Academic literature on the topic 'Hmotnostní spectrometrie'

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Journal articles on the topic "Hmotnostní spectrometrie"

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Turay, Jozef. "Predpoveď kardiovaskulárneho rizika pomocou hmotnostnej spektrometrie." Laboratórna Diagnostika XXIX, no. 1/2024 (2024): 76–80. https://doi.org/10.5281/zenodo.12532065.

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<strong>S&uacute;hrn</strong> Lipidomika je vedn&yacute; obor, ktor&yacute; sa zaober&aacute; &scaron;t&uacute;diom biochemick&yacute;ch dr&aacute;h lipidov v biologick&yacute;ch syst&eacute;moch. Ide o nov&uacute; sub&scaron;pecializ&aacute;ciu klinickej bioch&eacute;mie, ktor&aacute; je podložen&aacute; v&yacute;sledkami najm&auml; hmotnostnej spektrometrie. V&nbsp;poslednom desaťroč&iacute; sa nahromadili d&ocirc;kazy o&nbsp;&uacute;lohe ceramidov a&nbsp;fosfolipidov ako možn&yacute;ch&nbsp; medi&aacute;torov aterokler&oacute;zou podmienen&yacute;ch kardiovaskul&aacute;rnych ochoren&iacute;
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Friedecký, D., and K. Lemr. "Introduction to mass spectrometry." Klinická biochemie a metabolismus 20, no. 3 (2012): 152–57. https://doi.org/10.61568/kbm.2012.028.

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Friedecký, D., and K. Lemr. "Mass spectrometry - source of analytical information." Klinická biochemie a metabolismus 20, no. 4 (2012): 210–15. https://doi.org/10.61568/kbm.2012.040.

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Vacek, J. "Mass spectrometry of intact tissue and its application in diagnostics." Klinická biochemie a metabolismus 14, no. 4 (2006): 194–95. https://doi.org/10.61568/kbm.2006.028.

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Chrastina, P., S. Šťastná, H. Myšková, M. Košařová, M. Elleder, and J. Zeman. "Newborn Screening of Inherited Metabolic Disorders by Tandem Mass Spectrometry." Klinická biochemie a metabolismus 13, no. 2 (2005): 77–80. https://doi.org/10.61568/kbm.2005.013.

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Humplíková, S., J. Minář, M. Kučerová, M. Radina, and D. Valík. "Determination of total homocysteine level in plasma by liquid chromatography and tandem mass spectrometry." Klinická biochemie a metabolismus 15, no. 1 (2007): 31–34. https://doi.org/10.61568/kbm.2007.008.

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Demeshko, Olga V., Elena V. Krivoruchko, Victoria A. Samoilova, and Svetlana V. Romanova. "Gas chromatography-mass spectrometry study of the root and herb of Smallanthus sonchifolius." Česká a slovenská farmacie 67, no. 4 (2018): 160–63. https://doi.org/10.36290/csf.2018.023.

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Greplová, K., R. Pilný, L. Dubská, et al. "SELDI TOF mass spectrometry in cancer research - pilot methodological data and possible clinical applications." Klinická biochemie a metabolismus 16, no. 3 (2008): 189–93. https://doi.org/10.61568/kbm.2008.035.

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LAŠTOVIČKOVÁ, Markéta, and Janette BOBÁĽOVÁ. "Determination of important barley (Hordeum vulgare) proteins by the separation methods and mass spectrometry." Kvasny Prumysl 56, no. 2 (2010): 79–82. http://dx.doi.org/10.18832/kp2010009.

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Klapková, E., R. Uřinovská, and R. Průša. "The influence of matrix effects on high performance liquid chromatography-mass spectrometry methods development and validation." Klinická biochemie a metabolismus 19, no. 1 (2011): 5–8. https://doi.org/10.61568/kbm.2011.002.

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Dissertations / Theses on the topic "Hmotnostní spectrometrie"

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Navrátilová, Romana. "Strukturní studium karboranů s využitím hmotnostní spektrometrie." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2009. http://www.nusl.cz/ntk/nusl-216532.

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Boron cluster compounds are substances clearly synthetic, which don't exist outdoors. This group covers boranes, heteroboranes and their derivatives. They are synthesized and examined mostly for their extraordinary structural and bonding properties. Their study also brought many remarkable findings and even allowed practical use of these compounds in science and technology. This thesis is focused on the application of mass spectrometry for the identification of boranes and heteroboranes and on the study of their fragmentation mechanisms using tandem mass spectrometry on spherical ion trap.
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Beneš, Ondřej. "Zpracování a visualizace hmotnostních spekter." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2014. http://www.nusl.cz/ntk/nusl-235426.

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One of new techniques in the field of analytical chemistry, which has more and more practical use, is mass spectrometry imaging. With its ability to record representation of substances in samples during the tissue analyze arise problem with a lot of output data which needs to be handled programmatically. The goal of this work is to create an software for processing and visualization data of new standard imzML. As a part of the work, the field of mass spectrometry, primarily MALDI TOF mass spectrometry, is briefly introduced. There are also introduced some methods for mass spectrometry data pre
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Valla, Martin. "Systém pro zpracovaní skóre z metod identifikace proteinů v tandemové hmotnostní spektrometrii." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2008. http://www.nusl.cz/ntk/nusl-217552.

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The goal of my diploma thesis was finding a suitable method for unifying score values from various protein identification search tools in MS/MS mass spectrometry into one single score value. Data coming from the output of mass spectrometer are processed in two independent search tools Mascot and X!Tandem. These were selected especially for their wide usage in proteomic labs. Both results are evaluated through newly designed function and unified by single valued score clearly identifying found proteins. Newly designed scoring value is called Matascore and function producing this score was imple
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Čumová, Martina. "Využití hmotnostní spektrometrie ke stanovení markerů oxidativního stresu a mykotoxinů." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2015. http://www.nusl.cz/ntk/nusl-233402.

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The first topic presented in the dissertation thesis is determination of isoprostanes as markers of oxidative stress and other compounds affected by presence of oxidative stress. Isoprostanes iPF2-III, iPF2-VI, iPF2-VI, astaxanthin and polyunsaturated fatty acids (PUFA), especially arachidonic acid (AA) were monitored in Atlantic salmon eggs (Salmo salar). Methods for the determination of these compounds have been developed and optimized using chromatographic separation coupled to conventional or mass spectrometric detection. Freshly laid eggs, eyed embryos and non-viable eggs were used to tes
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Čumová, Martina. "Využití separačních metod s hmotnostní detekcí pro studium degradačních produktů nových polymerních materiálů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2009. http://www.nusl.cz/ntk/nusl-216540.

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Synthetic polymer materials have been a part of human life since the 20th century. A variety of their use had resulted in a growing demand for their mass production, which then led to their increasing accumulation at waste dumps. After their deposition, these materials are exposed to many environmental factors causing their decomposition and subsequent release of the degradation products into the environment. This thesis is focused on the analysis of the photodegradation products from synthetic polymer materials and particularly polyurethane foams modified with the biodegradable fillers. One d
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Žvaková, Veronika. "Detailní charakterizace pyrolýzního oleje pomocí separačních technik a hmotnostní spektrometrie." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-316220.

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The aim of this work is detailed characterization of pyrolysis oil by advanced analytical separation methods and mass spectrometry. During the pyrolysis process decomposition of complex organic material take place in the presence of high temperatures and the absence of oxygen. Condensable part of vapours and aerosols forms viscous liquid called pyrolysis oil which is a complex mixture of large amount of compounds. In this work samples from microwave pyrolysis of woodchips and sewage sludge from wastewater treatment plant Brno-Modřice were analysed. Samples were provided by Bionic Laboratories
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Jurasová, Lenka. "Stanovení vybraných hormonálních přípravků pomocí kapalinové chromatografie s hmotnostním detektorem." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-216864.

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This master’s thesis is focused on optimizing of the analytical method for the determination of selected drugs - estrone, estradiole, ethynylestradiol, estriole, diethylstilestrole, norethindrone, mestranole and progestrone in wastewater using liquid chromatography with mass spectrometry (LC/MS). Solid phase extraction (SPE) using Oasis HLB cartridges was chosen extraction method Different mobile phase, temperature, flow rates and mobil phase gradient were during the process of optimization. Samples of the wastewater were collectedat the inflow and outlow of the wastewater treatment plant in B
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Kuba, Pavel. "Zpracování a vizualizace dat z hmotnostního spektrometru typu TOF-MALDI." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230019.

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This thesis describes the development of control applications for the deposition machine and mass spectrometer. Thesis describes operation principles of both devices and their hardware specifications. Thesis also describes the design of developed applications. Functionality was tested on series of real measurements.
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Trčková, Marie. "Využití metody LC/MS k analýze vybraných přírodních fyziologicky aktivních látek." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2008. http://www.nusl.cz/ntk/nusl-216232.

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Presented work is focused on application of combined instrumental method RP-HPLC/ESI-MS in analysis of several groups of natural compounds with positive physiological activities. Especially some antioxidants were studied in commonly and abundantly consumed food. Moreover some other substances than standard compounds were observed in complex dies. In conclusion the HPLC/ESI-MS method is comparatively advantageous in phenolic analysis, while another type of ionisation would be used in case of carotenoid compound.
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Obalil, Jiří. "Miniaturizované techniky pro analýzu průmyslových kvasinek." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2008. http://www.nusl.cz/ntk/nusl-216334.

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Carotenoids are natural pigments that have antioxidation and antimutagenic abilities. They are produced with the help of new technological methods. For example, carotenoid yeast Rhodotorula glutinis produces -carotene with the yield of up to 6 – 10 mg/g of the dry substance. The method of the mass spectrometry with the nanoelectrospray in the positive mode was optimized for the determination of -carotene, lycopene and astaxanthin in this project. Ionizing voltage of 4 kV and the sample flow rate of 15 – 80 nl/min through the spray silica fused capillary with the internal diameter of 25 µm were
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