 216 pacientes monoinfectados pelo HCV, 135 pacientes coinfectados HCV-HIV e 152 indivíduos não infectados. A variabilidade do gene HLA-G foi avaliada por sequenciamento de Sanger e a expressão hepática da molécula por imunoistoquímica. A expressão de HLA-G foi observada somente no tecido hepático dos pacientes, principalmente nos hepatócitos. O aumento de expressão de HLA-G foi associado com avanço da fibrose e da atividade necroinflamatória no fígado de ambos os grupos de pacientes. Idade igual ou superior a 40 anos e a cor de pele não-branca também foram associados com aumento da expressão hepática da molécula nos pacientes HCV. Outros fatores do hospedeiro analisados como gênero e genótipo do HCV não foram associados com o nível de expressão de HLA-G no fígado. A frequência do alelo HLA-G*01:01:01:01 estava aumentada nos pacientes HCV e do alelo G*01:05N diminuída nos pacientes coinfectados HCV-HIV, porém, não houveram associações significantes entre a variabilidade genética de HLA-G e a expressão hepática de HLA-G. O presente estudo contribui para a ampliar os conhecimentos acerca da participação da molécula HLA-G na hepatite C crônica, associado ou não com infecção pelo HIV.
Hepatitis C, caused by the hepatitis C virus (HCV), affects millions of people worldwide. The transmission of HCV is similar to HIV, which explains the high prevalence of coinfection. HCV-HIV coinfected patients have higher rate of liver fibrosis progression and mortality when compared to HCV monoinfected patients. Thus, the study of genes and/or molecules that control the immune response is relevant. In the present study, we evaluated the role of human leukocyte antigen G (HLA-G), a molecule known by its immunomodulatory activity, which is capable to inhibit T cell activation and cytotoxic activity of natural killer (NK) cells and CD8+ T cells, in addition to inducing the formation of regulatory T cells. We studied 216 HCV patients, 135 HIV-HCV coinfected patients and 152 uninfected individual. The variability of the HLA-G gene was evaluated by Sanger sequencing and the hepatic expression of the molecule by immunohistochemistry. The HLA-G expression was observed only in liver tissue of patients, mainly in hepatocytes. The increased HLA-G expression was associated with increased liver fibrosis and necroinflammatory activity in both groups of patients. The age greater than or equal to 40 years and the non-white skin color were also associated with increased hepatic expression of the molecule in the HCV patients. Other host factors analyzed as gender and HCV genotype were not associated with the level of HLA-G expression in the liver. The frequency of HLA-G*01:01:01:01 allele was increased in HCV patients and G*01:05N decreased in HCV-HIV coinfected patients, however, there was no significant association between the genetic variability of HLA-G and HLA-G liver expression. The present study contributes to expand the knowledge regarding the participation of HLA-G in chronic C hepatitis, associated or not with the HIV infection.
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Vilar, Fernando Crivelenti. "Expressão do HLA-G no tecido hepático de pacientes coinfectados com HIV/HCV." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/17/17138/tde-24082014-194222/.

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A doença hepática crônica causada pelo vírus da hepatite C (HCV) tornou-se, nos últimos anos, uma das principais comorbidades dos pacientes portadores do vírus da imunodeficiência humana (HIV) nos países desenvolvidos. Os pacientes coinfectados com HIV/HCV apresentam uma progressão mais rápida para a cirrose e as suas complicações que os pacientes monoinfectados com HCV. Embora os mecanismos responsáveis por esta evolução não estejam totalmente esclarecidos, a expressão da molécula de HLA-G, um HLA de classe Ib não clássico, que tem propriedades bem reconhecidas na regulação negativa da resposta imune, pode estar relacionada à progressão da doença hepática. Os objetivos deste trabalho foram analisar o perfil de expressão de HLA-G em tecido hepático de pacientes coinfectados HIV/HCV e identificar possíveis variáveis do hospedeiro, do HCV e do HIV que possam estar relacionadas com a expressão de HLA-G na biópsia hepática. Para isso, 57 amostras de biópsia hepática de pacientes coinfectados com HIV/HCV, nas quais a imuno-histoquímica para HLA-G foi realizada, foram analisadas retrospectivamente quanto à expressão desta molécula no tecido hepático. Avaliaram-se também outras características histopatológicas da biópsia como grau de fibrose, atividade inflamatória, deposição de ferro e gordura. Determinou-se o polimorfismo de inserção ou deleção de 14 pares de bases da região 3` não traduzida do exon 8 do gene do HLA-G, que está relacionada com a produção de RNA-mensageiro, em 43 destes pacientes, além do polimorfismo de IL-28B, relacionado com a resposta ao tratamento do HCV, em 44 deles. Características bioquímicas e virológicas, tanto do HIV quanto do HCV também foram avaliadas. O genótipo 1 do HCV foi o mais prevalente (87,75%), especialmente o subgenótipo 1a (60%). A expressão do HLA-G foi observada em 38 (66,7%) amostras de fígado, e foi mais frequente em estágios moderados e severos de fibrose do que em estágios mais leves (94,1% x 55%, P < 0,01). Não houve relação entre a expressão do HLA-G e os outros parâmetros estudados. Embora a progressão para a cirrose no contexto da coinfecção por HIV/ HCV seja um processo complexo, modulado por muitos factores, a associação da intensidade de fibrose com a expressão do HLA-G pode indicar que a expressão desta proteína desempenha um importante papel nos mecanismos que contribuem para a progressão da doença, por meio da regulação negativa da resposta imune contra o HCV na coinfecção pelo HIV.
Chronic liver disease induced by hepatitis C virus (HCV) infection has recently become one of the most common comorbidities in patients who are infected with the human immunodeficiency virus (HIV) in developed countries. HIV/HCV coinfected patients show faster progression to cirrhosis and its complications than the HCV monoinfected patients. Even though the responsible mechanisms for this evolution have not been entirely clarified yet, the expression of the HLA-G molecule, a HLA from the non-classic Ib class, with well-known properties of negatively regulating the immune response, may be related to the liver disease progression. The aims of the present work were to analyze the HLA-G expression profile in the liver micro ambience of HIV/HCV coinfected patients and to identify possible host factors, HIV or HCV, that may be related to the HLA-G expression on the liver biopsy. For this purpose, 57 liver biopsies of HIV/HCV coinfect patients, in which immunohistochemistry for HLA-G had been performed, were retrospectively analyzed according the HLA-G expression on the hepatic tissue. Other histopathological features in the liver biopsies, such as fibrosis degree, inflammatory activity, iron deposition and fat were also evaluated. The polymorphism of insertion or deletion in 14-base pairs of the 3`non-translated region of exon 8 of the HLA-G gene, which is related to the production of HLA-G messenger RNA, was evaluated in 43 of the patients. Also, the polymorphism of IL-28B, related to the response to HCV treatment, was evaluated in 44 of them. Biochemical and virological features of HIV and HCV were also evaluated. The HCV genotype 1 was the most prevalent (87.75%), especially the subgenotype 1a (60%). The expression of HLA-G was observed in 38 (66.7%) samples of the liver biopsies, and it was most frequent in moderate and severe stages of fibrosis than in the mild stages (94.1% x 55%, P < 0.01). There was no established relationship between HLA-G and other parameters studied. Although the progression to cirrhosis in the context of HIV/HCV coinfection is a complex process modulated by many factors, the association of HLA-G expression with the intensity of the liver fibrosis may indicate the protein expression play an important role in the mechanisms that contribute to the progression of the disease, through the negative regulation of the immune response against HCV setting of a coinfection with HIV.
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Souza, Iury Oliveira. "Validação de ensaio imunocromatográfico para a detecção múltipla de anticorpos específicos contra HIV, HBV e HCV." reponame:Repositório Institucional da UFBA, 2013. http://www.repositorio.ufba.br/ri/handle/ri/11787.

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Cerca de 33,3 milhões de pessoas apresentam infecção pelo Human Immunodeficiency Virus (HIV) no mundo; 180 milhões estão infectados pelo Hepatitis C Virus HCV e estima-se que 360 milhões apresentem infecção ativa pelo Hepatitis B Virus (HBV). Outra realidade mundial é a co-infecção entre esses vírus. Os dados mostram a importância global dessas viroses e a urgência do desenvolvimento de novos ensaios de diagnóstico sensíveis, específicos, rápidos e de baixo custo, que possam atender à demanda de entidades públicas inseridas em programas para prevenção e diagnostico dessas doenças. O presente trabalho consiste em validação relativa de um novo teste imunocromatográfico desenvolvido pela empresa canadense Medmira para detecção de anticorpos específicos contra HIV, HCV e HBV. Os resultados encontrados foram extremamente favoráveis para a detecção de anticorpos específicos para HIV, apresentando 98,6% de sensibilidade e 100% de especificidade. Para o anti-HBV a sensibilidade e especificidade encontradas foram de 90,0% e 98,6%, e de 86,3% e 100%, para anti-HCV, respectivamente. Nenhuma reatividade cruzada foi encontrada e a reprodutibilidade e repetitividade foram de 100%. O índice kappa e a acurácia global do teste foram de 0,91 (0,88-0,94) e 95,5% (93,5-97,5), respectivamente. Conclui-se que o ensaio imunocromatográfico é clinicamente útil em triagens rápidas para detecção de anticorpos anti-HIV, HCV e HBV.
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Costa, Marjory Lucia Firmino da. "Expressão das moléculas HLA-E nas lesões intraepiteliais cervicais em mulheres portadoras do HPV com ou sem a infecção pelo HIV-1." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/22/22132/tde-04042017-152909/.

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Entre mulheres com HIV/AIDS há um maior número de casos de infecções persistentes pelo HPV contribuindo para um risco aumentado do desenvolvimento de lesões intraepiteliais escamosas cervicais. Ademais, a expressão anormal de moléculas HLA-E pode modular o sistema imunológico através da ligação com o receptor inibitório (CD94/NKG2A) ou estimulatório (CD94/NKG2C) de células NK e linfóticos T CD8+, diminuindo imunovigilância favorecendo a evasão de céulas infectadas por vírus. Diante da escassez de estudos avaliando a molécula HLA-E na interação com o HPV, mais especificamente na infecção pelo HIV-1, este estudo teve como objetivo avaliar a expressão de HLA-E em lesões intraepiteliais cervicais em mulheres portadoras do HPV, apresentando ou não a infecção pelo HIV-1. Trata-se de um estudo transversal, ao qual foram submetidos ao processo imunohistoquímico tecido do colo do útero parafinado de 67 mulheres infectadas pelo HIV-1 e 62 mulheres não infectadas, todas com lesão intraepitelial cervical com HPV, o qual foi tipificado. A expressão da molécula HLA-E foi analisada quantitativamente como sem expressão, de 1% a 30%, de 31% a 70% e de 71% a 100%. Os resultados mostraram que a infecção por herpes vírus foi maior entre as participantes HIV+ (P=0,005). Na análise imunohistoquímica, ficou evidente que as lesões intraepiteliais cervicais de mulheres infectadas pelo HIV-1 apresentaram redução na expressão da molécula HLA-E de 31% a 100% em comparação com mulheres sem a infecção pelo HIV- 1 (P=0,001), sugerindo que essa redução possa ser um mecanismo de escape viral, que acarreta a redução da apresentação de peptídeos virais para os linfócitos T CD8+. A expressão do HLA-E não foi associada aos graus de lesões intraepiteliais cervicais. Outros estudos são necessários para melhor compreensão do padrão e da função da expressão das moléculas HLA-E em lesões intraepiteliais cervicais de mulheres infectadas pelo HIV- 1
Among women with HIV / AIDS there is a greater number of cases of persistent HPV infections contributing to an increased risk of developing squamous intraepithelial lesions of the cervix. In addition, abnormal expression of HLA-E molecules can modulate the immune system by binding to the inhibitory (CD94 / NKG2A) or stimulatory (CD94 / NKG2C) receptor NK cells and CD8+ T lymphocytes, decreasing immunovigilance and favoring the evasion of infected cells infected with virus. Due to the lack of studies evaluating the HLA-E molecule in the interaction with HPV, more specifically in HIV-1 infection, this project aimed to evaluate the expression of HLA-E in cervical intraepithelial lesions of infected women or not by HIV- 1, with the infection by HPV. It is a cross-sectional study, which was submitted to immunohistochemical processing the paraffin-embedded cervix tissue of 67 HIV-1 women infected with HIV-1 and 62 uninfected women, all of them with cervical intraepithelial lesion with HPV, which was typified. The expression of HLA-E was quantitatively analyzed as non- expressed, 1% to 30%, 31% to 70% and 71% to 100%. The results showed that the herpes virus infection was higher among HIV + participants (P = 0.005). In immunohistochemical analysis, it became evident that cervical intraepithelial lesions in HIV-1 infected women showed a reduction the expression of HLA-E molecule from 31% to 100% compared to women without HIV-1 infection (P = 0.001) Suggesting that this reduction may be a viral escape mechanism, which leads to a reduction in the presentation of viral peptides to CD8+ T lymphocytes. The expression of HLA-E was not associated with cervical intraepithelial lesions. More studies are need to better understand the pattern and function of HLA-E molecule expression in cervical intraepithelial lesions of infected women by HIV-1
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Ekman, Evelina, and Nicole Karlsson. "Upplevelser av vårdpersonalens bemötande gentemot patienter som lever med HIV, HBV eller HCV : En litteraturstudie." Thesis, Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-83910.

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Introduktion/Bakgrund: Blodsmittor som Humant immunbristvirus [HIV], Hepatit B-virus [HBV] och Hepatit C-virus [HCV] förekommer i många delar av världen. Det finns mycket fördomar om patienter som lever med blodsmitta och patienterna kan uppleva stigmatisering och diskriminering från samhället vilket kan leda till psykisk ohälsa. Syfte: belysa hur patienter som lever med HIV, HBV eller HCV upplever vårdpersonalens bemötande. Metod: En litteraturstudie som följer Polit och Becks (2017) nio steg. PubMed, PsycINFO och Cinahl är de databaser som användes för att söka fram artiklar. 15 artiklar ingick i resultatet, tolv kvalitativa, två mixed-methods och en kvantitativ. Granskningar av artiklarna gjordes med Polit och Becks (2017) granskningsmallar för kvalitativa och kvantitativa studier. Resultat: Fyra teman identifierades till resultatet. Patienterna hade både positiva och negativa erfarenheter av bemötandet från vårdpersonal. De teman som identifierades var Attityder, Nekad vård och vårdpersonalens rädsla för smitta, Bristande sekretess samt Positiva upplevelser av bemötande. Slutsats: Det framkom att flera patienter som lever med blodsmitta hade negativa upplevelser av bemötandet inom hälso- och sjukvården, men de belyser även de positiva erfarenheter de hade av bemötande från vårdpersonal.
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Kaya, Selçuk Cicioğlu Arıdoğan Buket. "Isparta il merkezi kan donörlerinde GBV-C/HGV prevalansı ve HBV ve HCV ile koinfeksiyonunun araştırılması /." Isparta : SDÜ Tıp Fakültesi, 2002. http://tez.sdu.edu.tr/Tezler/TT00093.pdf.

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Books on the topic "HLV"

1

Dirgahayu, Paramasari. Molecular epidemiology database of HIV, HBV, HCV, HDV, HTLV-1/2, and TTV in Central of Java, Indonesia: Final report international research collaboration and international publication. [Surakarta]: Sebelas Maret Univ., 2010.

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Thiemann, Lillian. Double jeopardy: The HIV/HCV co-infection handbook. New York: Community Prescription Service, 1999.

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Human retrovirology: Facts and concepts. Berlin: Springer-Verlag, 1990.

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Schüpbach, Jörg. Human retrovirology: Facts and concepts. Berlin: Springer-Verlag, 1989.

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Schüpbach, Jörg. Human retrovirology: Facts and concepts. Berlin: Springer-Verlag, 1989.

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Glew, Susan Sylvia. HLA Class II antigens and HPV in cervical neoplasia. Manchester: University of Manchester, 1992.

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Scientific Group on Human T-Lymphotropic Virus Tupe-1 (HTLV-1) Infections and Associated Diseases (1992 Kagoshima-shi, Japan). Report: Scientific Group on Human T-Lymphotropic Virus Type-1 (HTLV-1) Infections and Associated Diseases, Kagoshima, Japan, 13-14 October 1992. Manila, Philippines: The Office, 1993.

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Jürgens, Ralf. HIV/AIDS and HCV in prisons: A select annotated bibliography. Ottawa, Ont: International Affairs Directorate, Health Canada, 2005.

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E, Groopman Jerome, and University of California, Los Angeles., eds. Human retroviruses: Proceedings of a Chimertech-UCLA symposium, held at Tamarron, Colorado, February 4-11, 1989. New York: Wiley-Liss, 1990.

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Parks, Peggy J. HPV. San Diego, CA: Daniel A. Leone, Publisher, 2008.

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Book chapters on the topic "HLV"

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Rister, M., M. Suttorp, and U. Siegel. "Granulozytenfunktion bei HlV-infizierten Hämophilie-Patienten." In 18. Hämophilie-Symposion Hamburg 1987, 145–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73589-9_19.

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Evers, S., L. Frohne, D. Reichelt, S. Boeckenholt, and I. W. Husstedt. "Die antivirale Kombinationsbehandlung in der Therapie der HlV-assoziierten Enzephalopathie." In HIV-Infekt, 417–21. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59683-4_74.

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Sporer, B., U. Koedel, F. D. Goebel, and H. W. Pfister. "Nachweis löslichen Fas-Rezeptors und -Liganden im Liquor zerebrospinalis HlV-infizierter Patienten." In HIV-Infekt, 407–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59683-4_72.

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Buxmann, H., M. Depka Prondzinski, I. Scharrer, and M. Behre. "Verlaufsbeobachtung von Sexualhormonen bei HlV-infizierten Patienten mitTestosteronsubstitution bei Hypotestosteronämie." In 26. Hämophilie-Symposion 1995, 422–37. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60418-8_68.

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Vachon, Marie-Louise C., Alicia C. Stivala, and Douglas T. Dieterich. "HIV/HCV and HIV/HBV Co-infections." In Mount Sinai Expert Guides: Hepatology, 78–95. Oxford, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118748626.ch7.

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Gürtler, L. "Infektionsgefährdung von medizinischem Personal und Angehörigen HlV-infizierter Hämophilen Verhütung und Sofortmaßnahmen." In 22. Hämophilie-Symposion Hamburg 1991, 56–64. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77881-0_8.

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Stoll, M., R. E. Schmidt, S. Staszewski, C. Katlama, R. L. Murphy, R. van Leeuwen, S. Gruijs, J. P. Sommadossi, and J. Lange. "ATLANTIC: Unverblindete, randomisierte prospektive Studie zum Vergleich konvergenter antiretroviraler Dreifachkombinationen mit einer Protease-lnhibitor-haltigen (divergenten) Standardtherapie nicht vorbehandelter HlV-lnfizierter." In HIV-Infekt, 230–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59683-4_39.

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Coffin, Carla S., and Norah A. Terrault. "Treatment of HCV, HDV, or HIV Coinfection." In Hepatitis B Virus and Liver Disease, 239–62. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4843-2_13.

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Zhou, Kali, and Norah A. Terrault. "Treatment of HCV, HDV, or HIV Coinfections." In Hepatitis B Virus and Liver Disease, 339–73. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3615-8_15.

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Hu, Jianming, Kuancheng Liu, and Jun Luo. "HIV–HBV and HIV–HCV Coinfection and Liver Cancer Development." In Cancer Treatment and Research, 231–50. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-03502-0_9.

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Conference papers on the topic "HLV"

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Kanotra, Rahul, Mohamed Aboumalwa, Chellakat Joe-Joe, Sajith Nair, and Vijoy Koottungal. "Dynamics of Heavy Deck Lift-Off From Transportation Barge." In ASME 2012 31st International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/omae2012-83458.

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The size of present day offshore topsides are growing rapidly, with large capacity, complex modules being transported and lifted offshore. This increase in size results in offshore lift weights which are near crane capacity of HLVs (heavy lift vessels). The offshore installation operation involves lift-off of heavy modules from a transportation barge moored perpendicular to the stern of the HLV. Previous experiences with lift analyses indicate that most significant hook load occurs while the module is being lifted off the transportation barge. This can be attributed to the fact that the crane vessel, topside and the transportation barge are all dynamically coupled together and during the “lift-off” condition the module experiences upward and downward impulsive forces from the transportation barge, which in turn increase the apparent weight of the module and hence the hook loads. This paper studies the dynamics of heavy deck lift-off from the transportation barge, when the sea fastening from the module has been removed and all three bodies (transportation barge, HLV and Module) are mechanically coupled through slings, lashings and fenders. The effect of various crane line pretensions, wave, current and wind has been investigated and the resulting DAFs (dynamic amplification factors) of the hook loads have been compared. The effect of wind and current on the lift operation has also been investigated. The “lift in air” case has been studied and compared with the “lift off” case. Multi Operational Structural Engineering Simulator (MOSES) has been used to carry out 3D time domain analysis of lift off and lift in air cases. McDermott’s HLV, 300 class transport barge and a topside weight of 1,500MT have been analyzed for the study.
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Wever, Roger, and Pascal Hendriks. "Deepwater SCR Installation With the HLV Thialf." In ASME 2009 28th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/omae2009-79966.

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Deep water oil and gas exploration make regularly use of Steel Catenary Risers (SCR) to transfer oil and gas from wellheads to host. From the host the oil and/or gas is transferred (after processing) to subsea pipelines by SCRs. Regular practice is to have the SCRs pre-laid on the seabed prior to host installation. Last Summer Heerema Marine Contractors utilized the Heavy Lift Vessel (HLV) Thialf to recover and install 8 pre-laid SCRs. The HLV Thialf also installed the Tension Leg Platform host. The SCRs: two 6″, two 8″, two 10″ SCRs, a 12″ Export Gas SCR, a 16″ Export Oil SCR were pre-laid in multiple crossings pattern around the TLP. The A&R winch was used to recover the SCRs from approximately 1,350 m waterdepth followed by SCR hand-over to one of the Thialf’s heavy lift cranes for installation to the host. This paper will focus on the SCR recovery and hang-off operation. Several topics will be discussed: the pre-lay, subsea hand-over and the large vessel rotation performed for SCR installation. Additionally, first time use items such as the welded eye connection, open top container for pull-in wire storage and the newly designed hydraulic shackle will also be presented.
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3

Alvaer, P. O., and O. Lundby. "Hlv Transports – DNV Guidelines For Calculations of Cribbing Friction." In Marine Heavy Transport & Lift. RINA, 2005. http://dx.doi.org/10.3940/rina.hea.2005.06.

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4

Huang, Panxing, Yuanbei Gu, Changzhu Wei, and Naigang Cui. "Reconfigurable control system design based on control allocation for HLV." In 2015 27th Chinese Control and Decision Conference (CCDC). IEEE, 2015. http://dx.doi.org/10.1109/ccdc.2015.7162544.

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5

Stephan, W., H. Dichtelmüller, A. M. Prince, L. Gürtler, and F. Deinhardt. "INACTIVATION OF HEPATITIS VIRUSES AND HIV IN PLASMA AND PLASMA DERIVATIVES BY COMBINED TREATMENTWITH β-PR0PI0LACT0NE/UV-IRRADIATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644147.

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A combined treatment of plasma andplasma derivatives by β-Propiolactone (β-PL) /UV-irradiation is inuse at Biotest for the preparation ofthe virus safe serum preserve Bisekd® and coagulation factor concentrates.The efficacy of this sterilization procedure has been demonstrated for HAV(> 8.2 log10), HBV ( 7.0 log10) and HNANB (> 4.5 log10). As HIV has become a major problem tne inactivation of HIV by β-PL/UV in human plasma was tested. Pooled human plasma was spiked with 104.2 infectious units per ml of the Gallo strain of HIV/ HTLV-III and sterilized with 0.25 % β-PL, 60 min at pH 7.2 and subsequently UV-irradiated (4 × 20 W). After treatment with β-PL alone orβ-PL/UV no infectious HIV was detectable by reverse transcriptase assay in inoculated H-9 cultures after 14 days of cultivation (> 4.2 log10 inactivation). When the virucidal efficacy of ft-PL and UV was tested separately, β-PL inactivated > 3.5 log10, UV-irradiation another 2.5 log10 of HIV, as demonstrated by immunofluorescence tests in H-9 cultures 27 daysafter inoculation.When cryoprecipitate/F VUI-concentrate was sterilized by ft-PL and UV, > 4.5 log10 of HIV were inactivated by UV and > 3.5 log10 by α-PL. The results indicate, that the combined treatment by β-PL/UV inactivates all potentialtiters of HIV, which can be expected inscreened and pooled human plasma orcryoprecipitate, used for the preparation of virus safe plasma derivatives.
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Schmidbauer, C., D. Chromy, V. Schmidbauer, T. Bucsics, P. Schwabl, M. Mandorfer, B. Scheiner, et al. "Epidemiological trends of HBV and HDV coinfection among HIV+ patients." In 51. Jahrestagung & 29. Fortbildungskurs der Österreichischen Gesellschaft für Gastroenterologie & Hepatologie (ÖGGH). Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1654658.

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7

Darvishian, Maryam, Carmine Rossi, Stanley Wong, Amanda Yu, Jason Wong, Jane Buxton, Mark Gilbert, et al. "P386 Cancer risk among people with HIV, HBV and/or HCV infections." In Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/sextrans-2019-sti.481.

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8

Barrett, P. N., G. Wöber, J. Eibl, and F. Dorner. "EFFICIENCY OF STEAM TREATMENT PROCEDURES USED FOR VIRUS INACTIVATION IN HUMAN COAGULATION FACTORS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644152.

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The transmission of viral agents from blood products derived from humanplasma has long been a serious healthproblem for the recipients. The majoragents involved are HBV, nonA nonB, Delta agent and HIV (LAV/HTLV-III). Wehave attempted to design product-specific viral inactivation procedures toprevent such transmission in blood products. Experiments were carried out with HIV, which is the only one of the above viruses which can be propagated and titrated in cell culture, and with a wide range of model viruses. High titre virus was added to blood products, and they were then subjected to different virus inactivation procedures.Heat treatment was carried out in aqueous solution with and without protein-stabilising agents, and it was demonstrated that such agents added toprevent loss of biological activity of blood products also resulted in a stabilisation of contaminating viruses.Therefore steam treatment inactivation procedures have been developed without the addition of such agents. Steam pressure, temperature and time of inactivation are the main variablesand these can be altered for each product to achieve an optimal balance between the degree of virus inactivation and retention of biological activity.It has been shown that each of thedifferent product-specific treatment procedures has a high HIV inactivation capacity.Studies with various model virusesalso demonstrated that the efficiencyof these procedures could be furtherimproved if necessary by altering various parameters such as steam pressure.
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Kumar, Anoop, Inderjit Singh Yadav, Rupinder Sekhon, Dwaipayan Bharadwaj, and Mausumi Bharadwaj. "Identification of T- and B-cell epitopes in HPV-16 E7 gene isolated from cervical cancer patients." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685256.

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Introduction: In India, cervical cancer is the most common cancer among females. Persistence infection with high risk human papillomaviruses (HR-HPV) is an etiological agent for cervical cancer development, especially HPV-16 is found to be exclusively high in cervical cancer cases in Indian population. The continuous expression and transforming ability of HPV E7 helps in progression of cervical cancer and other HPV related disease, which make E7 as a suitable targets for the development of therapeutic vaccines. Objectives: Identification of T-& B-cell epitopes HPV-16 E7 gene isolated from in cervical cancer patients. Materials and Methods: A total of 80 cervical cancer tissue biopsies were collected and processed for DNA extraction, HPV diagnosis and genotyping. E7 gene of HPV-16 positive samples were amplified and sequenced. Epitopes in E7 gene sequence were predicted by online freely available tools. Results: In the present study we got 72 samples (90%) were positive for HPV and out of which 68 samples (94.4%) were positive for the HPV-16. HPV-16 positive samples were sequenced and translated. IEDB server was used for epitope analysis; 12 potent epitopes for the MHC-I alleles were identified in isolated E7 gene of HPV-16. The most potent epitopes were MHGDTPTLHEYM for HLA-C*07:01; LLMGTLGIVCPI for HLA-A*02:01 and MHGDTPTLHEYML for HLA-C*07:01; having percentile rank 0.2 for all three and antigencity score of 0.20011, 0.15358 and 0.10735, respectively. Conclusion: This is an effective strategy to design immuno-therapeutics and therapeutic vaccine against HPV using E7 as target. These findings will be helpful in the development of effective vaccine for particular geographical region.
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Yarraguntla, Nireekshith, Naveena Tirumala, Syed Shameem, and K. srinivasa rao. "Detection of Hepatitis viruses (HBV, HAV, HCV) in serum using MEMS based Bio-Sensor." In 2018 Second International Conference on Computing Methodologies and Communication (ICCMC). IEEE, 2018. http://dx.doi.org/10.1109/iccmc.2018.8487679.

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Reports on the topic "HLV"

1

Becker-Khaleel, B., and K. Schlick. 324 Building REC and HLV Tank Closure Plan. Office of Scientific and Technical Information (OSTI), December 1995. http://dx.doi.org/10.2172/204127.

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2

Bolognesi, Dani P. Biological Significance of the Immune Response to HTLV-III/HAV. Fort Belvoir, VA: Defense Technical Information Center, December 1990. http://dx.doi.org/10.21236/ada234622.

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Mensch, Barbara, and Erica Soler-Hampejsek. Characteristics associated with HIV and HSV-2 among adolescents in Malawi. Population Council, 2017. http://dx.doi.org/10.31899/hiv6.1007.

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Mensch, Barbara, and Erica Soler-Hampejsek. Rates of HIV and HSV-2 among young people in Machinga, Malawi. Population Council, 2017. http://dx.doi.org/10.31899/hiv6.1027.

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Smith, Lynette M., Nicholas A. Hein, and Danstan S. Bagenda. Cash transfers and HIV/HSV-2 prevalence: a replication of a cluster randomized trial in Malawi. International Initiative for Impact Evaluation (3ie), October 2017. http://dx.doi.org/10.23846/rps0012.

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Yu, Fang, Nicholas A. Hein, and Danstan S. Bagenda. Preventing HIV and HSV-2 through improving knowledge and attitudes: a replication study of a multicomponent intervention in Zimbabwe. International Initiative for Impact Evaluation (3ie), March 2018. http://dx.doi.org/10.23846/rps0016.

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Skone, Timothy J. HLW Disposition. Office of Scientific and Technical Information (OSTI), August 2011. http://dx.doi.org/10.2172/1509389.

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Pinter, Abraham. HIV Vaccines Based on Novel MULV-HIV Fusion Proteins. Fort Belvoir, VA: Defense Technical Information Center, July 1999. http://dx.doi.org/10.21236/ada373677.

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Matyas, Josef, Adam R. Huckleberry, Carmen P. Rodriguez, Jesse B. Lang, Antionette T. Owen, and Albert A. Kruger. HLW Glass Studies: Development of Crystal-Tolerant HLW Glasses. Office of Scientific and Technical Information (OSTI), April 2012. http://dx.doi.org/10.2172/1062511.

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Bingamon, Brian Michael. HIV Mosaic Vaccine. Office of Scientific and Technical Information (OSTI), December 2019. http://dx.doi.org/10.2172/1581247.

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