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Journal articles on the topic 'Hobs'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Pelusi, Letizia, Domitilla Mandatori, Nadia Di Pietrantonio та ін. "Estrogen Receptor 1 (ESR1) and the Wnt/β-Catenin Pathway Mediate the Effect of the Coumarin Derivative Umbelliferon on Bone Mineralization". Nutrients 14, № 15 (2022): 3209. http://dx.doi.org/10.3390/nu14153209.

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Bone physiology is regulated by osteoblast and osteoclast activities, both involved in the bone remodeling process, through deposition and resorption mechanisms, respectively. The imbalance between these two phenomena contributes to the onset of bone diseases. Among these, osteoporosis is the most common metabolic bone disorder. The therapies currently used for its treatment include antiresorptive and anabolic agents associated with side effects. Therefore, alternative therapeutic approaches, including natural molecules such as coumarin and their derivatives, have recently shown positive resul

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Liu, Ling-juan, Li-qun Liu, Tao Bo, et al. "Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway." International Journal of Endocrinology 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/786574.

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Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts (hOBs) apoptosis is still unclear. In this study, we detected the function of puerarin on serum-free-induced cell apoptosis using ELISA and TUNEL arrays and then found that the mortality of hOBs was significantly decreased after exposure to 10−10–10−6 M puerarin and reached the ma

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3

Grundberg, Elin, Helena Brändström, Kevin C. L. Lam, et al. "Systematic assessment of the human osteoblast transcriptome in resting and induced primary cells." Physiological Genomics 33, no. 3 (2008): 301–11. http://dx.doi.org/10.1152/physiolgenomics.00028.2008.

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Osteoblasts are key players in bone remodeling. The accessibility of human primary osteoblast-like cells (HObs) from bone explants makes them a lucrative model for studying molecular physiology of bone turnover, for discovering novel anabolic therapeutics, and for mesenchymal cell biology in general. Relatively little is known about resting and dynamic expression profiles of HObs, and to date no studies have been conducted to systematically assess the osteoblast transcriptome. The aim of this study was to characterize HObs and investigate signaling cascades and gene networks with genomewide ex

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Xuhui Zhang, _Kang Long, Tao Tan, Sijia Li, and LianLian Tan. "Study on rock-breaking characteristics of constant section and spherical tooth hob with the aid of slot produced by water jet." Mining Science 31 (2024): 61–79. http://dx.doi.org/10.37190/msc243104.

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In order to analyze and compare the rock-breaking characteristics of constant section hob (CS hob) and spherical tooth hob (ST hob) with the aid of slot produced by water jet, a linear cutting models of granite using two types of hobs under the slot conditions were established using the finite element method. The cutting forces, rock-breaking states, and specific energy consumption of hobs were calculated. The research results revealed that during the cutting process, both types of hobs can induce surface and internal tensile cracks in the rock. There exists a critical cutting width for each t

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Crispi, Vassili, William Bolton, Rebecca Town, and Ian Anderson. "Effect of neurosurgical high observation beds (HOBs) on service provision: a single-centre experience and cost analysis." BMJ Open 13, no. 7 (2023): e073461. http://dx.doi.org/10.1136/bmjopen-2023-073461.

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ObjectiveTo evaluate the effect of level 1, high observation beds (HOBs) compared with high dependency unit (HDU) and neurosurgical intensive care unit (NICU) admission on service provision, such as cancelled operations, and healthcare costs.MethodsA retrospective, observational, single-centre cross-sectional study at a single, large UK neurosurgical centre. All adult patients admitted to neurosurgical HOBs between December 2021 and July 2022 were included. The list of cancelled procedures was collected from 2019 to 2022. To evaluate the impact of admission of eligible patients to HOBs, the to

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Karadag, Abdullah, Min Zhou та Peter I. Croucher. "ADAM-9 (MDC-9/meltrin-γ), a member of the adisintegrin and metalloproteinase family, regulates myeloma-cell–induced interleukin-6 production in osteoblasts by direct interaction with the αvβ5 integrin". Blood 107, № 8 (2006): 3271–78. http://dx.doi.org/10.1182/blood-2005-09-3830.

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Abstract ADAM-9, a member of the adisintegrin and metalloproteinase family, contains both metalloproteinase and disintegrin domains. Myeloma cell lines express ADAM-9; however, its function and role in the pathophysiology of multiple myeloma is unknown. The aim of this study was to establish whether primary myeloma cells express ADAM-9, whether ADAM-9 regulates IL-6 production in human osteoblasts (hOBs), whether ADAM-9 interacts with specific integrin heterodimers, and the identity of downstream signaling pathways. Primary myeloma cells demonstrated increased expression of ADAM-9 (P < .01)

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Solar, Maja. "SPINOZA KAO ANTI-HOBS." ARHE 10, no. 19 (2015): 7. http://dx.doi.org/10.19090/arhe.2013.19.7-25.

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Rad prati nekoliko linija kojima se Spinoza misli prevashodno kao anti-Hobs, u teorijsko-političkom smislu. Ključne linije kojima se to pokazuje su: ravan imanencije i transcendencije, ravan odnošenja afekta straha i slobode, ravan veze individualiteta i kolektiviteta, te, posebno, ravan odnošenja koncepta naroda i mnoštva. Dok se Hobsova misao pokazuje krucijalnom za ideje individualizma i liberalne tradicije, Spinoza se pokazuje kao mislilac kolektiviteta, mnoštva, i time kao inspiracija materijalističkim čitanjima.

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8

Kirov, Vanio. "Design of spiroid hobs." Journal of Materials Processing Technology 88, no. 1-3 (1999): 208–15. http://dx.doi.org/10.1016/s0924-0136(98)00397-5.

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9

Wu, Jie, and Jia Quan Wang. "Study on Design Method of the Double Arc Gear Hobs." Advanced Materials Research 823 (October 2013): 257–60. http://dx.doi.org/10.4028/www.scientific.net/amr.823.257.

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This article find that one of the effecting the double circular arc gear s running performance is the double circular arc gear tooth profile precision, through analysis to the running-in properties of double arc gear. The problems about tooth profile precision of gear hobs caused by the current profiling theory and approximate design method of gear hobs are analyzed. In the design of circular arc gear hob, use the space engagement theory, can eliminating the tooth error. Acquiring the equation of hobs basic of worm tooth surface by analytical and calculation that the establishment of basic gea

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10

AINOURA, Masato, and Isao SAKURAGI. "The damage of carbide hobs." JSME international journal. Ser. 3, Vibration, control engineering, engineering for industry 31, no. 1 (1988): 121–28. http://dx.doi.org/10.1299/jsmec1988.31.121.

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11

Piotrowski, Andrzej, Rafał Gołębski, and Piotr Boral. "Geometrical Analysis of Composite Hobs." Transactions of FAMENA 44, no. 1 (2020): 43–54. http://dx.doi.org/10.21278/tof.44104.

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12

AINOURA, Masato, and Isao SAKURAGI. "The damage of carbide hobs." Transactions of the Japan Society of Mechanical Engineers Series C 53, no. 493 (1987): 2008–16. http://dx.doi.org/10.1299/kikaic.53.2008.

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Sandler, Alexander, and Sergey Lagutin. "Technique of tooth relieving of worm hobs for cutting Novikov gears with double lines of action." MATEC Web of Conferences 317 (2020): 05001. http://dx.doi.org/10.1051/matecconf/202031705001.

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Worm hobs for cutting Novikov gears have the profile of a generating worm, which varies not only in a radius, but also in a sign of curvature. A technique for relieving tooth flanks of these hobs by disk grinding wheel is developed. It allows for bringing together grinding and ground profiles in an axial section of the generating worm as close as possible. A method for calculating setting-ups and profile coordinates of the grinding wheel is given for real production conditions.

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Caliogna, Laura, Valentina Bina, Alice Maria Brancato, et al. "The Role of PEMFs on Bone Healing: An In Vitro Study." International Journal of Molecular Sciences 23, no. 22 (2022): 14298. http://dx.doi.org/10.3390/ijms232214298.

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Bone responses to pulsed electromagnetic fields (PEMFs) have been extensively studied by using devices that expose bone cells to PEMFs to stimulate extracellular matrix (ECM) synthesis for bone and cartilage repair. The aim of this work was to highlight in which bone healing phase PEMFs exert their action. Specifically, we evaluated the effects of PEMFs both on human adipose mesenchymal stem cells (hASCs) and on primary human osteoblasts (hOBs) by testing gene and protein expression of early bone markers (on hASCs) and the synthesis of late bone-specific proteins (on hOBs) as markers of bone r

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Nieszporek, Tadeusz, and Andrzej Piotrowski. "Enhancing the Accuracy of Composite Hobs." Procedia Engineering 177 (2017): 155–61. http://dx.doi.org/10.1016/j.proeng.2017.02.208.

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Quent, Verena M. C., Christina Theodoropoulos, Dietmar W. Hutmacher, and Johannes C. Reichert. "Differential osteogenicity of multiple donor-derived human mesenchymal stem cells and osteoblasts in monolayer, scaffold-based 3D culture and in vivo." Biomedical Engineering / Biomedizinische Technik 61, no. 3 (2016): 253–66. http://dx.doi.org/10.1515/bmt-2014-0159.

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Abstract We set out to compare the osteogenicity of human mesenchymal stem (hMSCs) and osteoblasts (hOBs). Upon osteogenic induction in monolayer, hMSCs showed superior matrix mineralization expressing characteristic bone-related genes. For scaffold cultures, both cell types presented spindle-shaped, osteoblast-like morphologies forming a dense, interconnected network of high viability. On the scaffolds, hOBs proliferated faster. A general upregulation of parathyroid hormone-related protein (PTHrP), osteoprotegrin (OPG), receptor activator of NF-κB ligand (RANKL), sclerostin (SOST), and dentin

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D’Amico, Emira, Tania Vanessa Pierfelice, Rosa Amoroso, et al. "Emerging Effects of Resveratrol Derivatives in Cells Involved in Oral Wound Healing: A Preliminary Study." International Journal of Molecular Sciences 24, no. 4 (2023): 3276. http://dx.doi.org/10.3390/ijms24043276.

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Recently, there has been an increasing interest in finding new approaches to manage oral wound healing. Although resveratrol (RSV) exhibited many biological properties, such as antioxidant and anti-inflammatory activities, its use as a drug is limited by unfavorable bioavailability. This study aimed to investigate a series of RSV derivatives (1a–j) with better pharmacokinetic profiles. At first, their cytocompatibility at different concentrations was tested on gingival fibroblasts (HGFs). Among them, derivatives 1d and 1h significantly increased cell viability compared to the reference compoun

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Petrini, Morena, Emira D’Amico, Tania Vanessa Pierfelice, et al. "Photodynamic Therapy with Aminolevulinic Acid Enhances the Cellular Activity of Cells Cultured on Porcine Acellular Dermal Matrix Membranes Used in Periodontology." Gels 9, no. 7 (2023): 584. http://dx.doi.org/10.3390/gels9070584.

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This study aims to test a photodynamic protocol based on a gel containing aminolevulinic acid followed by red-LED (ALAD-PDT) irradiation on human gingival fibroblasts (hGFs) and osteoblasts (hOBs) cultured on a porcine acellular dermal matrix membrane (PADMM). In the previous literature, ALAD-PDT showed solid antibacterial activity and proliferative induction on HGFs cultured on plates and HOBs cultured on a cortical lamina. PADMMs are used in dentistry and periodontology to treat gingival recessions and to increase the tissue thickness in the case of a thin biotype without the risks or postop

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Zhu, Li Da, Ji Jiang Wu, Chun Guang Liu, Wen Wen Liu, and Shuai Xu. "Research on Simulation Process of Rock Broken by TBM Hob." Advanced Materials Research 712-715 (June 2013): 633–36. http://dx.doi.org/10.4028/www.scientific.net/amr.712-715.633.

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The rock broken process was simulated by using finite element method based on the hob broken rock mechanism. The rock broken shape was analyzed by adjustment numbers of hobs and angles of hob. The destruction of rock was the presence of both compressive failure and shear failure. The main destruction of rock was compressive failure with single hob. The main destruction of rock was shear failure with multiple hobs. It could be found that the main destruction of hard and brittle rock was shear failure but shear failure of softer rock was relatively small through rock breaking process of three ho

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20

Gao, Yan’e, Bingkui Chen, and Dong Liang. "Mathematical models of hobs for conjugate-curve gears having three contact points." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 229, no. 13 (2014): 2402–11. http://dx.doi.org/10.1177/0954406214558674.

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Conjugate-curve gears are the gears which are point contact and the locus curves of the contact points are conjugate curves. The contact pattern of the conjugate-curve gear tooth surfaces are convex to concave, which reduces the contact stress of the tooth surfaces due to the small value of the relative curvature radius at the contact point. The tubular tooth surfaces of the conjugate-curve gears have one pair of conjugate curves. To decrease the running-in time and increase the load capacity, the conjugate-curve gears having three pairs of conjugate curves are designed. The contact stress of

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21

Corradini, Matteo, Marta Checchi, Marzia Ferretti, Francesco Cavani, Carla Palumbo, and Vincenza Rita Lo Vasco. "Endoplasmic reticulum localization of phosphoinositide specific phospholipase C enzymes in U73122 cultured human osteoblasts." AIMS Biophysics 10, no. 1 (2023): 25–49. http://dx.doi.org/10.3934/biophy.2023004.

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<abstract> <p>Different signal transduction pathways contribute to the differentiation and metabolic activities of osteoblasts, with special regard to the calcium-related pathway of phosphoinositide specific phospholipase C (PLC) enzyme family. PLC enzymes were demonstrated to be involved in the differentiation of osteoblasts and differently localize in the nucleus, cytoplasm or both depending on the isoform. The amino-steroid molecule U-73122 inhibits the enzymes belonging to the PLC family. In addition to the temporary block of the enzymatic activity, U-73122 promotes off-target

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22

Kyyak, Solomiya, Andreas Pabst, Diana Heimes, and Peer W. Kämmerer. "The Influence of Hyaluronic Acid Biofunctionalization of a Bovine Bone Substitute on Osteoblast Activity In Vitro." Materials 14, no. 11 (2021): 2885. http://dx.doi.org/10.3390/ma14112885.

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Bovine bone substitute materials (BSMs) are used for oral bone regeneration. The objective was to analyze the influence of BSM biofunctionalization via hyaluronic acid (HA) on human osteoblasts (HOBs). BSMs with ± HA were incubated with HOBs including HOBs alone as a negative control. On days 3, 7 and 10, cell viability, migration and proliferation were analyzed by fluorescence staining, scratch wound assay and MTT assay. On days 3, 7 and 10, an increased cell viability was demonstrated for BSM+ compared with BSM− and the control (each p ≤ 0.05). The cell migration was enhanced for BSM+ compar

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23

Liu, Xi Ling, Xiang Hu, Wei Xin Cai, Weijia William Lu, and Li Wu Zheng. "Effect of Granulocyte-Colony Stimulating Factor on Endothelial Cells and Osteoblasts." BioMed Research International 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/8485721.

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Objectives. Some animal studies showed that granulocyte-colony stimulating factor (G-CSF) provides beneficial environment for bone healing. It has been well documented that endothelial cells and osteoblasts play critical roles in multiple phases of bone healing. However, the biological effects of G-CSF on these cells remain controversial. This study aimed to investigate the influence of G-CSF at various concentrations on endothelial cells and osteoblasts.Materials and Methods. Human umbilical vein endothelial cells (HUVECs) and human osteoblasts (hOBs) were treated with G-CSF at 1000, 100, 10,

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Heithaus, M. R., and R. H. Laushman. "Genetic variation and conservation of stream fishes: influence of ecology, life history, and water quality." Canadian Journal of Fisheries and Aquatic Sciences 54, no. 8 (1997): 1822–36. http://dx.doi.org/10.1139/f97-083.

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Three stream-dwelling fish species were used to investigate effects of ecology, life history, and water quality on genetic variation. We sampled Etheostoma caeruleum, E. blennioides, and Campostoma anomalum from six streams of varying water quality. Allozyme electrophoresis revealed that the most ecologically specialized species, E. caeruleum, was the least variable (P = 68.4%, Hobs = 1.2%). Etheostoma blennioides was intermediate in specialization and variation (P = 77.8%, Hobs = 7.8%), and the least specialized species, C. anomalum, had the most variation (P = 90.0%, Hobs = 12.1%). This patt

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Sheela, Soumya, Waad Kheder, and A. B. Rani Samsudin. "Investigating the influence of titanium particle size and concentration on osteogenic response of human osteoblasts – in vitro study." Biomaterial Investigations in Dentistry 11 (June 13, 2024): 66–75. http://dx.doi.org/10.2340/biid.v11.40843.

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Purpose: The purpose of this study was to investigate the correlation between the size and concentration of titanium particles and the osteogenic response of human osteoblasts (HOB). Materials and Methods: Different concentrations of titanium dioxide nano- and micro-particles were prepared and their biocompatibility on HOBs was analyzed using XTT assay. The changes in the actin cytoskeletal organization were studied by confocal laser scanning microscopy. The generation of intracellular reactive oxygen species (ROS) by HOBs after exposure to titanium dioxide particles was analyzed using ROS ass

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Matsuoka, Hironori, Akira Katsuki, Yoshihiro Furumiya, and Fukusaburo Yamamoto. "Fundamental Research on Hard Materials for Hobs." Transactions of the Japan Society of Mechanical Engineers Series C 59, no. 559 (1993): 903–8. http://dx.doi.org/10.1299/kikaic.59.903.

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27

NEWBOROUGH, M., and S. D. PROBERT. "ENERGY-CONSCIOUS DESIGN IMPROVEMENTS FOR ELECTRIC HOBS." Foodservice Research International 4, no. 4 (1987): 233–57. http://dx.doi.org/10.1111/j.1745-4506.1987.tb00113.x.

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28

Simon, V. "Computer aided manufacturing of high precision hobs." International Journal of Machine Tools and Manufacture 28, no. 4 (1988): 443–52. http://dx.doi.org/10.1016/0890-6955(88)90057-0.

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Veziroglu, Salih, Mustafa Ayna, Theresa Kohlhaas, et al. "Marine Algae Incorporated Polylactide Acid Patch: Novel Candidate for Targeting Osteosarcoma Cells without Impairing the Osteoblastic Proliferation." Polymers 13, no. 6 (2021): 847. http://dx.doi.org/10.3390/polym13060847.

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Biodegradable collagen-based materials have been preferred as scaffolds and grafts for diverse clinical applications in density and orthopedy. Besides the advantages of using such bio-originated materials, the use of collagen matrices increases the risk of infection transmission through the cells or the tissues of the graft/scaffold. In addition, such collagen-based solutions are not counted as economically feasible approaches due to their high production cost. In recent years, incorporation of marine algae in synthetic polymers has been considered as an alternative method for preparation graf

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Obata, Akiko, and Toshihiro Kasuga. "Cellular Activity on Siloxane-Doped Poly(Lactic Acid)/Vaterite Composite Scaffolds." Key Engineering Materials 361-363 (November 2007): 399–402. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.399.

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Cellular activities of human mesenchymal stem cells (MSCs) and osteoblasts (HOBs) on a silicon-releasable scaffold, which is siloxane-doped poly(lactic acid) / vaterite composite coated with hydroxycarbonate apatite (SPV-H), were estimated using two types of media, with or without organic factors, dexamethasone (Dex) and β-glycerophosphate (β-GP). The culture tests using MSCs shows that the level of alkaline phosphatase (ALP) activity in the cells cultured on SPV-H increased for 21-day culturing in medium without Dex and β-GP. The proliferation of MSCs on SPV-H was significantly higher than th

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Schmidt, Yvonne, Filip Simunovic, Sandra Strassburg, Dietmar Pfeifer, G. Björn Stark та Günter Finkenzeller. "miR-126 regulates platelet-derived growth factor receptor-α expression and migration of primary human osteoblasts". Biological Chemistry 396, № 1 (2015): 61–70. http://dx.doi.org/10.1515/hsz-2014-0168.

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Abstract Adequate vascularization is an essential requirement for bone development, fracture healing and bone tissue engineering. We have previously described the coculture of primary human osteoblasts (hOBs) and human endothelial cells (HUVECs), designed to investigate the interactions between these cells. In this system, we showed that cocultivation of these two cell types leads to a downregulation of platelet-derived growth factor receptor-α (PDGFR-α) in hOBs, which was a consequence of reduced mRNA stability. In the current study we investigated the possible involvement of microRNAs in thi

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Hodgyai, Norbert, Mircea Viorel Drăgoi, Ferenc Tolvaly-Roşca, and Márton Máté. "About the Grinding of Gear Hob’s Rake Face." Műszaki Tudományos Közlemények 16, no. 1 (2022): 31–35. http://dx.doi.org/10.33894/mtk-2022.16.06.

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Abstract The most simple and robust construction of the monolithic gear hobs present a common helical rake face for a given line of teeth, whose generatrix is a straight-line segment perpendicular to the hob’s axis while its directory is a helix, perpendicular to the pitch helix. As a consequence, constructive rake angles are zero on all edges. Total curvatures of such a surface are negative. Thus, it can be grinded only using the conical surface of a platter type grinding wheel, or a grinding bit. Despite this, some industry practices, possibly for reasons of simplicity and cost lowering, inv

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Yang, Shuying, Weifang Chen, Zhiqiang Wang, and Yanfeng Zhou. "Modelling and experiment of gear hob tooth profile error for relief grinding." Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture 235, no. 13 (2021): 2081–92. http://dx.doi.org/10.1177/09544054211017297.

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Gear hob is an important tool that is most used in gear processing. Hob accuracy directly exerts an overwhelming influence on the quality of the processed gear. Generally, the hob tooth profile accuracy is mainly determined by relief grinding process. Studies on tooth profile errors of gear hobs caused by severe friction and cutting with the high-speed rotation of the wheel during the form grinding machining of hobs are limited. Thus, a theoretical model of the tooth profile error prediction under different machining parameters was established based on the analysis of coupling influence of hig

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Harun, Noor Hanisa, Gabriele Ruth Anisah Froemming, Aletza Mohd Ismail, Hapizah Nawawi, Siti Shuhada Mokhtar, and Suhaila Abd Muid. "Osteoblast Demineralization Induced by Oxidized High-Density Lipoprotein via the Inflammatory Pathway Is Suppressed by Adiponectin." International Journal of Molecular Sciences 23, no. 23 (2022): 14616. http://dx.doi.org/10.3390/ijms232314616.

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Low mineralization activity by human osteoblast cells (HOBs) indicates abnormal bone remodeling that potentially leads to osteoporosis. Oxidation, the most prominent form of high-density lipoprotein (HDL) modification, is suggested to affect bone mineralization through the inflammatory pathway. Adiponectin, which possesses anti-inflammatory activity, is postulated to have the ability to suppress the detrimental effects of oxidized HDL (oxHDL). This study aimed to investigate the effects of HDL before and after oxidation on markers of mineralization and inflammation. The protective effects of a

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Karpuschewski, B., M. Beutner, M. Wengler, and M. Köchig. "HIGH SPEED GEAR HOBBING WITH CEMENTED CARBIDE HOBS." MM Science Journal 2014, no. 04 (2014): 527–32. http://dx.doi.org/10.17973/mmsj.2014_12_201419.

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36

Sandler, A. I. "Technique of Tooth Relieving for Gear Cutting Hobs." Bulletin of Kalashnikov ISTU 23, no. 4 (2020): 29. http://dx.doi.org/10.22213/2413-1172-2020-4-29-38.

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Затылованная поверхность боковой стороны зубьев червячной фрезы - это аналог винтовой поверхности с углом подъема, увеличенным для одной и уменьшенным для другой стороны зуба относительно угла подъема производящей поверхности. Основные недостатки действующей технологии затылования: искажение профиля производящей поверхности в ходе переточек фрез для восстановления режущих свойств инструмента, зависимость наладки процесса затылования от диаметра шлифовального круга и высокая трудоемкость достижения требуемой точности профиля производящей рейки фрезы.Предложено изготавливать боковые поверхности

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Huang, Chin-Lung, Guan-Shing Lee, and Li-Sheng Chang. "A new solution for sharpening helical flute hobs." Mechanism and Machine Theory 164 (October 2021): 104419. http://dx.doi.org/10.1016/j.mechmachtheory.2021.104419.

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HAMADA, Koutaro, Hidehiro YOSHINO, and Fumihiro OHSHIMA. "H32 Relieving of Helical Pinion Cutters with Hobs." Proceedings of Conference of Kyushu Branch 2011.64 (2011): 301–2. http://dx.doi.org/10.1299/jsmekyushu.2011.64.301.

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39

Piotrowski, Andrzej. "The impact of sharpening on accuracy of hobs." Mechanik, no. 7 (July 2015): 565/681–565/694. http://dx.doi.org/10.17814/mechanik.2015.7.285.

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AINOURA, Masato, and Kisaburo NAGANO. "Wear on TiN-coated high speed steel hobs." Transactions of the Japan Society of Mechanical Engineers Series C 52, no. 477 (1986): 1606–11. http://dx.doi.org/10.1299/kikaic.52.1606.

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Máté, Márton, and Dénes Hollanda. "About the Profile Accuracy of the Involute Gear Hob." Acta Universitatis Sapientiae Electrical and Mechanical Engineering 9, no. 1 (2017): 5–18. http://dx.doi.org/10.1515/auseme-2017-0006.

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Abstract Gear hobs are the most widely and frequently used gear cutting tools. During the time passed between the moment of invention (Schiele, 1876) and the present, gear hobs reached a considerable evolution regarding the geometry, the profile of the edge, the relieving technologies finalizing in the latest constructive and design solutions. This paper deals with the calculus of the edge profile in the case the basic worm of the hob has involute helicoid surfaces. In order to obtain a constant grinding allowance on the relief faces of the gear hob teeth it is necessary to compute the edge of

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Terruzzi, Ileana, Anna Montesano, Pamela Senesi, et al. "L-Carnitine Reduces Oxidative Stress and Promotes Cells Differentiation and Bone Matrix Proteins Expression in Human Osteoblast-Like Cells." BioMed Research International 2019 (January 20, 2019): 1–13. http://dx.doi.org/10.1155/2019/5678548.

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Bone fragility and associated fracture risk are major problems in aging. Oxidative stress and mitochondrial dysfunction play a key role in the development of bone fragility. Mitochondrial dysfunction is closely associated with excessive production of reactive oxygen species (ROS). L-Carnitine (L-C), a fundamental cofactor in lipid metabolism, has an important antioxidant property. Several studies have shown how L-C enhances osteoblastic proliferation and activity. In the current study, we investigated the potential effects of L-C on mitochondrial activity, ROS production, and gene expression i

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Kasuga, Toshihiro, Akiko Obata, Hirotaka Maeda, and Larry L. Hench. "Preparation of Poly(Lactic Acid) Composites Containing Vaterite for Bone Repair." Materials Science Forum 539-543 (March 2007): 617–22. http://dx.doi.org/10.4028/www.scientific.net/msf.539-543.617.

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Calcium carbonate (vaterite)-containing poly(lactic acid) (PLA) composites (CCPCs) were prepared for novel biomaterials that are expected to exhibit high bioresorbability and osteoconductivity. CCPC containing 30% vaterite showed bending strengths of 40~50 MPa. 13C CP/MAS-NMR spectrum of CCPC suggested the formation of a bond between Ca2+ ion and COOgroup. The bond may play an important role in the improvement of the mechanical properties. On the surface of CCPC containing 30 % vaterite, ~10-μm-thick hydroxycarbonate apatite (HCA) formed after 1 day of soaking in SBF at 37oC. After 1-week incu

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Hodgyai, Norbert, Márton Máté, Gheorghe Oancea, and Mircea-Viorel Dragoi. "Gear Hobs—Cutting Tools and Manufacturing Technologies for Spur Gears: The State of the Art." Materials 17, no. 13 (2024): 3219. http://dx.doi.org/10.3390/ma17133219.

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The present work aims to provide the readers with a bird’s-eye view of the general domain of cylindrical gear manufacturing technologies, including the cutting tools used, and related topics. The main scientific sources are explored to collect data about the subject. A systematization of the scientific works is completed, to emphasize the main issues the researchers have focused on in the past years in the domain. Several specific aspects are investigated: chip-forming process, cutting tool lifetime, the materials used to produce gear hobs, temperature and lubrication, the cutting tool geometr

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Kaiser, Martin F., Ulrike Heider, Maren Mieth, et al. "Induction of CXCL1 in Osteoblasts by Myeloma Cells Promotes Migration of Osteoclast Precursors." Blood 120, no. 21 (2012): 441. http://dx.doi.org/10.1182/blood.v120.21.441.441.

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Abstract Abstract 441 Introduction Multiple myeloma (MM) causes a dysbalance in the bone microenvironment between bone building osteoblasts and bone resorbing osteoclasts (OCs), with an increase in OC recruitment, differentiation and activation, leading to myeloma bone disease (MBD). Presence of MBD has a major impact on the quality of life of MM patients and novel treatment approaches for MBD are urgently needed. Several factors have been identified that play a role in this process, e.g. receptor activator of NF-kB ligand (RANKL). However, the pathomechanism of increased osteoclast recruitmen

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NISHIDA, Noriteru, Makoto KAWANO, and Hiroshi TODA. "A calculating method of cutting edge profile of hobs." Journal of the Japan Society for Precision Engineering 52, no. 6 (1986): 1061–67. http://dx.doi.org/10.2493/jjspe.52.1061.

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Petukhov, Yu E., P. V. Domnin, and S. A. Zheltikov. "Manufacture of Hard-Alloy Hobs by Electrical Discharge Machining." Russian Engineering Research 41, no. 10 (2021): 936–38. http://dx.doi.org/10.3103/s1068798x21100221.

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Has, U., and D. Wassilew. "Temperature control for food in pots on cooking hobs." IEEE Transactions on Industrial Electronics 46, no. 5 (1999): 1030–34. http://dx.doi.org/10.1109/41.793352.

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AINOURA, Masato, Kisaburo NAGANO, and Hiroshi TUKAMOTO. "Hob shifting for TiN-coated high speed steel hobs." Transactions of the Japan Society of Mechanical Engineers Series C 54, no. 501 (1988): 1131–34. http://dx.doi.org/10.1299/kikaic.54.1131.

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Adams, F. J., and O. T. Evans. "Cooking by light-a revolutionary approach to electric hobs." IEEE Transactions on Industry Applications 24, no. 1 (1988): 33–38. http://dx.doi.org/10.1109/28.87246.

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