Dissertations / Theses on the topic 'Horse5'

This dissertation examines the cultural and historical dimensions of why certain communities in the United States are compelled to rescue animals from abuse, neglect, or death. In particular, it engages with the debate over sending “unwanted” horses to slaughter, touching upon not just the history of cultural taboo over the consumption of horsemeat and concerns about the cruelty and food safety of industrialized animal slaughter, but also what happens to such horses when they are rescued from slaughter. As such, this dissertation fundamentally asks: what makes a horse save-able and re-wanted again? What kind of lives do they go on to live and why? And how are the decisions to “rescue” certain horses and provide them with “second chances” distinctly cultural and worthy of anthropological analysis? Based on the emerging field of multispecies ethnography, this dissertation thus examines how and why a certain population of the so-called unwanted horses, Thoroughbred ex-racehorses, are rescued from slaughter and how this practice is made culturally meaningful by the “horse people” in the self-proclaimed “horse capital of world,” the Lexington / Bluegrass region of Kentucky, U.S.A. My analysis stems from ten months of fieldwork in the Bluegrass where I conducted ethnographic research at two specific rescue operations for Thoroughbred ex-racehorses: one an equine re-training and adoption facility based at the Kentucky Horse Park called the Maker’s Mark Secretariat Center, and the other a vocational horse care program for male inmates at Blackburn Correctional Complex called the Second Chances / Groom Elite program. Based on my research at these two sites as they are situated within a larger, regional culture intently focused on the production and glorification of horses, this dissertation concludes that the practice of animal rescue involves constant re-evaluation of the moral and economic worth of human and nonhuman animal lives that were previously marginalized to the point of social and/or mortal death, a concept I have termed “redemptive capital.” Redemptive capital helps measure “who” gets saved and why - and furthermore, how once a life is spared death, what implicit debt is owed one’s redeemers.
Arts, Faculty of
Anthropology, Department of
Graduate

Thesis (M. Sc. Vet. Sc.)--University of Sydney, 2008.
Includes graphs and tables. Title from title screen (viewed June 11, 2009) Submitted in fulfilment of the requirements for the degree of Master of Science in Veterinary Science to the Faculty of Veterinary Science. Degree awarded 2008; thesis submitted 2007. Includes bibliography. Also available in print form.

African horse sickness (AHS) is a life threatening disease of equids caused by African horse sickness virus (AHSV), a member of the genus Orbivirus in the family Reoviridae. The virus is transmitted to horses by midges (Culicoides spp.) and the disease is most prevalent during the time of year, and in areas where the Culicoides spp. are most abundant, namely in late summer in the summer rainfall areas of the country. Whilst the clinical signs and presentation of the disease were well documented by Sir Arnold Theiler (1921), very little is known or documented about AHSV dynamics or the clinical pathological and serological responses of horses to natural infection with AHSV. This dissertation describes the history and current knowledge on AHS, and the methods and results of a prospective study on natural AHSV infection of horses, undertaken between 2009 and 2010 by the Equine Research Centre (ERC) at the University of Pretoria, Faculty of Veterinary Science, Onderstepoort. This study is the first documented study of its nature and included animals of various ages and therefore variable vaccination status. The objectives of the study were to describe the viral dynamics of AHSV infection in horses, to gain a better understanding of the clinical pathological and serological responses to natural AHS infection and to demonstrate early detection of AHS infection in horses under field conditions.
Dissertation (MSc)--University of Pretoria, 2010.
Veterinary Tropical Diseases
unrestricted

The purpose of this study was to evaluate active stable systems, and their improvement of the horses on animal welfare and the horses’, natural behavior. The evaluation was made through interviews with the managers of two active stables in Piteå, Sweden and practical studies of the horses’ behavior at those two active stables and also one traditional stable. The results showed that the horse’s circadian rhythm differed between the various groups. The horses that were kept in the active stable systems rested and foraged spread over day and night while horses kept in the traditional stable mainly rested at night and ate during the day. The horses get better outlet for their natural behavior in the active stable system because the need of movement and socializing were met around the clock. Keeping horses in the active stable system, however, is associated with a risk of injury because of the competitive situations that occur around the feeding stations, and trauma injuries have occurred in both active stables in this study.

Osteoarthritis of the metacarpo/metatarsophalangeal joint is a major cause of lameness in the horse. Magnetic resonance imaging and particularly delayed gadolinium enhanced imaging of cartilage (dGEMRIC) and T2 cartilage mapping in humans has been shown to visualize cartilage matrix changes in osteoarthritis early in the disease process. T2 mapping is a non-invasive technique characterizing hyaline articular cartilage and repair tissue. In dGEMRIC, the negatively charged administered Gd-DTPA2−, penetrates hyaline cartilage in an inverse relationship to the proteoglycan concentration thereof. In osteoarthritis, proteoglycan concentration is decreased with increased penetration of Gd-DTPA2− due to a relative decrease in negative charge of the proteoglycan-depleted cartilage. This study was performed on normal cadaver limbs of twelve euthanized racing Thoroughbreds. Six horses’ midcondylar distal third metacarpals/metatarsals (Mc3s/Mt3s) underwent six precontrast inversion recovery (IR) sequences for dGEMRIC T1 relaxation time calculation, as well as T2 mapping sequences using a 1.5T machine. Gd-DTPA2- was injected intra-articularly and the same six IR sequences repeated at 30, 60, 120, and 180 minutes post-injection at the same midcondylar sites. The distal Mc3/Mt3 cartilage thickness was measured histologically and compared to selected images of the T1 and T2 weighted sequences. T1 and T2 maps were created by fitting the respective data into mono-exponential relaxation equations for each pixel, and mean values of certain regions of interest were calculated. A second group of six horses’ fore and hind limbs were randomly assigned to two groups and the limbs either chilled or frozen, allowed to return to room temperature and scanned similarly to the first control group. Chilling and freezing effects on dGEMRIC and T2 mapping results were evaluated. The main conclusions from this study are that IR and proton density weighted (T2 mapping) sequences can measure distal Mc3/Mt3 cartilage thickness where the cartilage doesn’t overlap with that of the proximal phalanx. However, accurate measurement was hampered by the thin cartilage in this region. dGEMRIC mapping, using intra-articular Gd-DTPA2- is a feasible technique and T1 relaxation times decrease in a similar fashion to that of the human, with the optimal time of scanning after intra-articular Gd-DTPA2- injection being 60-120 minutes. There is little effect on T1 or T2 relaxation time and mapping images after chilling and freezing of the limbs except where the magic angle effect predominates in the T2 mapping sequences. Limitations of this study include relatively coarse spatial resolution of the thin cartilage, the overlap of the distal Mc3/Mt3 cartilage with the adjacent phalanx and the relatively low number of limbs used, resulting in low statistical power, particularly in the frozen limbs’ study. In spite of these limitations, this study provides technical information and reference values of dGEMRIC and T2 mapping in the cadaver distal Mc3/Mt3 of the normal Thoroughbred horse of value for forthcoming studies. Future studies need to evaluate intravenous administration of Gd-DTPA2- and cartilage mapping in live exercised vs. non-exercised horses. Ultimately, dGEMRIC and T2 mapping of horse metacarpo/metatarso-phalangeal joints with differing degrees of osteoarthritis should be used to attempt to diagnose early cartilage degeneration to endeavour to halt or delay its progression.
Thesis (PhD)--University of Pretoria, 2013.
gm2013
Companion Animal Clinical Studies
unrestricted

The purpose of this study was to develop an effective method for trailer loading horses based on the principles of positive reinforcement. Target training and shaping were used to teach trailer loading behavior in a natural setting. Five AQHA mares were selected for this program. All five had been loaded before through the use of punishment. A two-horse trailer was used. Approximations to loading and inappropriate behaviors were the dependent variables. When intervention started the target was moved to various locations inside the trailer. Subjects started training on the left side of the trailer. After a subject was loading in the left side they were moved to the right side, then to loading half on the right and half on the left, then they were loaded by a different trainer, and into a different trailer. For one subject a limited hold was utilized, as well as a companion horse.

Observed and expected heterozygosity (H) levels for ten electrophoretic blood marker loci and expected H for seven red blood cell (RBC) anitgen/antibody loci were examined for 20 years in American Standardbred and 30 years in American Saddlebred horses. Standardbreds were classed by gait, Trotter and Pacer, and evaluated separately in most analyses. 4,404 Trotters and 12,271 Pacers were found to have statistically highly significant losses of mean total observed H through time for the ten electrophoretic loci (P<0.005), although in Trotters the loss was more extreme (P<<0.001). Loss of H in 5984 Saddlebreds was not significant (P=0.259). Correlations of RBC expected H through time showed decreases in all three groups.

Although equine charities’ presence in developing countries is assumed to improve working equine health, little scientifically substantiated information is available on the impact of such projects in targeted communities or about communities’ horse health priorities. This work aims to (i) evaluate and quantify the impact of World Horse Welfare training in farriery, saddlery and nutrition-related interventions on health of Lesotho’s working horses (ii) elicit community priority horse health topics using participatory methods for comparison with topics identified using epidemiological techniques. A baseline cross-sectional survey was conducted before World Horse Welfare’s first training course, with two follow-up surveys 9 and 20 months after first year course completion. Each followed a standardised clinical examination protocol for horses and administered a structured questionnaire on equine husbandry/primary health care knowledge and practices with study horses’ owners. Standardised data on tack used on horses was also collected. Data was analysed quantitatively to assess changes in equine health and tack parameters and owners’ knowledge and practices over the intervening period. Following impact evaluation, owner discussion groups were convened, employing participatory facilitation techniques to elicit owner-specified key horse health-associated issues and their priority order. Limited changes in farriery-related parameters were identified, but few saddlery-related improvements resulted; problems including high prevalence of poor tack and tack-associated injuries persisted. High prevalence of suboptimal body condition score, sharp enamel teeth points, parasite infestation, overgrown hooves and adverse clinical pathology parameters persisted throughout the study. Owners’ basic husbandry knowledge and application remained variable. Community-specified horse health priorities were mouthcare, nutrition, disease management, feet and husbandry. Engaging horse owners to understand country-specific issues and elicit community priorities is essential before designing interventions to improve equine health. A complex change process involving owner knowledge, attitudes and behaviour, underpinned by community support and bespoke step-wise interventions is required to achieve sustainable equine health improvements.

A radiographic examination forms part of the pre-purchase examination of Thoroughbred yearlings at national sales in many countries. This data enables the recording of the prevalence of radiographic changes in selected Thoroughbred populations around the world and assists veterinarians in advising clients on the purchase of yearlings. This has financial implications for the client as well as the racing industry as a whole. Radiographic examinations of the 269 Thoroughbred yearlings lodged at the 2008 National Yearling Sale in Germiston, South Africa were collected and individually evaluated. The prevalence of radiographic changes was recorded and percentages calculated. These changes were compared to studies of other yearling populations. Radiographic changes present in the studied Thoroughbred population are: pedal osteitis 1.26%, metatarsophalangeal joint dorsal osteochondral fragmentation 1.60%, sagittal ridge changes 5.7%, ulnar carpal bone lucencies 8.33%, carpal osteophytes 1.19%, distal intertarsal and tarsometatarsal joint radiographic changes 9.92%, tarsal osteochondrosis lesions 4.4% and stifle joint osteochondrosis lesions 0.4%. These changes were found to be of lower prevalence when compared to similar studies. The prevalence of dorsal osteochondral fragments in the metacarpophalangeal joint was 1.60% which was similar to other studies. A higher prevalence of vascular channels was visible in the proximal sesamoid bones as well as irregular borders and lucencies. Palmar metacarpophalangeal and plantar metatarsophalangeal osteochondral fragments had a recorded prevalence of 2% and 7.10%, respectively, this prevalence being generally higher when compared to similar studies. There was an absence of palmar metacarpal disease, supracondylar lysis, proximal sesamoid bone fractures and carpal osteochondral fragmentation in the current study. Additional findings recorded in the current study were: proximal interphalangeal joint hyperextension (left front 15.13%, right front 18.91%), the solar angle (right front 2.38°, left front 2.79°), the prevalence of carpal bone one (30.95%) and carpal bone five (1.59%). The study population was limited to the radiographs lodged at the sale repository. As radiographic changes may influence sale price of the yearling, radiographs of yearlings with severe radiographic changes may not have been lodged at the repository. For these reasons the prevalence of radiographic changes recorded in the current study may not be a true reflection of the entire 2006 Thoroughbred foal crop. Further work to correlate radiographic changes to differences in management, pre-sale exercise programmes and genetics needs to be done. The effect of radiographic changes on the future performance of the Thoroughbred yearling also warrants further investigation. Copyright
Dissertation (MSc)--University of Pretoria, 2009.
Companion Animal Clinical Studies
unrestricted

African horse sickness is an infectious, insect-borne but non-contagious disease of equids responsible for more than 95% mortality in naïve horses. The African horse sickness virus has ten segments of double stranded RNA encoding seven structural and three non-structural proteins. There is currently no cure for the disease and one of the effective ways to control or prevent new infection is by vaccination. Although successful, the currently used vaccine is not registered for use outside the sub- Saharan region because of fears of reversal to virulence. Inactivated and subunit vaccines have been tested but are not commercially available. Research towards recombinant vaccines that will offer protection without these limitations is thus ongoing. Identification and characterisation of antigenic regions on proteins has always been essential in the development of vaccines and immunodiagnostic reagents. AHSV proteins have been shown to confer protection to model animals in one form or another. This study was undertaken to investigate the global humoral immune reaction during immunisation in horses. This was done using sera from immunised horses and a genome-targeted phage display library. A phage library expressing a repertoire of AHSV-4 peptides large enough to represent the whole genome was constructed. The library was affinity selected with purified naïve (day 0) and immunised (day 28, day 52) horse IgGs and a pool of phages expressing binding peptides were isolated. The DNA inserts of the pool of phages were subjected to high throughput sequencing and sequences identified by matching them to the AHSV-4 genome. Analysis of the extensive data output selected by the naive and immunised IgGs enabled a thorough examination of the panning process. Sequences were normalised by subtracting the naïve from the immunised sequences. Comparing the sequences selected with day 28 IgG enabled identification of 16 potentially antigenic regions recognised by most horses. Some of these regions could easily have been missed with the traditional clone picking approach. Some of the regions were also selected by most horses with day 52 IgG, indicating persistent antibodies. Potentially antigenic regions were identified without the functional re-testing which is common part of traditional phage display. This was due to lack of access to the single clones in the library. One way to confirm binding of selected regions is by peptide ELISA, which was started in this study. This study improved on all the phage display work already done on orbiviruses and offered more information on the immunogenicity of AHSV-4 in horses. Future work should focus on confirming antigenicity of the selected regions. The potential antigenic regions could be fused with T-cell epitopes, identified in a parallel study, to form a construct that might induce production of humoral and cellular immune responses.
Dissertation (MSc)--University of Pretoria, 2015.
tm2016
Veterinary Tropical Diseases
MSc

Dissertação de Mestrado Integrado em Medicina Veterinária
Equus ferus przewalskii, currently assumed as subspecies of E. ferus, is considered as endangered by the International Union for Conservation of Nature (IUCN). The ex situ conservation has been crucial for the continued preservation of this subspecies, once considered extinct in the wild. The Pentezug Wildhorse Reserve, located in the Hortobágy National Park, in Hungary, has one of the biggest ex situ populations of Przewalski’s horses and it’s aimed to preserve its typical landscape and to study wild horses in a semi-wild habitat, making part of this subspecies reintroduction plan. Currently, this population comprises almost 280 Przewalski's horses, sharing the area with a population of domestic cattle (Bos primigenius taurus), carefully bred to reconstructed aurochs (Bos primigenius). In this study, 79 faecal samples were collected and the coprological methods (McMaster, Willis floatation, natural sedimentation, Baermann and coproculture) and corresponding microscopic identification were performed in all the samples. Results show an average level of 1286.7 Eggs per Gram (EPG), which is considered a high level of parasitism. All the 79 samples analysed were positive for strongylid-type eggs (100% prevalence) (79/79), with a dominance of the cyasthostominae, when compared to strongylinae and tricostrongylidae. Moreover, a total of 15 different morphological L3 types and/or species identified of the order Strongylida. Additionally, 27.8% (22/79) were positive to Parascaris sp. and 2.5% (2/79) contained Oxyuris equi in their expelled faeces. By the sedimentation method, we could only evidence a Trematoda egg (1/79). In the subfamily Cyathostominae, L3 of cyathostomins type A showed 100% prevalence. In Strongilinae, Strongylus vulgaris is the most prevalent (40.5%), followed by Triodontophorus serratus (12.7%). These results are consistent with the other studies performed in the same subspecies and represent the first survey of gastrointestinal parasites performed with this level of detail in this population of Przewalski’s horses. Statistically, this study revealed that animals infected by Parascaris spp. tend to be positive in association with cyathostomins type C. In the same way, animals infected by T.serratus tend to be positive for Poteriostomum spp., possibly due to the propensity of juveniles for these two parasites revealed in this study. Furthermore, males have more S. vulgaris infections than females and animals infected by S. vulgaris tend to have lower levels of EPG. These results reveal the importance of parasite monitoring in wild ex situ populations, especially those that can be part of a reintroduction program, to better-knowing their pathogenic potential, possible parasite associations, predisposition factors and consequences for the subspecies conservation.
RESUMO - Parasitas gastrointestinais em cavalos de Przewalski (Equus ferus przewalskii), na reserva de cavalo selvagem do Pentezug, Parque Nacional de Hortobágy, Hungria - Equus ferus przewaslkii é classificada como uma subespécie de E. ferus. Presentemente, encontra-se em perigo, segundo a União Internacional para a Conservação da Natureza (IUCN), apesar de já ter assumido o estatuto de Extinta na Natureza. Por este motivo, a conservação ex situ tem tido um papel crucial na conservação desta subespécie. A reserva de cavalo selvagem do Pentezug, inserida no parque nacional de Hortobágy, na Hungria, tem uma das maiores populações ex situ de cavalo de Przewalski, com os principais propósitos de conservar a paisagem característica da região e aprofundar os conhecimentos sobre a subespécie, fazendo parte do seu programa de reintrodução. Atualmente, esta população é composta por cerca de 280 cavalos de Przewalski, que partilham a pastagem com uma população de bovinos domésticos (Bos primigenius taurus), selecionada de forma a apresentar um fenótipo semelhante ao auroque (Bos primigenius). Foram colhidas 79 amostras fecais e os métodos coprológicos (McMaster, flutuação de Willis, sedimentação natural, Baermann e coprocultura) e a respetiva identificação microscópica foram executados para todas as amostras. Os resultados demonstraram um nível de parasitismo médio de 1286,7 ovos por grama (OPG), o que representa um valor elevado. Todas as amostras foram positivas para ovos do tipo estrongilídeo (100% de prevalência) (79/79), com uma dominância dos ciatosmíneos, comparando com estrongílideos e tricostrongilídeos, e revelaram uma diversidade de 15 espécies ou morfotipos de L3 dentro da ordem Strongylida. Adicionalmente, 27,8% (22/79) foram positivas para Parascaris sp., 2,5% (2/79) dos animais continham Oxyuris equi nas fezes expelidas e numa amostra foi detetado um ovo de trematode (1/79). As L3 de ciatostomíneos de tipo A revelaram uma prevalência de 100%. Na subfamília Strongilinae, Strongylus vulgaris foi o mais prevalente (40.5%), seguido de Triodontophorus serratus (12,7%). Estes resultados são consistentes com outros estudos efetuados na espécie e representam o 1º estudo parasitológico na população de Pentezug, realizado com este nível de detalhe. Estatisticamente, este estudo revelou que animais positivos a Parascaris spp. tendem a ser positivos para ciatostomíneos do tipo C. O mesmo acontece entre T. serratus e Poteriostomum spp., possivelmente devido à predisposição dos juvenis para estes dois parasitas revelada neste estudo. Do mesmo modo, os machos têm mais infeções por S. vulgaris do que as fêmeas e os animais positivos para este parasita tendem a ter níveis mais baixos de OPG. Estes resultados demonstram a importância da monitorização parasitológica em populações ex situ, especialmente as que fazem parte de um programa de reintrodução, com o objetivo de aprofundar o conhecimento sobre o poder patogénico dos agentes, possíveis coinfeções, fatores de risco e consequências para a conservação da subespécie.
N/A

Dissertation (PhD(Agric))--University of Stellenbosch, 2004.
ENGLISH ABSTRACT: This study was carried out to investigate whether environmental and/or genetic factors had an effect on the incidence of epistaxis related to exercise-induced pulmonary haemorrhage among racehorses in Southern Africa. A further aim was to estimate the heritability of liability to epistaxis in the Southern African Thoroughbred population. For the purpose of the environmental study, the data covering the period 1986-2001 and involving a total of778 532-race runs, were analysed. This included the following race start information: date of race (day/month/year), age, sex, breeder, trainer, distance, jockey, state of going, weight carried, centre of racing and altitude. The genetic part of the data was two-fold in nature and included firstly the analysis of all horses that suffered epistaxis whilst racing in Southern Africa from 1986 to 2001 and involving 1118 individual bleeders. The second genetic analysis included the same Southern African population plus those Southern African horses exported to Mauritius and then being recorded as bleeders in that country (1252 bleeders in total). Pedigree data covering the period 1960-1986 was used as required to calculate the incidence of bleeding amongst ancestors of the post 1986 era. Only pedigrees of horses that raced were included in this study as it was not possible to predict whether non-runners would have bled had they raced. Consequently all non-runners and also those that raced overseas in countries where bleeding occurrence was not recorded were excluded. Veterinarians employed by the Jockey Club suspended officially recorded horses that showed epistaxis as demonstrated by frank bleeding from the nostrils after racing. Oncourse endoscopy is not employed as a routine on any of the Southern African racetracks. In the environmental study epistaxis was identified in 1 287 race starts (0.165%). Epistaxis related to exercise-induced pulmonary haemorrhage was significantly (p<0.001) associated with altitude, age, race year, month and the day of racing. More horses demonstrated epistaxis at sea level than at altitude, between the months of May - October than the rest of the year, in older horses than in horses less than three-years old, after 1995 than between the years 1986 and 1995, and on Fridays and Sundays than on any other week day. No association could be established between epistaxis and breeder, trainer, distance, jockey, state of going, sex and weight carried. The heritability of liability method as described by Falconer (1989) was used to estimate the relative importance of heredity and environment. For the period investigated, the population incidence for epistaxis in Southern African horses was 2.1%. The estimation of heritability ofliability showed that first-degree relatives had a figure of 55.4%. The heritability of second- and third degree relatives were 41.3% and 30.4% respectively. The data investigated depicts horses that bled almost exclusively on race days as only a small percentage (- 5%) was reported as having bled during exercise. Accordingly, the full extent of epistaxis amongst racing Thoroughbreds in Southern Africa is difficult to gauge. Pedigree and race run data from Thoroughbreds racing in Southern Africa, covering the period 1986-2002 (63 146) horses in pedigree data-set and 778 532 race runs, were further analysed in order to study genetic and environmental factors affecting the incidence of epistaxis as associated with EIPH (exercise-induced pulmonary haemorrhage). As fixed effects for the model, variables that were tested significantly in a preliminary data analyses, were included. Various combinations of such variables namely age, weight, altitude, sex, month and going were tested. Fixed effects that were included in the fmal model were gender, going and altitude. The heritability estimates from a logit transformed analysis for epistaxis fitting both the animal and sire generalized mixed models were 0.23 and 0.40 respectively, which indicated that epistaxis as associated with EIPH in the Southern African Thoroughbred sires has a strong genetic basis. Genetic trends indicating an increase in epistaxis were also found. It is concluded that the frequency of epistaxis related to pulmonary haemorrhage is associated with altitude, winter and spring months and the horse's age. It is suggested that racing at a lower altitude may increase the probability of exercise-induced pulmonary haemorrhage. It is clear that epistaxis in the racing Thoroughbred has a strong genetic basis. It is further suggested that horses showing frank bleeding from the nostrils after racing or exercise, be suspended and not used for breeding purposes. This would result in relatively fast progress being made towards eradicating this costly scourge of the modem Thoroughbred racehorse. Affected stallions and those racing whilst being treated with furosemide, should be barred from breeding and not be considered as future sires. Estimated breeding values for epistaxis should be used as a tool for selecting against it and be considered in breeding programmes to decrease the incidence thereof.
AFRIKAANSE OPSOMMING: 'n GENETIESE ANALISE VAN DIE VOORKOMS VAN LONGBLOEDING IN DIE SUID-AFRIKAANSE RENPERD: Die doel met hierdie studie was om vas te stelof omgewings- of genetiese faktore enige invloed op die voorkoms van longbloeding in die Suid-Afrikaanse renperd het. 'n Verdere doelstelling was om die oorerflikheid op die onderliggende verspreiding van longbloeding in die Suid-Afrikaanse Volbloedpopulasie te bepaal. Vir die omgewingstudie is data wat oor die periode 1986-2001 strek en wat 'n totaal van 778 532 wedren-deelnames ingesluit het, statisties ondersoek. Die data het die volgende inligting ingesluit: datum van deelname, ouderdom, geslag, teler, afrigter, afstand van wedren, jokkie, toestand van baanoppervlakte, gewig gedra, sentrum waar deelname plaasgevind het en die hoogte bo seespieël van die sentrum. Die studie van die genetiese aspekte het eerstens 'n analise van al die perde wat longbloeding tydens 'n wedren in Suider-Afrika gedurende die jare 1986-2002 ondervind het (I118 perde), en tweedens dieselfde populasie perde, plus die Suiderlike-Afrikaanse perde wat uitgevoer is na Mauritius en bloeding daar ondervind het, (1252 perde), ingesluit. Ter aanvulling is uitgebreide stamboomdata van voorouers gedurende 1960-1986 gebruik om die voorkoms van longbloeding tydens die post 1986 tydvak te bepaal. Slegs stambome van renperde wat aktief aan renne deelgeneem het, is in die data ingesluit aangesien dit nie moontlik was om te voorspel of 'n perd wat nooit aan wedrenne deelgeneem het nie, longbloeding sou ondervind indien dit wel deelgeneem het. Dus is alle renperde wat nooit aan wedrenne deelgeneem het, asook daardie perde wat in die buiteland deelgeneem en waar longbloeding nie aangeteken word nie, uitgesluit. Alle perde wat bloeding van die neus na wedrenne getoon het, is deur veeartse in diens van die Jokkie Klub van Suid-Afrika ondersoek, as 'n bloeier aangeteken en van verdere deelname aan wedrenne geskors. Endoskopie word op geen van die Suid- Afrikaanse renbane as 'n standaard praktyk na wedrenne uitgevoer nie. Longbloeding het in 1 287 perde of gedurende 0.165% van alle wedrenne plaasgevind. Longbloeding soos geassossieer met EIPH, (exercise-induced pulmonary haemorrhage), is betekenisvol (p<0.001) met hoogte bo seespieël, ouderdom, dag van deelname, maand, en jaar verbind. Meer perde het longbloeding by seevlak in vergelyking met hoër vlakke bo seespieël ondervind, tussen die maande Mei-Oktober as die res van die jaar, in perde ouer as drie-jaar, na 1995 as tussen die jare 1986-1995, op Vrydae en Sondae as enige ander dag van die week. en meer by reuns as by merries of hingste. Geen verwantskap kon tussen bloeding en teler, afrigter, afstand, jokkie, toestand van baan, geslag en gewig gedra, gevind word nie. Die oorerflikheid op die onderliggende verspreiding vir longbloeding soos omskryf deur Falconer (1989), is gebruik om die relatiewe belangrikheid van oorerflikheid en omgewing te bepaal. Vir die periode bestudeer, was die voorkoms van longbloeding in die Suid-Afrikaanse renperd 2.1%. Die oorerflikheid van longbloeding was 55.4% vir eerste-graadse verwantes. By tweede-graadse verwantes was die ooretlikheid 41.3% en by derde-graadse verwantes 30.4%. Die data wat ondersoek is, was bykans uitsluitlik die van perde wat tydens wedrenne gebloei het en slegs 'n baie klein persentasie (~ 5%) was aangeteken as perde wat tydens oefening gebloei het. Dus is die volle omvang van longbloeding in Suider-Afrikaanse Volbloedperde moeilik om akkuraat te bepaal. Die stamboom- en wedrendata van Suid-Afrikaanse Volbloedperde is verder ontleed in 'n poging om die genetiese en omgewingsfaktore se invloed op die voorkoms van longbloeding, soos geassosieer met EIPH te bepaal. As vaste effekte vir die model is veranderlikes wat betekenisvol gevind was, ingesluit. Verskeie kombinasies van hierdie veranderlikes soos ouderdom, gewig, hoogte bo seespieël, geslag, maand en toestand van die baan is ingesluit. Die vaste effekte wat in die finale model ingesluit is, was geslag, toestand van die baan en hoogte bo seespieël. Die beraamde oorerflikheid verkry vanaf 'n "logit" getransformeerde analise vir longbloeding wat beide die diere- en vader- gemengde model gepas het, was onderskeidelik 0.23 en 0.40, wat 'n aanduidending is dat longbloeding, soos geassosieer met ElPH, 'n sterk genetiese grondslag het. Genetiese tendense het ook gedui op 'n toename in die voorkoms van longbloeding, veraloor die laaste vyf jaar van die studie. Samevattend is die bevinding dat die frekwensie van longbloeding 'n betekenisvolle verwantskap toon met hoogte bo seespieël, winter en lente maande en die perd se ouderdom. Dit word voorgestel dat renperde wat deelneem aan wedrenne by laer vlakke van hoogte bo seespieël, meer onderhewig aan longbloeding sal wees. Uit die resultate verkry is dit duidelik dat longbloeding 'n genetiese grondslag het. Dit word voorgestel dat perde wat fisiese simptome van neusbloeding na of gedurende wedrenne toon, geskors word van verdere deelname en ook nie toegelaat word om mee te teel nie. Hierdie maatreëls behoort aanleiding te gee dat relatief vinnige vordering gemaak sal word in die strewe om hierdie ongewenste sindroom in die moderne Volbloed te verminder. Aangetaste hingste, asook die wat aan wedrenne deelgeneem het terwyl hul behandeling ontvang met furosemide, moet nie toegelaat word om te teel en nie as toekomstige teelhingste oorweeg word nie. Die waarde van voorspelde teelwaardes vir longbloeding moet nie onderskat word in seleksie daarteen nie en moet in teelprogamme om die voorkoms daarvan te verminder, oorweeg word.

Radiographic examination of Thoroughbred racehorses at the time of the yearling sales is common practice in South Africa. Although it is generally accepted that yearlings will have some radiographic changes, there is only one study that estimated the prevalence of these changes in Thoroughbred racehorse yearlings in South Africa. Furniss et al reported on the occurrence of radiographic abnormalities over a one-year period (Furniss 2011). Furniss et al. study differs from other studies in that there was a higher prevalence of palmar metacarpophalangeal and plantar metatarsophalangeal osteochondral fragments and a lower prevalence of pedal osteitis, dorsal osteochondral fragmentation of the metatarsophalangeal joint, distal metacarpal saggital ridge changes, ulnar carpal bone lucencies, carpal osteophytes, distal intertarsal and tarsometatarsal joint changes, tarsal osteochondrosis lesions and stifle osteochondrosis lesions was found. This study will further assist practitioners to identify joints where the most prevalent changes are likely to occur. Our objective was to describe the prevalence and distribution of radiographic changes in the metacarpophalangeal joint, metatarsophalangeal joint, carpi, tarsi, stifle and fore digits of racing Thoroughbred yearlings in South Africa when examined as part of a pre-purchase examination during the Annual National Yearling Sales extending from 2008 through 2010. Thoroughbred racehorse yearlings were subjected to radiographic evaluation including the digit (n= 566 ), metacarpophalangeal joint (n=566 ), metatarsophalangeal joint (n= 566), carpi (n= 566), tarsi (n= 566) and stifle (n=566 ). The radiographic changes were categorised by location and type of change present for each series. The digit Where informal comparisons with previously published data can be made, similar changes of pedal osteitis were recorded in this study, with a total percentage of 6.7%. There was an 8.7% prevalence of inversion of the third pedal bone. Other studies describing radiographic changes in Thoroughbred racehorse yearlings did not investigate inversion of the third pedal bone, therefore results cannot be compared. The metacarpophalangeal and metatarsophalangeal joints with proximal The metacarpophalangeal and metatarsophalangeal joints with proximal sesamoid bones The prevalence of dorsoproximal phalanx one fragmentation (1.2%) of metacarpophalangeal joints were similar compared to other studies. Osteochondral fragmentation of proximal plantar phalanx one (6%) was 8.5 times more prevalent when compared to proximal palmar phalanx one (0.7%). The latter prevalence is in agreement with similar studies. There were low incidences of subchondral cyst-like lesions seen in distal third metacarpus (0.4%), distal third metatarsus (0.2%) and proximal first phalanx, similar to other studies. The most common change recorded on the dorsal aspect of distal third metacarpus and metatarsus was a well-defined semi-circular notch (dorsal aspect of distal third metacarpus 20.3%; dorsal aspect of distal third metatarsus 27%) similar to other studies. Our study showed a higher prevalence of lucencies present at dorsal aspect of distal third metacarpus (8.5%) and metatarsus (4.2%) compared to other studies. There was a marked lower prevalence in the current study of flat distal palmar third metacarpal condyles (6%). Prevalence of palmar and plantar third metacarpal and metatarsal supracondylar lysis were markedly higher in the present study. Slight palmar and plantar third metacarpus and metatarsus supracondylar lysis was seen in 19.3% of the horses. Moderate to extreme palmar and plantar third metacarpus and metatarsus supracondylar lysis were present in 10.2% of the horses. The carpi There was a higher prevalence of dorsomedial carpal disease in our study population (11.3%) and prevalence of carpal osseous cyst-like lesions such as a circular lucency in ulnar carpal bone was lower (14%). A markedly higher prevalence of 4.2% in carpal osteochondral fragmentation was found. The tarsi Osteochondrosis of the tarsocrural joint showed a similar prevalence (13.4 %). Degenerative joint disease of tarsometatarsal joint had a higher prevalence (36%) than the centrodistal (distal intertarsal) joint (20.3%). There was also a higher incidence of degenerative joint disease in tarsometatarsal joint (36%). The stifle In the current study, osteochondrosis of the stifle had a similar prevalence (3.6%) when compared to other studies. 6 Conclusion In South Africa Thoroughbred racehorse yearlings, radiographic changes most commonly involved the metacarpo- and metatarsophalangeal joints, carpi and tarsi. This study revealed markedly higher prevalence of palmar and plantar third metacarpal and metatarsal supracondylar lysis (slight 19.3% and moderate to extreme 10.2%), carpal osteochondral fragmentation (4.2%) and degenerative joint disease in tarsometatarsal joint (36%). Establishment of normal prevalence and distribution of radiographic changes in South Africa Thoroughbred yearlings will allow for comparison with populations of young horses worldwide. Knowledge of the normal prevalence will assist veterinarians to identify joints in which radiographic changes are most likely to occur.
Dissertation (MSc)--University of Pretoria, 2013.
gm2014
Companion Animal Clinical Studies
unrestricted

There have been numerous reports of vaccinated horses that contract fatal African horse sickness due to African horse sickness virus (AHSV) serotypes that are included in the current commercial vaccine used in southern Africa, which emphasizes the importance of thorough characterization of the equine immune response to AHSV. In particular, there are concerns about possible interference between vaccine strains in the polyvalent vaccine which led us to hypothesise that the administration of individual AHSV serotypes could induce a better immunity to individual serotypes than that achieved with the current polyvalent vaccines. There is also little published information describing the half-life of maternally derived neutralising antibody in foals to the nine AHSV serotypes. This is important for revising and developing vaccination protocols for foals of vaccinated mares. Given the lethality of both natural and experimental AHSV infections in horses, several aspects of immunity induced by different types of AHSV vaccines were evaluated. The neutralising antibody response of horses (foals) immunized with a commercial modified live virus (MLV) AHSV vaccine was evaluated and compared to the immune response elicited to monovalent MLV AHSV serotypes. Foals were immunized with either the polyvalent AHSV vaccine, or one of four monovalent vaccines containing individual AHSV serotypes 1, 4, 7 and 8. There were marked differences in the immunogenicity of individual virus serotypes contained in the vaccine. Foals more consistently seroconverted to AHSV 1 and responses to other serotypes were highly variable, and often weak or not detected. The serotype-specific responses of foals given the monovalent MLV vaccines were similar to those of foals given the polyvalent preparation suggesting that there is no apparent enhanced immune response through the administration of a monovalent vaccine as opposed to the polyvalent vaccine. Furthermore, the immunogenicity of individual AHSV serotypes contained in the commercial MLV vaccine varies remarkably. Neutralising antibody titres to the 9 known serotypes of AHSV were determined in a cohort of brood mares that were regularly vaccinated with the MLV AHSV vaccine, and the passive transfer and rate of decay of maternal antibody to the individual virus serotypes in their foals were measured. Similar to the data obtained from immunized foals, there was marked variation in the neutralising antibody response of the mares to individual AHSV serotypes even after repeated vaccination. This was mirrored in the duration of maternally-derived antibodies in their respective foals. In an effort to further characterize cellular immune (CMI) responses to AHSV, the immunity in horses induced by an experimental canarypox virus vectored recombinant (ALVAC®-AHSV4) vaccine was characterised. The detection of VP2/VP5 specific IFN-γ responses was assessed by enzyme-linked immune spot (ELISpot) assay and clearly demonstrated that all ALVAC®-AHSV4 vaccinated horses developed significant IFN-γ production compared to unvaccinated horses. Flow cytometry demonstrated that this vaccine induced mainly CD8+ T-cells, able to recognize multiple T-cell epitopes throughout all of VP2 and only the N-terminus portion of VP5. In summary, the antibody and cellular response of horses to different AHSV vaccines was evaluated and compared. The results are relevant to the design of more efficacious AHSV vaccines and to identification of protective immunity in horses to this virus.
Thesis (PhD)--University of Pretoria, 2013.
gm2014
Veterinary Tropical Diseases
unrestricted

A retrospective investigation of Thoroughbred racehorses euthanazed as result of catastrophic musculoskeletal injury (CMI) at four racetracks in Gauteng, South Africa during the period of 1998-2004 was performed. Fifty-five cases of CMI from 103 603 starts were evaluated. The incidence of CMI per 1000 starts was 0.53, similar to the incidence reported worldwide. The affected limb of 32 of 55 horses with a CMI was evaluated radiographically, ultrasonographically and dissected. CMI occurred unilaterally and predominantly in the forelimbs, the left forelimb (LF) being most commonly affected. The suspensory apparatus, particularly the proximal sesamoid bones (PSB) was predominantly affected, mostly in the LF. Sixty-nine percent of the PSB fractures occurred biaxially, the medial PSB most commonly affected. PSB fractures were often associated with extensive damage to the flexor tendons and ligaments of the metacarpophalangeal joint. Lateral condylar fractures were more common than medial, and the right forelimb predominantly affected. Significant risk factors for CMI in this study were gender, racing interval, and weight carried. Gender relative to the number of starts had the highest statistical significance (intact males P<0.001 and geldings P=0.010). Intact males were 14.8 times more at risk than females and 5.3 times moreso than geldings. Horses carrying more than 59kg were 3.3 times more at risk of breakdown than horses carrying 54-59kg of weight (P=0.006). Horses with a racing interval of less than one week were approximately three times more at risk than those with longer intervals (P=0.025 and P=0.029 respectively). Statistically insignificant risk factors were racing year, going, distance, racetrack, age, size of field and draw. It is of paramount importance that CMI is strictly monitored and risk factors identified to implement preventative measures to circumvent occurrence of CMI, which may have a negative impact on this important spectator sport. This study provides benchmarks for the racing industry to monitor racetrack fatalities in Gauteng and to evaluate intervention strategies. Copyright
Dissertation (MMedVet)--University of Pretoria, 2009.
Companion Animal Clinical Studies
unrestricted

After Horses is a a collection of narrative and verse poems centered loosely around the idea or theme of how to create meaning from the fracture and detritus of daily life. Also under obsessive consideration throughout: loneliness, the risk of human connection, the risk of a lack of human connection, the impossibility of language, hope as illuminating and good thing, hope as desperate and devouring thing, and an underlying fear and awareness of the fact that no one can be sure of what ultimately matters, anyway.
Master of Fine Arts

Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2002.
Includes bibliographical references (leaves 136-140).
This thesis proposes a framework to model intervention in education systems using technology: the Learning Atmosphere. The motivation is to show that innovative learning with expressive technologies can happen even in economically disadvantaged regions, such as public education systems in Brazil, where our case studies took place. The contribution of the thesis is to explore ways in which mutual enrichment can be achieved through collective displacements of habits and mindsets taken for granted. The case studies demonstrate the importance and possibility of a powerful learning experience that builds up from the local culture and expertise, elements often disregarded in schools. Technology plays a central role, enabling diverse and innovative ways of working, expressing and building. In addition, it makes possible epistemological diversity, empowering of students and fulfillment to teachers, reinforcing the community's own livelihood. The core elements within the Learning Atmosphere are: -- Enhance the concept of generative themes using technology. -- Mix and match expressive media, especially low-cost technologies. -- Invest on relationship building and challenge established power relations. The legend of the Trojan Horse has the important role of warning us against the easy way into schools, the trivialization of ideas and the superficial experiences that do not change the praxis and mindsets in schools.
Paulo Blikstein.
S.M.

One of the most meaningful duties of poetry is to examine small moments in life—the fleeting, the transitory, the quotidian—and make them sacred. Its title derived from a conflation of the colloquialism “Close only counts in horseshoes and hand grenades,” Horse Grenade is concerned with questions of identity and proximity—physical, mental, and emotional—which weave themselves throughout my work. I am intrigued by the fluctuating correlation between spiritual closeness and temporal distance, the way it defies definition and logic. In an effort to address this phenomenon, I immerse the reader into foreign cultures and the frequently extreme circumstances of everyday life. In doing so, I seek invention, but also return to familial relationships and personal experience, ranging from rediscovering my heritage to my father breaking into nuclear power plants. My intention as a poet is to make honest and unique observations, developing them into a deeper understanding.

Object and tasks of work: 1. Analyse and summarize literature about horse coat color and it genetic background. 2. Perform phenotypical analysis of Lithuanian Heavy Darught horse coat color polymorphism. 3. Introduce horse MC1R gene research methodology at K. Janušauskas Laboratory of Animal Genetics, LVA. 4. Investigate MC1R gene polymorphism and distribution of different alleles at Lithuanian heavy draught by PCR-RFLP method. 5. Determine correlation between restriction fragment lenght polymorphism (RFLP) in MC1R gene and horse bay coat color polymorhism. Research methodology: 1. DNA extraction from hair roots. 2. PCR to amplify MC1R gene. 3. RFLP method-MC1R – enzyme Tag I. 3. Electrophoresis in agarose gel. 4. Staining with Etidium bromide. 5. Genotyping. 6. Stasitical analysis of data. Results and conclutions: The following DNA restriction fragments were obtained for the MC1R – Tag I polymorphism: PCR product - 460 bp; genotypes E/E; ea/ea – 460 bp; genotypes e/e – 275 bp; 185 bp; genotypes E/e; e/ea – 460 bp; 275 bp; 185 bp. After phenotypical investigation of coat color from 32 Lithuanian Heavy draught horses following variation have been found: light bay, bay, dark bay, roan and chesnut. Light bay horses with different intensivity of coat color comprised 84,4 %. From total investigated animals 34.4 % had e/e genotype, E/e – 12.5 %, e/ea - 50 % and E/E genotype – 3.1 %. Two different genotypes e/e (40.7 %) and e/ea (59.3) were found among bay color horses... [to full text]

In order to investigate the effect of food restriction on fat mobilization in horses with impaction in left ventral colon during treatment, serum triglycerides, NEFA and total bilirubine (TB) were measured before and after treatment. On another side, the determination of alcohol dehydrogenase (ADH) activity in serum could facilitate the distinguishing of the non-strangulating intestinal obstruction from the potential fatal strangulation obstruction and could submit a new prognostic biochemical parameter for intestinal strangulation. With the intention of giving a highlight over the analgesic effect of Buscopan® compositum in horses with colic, it was attempted to investigate the effect of Buscopan® compositum on the intestinal motility of healthy conscious horses in different regions of intestine. A significant elevation of NEFA and TB was observed in horses with impaction in left ventral colon at admission. By relieving the impaction, there was a significant elevation of triglycerides in comparison to its level at admission. There was a significant increase in ADH activity in all horses with acute intestinal obstruction. ADH activity was significantly higher in horses with strangulation in comparison to non-strangulation obstruction. There was only a significant correlation between ADH and lactate in horses with non-strangulation obstruction and colon torsion. Only AST and GLDH were significantly increased in horses with colon torsion. ADH activity > 20 U/l had 80.56% specificity and 80.49% sensitivity for discriminating horses with intestinal strangulation from non-strangulation obstruction. ADH activity < 80 U/l had 94.44% specificity and 66.67% sensitivity for survival. Buscopan® compositum had an immediate, rapid and significant (p< 0.05) reduction of duodenal, cecal and left ventral colon contractions after application. Cecal and left ventral colon contractions restored rapidly their normal contractions after 30 min, while duodenal contractions returned to the normal rate after 120 min of Buscopan® compositum administration. The horses with impaction in left ventral colon are susceptible to fat mobilization during the period of treatment as a result of food restriction. It was characterized by a revisable hypertri-glyceridemia and hyperbililrubinemia. Serum ADH activity could have a useful clinical value in detecting the intestinal strangulation and predicting the prognosis in horses with intestinal strangulation. Buscopan® compositum at its therapeutic dosage has an immediate, potent, short-lived reductive effect on cecum and left ventral colon contractions but a minor, longer effect on the duodenal contractions. Therefore, it is thought to be more effective in treatment of spasmodic colic than in large colon impaction
Um den Effekt der Nahrungskarenz auf die Fettmobilisation bei Pferden mit Verstopfung der linken ventralen Längslagen des Kolons während der Behandlung zu untersuchen, wurden Triglyceride (TG), freie Fettsäuren (FFS) und Gesamtbilirubin (GB) bestimmt. Andererseits ermöglicht die Bestimmung der Aktivität der Alkoholdehydrogenase (ADH) im Serum die Unterscheidung zwischen einer nichtstrangulierenden intestinalen Obstruktion und einer potentiell tödlichen Strangulation. ADH kann somit als ein neuer prognostischer biochemischer Parameter für die intestinale Strangulation eingesetzt werden. Um den spasmolytischen Effekt von Buscopan compositum bei Pferden mit Kolik zu untersuchen, wurde der Effekt von Buscopan compositum auf die intestinale Kontraktion von gesunden Pferden in verschiedenen Regionen des Darmes getestet. Eine signifikante Erhöhung der FFS und des GB wurde bei Aufnahme von Pferden mit einer Verstopfung in der linken ventralen Längslagen festgestellt. Nach der Behandlung der Verstopfung konnte eine signifikante Erhöhung der Konzentration von TG, bezogen auf die TG Konzentration bei Aufnahme in die Klinik, festgestellt werden. Bei Pferden mit akuter intestinaler Obstruktion wurde eine signifikante Erhöhung der Aktivität der ADH beobachtet. Die Aktivität der ADH war bei Pferden mit einer Strangulation signifikant höher als bei Pferden, die eine nichtstrangulierende Obstruktion des Darmes hatten. Bei Pferden mit einer nichtstrangulierenden Obstruktion oder einer Kolontorsion wurde eine positive Korrelation zwischen der ADH-Aktivität und der Laktatkonzentration im Serum festgestellt. Nur bei Pferden mit Kolontorsion waren die Aktivitäten von AST und GLDH signifikant erhöht. Für die Unterscheidung zwischen Pferden mit einer intestinalen Strangulation oder einer nichtstrangulierenden Obstruktion wurde für die ADH- Aktivität größer als 20 U/l eine Spezifität von 80,56% und eine Sensitivität von 80,49% ermittelt. Eine ADH-Aktivität kleiner 80 U/l zeigt, mit einer Spezifität von 94,44% und einer Sensitivität von 66,67%, eine günstige Prognose für das Überleben des Pferdes an. Nach Gabe von Buscopan® compositum trat eine sofortige schnelle und signifikante (p<0,05) Reduktion der Kontraktionen im Duodenum, Zäkum und den linken ventralen Längslagen ein. Die Kontraktionen des Zäkums und der linken ventralen Längslagen normalisierten sich schnell innerhalb von 30 min, wogegen die Kontraktionen des Duodenums erst 120 min nach der Applikation von Buscopan® compositum den Normalzustand erreichten. Pferde mit einer Verstopfung in der linken ventralen Längslagen des Kolons sind während der medizinischen Behandlung anfällig für Fettmobilisation aufgrund der reduzierten Futter-aufnahme. Dies ist gekennzeichnet durch eine reversible Hypertriglyceridämie und eine Hyperbilirubinämie. Die Aktivität von ADH im Serum kann ein nützlicher klinischer Parameter sein, um eine intestinale Strangulation zu identifizieren und bietet sich auch als prognostischer Marker bei intestinaler Strangulation an. Die Applikation von Buscopan® compositum in der therapeutischen Dosierung hat eine sofortige, potente und kurzzeitige Reduktion der Kontraktionen des Zäkums und der linken ventralen Längslage aber einen geringen und länger anhaltenden Effekt auf die duodenalen Kontraktionen zur Folge. Daraus folgt, dass Buscopan® compositum bei der Behandlung von Krampfkoliken effektiver ist als bei Verstopfungen des großen Kolons

Fokus i studien ligger på terapeuters val av metod och synen på hästen som terapeutiskt resurs. Detta görs genom kvalitativ deskriptiv ansats. Terapeuterna intervjuas genom semistrukturerad intervjuguide med öppna frågor. Arthurs teori om vilka typer av terapeuter som, utifrån personlighet och epistemologiska uppfattningar, är disponerade till en viss typ av terapeutisk inriktning, användes för att försöka förklara varför de terapeuter som arbetar med HUT, väljer den metoden. Resultatet visar att terapeuternas val av HUT metod inte kunde förklaras genom Arthur's teori. Resultatet visar också att hästen som terapeutisk resurs förändrar terapin på flera områden och gör att terapeutens roll förändras. Forskningsfältet är under utveckling, och denna studie kan ge ökad förståelse för vad hästunderstödd terapi inom det psykoterapeutiska spektrat innebär och terapeuters syn på val av metod och hästen och som terapeutisk resurs. Förslag till fortsatt forskning är vad som förenar de terapeuter som väljer att arbeta med hästen som terapeutisk resurs, samt hästens roller i psykoterapi och kartläggande studier av vilka olika delar hästunderstödd terapi består av.

Two replicated experiments (Exp. 1: May 14 to June 8; Exp.2: June 25 to July 20) evaluated effects of feeding grain to 2-yr-old Quarter horses on behavior and physiological parameters during early stages of training. In each experiment, 6 different horses were allotted by sex and weight to 2 diets; hay only or hay plus 2.3 kg/d grain. Horses were group-housed with ad libitum access to grass/alfalfa hay and water, and were individually fed 1.15 kg grain or 40 g salt (placebo) at 0800 and 1600 for 7 d prior to and during training. The trainer was blind to diet assignments. Horses were trained 5 d/wk for 3 wk and scored (1 to 5) by the trainer daily on obedience (willingness to ride with a loose rein and little leg pressure), life (willingness to move at any desired speed), and direction (suppleness in the poll and loin), while an observer scored fearfulness. A heart monitor recorded minimum, maximum, and mean heart rate daily during training. Categorical data were transformed by subtracting the daily median as each horse's score was relative to the other horses on that day. Data were analyzed as repeated measures (Proc Mixed of SAS) with horse as the experimental unit. In Exp. 1 grain did not affect (P = 0.83) obedience, while horses fed grain in Exp. 2 were less obedient during training (P = 0.02) than those not receiving grain. Horses fed grain showed greater (P = 0.05) fearfulness than horses fed hay alone. Life:direction (ideal is 1.0, > 1.0 indicates high self-preservation) was higher (P = 0.04) in horses fed grain than in those fed hay alone (1.29 vs. 1.08, respectively). Maximum heart rate was not affected (P = 0.21) by grain, while mean heart rate was higher (P = 0.03) for horses fed grain than hay alone (126 vs. 119 beats/min, respectively). Horses fed grain during training exhibited more self-preservation behavior, increased mean heart rate, and an unbalanced life to direction ratio, which could inhibit training effectiveness.

Thesis (Ph. D.)--Sverges lantbruksuniversitet, 2001.
Thesis statement in Swedish and English abstract inserted. Based on 4 previously prepared or published papers reprinted here. Includes bibliographical references.

The Horse Latitudes is a collection of stories that documents one infantry squad's time in Baghdad, Iraq. The missions are long stretches of boredom, broken up by flashes of violence. The single sniper shot fired. An IED loosely buried in the roadside, waiting. A schoolyard of kids throwing fist-sized rocks at gun-trucks. The enemy is vast and changing. The downtime is a combination of homesickness, RPGs, and mortar fire. These men suffer through the war, heat, and each other. These stories look into the fire-fights and their aftermath to get to soldiers' struggles within themselves: how to fight a faceless enemy, what it means to serve, how one soldiers, what makes a man, what makes a good man, what will it mean to die here, and what does it mean not to. This collection dismisses what we think we know about war -- violence, camaraderie, masculinity, enemy, victory -- in order to tell a harder, truer story.

A decline in railroad-building occurred in the 20th century, which made the world think of railways as something attributed to the 19th century. In the 21st century, however, so many new railway projects are planned all over the world, that I choose to call this ‘the world’s second wave of railway development’. Because of this, the development of the discipline studying railroads’ effects on democracy, peace and war has grown immensely in importance. I try to contribute to this discipline by studying railroads’ effects on democracy in small nation-states, and specifically in Jordan. I do this by conducting a theory-testing, comparative study, using the before-after research design and congruence method and by comparing Jordan with Sweden and Albania. My theory is that railroads lead to democracy and is constituted by several theories of effects of railways and Seymour Martin Lipset’s Modernization Theory. I show that railroads have promoted democracy or changes in democratic direction in all three of the studied cases and then discuss and compare these results in an analysis along with an answer to my question. I make some remarks about further studies and think that this essay is a precursor to future process-tracing studies.

This essay aims to show how anthropomorphism, and also to some extent zoomorphism, is created in Nicholas Evans’s novel The Horse Whisperer.  Through parallel events and the usage of the concepts horse whisperers and horse whispering, a special connection is created between Grace, the main human character, and Pilgrim, the main horse character. This essay argues that their connection grounds for the reader to see the horse anthropomorphically and the human to some extent zoomorphically. With the use of Daston and Mitman’s notions of anthropomorphism and zoomorphism, this essay analyses how the concepts manifest themselves in the novel. The definition of horse whisperers and horse whisperering within this essay derives from the work of Brannaman and Parelli, this due to their theoretical value and knowledge about horse whispering.

Two times are critical for the horse ¾ the first few days of its life and the last few moments of a race. Vitamin E is critical in regard to immune competence in the first and antioxidant status in the latter. Studies conducted at the Middleburg Agricultural Research and Extension (MARE) Center include the development of horse feeds that replace sugar and starch with fat and fiber. The previous fat source of the pasture supplement under development was corn oil, which contains much vitamin E, was replaced with a cereal by product, which contains relatively little. Vitamin E has been studied in horses to a limited degree but not in grazing Thoroughbreds, thus the MARE Center gave me the opportunity to study vitamin E in Thoroughbred mares and foals. Middleburg is located in the Blue Ridge Mountains on Northern Virginia close to the site of one of the toughest endurance races in the world. This allowed me the opportunity to study vitamin E and antioxidant status in the horse during endurance racing. Initial studies of vitamin E supplementation to mares during the last trimester of gestation were disconcerting with no changes in serum concentrations of a-tocopherol (vitamin E). Studies conducted during the post-partum period revealed evidence of responses to vitamin E supplementation, as increased a-tocopherol concentrations were observed in mares' milk and in foal serum. Foals are born with virtually no circulatory antibodies and the supplementation of a synthetic form of vitamin E to mares demonstrated an increased passive transfer of immunoglobulins to foals. Natural vitamin E has shown a greater bioavailability than synthetic forms, in other species and was tested here at the MARE Center on mares. A greater passive transfer of immunoglobulins was observed with natural vitamin E supplementation compared with the synthetic forms, with immunoglobulin M concentrations in foal serum remaining higher for a longer period after birth compared to foals of non-supplemented mares. The transfer of a-tocopherol via the milk was also increased in concentration and duration in mares supplemented with natural vitamin E. Bioavailability of five oral forms of vitamin E (3 natural and 2 synthetic) were tested and one natural form was also administered intravenously so that clearance of vitamin E could be used to calculate the efficiency of absorption of the oral forms. Efficiency of absorption for oral treatments was not determined because of the slow turnover time of the intravenously administered vitamin E, which confounded all subsequent baseline serum a-tocopherol concentrations. Of the salvageable data, serum a-tocopherol concentrations were higher in grouped treatments at 9 and 12 h post dosing. Lipid fractions revealed possible insufficient absorption of the oral doses of vitamin E and possibly tissue saturation following intravenous doses of vitamin E. Serum concentrations of a-tocopherol were generally higher following natural forms of oral vitamin E administration. As vitamin E is the most important antioxidant in cells, it is often supplemented to endurance horses competing in 80 and 160 km races. Vitamin E protects lipid cell membranes from peroxidation by free radicals, which are increased during strenuous exercise resulting in oxidative stress. The antioxidant status of horses is severely tested during endurance racing and so a study was conducted to monitor changes in circulating antioxidants during three endurance races. Interesting novel findings in the horse were the maintenance of serum a-tocopherol and the depletion of erythrocyte glutathione and plasma ascorbate during two 80 km and one 160 km races. Associations were found between increased muscle cell enzyme leakage and decreased antioxidant status during endurance exercise and although associations do not prove a causation of oxidative stress, they do provide motivation to search for a cause and it is tempting to propose that oxidative stress damaged muscle cell membranes in endurance horses. Further, these findings propose a connection between muscle cell damage and a new form of exertional rhabdomyolysis (ER) that has been observed in endurance horses, where oxidative fibers are damaged compared to the typical glycolytic fiber damage associated with known forms or ER. An increased understanding of vitamin E utilization in the horse will improve the health and welfare of all horses, but especially newborn foals and the athletic endurance horses.
Ph. D.

A capacidade aeróbica dos equinos atletas pode ser explica, em partes, pelo seu desenvolvimento cardíaco associado ao treinamento físico. O exame ecocardiográfico de equinos atletas permite a visualização destas alterações e da função cardíaca destes animais. Buscou-se avaliar ecocardiograficamente equinos de diferentes modalidades esportivas, para verificar se o tipo de atividade física desempenhada por cada grupo de animais promove diferenças estruturais ou funcionais cardíacas. 196 equinos foram submetidos à avaliação ecocardiográfica em repouso, sendo divididos em três grupos: grupo Polo, 44 equinos participantes de provas de Polo; grupo QM, 49 equinos da raça Quarto de Milha, participantes de provas de baliza e tambor, e grupo PSI, 103 equinos da raça Puro Sangue Inglês participantes de provas de corridas. Foram avaliados os seguintes índices cardíacos: SIV, DIVE e PLVE em sístole e diástole, AE em sístole, Ao em diástole, relação AE:Ao, FEj, VEj, VSFVE, VDFVE, FS%, E-S, TEVE, DC e FC. Os animais do grupo PSI apresentaram os maiores volumes de ventrículo esquerdo, tendo apresentado proporcionalmente menor eficiência quando analisado o VEj. Os animais do grupo Polo e QM apresentaram melhores valores quando analisadas as variáveis de função cardíaca. A atividade física mais intensa desempenhada pelos animais do grupo QM e Polo permitiu melhor desenvolvimento funcional do coração destes animais, tendo o grupo PSI, apresentado valores que sugerem que sua capacidade aeróbica ainda pode ser melhor explorada através de melhor orientação de seu treinamento físico.
The aerobic capacity of equine athletes may be explained, in part, by its cardiac development associated with physical training. Echocardiographic examination of equine athletes allows the visualization of these changes and cardiac function of these animals. We aimed to evaluate echocardiographically horses of different sports to see if the type of physical activity performed by each group of animals promotes structural or functional cardiac differences. 196 horses underwent echocardiography at rest were divided into three groups: Polo group, 44 horses participating in tests of Polo; QM group, 49 horses of Quarter Horse, participants of barrel and pole bending events and PSI group, 103 horses of the breed Thoroughbred racehorses. We evaluated the following heart rates: IVS, LVD and LVFW in systole and diastole, LA in systole, Ao in diastole, mean LA: Ao, EF, EV, LVFSV, LVFDV, FS%, E-S, LVET, CO and HR. The PSI group animals showed higher left ventricular volumes and provided proportionately less efficiency when we analyzed EV. Animals in group Polo and QM showed higher values when variables such as cardiac function. The more intense physical activity performed by the animals of group QM and Polo provided better functional development of the heart of these animals, and the PSI group, presented figures suggesting that aerobic capacity can still be better exploited through better targeting of their physical training.