Relevant bibliographies by topics / Hoechst UK

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Academic literature on the topic 'Hoechst UK'

Author: Grafiati
Published: 4 June 2021
Last updated: 16 February 2022

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Journal articles on the topic "Hoechst UK"

1

Rodríguez-Farré, Eduardo, Marcel Roberfroid, and Giovanni N. Fracchia. "Research and Development of In Vitro Pharmacotoxicology: A European Perspective." Alternatives to Laboratory Animals 21, no. 2 (April 1993): 285–93. http://dx.doi.org/10.1177/026119299302100224.

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The experts taking part in the Workshop were: E. Rodríguez-Farré ( Coordinator); G.N. Fracchia, (Secretary); M. Adolphe, École des Hautes Études, Paris, France); P.H. Bach (University of East London, UK); M. Baeder (Hoechst Ltd, Hattersheira, Germany); R. Bass (BGA, Berlin, Germany); H.G. Baumgarten (Frei Universität, Berlin, Germany); H. Bazin (DGXII, CEC, Brussels, Belgium); P. Bentley (Ciba-Geigy, Basle, Switzerland); A. Boobis (Royal Postgraduate Medical School, London, UK); J. Castell (Hospital La Fé, Valencia, Spain); J.P. Contzen (DGXII, CEC, Brussels, Belgium); A. Cordier (Sandoz Pharma Ltd, Basle, Switzerland); J. Diezi (Université de Lausanne, Switzerland); L. Dubertret (INSERM U-312, Creteil, France); P.M. Fasella (DGXII, CEC, Brussels, Belgium); J.H. Fentem (FRAME, Nottingham, UK); A. Guillouzo (INSERM U-49, Rennes, France); I. Kimber (Zeneca, Macclesfield, UK); T. Krieg (Universität zu Koln, Germany); A. Mantovani (Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy); K. Miller (BIBRA, Carshalton, UK); J.P. Morin (INSERM U-295, Rouen, France); D. Paul (Fraunhofer Institut für Toxikologie und Aerosolforschung, Hannover, Germany); P.W.J. Peters (Riijkinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, The Netherlands); J. Picard (Faculté des Sciences, Louvain la Neuve, Belgium); D. Poggiolini (Ministry of Health, Rome, Italy); C.M. Regan (University College, Dublin, Ireland); C.A. Reinhardt (SIAT, Zurich, Switzerland); B. Robaire (McGill University, Montreal, Canada); M. Roberfroid (Université Catholique de Louvain, Brussels, Belgium); V. Rogiers (Vrije Universiteit Brussels, Belgium); J. Rueff (Istituto de Higiene e Medicina Tropical, Lisbon, Portugal); H. Spielmann (ZEBET, Berlin, Germany); H. Stolte (Medizinische Hochschule, Hannover, Germany); J. van Noordwijk (European Pharmacopeia Commission, Bosch en Duin, The Netherlands); E. Walum (University of Stockholm, Sweden); D.C. Williams (Trinity College, Dublin, Ireland); and M. Yaniv (Institut Pasteur, Paris, France), and their contributions are gratefully acknowledged.
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Peters, A. R., L. A. Dwyer, A. Dawson, P. A. Canham, and J. D. Mackinnon. "Effects of Buserelin on day of service or 12 days post service on farrowing rate and litter size to first service in outdoor sows and gilts." Proceedings of the British Society of Animal Science 1999 (1999): 176. http://dx.doi.org/10.1017/s1752756200003318.

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The problem of seasonal infertility in pigs has been recognised for many years. The infertility complex can may be manifested by increased returns to service, prolonged weaning to oestrus intervals and decreased litter size. The purpose of this trial was to evaluate the effects of Buserelin treatment on fertility in sows and gilts during the seasonally infertile period.A total of 1231 mixed parity sows and gilts from five outdoor herds in East Anglia were randomly assigned to one of three treatment groups. Any sows not presented for service at first post weaning oestrus were excluded. All sows and gilts judged to be in adequate health and condition to be kept in a commercial breeding herd were included. Group C sows and gilts were given no treatment. Group R1 sows and gilts were injected i.m. with 8μg Buserelin (2.0ml Receptal; Hoechst Roussel Vet UK Ltd) on the day of service.
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McMillen, S. R., S. M. Rhind, and A. S. McNeilly. "Effect of body condition on ovarian sensitivity to exogenous FSH in ewes in which endogenous gonadotrophin secretion is suppressed." Proceedings of the British Society of Animal Production (1972) 1991 (March 1991): 172. http://dx.doi.org/10.1017/s0308229600021218.

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The results of previous experiments indicate that the effect of body condition (BC) on ovulation rate is mediated through changes in the number of large, potentially ovulatory, ovarian follicles. However, these differences in follicle populations were not associated with consistent differences in gonadotrophin profiles. It was therefore postulated that effects of level of BC on follicle development and ovulation rate are due to differential ovarian sensitivity of FSH.Two groups of 20 Scottish Blackface ewes were fed differentially so that they achieved mean (±s.e.m.) body condition scores of 1.78±0.017 (Low; L) and 2.94±0.031 (High; H) by 2 weeks before sample collection. They were then fed to maintain these body conditions throughout the remainder of the experiment. Four weeks before study, Alzet minipumps (Charles Rivers UK Ltd.) containing GnRH agonist (buserilin; Hoechst AG; Frankfurt, F.R.G.) were inserted, subcutaneously, in all ewes. This treatment partially suppresses FSH secretion and totally inhibits LH pulses so that growth of ovarian follicles >2.5 mm in diameter is inhibited.
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Silva, Danielle Fabiola Pereira, Dalmo Lopes Siqueira, Rosana Gonçalves Pires Matias, Sílvia Paula Oliveira, Leila Cristina Rosa de Lins, and Luiz Carlos Chamhum Salomão. "Desempenho de filmes comestíveis em comparação ao filme de policloreto de vinila na qualidade pós-colheita de mexericas 'Poncã'." Ciência Rural 42, no. 10 (August 28, 2012): 1770–73. http://dx.doi.org/10.1590/s0103-84782012005000076.

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O objetivo do trabalho foi avaliar o efeito de diferentes concentrações de fécula de mandioca na vida útil pós-colheita de frutos 'Mexerica Poncã' durante o armazenamento em temperatura ambiente em substituição ao filme de policloreto de vinila (PVC). Os frutos foram imersos em suspensões aquosas de fécula de mandioca a 0; 1; 2 e 3% (m:v) acrescidas de 0,5mL L-1 de óleo mineral Assist (Bayer Cropscience, da empresa Hoechst Schering AgrEvo UK Ltd. - Inglaterra) ou recobertos com PVC de 14µm de espessura, e armazenados a temperatura ambiente. As amostragens foram realizadas no tempo zero (início do experimento) e a cada dois dias, por oito dias. Foram avaliadas a perda de massa fresca, rendimento de suco, sólidos solúveis (SS), acidez titulável (AT), relação SS/AT e teor de ácido ascórbico. A perda de massa fresca aumentou durante o armazenamento, sendo mais acentuada na dose de 2%. A redução no teor de ácido ascórbico foi maior nos frutos recobertos com filme de PVC. A concentração de fécula de mandioca a 1% foi a que proporcionou melhores resultados quanto à manutenção da qualidade físico-química de frutos de 'Mexerica Poncã' durante oito dias de armazenamento.
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Kirby, P. S., N. A. Watson, D. G. Rennie, and T. O. Jones. "Timing of fish meal supplementation for finishing beef cattle offered grass silage." Proceedings of the British Society of Animal Production (1972) 1986 (March 1986): 113. http://dx.doi.org/10.1017/s0308229600016196.

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Results from three previous experiments with finishing cattle on an 18-month beef system indicate that the major increases in daily live-weight gain (DLG) occur within the first 50 to 60 days of supplementation with fish meal. Hence, it may be possible to remove fish meal from the diet after the initial two months of the finishing winter without any subsequent effect on animal performance.For the last nine weeks at grass the experimental cattle were given 1.4-kg/head/day dried sugar beet pulp nuts. On housing this allowance was increased to 3.0 kg and the 48 British Friesian steers were offered grass silage ad libitum (round bale silage for one week and precision-chopped clamp silage thereafter). The 3.0-kg dried sugar beet pulp was given for five days and after a 10-day changeover period the nuts were replaced by 15-kg potatoes. Cattle were offered the basal diet of precision-chopped silage and potatoes for 12 days before starting the experiment.Steers were implanted with 300-mg trenbolone acetate (Finaplix, Hoechst UK Ltd, Milton Keynes) and 36-mg zeranol (Ralgro, Crown Chemical Company Ltd, Lamberhurst) 20 days before randomisation.
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Norton, Lord Kings. "Extract from A Wrack Behind: Myself, when old." Aeronautical Journal 103, no. 1022 (April 1999): 221. http://dx.doi.org/10.1017/s0001924000096573.

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I am not quite sure when I became old, but I think I must date it in my seventies when I retired from a variety of activities and settled into a more sedentary style of life. I retired from Dowty Rotol and Bergers (and so Hoechst UK) in 1975, from the Royal Institution in 1976, from Ricardo’s and British Printing Corporation in 1977 and sold Withers Estates, very profitably for the Withers family, in 1981. I was left with the chairmanships of two tiny companies, Land-speed and Cotswold Research. While Landspeed has not served its purpose, Cotswold Research has its place in history. Both companies are concerned with the inventions of Professor Eric Laithwaite, who demonstrated in model and prototype form tracked hovercraft powered by the linear motor. Landspeed failed to develop this, through lack of funds, to a commercially viable transport system, though the Japanese appear to have done so. Cotswold Research, however, made a success of an adaptation of the linear motors to the separation of aluminium from scrap material and for their work, which ended in profitable industrial apparatus and a big saving in manpower, Mr A.P. Bird and I received the Prince of Wales Award in 1986.
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Drew, S. B., and A. R. Peters. "The effect of treatment with a gonadotrophin releasing hormone on the fertility of dairy cows." Proceedings of the British Society of Animal Production (1972) 1991 (March 1991): 171. http://dx.doi.org/10.1017/s0308229600021206.

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Work in New Zealand has suggested that treatment of dairy cows with buserelin an analogue of GnRH between days 11 and 13 after insemination can increase pregnancy rate by reducing embryo loss (MacMillan, Taufa and Day, 1986). This effect is probably mediated via a luteoprotective mechanism (MacMillan, Thatcher & Drost 1989; Thatcher, MacMillan, Hansen & Drost, 1989). The present study was carried out to attempt to confirm this effect of buserelin under UK conditions.A total of 660 Holstein/Friesian cows on 10 commercial dairy farms were used. The cows were paired according to date, of previous calving and allocated at random to control or treated group on the day of service. Only cows in the parity range 1-5 with no obvious reproductive disorders were used. Bulls and inseminators were used on the same number of cows in each group. Milk samples were taken on the day of service for progesterone assay. Cows not in oestrus were removed from the study. Cows in treated groups were given an intramuscular injection of 10 ug buserelin [2.5 ml Receptal, Hoechst] 12 days after first insemination. Cows not observed to return to oestrus before Day 24 were re-sampled for progesterone assay. Pregnancy was confirned by palpation or ultrasonic scanning at six weeks.
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Eshel, Alex, Najim A. Abdulwahid, N. Adjeidu Armar, Judith M. Adams, and Howard S. Jacobs. "Pulsatile luteinizing hormone–releasing hormone therapy in women with polycystic ovary syndrome**Supported in part by grant from Birthright to Dr. N. A. Armar and by Hoechst UK." Fertility and Sterility 49, no. 6 (June 1988): 956–60. http://dx.doi.org/10.1016/s0015-0282(16)59943-9.

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Romano, Vito, Mohit Parekh, Alessandro Ruzza, Colin E. Willoughby, Stefano Ferrari, Diego Ponzin, Stephen B. Kaye, and Hannah J. Levis. "Comparison of preservation and transportation protocols for preloaded Descemet membrane endothelial keratoplasty." British Journal of Ophthalmology 102, no. 4 (November 13, 2017): 549–55. http://dx.doi.org/10.1136/bjophthalmol-2017-310906.

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Background/aimsDescemet membrane endothelial keratoplasty (DMEK) preparation is technically demanding and is a limiting factor for uptake of this kind of surgery. Supply methods that simplify the procedure for surgeons are key to increasing uptake. This study compares two different shipping protocols for DMEK.MethodsAn 8.5 mm DMEK graft was punched, marked and loaded for transportation in two different conditions: (A) endothelium trifolded inwards in organ culture conditions (n=7) and (B) endothelium rolled outwards in hypothermic conditions (n=7). Tissues were shipped from Italy to the UK, then analysed for orientation, endothelial cell density, denuded areas, cell mortality, triple viability staining (Hoechst/ethidium homodimer/calcein AM (HEC)), immunolocalisation of ZO-1 and Na/K-ATPase proteins, visualisation of actin filaments using phalloidin and histological analysis using H&E on paraffin-embedded sections.ResultsAll tissues clearly showed the mark used for graft orientation. After shipping in condition A, there was an increase in cell mortality of 8.1% and in denuded areas of 22.4%, whereas for condition B there was an increase in cell mortality of 14.2% and in denuded areas of 34.3% after shipping. HEC staining revealed areas of viable cells and apoptotic cells, with large denuded areas found in the periphery for condition B and within folds for condition A.ConclusionsPrestripped preloaded DMEK grafts retained sufficient viable cells for transplantation, with condition A (endothelium-in) offering the advantage of greater flexibility of use due to a longer shelf-life. HEC analysis provides further detailed information as to the status of DMEK grafts and should be used in future similar studies.
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Bentick, Bernard, Robert W. Shaw, Claire A. Iffland, Graham Burford, and Albert Bernard. "A randomized comparative study of purified follicle stimulating hormone and human menopausal gonadotropin after pituitary desensitization with Buserelin**Buserelin, Hoechst UK Ltd., Pharmaceutical Division, Hounslow, Middlesex, United Kingdom. for superovulation and in vitro fertilization." Fertility and Sterility 50, no. 1 (July 1988): 79–84. http://dx.doi.org/10.1016/s0015-0282(16)60012-2.

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Book chapters on the topic "Hoechst UK"

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"In Pharmon v Hoechst [1985] ECR 2281; [1985] 3 CMLR 775 a licence of right to make the products in question in the UK was granted, but with a ban on exports written into it. Pharmon nevertheless exported the product to the Netherlands and Hoechst sought an injunction to stop the sale of the drug in that country. The European Court of Justice held that Hoechst had not consented to the manufacture of the product by the compulsory licensee. The exclusive right of first marketing must be protected, therefore the patentee could prevent the marketing of parallel imports in such circumstances. The Advocate General added a proviso which was not adopted by the court that this would be different if the patent holder had expressly or impliedly consented to the grant of a compulsory licence. This might, for example, be the case where there were links between the patent holder and the compulsory licensee such as where they were parent and subsidiary." In Sourcebook on Intellectual Property Law, 118–23. Routledge-Cavendish, 1997. http://dx.doi.org/10.4324/9781843142928-25.

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