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Dissertations / Theses on the topic 'Horse, selenium, glutathione peroxidase'

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Published: 4 June 2021

Last updated: 1 February 2022

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1

Brummer, Mieke. "THE INFLUENCE OF SELENIUM STATUS ON IMMUNE FUNCTION AND ANTIOXIDANT STATUS IN THE HORSE." UKnowledge, 2012. http://uknowledge.uky.edu/animalsci_etds/7.

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Selenium (Se) has received a lot of attention for its antioxidant and immune modulating properties. Yet, comparably few studies have focused on the horse. Therefore the objectives of this research were to evaluate the influences of Se status on immune function and antioxidant defense in horses. Twenty eight horses were allocated to one of 4 dietary Se treatments: low (LS), adequate (AS), high organic (SP) and high inorganic (SS). First, horses assigned to LS, SP and SS were depleted of Se and received a low Se diet (0.07 ppm Se) for 35 wk, while AS received an adequate Se diet (0.14 ppm Se). D

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2

Knight, Simon Alexander Bowles 1961. "The use of anti-glutathione peroxidase antibodies in the study of selenium-dependent glutathione peroxidase." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276906.

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Liver glutathione peroxidase activity is affected by changes in selenium (Se) status. To investigate the effect of Se status on GSH-Px protein we prepared antibodies against rat liver GSH-Px and used them in an ELISA. The immunoreactivity of the anti-GSH-Px antibodies against GSH-Px was both tissue and species specific. When rats were depleted of Se, liver GSH-Px activity decreased exponentially to zero with a half-life of 2.8 d. Liver GSH-Px protein also decreased exponentially, but not to zero, with a longer half-life of 5.2 d. Dietary repletion of Se-deficient rats with 0.5 mg Se/kg diet in

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3

Huang, Wenhu. "Extracellular glutathione peroxidase purification, immunoassay, nutritional regulation and clinical aspects /." Lund : Lund University Dept. of Applied Nutrition and Food Chemistry, 1996. http://catalog.hathitrust.org/api/volumes/oclc/38100668.html.

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4

Wen, Wu. "UGA-mediated selenium incorporation into glutathione peroxidase 1 and green fluorescent protein /." free to MU campus, to others for purchase, 1998. http://wwwlib.umi.com/cr/mo/fullcit?p9904872.

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5

Ali, Johar. "Performance, tissue selenium concentration and glutathione peroxidase activity as response variables for determining selenium requirements of poultry /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9999267.

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6

Hadley, Kevin B. "Differential regulation of selenoenzymes by SE status in mammals and birds /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3025622.

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7

Rocha, Anna Silvia Penteado Setti da. "Efeito do selenito de sodio na reparação ossea em tibias de ratos irradiados." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290156.

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Orientador: Solange Maria de Almeida<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-04T06:49:17Z (GMT). No. of bitstreams: 1 Rocha_AnnaSilviaPenteadoSettida_D.pdf: 3382405 bytes, checksum: ac0363e76c4f0a9223b1427cc5dcf489 (MD5) Previous issue date: 2005<br>Resumo: Sendo a radiação ionizante causador de efeitos deletérios no processo de reparação tecidual e o selenito de sódio um agente antioxidante, atuando contra os radicais livres no organismo, a realização deste trabalho de pesquisa teve como objetivo

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8

Chada, Sunil. "A Molecular Analysis of Selenium Incorporation into Glutathione Peroxidase: Stop Is Not the End: A Thesis." eScholarship@UMMS, 1989. http://escholarship.umassmed.edu/gsbs_diss/154.

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Selenium is toxic at high doses, yet metabolically essential in trace amounts, and therefore provides an excellent illustration of the rule of paracelsus that "the dose alone determines the poison". The only mammalian selenoprotein of known function is glutathione peroxidase (GPx). This enzyme is expressed ubiquitously, and is responsible for detoxifying peroxides and hydroperoxides which, if left unchecked, may damage important biomolecules such as DNA and membrane fatty-acids. GPx is a homotetramer; each subunit contains one mole atom of selenium incorporated as a selenocysteine residue in

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9

Santos, Larissa Bezerra. "Polimorfismo Pro198Leu no gene que codifica para a glutationa peroxidase 1 e sua relação com o estado nutricional relativo ao selênio de uma população adulta residente no município de Fortaleza, Ceará." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-10092014-114419/.

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O selênio (Se), mineral traço essencial para o ser humano, exerce sua função no organismo por meio de sua participação nas selenoproteínas, dentre as quais destacam-se as glutationas peroxidase (GPx), importantes no sistema de defesa antioxidante. São conhecidas sete isoformas da GPx, sendo a GPx 1 (citosólica) a mais abundante. Como a atividade dessa enzima encontra-se fortemente correlacionada com a concentração sanguínea de Se, este parâmetro é normalmente utilizado como indicador do balanço metabólico do mineral. A concentração de Se nos alimentos depende do local onde foram cultivados e r

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Soares, Margarete de Sá. "Avaliação nutricional relativa ao selênio de indivíduos adultos da cidade de Manaus-Amazonas." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/89/89131/tde-04072018-163514/.

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O selênio (Se) é um mineral essencial para o corpo humano, com ação no sistema imunológico, na glândula tireoide, dentre outras funções. É um nutriente importante na proteção das células contra os efeitos dos radicais livres, já que faz parte da enzima glutationa peroxidase (GPX). O consumo alimentar de Se é dependente da concentração desse elemento nos alimentos que varia em função da concentração do mesmo nos solos. Deste modo, este estudo teve como objetivo geral avaliar o estado nutricional relativo ao selênio de indivíduos adultos da cidade de Manaus-AM, por ser considerada região com sol

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11

Almondes, Kaluce Gonçalves de Sousa. "Influência dos polimorfismos Pro198Leu, -602A/G e Arg5Pro na atividade da enzima glutationa peroxidase e no estado nutricional de indivíduos adultos com relação ao selênio." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-26082015-164222/.

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O objetivo deste estudo foi avaliar o estado nutricional relativo ao selênio em indivíduos adultos relacionando-o com polimorfismos no gene da enzima GPx e sua influência sobre a enzima e o balanço redox. Foram selecionados 343 estudantes da Universidade Federal do Piauí entre 20 e 50 anos, de ambos os sexos, selecionados de acordo com critérios de inclusão adotados, como ausência de doenças crônicas não transmissíveis (DCNT) dentre outros. Sangue venoso foi coletado para análise de Se, genotipagem dos SNP da GPx1 (Pro198Leu, -602A/G e Arg5Pro), da atividade das enzimas antioxidantes (GSH-Px e

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12

Müller, Mike-Freya. "Die Glutathionperoxidase 2 : physiologische Funktion und Rolle in der Azoxymethan-induzierten Colonkanzerogenese." Phd thesis, Universität Potsdam, 2013. http://opus.kobv.de/ubp/volltexte/2013/6695/.

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Das Selenoprotein Glutathionperoxidase 2 (GPx2) ist ein epithelzellspezifisches, Hydroperoxide-reduzierendes Enzym, welches im Darmepithel, vor allem in den proliferierenden Zellen des Kryptengrundes, exprimiert wird. Die Aufrechterhaltung der GPx2-Expression im Kryptengrund auch bei subadäquatem Selenstatus könnte darauf hinweisen, dass sie hier besonders wichtige Funktionen wahrnimmt. Tatsächlich weisen GPx2 knockout (KO)-Mäuse eine erhöhte Apoptoserate im Kryptengrund auf. Ein Ziel dieser Arbeit war es deshalb, die physiologische Funktion der GPx2 näher zu untersuchen. In Kryptengrundepith

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13

Prestes, Alessandro de Souza. "Avaliação do potencial antioxidante de beta-selenoaminas." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/11210.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The antioxidant properties of selenium organic compounds have been largely investigated in the last decades, especially because the oxidative stress is directly related to various chronic-degenerative deseases. However, a few studies verify the action of nucleophlilic or electrophilic radicals on the protective activity of selenium compounds. In this work, it was evaluated the influence of different substituent radicals on the antioxidant activities of β-selenoamines. The capacity of β-selenoaminas in mimicry the glutathione pero

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14

Johansson, Henrik. "Exploring Novel Catalytic Chalcogenide Antioxidants." Doctoral thesis, Uppsala universitet, Institutionen för biokemi och organisk kemi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-122485.

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This thesis is concerned with the synthesis and evaluation of regenerable chalcogen containing antioxidants. Variously substituted 2,3-dihydrobenzo[b]selenophene-5-ol antioxidants were evaluated in order to gain information about structure/reactivity-relationships. Within the series explored, the most regenerable unsubstituted compound inhibited lipid peroxidation for more than 320 minutes when assayed in a two-phase lipid peroxidation model in the presence of N-acetylcysteine (NAC). α-Tocopherol which could inhibit lipid peroxidation for 90 minutes under similar conditions was therefore easil

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15

Švedaitė, Vita. "Seleno turinčių ir antioksidaciniu veikimu pasižyminčių priedų įtaka penimų kiaulių produkcijos kokybei ir sveikatingumui." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2007. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2007~D_20071129_145639-44497.

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Nustatyti vitamininių – mineralinių priedų – „Sel-PlexTM“, „Suplex E-50000/K/Selenium“, „Suplex E/Selenium“ (savo sudėtyje turinčių seleno) ir „Oxistop“ – pasižyminčių antioksidaciniu veikimu, įtaką, kiaulių hematologiniams, mėsos fiziniams ir cheminiams bei zootechniniams produktyvumo rodikliams. Remdamiesi atliktų bandymų duomenimis, paruoštos kiaulininkystės ūkiams ir ūkininkams rekomendacijos dėl vitamininių – mineralinių priedų, savo sudėtyje turinčių organinio ir neorganinio seleno formų ir pasižyminčių antioksidaciniu veikimu panaudojimo ir šėrimo efektyvumo penimoms kiaulėms. Pirmą kar

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16

Poon, Jia-fei. "Exploring Catalytic Tellurium-Based Antioxidants : Synthesis and Evaluation." Doctoral thesis, Uppsala universitet, Organisk kemi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-302475.

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This thesis is concerned with the synthesis and evaluation of various tellurium-based chain-breaking antioxidants. The purpose is to find novel regenerable compounds with improved radical-trapping capacity. In the first part of this work, we explore the possibilities to incorporate tellurium into tocopherols and aromatic amines. Overall, tocopherols carrying alkyltelluro groups are better radical-trapping agents than the corresponding sulfur- and selenium analogues. Among them, 7-octyltelluro δ-tocopherol showed a ca. 17-fold higher reactivity than recorded for α-tocopherol and much better reg

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17

Cominetti, Cristiane. "Efeitos da suplementação com castanha-do-brasil (Bertholletia excelsa H.B.K.) sobre o estresse oxidativo em mulheres obesas e sua relação com o polimorfismo Pro198Leu no gene da glutationa peroxidase 1." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-31052010-140506/.

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Indivíduos obesos apresentam níveis elevados de estresse oxidativo quando comparados com controles de peso eutrófico. Isto pode ser atribuído a uma série de fatores, com destaque para a ingestão reduzida de substâncias antioxidantes. Outro aspecto a ser considerado é a presença de polimorfismos em genes que codificam para enzimas antioxidantes, como é o caso do Pro198Leu no gene da enzima glutationa peroxidase 1 (GPx 1). Portanto, este trabalho teve como objetivos estudar as relações entre obesidade, marcadores de estresse oxidativo e o polimorfismo Pro198Leu no gene da GPx1, além de verifi

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18

Krehl, Susanne. "Das Selenoprotein Glutathionperoxidase-2 : physiologische Funktion und Einfluss auf die entzündungsassoziierte Colonkarzinogenese." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5022/.

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Bei der Entdeckung der Glutathionperoxidase-2 (GPx2) wurde zunächst davon ausgegangen, dass die Funktion dieses Enzyms im Kryptengrund des Colons einzig in der Reduktion von H2O2 besteht. Im Laufe der weiteren Erforschung zeigte sich, dass GPx2 auch in verschiedenen Tumorgeweben vermehrt exprimiert wird. Dabei wird diskutiert, ob die Wirkung von GPx2 im Tumor eher als pro- oder als antikarzinogen einzustufen ist. Mehrere Experimente in vitro und in vivo zeigten antiinflammatorische Eigenschaften der GPx2. Aufgrund dieser Befunde wird derzeit über weitere Funktionen der GPx2 spekuliert. In dies

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19

Tanguy, Stéphane. "Etude de l'implication des espèces réactives dérivées de l'oxygène dans les manifestations du syndrome de reperfusion du myocarde ischémique au cours du vieillissement : effet d'une supplémentation alimentaire en sélénium." Université Joseph Fourier (Grenoble), 1999. http://www.theses.fr/1999GRE10025.

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Ce travail constitue une contribution originale a l'etude de l'implication des especes reactives derivees de l'oxygene (erdo) dans les manifestations du syndrome de reperfusion post-ischemique du cur isole perfuse de rat au cours du vieillissement. Dans la premiere partie, nous avons mis en evidence une limitation significative des arythmies de la reperfusion sous l'effet de diverses interventions modulant le stress oxydatif induit par la reperfusion. Cette limitation a pu etre obtenue aussi bien en utilisant une molecule pharmacologique originale presentant des proprietes antiradicalaires cat

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20

Pires, Liliane Viana. "Avaliação do estado nutricional relativo ao zinco e ao selênio de pacientes com síndrome de Turner em diferentes fases de desenvolvimento." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-09012015-160943/.

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Estudos relacionando a síndrome de Turner com o estado nutricional relativo aos micronutrientes, em especial o zinco e selênio, são praticamente inexistentes. Portanto, o presente estudo teve como objetivo avaliar o estado nutricional relativo ao zinco e ao selênio dessa população, considerando as diferentes fases de vida. A avaliação antropométrica das crianças mostrou que 55,6% estavam eutróficas e 44,4% com sobrepeso, de acordo com o índice de peso/estatura. As adolescentes foram classificadas segundo o percentil de IMC ajustado para a idade, onde 73,7% estavam eutróficas e 26,3% com sobrep

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Cardozo, Leila. "Perfil de ácidos graxos, estabilidade oxidativa e aspectos sensoriais do leite de vacas suplementadas com óleo de linhaça na dieta e selenito de sódio injetável." Universidade Federal de Santa Maria, 2011. http://repositorio.ufsm.br/handle/1/10085.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The objective of the present work was to evaluate the effect of dietary linseed oil with or without injection of sodium selenite upon fatty acid profile and oxidative stability of milk from dairy cows as well as the acceptance of the milk and the increasing order of preference by the evaluators. Chapter 1 describes the experiment where fourteen cows were allocated into four treatments: Group 1 which received daily 400 mL of linseed oil (LIN); Group 2, 400 mL of linseed oil + 0.2 mg/BW sodium selenite IM (LINSe); Group 3, untreated

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22

Nishimura, Luciana Sigueta. "Polimorfismo PRO198LEU no gene para a enzima antioxidante dependente de selênio glutationa peroxidase 1 e risco de câncer epidermóide da cavidade oral e orofaringe." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/89/89131/tde-31012011-102550/.

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O selênio é um micronutriente essencial que apresenta ação antioxidante por meio de selenoproteínas, como a glutationa peroxidase 1 (GPX1). O polimorfismo PRO198LEU no gene em questão tem sido relacionado ao aumento do risco para alguns tipos de câncer, como o de mama e pulmão. Atualmente, o câncer de cabeça e pescoço é um importante problema de saúde pública no mundo e, inclusive, no Brasil. O objetivo do presente estudo foi avaliar eventual associação entre o polimorfismo GPX1 PRO198LEU e risco de câncer epidermóide da cavidade oral e orofaringe, bem como possível interação com utilização de

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23

Fischer, Sandra. "Effekte einer Selen- und Vitamin E-Supplementierung auf den peripartalen antioxidativen Stoffwechsel und die Morbidität bei Milchkühen." Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-166660.

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Zielstellung dieser Studie war es zu überprüfen, ob durch Fütterung einer mit Vitamin E und Selen angereicherten Mineralstoffmischung in der Transitphase eine Beeinflussung des antioxidativen Status mit Reaktionen GPX [Glutathionperoxidase], SOD [Superoxiddismutase], TEAC [Trolox equivalent antioxidative capacity] und ACW [nichtenzymatische wasserlösliche Antioxidantien] sowie des Stoffwechsels erreicht werden kann und ob damit die Häufigkeit der in der Frühlaktation typischen Erkrankungen sinkt. Zur Beantwortung dieser Fragestellung wurden in einem Milchviehbestand mit 1400 Kühen und Färsen z

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Banning, Antje. "Selenabhängige Glutathionperoxidasen als Mediatoren und Ziele der intrazellulären Redoxregulation : Identifizierung der GI-GPx als Ziel für Nrf2 und der PHGPx." Phd thesis, Universität Potsdam, 2005. http://opus.kobv.de/ubp/volltexte/2005/543/.

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Das 1817 erstmals schriftlich erwähnte Selen galt lange Zeit nur als toxisch und sogar als procancerogen, bis es 1957 von Schwarz und Foltz als essentielles Spurenelement erkannt wurde, dessen biologische Funktionen in Säugern durch Selenoproteine vermittelt werden. Die Familie der Glutathionperoxidasen nimmt hierbei eine wichtige Stellung ein. Für diese sind konkrete Funktionen und die dazugehörigen molekularen Mechanismen, welche über die von ihnen katalysierte Hydroperoxidreduktion und damit verbundene antioxidative Kapazität hinausgehen, bislang nur unzureichend beschrieben worden. <br><br

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Wilke, Berenice Cunha. "Carence en sélénium et ses conséquences chez l'enfant phénylcétonurique et dans la mucoviscidose." Nancy 1, 1989. http://www.theses.fr/1989NAN10374.

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La carence en SE et ses conséquences sur l'activité de la glutathion-péroxydase et sur deux marqueurs de la péroxydation lipidique ont été étudiés dans deux groupes d'enfants : les phénylcétonuriques recevant un apport journalier insuffisant en SE ; les enfants atteints de mucoviscidose qui malgré un apport normal en SE, présentent aussi une carence en SE par défaut d'absorption. Après la mise en évidence de cette carence nous avons étudié l'effet sur tous ces paramètres, d'une supplémentation en SE. Pendant 18 mois chez les PCU et dans la mucoviscidose, au cours d'une supplémentation en lipid

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Karren, Brady. "THE EFFECT OF ORGANIC SELENIUM SUPPLEMENTATION AND DIETARY ENERGY MANIPULATION ON MARES AND THEIR FOALS: SELENIUM CONCENTRATIONS, GLUTATHIONE PEROXIDASE ACTIVITY, FOALING PARAMETERS AND FOAL PHYSICAL CHARACTERISTICS." 2008. http://hdl.handle.net/1969.1/ETD-TAMU-2008-08-54.

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Quarter Horse mares (n=28, 465-612 kg BW, 6-19 yrs of age) were used to investigate the effect of organic selenium (Se) supplementation (Selenosource, Diamond V Mills, Inc. Cedar Rapids, IA (SeM)) and DE manipulation on plasma, muscle, and colostrum Se concentrations, plasma glutathione peroxidase (Gsh-Px) activity, foaling parameters, and physical characteristics in mares and their foals. Mares were arranged in a 2x2 factorial with two levels of nutrition, pasture (100% NRC DE) or pasture plus grain (120% NRC DE) (fed at 0.75% BW (0.63 ppm Se)) and two levels of Se supplementation (0 or 0.3 m

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Lin, Yung Kang, and 林雲康. "Effects of Selenium Priming Treatments on Glutathione Peroxidase Activity of Bitter Gourd Seeds." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/31923438600255043306.

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碩士<br>國立中興大學<br>農藝學系<br>90<br>Selenium is a constitute of glutathione peroxidase (GPX). It is kown that priming the seeds with selenium solution enhances the activity of seed’s GPX. In the study, bitter gourd seeds (cv. Moon Shine) were primed with water or 5 ppm selenium solution, the activities of GPX and antioxidants were determined during hydration and redrying period. The results indicated that the embryo axis GPX activity was enhanced by selenium priming. Additionally selenium priming was increase the glutathione contents of treated seeds. For further examing the effect of selenium on t

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LING, KE TSAI, and 柯采伶. "The effects of different selenium compounds supplementation on glutathione peroxidase and monoamine oxidase in cell models." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/38875334113522115657.

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碩士<br>中華醫事學院<br>生物科技研究所<br>95<br>Selenium (Se) is the important composition of glutathione peroxidase (GPX). Therefore, selenium perform in the role of antioxidation function. The enzyme monoamine oxidase (MAO-B) plays an important role on aging-related diseases, such as Parkinson’s and Alzheimer’s diseases. Because of the observation that MAO-B activity is increased during ageing, it is regarded as the index of ageing. The purpose of this study was to understand the effects of organic / inorganic selenium supplements on GPX enzyme activity, GPX protein expression, and MAO enzyme activity. Fir

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"Selenium Supplementation and Cardiovascular Outcome Markers in Hemodialysis Patients: A Randomized, Controlled Trial." Doctoral diss., 2013. http://hdl.handle.net/2286/R.I.17975.

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abstract: Background Hemodialysis (HD) patients elicit an oxidant-antioxidant imbalance in addition to a selenium deficiency, possibly contributing to cardiovascular disease (CVD) mortality. Objective To evaluate the effect of selenium supplementation on CVD outcomes and antioxidant status in HD patients. Design A randomized controlled intervention trial conducted from October 2012 to January 2013. Participants/setting The study included 27 maintenance HD patients (61.1+17.5y, 14M, 13F) receiving HD in the greater Phoenix, AZ area. Intervention Patients received one of three treatments daily:

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Bhabak, Krishna Pada. "Synthetic Antioxidants : Structure-Activity Correlation Studies Of Glutathione Peroxidase Mimics And Peroxynitrite Scavengers." Thesis, 2009. http://hdl.handle.net/2005/996.

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Reactive oxygen species (ROS) such as superoxide radical anion (O2•¯), hydroxylradical (OH•), hydrogen peroxide (H2O2) and peroxynitrite (ONOO-) that are produced during the metabolism of oxygen under oxidative stress in aerobic organisms destroy several key biomolecules and lead to a number of disease states. Mammalian systems possess several effective defense mechanisms including antioxidant enzymes to detoxify these ROS. The selenocysteine-containing Glutathione peroxidase (GPx) is particularly an efficient enzyme in the detoxification of H2O2 and other hydroperoxides by using glutathione (

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Sarma, Bani Kanta. "Antioxidant Activity Of The Anti-Inflammatory Compound Ebselen And Its Analogues : Role Of Nonbonded Interactions." Thesis, 2008. http://hdl.handle.net/2005/900.

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Although considered as a poison for long time, the importance of selenium as an essential trace element is now well recognized. In proteins, the redox active selenium moiety is incorportated as selenocysteine (Sec), the 21st amino acid. In mammals, selenium exerts its redox activities through several selenocysteine-containing enzymes, which include glutathione peroxidase (GPx), iodothyronine deiodinase (ID) and thioredoxin reductase (TrxR). Although these enzymes have Sec in their active sites, they catalyze completely different reactions and their substrate specificity and cofactor or co-subs

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Fischer, Sandra. "Effekte einer Selen- und Vitamin E-Supplementierung auf den peripartalen antioxidativen Stoffwechsel und die Morbidität bei Milchkühen." Doctoral thesis, 2014. https://ul.qucosa.de/id/qucosa%3A13288.

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Zielstellung dieser Studie war es zu überprüfen, ob durch Fütterung einer mit Vitamin E und Selen angereicherten Mineralstoffmischung in der Transitphase eine Beeinflussung des antioxidativen Status mit Reaktionen GPX [Glutathionperoxidase], SOD [Superoxiddismutase], TEAC [Trolox equivalent antioxidative capacity] und ACW [nichtenzymatische wasserlösliche Antioxidantien] sowie des Stoffwechsels erreicht werden kann und ob damit die Häufigkeit der in der Frühlaktation typischen Erkrankungen sinkt. Zur Beantwortung dieser Fragestellung wurden in einem Milchviehbestand mit 1400 Kühen und Färsen z

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