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Dissertations / Theses on the topic 'Host-virus relationships'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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1

Wang, Pui, and 王培. "Study of the host factors interacting with H5N1 influenza virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43085210.

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Wang, Pui. "Study of the host factors interacting with H5N1 influenza virus." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43085210.

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3

Baldridge, Gerald Don. "Molecular biology of Bunyavirus-host interactions." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184934.

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Ribonuclease T1 oligonucleotide fingerprint (ONF) analysis was used to study genomic stability of La Crosse virus (Bunyaviridae) during vertical and horizontal transmission in the laboratory. No RNA genomic changes were detected in vertebrate cell culture-propagated virus isolated (following oral ingestion and replication) from the natural mosquito host, Aedes triseriatus. Genomic changes were not detected during transovarial passage of virus through two generations of mosquitoes or in virus isolated from suckling mice infected by transovarially infected mosquitoes. These results demonstrate t

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4

Burgess, Shane Campbell. "Investigations into host cell-virus relationships and tumour immunity in Marek's disease." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324271.

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5

Crill, Wayne Douglass. "Experimental evolution and molecular basis of host-specific viral adaptation /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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6

Hadi, Buyung Asmara Ratna Flanders Kathy L. Bowen Kira L. "Aphid vectors and grass hosts of barley yellow dwarf virus and cereal yellow dwarf virus in Alabama and western Florida." Auburn, Ala., 2009. http://hdl.handle.net/10415/2018.

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7

Li, Tin-wai Olive. "Influenza polymerase subunit compatibility between human H1 and H5 viruses." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B41896890.

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8

Brown, J. K., and M. R. Nelson. "Transmission, Host Range and Virus-Vector Relationships of Chino del Tomate Virus (CdTV), a New Whitefly-transmitted Geminivirus of Tomato." College of Agriculture, University of Arizona (Tucson, AZ), 1988. http://hdl.handle.net/10150/214160.

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The transmission properties, host range, and virus- vector relationships of chino del tomate virus (CdTV), a new whitefly-transmitted geminivirus of tomato, are described. The virus is transmitted by B. tabaci, the sweet potato whitefly, but not by seed or sap. The virus infects members of the Asclepiadaceae, Leguminosae, Malvaceae, and Solanaceae. In virus-vector studies, minimum AAF and IAF times were 1 hour and 2 hours, respectively. The virus was retained by its whitefly vector for 4.5 and 7.3 days following 24- and 72-hr AAF respectively. Relative efficiencies of transmission for 1, 5, 10

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9

Maekawa, Akiko Medical Sciences Faculty of Medicine UNSW. "Characterisation of the immune co-receptor function of CD4." Publisher:University of New South Wales. Medical Sciences, 2007. http://handle.unsw.edu.au/1959.4/40498.

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CD4 is a co-receptor for binding of T cells to antigen-presenting cells (APC) and the primary receptor for human immunodeficiency virus-I. The disulfide bond in the second extracellular domain (D2) of CD4 is reduced on the cell surface, which leads to formation of disulfide-linked homodimers. A large conformational change must take place in D2 to allow for formation of the disulfide-linked dimer. Domain swapping of D2 is the most likely candidate for the conformational change leading to formation of two disulfide-bonds between Cysl30 in one monomer and Cysl59 in the other one (Cys133 and Cysl6

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10

Knez, Jozo Capone John P. "Characterization of the role of herpes simplex virus protein VP16 in viral gene expression through interactions with the virion host shutoff protein (VHS) and HCF-1/." *McMaster only, 2003.

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11

Li, Tin-wai Olive, and 李天慧. "Influenza polymerase subunit compatibility between human H1 and H5 viruses." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B41896890.

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12

Boyd, Ann Marie. "Interactions between common vertebrate hosts and the mosquito vectors of Ross River and Barmah Forest viruses in urban Brisbane, South East Queensland, Australia /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18059.pdf.

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13

Walter, Cheryl Tracy. "Establishing experimental systems for studying the replication biology of Providence virus." Thesis, Rhodes University, 2009. http://hdl.handle.net/10962/d1003987.

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Providence virus (PrV) is a member of the Tetraviridae, a family of small, positive sense, single-stranded RNA viruses, which characteristically infect the midgut tissue of heliothine larvae. PrV is the only known tetravirus that replicates in cultured insect cells. The virus comprises a monopartite genome resembling members of the genus Betatetravirus with the capsid precursor protein undergoing autoproteolytic cleavage at its C-terminus consistent with other tetravirus capsid precursor proteins. Analysis of viral cDNA predicted the presence of three potential overlapping gene products (from

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14

Wu, Jing Qin. "Microarray studies of HIV-host interactions in relation to disease status and therapy effects." Thesis, The University of Sydney, 2008. https://hdl.handle.net/2123/28129.

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HIV-host interactions can be interrogated at the level of both protein (proteome) and RNA (transcriptome). At protein level, previous studies have shown that expression levels of cell surface antigens such as CD38 and HLA-DR are related to HIV disease status as well as the efficacy of highly active antiretroviral therapy (HAART). To date, the immunophenotyping of cell surface antigens relies on flow cytometry, allowing estimation of 3-6 markers at a time. The recently described DotScan antibody microarray technology enables the simultaneous analysis of a large number of cell surface ant

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15

Kauffman, Anne Kathryn Marie. "Demographics of lytic viral infection of coastal ocean vibrio." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90046.

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Thesis: Ph. D., Joint Program in Biological Oceanography (Massachusetts Institute of Technology, Department of Civil and Environmental Engineering; and the Woods Hole Oceanographic Institution), 2014.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Viral predation on bacteria in the ocean liberates carbon from the particulate fraction, where it is accessible to higher trophic levels, and redirects it to the dissolved fraction, where it supports microbial growth. Although viruses are highly abundant in the ocean little is known about how their interactions wi

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16

Saayman, Michael John. "The establishment of a routine monitoring technique for detecting the most prevalent pathogenic viruses in river water, Western Cape, South Africa." Thesis, Cape Peninsula University of Technology, 2012. http://hdl.handle.net/20.500.11838/1497.

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Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Biomedical Technology in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology, 2012<br>In many developed countries worldwide the provision of safe, clean water is an expected commodity. In South Africa however, as in most developing countries, the access and supply of water safe for human consumption is challenged or complicated by pollution and more recently water availability. Point-source pollutants in surface- and groundwater are normally the most concentrated close

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17

Maluta, Nathalie Kristine Prado. "Respostas biológicas e comportamentais de Bemisia tabaci (Genn.) (Hemiptera: Aleyrodidae) a plantas de tomate infectadas com Tomato chlorosis virus (ToCV) e Tomato severe rugose virus (ToSRV) e atividades estiletares associadas à inoc." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/11/11146/tde-09082017-100910/.

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Vários fitovírus são capazes de influenciar o comportamento e desenvolvimento biológico de seus insetos vetores de modo a favorecer sua disseminação entre plantas hospedeiras, mas pouco se sabe a respeito dos efeitos de infecções virais sobre moscas-brancas Bemisia tabaci (Genn.), uma vez que se trata de um complexo de espécies, que transmite vírus de diferentes gêneros com distintos modos de transmissão. Considerando-se a importância de B. tabaci como praga e vetora e o grande prejuízo causado a diversos cultivos devido à transmissão de fitovírus, o presente trabalho teve como objetivos: a) I

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18

Haugen, Samuel Arthur McGrath. "Assessing Cereal Aphid Diversity and Barley Yellow Dwarf Risk In Hard Red Spring Wheat and Durum." Thesis, North Dakota State University, 2018. https://hdl.handle.net/10365/28791.

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Barley yellow dwarf (BYD), caused by Barley yellow dwarf virus and Cereal yellow dwarf virus, and is a yield limiting disease of small grains. A research study was initiated in 2015 to identify the implications of BYD on small grain crops of North Dakota. A survey of 187 small grain fields was conducted in 2015 and 2016 to assess cereal aphid diversity; cereal aphids identified included, Rhopalosiphum padi, Schizaphis graminum, and Sitobion avenae. A second survey observed and documented field absence or occurrence of cereal aphids and their incidence. Results indicated prevalence and incidenc

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19

James, Samantha. "Herpèsvirus de primates et de chauves-souris du nouveau monde : modèles d'étude des relations évolutives hôtes-virus DNA polymerase sequences of New World Monkey Cytomegaloviruses : another molecular marker with which to infer Platyrrhini systematics Novel herpesviruses of neotropical bats and their relationships with other members of the Herpesviridae family." Thesis, Guyane, 2019. http://www.theses.fr/2019YANE0004.

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Les virus appartenant à la famille Herpesviridae (ordre Herpesvirales) sont répartis au sein de trois sous-familles : Alpha-, Beta- et Gamma-herpesvirinae. Ils ont été identifiés à partir d’un large spectre d’espèces hôtes, allant des mammifères aux reptiles en passant par les oiseaux et ont la capacité de persister toute au long de la vie de l’hôte. La plupart de ces virus sont par ailleurs spécifiques d’une espèce hôte. La large distribution des herpèsvirus, associée à une infection généralement asymptomatique chez l’hôte naturel suggèrent que ces virus auraient co-évolué avec leurs hôtes.Mo

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20

Xing, Li. "Non-enveloped virus infection probed with host cellular molecules : a structural study /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-289-2.

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21

Teo, Chong Gee. "Analysis of the Epstein-Barr virus-host relationship by in situ hybridisation." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47684.

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22

Berard, Alicia. "Global quantitative host proteomic assay of infected cells highlight virus specific protein changes and identify a novel role for secretogranin ii protein in virus infections." ACS Publications, 2012. http://hdl.handle.net/1993/30717.

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Viruses are obligate parasites that use the host cellular machinery to produce progeny virions. The host responds to this invading pathogen by induction of the immune system; however, the virus employs a variety of strategies to overcome these attacks. The complexity of the virus-host interaction is of great interest to researchers with aims to both characterize the relationship and target steps of the viral life cycle to hinder infection. Many targeted tactics employ single protein analysis; however, approaches that examine the whole set of virus/host interactions are available. Transcription

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23

Sassi, Giovanna. "Relative quantification of host gene expression and protein accumulation upon turnip mosaic potyvirus infection in tobacco." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81433.

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Turnip mosaic virus (TuMV) infects a variety of crops, worldwide, including the economically relevant Brassicacea family. It was previously demonstrated that TuMV infection in tobacco protoplasts leads to an overall decrease of host protein. However, it remains unclear whether this phenomenon is due to the repression of plant gene transcription during the infection period or due to viral inhibition of host translation. In this study, quantification of various transcripts and protein products from infected tobacco was performed via real-time RT-PCR and ELISA. In comparison to the gamma-t

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24

Messias, Ueliton. "Atividade da superoxido dismutase, catalase, peroxidases e acumulo de H2O2 associados a infecção de um Carlavirus em soja e um Potyvirus no feijoeiro." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/315675.

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Orientador:Jorge Vega<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-12T04:10:59Z (GMT). No. of bitstreams: 1 Messias_Ueliton_D.pdf: 899792 bytes, checksum: c79dd05dd46e901a7add3fa66d7afc3f (MD5) Previous issue date: 2008<br>Resumo: As plantas defendem-se continuamente contra ataques de bactérias, vírus, fungos, invertebrados e de outras plantas. O estresse oxidativo é um tipo de resposta fisiológica da planta após o reconhecimento do patógeno, podendo resultar em sintomas nas plantas dependendo da sensibilidade do hosped

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25

Bojic, Teodora. "Host involvement in the replication of potato spindle tuber viroid and the evolutionary relationship between plant viroids and the hepatitis delta virus." Thesis, University of Ottawa (Canada), 2009. http://hdl.handle.net/10393/28353.

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The present study examines the interaction between host RNA polymerase II (RNAP II) and potato spindle tuber viroid (PSTVd), with the goal of locating and characterizing a putative RNAP II promoter within the viroid's RNA genome. By using a co-immunoprecipitation approach coupled with deletion and mutational analysis, RNAP II was shown to specifically bind the left terminal hairpin loop of PSTVd(+) RNA. The interaction with RNAP II appears to be dependent on PSTVd secondary structure features, rather than a particular sequence. These findings provide direct evidence of association between RNAP

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26

Norton, Amanda Mary. "Disentangling the Relationship Between Deformed wing virus, the Honey Bee Host (Apis mellifera) and the Viral Vector, the Ectoparasitic Mite Varroa destructor." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/25768.

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The ectoparasitic mite Varroa destructor is indisputably the most significant driver of global colony losses of the Western honeybee, Apis mellifera. Colony deaths are frequently attributed to Deformed wing virus (DWV), which is vectored by the mite. In this thesis I attempt to disentangle the tripartite relationship between DWV, A. mellifera and V. destructor, by investigating whether the two major DWV genotypes, A and B, differ from the point of view of the virus, the honey bee and the mite. First, I assessed the viral accumulation dynamics of multiple DWV genotypes during single or co-inf

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Devignot, Stéphanie. "Le Syndrome de choc de dengue, approches clinique et in vitro." Thesis, Aix-Marseille 2, 2010. http://www.theses.fr/2010AIX20672/document.

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Le syndrome de choc de dengue (DSS) est une complication potentiellement mortelle dela dengue, première arbovirose humaine et problème majeur de santé publiquemondial. Il survient chez une fraction des patients, et résulte d’une fuite plasmatiquemassive, non prédictible, dont la physiopathologie est mal connue. Le décryptage de laréponse de l’hôte est donc essentiel pour améliorer le pronostic et le traitement despatients. Ce travail de thèse a abordé les mécanismes de la fuite plasmatique du DSS dedeux façons : versant immunitaire et versant endothélial. D’une part, nous avons comparéen ex vi

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28

Enchéry, François. "Étude de la modulation de la voie canonique d'activation de NF-kB par les protéines non structurales du virus Nipah." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSEN093/document.

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Le virus Nipah (NiV) est un paramyxovirus zoonotique du genre Henipavirus, qui a émergé en 1998. NiV infecte l'homme et cause des troubles respiratoires et des encéphalites avec une forte létalité. A l’inverse, chez les hôtes naturels de NiV, les chauves-souris de la famille des Pteropodidae, l’infection est asymptomatique. Cependant, les mécanismes permettant aux Pteropodidae de contrôler l’infection sont inconnus à ce jour. NiV produit des protéines non structurales, V, W et C, qui sont des facteurs de virulence. V, W et C inhibent les voies de l’interféron de type 1. De plus, la protéine W

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Sikora, Dorota. "Hepatitis Delta Virus: Identification of Host Factors Involved in the Viral Life Cycle, and the Investigation of the Evolutionary Relationship Between HDV and Plant Viroids." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/22910.

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Hepatitis delta virus (HDV) is the smallest known human RNA pathogen. It requires the human hepatitis B virus (HBV) for virion production and transmission, and is hence closely associated with HBV in natural infections. HDV RNA encodes only two viral proteins - the small and the large delta antigens. Due to its limited coding capacity, HDV needs to exploit host factors to ensure its propagation. However, few human proteins are known to interact with the HDV RNA genome. The current study has identified several host proteins interacting with an HDV-derived RNA promoter by multiple approaches:

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30

Leobold, Matthieu. "Démonstration fonctionnelle de la nature virale des particules sans ADN de la guêpe parasitoïde venturia canescens." Thesis, Tours, 2018. http://www.theses.fr/2018TOUR4017.

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Chez la guêpe parasitoïde Venturia canescens, des particules virales dépourvues d'ADN appelées VLP (pour "Virus-like Particules") sont produites spécifiquement dans les ovaires et tapissent le chorion des oeufs qui sont injectés dans la chenille hôte. Les VLP ont une fonction immunosuppressive pour l'hôte parasité et permettent ainsi la survie des oeufs du parasitoïde. Ces VLP résultent de l’intégration d’un nudivirus dans le génome de l’ancêtre de la guêpe, nudivirus qui a été ensuite domestiqué pour former des liposomes viraux capables de véhiculer dans l’hôte des protéines de virulence d'or

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Oon, Aileen Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Molecular evolution of hepatitis C virus quasispecies." 2007. http://handle.unsw.edu.au/1959.4/40659.

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The viral dynamics of the hepatitis C virus (HCV) in newly acquired infection are not well understood. HCV exists within an individual as a spectrum of minor variants termed quasispecies. The evolution of minor variants may contribute to viral escape of the host?s immune response, thereby facilitating development of chronic infection. The hypervariable 1 region (HVR1) is the most heterogeneous part of the HCV genome and contains a putative B-cell epitope. Thus, diversity in HVR1 could be a strategy used to evade neutralising antibodies. Acutely infected individuals (n=24) were examined with th

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32

"The early host responses upon HBV replication." Thesis, 2010. http://library.cuhk.edu.hk/record=b6074821.

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Further functional investigation revealed that knockdown of GRP78 expression by RNA interference resulted in a significant increase of both intracellular and extracellular HBV virions in the transient HBV-producing HepG2 cells, concomitant with enhanced levels of hepatitis B surface antigen and e antigen in the culture medium Conversely, overexpression of GRP78 in HepG2 cells led to HBV suppression concomitant with induction of the positive regulatory circuit of GRP78 and interferon-beta 1 (IFN-beta1). In this connection, IFN-beta1-mediated 2', 5'-oligoadenylate synthetase (OAS) and ribonuclea

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33

Johnson, Karyn Nicole. "Molecular biology of Drosophila C Virus and studies on host susceptibility." Phd thesis, 1997. http://hdl.handle.net/1885/145395.

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34

Lee, Albert Kim. "Characterizing Immune Responses to Marburg Virus Infection in Animal Hosts Using Statistical Transcriptomic Analysis." Thesis, 2018. https://doi.org/10.7916/D8S19JFC.

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Marburg virus (MARV)–along with Ebola Virus–comprises Filoviridae, a family of virus which causes the life-threatening hemorrhagic fever in human and non-human primates for which there is no clinically approved vaccine. For this reason, this virus can potentially lend itself to pandemic and weapons of bioterrorism. Strikingly, this virus yields asymptomatic responses in its recently discovered host Rousettus aegyptiacus. Understanding of the interaction between MARV and different animal hosts will enable the improved understanding of filovirus immunology and the development of effective therap

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Maginnis, Melissa Sue. "Identification and characterization of cellular determinants of reovirus internalization." Diss., 2007. http://etd.library.vanderbilt.edu/ETD-db/available/etd-03302007-130416/.

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36

Rezende, Melo Da Silva Carolina. "The role of the viral host response modifiers SPI-2 and N1L in mousepox pathogenesis." Phd thesis, 2011. http://hdl.handle.net/1885/150288.

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The Orthopoxvirus genus includes highly-pathogenic viruses such as variola virus and ectromelia virus (ECTV). iECDTV is a natural pathogen of mice, causing mousepox and approximately 25% of its gene products are thought to be mediators of host immune evasion that target diverse processes.such as cellular signalling, intrinsic and extrinsic cell death pathways and components of the innate immune response. I studied the role of SPI-2 and NiL genes in mousepox and for that purpose recombinant ECTV were generated using GFP expression and blasticidin resistance as selection markers for transient d

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Guglielmi, Kristen Marie. "Structure-function analysis of mammalian orthoreovirus attachment protein [sigma]1." Diss., 2008. http://etd.library.vanderbilt.edu/ETD-db/available/etd-03242008-110238/.

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Tahiliani, Vikas. "Humoral immunity in secondary poxvirus infection." Phd thesis, 2010. http://hdl.handle.net/1885/151471.

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The studies described in this thesis have utilised the orthopoxvirus ectromelia (ECTV), a natural mouse pathogen that causes a disease termed mousepox, to address the roles of specific innate cell types and T cell subsets in virus control during a secondary infection and more importantly, whether CD4{u207A} T cell help is important for generation of protective recall antibody responses. There are 3 key reasons why the experiments detailed in this thesis were undertaken. First, much of our current understanding of the induction and maintenance of long-lived antibody responses is based on studie

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Wang, Gary Zhe. "Host factors regulating retroviral replication by interactions with viral RNA and DNA." Thesis, 2016. https://doi.org/10.7916/D8028RHK.

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Retroviruses are capable of infecting diverse vertebrates, and successful infection requires intimate interaction between virus and the host cell. During an infection, retroviral particles must bind specifically to cell surface receptors on the target cell, cross the plasma membrane, reverse-transcribe their RNA genome into double stranded DNA, find their way to the nucleus, enter the nucleus and integrate its DNA into host chromosomes. Following integration, expression of viral mRNA ensues, followed by viral mRNA export into the cytoplasm, translation of viral mRNA into proteins, and assembly

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Umbach, Jennifer Lin. "Analysis of the Interaction between Viruses, Mirnas and the Rnai Pathway." Diss., 2008. http://hdl.handle.net/10161/596.

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"Systemic lupus erythematosus: from immunopathology to viral pathogenesis." Thesis, 2008. http://library.cuhk.edu.hk/record=b6074590.

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Results of the above studies thus suggested that immune dysregulation in SLE result in derangement of a spectrum of inflammatory mediators leading to possible multiple organs auto-inflammatory damages. However, the exact etio-pathogenic mechanism could not simply be explained by these phenomena. Infection has been invoked as an underlying etiology or trigger for the induction of autoimmune disease. Epstein-Barr virus (EBV) possesses multiple features that characterise its involvement in initiating or perpetuating SLE disease. Several research groups demonstrated that the peripheral blood EBV D

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Byrd, Daniel James. "Vaccinia Virus Binding and Infection of Primary Human Leukocytes." Thesis, 2014. http://hdl.handle.net/1805/5279.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Vaccinia virus (VV) is the prototypical member of the orthopoxvirus genus of the Poxviridae family, and is currently being evaluated as a vector for vaccine development and cancer cell-targeting therapy. Despite the importance of studying poxvirus effects on the human immune system, reports of the direct interactions between poxviruses and primary human leukocytes (PHLs) are limited. We studied the specific molecular events that determine the VV tropism for major PHL subsets including monocytes, B cells, neutrophils, NK cells, and T

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Dias, Jose Alberto Caram de Souza. "The relationship of potato leafroll virus concentration in the host and vector to disease spread." 1988. http://catalog.hathitrust.org/api/volumes/oclc/20388123.html.

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Thesis (Ph. D.)--University of Wisconsin--Madison, 1988.<br>Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 310-339).

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Huang, Ching-Ing, and 黃瀞瑩. "The study of the relationship between Bamboo mosaic virus ?infection and its downregulated host gene NbTFIISL from Nicotiana benthamiana." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/33672067394055047419.

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碩士<br>國立中興大學<br>生物科技學研究所<br>102<br>Abstract Bamboo mosaic virus (BaMV) belongs to the Potexvirus genus of Flexiviridae family and has a single-stranded positive-strand RNA genome. To understand the infection mechanism BaMV, our lab has selectively detected and isolated 90 differentially expressed genes from Nicotiana benthamiana post BaMV infection using cDNA-Amplified Fragment Length Polymorphism (cDNA-AFLP) technique. In my study, one of the downregulated cDNA fragments, ACAC5-2, has no significant match to any known sequence in the databases. The relative coat protein accumulation level of

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Lanza, Andre Syd, and 藍安杰. "A Study on the Relationship between Nucleolar Localization of the Nervous Necrosis Virus Capsid Protein and Host Gene Expression." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/vp54vu.

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碩士<br>國立臺灣海洋大學<br>水產養殖學系<br>107<br>Nervous necrosis virus (NNV) is a devastating fish virus causing mass mortality in juvenile fish and causing significant economic losses in the grouper aquaculture industry in South East Asia. Treatment and control of the disease is difficult primarily because the molecular basis of pathogenicity of the virus is still not fully understood. It has previously been demonstrated that the viral capsid protein (CP) localizes to the nucleolus in fish cells signifying some role it may have in controlling gene expression of the host. We employed a PCR site-directed mu

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