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Souza, Miriam Coelho de. "Magnesium supplementation in treatment of premenstrual syndrome." Thesis, University of Reading, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363772.
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Canning, Sarah Elizabeth. "The premenstrual syndrome : characterisation, diagnosis and treatment." Thesis, University of Leeds, 2008. http://etheses.whiterose.ac.uk/622/.
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Premenstrual syndrome (PMS) is a prevalent condition. Key symptoms which promote treatment seeking are primarily psychological e. g. depression and aggression. Sufferers are often reluctant to take prescribed medication and often purchase dietary supplements and herbal remedies over the counter for which the evidence base with regards efficacy is limited. The primary aim of this thesis was to examine the effectiveness of St. John's Wort (SJW) for PMS. Proposals that this herbal remedy could benefit PMS symptoms are based on evidence that SJW increases serotonin levels and suppresses pro-inflammatory cytokine production. Following a systematic review which demonstrated that although calcium and continuous vitamin B6 administration confer some benefit for premenstrual symptoms, the evidence for most dietary supplements and herbal remedies including SJW is conflicting or insufficient, a ten-cycle randomised double-blind, placebocontrolled, crossover trial was conducted. PMS sufferers (NIMH, 1983) were administered 900mg SJW/day (0.18% hypericin; 3.38% hyperforin) for two menstrual cycles (n=34). SJW was found to benefit physical and behavioural PMS symptoms, but did not significantly improve mood or pain symptoms. A comparison of various commonly used analytical strategies performed on the data highlighted the need for a consensus to be reached regarding the way in which researchers assess treatment efficacy. Hormone (FSH, LH, oestradiol, progesterone, prolactin and testosterone) and cytokine (IL-1p, IL-6, IL-8, IFN-y and TNF-a) levels were assessed in women with and without PMS during the follicular and luteal phases, and were also studied in PMS sufferers taking SJW and placebo treatment. The hormone and cytokine profiles of PMS sufferers during SJW and placebo treatment did not differ. However, PMS sufferers exhibited significantly greater testosterone and cytokine (IL-6,11-8 and TNF-a) levels than normally cycling women who did not self-report problematic PMS symptoms across the cycle, suggesting that these mechanisms may be involved in the aetiology of the syndrome. To ensure the scientific quality of the clinical trial, certain methodological considerations were explored. PMS is diagnosed in various ways, which has resulted in PMS studies being conducted on heterogeneous samples of women, who are often not analogous to women requiring treatment in clinical practice. This study highlighted the need for researchers to use a diagnostic procedure that identifies PMS sufferers experiencing PMS symptoms at a severity appropriate to address the aim of their study, and that differentiates women with PMS from those with clinical anxiety and depression. Moreover, the DSR (Freeman et al., 1996) was refactor analysed and a two factor solution was produced, the DSR-20. This new measure was shown to be a more sensitive tool than the original DSR to assess treatment effects in the sample recruited for this research. Collectively these findings could improve future diagnostic and therapeutic strategies.
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Kudlas, Jane Michele. "Low-fat diet vs. education support in the treatment of late luteal phase dysphoric disorder." Diss., Virginia Tech, 1992. http://hdl.handle.net/10919/39719.
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A treatment outcome study was conducted comparing a low-fat diet intervention with an education-support group and a waiting-list control group in the treatment of premenstrual tension syndrome (PMS) or Late Luteal Phase Dysphoric Disorder (LLPDD). Subjects met provisional diagnostic criteria for LLPDD and symptoms were monitored prospectively. A low-fat diet was hypothesized too be an effective intervention for reducing the severity of both physical and emotional symptoms in women suffering from LLPDD. This was based on the theory relating raised estrogen levels to premenstrual distress, and research suggesting low-fat diets reduce estrogen levels.
The hypothesis that a low-fat diet would decrease premenstrual suffering was not supported by the results of this study. However, there appeared to be an advantage to participating in a group which provided support and information on LLPDD compared to receiving no treatment. Implications for future research, treatment recommendations, and methodological issues are discussed.Ph. D.
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Magos, Adam Laszlo. "Diagnosis of the premenstrual syndrome, and treatment with subcutaneous crystalline implants of oestradiol." Thesis, King's College London (University of London), 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420878.
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Eriksson, Olle. "Studies on Premenstrual Dysphoria." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5812.
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Graham, Cynthia Anne. "Treatment of premenstrual syndrome with a triphasic oral contraceptive : a double-blind placebo-controlled trial." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74262.
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Two studies are presented which investigated the relationship between oral contraceptives (o.c.s) and premenstrual changes in mood and physical state. The retrospective pilot study examined possible differences in symptom-reporting between groups of pill-users and non-users. Women using o.c.s had lower severity scores on a number of physical and mood-related symptoms compared to non-users. In the prospective study, eighty-two women with complaints of moderate to severe premenstrual symptoms were recruited for a double-blind, controlled trial of a triphasic o.c. Subjects made daily ratings of symptoms for one to two baseline cycles and were then randomly assigned to receive either placebo or the o.c. for three treatment cycles. Prospective assessment of symptoms was made using a variety of measures, and circulating levels of estrogen and progesterone were measured at three points during the cycle. Bloating and breast pain showed a greater reduction in the o.c. group than in the placebo group. In a subgroup of women with premenstrual depressive change, the o.c. also produced greater improvement in a number of symptoms compared to placebo. For all other symptoms, there was no beneficial effect of the active treatment over placebo. Women who received o.c.s reported decreased sexual interest after starting the pill. Possible hormonal mechanisms for these effects are discussed.
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Frank, Beth. "Conjoint treatment : impact on married couples with and without PMS." Virtual Press, 1994. http://liblink.bsu.edu/uhtbin/catkey/917831.
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The goal of this study was to investigate the efficacy of a marital systems approach to the treatment of women with self-referred premenstrual syndrome. The first purpose of the study was to identify any significant differences on the Global Distress Scale of the Marital Satisfaction Inventory and the Causal Dimension Scale between (PMS+) and (PMS-) married couples before and after marital treatment. The second purpose of the study was to determine any significant differences on dependent measures of averaged marital ratings between (PMS+) and (PMS-) wives during thecycle ratings between (PMS+) and (PMS-) wives.Nine married couples participated in a group comparison study through Community Hospitals of Indianapolis, Indiana. The study was conducted in two phases, including a three month assessment phase followed by a two month treatment phase. Four married couples whose wives met the DSM-III-R's diagnostic criteria for Late Luteal Phase Dysphoric Disorder were included in the (PMS+) group. Five married couples whose wives did not meet the diagnostic criteria for LLPDD were included in the (PMS-) comparison group.Statistical analyses revealed significant time effects; assessment and treatment purpose of the study was differences on dependent phase of the study. The third to identify any significant measures of averaged menstrual no three-way or two-way interactive effects for any of the three hypotheses. The results clinically support the notion of treating marriages with PMS versus solely treating women with PMS. Regardless of whether wives prospectively confirmed premenstrual symptoms, treatment involving the marriage impacted menstrual cycle symptom ratings and perceptions of the marriage positively.Department of Counseling Psychology and Guidance Services
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Patel, Reshma. "The effect of the homeopathic simillium on white females suffering with symptoms of premenstrual syndrome using ten case studies." Thesis, 2011. http://hdl.handle.net/10210/3725.
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M.Tech.Premenstrual syndrome (PMS) is a group of physical and psychological symptoms that occur cyclically in females. It is of unknown aetiology. These symptoms occur specifically during the luteal phase (from day 14 to day 1 of the next menstrual cycle) and are resolved over the course or at the onset of menstruation (Indusekhar et al., 2007). The syndrome is characterised by irritability, depression, anxiety, headache, abdominal bloating, breast tenderness, breast swelling, changes in appetite, acne, and weight gain due to oedema. Mild physiological symptoms are experienced by approximately 95% of all women of reproductive age and about 5% of symptomatic women complain of extremely severe symptoms, called premenstrual dysphoric disorder (PMDD), that disrupt their daily living (Wyatt, 1999). Deuster et al., (1999) note that PMS is prevalent in all demographic groups, however differences in races do exist and their research shows that black women are more likely to suffer from PMS than women of other races. The current conventional treatment options are limited, not always effective and sometimes have significant side effects (Ross et al., 2000). Complementary and alternative treatments are said to be beneficial, however sufficient quality trials are required to substantiate their claims to efficacy (Indusekhar et al., 2007). Research into the use of individualised homeopathy in PMS has been shown to have positive results (Yakir et al., 2001). The aim of this four month study was to determine the efficacy of the homeopathic simillimum in the treatment of premenstrual syndrome in white females. This study will eventually provide the material to compare the presentation of PMS, and the effect of the homeopathic simillimum in different race groups. The following symptoms were evaluated 14 days before menstruation: irritability, depression, anxiety, headache, abdominal bloating, breast tenderness, breast swelling, and food cravings (Beers et al., 2003). Volunteers were asked to complete a selection questionnaire, in order for them to take part in the study. If they qualified to take part in this study a full case history was then taken for each participant using the standard homeopathic clinic case form. In this four month case study each of the ten participants completed a PMS chart for each month grading their symptoms on a daily basis and recording their dates of menstruation. A baseline of each participant’s premenstrual symptoms was established by an initial treatment-free month where a PMS chart had to be completed to score the participants’ daily symptoms. Thereafter the participants were treated using homeopathic simillimum treatment for the remaining three months. The chart required each participant to score the severity of the eight different premenstrual symptoms that they experience on a scale of 0 to 5 (0 indicated that the symptom was not present, and 5 indicated that the symptom was very severe). These charts were collected at the end of each cycle. At the end of the trial these PMS charts were submitted for statistical analysis. These results were analysed by using the non parametric Wilcoxon Signed Ranks Test by comparing the severity of symptoms experienced in the premenstrual period (14 days before menstruation) for each of the three months of treatment to the initial treatment-free month. These results showed that the homeopathic simillimum was statistically significant in the treatment of the symptoms of PMS in these white females.
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Komar, Tania. "A qualitative study to determine the efficacy of the homoeopathic similimum in the treatment of premenstrual syndrome." Thesis, 2009. http://hdl.handle.net/10210/2608.
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Sarawan, Shanie. "An evaluation of the efficacy of a homeopathic complex, Premenstron, in the treatment of premenstrual syndrome in terms of the patients' perception." Thesis, 2001. http://hdl.handle.net/10321/2173.
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Dissertation submitted in partial compliance with the Requirements for the Master's Degree in Technology: Homeopathy, Technikon Natal, 2001.The purpose of this double -blind placebo-control1ed study was to evaluate the efficacy of a homeopathic complex, Premenstron\xAE, in the treatment of premenstrual syndrome in terms of the patients' perception of the efficacy of the treatment. Thirty-four patients were selected from volunteers who met the diagnostic criteria developed by Dalton (1984: 19). Of these patients thirty completed the study. These patients were divided into two groups according to simple random sampling. Data was collected at the Homeopathic Day Clinic at Technikon Natal. Half of the patients received a placebo and the other half received the homeopathic complex. Patients were treated over a period of approximately two months (three consultations ). The patients completed the Moos Menstrual Distress Questionnaire at each consultation. The questionnaire consists of 47 symptoms grouped into eight subscales. Results were analysed statistically using the Mann Whitney unpaired test (inter-group comparison) and the Wilcoxon's sign rank test (intra-group comparison). When the three questionnaires for each patient were compared, it was found that the placebo group did improve in the second consultation (P= 0.016) but the placebo effect did not last through to the third consultation. The treatment group
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Laister, Carrie-Ann. "The efficacy of homoeopathic simillimum in the treatment of premenstrual syndrome (PMS)." Thesis, 2008. http://hdl.handle.net/10321/383.
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Thesis (M.Tech.: Homoeopathy)--Durban University of Technology, 2008This study was intended to evaluate the efficacy of homoeopathic simillimum in the treatment of premenstrual syndrome (PMS). The sample group consisted of women between the ages of eighteen and forty, living in the greater Durban area. PMS is a condition characterized by nervousness, irritability, anxiety, depression, and possibly headaches, oedema, and mastalgia, occurring during the 7 to 10 days before and usually disappearing a few hours after the onset of menses (Beers and Berkow, 1999:1932-1933). 75% of all women suffer from PMS to some degree (Hayman, 1996). A total of 39 participants with PMS were selected for the study on the basis of inclusion and exclusion criteria (Chapter 3). Participants were randomly divided into 2 groups (treatment and placebo) according to the randomisation sheet. There were 12 withdrawals from the study. 27 of the participants completed the study of which, 14 were on placebo treatment and 13 on active treatment. The treatment followed the initial consultation, which consisted of 3 powders containing either active ingredient (i.e. simillimum) or matching placebo and a 20ml bottle of liquid containing either active ingredient or placebo. Each participant was required to take one powder daily for three days from day 10 of their menstrual cycle followed by liquid treatment daily till onset of menstruation. Each participant had 3 consultations with the researcher over a 3 month period; each consultation a month apart. Menstrual Distress Questionnaires (Appendix A) were completed by the participants at each consultation. The data accumulated via the questionnaires was evaluated using non-parametric tests and analyzed statistically using the Wilcoxon’s Signed rank iv test and the Kruskal Wallis test. The results were analysed at a 95% confidence rating with p ≤ 0.05. Data was analysed using the SPSS (version 15.1 ®) for Windows ® statistical software suite. The intra-group analysis showed statistically significant changes in the subgroups of water retention (p=.020) and appetite changes (p=.010) in the Treatment Group. The Placebo Group showed statistical significant changes in the subgroups of concentration (p=.029), autonomic reaction (p=.013) and appetite changes (p=.035). The inter-group analysis failed to reveal any statistical significance. Therefore, the conclusion is that homoeopathic simillimum was not effective in the treatment of premenstrual syndrome (PMS). There were clinical improvements noted by participants during the study which suggest that more research into the treatment of PMS should be conducted. Studies with a larger sample group over a longer time frame with daily outcome measures would give a better indication of the efficacy of the homoeopathic simillimum on premenstrual syndrome.
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Mudzanani, Mainganye Lydo. "Case studies on the effect of the homoeopathic similimum in black females with premenstrual syndrome." Thesis, 2012. http://hdl.handle.net/10210/4815.
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M.Tech.Premenstrual syndrome affects millions of premenopausal women and has been described as one of the most common disorders in women. Premenstrual syndrome (PMS) is defined as the cyclic recurrence of symptoms such as anxiety, depression, food cravings, bloating, breast tenderness, and headaches during the luteal phase (from day fourteen to day one) of the menstrual cycle (Nel, 1995). PMS has been estimated to affect 75% of women of reproductive age, and there are no optimal conventional treatment options available (Steiner et al., 2006). Research has found an increased incidence of PMS in black women (Deuster et al., 1999). Due to the high number of women suffering from PMS and side-effects of conventional medicine, a safe alternative treatment for PMS is required. The homoeopathic similimum method involves prescribing one remedy at a time in optimal potency and repetition based on the totality of the individual patient’s mental, emotional and physical symptoms (Vithoulkas, 1985).
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Sukati, Behlulile Nonsikelelo Stoppy. "The efficacy of a homoeopathic mother tincture complex (Vitex agnus castus, Melissa officinalis and Valeriana officinalis) in the management of premenstrual dysphoric disorder." Thesis, 2018. http://hdl.handle.net/10321/3060.
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Submitted in partial fulfillment of the requirements for the Degree of Master of Technology in Homoeopathy, Durban University of Technology, Durban, South Africa, 2018.Research Problem Statement Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome (PMS) that involves a combination of emotional and physical symptoms that result in significant functional impairment. PMDD can be debilitating and there are multiple treatment options available, but these are not without side effects. Although complimentary or alternative medicine may be beneficial in treating PMDD, however, there is not enough data available to validate their effectiveness. This study aimed at comparing and determining the efficacy of a homoeopathic mother tincture complex (Vitex agnus castus, Melissa officinalis and Valeriana officinalis) compared to placebo in the management of PMDD. Methodology A sample size of 30 consenting female participants with PMDD who met the inclusion criteria as set out in the Diagnostic and Statistical Manual of Mental Disorders. The duration of the study was three months for each participant. Participants were randomly divided into experimental and placebo groups with three consultations over the study period where Kessler Psychological Distress Scale and Visual Analogue Scale were applied. Non-parametric and inferential analysis of data were performed to analyse and compare the effects of treatment and time on symptoms over the three consultation periods (α.05). Results Results for both scales showed no statistical significance in the interaction between time and treatment. The results showed no statistical differences between the control and experimental group in the management of PMDD. However, the mean value measured in the experimental group were consistently lower than the control. Conclusion The conclusion derived from this study is that the homoeopathic complex studied is not effective in the treatment of PMDD. None of the results showed significant differences between the treatment and the placebo group trials. Further studies are highly recommended in this field.
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Davidson, Tanith Emily. "The effect of Sutherlandia frutescens 200CH on CD4 and symptomatology in persons with the human immunodeficiency virus syndrome." Thesis, 2012. http://hdl.handle.net/10210/7321.
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M.Tech.Since its discovery in 1983, millions of people worldwide have been infected with the human immunodeficiency virus (HIV). HIV is a singlestranded retrovirus belonging to the Lentivirinae subfamily of retroviruses and is responsible for the acquired immune deficiency syndrome (AIDS) (Haslett et al, 2002). The infection results in a wide range of clinical manifestations related to defective cell-mediated immunity (Beers and Berkow, 1999). At the end of the twentieth century, over 21 million individuals worldwide had died from AIDS, over 34 million were living with the HIV infection, and over 95% of HIV-infected persons resided in developing nations (Klatt, 2005). At present, 40 million people worldwide are infected with HIV/AIDS of which more than 26 million reside in Africa (Treatment Access, 2005). Sutherlandia frutescens, a medicinal plant from South Africa has documented anti-cancer and antiviral activity. One of the active compounds of this plant is L-canavanine, a cytokine-inducible nitric oxide synthase (iNOS) inhibitor (Van Wyk and Gericke, 2000). In minute doses, the iNOS inhibitor may stimulate nitric oxide (NO) release to counteract retrovirus replication. This study aimed to ascertain the effect of Sutherlandia frutescens 200CH on CD4 cell counts and symptomatology in persons infected with HIV. Study parameters involved recording of vital signs, symptomatology and CD4 analysis at three separate consultations over a ten-week period. All information was collected and collated for statistical or descriptive analysis. The research study was carried out on a random sample size of twenty-six participants, between the age of seventeen and fifty years over a period of ten weeks. Participants included both genders and had been previously diagnosed HIV-positive. Persons using antiretroviral treatment or falling into Category C as specified in the Centres for Disease Control Classification (Appendix B), were excluded from the sample group. Participants acted as own controls for the study with the use of a CD4 analysis baseline reading at the first consultation. Participants were then assessed at mid-term (week 5) and final consultations (week 10) during the study. Sutherlandia frutescens 200CH, in granule form, was taken sublingually once a day for two weeks, with participants then taking no medication for three weeks until the mid-term consultation. The treatment regimen was repeated in the second half of the study. Physical examinations to assess vital signs and opportunistic infections, completion of a health status questionnaire and report-back sessions were conducted at all consultations to determine a general symptomatic picture of research participants. Blood samples taken at all consultations were analysed for CD45+ white cell count, CD4 percentage of lymphocytes and absolute CD4 cell count. The McNemar test and a One Factor Repeated Measure (ANOVA) test were used to give statistical results and to form a profile analysis. Analysed results show that treatment with Sutherlandia frutescens 200CH significantly improves several common signs and symptoms experienced by HIV positive people, including oral candidiasis, fever and skin rashes; a number of other pathologies showed improvement, but not to a statistically significant level. The analysis of CD4 cell counts demonstrated a significant decrease of absolute CD4 cell counts during the course of the study, even in the presence of a stable CD4 percentage. Statistical analysis also indicated a lack of consistency in change of CD4 percentage and absolute CD4 between participants, as well as a lack of correlation between change of CD4 percentage and absolute CD4 changes. As NO was not tested directly no assumption can be made as to how these results might have been influenced. Further research into the use of Sutherlandia frutescens in the treatment of HIV is none the less to be recommended given its reported large number of medicinal properties and its extensive use as an herbal supplement in HIV treatment in South Africa.
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Hächler, Geraldine Chantal. "The efficacy of the homoeopathic similimum in the treatment of irritable bowel syndrome in women." Thesis, 2012. http://hdl.handle.net/10210/7548.
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M.Tech.Irritable bowel syndrome (IBS) is a multifactoral disorder of the gastrointestinal tract causing disturbances in gastric motility, resulting in abdominal pain, bloating and abnormal bowel movements. It is defined as a 'disorder of gut function in the absence of structural pathology' (Palmer et a!, 2002). It is the most commonly encountered functional gastrointestinal disorder in the primary and secondary health care system with a prevalence in the general population of five to twenty percent (Bellini et a!, 2005). No definite aetiological factor has been isolated, but factors such as psychological stress, anxiety and depression, certain dietary intolerances, increase in abnormal sensitivity to visceral distension, and hormonal changes in women have been implicated in compounding the symptoms of IBS (Ohman & Simren, 2007). Current treatment regimes include dietary changes and symptomatic relief using allopathic medications, which come with the risk of side-effects and may lead to dependency (University of Maryland Medical Center, 2007). Homoeopathic studies which have addressed the physical symptoms as well as the psychological contributing factors associated with IBS, have recorded favourable results when treating this syndrome (Mathie & Robinson, 2006).The aim of this research was to determine the efficacy of Homoeopathic Similimum treatment in IBS. In order to recruit volunteers, this study was advertised in local newspapers, pharmacies and at the University of Johannesburg's Doornfontein Campus. Volunteers completed the Rome III Criteria evaluation to determine their suitability for this study, with the likelihood of any other bowel pathology having been excluded. Ten suitable female volunteers, ranging in age from twenty to thirty five, were selected having met the inclusion criteria. Over a period of three months, each participant partook in four homoeopathic consultations. The initial consultation involved the completion of the information and consent form, an explanation of the research procedures, general well-being and general symptom rating questionnaires were completed, a full homoeopathic case history was taken, and a physical examination was performed. A baseline of four weeks without treatment followed. Participants were requested to complete daily symptom rating scales and keep a daily food diary in the four weeks between consultations. This was continued throughout the study period. The subsequent follow-ups, of which there were three, consisted of a follow-up on the initial consultation, completion of general well-being and symptom rating questionnaire, and a physical examination. A homoeopathic similimum remedy was chosen based on each participant's unique symptoms. Using physical, mental, and emotional symptoms in accordance with classical homoeopathic principles, a single remedy that most suited the individual was chosen and prescribed. It was predicted that the study would provide an alternative and safe treatment option to relieve the symptoms ofiBS. The results of the study showed that the homoeopathic similimum remedy does not provide a statistically significant improvement in the symptoms of IBS. Clinically, however, most participants experienced a general trend of improvement in physical symptoms and general well-being .
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Swan, Carla. "The efficacy of homoeopathic simillimum versus vitamin C (1000mg) in the treatment of influenza type syndrome." Thesis, 2003. http://hdl.handle.net/10321/2696.
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Dissertation submitted in partial compliance with the requirements for the Masters Degree in Technology: Homoeopathy at Durban Institute of Technology, 2003.The purpose of this double blind randomised study is to evaluate the efficacy of homoeopathic simillimum versus high doses of vitamin C in the treatment of Influenza Type Syndrome in terms of subjective symptoms assessed by the patient, and objective clinical signs assessed by the researcher
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Pieterse, Catherina Petronella. "A comparative study of the homoeopathic complex remedy Spascupreel and the homoeopathic simplex remedy Zincum metallicum in a D6 potency in the treatment of Restless Leg Syndrome." Thesis, 2014. http://hdl.handle.net/10210/9010.
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M.Dip.Tech. (Homoeopathy)The aim of the study was to compare the effectiveness of the Homoeopathic simplex Zincum metallicum in a D6 potency with the Homoeopathic complex treatment Spascupreel in Restless leg syndrome sufferers in terms ofpatient response to treatment. It was hypothesised that the Homoeopathic simplex Zincum metallicum in a D6 potency.Both the homoeopathic simplex Zincum metallicum D6 preparation and homoeopathic complex Spascupreel preparation was found to bring about an improvement in the symptoms ofrestless leg syndrome. However Zincum metallicum D6 showed a much greater improvement that was statistically significant. and the Homoeopathic complex Spascupreel would result in a substantial improvement in all the clinical aspects ofRestless leg syndrome sufferers, and that it could be used as an alternative to "conventional" treatment in many cases. The study, conducted over a period of 3 months, was a clinical trial, in which a placebo control group was compared with two experimental groups. Convenience sampling was used to draw patients into the trial. Volunteers responded to advertisements, which had been placed in various advertising media. The persons who responded to the advertisements were requested to complete Questionnaires one and two and of those who met the criteria, which clearly indicated that they were sufferers of Restless leg syndrome, a maximum of 30 volunteers were accepted for the study. An independent party randomly divided the participants into three groups and the study was conducted over a period ofthree months. During this period 10 of the participants received placebo treatment, 10 received the Homoeopathic simplex Zincum metallicum in a D6 potency and 10 received the Homoeopathic complex Spascupreel. Being a double-blind study neither the researcher nor the participants knew what type of treatment they received until the end of the research. The participants who fell into the placebo group were given the opportunity after the study to be treated with Homoeopathic simplex or complex treatment depending on the effectiveness.
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Schultz, Jacquelyn Loren. "A study to determine the effectiveness of the homoeopathic remedies Argentum nitricum 6CH and Lycopodium clavatum 6CH on the individualised treatment of patients suffering from irritable bowel syndrome." Thesis, 2014. http://hdl.handle.net/10210/10589.
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M.Tech. (Homoeopathy)The aim of this study was to determine the effectiveness of Argentum nitricum 6CH and Lycopodium clavatum 6CH in the individualised treatment of patients suffering from Irritable bowel syndrome. These two homoeopathic remedies are well known for their effect on the gastrointestinal system, especially when the gastrointestinal symptoms are associated with emotional stress. 60 subjects participated in this single blind, placebo controlled study. Each subject underwent an initial evaluation in order to ascertain their symptoms prior to treatment. They were then given their appropriate remedy to be administered three times daily for one month. The subject's symptoms were monitored through questionnaires completed at two week intervals. The homoeopathic medication appeared to reduce the Irritable bowel syndrome symptoms, with the Lycopodium clavatum group achieving slightly better results than the Argentum nitricum group. It is, however, recommended that further similar studies using a larger sample group for a longer duration be conducted in order to verify these findings.
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Lötter, Ingrid. "The efficacy of the homeopathic remedy Discus Compositum® in the treatment of lumbar facet syndrome." Thesis, 2010. http://hdl.handle.net/10210/3160.
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M. Tech.Low back pain is experienced by approximately 60-90% of the population and is one of the most expensive public health problems today (Shin and Slipman, 2005). Lumbar facet joint syndrome is a common condition, involving about 79% of patients suffering from low back pain (Schleifer, et al., 1994). The aim of this study was to determine the effectiveness of treatment for lumbar facet syndrome with the homeopathic injectable Discus compositum® by using the pressure algometer, Helbig and Lee scorecard system and the Oswestry low back pain questionnaire. This double-blind placebo-control trial, with matched pairs, was conducted at the University of Johannesburg and participants were recruited with posters and by word of mouth. Thirty-two participants that met the inclusion criteria, and were not outside of treatment parameters, were included in the study. These participants were then randomly divided into two groups: Group A was treated with Discus compositum® injectables and Group B was treated with placebo injectables. In addition, participants were matched according to activity levels of more than 3 times per week and activity levels of less than 3 times per week. Participants in both groups were treated four times over a period of two weeks; two treatments per week. A one month post-injection follow-up consultation was carried out in order to determine if the treatment had a lasting effect. The subjective and objective data was analysed by using non-parametric tests in order to establish statistical significance between visits and between groups. The subjective data was obtained by using the Oswestry low back pain and disability questionnaire. The objective data was gathered by using the Helbig and Lee scorecard system as well as the algometer readings. The two sample groups did exhibit statistical differences. The results showed that there was a significant decrease in the pain experienced by the participants, as well as a significant change in the participant’s pain pressure threshold, for both groups. With regards to the diagnostic criteria a higher percentage of participants that were treated with Discus compositum® injections were no longer diagnosed with lumbar facet syndrome according to the Helbig and Lee scorecard system, than those participants that were treated with the placebo injections. In addition, it was determined that a combination of Discus compositum® injections and activity levels of more than 3 times per week proved to be beneficial. Based on the results of this study, one can determine that Discus compositum® is effective in the treatment of lumbar facet syndrome.
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Du, Toit Chrisna. "The efficacy of Ruta graveolens 6cH in the treatment of computer vision syndrome." Thesis, 2012. http://hdl.handle.net/10210/4759.
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M. Tech.The homoeopathic remedy, Ruta graveolens, is used for the treatment of eyestrain and eye related symptoms caused by the over use of the eyes (Kent, 2006). The aim of this study was to determine the efficacy of the homoeopathic remedy Ruta graveolens 6cH in the treatment of Computer Vision Syndrome. This study can be compared to related studies by means of the symptom index form (Appendix C). This double-blind study included thirty participants between the ages of 20 and 35. The participants had to be regular users of a visual display terminal for a minimum of three hours per day. The participants also had to experience at least two or more eye or vision related symptoms due to VDT use for at least one month prior to the start of the study. During the first consultation, each participant was tested for any refractive errors by a qualified optometrist. The participants were divided into two groups of fifteen each. One group received the remedy, Ruta graveolens 6cH, while the other group received the placebo. The participants were required to take four pillules twice a day for the duration of the study. The data was statistically analysed by means of the Mann-Whitney u Test, Friedman Analysis of Variance by Ranks Test and Wilcoxon Signed-Rank Test. Crosstabs were used to check for confounding variables. The two groups, the placebo and the treatment group were tested against each other. The findings from the data illustrated that in the treatment group there was a statistically significant improvement in the severity of symptoms in seven of the fourteen symptoms over the duration of the study, while five of the fourteen symptoms of the placebo group had a statistically significant improvement in severity over the four week period. Overall the severity of the treatment group had an improvement of 42% compared to the 28% improvement of the placebo group. Both groups showed a reduction of the frequency of symptoms over the duration of the study.
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Hassim, Zeenat. "The efficacy of Ruta graveolens 6CH together with ergonomic interventions in the work-place in the treatment of computer vision syndrome." Thesis, 2012. http://hdl.handle.net/10210/4753.
Full textAbstract:
M.Tech.As computers become more common in the work environment, more people are developing symptoms linked to long-term computer use. These include visual and eye-related symptoms as well as musculo-skeletal symptoms (Sheedy & Shaw-McMinn, 2003; Yan, Hu, Chen & Lu, 2007). This collection of symptoms is known as Computer Vision Syndrome (CVS). There are various allopathic modes of treatment available which are limited in terms of their long term use and side effects. Yan and colleagues (2007) indicate that a correctly designed, ergonomically efficient work place plays a significant role in limiting the development of CVS symptoms. Depending on the reasons for CVS and the symptoms associated with it, alternative treatment options may be appropriate (Yan, et al., 2007). Homoeopathy offers alternate treatment, however no extensive research has been done on the homoeopathic treatment of this condition. The aim of this study was to determine the efficacy of the homoeopathic remedy Ruta graveolens 6cH together with ergonomic interventions in the work environment in the treatment of Computer Vision Syndrome. This was done by means of a selection questionnaire (APPENDIX B) and a symptom index form (APPENDIX C), rating the severity and frequency of symptoms. This research study is paired to a related study which investigated the efficacy of Ruta graveolens 6cH without ergonomic interventions. These two studies can later be compared to determine whether the remedy Ruta graveolens 6cH by itself is sufficient in treating computer vision syndrome. This study was approved by the Higher Degrees Committee (HDC48/2009) and the Academic Ethics Committee (AEC50/09) at the University of Johannesburg on the 19 June 2009. Thirty one people joined the study. They were recruited by means of flyers and advertisements (APPENDIX E) placed at the University of Johannesburg as well as corporate companies. Participation was voluntary and by means of informed consent (APPENDIX A). Participants were required to fill in a selection questionnaire (APPENDIX B) to see if they qualified for the study. It was a double-blind placebo controlled study in which participants were placed into one of 2 groups. Both groups were required to change the layout of their work environment in order to ensure ergonomic efficiency at their work station (APPENDIX D). Of the two groups, one was dispensed vi the medicated prescription and the other an identically presented unmedicated prescription. Participants were requested to take the medication twice a day for 4 weeks. They were also required to complete a symptom index form (APPENDIX C) on a weekly basis. These forms were collected by the researcher at the end of the four weeks. There was no risk associated with taking the medication. Participants’ right to privacy was adhered to and they were free to withdraw from the study at any time. Of the 31 people who joined the study, 29 completed the study.