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1

Sarmiento-Ortiz, Fabian, Blanca Topón-Visarrea, Christian Iza, Joel Morales, and Vecquer León. "Design of a load elevator as a measure to reduce ergonomic risks." IOP Conference Series: Earth and Environmental Science 1370, no. 1 (2024): 012011. http://dx.doi.org/10.1088/1755-1315/1370/1/012011.

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Abstract Manual handling of loads in work environments poses significant ergonomic risks, leading to musculoskeletal disorders and injuries. To address this, mechanical solutions are essential to optimize processes and ensure employees’ health and well-being. In this study utilized four methodologies: the Ergonomic Checklist, NIOSH Equation, Snook and Cirello Tables, and the INSHT Technical Guide. These tools evaluated the physical load and risks of manual lifting. Concurrently, a load lifter was developed, utilizing a tractor system powered by an electric motor and a chain hoist, all automate
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Patel, Shruti B., Jon Jurica, and Xiaoqing Hua. "Implementation of a high throughput automated platform for residual DNA quantitation." PLOS One 20, no. 4 (2025): e0322133. https://doi.org/10.1371/journal.pone.0322133.

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Host cell DNA is an impurity from cell-based manufacturing processes that must be controlled and monitored to ensure drug purity and safety. Conventional methods for measurement of residual host cell DNA in therapeutic protein require numerous preparations of plates, DNA extraction from the protein samples, followed by quantification of the extracted DNA using real-time PCR (qPCR). Preparation of plates for extraction is the most laborious step, including numerous manual steps such as sample dilution, standard curve preparation, as well as reagent and sample plate preparation. Additionally, mu
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Naresh, Chappidi, PVVSSR Krishna, G. V. V. Satyanaryana, and Laith H. Alzubaidi. "Holistic Approach to Multipurpose Stadium Design: Advance Structural Analysis Strategies." E3S Web of Conferences 529 (2024): 04004. http://dx.doi.org/10.1051/e3sconf/202452904004.

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The current paper discusses about the work made on the study to develop a highly adaptable and versatile stadium, departing from traditional single-purpose designs, with a focus on maximizing utility. With a substantial gross seating capacity of 61424, the stadium is intended to host various sports competitions and large public gatherings. The planning process relies on Computer-Aided Design (CAD) and Building Information Modelling (BIM) software to ensure precise detailing in structural aspects. Advanced engineering software enhances structural analysis, allowing for comprehensive investigati
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Bento, Clara M., Maria Salomé Gomes, and Tânia Silva. "Evolution of Antibacterial Drug Screening Methods: Current Prospects for Mycobacteria." Microorganisms 9, no. 12 (2021): 2562. http://dx.doi.org/10.3390/microorganisms9122562.

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The increasing resistance of infectious agents to available drugs urges the continuous and rapid development of new and more efficient treatment options. This process, in turn, requires accurate and high-throughput techniques for antimicrobials’ testing. Conventional methods of drug susceptibility testing (DST) are reliable and standardized by competent entities and have been thoroughly applied to a wide range of microorganisms. However, they require much manual work and time, especially in the case of slow-growing organisms, such as mycobacteria. Aiming at a better prediction of the clinical
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McNeil, Andrew, Kelsey Parks, Michael Pogharian, et al. "26 Evaluating AI models trained with varying amounts of expert feedback for chronic graft-versus-host disease skin assessment in photos of patients with diverse skin tones." Journal of Clinical and Translational Science 9, s1 (2025): 9–10. https://doi.org/10.1017/cts.2024.717.

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Objectives/Goals: Manual skin assessment in chronic graft-versus-host disease (cGVHD) can be time consuming and inconsistent (>20% affected area) even for experts. Building on previous work we explore methods to use unmarked photos to train artificial intelligence (AI) models, aiming to improve performance by expanding and diversifying the training data without additional burden on experts. Methods/Study Population: Common to many medical imaging projects, we have a small number of expert-marked patient photos (N = 36, n = 360), and many unmarked photos (N = 337, n = 25,842). Dark skin (Fit
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Ayunda, Mutiara, Evino Sugriarta, Aidil Onasis, Sri Lestari Adriyanti, and Awaluddin Awaluddin. "Analisis Potensi Bahaya pada Pekerjaan dengan Metode Job Safety Analysis (JSA) di PT Sari Teknindo Perkasa Tahun 2024." Jurnal Kesehatan Lingkungan Mandiri 3, no. 1 (2024): 1–16. https://doi.org/10.33761/jklm.v3i1.1622.

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Potential hazards in industrial activities can cause work accidents. These hazards originate from humans, machines, materials and methods at work caused by the application of an occupational health and safety management system that is still not effective. Therefore, it is necessary to implement an OHS management system in recognizing potential hazards to prevent work accidents. The Job Safety Analysis (JSA) method can be applied in analyzing potential hazards at work then determining effective control measures to prevent risks that can occur. The purpose of this study is to determine the poten
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Kubiciel-Lodzińska, Sabina, Jolanta Maj, Katarzyna Widera, Piotr Bębenek, Bogdan Ruszczak, and Marta Sokołowska. "Escaping brain waste. Work experience and qualifications of highly skilled Ukrainians in Poland." Scientific Papers of Silesian University of Technology. Organization and Management Series 2023, no. 170 (2023): 267–82. http://dx.doi.org/10.29119/1641-3466.2023.170.16.

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Purpose: The research aimed to identify what causes some highly skilled migrants from Ukraine to work according to their qualifications and others work below their qualifications. Design/methodology/approach: This article discusses the results of a survey conducted among 248 highly skilled economic migrants from Ukraine working in Poland. Two groups were analysed: working according to their qualifications and working below their qualifications. The study was carried out between December 2021 and March 2022. The CATI method has been used. Findings: There is a statistically significant relations
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Sailon, Zamheri Ahmad, Wilza Romi, and Zainuddin. "RANCANG BANGUNG MESIN BOR TANAH UNTUK MEMBUAT LUBANG RESAPAN AIR (BIOPORI)." AUSTENIT 9, no. 2 (2017): 27–36. https://doi.org/10.5281/zenodo.4547631.

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<em>The designed biopore drill machine uses manual manual hoist / manual crank system that serves to raise and lower the drill bit. Engines that are connected to the drill bit vertically in addition to functioning to rotate the drill bit also serve as a weight so that the drill bit can enter the ground. In addition, the biopori drill machine is made of a rectangle with the aim that the machine at the time of operation becomes steady (not shifted) and the legs are wheeled in order tobe easy to move.around. Biopori drill machine is a modification of existing tools, both variations of the form an
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Tantri Rahayu, Fatimah Azzahri, Khoirunnisa Khoirunnisa, and Suhariyanti Suhariyanti. "Pengelolaan dan Pelayanan Perpustakaan Dengan Sistem SLIMS 9 Berbasis Local Host." Jurnal Insan Pengabdian Indonesia 2, no. 1 (2024): 40–51. https://doi.org/10.62007/jouipi.v2i1.254.

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The development of information technology in the current technological era is growing very rapidly. The development of information technology has had a major influence on the development of libraries, especially in terms of managing information. Indeed, it is not something bad or even prohibited if you continue to manage the library using manual methods, there are several things that need to be considered, why libraries in the current context need an automation system. All libraries are required to be able to keep up with advances in information technology in the current are of digitalization.
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Garg, Dr Rishabh. "Facial Recognition Student Attendance System Web Application." International Journal for Research in Applied Science and Engineering Technology 12, no. 4 (2024): 5138–40. http://dx.doi.org/10.22214/ijraset.2024.61099.

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Abstract: In the digital era, facial recognition technologies are indispensable in almost every business. Face is one biometric that is commonly used. Acknowledgement. In addition to being helpful for identification, security, and authentication, it offers a host of other advantages. Despite their increased accuracy, fingerprint and iris recognition technologies are still widely used because of their non-invasive and contactless nature. Facial recognition systems may also be used to show attendance in offices, classrooms, universities, and other contexts. This system's objective is to develop
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Cook, M. E., A. Leigh, and D. M. Watson. "Hiding in plain sight: experimental evidence for birds as selective agents for host mimicry in mistletoes." Botany 98, no. 9 (2020): 525–31. http://dx.doi.org/10.1139/cjb-2019-0209.

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Many Australian mistletoe species are cryptic, closely resembling their host foliage and overall appearance. Seed-dispersing birds have been proposed as a selective agent for host resemblance, with cryptic mistletoes only located by thoroughly searching through canopies regardless of infection status, boosting mistletoe populations by increasing the frequency of seeds dispersed to uninfected hosts; however, this idea is as yet untested. We measured bird visitation to fruiting mistletoes (n = 20) over two consecutive days, with manual defoliation of the mistletoe occurring before observation be
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McClanahan, Patrick D., Luca Golinelli, Tuan Anh Le, and Liesbet Temmerman. "Automated scoring of nematode nictation on a textured background." PLOS ONE 18, no. 8 (2023): e0289326. http://dx.doi.org/10.1371/journal.pone.0289326.

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Entomopathogenic nematodes, including Steinernema spp., play an increasingly important role as biological alternatives to chemical pesticides. The infective juveniles of these worms use nictation–a behavior in which animals stand on their tails–as a host-seeking strategy. The developmentally-equivalent dauer larvae of the free-living nematode Caenorhabditis elegans also nictate, but as a means of phoresy or "hitching a ride" to a new food source. Advanced genetic and experimental tools have been developed for C. elegans, but time-consuming manual scoring of nictation slows efforts to understan
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Fallon, Ann M., and Elissa M. Carroll. "Virus-like Particles from Wolbachia-Infected Cells May Include a Gene Transfer Agent." Insects 14, no. 6 (2023): 516. http://dx.doi.org/10.3390/insects14060516.

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Wolbachia are obligate intracellular bacteria that occur in insects and filarial worms. Strains that infect insects have genomes that encode mobile genetic elements, including diverse lambda-like prophages called Phage WO. Phage WO packages an approximately 65 kb viral genome that includes a unique eukaryotic association module, or EAM, that encodes unusually large proteins thought to mediate interactions between the bacterium, its virus, and the eukaryotic host cell. The Wolbachia supergroup B strain, wStri from the planthopper Laodelphax striatellus, produces phage-like particles that can be
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14

Genia Auberta and Agus Edy Pramono. "Risk Analysis Of Musculoskeletal Disorders (MSDs) Of The Material Handling Process In Waste Processing Operators Using The Rapid Whole Body Assessment Method." Recent in Engineering Science and Technology 2, no. 04 (2024): 44–53. http://dx.doi.org/10.59511/riestech.v2i04.81.

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: Businesses should never stop trying to include every employee in their operations and never skimp on safety precautions. One of the safety methods in the worker-centered approach implementation is the significance of ergonomics. Typically, material handling phases in production processes include physical labor that demands a lot of operator effort. Handling objects by hand raises the possibility of workplace mishaps, which can lead to musculoskeletal injuries. This study focuses on the different labor postures used for gathering, transferring, and positioning waste as well as the manual hand
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15

Ankita Sappa. "Adaptive Machine Learning Algorithms for Anomaly Detection in Enterprise IT Infrastructure." Research Briefs on Information and Communication Technology Evolution 9 (December 30, 2023): 206–27. https://doi.org/10.69978/rebicte.v9i.201.

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The increasing scale and complexity of enterprise IT infrastructures renders traditional rule-based and static anomaly detection systems that are automated as well as manual, incapable of dealing with evolving threats, system dynamics, and concept drift. This paper proposes an adaptable Machine Learning (ML) architecture which can autonomously detect real-time anomalies within critical IT environments, including network, application, and host systems. By employing ensemble learning, streaming models, and drift-aware system architectures, the system detection performance degradation with regard
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16

Beyer, Andrea R., Lauren VieBrock, Kyle G. Rodino, et al. "Orientia tsutsugamushi Strain Ikeda Ankyrin Repeat-Containing Proteins Recruit SCF1 Ubiquitin Ligase Machinery via Poxvirus-Like F-Box Motifs." Journal of Bacteriology 197, no. 19 (2015): 3097–109. http://dx.doi.org/10.1128/jb.00276-15.

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ABSTRACTA rising theme among intracellular microbes is the delivery of ankyrin repeat-containing effectors (Anks) that interact with target proteins to co-opt host cell functions.Orientia tsutsugamushi, an obligate intracellular bacterium and the etiologic agent of scrub typhus, encodes one of the largest Ank repertoires of any sequenced microorganism. They have been previously identified as type 1 secretion system substrates. Here,in silicoand manual sequence analyses revealed that a large proportion ofO. tsutsugamushistrain Ikeda Anks bear a eukaryotic/poxvirus-like F-box motif, which is kno
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17

Kumar Tiwari, Manoj, Deepak P. Prabhu, and Akshay Chavan. "Design of an Indigenously Developed Patient Transfer Assistive Device." International Journal of Health Sciences and Research 13, no. 4 (2023): 62–72. http://dx.doi.org/10.52403/ijhsr.20230410.

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The patient transfer has always been challenging, usually requiring a number of caregivers to perform this task together, which is time-consuming and can easily cause secondary injuries to the patient. In addition, when the world is in the distressing predicament of a global pandemic covid-19, the issue of patient transfer is even more critical, as caregivers are at a high risk of infection, causing significant damage to healthcare resources. The goal of using assistive devices is to minimize the risk of injury. A lifting device is an assistive device that allows patients in hospitals, nursing
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18

Gaetán, S., M. Madia, and R. Cepeda. "First Report of Fusarium Crown and Root Rot Caused by Fusarium solani on St. John's-Wort in Argentina." Plant Disease 88, no. 9 (2004): 1050. http://dx.doi.org/10.1094/pdis.2004.88.9.1050b.

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Since 2001, 15 to18% of commercial plantings of the medicinal plant St. John's-wort (Hypericum perforatum L.) in Buenos Aires Province, Argentina were affected by a new disease. Disease symptoms of crown and root rot, wilting, chlorosis, and necrosis of the leaves appeared in circular-to-irregular shaped sectors of 12- to 14-month-old plants. Symptoms began with foliage turning yellow followed by an irregular, brown necrosis of the leaf margins. Lesions coalesced to form large necrotic areas causing a severe defoliation of the basal and upper leaves. A soft rot affected the crown and roots cau
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19

Cuypers, Bart, Franck Dumetz, Pieter Meysman, et al. "The Absence of C-5 DNA Methylation in Leishmania donovani Allows DNA Enrichment from Complex Samples." Microorganisms 8, no. 8 (2020): 1252. http://dx.doi.org/10.3390/microorganisms8081252.

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Cytosine C5 methylation is an important epigenetic control mechanism in a wide array of eukaryotic organisms and generally carried out by proteins of the C-5 DNA methyltransferase family (DNMTs). In several protozoans, the status of this mechanism remains elusive, such as in Leishmania, the causative agent of the disease leishmaniasis in humans and a wide array of vertebrate animals. In this work, we showed that the Leishmania donovani genome contains a C-5 DNA methyltransferase (DNMT) from the DNMT6 subfamily, whose function is still unclear, and verified its expression at the RNA level. We c
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20

Ivory, John D., Akke Vellinga, James O'Gara, and Georgina Gethin. "A scoping review protocol to identify clinical signs, symptoms and biomarkers indicative of biofilm presence in chronic wounds." HRB Open Research 4 (November 23, 2021): 71. http://dx.doi.org/10.12688/hrbopenres.13300.2.

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Introduction: Wound healing is characterised by haemostatic, inflammatory, proliferative and remodelling phases. In the presence of comorbidities such as diabetes, healing can stall and chronic wounds may result. Infection is detrimental to these wounds and associated with poor outcomes. Wounds are contaminated with microbes and debris, and factors such as host resistance, bacterial virulence, species synergy and bioburden determine whether a wound will deteriorate to critically colonised/infected states. Biofilms are sessile microbial communities, exhibiting high-level antibiotic tolerance an
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Ivory, John D., Akke Vellinga, James O'Gara, and Georgina Gethin. "A scoping review protocol to identify clinical signs, symptoms and biomarkers indicative of biofilm presence in chronic wounds." HRB Open Research 4 (July 8, 2021): 71. http://dx.doi.org/10.12688/hrbopenres.13300.1.

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Introduction: Wound healing is characterised by haemostatic, inflammatory, proliferative and remodelling phases. In the presence of comorbidities such as diabetes, healing can stall and chronic wounds may result. Infection is detrimental to these wounds and associated with poor outcomes. Wounds are contaminated with microbes and debris, and factors such as host resistance, bacterial virulence, species synergy and bioburden determine whether a wound will deteriorate to critically colonised/infected states. Biofilms are sessile microbial communities, exhibiting high-level antibiotic tolerance an
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Drakulic, Jassy, Olubukola Ajigboye, Ranjan Swarup, Toby Bruce, and Rumiana V. Ray. "Aphid Infestation Increases Fusarium langsethiae and T-2 and HT-2 Mycotoxins in Wheat." Applied and Environmental Microbiology 82, no. 22 (2016): 6548–56. http://dx.doi.org/10.1128/aem.02343-16.

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ABSTRACTFusarium langsethiaeis a fungal pathogen of cereal crops that is an increasing problem in northern Europe, but much of its epidemiology is poorly understood. The species produces the mycotoxins T-2 and HT-2, which are highly toxic. It was hypothesized that grain aphids,Sitobion avenae, may transmitF. langsethiaeinoculum between wheat plants, and a series of transmission experiments and volatile chemical analyses was performed to test this. Manual translocation of aphids from inoculated to uninfected hosts resulted in pathogen DNA accumulation in hosts. However, the free movement of win
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Bezerra, Vitor Hugo, Victor Guilherme Turrisi da Costa, Sylvio Barbon Junior, Rodrigo Sanches Miani, and Bruno Bogaz Zarpelão. "IoTDS: A One-Class Classification Approach to Detect Botnets in Internet of Things Devices." Sensors 19, no. 14 (2019): 3188. http://dx.doi.org/10.3390/s19143188.

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Internet of Things (IoT) devices have become increasingly widespread. Despite their potential of improving multiple application domains, these devices have poor security, which can be explored by attackers to build large-scale botnets. In this work, we propose a host-based approach to detect botnets in IoT devices, named IoTDS (Internet of Things Detection System). It relies on one-class classifiers, which model only the legitimate device behaviour for further detection of deviations, avoiding the manual labelling process. The proposed solution is underpinned by a novel agent-manager architect
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Yu, Yunqing, Shuisheng Xu, Mei Wang, and Qiang Xie. "Research and Development of a Multi-Point High-Precision Displacement Measuring System for the Installation Space of Vibration Isolation on Submarine Raft Structures." Applied Sciences 13, no. 21 (2023): 12024. http://dx.doi.org/10.3390/app132112024.

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The well installed status of raft vibration isolation is undoubtedly of great significance in marine engineering, especially for submarines. To achieve this, the accurate measurement of the installation space of the vibration isolation is necessary. The traditional measuring technique has many drawbacks. Therefore, simultaneously measuring the multi-point spacing with high precision between two metal surfaces is the focus of this work. Based on eddy current sensing principle, a multi-point spacing measuring system with a simple structure and good measurement accuracy has been developed and rep
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Fitria Ekawati, Iga, and Latipah. "Implementasi Metode Topsis pada Sistem Penunjang Keputusan Pemilihan Wedding Venue." Jurnal Informatika Polinema 7, no. 2 (2021): 103–8. http://dx.doi.org/10.33795/jip.v7i2.388.

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To prepare for the wedding, it takes energy and enough time for the program to work as it wishes. The dream of having a beautiful and exciting wedding is every couple's dream. Surabaya was one of the towns with the heavy population. Surabaya was one of the towns with the heavy population. Such conditions are problematic because if couples who are going to celebrate the wedding don't have enough land to host a wedding venue in Surabaya. Gathering information regarding a wedding venue takes a long time. On the question of obtaining it, a wedding venue customization system was developed to make i
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Kaushal, Ankit, Narinder Yadav, Nikhil Kumar, Sachin Yadav, Ishdeep Singla, and Dipanshu Garg. "Vehicle Number Plate Detection and Recognition." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 10 (2024): 1–5. http://dx.doi.org/10.55041/ijsrem38303.

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Real-time traffic monitoring systems face a host of challenges, especially the conventional methods using expensive labour- intensive and time-consuming manual operations . These traditional techniques generally involve human operators and hence are bound by scalability and efficiency. However, with advances in surveillance technology and computer vision, new prospects became possible . Through the incorporated video feeds coming from security cameras and traffic monitoring systems, detection oftraffic flow, counting, and analyzing the behavioural patterns of the numbered plates can be realize
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L., Nagaraja. "LIVING AND ECONOMIC CONDITIONS IN SLUMS – A CASE STUDY IN BANGALORE CITY." Shanlax International Journal of Arts, Science and Humanities 6, S2 (2019): 40–42. https://doi.org/10.5281/zenodo.2572946.

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An attempt has been made here to examine the nature of interconnection and the process of interaction across urbanization, proliferation of slums and its impact on the urban environment. One of the inevitable and almost unavoidable social consequences of urbanization and industrialization has been the unabated proliferation of slums accompanied by environmental degradation among much else. One of the most persistent reasons for the unabated growth of slums which started spreading to medium towns and small towns is rural-urban migration, which is in turn caused by factors referred to as &lsquo;
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Chaffin, Don B. "A Biomechanical Basis for Low Back Injury Risk in High Exertion Tasks." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 49, no. 14 (2005): 1344–48. http://dx.doi.org/10.1177/154193120504901417.

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Manual work is still very prevalent in many jobs today. This paper will explore the historic role that biomechanics has played in understanding these outcomes, as well as reviewing various prevention strategies used today. The focus of the presentation will be on occupational low back pain. The discussion begins with the fundamental biomechanical reality; that the lumbar spine is often subjected to extremely large compression forces when one stoops to pick up an object, even if the object is of moderate weight. The paper will discuss this outcome, as well as biomechanics research in the late 8
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El Sehmawy, Asmaa, Shaimaa Abd Elaziz, Fatma Elzhraa Diab, et al. "Assessment of the natural killer cell, IFN-ƒ× and IL-10 blood levels in children with attention-deficit/hyperactivity disorder." Egyptian journal of Immunology 30, no. 03 (2023): 13–22. http://dx.doi.org/10.55133/eji.300302.

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder, affects millions of youngsters and typically persists into adulthood. The pathophysiology of ADHD may be due to an impaired immune response, common genetics, and environmental linkages, as all have been suggested as potential underlying mechanisms for ADHD. During systemic inflammation, natural killer (NK) cells can produce pro-inflammatory cytokines like interferon (IFN- g) and anti-inflammatory cytokines like interleukin (IL-10); this demonstrates the importance of both of their roles as regulators to counterac
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Ibrahimova, S. "ABOUT THE TEACHING OF ENERGY MACHINES AND TRANSPORTATION MACHINES APPLIED IN VARIOUS FIELDS OF NATIONAL ECONOMY IN TECHNOLOGY CLASSES." Scientific heritage, no. 150 (December 11, 2024): 80–87. https://doi.org/10.5281/zenodo.14378802.

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In modern times, the technology subject program (curriculum) serves the develop ment of the technological thinking of students of general education schools, the for mation of technological skills in them, and the acquisition of necessary knowledge to continue their education in the next stages. In the article, the structure and opera tion status of energy machines taught in high school is explained, the types of machi nes, their importance and how to facilitate human labor are noted. It is also explained in those lessons that transport and power machines play a key role in many heavy and light
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Chang, Lauren A., Raveen Rathnasinghe, Sonia Jangra, Angela Choi, Adolfo García-Sastre, and Michael Schotsaert. "Vaccination modulates pulmonary eosinophil subsets upon breakthrough influenza infection." Journal of Immunology 208, no. 1_Supplement (2022): 126.02. http://dx.doi.org/10.4049/jimmunol.208.supp.126.02.

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Abstract Eosinophils play a critical role in mucosal tissue homeostasis, anti-helminth responses, and allergy. Lung eosinophilia is associated with aberrant T cell responses to respiratory viral infection and is also a consequence of vaccine-associated enhanced respiratory disease (VAERD). A growing body of literature has demonstrated there are different phenotypic subsets of eosinophils and, depending on subset, can play a protective role and aid in lung recovery following infection. Previous work by Choi et al. showed recruitment of eosinophils to the lung in BALB/c mice vaccinated with alum
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Calderon, Ariel, James Griffin, and Juan Cristóbal Zagal. "BeamMaker: an open hardware high-resolution digital fabricator for the masses." Rapid Prototyping Journal 20, no. 3 (2014): 245–55. http://dx.doi.org/10.1108/rpj-01-2013-0006.

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Purpose – The democratization of invention is a long lasting desire for the advancement of society. Having access to education and the means of production appears as the major factors for the implementation of this goal. 3D printing is a revolutionary technology that has the potential to bring digital manufacturing to everyone. However, the rise of personal fabrication requires an increase in printing quality, a reduction on machine cost and an increase in knowledge shared by the open hardware community. The purpose of this paper is to explore the development of a new Open Hardware printer pro
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Grant, Alex, and Colm O'Dwyer. "Thickness-Based Dispersion in Opal Photonic Crystals." ECS Meeting Abstracts MA2022-02, no. 36 (2022): 1304. http://dx.doi.org/10.1149/ma2022-02361304mtgabs.

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Photonic crystals (PhCs) are types of colloidal crystals which demonstrate a host of exciting optical phenomena, the nature of which can lend insight into their structure and enable a range of potential applications in fields such as optics and optoelectronics,1 energy storage,2-6 and sensors for environmental monitoring, biomedicine and food preservation.7 Artificial opals8 are PhCs which can be formed easily using low-cost self-assembly methods and their structures are composed of highly ordered, close-packed, polymeric sphere arrays. While the optical behaviour of opals has received signifi
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Bortone, Dante, Steven Vensko, Sarah Entwistle, et al. "75 Generalizability of potential biomarkers of response to CTLA-4 and PD-1 blockade therapy in cancer." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A81—A82. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0075.

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BackgroundMultiple genomics-based biomarkers of response to immune checkpoint inhibition have been reported or proposed, including tumor mutation/neoantigen frequency, PD-L1 expression, T cell receptor repertoire clonality, interferon gene signature expression, HLA expression, and others.1 Although genomics associations of response have been reported, the primary studies have used a variety of data generation and processing techniques. There is a need for data harmonization and assessment of generalizability of potential biomarkers across multiple datasets.MethodsWe acquired patient-level RNA
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Anasse, NOUNSI, OUTCOUMIT Ali, TALBI Zouheir, et al. "Effect of endomycorrhizal inoculation on the growth of Eucalyptus plants." Biolife 3, no. 3 (2022): 583–94. https://doi.org/10.5281/zenodo.7272865.

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<strong>ABSTRACT</strong> The aim of this work is to study the effect of a composite endomycorrhizal inoculum on growth of Eucalyptus plants (<em>E. gomphocephala</em>) in the nurseries conditions. Analysis of the results, four months after inoculation, revealed that all roots were mycorrhizal and different structures characterizing arbuscular endomycorrhizal fungi were observed. The mycorrhizal frequency and intensity of Eucalyptus roots are 90 and 25% respectively. This roots endomycorrhization was accompanied by a significant improvement on growth parameters of mycorrhized Eucalyptus plants
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Guven, Gursans, and Esin Ergen. "Tracking major resources for automated progress monitoring of construction activities: masonry work case." Construction Innovation ahead-of-print, ahead-of-print (2021). http://dx.doi.org/10.1108/ci-05-2020-0081.

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Purpose The purpose of this study is to monitor the progress of construction activities in an automated way by using sensor-based technologies for tracking multiple resources that are used in building construction. Design/methodology/approach An automated on-site progress monitoring approach was proposed and a proof-of-concept prototype was developed, followed by a field experimentation study at a high-rise building construction site. The developed approach was used to integrate sensor data collected from multiple resources used in different steps of an activity. It incorporated the domain-spe
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Oliveira, Jordana Inácio Nascimento, and Nicolas Corradi. "Strain-specific evolution and host-specific regulation of transposable elements in the model plant symbiont Rhizophagus irregularis." G3: Genes, Genomes, Genetics, March 20, 2024. http://dx.doi.org/10.1093/g3journal/jkae055.

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Abstract Transposable elements (TEs) are repetitive DNA that can create genome structure and regulation variability. The genome of Rhizophagus irregularis, a widely studied arbuscular mycorrhizal fungus (AMF), comprises approximately 50% repetitive sequences that include transposable elements. Despite their abundance, two-thirds of TEs remain unclassified, and their regulation among AMF life stages remains unknown. Here, we aimed to improve our understanding of TE diversity and regulation in this model species by curating repeat datasets obtained from chromosome-level assemblies and by investi
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Schoelmerich, Marie C., Heleen T. Ouboter, Rohan Sachdeva, et al. "A widespread group of large plasmids in methanotrophic Methanoperedens archaea." Nature Communications 13, no. 1 (2022). http://dx.doi.org/10.1038/s41467-022-34588-9.

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AbstractAnaerobic methanotrophic (ANME) archaea obtain energy from the breakdown of methane, yet their extrachromosomal genetic elements are little understood. Here we describe large plasmids associated with ANME archaea of the Methanoperedens genus in enrichment cultures and other natural anoxic environments. By manual curation we show that two of the plasmids are large (155,605 bp and 191,912 bp), circular, and may replicate bidirectionally. The plasmids occur in the same copy number as the main chromosome, and plasmid genes are actively transcribed. One of the plasmids encodes three tRNAs,
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Winkler, Andreas. "Structuring astral science." Manuscript and Text Cultures (MTC) 2, no. 1 (2023). http://dx.doi.org/10.56004/v2.1aw.

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Papyrus Berlin 8345, which comes from the Roman-period Fayum (Egypt), contains a Demotic astrological treatise aimed at foretelling an individual’s future based on the positions of the seven celestial bodies known in antiquity (Sun, Moon, Saturn, Jupiter, Mars, Venus, and Mercury) in the twelve places or compartments of the zodiac known as the dodecatropos. This paper briefly outlines the contents of the text and considers the conventions of textual division demonstrated in the papyrus. Since Demotic lacks modern punctuation, the scribe employed a host of other techniques to highlight and diff
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Garcia, Arman C., Michael Shavlik, Michael J. Harms, and Michael Dwight Pluth. "Structural Deformations in Cucurbit[n]urils: Analysis, Host‐Guest Dependence, and Automated Ellipticity Measurements using ElliptiCB[n]." Chemistry – A European Journal, August 13, 2024. http://dx.doi.org/10.1002/chem.202401981.

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Cucurbit[n]urils (CB[n]s) are cyclic macrocycles with rich host‐guest chemistry. In many cases, guest binding in CB[n]s results in structural deformations. Unfortunately, measuring such deformations remains a major challenge, with only a handful of manual estimations reported in the literature. To address this challenge, we have developed the public program ElliptiCB[n], which is available on GitHub, that provides a robust and automated method for measuring the elliptical deformations in CB[n] hosts. We outline the development and validation of this approach, apply ElliptiCB[n] to measure to t
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Orozco-Arias, Simon, Pío Sierra, Richard Durbin, and Josefa González. "MCHelper automatically curates transposable element libraries across eukaryotic species." Genome Research, December 9, 2024. https://doi.org/10.1101/gr.278821.123.

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The number of species with high-quality genome sequences continues to increase, in part due to the scaling up of multiple large-scale biodiversity sequencing projects. While the need to annotate genic sequences in these genomes is widely acknowledged, the parallel need to annotate transposable element (TE) sequences that have been shown to alter genome architecture, rewire gene regulatory networks, and contribute to the evolution of host traits is becoming ever more evident. However, accurate genome-wide annotation of TE sequences is still technically challenging. Several de novo TE identifica
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Dong, Yufeng, Xianyun Tian, Ziyang Zhu, and Xuening Wang. "Exploring Features, Customer Emotions, and Evaluations of Airbnb Online Experiences: A Framework for Virtual Tourism Experiences." International Journal of Tourism Research 27, no. 3 (2025). https://doi.org/10.1002/jtr.70068.

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ABSTRACTThis study proposes a conceptual framework grounded in the Stimulus‐Organism‐Response theory (S‐O‐R) to investigate the relationship between virtual tourism experience features, customer emotions, and their evaluations. Through a hybrid approach combining automated aspect extraction and manual annotation, five key features of online experiences (OEs) are identified: host attributes, activity design and experiential value, technology and technical tools, value for money, and personalization. Leveraging deep learning‐based emotion analysis, the research maps customer emotional states alo
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Humphrey, Suzanne, Angeliki Marouli, Katja Thümmler, Margaret Mullin, Leighton Pritchard, and Daniel M. Wall. "Genomic characterization of prophage elements in Clostridium clostridioforme: an understudied component of the intestinal microbiome." Microbiology 170, no. 8 (2024). http://dx.doi.org/10.1099/mic.0.001486.

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Genome sequencing of Clostridium clostridioforme strain LM41 revealed the presence of an atypically high proportion of mobile genetic elements for this species, with a particularly high abundance of prophages. Bioinformatic analysis of prophage sequences sought to characterize these elements and identify prophage-linked genes contributing to enhanced fitness of the host bacteria in the dysbiotic gut. Using PHASTER, PhageScope and manual curation, this work has identified 15 prophages: 4 predicted to be intact, 2 predicted to be defective and 9 which are unclassified. Quantitative PCR (qPCR) an
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Mather, Michael W., Steven Powell, Benjamin Talks, et al. "Dysregulation of immune response in otitis media." Expert Reviews in Molecular Medicine 23 (2021). http://dx.doi.org/10.1017/erm.2021.10.

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Abstract Objective Otitis media (OM) is a common reason for children to be prescribed antibiotics and undergo surgery but a thorough understanding of disease mechanisms is lacking. We evaluate the evidence of a dysregulated immune response in the pathogenesis of OM. Methods A comprehensive systematic review of the literature using search terms [otitis media OR glue ear OR AOM OR OME] OR [middle ear AND (infection OR inflammation)] which were run through Medline and Embase via Ovid, including both human and animal studies. In total, 82 955 studies underwent automated filtering followed by manua
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Valera, B., R. Nava, and E. Miranda. "An autonomous system for linear and angular measurements in big surfaces." Journal of Applied Research and Technology 2, no. 02 (2004). http://dx.doi.org/10.22201/icat.16656423.2004.2.02.581.

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At present, warehouse construction industry makes large vertical stores over small areas causing vertical designs of vehicles and structures. In this situation, the floor must have constant levelness and high flatness in order to achieve the nominal performance of the very narrow aisle lift trucks. With this in mind, in this paper we present a novel system for levelness and flatness measurement based on big surfaces shape measurement. The system has linear and angular optical measurement devices on a mobile robot with automatic drive based on an embedded microcontroller. Readings from the robo
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Iraola, Gregorio, Lucía Spangenberg, Bruno Lopes Bastos, et al. "Transcriptome Sequencing Reveals Wide Expression Reprogramming of Basal and Unknown Genes in Leptospira biflexa Biofilms." mSphere 1, no. 2 (2016). http://dx.doi.org/10.1128/msphere.00042-16.

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ABSTRACT In this work, we describe the first transcriptome based on RNA-seq technology focused on studying transcriptional changes associated with biofilm growth in a member of the genus Leptospira. As many pathogenic species of this genus can survive inside the host but also persist in environmental water, mostly forming biofilms, identifying the molecular basis of this capacity can impact the understanding of how leptospires are able to fulfill a complete life cycle that alternates between adaptation to the host and adaptation to hostile external environmental conditions. We identified sever
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Nguyen, Tuan Hoa, Thanh Nhan Nguyen, Anh Huy Vo, Minh Tuan Nguyen, and Thinh Quang Ngo Ha. "Research on remotely monitoring controller for the drying process of fruit." Science & Technology Development Journal - Engineering and Technology, 2022. http://dx.doi.org/10.32508/stdjet.v5i2.967.

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In the field of agriculture, the conservation of the agricultural products plays a vital role. The challenge in this topic is to manage a large scale of storehouse by manual works. Therefore, an implementation of IoT-based controller for monitoring in preserving fruits such as dragon fruit or jackfruit as a remotely monitored solution. First of all, the analysis of hardware platform and software programming is completed in this work. Several peripheral devices must be deployed in order to send or receive data online. Some sensing boards are also suggested to measure the physical variables such
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Dewaele, Klaas, Peter Odhiambo, Lieve Vermeiren, Jan Van Den Abbeele, and Pieter Monsieurs. "Unravelling the miRNA Landscape in Tsetse Fly Saliva and Salivary Glands During Trypanosoma brucei Infections." NAR Molecular Medicine, July 11, 2025. https://doi.org/10.1093/narmme/ugaf025.

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Abstract MicroRNAs (miRNAs) are emerging as potential mediators of cross-species gene regulation in vector-borne diseases. Using small RNA-sequencing, this study investigated the presence of miRNAs in the tsetse fly (Glossina morsitans)-trypanosome parasite system, focusing on the fly's salivary glands and saliva during Trypanosoma brucei infections. To ensure annotation accuracy, we implemented a robust pipeline incorporating de novo prediction, comparative analyses and manual curation to minimize false positives. This resulted in the detection of 54 unique miRNAs in tsetse saliva and salivar
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Cahuantzi, Roberto, Katrina A. Lythgoe, Ian Hall, Lorenzo Pellis, and Thomas House. "Unsupervised identification of significant lineages of SARS-CoV-2 through scalable machine learning methods." Proceedings of the National Academy of Sciences 121, no. 12 (2024). http://dx.doi.org/10.1073/pnas.2317284121.

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Since its emergence in late 2019, SARS-CoV-2 has diversified into a large number of lineages and caused multiple waves of infection globally. Novel lineages have the potential to spread rapidly and internationally if they have higher intrinsic transmissibility and/or can evade host immune responses, as has been seen with the Alpha, Delta, and Omicron variants of concern. They can also cause increased mortality and morbidity if they have increased virulence, as was seen for Alpha and Delta. Phylogenetic methods provide the “gold standard” for representing the global diversity of SARS-CoV-2 and
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Case, Nicola T., Johannes Westman, Michael T. Hallett, et al. "Respiration supports intraphagosomal filamentation and escape of Candida albicans from macrophages." mBio, December 2023. http://dx.doi.org/10.1128/mbio.02745-23.

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ABSTRACT For the human fungal pathogen Candida albicans , metabolic flexibility and the ability to transition between yeast and filamentous growth states are key virulence traits that enable disease in the host. These traits are particularly important during the interaction of C. albicans with macrophages, where the fungus must utilize multiple alternative carbon sources to survive after being phagocytosed, and filamentation is coupled to fungal escape and immune cell death. Here, we employed functional genomic screening of conditional-expression mutants covering &gt;50% of the C. albicans gen
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