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Journal articles on the topic 'Hormonal imbalance'
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Hugara, Sharvani, Sumanji Bala, and Jayashree B Gaja. "A Short Survey for Understanding Hormonal Imbalance and Its Causes." International Journal of Research and Review 11, no. 4 (2024): 412–17. http://dx.doi.org/10.52403/ijrr.20240445.
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Women's health is greatly affected by hormones. Women's hormonal imbalances can be brought on by a variety of as an assortment of variables, including stress, medical condition, use of drugs, tension, lifestyle changes, etc. increased use of pesticides, and many other chemical substances, environmental pollute affects the overall health of the people. The understanding of causes of hormonal variations is most important for female wellbeing. A specially designed data sheet was used for the collection and analysis for causes of hormonal imbalance in urban area Bangalore females. Our overview investigates contributing variables hormonal lopsided characteristics in females. However Hormonal imbalance affects several ways in women. Sometimes medication may lead to interference in hormone levels. The present study deals with some of the symptoms and signs correlated with hormone imbalance that if unrecognized may lead to shortening of life time. It is most be all for to take the advice of health practitioner to upgrade he lifestyle and dietary habits. Hormones play a vital role in the health of human females and hormonal imbalance can cause several pathological conditions. Improper diet, stressful or depressed lifestyles and use of drugs can cause hormonal imbalance. This study aimed for consider pointed to discover out the causes of hormonal imbalance in females aged between 15-50 years. A cross-sectional and random sampling method was used to collect data from young females of this age group in Bangalore, A specially designed questionnaire was used for data collection and a total of 240 females participated in the study. Keywords: HORMONAL IMBALANCE, STRESS, DIET, AGE, PCOS
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Arsovska, Blagica, Jihe Zhu, and Kristina Kozovska. "CASE REPORT - ACUPUNCTURE TREATMENT IN PATIENT WITH HORMONAL IMBALANCE." International Journal of Research -GRANTHAALAYAH 9, no. 6 (2021): 307–10. http://dx.doi.org/10.29121/granthaalayah.v9.i6.2021.4046.
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Hormones play a big role and are a huge part of women’s health, including physically, mentally and emotionally. If the body produces too little or too much of some certain hormones, then the hormonal imbalance occurs. According to TCM, two organs mainly connected to the hormonal imbalances are the Kidney and the Liver. The aim of the TCM treatment for hormonal imbalance is to balance the Yin and Yang energy in the organs and the body and restore the . In this research is presented a case of a woman presented with reduced function of the thyroid gland and hormonal imbalance. Before starting the treatment the results are showing increased levels of TSH (8.08 /ml), LH (12.30 /ml) and FSH (15.70 /ml) and decreased levels of fT4 (9.78 /L). After the treatment the TSH (2.79 /ml), fT4 (14.00 /L) and LH (7.93 /ml) were normalized and FSH (12.20 /ml) was decreased with only 7 treatments within 7 weeks. Acupuncture points used in the treatment are: DU4 (MingMen), DU14 (DaZhui), DU20 (BaiHui), RN6 (QiHai), RN4 (QuanYuan), BL15 (XinShu), BL20 (PiShu), GB20 (FengChi), ST9 (RenYing), LI4 (HeGu), BL23 (ShenShu), LR2 (TaiChong), SP6 (SanYinJiao), ST36 (ZuSanLi), SP9 (YinLingQuan), KI3 (TaiXi) and points located on the neck (front and back). Acupuncture as part of the TCM can effectively help the patients struggling with hormonal imbalances to balance and regulate the hormones and harmonize the metabolism, nervous, reproductive and endocrine system.
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Semeniuk, L. N. "Possibilities of non-hormonal correction of menstrual disorders in women of reproductive age." HEALTH OF WOMAN, no. 9(135) (November 30, 2018): 107–10. http://dx.doi.org/10.15574/hw.2018.135.107.
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tissues of the Ministry of Health of Ukraine, Kiev The article presents new data on the prevention of reproductive disorders in women with functional hormonal imbalances. Disruption of the menstrual cycle is considered to be the combined result of hormonal dysfunction and the negative influence of the environment during chronic stress. The role of non-hormonal therapy in improving the quality of life and eliminating hormonal imbalance in women of reproductive age is shown. Key words: female reproductive function, hormonal imbalance, proliferation.
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Saul, Sugantha. "Effects of vitex agnes castus on hormonal imbalances in Polycystic Ovary Syndrome." International Journal of Basic & Clinical Pharmacology 6, no. 8 (2017): 2051. http://dx.doi.org/10.18203/2319-2003.ijbcp20173295.
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Background: The polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in women. Its incidence is assessed at 6-8% of the female population in the reproductive age. It is caused by an imbalance of the female sex hormones and higher levels of male hormones called androgens.Methods: In women with PCOS, the ovaries make more androgens than normal. High levels of these hormones affect the development and release of eggs during ovulation. Hence the hormonal imbalance were studied in three groups. In the present study ,8mg of estradiol valerate was used to induce PCOS in female albino rats. The levels of leutinizing hormone, follicle stimulating hormone, testosterone, dehydroepiandrosterone sulphate, Estradiol, Progesterone, and Prolaction were studied.Results: The phytochemical analysis of vitex agnus castus was carried out and the positive effects of vitex agnus castus on the hormonal irregularities of PCOS were also studied. The present findings indicated that vitex agnus castus was found to be rich in phytochemicals.Conclusions: The hormonal levels highly reflect the underlying hormonal imbalance in PCOS and the results obtained in the present study also proved that vitex agnus castus is more efficient in reversing the adverse effects of hormonal imbalance of PCOS.
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Suresh, K. "The Need and Management of hormone Imbalances in Women." Endocrinology and Disorders 8, no. 1 (2024): 01–10. http://dx.doi.org/10.31579/2640-1045/163.
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Hormones in human body have mythical qualities to some people. Most of us, as we age would say- If I just had my hormones back the way they were, it would all work out better’! Hormonal imbalances are more common in women around puberty, menstruation, pregnancy, menopause, and even years after Menopause (Post-menopause) aging. Some women experience continual, irregular hormonal imbalances leading to a variety of health issues, including mental health disturbances like depression or Anxiety. The symptoms of hormonal imbalance in women are heavy or irregular periods, hair loss, night sweats, headaches, and psychosocial disturbances to the individual & family. Most individuals think that Oestrogen and Testosterone are exclusively female and male hormones respectively. The reality is both are present and required in both sexes. The main reproductive hormones testosterone, oestrogen, and progesterone are instrumental for sexuality and fertility. They are responsible for puberty, menstruation, pregnancy, menopause, sex drive, ovum production and more. Preserving individual’s hormone levels within normal ranges helps every single woman to retain youthful feelings. While managing hormonal imbalance with natural remedies, like- regular physical exercises, maintaining age-appropriate weight, reducing getting stressed or anxious, avoiding sugars, and having adequate sleep is better, it may not be possible for all and always. For individuals who can’t balance hormones naturally consulting a doctor for a hormone therapy (HT) would be the best option. The hormones usually used are oestrogen and progesterone, to replace those that the body has stopped making or doesn't make enough or to negate the effect if what is produced is higher than required. It is current day need and urgency for the primary care /Family physicians to ensure that patients with hormonal imbalance are heard, their symptoms recognized and ascribed to the appropriate problems and referred and followed-up or managed. This article is meant to provide the evidence of when and when not to prescribe Oestrogen. Materials and Methods: The author has used cases from his personal practice over 5 decades and close specialist friends who guided hormone therapy. A thorough literature research both national a d global practices are to put together to the evidence of when and when not to prescribe hormones for women.
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Kishanrao, Suresh. "If women just had their hormones back the way they were! (for youthful feeling-balance your hormones!)." Clinical Endocrinology and Metabolism 2, no. 4 (2023): 01–11. https://doi.org/10.31579/2834-8761/025.
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"Hormones in human body have mythical qualities to some people. Most of us, as we age would say- 'If I just had my hormones back the way they were, it would all work out better’! Hormonal imbalances are more common around puberty, menstruation, pregnancy, menopause, and aging, but some people experience continual, irregular hormonal imbalances leading to a variety of health issues. The symptoms of hormonal imbalance in women are heavy or irregular periods, hair loss, night sweats, headaches, and psychosocial disturbances to the individual & family. General population think that Oestrogen and Testosterone are exclusively female and male hormones respectively. The reality is both are present and required in both sexes. The main reproductive hormones oestrogen, testosterone, and progesterone are instrumental for sexuality and fertility. They are responsible for puberty, menstruation, pregnancy, menopause, sex drive, ovum production and more. Balancing or preserving our hormone levels within normal ranges helps us retain youthful feelings. While managing hormonal imbalance with natural remedies, like- regular physical exercises, maintaining age-appropriate weight, reducing getting stressed or anxious, avoiding sugars, and having adequate sleep is better, it may not be possible for all and always. For individuals who can’t balance hormones naturally consulting a doctor for a hormone therapy (HT) would be the best option. The hormones usually used are oestrogen and progesterone, to replace those that the body has stopped making or doesn't make enough or to negate the effect if what is produced is higher than required. It is current day need and urgency for the primary care /Family physicians to ensure that patients with hormonal imbalance are heard, their symptoms recognized and ascribed to the appropriate problems and referred and followed-up or managed. This article is meant to provide the evidence of when and when not to prescribe Oestrogen. Materials and Methods: The author has used cases from his personal practice over 5 decades and close specialist friends who guided hormone therapy. A thorough literature research both national a d global practices are to put together to the evidence of when and when not to prescribe hormones for women.
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Ekong, Victor. "SOFT COMPUTING SYSTEM FOR THE DIAGNOSIS OF HORMONAL IMBALANCE." Transactions on Machine Learning and Artificial Intelligence 7, no. 6 (2020): 30–42. http://dx.doi.org/10.14738/tmlai.76.7507.
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Soft computing, as a science of modelling systems, applies techniques such as evolutionary computing, fuzzy logic, and their hybrids to solve real life problems. Soft computing techniques are quite tolerant to incomplete, imprecise, and uncertainty when dealing with complex situations. This study adopts a hybrid of genetic algorithm and fuzzy logic in diagnosing hormonal imbalance. Hormones are chemical messengers that are vital for growth, reproduction, and are essential for human existence. Hormones may sometimes not be balanced which is a medical condition that often go unnoticed and it’s quite difficult to be diagnosed by medical experts. Hormonal imbalance has several symptoms that could also be confused for other ailments. This proposed system serves as support for medical experts to improve the precision of diagnosis of hormonal imbalance. The study further demonstrates the effective hybridization of genetic algorithm and fuzzy logic in resolving human problems.
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Gauri Sandip Thakare, Neha Laxmanrao Zod, and Harigopal Shalimar Sawarkar. "Breast cancer: A comprehensive review and it’s side effect." World Journal of Biology Pharmacy and Health Sciences 20, no. 2 (2024): 499–513. http://dx.doi.org/10.30574/wjbphs.2024.20.2.0900.
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People worldwide are impacted by breast cancer, which is a complex, multidimensional illness. The importance of understanding the intricate relationships between hormones and breast tissue is highlighted by the discovery that hormonal imbalance has been connected to the development of breast cancer. The many forms and phases of breast cancer have been clarified by the review. This comprehensive investigation looks at the involvement of key hormones, including progesterone and estrogen, and their receptors in tumor growth in an effort to clarify the significance of hormonal imbalance in breast cancer. The review looks at the effects of hormonal imbalance on breast tissue, with a focus on how hormone receptor status affects treatment choices. The importance of hormone testing in making decisions about diagnosis and therapy, as well as the consequences of hormonal imbalance evaluation in the risk assessment of breast cancer are also covered. An important but little-known side effect of cancer is oral mucositis, which is also covered in the study. The expression "oral mucositis" describes erythematous and ulcerative lesions of the oral mucosa that occur in cancer patients' oral cavities as a result of chemotherapy or radiation therapy. One study concluded that GI or oral mucositis developed in 303 out of 599 patients (51%) undergoing chemotherapy for solid tumors or lymphoma. This study illustrates the way a thorough knowledge of hormonal imbalance is necessary to improve breast cancer detection, treatment, and prevention strategies. The pathogenesis, clinical treatment, and risk factors of oral mucositis are also examined in this article, which will ultimately benefit those who are afflicted.
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Glushkov, Andrew N. "Immune-hormonal imbalance in chemical cancerogenesis." Russian Journal of Immunology 25, no. 1 (2022): 23–36. http://dx.doi.org/10.46235/1028-7221-1091-ihi.
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The present article deals with experimental and clinical aspects of immuno-hormonal interactions in chemical carcinogenesis i.e., formation of DNA-adducts with chemical carcinogens as a trigger of tumor initiation; synthesis of specific antibodies as markers of human exposure to environmental carcinogens; immunomodulation of chemical carcinogenesis by the specific antibodies in experimental studies; interactions of antibodies against environmental carcinogens with endogenous steroid hormones in human carcinogenesis; immunological interference and inversion of immuno-hormonal interactions by the action of antibodies against environmental carcinogens; immune stimulation of tumor progression in cancer patients. It is shown that antibodies specific to estradiol and progesterone participate in regulation of serum estradiol and progesterone levels in healthy women. Excessive production of antibodies against benzo[a]pyrene is associated with impaired physiological balance between the levels of antibodies to estradiol and progesterone, thus causing disturbed physiological balance between serum estradiol and progesterone. Immuno-hormonal imbalance promotes tumor initiation, its growth and progression. The new approaches to the personalized cancer immunoprediction and immune prevention are discussed. Coordinated synthesis of antibodies against benzo[a]pyrene and estradiol seems to reflect production of DNA-adducts with genotoxic metabolic effects of these compounds manifesting as synergistic carcinogenic effects upon the target cells. Hence, simultaneously increased levels of serum antibodies against benzo[a]pyrene and estradiol in healthy people may be considered an immunological marker of high oncological risk and an reason to use of new immunoprotective tools against polycyclic aromatic hydrocarbons and phytoestrogens. However, ability of these antibodies to raise the blood serum levels of environmental carcinogens and endogenous estradiol, as shown in vitro and in vivo, excludes the opportunity for active cancer immune prevention. Usage of anticarcinogen vaccines aimed for induction of protective secretory antibodies is likely to further increase high levels of procarcinogenic serum antibodies against benzo[a]pyrene and estradiol, followed by additional enhancement of immuno-hormonal imbalance and promotion of carcinogenesis. Development of probiotics transduced with genes encoding human antibodies against environmental carcinogens may present an alternative approach to cancer immune prevention. The antibodies produced by such probiotics would bind appropriate carcinogens and prevent their invasion into the organism, thus inhibiting emergence of DNA-adducts and suppressing synthesis of specific autoantibodies that may promote carcinogenesis. The aim is to substantiate the concept of immuno-hormonal imbalance for the carcinogen-induced hormone-dependent tumors.
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Roman, Alexandra-Maria, Răzvan-Cosmin Petca, Mihai Cristian Dumitrașcu, Aida Petca, Andreea-Iuliana Ionescu (Miron), and Florica Șandru. "Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in Disease Development." Journal of Personalized Medicine 14, no. 1 (2024): 72. http://dx.doi.org/10.3390/jpm14010072.
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Frontal Fibrosing Alopecia (FFA) is a distinctive form of cicatricial alopecia characterized by gradual hairline recession, predominantly affecting postmenopausal individuals, thus implying a potential hormonal origin. This narrative review, spanning 2000 to 2023, delves into PubMed literature, focusing on the menopausal and hormonal status of women with FFA. The objective is to unravel the intricate nature of FFA and its plausible associations with hormonal dysregulations in women. While menopause remains a pivotal demographic characteristic linked to FFA, existing data suggest that its hormonal imbalances may not fully account for the development of FFA. Conversely, substantial evidence indicates a strong association between a reduction in fertile years, particularly through surgical interventions leading to an abrupt hormonal imbalance, and FFA in women. Additionally, exposure to hormone replacement therapy or oral contraceptives has shown varying degrees of association with FFA. Gynecologists should maintain a heightened awareness regarding the ramifications of their interventions and their pivotal role in overseeing women’s fertility, recognizing the potential influence on the progression of FFA. The recurrent theme of hormonal disruption strongly implies a causal connection between alterations in sex hormones and FFA in women. Nevertheless, this relationship’s extent and underlying mechanisms remain subjects of ongoing debate.
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Ch, Renuka Devi, and Jhansi Rani N. "Impact of Yoga therapy on hormonal imbalance in women with Polycystic Ovarian Disease." International Journal of Ayurvedic Medicine 14, no. 1 (2023): 206–12. http://dx.doi.org/10.47552/ijam.v14i1.3357.
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The current study aims to evaluate the impact of yoga therapy on hormonal imbalance in PCOS affected women. An empirical study was conducted on 25 women having been diagnosed with PCOS condition. The study used pre and post design. Before starting allopathic medication participants were explained about yoga therapy and participants in the study voluntarily agreed to participate in this study without using medication. Written consent was obtained from the participants. Testosterone, Prolactin, Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), were selected as dependent variables for this study. Before introducing the yoga therapy intervention, baseline hormonal values were collected through blood tests. All the 25 participants practiced yoga protocol specially designed for PCOS condition, for a duration of 12 weeks. At the end of 12 weeks the participant took the blood test in the laboratory for hormonal levels of PCOS related hormones selected for this study. Baseline data was compared with Post data. The impact of yoga therapy on the hormonal imbalance was statistically analysed through paired t-test. The statistical analysis yielded following t values: Serum Testosterone 21.52 (P <0.001), Serum Prolactin 22.13 (P<0.001), Serum LH 30.10 (P<0.001), and Serum FSH 14.16 (P<0.001). The impact of yoga therapy intervention on hormones related to PCOS condition was found to be significantly positive. The results imply that regular yoga practice can be an effective therapy for women with PCOS, especially for correcting imbalance in hormone levels related to PCOS.
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Samuseva, N. L., N. M. Kurch, and V. E. Vysokogorskiy. "Hormonal imbalance in prenatally alcoholized rat offspring." Kazan medical journal 94, no. 5 (2013): 740–43. http://dx.doi.org/10.17816/kmj1933.
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Aim. To identify the role of hormonal imbalance in the development of hypoglycemia in rats exposed to prenatal alcohol intoxication. Methods. Effects of prenatal alcohol intoxication on carbohydrate metabolism regulation in rat youngs aged 15, 30 and 60 days were studied. For this purpose, intragastral injections of 40% ethanol (4 g/kg) were performed in female white random rats during the gestation period. Glucose, insulin, glucagon, cortisol, thyroid hormones serum concentrations were determined. Results. In offspring of rats exposed to alcohol during the prenatal period, increased blood insulin concentration at the age of 30, 60 days, reduced glucagon concentration at the age of 60 days were found. These changes were accompanied by persistent hypoglycemia. Plasma cortisol concentration in rats exposed to alcohol during the prenatal period had no any statistically significant differences compared to a control group. Statistically significant reduction of triiodothyronine in the age of 60 days accompanied by an increased blood thyroxin level was also observed. Conclusion. The gained results suggest the essential influence of prenatal alcohol intoxication on carbohydrate metabolism regulation in the remote terms of postnatal period. Prenatal alcohol exposure leads to the development of differently directed changes in offspring blood insulin, glucagon and thyroid hormones remaining in remote periods of postnatal ontogenesis, that may play a significant role in the development of hypoglycemia, and define the high level of the still birth and early postnatal mortality.
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Oliveira, Katia C., Rita Cardoso, Antonio C. Dos Santos, Ruben Fernandes, and Monica C. Botelho. "Imbalance of Steroid Hormones in Hamsters Infected with Schistosoma mansoni." Endocrine, Metabolic & Immune Disorders - Drug Targets 19, no. 8 (2019): 1122–26. http://dx.doi.org/10.2174/1871530319666190529121204.
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Objective: Schistosomiasis is a debilitating disease that affects 200 million people worldwide. Schistosoma haematobium and Schistosoma mansoni are the major causative agents of this disease. Cancer-association and infertility-association in Schistosoma haematobium infection have already been described and it is known that the parasite produces a catechol-estrogen molecule that induces a hormonal imbalance in the host. Methods: In order to better understand the relation of hormonal imbalance in experimental Schistosoma mansoni infection, we investigated a serum panel of steroid hormones in Schistosoma mansoni infected hamsters. Results: We found a decrease in the serum levels of Estradiol (E2), Testosterone and Progesterone in infected females and an increase of Testosterone and a decrease in Progesterone in infected males in comparison with controls. Conclusion: These results indicate that S. mansoni alters the levels of steroid hormones in infected males and females and it will increase the repertoire of data about the host-parasite molecular interplay and its relation with the endocrine system.
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Kamarova, Ibodat Nuriddinovna, and Zarina Dilmurod qizi Norbo`tayeva. "The Influence of Hormonal Imbalances on Female Reproductive Health." Multidisciplinary Journal of Science and Technology 5, no. 2 (2025): 360–61. https://doi.org/10.5281/zenodo.14871320.
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Hormonal balance is essential for female reproductive health, regulating ovulation, menstruation, pregnancy, and overall endocrine function. Disruptions in hormonal levels, including estrogen, progesterone, androgens, and thyroid hormones, can lead to conditions such as polycystic ovary syndrome (PCOS), endometriosis, amenorrhea, and infertility. This article explores the causes and effects of hormonal imbalances, their impact on the female reproductive system, and current treatment approaches, including hormonal therapy, lifestyle modifications, and emerging pharmacological treatments.
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Ali, A. Al-Fahham, and Q. Al-Nowainy Hisham. "The role of FSH, LH, and Prolactin Hormones in Female Infertility." American Journal of PharmTech Research 6, no. 5 (2023): 110–18. https://doi.org/10.5281/zenodo.8197537.
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ABSTRACT Recently, a great attention has been paid to the role of hormones as a diagnostic too in the evaluation of female infertility . The purpose of this study was to identify the association between female infertility and hormonal imbalance (FSH, LH and Prolactin) and what is the relationship between these hormones and the woman's socio- demographic and clinical characteristics. The study was carried out at the Fertility Center in Al-Sadr Medical City, which is located in Najaf province, Iraq, during the period from Dec, 2014 to Apr, 2015. The study involved (44) infertile women who attended the Fertility Center. In accordance to the socio-demographic data, the majority of the studies women were from urban regions (81.18%), while all them were housewives. The clinical history revealed a relatively high percentage (56.82%) of vaginitis, and UTI (50%) among the studies women, while most of them were either overweight (40.91%) or obese (22.73%). The results showed that the majority of studies women had normal hormonal levels according to the standard reference limits for FSH, LH and Prolactin. The study also showed that there was a significant positive correlation between the level of FSH and the age of the studies infertile women. It was concluded that hormonal imbalance for (LH, FSH and prolactin) is just a minor suspected etiologic factor in causing infertility in the studies women the level of FSH increases with age, while the level of prolactin slightly decreases with age. It was recommended to achieve a comprehensive case-control study for evaluating hormonal imbalance of (FSH, LH, prolactin, estrogens, progesterone, thyroid and inhibit) hormones in the infertile women
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P, Nivedha, and Ramya N. "Impact of Unbalanced Diet Causing Hormone Imbalance in the Middle-Aged Women." International Journal of Agro Nutrifood Practices 1, no. 1 (2021): 11–14. http://dx.doi.org/10.36647/ijanp/01.01.a003.
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Hormones perform a crucial role in women's health. Variations in hormone levels (estrogen and progesterone) can negatively affect women's mood, sexual desire, ovulation process, and fertility. A balanced and healthy diet has a major influence on various hormonal processes and facets of our wellbeing. There are multiple factors related to diets, such as food sensitivity leading to allergic reactions, obesity, inflammation from inadequate diet and sedentary lifestyles, sleep habits, digestion, and others. All these factors contribute to hormonal imbalances and associated complications. Diet-derived circulating constituents can perform immediate and indirect actions for receptor activation, signalling, and supplying micronutrients.
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Abramicheva, Polina A., and Egor Y. Plotnikov. "Hormonal Regulation of Renal Fibrosis." Life 12, no. 5 (2022): 737. http://dx.doi.org/10.3390/life12050737.
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Fibrosis is a severe complication of many acute and chronic kidney pathologies. According to current concepts, an imbalance in the synthesis and degradation of the extracellular matrix by fibroblasts is considered the key cause of the induction and progression of fibrosis. Nevertheless, inflammation associated with the damage of tissue cells is among the factors promoting this pathological process. Most of the mechanisms accompanying fibrosis development are controlled by various hormones, which makes humoral regulation an attractive target for therapeutic intervention. In this vein, it is particularly interesting that the kidney is the source of many hormones, while other hormones regulate renal functions. The normal kidney physiology and pathogenesis of many kidney diseases are sex-dependent and thus modulated by sex hormones. Therefore, when choosing therapy, it is necessary to focus on the sex-associated characteristics of kidney functioning. In this review, we considered renal fibrosis from the point of view of vasoactive and reproductive hormone imbalance. The hormonal therapy possibilities for the treatment or prevention of kidney fibrosis are also discussed.
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Tanwar, Suman, Bhawna Mattoo, Uma Kumar, Nandita Gupta, and Renu Bhatia. "IS FIBROMYALGIA A SYNDROME OF HORMONAL IMBALANCE?" Asian Journal of Pharmaceutical and Clinical Research 11, no. 7 (2018): 416. http://dx.doi.org/10.22159/ajpcr.2018.v11i7.24016.
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Objectives: The present study was conducted to estimate cortisol and thyroid-stimulating hormone (TSH) levels in patients with fibromyalgia syndrome (FMS) and to find correlation if any between hormone levels and pain duration in FMS.Methods: Plasma cortisol and TSH concentration were determined by electro chemiluminescence immunoassay in 89 female patients with FMS and 74 age-matched healthy women.Results: No significant difference in TSH level was observed between FMS and healthy subjects. Ten patients had higher cortisol levels than the standard reference range, 48 patients with reduced cortisol and 31 patients with normal cortisol levels. No significant correlation was observed between pain duration and levels of cortisol.Conclusion: The study has confirmed the equivocal data regarding cortisol/hypothalamic-pituitary-adrenal axis related dysfunction in FMS. To the best of our knowledge, it is the first Indian study on FMS which assessed the cortisol and TSH levels and their correlation with pain duration if any.
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Adaikan, P. G., and B. Srilatha. "Oestrogen-mediated hormonal imbalance precipitates erectile dysfunction." International Journal of Impotence Research 15, no. 1 (2003): 38–43. http://dx.doi.org/10.1038/sj.ijir.3900945.
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Ushas, P., V. Ravi, J. M. Painatt, and P. P. Nair. "Pneumosinus dilatans multiplex associated with hormonal imbalance." Case Reports 2013, aug26 1 (2013): bcr2013010345. http://dx.doi.org/10.1136/bcr-2013-010345.
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Sahoo, Subhrajeet Narayan. "Effect of Hormonal Imbalance on Jaw Growth." Indian Journal of Public Health Research & Development 10, no. 11 (2019): 356. http://dx.doi.org/10.5958/0976-5506.2019.03491.0.
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BOSCHERT, SHERRY. "A Hormonal Imbalance May Underlie Recalcitrant Obesity." Rheumatology News 6, no. 2 (2007): 31. https://doi.org/10.1016/s1541-9800(07)70153-9.
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ARSHAD, A., M. ATIF, M. HUZAIFA, et al. "EFFECTS OF HORMONAL THERAPY IN TRANSGENDERS." Biological and Clinical Sciences Research Journal 2024, no. 1 (2024): 948. http://dx.doi.org/10.54112/bcsrj.v2024i1.948.
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People who change their gender after birth are known as transgender people. They underwent surgical transformation along with hormonal therapy. Hormonal imbalance is the most common phenomenon in the transgender community due to hormonal therapy and other related issues. Hormonal therapy is essential for gender transformation, but this therapy poses several risks to the individual who is taking this therapy. Transgender people who are under hormonal therapy are more at risk of cardiovascular disorders as certain hormones like estrogen and testosterone, besides their intended function, also induce side effects, due to which individuals taking these hormones become more prone to cardiovascular disorder, irregular blood pressure, brain function, and structure start changing. The cross-sex hormone therapy is also associated with brain tumors, changes in body mass index, and several skin conditions. Such hormones also affect bone density in different individuals due to changes in the deposition pattern of calcium into the bone under hormonal control. Hormonal therapy causes certain metabolic disorders as well, and certain hormones interact with other hormones in a different way when they are not naturally produced in the body. The voice of such people undergoing gender transformation also changes due to the testosterone level. This review summarizes some aspects of hormonal therapy, but whether or not a person undergoes such transition is their choice.
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Warren, W. H., D. D. Caldarelli, I. Lee, H. Javid, and V. E. Gould. "Neuroendocrine Markers in Paragangliomas of the Head and Neck." Annals of Otology, Rhinology & Laryngology 94, no. 6 (1985): 555–59. http://dx.doi.org/10.1177/000348948509400606.
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Eighteen paragangliomas of the head and neck (11 carotid body tumors, four glomus tympanicum tumors, three glomus jugulare tumors) were studied retrospectively. Tissue from each of these tumors was immunostained for the presence of serotonin, a variety of neuropeptide hormones, and the enzyme neuron-specific enolase (NSE). Seven tumors were studied by electron microscopy. The clinical and laboratory records were reviewed for evidence of endocrine activity or metabolic imbalance. All tumors displayed diffuse and intense immunostaining for NSE. In addition, a wide variety of hormonal substances could be identified. Those most frequently demonstrated were serotonin and leu-enkephalin. Ten of the 11 carotid body tumors demonstrated immunoreactivity for multiple hormones. By electron microscopy all tumors contained a heterogeneous population of membrane-bound neurosecretory granules. None of these tumors was associated with a clinically apparent endocrine syndrome. We conclude that paragangliomas of the head and neck are neuroendocrine tumors that are capable of synthesizing a variety of hormonal substances. These hormonal substances rarely elicit a clinically apparent endocrine or metabolic imbalance. All of the tumors demonstrated immunostaining for NSE. Future studies on serum levels of NSE may provide useful diagnostic and follow-up data.
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x, Chetna. "Efficacy of Complete Repertory in Management of Hormonal Imbalance in Females." International Journal of Science and Research (IJSR) 13, no. 8 (2024): 392–93. http://dx.doi.org/10.21275/sr24805074532.
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Jorda, Romeo Jr, Kit Erick Bartolome, Christopher Buban, et al. "Ovulation hormonal imbalance recognition system using saliva’s conductivity analysis based on potentiometric method." Indonesian Journal of Electrical Engineering and Computer Science 16, no. 1 (2019): 176. http://dx.doi.org/10.11591/ijeecs.v16.i1.pp176-183.
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<span lang="EN-US">Hormonal imbalance is often pointed out by medical experts to be the cause of menstrual irregularity, a common problem of women. This study aims to develop a device that would determine if a patient has hormonal imbalance by testing saliva’s conductivity onto the device for 28 consecutive days, thus, determining the cause of the patient’s menstrual irregularity. To test the accuracy of the device, the researchers selected three women residing in one home to use the device. To determine if a woman has hormonal imbalance, the data, when plotted in a chart, should have a sudden peak. However, data can’t be analyzed through visual assumptions only. Therefore, the data is analyzed through sample standard deviation. If one data is higher or lower than the sum and difference of the sample standard deviation and the mean, the woman is negative in hormonal imbalance. Comparing the result from the device and from the blood test, it is concluded that the results from the device matched the results from the blood test and medical expert interpretation.</span>
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Ojoye N. Briggs and Kemzi N. Elechi-Amadi. "Effects of an herbal formulation on lead acetate-induced hormonal imbalance in female albino rats." GSC Biological and Pharmaceutical Sciences 31, no. 2 (2025): 033–39. https://doi.org/10.30574/gscbps.2025.31.2.0168.
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Hormonal imbalance is a situation in which there is too little or too much of one or many hormones in the body, and this has negative effect on certain physiological processes including reproduction. Aim: This study evaluated the effects of an herbal formulation on lead acetate-induced hormonal imbalance in female albino rats Methodology: The herbal formulation was prepared by mixing 5 g each of bay leaf, scent leaf, clove and cheese wood, and making an aqueous extract using the mixture. Thirty-five (35) female albino rats were used for this study. They were grouped into 5 groups of 7 rats each as follows: group 1(negative control), group 2(positive control), Group 3 (treated with 500 mg/kg of herbal formulation as low dose), Group 4 (treated with 1000 mg/kg of herbal formulation as high dose), Group 5 (treated with 81 mg/kg of Vitamin E as standard drug). Rats in groups 2-5 were induced with hormonal imbalance using 60 mg/kg. Groups 3-5 were treated as indicated for 28 days. Results: The mean hormonal levels in the rats in the treated groups were significantly higher (P<0.05) than the levels in the positive control group. However, the mean hormonal levels in the treated groups, were significantly lower (P<0.05) than the mean levels in the negative control group, except for testosterone levels in the Vitamin E group. The LH/FSH ratios were significantly higher (P<0.05) in the negative control group, compared to the other groups. Testosterone/estradiol ratio was significantly higher (P<0.05) in the negative control group, compared to the other groups, except the vitamin E administered group. The progesterone/estradiol ratio was significantly raised (P<0.05) in the positive control group compared to the other groups. The liver enzymes were significantly lower (P<0.05) in the groups treated with the herbal formulation and vitamin E, compared with the levels in the positive and negative control groups Conclusion: These finding indicate that the herbal formulation and vitamin E exhibited beneficial effects in restoring hormone levels and attenuating inflammation. Therefore, the herbal formulation can be considered to possess ameliorative potential in hormonal imbalance.
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Kurzawa, Małgorzata. "The effect of diet and supplementation on the effectiveness cosmetology therapy in women with polycystic ovary syndrome." Aesthetic Cosmetology and Medicine 10, no. 3 (2021): 119–23. http://dx.doi.org/10.52336/acm.2021.10.3.04.
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Diseases of the endocrine glands and disorders related to the production of hormones very often lead to skin problems. The impact of everyday diet on disorders and regulation of the hormonal balance becomes more and more noticeable. One of the most frequently diagnosed endocrinopathy in recent years, which is also reflected in the skin, is polycystic ovaries or polycystic ovary syndrome. The aim of the article was to draw attention to the relationship between improper eating habits and hormonal imbalance, which may result in skin defects. Imbalance in the secretion of androgens can lead to disturbances in the functioning of the sebaceous unit, and thus to seborrheic skin diseases or hirsutism. Appropriate pharmacotherapy, diet and supplementation should help to reduce secretion of androgens and their activity in the hair follicles and lower the circulation of free testosterone, but further research is still needed.
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Krishnan, Abhaya, and Sridhar Muthusami. "Hormonal alterations in PCOS and its influence on bone metabolism." Journal of Endocrinology 232, no. 2 (2017): R99—R113. http://dx.doi.org/10.1530/joe-16-0405.
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According to the World Health Organization (WHO) polycystic ovary syndrome (PCOS) occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is 12.2% according to the Indian Council of Medical Research (ICMR). The National Institute of Health has documented that it affects approximately 5 million women of reproductive age in the United States. Hormonal imbalance is the characteristic of many women with polycystic ovarian syndrome (PCOS). The influence of various endocrine changes in PCOS women and their relevance to bone remains to be documented. Hormones, which include gonadotrophin-releasing hormone (GnRH), insulin, the leutinizing/follicle-stimulating hormone (LH/FSH) ratio, androgens, estrogens, growth hormones (GH), cortisol, parathyroid hormone (PTH) and calcitonin are disturbed in PCOS women. These hormones influence bone metabolism in human subjects directly as well as indirectly. The imbalance in these hormones results in increased prevalence of osteoporosis in PCOS women. Limited evidence suggests that the drugs taken during the treatment of PCOS increase the risk of bone fracture in PCOS patients through endocrine disruption. This review is aimed at the identification of the relationship between bone mineral density and hormonal changes in PCOS subjects and identifies potential areas to study bone-related disorders in PCOS women.
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Kishanrao, Suresh. "TRT – The Best Treatment for Balancing Testosterone in Middle Aged Men." Series of Endocrinology, Diabetes and Metabolism 5, no. 2 (2023): 56–67. http://dx.doi.org/10.54178/jsedmv5i2003.
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Balance is critical to many aspects of life. Work-life balance ensures that we have time to enjoy the fruits of our labor. Hormones control bodily processes like – metabolism, homeostasis, growth and development, sexual function, reproduction, sleep-wake cycle, and mood. Most men see a gradual and progressive decline of testosterone, the primary male sex hormone, starting around age 30, at a rate of 1–2% per year, though in some men, the decline is faster than the body can adequately compensate. In these cases, the fallout can be felt throughout the body with symptoms that are both disruptive and inconvenient. It is produced in the testicles and the adrenal glands but regulated by the hypothalamic-pituitary-gonadal (HPG) axis, a feedback system that responds to circulating hormone levels. Hormonal imbalance in men closely parallels the aging process. The most effective way of balancing male hormones is using testosterone replacement therapy (TRT). Generally, a value < 300 ng/dL is considered low, leading to a condition called hypogonadism. While one-third of Indian men above 40 years of age suffer from hypogonadism, the proportion of them as appropriate candidates for testosterone therapy (TTh) is not clear, not only in India but also in most countries. TTh helps reverse the effects of hypogonadism, but it’s unclear if it would benefit otherwise healthy older men. Primary care physicians encounter clinical conditions of hormonal imbalances in males, such as precocious puberty, delayed puberty, and hypogonadism, in general practice, needing specialists’ consultation and guidance for their management. Quoting half a dozen case reports of hormonal imbalance and their management, this article provides the evidence to prescribe or not to prescribe hormones for men. Materials and Methods: Sample cases of precocious puberty, delayed puberty, male hypogonadism (MH) (general, diabetic, and intracranial hypertension), and a case of complication of TTh cases in adults and how they were diagnosed and managed. Literature review for current evidence for TTh in men globally and in Indian practices.
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Goel, Meetu, Pooja Gautam, and Juthika Gogoi. "A case of hyperthyroidism treated with individualised homoeopathic medicine: A case report." Journal of Integrated Standardized Homoeopathy 7 (January 21, 2025): 160–65. https://doi.org/10.25259/jish_39_2023.
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Hyperthyroidism is a common disorder where the thyroid gland produces and secretes excess thyroid hormone. Hyperthyroidism is associated with significant acute and chronic morbidity. Early recognition and timely management of the condition are required for maintaining health. Homoeopathy has an effective treatment for hormonal imbalance, but the documented evidence in support of hyperthyroidism is limited. Here, we present a case of hyperthyroidism which showed significant improvement in reverting the imbalanced hormones to the normal limits in a short span of time with improvement in other symptoms with individualised homoeopathy and causal attribution of treatment outcome was also assessed using Modified Naranjo Criteria. The case report followed the HOM-CASE guidelines for clinical case reporting outcomes.
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Kim, Bo Hye, Yena Joo, Min-Seon Kim, Han Kyoung Choe, Qingchun Tong, and Obin Kwon. "Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones." Endocrinology and Metabolism 36, no. 4 (2021): 745–56. http://dx.doi.org/10.3803/enm.2021.405.
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Intermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medical complications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels, cardiac and brain function, and other health benefits, in addition to weight loss. However, concerns have also been raised on side effects including muscle loss, ketosis, and electrolyte imbalance. Of particular concern, the effect of intermittent fasting on hormonal circadian rhythms has received little attention. Given the known importance of circadian hormonal changes to normal physiology, potential detrimental effects by dysregulation of hormonal changes deserve careful discussions. In this review, we describe the changes in circadian rhythms of hormones caused by intermittent fasting. We covered major hormones commonly pathophysiologically involved in clinical endocrinology, including insulin, thyroid hormones, and glucocorticoids. Given that intermittent fasting could alter both the level and frequency of hormone secretion, decisions on practicing intermittent fasting should take more considerations on potential detrimental consequences versus beneficial effects pertaining to individual health conditions.
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Bono, Roberto, Giulia Squillacioti, Federica Ghelli, et al. "Oxidative Stress Trajectories during Lifespan: The Possible Mediation Role of Hormones in Redox Imbalance and Aging." Sustainability 15, no. 3 (2023): 1814. http://dx.doi.org/10.3390/su15031814.
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Aging, a natural multifactorial process, increases Oxidative Stress (OS) and inflammatory responses. Sexual hormones could upregulate OS during lifespan, with opposite systemic effects: anti-oxidant protection and cellular pro-oxidant toxicity. Hormonal changes are crucial phases in human growth and aging, but their mediating role on OS is still incomplete. The main purpose of this work was to analyze the trend of OS during the lifespan and, in particular, during puberty and menopause. Data from standardized questionnaires and biological OS measurements (15-F2t-Isop) of 815 subjects (7–60 years old) from five previous studies (2009–2015) were analyzed. The age variable was categorized into two hormonal age windows: puberty and menopause. A regression model was performed to assess the association between 15-F2t-Isop and the hormonal age window, sex, weight, and smoking habits. The results showed a significant V-shape decrease of OS levels both during puberty [OR = −0.06 95% CI −0.07–−0.04, p = 0.41] and in menopause [OR = −1.01 95% CI −1.5–−0.5, p < 0.001], but only in females. Our results support the view that hormones, and specifically estrogen, could modulate OS, especially during puberty and menopause. The V-shape decreasing trend of OS may be related to intrinsic characteristics of estrogen, which is able to modulate and upregulate OS pro- and anti-oxidant mechanisms.
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Abid, Mohammad Usman, Akif Saeed Ch, Sabeen Iqbal, et al. "A SYSTEMATIC REVIEW OF ENVIRONMENTAL TOXINS AND HORMONAL IMBALANCE." Insights-Journal of Life and Social Sciences 3, no. 3 (Social) (2025): 124–29. https://doi.org/10.71000/jzjkeh27.
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Background: Environmental toxins, particularly endocrine-disrupting chemicals (EDCs), have been increasingly implicated in the dysregulation of hormonal systems, contributing to a growing burden of endocrine disorders. Despite mounting concern, the literature remains fragmented with inconsistencies in exposure definitions and outcome measures, highlighting the need for a consolidated evidence base to clarify these associations. Objective: This systematic review aimed to evaluate and synthesize current evidence on the relationship between environmental toxin exposure and hormonal imbalance in human populations, with a focus on mechanisms, health outcomes, and clinical relevance. Methods; A systematic review was conducted in accordance with PRISMA guidelines. Four databases (PubMed, Scopus, Web of Science, and Cochrane Library) were searched for articles published between 2018 and 2024 using a combination of terms related to “environmental toxins,” “endocrine disruptors,” and “hormonal imbalance.” Studies were included if they examined human populations and reported hormonal or endocrine-related outcomes. Risk of bias was assessed using the Newcastle-Ottawa Scale and the Cochrane Risk of Bias Tool, and data were synthesized qualitatively due to methodological heterogeneity. Results: Eight studies met the inclusion criteria. The findings consistently demonstrated that exposure to environmental toxins such as heavy metals, pesticides, and industrial chemicals is associated with epigenetic changes, reproductive hormone disruption, and increased risk of conditions such as PCOS and hormone-sensitive cancers. Notably, synergistic effects from multiple contaminants were also identified. While evidence was moderate to strong across studies, variability in design and exposure measurement limited the ability to conduct meta-analysis. Conclusion: This review supports a clear link between environmental toxin exposure and hormonal imbalance, underscoring the need for clinical awareness and public health policies that minimize exposure risks. Future research should prioritize longitudinal studies with standardized exposure metrics to better establish causality and guide regulatory action.
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Ms. Shweta Kushwah, Ms Shweta Kushwah, and Navdeep Jaisawal Navdeep Jaisawal. "Formulation and Evaluation of herbal chocolate for treating hormonal imbalance." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 624–32. https://doi.org/10.35629/4494-1003624632.
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Hormonal imbalances are increasingly prevalent due to stress, lifestyle changes, and environmental factors, especially among woman of reproductive age. The present study focuses on the formulation and evaluation of a novel herbal chocolate incorporating withaniasomnifera (Ashwagandha) to address hormonal irregularities naturally. Ashwagandha, a well – known adaptogenic herb, is recognized for its potential to modulate cortisol levels and support endocrine function. The prepared formulation was evaluated for its organoleptic properties, stability, and consumer acceptability. Preliminary observations indicated a favorable response in terms of palatability and shelf – life. The study suggests that herbal chocolates could serve as a convenient and appealing delivery system for herbal remedies, offering an alternative route for promoting hormonal balance through functional foods. Further clinical evaluations are recommended to validate the therapeutic efficacy of the formulation
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Nazia, Yaqoob, and Zahid Ambreen. "Obsessive-Compulsive Tendencies & Self-Concept Clarity Among Females With and Without Hormonal Imbalance." Journal of Research & Health 11, no. 5 (2021): 297–304. http://dx.doi.org/10.32598/jrh.11.5.1916.1.
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Background: The role of hormones in the female body is well known in reproductive age. Several studies have been conducted regarding hormonal fluctuations and their association with obsessive-compulsive disorder, but the role of psychological issues relevant to it has been ignored and only hormonal fluctuation and its impact were the target. Thus, the main purpose of this study was to examine the relationship between Self-Concept Clarity (SCC) and obsessive-compulsive tendencies (Obsessive-Compulsive Concerns about Cleanliness (OCC) and Obsessive-Compulsive concerns about Harm and Injury (OCHI)). Another objective was to identify the difference between SCC, OCC, and OCHI in healthy and unhealthy females. Methods: A sample of (N=210) females, an equal number of healthy and unhealthy females, from different hospitals and the general population, with a mean age of 21 years, was selected by using convenience sampling technique as a type of non-probability sampling. Study participants were selected from the same city. Results: Comparison of healthy and unhealthy females revealed high levels of SCC and obsessive-compulsive tendencies among unhealthy females and also a significant positive correlation was found between these constructs. Conclusion: The females with irregular hormonal fluctuations develop obsessive-compulsive tendencies and these people are most sensitive to unimportant affairs, even sensitive to themselves that might create clarity in their self-concept.
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Jitendra, Sunte. "The Glands Activation Methods and Practices in Human Body." Research and Reviews in Intensive and Critical Care Nursing 1, no. 2 (2023): 15–18. https://doi.org/10.5281/zenodo.10089353.
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<i>The major types of human body glands are seven, which release seven hormones that make the human body as stable as required in day-to-day life. This paper mainly focuses on how the human body will be in stable equilibrium, where and when the body will not influence diseases, and what are the methods to gain the activation of glands to release hormones in the whole body. There are mainly seven glands, namely the hypothalamus, pituitary, thyroid, parathyroid, adrenals, pineal body, the ovaries, and the testes. Energy from the universe obtained while maintaining equilibrium of all three doshas (kapha, vaata, and pitta). Kapha imbalance problems are lack of knowledge, pitta imbalance as attaching nature of behavior, and finally vaata imbalance as desire of human body personalities. Hormone imbalances, diseases like age, sex, voice, fertility, thyroid, etc. activation of glands by humoral stimuli, hormonal stimuli, and neural stimuli, etc. The healing of any problems by tuning the fork at a particular amplitude of frequencies generally results in universe energy obtained by frequency at 540 Hz. From these human body parts, like the heart, kidney, lever, stomach, and nerves, all will get the energy of vibration properly at a particular frequency in Hz. Some unwanted rattling sounds will cause severe conditions, which may come from leg joints or knee joints, especially in elderly people. Some Ayurvedic treatments, like oil massaging, give better results by enhancing the required stiffness in the human body, which directly controls unwanted sound coming from human body parts.</i>
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Nahleh, Zeina. "Breast cancer, obesity and hormonal imbalance: a worrisome trend." Expert Review of Anticancer Therapy 11, no. 6 (2011): 817–19. http://dx.doi.org/10.1586/era.11.67.
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Hetzl, A. C., F. Montico, R. M. Lorencini, L. A. Kido, E. M. Cândido, and V. H. A. Cagnon. "Prostatic microenvironment in senescence: fibroblastic growth factors × hormonal imbalance." Histochemistry and Cell Biology 141, no. 5 (2013): 531–42. http://dx.doi.org/10.1007/s00418-013-1173-y.
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Nurmayani, Winda, Misroh Mulianingsih, and Ni Ketut Ika Mustika Suarnaya. "Perbedaan Kualitas Seksual pada Wanita Akseptor KB Hormonal dengan KB Non-Hormonal." Jurnal Kebidanan dan Kesehatan Tradisional 5, no. 2 (2020): 84–93. http://dx.doi.org/10.37341/jkkt.v5i2.155.
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Background: Sexual intercourse in the family is the peak of harmony, therefore both parties must be able to enjoy it together. Sex dissatisfaction can lead to differences of opinion, disputes and ultimately divorce. Hormonal contraception has side effects, one of which is an imbalance of the hormones estrogen and progesterone which can cause changes in sexual activity. Each type of family planning has its own side effects, but in most cases a decrease in sexual desire is a side effect that can be found in every use of the type of family planning. The purpose of this study was to determine differences in sexual quality in female hormonal and non-hormonal family planning acceptors.Methods: Descriptive analytic type of research with a comparative design using the Case Control approach, a sample of 68 Wus which is a hormonal and non-hormonal family planning acceptor. Simple Random Sampling sampling technique and observation sheet instrument and SQOL-F questionnaire. This research uses Chi Square data analysis.Results: Chi Square Continuity Corrections test results showed significant results P = 0.000 (P <0.1), meaning that P value 0.000 is smaller than 0.1 there are differences in sexual quality in female hormonal and non-hormonal KB acceptors.Conclusion: Most non-hormonal family planning acceptors have good sexual qualities while hormonal birth control acceptors mostly have moderate sexual quality.
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V S, Aswathy, and Vineetha Sankar P. "Comparative Study on AI Technology in PCOS Diagnosis." International Journal for Research in Applied Science and Engineering Technology 11, no. 5 (2023): 846–48. http://dx.doi.org/10.22214/ijraset.2023.51615.
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Abstract: With the help of AI, healthcare systems can process massive volumes of clinical data with pinpoint accuracy. Polycystic ovarian syndrome (PCOS) is a disorder that affects women of reproductive age and causes hormonal imbalances, and it is a prevalent health issue among young women. A hormonal imbalance is the root cause of menstrual irregularities. Women with polycystic ovary syndrome are more likely to experience significant weight gain, increased facial hair, acne, hair loss, skin tone changes, and irregular menstruation, which in rare cases can result in infertility. Since a correct diagnosis is vital to effective treatment, this essay will examine and contrast several machine learning methods. We will also talk about an artificial intelligence method that combines aspects of both heterogeneous ML and Deep Learning
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Yousaf Farooq, Syed Muhammad, Syed Amir Gilani, Syeda Khadija Tul Sughra, et al. "Sonographic Relation between Adnexal Masses and Endometrial Thickness in Infertile Females with Hormonal Imbalance." Pakistan Armed Forces Medical Journal 73, no. 3 (2023): 646–49. http://dx.doi.org/10.51253/pafmj.v73i3.7379.
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Objective: To determine the sonographic relation between adnexal masses and endometrial thickness in infertile females with hormonal imbalances.
 Study Design: Cross-sectional analytical study.
 Place and Duration of Study: Department of Radiology, Gilani Ultrasound Center, Jamiat Hospital & Green Town Clinic, Lahore Pakistan, from Mar 2019 to Jan 2020.
 Methodology: In this study, 150 infertile females with adnexal masses, aged 18 to 45, were included. Data were collected according to the age, adnexal masses, endometrium thickness, and type of infertility hormonal levels. The endometrium thickness was measured in the sagittal plane at the thickest echogenic area from one basal endometrial interface across the endometrial canal to the other basal surface.
 Results: The mean age was 32.55±6.33 years. Out of 150 patients, 97 patients with abnormal and 53 were with normal hormonal levels. Follicular cysts (33%), Polycystic ovarian syndrome (29.9%) and 23.7% hemorrhagic cysts were found with abnormal hormonal levels.
 Conclusion: There was a significant correlation between adnexal masses and endometrial thickness in infertile females with abnormal hormonal levels.
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Turdalieva, B., M. Asheraliev, and G. Maimerova. "Hormonal Status in Children With Acute Cutaneous Allergic Diseases in the Kyrgyz Republic." Bulletin of Science and Practice 6, no. 1 (2020): 138–44. http://dx.doi.org/10.33619/2414-2948/50/15.
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The article presents the results of a hormonal examination of 69 children with acute skin allergic diseases, who received hospital treatment at the National Center for the Protection of Motherhood and Childhood. This made it possible to identify the features of hormonal shift in various manifestations of urgent skin allergic diseases in children. A link has been established between the clinical severity of the disease hormonal imbalance.
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Kim, Tae Won, Jong-Hyun Jeong, and Seung-Chul Hong. "The Impact of Sleep and Circadian Disturbance on Hormones and Metabolism." International Journal of Endocrinology 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/591729.
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The levels of several hormones fluctuate according to the light and dark cycle and are also affected by sleep, feeding, and general behavior. The regulation and metabolism of several hormones are influenced by interactions between the effects of sleep and the intrinsic circadian system; growth hormone, melatonin, cortisol, leptin, and ghrelin levels are highly correlated with sleep and circadian rhythmicity. There are also endogenous circadian mechanisms that serve to regulate glucose metabolism and similar rhythms pertaining to lipid metabolism, regulated through the actions of various clock genes. Sleep disturbance, which negatively impacts hormonal rhythms and metabolism, is also associated with obesity, insulin insensitivity, diabetes, hormonal imbalance, and appetite dysregulation. Circadian disruption, typically induced by shift work, may negatively impact health due to impaired glucose and lipid homeostasis, reversed melatonin and cortisol rhythms, and loss of clock gene rhythmicity.
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О.М., Proshchenko, and Ventskivska I.В. "EFFECT OF HYSTERECTOMY ON THE FUNCTION OF SAVED OVARIES AND CORRECTION OF HORMONAL IMBALANCE." Reproductive Health of Woman, no. 3 (May 31, 2022): 18–26. https://doi.org/10.30841/2708-8731.3.2022.262367.
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<em><strong>The objective:</strong></em> to assess the hormonal disorders in patients after the radical treatment for leiomyoma and to develop the therapeutic options for correction. <em><strong>Materials and methods.</strong> </em>The clinical and laboratory assessment of postoperative course after leiomyoma surgery in 160 women of reproductive age was carried out. The following groups of patients were formed: I group – 90 patients after vaginal hysterectomy (HE) with opportunistic salpingectomy and ovarian preservation, II group – 70 patients after abdominal HE with opportunistic salpingectomy and ovarian preservation. The control group included 50 women of reproductive age with asymptomatic leiomyoma. Then the following groups were formed to assess the effectiveness of the proposed medical correction program: the main group – 46 patients after vaginal HE with fallopian tubes and 36 persons after abdominal HE with fallopian tubes – received the proposed medical correction program, and the comparison group – 44 and 34 individuals after vaginal and abdominal HE with opportunistic salpingectomy and ovarian preservation, respectively, with standard approach for postoperative and rehabilitative periods. The diagnostic program included the assessment of hormonal level, post-hysterectomy syndrome degree by modified menopausal index using survey, urogenital and sexual dysfunction, and the indicators of vulvovaginal atrophy according to the Barlow scale. <em><strong>Results.</strong></em> Neurovegetative symptoms were observed in 36,7 % patients in the I group and 48.6 % - II group, vegetative-vascular symptoms – 46.7 % and 62.3 %, respectively. Insomnia was characterized by the sleep process disorders, the preservation of the feeling of fatigue after waking up. It is necessary to mention that an increase in the proportion of cardiovascular diseases up to 36 months after surgery (hypertension, dyshormonal cardiomyopathy and their combinations, 23.1 % were diagnosed with dyshormonal mastopathy, the women complained on arthralgia, morning joint stiffness, ostealgia twice more. The assessment of sexual disorders and manifestations of urogenital tract dysfunction allowed to indicate the most significant rate of dysuria complains in 72.9 % of cases in the II group after classical abdominal HE. Up to 36 months after surgery the subclinical hypothyroidism was found in 62.2 % of women in the I group and 31.4 % – II group, clinically significant hypothyroidism – in 21.1 % and 55.7 %, respectively. In the half of the cases the hormonal imbalance like hypoesrogenia was determined up to 36 months of monitoring without statistically significant differences between groups of different HE methodic. The main factor was patient’s age in which endocrine, vegetative-vascular disorders and the clinical manifestations of psychosomatic are developed in a larger percentage of significantly earlier in women of late reproductive age. The use of proposed program of therapeutic options after HE with ovarian preservation allowed to provide a tendency of the estradiol, progesterone and testosterone levels normalization, prolactin and cortisol concentrations were close to the reference values. Estradiol concentration in the women in main group increased, although it remained significantly below the age normal indices, and the most significant normalization of theses parameters were determined in women who received hormonal replacement therapy. Clinically positive effect in patients on the severity of neurovegetative and psychoemotional manifestations on the background of differentiated treatment was observed after 3 months from the beginning of therapy. <em><strong>Conclusions.</strong></em> The obtained results suggest that the optimization of the treatment program with the the proposed drugs in women in the groups leads to relative optimization of hormonal status and initiation of compensatory-adaptive responses of the organism, which improves the quality of life and eliminates symptoms of hypoestrogenism.
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Winderlich, M. E. "INFLUENCE OF HORMONES (HORMONAL STATUS) ON THE MUSCLE-LIGGING APPARATUS INPREGNANT WOMEN." Journal of Volgograd State Medical University 80, no. 4 (2021): 8–11. http://dx.doi.org/10.19163/1994-9480-2021-4(80)-8-11.
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e. Imbalance of hormones in a woman's body provokes a number of disorders of the body's functions, which affects her emotional and physical well-being. Purpose – to study the current state of the problem of changes in the musculo-ligamentous apparatus in pregnant women against the background of changes in their hormonal status. Material and methods. A systematic analysis of the main hormonal changes occurring in a woman's body during childbearing, and the results of research by Russian and foreign experts in this area. Results and discussion. It has been established that to date, in Russian and foreign practice, the number of studies that show the correlation between changes in the hormonal background of a pregnant woman and her musculo-ligamentous apparatus is still insignificant and is extremely fragmented. Conclusion. It is concluded that it is necessary to expand the boundaries of experimental studies and conduct a detailed analysis of clinical cases of the onset and exacerbation of musculo-ligamentous pathologies in a situation of a change in the hormonal status of a woman against the background of her pregnancy.
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Abaev, Z. M., O. V. Sagina, and E. Y. Zabalueva. "The effectiveness of treatment of chronic generalized periodontitis with the use of substitution therapy in women with hormonal status disorders." Medical alphabet, no. 1 (March 3, 2024): 20–24. http://dx.doi.org/10.33667/2078-5631-2024-1-20-24.
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Relevance. In clinical observations, a combination of somatic pathology with various forms of periodontal tissue diseases has long been established. Hormonal status is of particular interest in this direction, since hormonal failure causes disturbances in the hormonal background of a person.Goal. The aim is to increase the effectiveness of treatment of women with chronic generalized periodontitis on the background of hormonal imbalance by correcting the receptor status of the gingival epithelium.Materials and methods of research. The research methodology provided for the integration of clinical, laboratory, histological and immunohistochemical methods. To realize the purpose of the study, a systematic approach was used, which was based on the analysis of the content of interrelated sources of primary information. The object of the study were women aged 18 to 59 years, who were assessed for periodontal status against the background of gynecological pathology and hormonal imbalance with the use of substitution therapy.Conclusions. The inclusion in the complex treatment of periodontal tissue diseases of drugs with receptor-modulating and anti-inflammatory effect normalizes the work of the receptor apparatus of the gingival epithelium, which increases the effectiveness of the treatment of periodontal pathology.
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DZYUBAILO, ANNA V., and VYACHESLAV S. LOTKOV. "NICOTINE ADDICTION AND HORMONAL IMBALANCE IN PREGNANT SMOKERS WITH VARYING DEGREES OF COPD SEVERITY." Bulletin of Contemporary Clinical Medicine 16, no. 2 (2023): 18–22. http://dx.doi.org/10.20969/vskm.2023.16(2).18-22.
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Introduction. The relationship between the degree of nicotine addiction and the functional state of the thyroid gland, the adrenocorticotropic hormone-cortisol system and hormone imbalance in pregnant women smokers with chronic obstructive pulmonary disease was studied. Aim. The aim of the study was to identify and evaluate the relationship between the degree of nicotine dependence and hormonal imbalance of the thyroid gland, cortisol and progesterone in pregnant smokers with varying degrees of chronic obstructive pulmonary disease severity. Material and methods. The study is based on the results of studying changes in blood hormone indicators in 107 smoking women with chronic obstructive pulmonary disease and 136 non-smoking women in different trimesters of pregnancy observed in the antenatal clinic. The control group consisted of healthy non-smoking patients. The diagnosis of chronic obstructive pulmonary disease was made based on the clinical recommendations of the Russian Respiratory Society (2021). The reliability of the results was evaluated using parametric statistics methods. The data obtained were processed using the Statistica 10 program, Microsoft Excel 2010. Results and discussion. The presented data revealed the presence in smokers of a statistically significant and very close relationship between the degree of nicotine dependence and the indicators of the imbalance of the hormones studied in all trimesters of pregnancy, with maximum values in the third trimester.This is due to the fact that it is in the third trimester of pregnancy that the maximum increase in the indicators of all studied hormones occurs, even if at the initial stage of pregnancy the indicator could be less than the lower limit of the reference interval, as in the case of thyroid-stimulating hormone.Conclusion. Nicotine addiction creates environment for the development of endocrine imbalance of thyroid hormones, adrenocorticotropic hormone, cortisol and progesterone.
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Zlosa, Mihaela, Barbara Grubišić, Luka Švitek, et al. "Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients." International Journal of Molecular Sciences 25, no. 18 (2024): 9856. http://dx.doi.org/10.3390/ijms25189856.
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Sodium imbalance is a common electrolyte disturbance in COVID-19, often linked to disruptions in hormonal regulation. This review explores the relationship between sodium dysregulation and endocrine disturbances, particularly focusing on primary and secondary hypothyroidism, hypocortisolism, and the renin–angiotensin–aldosterone system (RAAS). Hypocortisolism in COVID-19, due to adrenal insufficiency or secondary to pituitary dysfunction, can lead to hyponatremia through inadequate cortisol levels, which impair renal free water excretion and enhance antidiuretic hormone (ADH) secretion. Similarly, hypothyroidism is associated with decreased renal blood flow and the glomerular filtration rate (GFR), which also increases ADH activity, leading to water retention and dilutional hyponatremia. Furthermore, COVID-19 can disrupt RAAS (primarily through its interaction with the angiotensin-converting enzyme 2 (ACE2) receptor), diminishing aldosterone secretion and further contributing to sodium loss and hyponatremia. These hormonal disruptions suggest that sodium imbalance in COVID-19 is multifactorial and warrants further investigation into the complex interplay between COVID-19, endocrine function, and sodium homeostasis. Future research should focus on understanding these mechanisms to develop management algorithms that address both sodium imbalance and underlying hormonal disturbances in order to improve prognosis and outcomes in COVID-19 patients.
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Bhalerao, Anuja, and Ivan Aranha. "Polycystic Ovarian Syndrome (PCOS), A Distress of Female Reproductive Health." Shanlax International Journal of Arts, Science and Humanities 8, S1-Feb (2021): 46–53. http://dx.doi.org/10.34293/sijash.v8is1-feb.3930.
Full textAbstract:
Women of reproductive age are suffering from severe hormonal imbalance due to polycystic ovarian syndrome (PCOS).Clinical manifestations of PCOS are diverse including hyperandrogenism, anovulation, infertility and increased risk of metabolic diseases besides psychosocial dysfunction.Additionally, PCOS leads to various other disturbances such as glucose tolerance, cardiovascular disease, dyslipidemia, obesity and metabolic disturbances. Environmental pollutants and Xenobiotic compounds cause changes in gut microbiota, which further affects metabolism causing metabolic disturbances may lead to PCOS.Various metabolic anomalies resulting from interaction with xenobiotic compounds and environmental pollutants contribute for hormonal imbalance. It is an interlinked vicious circle affected by epigenetic and environmental parameters.Epigenetic approach and molecular analysis of genes involved in PCOS is essential for specific treatment.Biochemical markers like assessment of hormones(hyperandrogenism)and ultrasound (in patients above twenty years of age)used as diagnostic parameters for detection of PCOS. Adaptinga healthy lifestyle and minimal exposure to xenobiotic compounds and resetting the disturbed sleep cycle will benefit the patient. Study of molecular markers will help in treating the PCOS in a better manner. This review focuses on important parameters of pathophysiology, which will help in understanding andcreating awarenesson PCOS.